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Wyszukujesz frazę ""Cell Hypoxia"" wg kryterium: Temat


Tytuł:
Hypoxic Effects on Matrix Metalloproteinases' Expression in the Tumor Microenvironment and Therapeutic Perspectives.
Autorzy:
Gonzalez-Avila G; Laboratorio de Oncología Biomédica, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Sommer B; Departamento de Investigación en Hiperreactividad Bronquial, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Flores-Soto E; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Coyoacán, Ciudad de México 04510, Mexico.
Aquino-Galvez A; Laboratorio de Biología Molecular, Departamento de Fibrosis Pulmonar, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 28; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/therapy
Neoplasms*/drug therapy
Humans ; Cell Hypoxia/genetics ; Tumor Microenvironment/genetics ; Hypoxia/genetics ; Hypoxia/metabolism ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
Czasopismo naukowe
Tytuł:
Hypoxia dose painting in SBRT - the virtual clinical trial approach.
Autorzy:
Schiavo F; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Toma-Dasu I; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Kjellsson Lindblom E; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2023 Oct; Vol. 62 (10), pp. 1239-1245. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
Radiosurgery*/methods
Neoplasms*
Humans ; Oxygen ; Hypoxia ; Computer Simulation ; Cell Hypoxia ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Novel cancer treatment paradigm targeting hypoxia-induced factor in conjunction with current therapies to overcome resistance.
Autorzy:
Kao TW; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.
Bai GH; Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei City, 100225, Taiwan.
Wang TL; Departments of Pathology, Oncology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans StreetRoom 306, Baltimore, MD, CRB221231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Shih IM; Departments of Pathology, Oncology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans StreetRoom 306, Baltimore, MD, CRB221231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chuang CM; Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, 112304, Taiwan.; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.; Department of Midwifery and Women Health Care, National Taipei University of Nursing and Health Sciences, Taipei, 112303, Taiwan.
Lo CL; Department of Biomedical Engineering, National Yang-Ming Chiao Tung University, Taipei, 112304, Taiwan.; Medical Device Innovation and Translation Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Tsai MC; Department of General Medicine, Taipei Medical University Hospital, Taipei, 110301, Taiwan.
Chiu LY; Department of General Medicine, Mackay Memorial Hospital, Taipei, 104217, Taiwan.
Lin CC; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; School of Medicine, College of Medicine, Taipei Medical University, Taipei City, 110301, Taiwan.
Shen YA; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .; International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jul 18; Vol. 42 (1), pp. 171. Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/pathology
Humans ; Hypoxia ; Cell Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
Czasopismo naukowe
Tytuł:
Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers.
Autorzy:
Liew LP; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.
Shome A; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Department of Ophthalmology, The University of Auckland, Auckland 1023, New Zealand.
Wong WW; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.
Hong CR; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.
Hicks KO; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.
Jamieson SMF; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.; Department of Pharmacology and Clinical Pharmacology, The University of Auckland, Auckland 1023, New Zealand.
Hay MP; Auckland Cancer Society Research Centre, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 31; Vol. 28 (11). Date of Electronic Publication: 2023 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Nitroimidazoles*/pharmacology
Radiation-Sensitizing Agents*/pharmacology
Neoplasms*/drug therapy
Neoplasms*/radiotherapy
Humans ; Cell Hypoxia ; Hypoxia
Czasopismo naukowe
Tytuł:
The Role of the Estrogen-Related Receptor Alpha (ERRa) in Hypoxia and Its Implications for Cancer Metabolism.
Autorzy:
Chaltel-Lima L; Segal Cancer Center, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Division of Experimental Medicine, McGill University, Montreal, QC H4A 3J1, Canada.
Domínguez F; Centro de Investigación Biomédica de Oriente (CIBIOR), Instituto Mexicano del Seguro Social (IMSS), Atlixco 74360, Mexico.
Domínguez-Ramírez L; Centro de Investigación Biomédica de Oriente (CIBIOR), Instituto Mexicano del Seguro Social (IMSS), Atlixco 74360, Mexico.
Cortes-Hernandez P; Centro de Investigación Biomédica de Oriente (CIBIOR), Instituto Mexicano del Seguro Social (IMSS), Atlixco 74360, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 28; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/genetics
Transcription Factors*/metabolism
Humans ; Cell Hypoxia ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Receptors, Estrogen/metabolism ; ERRalpha Estrogen-Related Receptor
Czasopismo naukowe
Tytuł:
Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF-2α-Dependent Manner.
Autorzy:
Qu M; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Long Y; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Wang Y; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.; Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, The University of Texas-Health Science Center at Houston, Houston, TX 77030, USA.
Yin N; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Zhang X; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Zhang J; The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing 100875, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 11; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Basic Helix-Loop-Helix Transcription Factors*/metabolism
Histones*/metabolism
Neoplasms*
Phosphoric Diester Hydrolases*/metabolism
Humans ; Cell Hypoxia ; Hypoxia/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
Probabilistic model checking of cancer metabolism.
Autorzy:
Friedenberg MD; Cornell University, Ithaca, NY, 14850, USA.
Lita A; National Cancer Institute, Bethesda, MD, 20892, USA.
Gilbert MR; National Cancer Institute, Bethesda, MD, 20892, USA.
Larion M; National Cancer Institute, Bethesda, MD, 20892, USA.
Celiku O; National Cancer Institute, Bethesda, MD, 20892, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 07; Vol. 12 (1), pp. 18870. Date of Electronic Publication: 2022 Nov 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural
MeSH Terms:
Glutamine*/metabolism
Neoplasms*/genetics
Neoplasms*/metabolism
Humans ; Models, Statistical ; Cell Hypoxia ; Glucose/metabolism
Czasopismo naukowe
Tytuł:
Targeting hypoxia in solid and haematological malignancies.
Autorzy:
Harris B; Experimental Cancer Medicine Team, Christie NHS Foundation Trust, Manchester, UK.
Saleem S; Haematology Department, Christie NHS Foundation Trust, Manchester, UK.
Cook N; Experimental Cancer Medicine Team, Christie NHS Foundation Trust, Manchester, UK.; Division of Cancer Sciences, University of Manchester, Manchester, UK.
Searle E; Haematology Department, Christie NHS Foundation Trust, Manchester, UK. .; Division of Cancer Sciences, University of Manchester, Manchester, UK. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Nov 02; Vol. 41 (1), pp. 318. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/pathology
Hematologic Neoplasms*
Animals ; Humans ; Cell Hypoxia ; Vascular Endothelial Growth Factor A/metabolism ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mammals/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
[ Cu]Cu-ATSM: an emerging theranostic agent for cancer and neuroinflammation.
Autorzy:
Xie F; PET Center, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Wei W; Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, 200127, China. .
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Oct; Vol. 49 (12), pp. 3964-3972.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Coordination Complexes*
Neoplasms*/diagnostic imaging
Neoplasms*/therapy
Organometallic Compounds*
Thiosemicarbazones*
Cell Hypoxia ; Copper Radioisotopes ; Humans ; Neuroinflammatory Diseases ; Positron-Emission Tomography ; Precision Medicine ; Radiopharmaceuticals/therapeutic use
Opinia redakcyjna
Tytuł:
Znhit1 and HIF-2α are correlated with cancer stem cell markers in breast cancer patients.
Autorzy:
Ebeid SA; Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Abd El Moneim NA; Department of Cancer Management and Research, Medical Research Institute, Alexandria University, Alexandria, Egypt.
El-Benhawy SA; Department of Radiation Sciences, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Ramadan R; Department of Experimental and Clinical Surgery, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Ismail SE; Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 17; Vol. 12 (1), pp. 13918. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/pathology
beta Catenin*/genetics
beta Catenin*/metabolism
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Phosphoproteins/*metabolism
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Cell Hypoxia ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplastic Stem Cells/metabolism ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Hypoxia and the Receptor for Advanced Glycation End Products (RAGE) Signaling in Cancer.
Autorzy:
Taneja S; Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND 58105, USA.
Vetter SW; Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND 58105, USA.
Leclerc E; Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND 58105, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 29; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cell Hypoxia*
Glycation End Products, Advanced/*metabolism
Neoplasms/*metabolism
Receptor for Advanced Glycation End Products/*physiology
Animals ; Cell Line, Tumor ; Humans
Czasopismo naukowe
Tytuł:
The close interaction between hypoxia-related proteins and metastasis in pancarcinomas.
Autorzy:
López-Cortés A; Programa de Investigación en Salud Global, Facultad de Ciencias de la Salud, Universidad Internacional SEK, 170302, Quito, Ecuador. .; Escuela de Medicina, Facultad de Ciencias de la Salud, Universidad de Las Américas, 170124, Quito, Ecuador. .; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain. .
Prathap L; Department of Anatomy, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, 600077, Chennai, India.
Ortiz-Prado E; One Health Research Group, Universidad de Las Américas, 170124, Quito, Ecuador.
Kyriakidis NC; One Health Research Group, Universidad de Las Américas, 170124, Quito, Ecuador.
León Cáceres Á; Heidelberg Institute of Global Health, Faculty of Medicine, University of Heidelberg, 69117, Heidelberg, Germany.
Armendáriz-Castillo I; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.; Instituto Nacional de Investigación en Salud Pública, 170136, Quito, Ecuador.; Facultad de Ingenierías y Ciencias Aplicadas, Universidad Internacional SEK, 170302, Quito, Ecuador.
Vera-Guapi A; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07747, Jena, Germany.
Yumiceba V; Institut Für Humangenetik Lübeck, Universität Zu Lübeck, 23562, Lübeck, Germany.
Simbaña-Rivera K; One Health Research Group, Universidad de Las Américas, 170124, Quito, Ecuador.; Latin American Network for Cancer Research (LAN-CANCER), Lima, Peru.
Echeverría-Garcés G; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.
García-Cárdenas JM; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.; Laboratorio de Ciencia de Datos Biomédicos, Escuela de Medicina, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, 170113, Quito, Ecuador.
Pérez-Villa A; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.
Guevara-Ramírez P; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.
Abad-Sojos A; BIOscience Research Group, Quito, Ecuador.
Bautista J; BIOscience Research Group, Quito, Ecuador.
Puig San Andrés L; BIOscience Research Group, Quito, Ecuador.
Varela N; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain.; Laboratory of Chemical Carcinogenesis and Pharmacogenetics, Department of Basic-Clinical Oncology, Faculty of Medicine, University of Chile, 8320000, Santiago, Chile.
Guerrero S; Latin American Network for the Implementation and Validation of Clinical Pharmacogenomics Guidelines (RELIVAF-CYTED), 28015, Madrid, Spain. .; Laboratorio de Ciencia de Datos Biomédicos, Escuela de Medicina, Facultad de Ciencias Médicas de la Salud y de la Vida, Universidad Internacional del Ecuador, 170113, Quito, Ecuador. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 30; Vol. 12 (1), pp. 11100. Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/pathology
Phosphatidylinositol 3-Kinases*/metabolism
Cell Hypoxia/genetics ; Cell Line, Tumor ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Neoplasm Metastasis ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/genetics ; Signal Transduction ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Detection of Hypoxia in Cancer Models: Significance, Challenges, and Advances.
Autorzy:
Godet I; The Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.; Johns Hopkins Institute for NanoBioTechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Doctorman S; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Wu F; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Gilkes DM; The Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.; Johns Hopkins Institute for NanoBioTechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.; Cellular and Molecular Medicine Program, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
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Źródło:
Cells [Cells] 2022 Feb 16; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Hypoxia*
Neoplasms*
Animals ; Cell Hypoxia ; Humans ; Mice ; Organoids
Czasopismo naukowe
Tytuł:
Carbonic Anhydrase IX Inhibitors as Candidates for Combination Therapy of Solid Tumors.
Autorzy:
Kalinin S; Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.; School of Pharmacy, University of Eastern Finland, 70211 Kuopio, Finland.; Medicinal Chemistry Center, Togliatti State University, 445020 Togliatti, Russia.
Malkova A; Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Sharonova T; Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Sharoyko V; Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.; Medicinal Chemistry Center, Togliatti State University, 445020 Togliatti, Russia.
Bunev A; Medicinal Chemistry Center, Togliatti State University, 445020 Togliatti, Russia.
Supuran CT; Neurofarba Department, Universita degli Studi di Firenze, 50019 Florence, Italy.
Krasavin M; Institute of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 14; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*pharmacology
Neoplasms/*drug therapy
Animals ; Cell Hypoxia/drug effects ; Combined Modality Therapy ; Humans ; Neoplasms/metabolism ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł:
Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges.
Autorzy:
Noman MZ; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .
Hasmim M; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .
Lequeux A; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .
Xiao M; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .
Duhem C; Centre Hospitalier du Luxembourg, Department of Hemato-Oncology, L-1526 Luxembourg City, Luxembourg. .
Chouaib S; INSERM U1186, Gustave Roussy Cancer Center, 94805 Villejuif, France. .; Thumbay Research Institute for Precision Medicine - Gulf Medical University, 4184 Ajman, UAE. .
Berchem G; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .; Centre Hospitalier du Luxembourg, Department of Hemato-Oncology, L-1526 Luxembourg City, Luxembourg. .
Janji B; Tumor Immunotherapy and Microenvironment (TIME) Group, Department of Oncology, Luxembourg Institute of Health, Luxembourg, L-1526 Luxembourg City, Luxembourg. .
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Źródło:
Cells [Cells] 2019 Sep 14; Vol. 8 (9). Date of Electronic Publication: 2019 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cell Hypoxia*/drug effects
Cell Hypoxia*/immunology
Immunotherapy*
Tumor Microenvironment*/drug effects
Tumor Microenvironment*/immunology
Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors
Mixed Function Oxygenases/*therapeutic use
Neoplasms/*therapy
Repressor Proteins/*therapeutic use
Humans
Czasopismo naukowe
Tytuł:
Hypoxia-Driven Immune Escape in the Tumor Microenvironment.
Autorzy:
Vito A; Department of Biochemistry and Biomedical Sciences, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
El-Sayes N; Department of Biochemistry and Biomedical Sciences, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
Mossman K; Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada.
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Źródło:
Cells [Cells] 2020 Apr 16; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cell Hypoxia*
Cell Death/*immunology
Immunotherapy/*methods
Neoplasms/*immunology
Neoplasms/*therapy
Tumor Microenvironment/*immunology
B-Lymphocytes/immunology ; Dendritic Cells/immunology ; Humans ; Killer Cells, Natural/immunology ; Macrophages/immunology ; Neoplasms/pathology ; Signal Transduction/genetics ; T-Lymphocytes/immunology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
HIF-Dependent Mechanisms of Relationship between Hypoxia Tolerance and Tumor Development.
Autorzy:
Dzhalilova DS; Federal State Budgetary Institution 'Research Institute of Human Morphology', Moscow, 117418, Russia. .
Makarova OV; Federal State Budgetary Institution 'Research Institute of Human Morphology', Moscow, 117418, Russia.
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2021 Oct; Vol. 86 (10), pp. 1163-1180.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis Regulatory Proteins/*metabolism
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Neoplasms/*metabolism
Neoplasms/*pathology
Oxygen/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Cell Hypoxia/physiology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Neoplasms/genetics ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Signal Transduction ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł:
HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells.
Autorzy:
Lee SH; Department of Otorhinolaryngology, Hospital Sultanah Bahiyah, KM6 Jalan Langgar, Alor Setar 05460, Kedah, Malaysia.
Golinska M; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; Department of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.
Griffiths JR; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
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Źródło:
Cells [Cells] 2021 Sep 09; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adaptation, Physiological/*physiology
Cell Hypoxia/*physiology
Hypoxia-Inducible Factor 1/*metabolism
Neoplasms/*metabolism
Animals ; Humans ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Spontaneous Cell Detachment and Reattachment in Cancer Cell Lines: An In Vitro Model of Metastasis and Malignancy.
Autorzy:
Vargas-Accarino E; Patologia Molecular Translacional, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Herrera-Montávez C; Patologia Molecular Translacional, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Ramón Y Cajal S; Patologia Molecular Translacional, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.; Anatomía Patológica, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.; CIBER de Cáncer (CIBERONC), Instituto de Salud Carlos III, Avenida de Monforte de Lemos 3-5, 28029 Madrid, Spain.
Aasen T; Patologia Molecular Translacional, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.; CIBER de Cáncer (CIBERONC), Instituto de Salud Carlos III, Avenida de Monforte de Lemos 3-5, 28029 Madrid, Spain.; Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 06; Vol. 22 (9). Date of Electronic Publication: 2021 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Neoplasms/*pathology
Animals ; Cell Adhesion/drug effects ; Cell Adhesion/genetics ; Cell Death/drug effects ; Cell Death/genetics ; Cell Hypoxia/drug effects ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Cell Shape/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Neoplasm Metastasis ; Neoplasms/genetics ; Protein Kinase Inhibitors/pharmacology ; Reproducibility of Results ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/metabolism ; rho-Associated Kinases/antagonists & inhibitors ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Tytuł:
Bridging cell-scale simulations and radiologic images to explain short-time intratumoral oxygen fluctuations.
Autorzy:
Kingsley JL; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; University of South Florida, Tampa, Florida, United States of America.
Costello JR; Department of Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.
Raghunand N; Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Rejniak KA; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Jul 26; Vol. 17 (7), pp. e1009206. Date of Electronic Publication: 2021 Jul 26 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Models, Biological*
Neoplasms/*diagnostic imaging
Neoplasms/*metabolism
Oxygen/*metabolism
Cell Hypoxia/physiology ; Computational Biology ; Computer Simulation ; Humans ; Mathematical Concepts ; Neoplasms/blood supply ; Radiography ; Systems Analysis ; Tumor Hypoxia/physiology ; Tumor Microenvironment/physiology
Czasopismo naukowe

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