Temat: "Cell Hypoxia" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: SENP1 attenuates hypoxia‑reoxygenation injury in liver sinusoid endothelial cells by relying on the HIF‑1α signaling pathway.
Autorzy:: Qing Z; General Surgery Department, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Luo Q; Department of Pediatrics, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Duan J; General Surgery Department, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Lin J; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Huang H; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Yang S; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.
Zeng Z; Organ Transplantation Center, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Apr; Vol. 29 (4). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelial Cells*/metabolism
Peptide Hydrolases*
Animals ; Mice ; Capillaries/metabolism ; Cell Hypoxia ; Hypoxia/metabolism ; Liver/metabolism ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism

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Skocz do pozycji: 2.

Tytuł:: Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines.
Autorzy:: Marallano VJ; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ughetta ME; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Tejero R; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nanda S; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ramalingam R; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Stalbow L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Sattiraju A; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Huang Y; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ramakrishnan A; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Shen L; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Wojcinski A; Pacific Neuroscience Institute and Saint John's Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, 90404, USA.
Kesari S; Pacific Neuroscience Institute and Saint John's Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, 90404, USA.
Zou H; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Tsankov AM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. .
Friedel RH; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7246. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Neoplasms*/genetics
Brain Neoplasms*/pathology
Glioma*/pathology
Glioblastoma*/pathology
Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Cell Line, Tumor ; Gene Expression Profiling ; Neoplastic Stem Cells/metabolism ; Cell Hypoxia/genetics

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Skocz do pozycji: 3.

Tytuł:: IFI16 Is Indispensable for Promoting HIF-1α-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions.
Autorzy:: Randle RK; Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN 37208, USA.; Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN 37208, USA.
Amara VR; Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN 37208, USA.; Department of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur 844102, Bihar, India.
Popik W; Center for AIDS Health Disparities Research, Meharry Medical College, Nashville, TN 37208, USA.; Department of Internal Medicine, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 15; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Podocytes*/metabolism
Renal Insufficiency, Chronic*/metabolism
Humans ; Apolipoprotein L1/genetics ; Apolipoprotein L1/metabolism ; Cell Hypoxia/genetics ; Chromatin Immunoprecipitation ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Phosphoproteins/genetics ; Phosphoproteins/metabolism

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Skocz do pozycji: 4.

Tytuł:: Lactiplantibacillus plantarum K8 lysates regulate hypoxia-induced gene expression.
Autorzy:: Jeong J; Department of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Kang BH; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Ju S; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Park NY; School of Life Sciences, BK21 FOUR KNU Creative BioRearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Kim D; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Dinh NTB; Department of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Lee J; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Rhee CY; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Cho DH; School of Life Sciences, BK21 FOUR KNU Creative BioRearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Kim H; Research and Development Center, Skin Biotechnology Center Co. Ltd., Yongin, 17104, Republic of Korea.
Chung DK; Graduate School of Biotechnology, Kyung Hee University, Yongin, 17104, Republic of Korea.
Bunch H; Department of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea. .; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6275. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroblastoma*
Humans ; Cell Hypoxia/genetics ; Cell Line ; Hypoxia/metabolism ; Gene Expression ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism

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Skocz do pozycji: 5.

Tytuł:: Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers.
Autorzy:: Sone K; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan.; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Sakamaki Y; Graduate School of Pharmaceutical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Hirose S; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan.; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Inagaki M; Graduate School of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Tachikawa M; Graduate School of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Yoshino D; Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.
Funamoto K; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan. .; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan. .; Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8597, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 02; Vol. 14 (1), pp. 5164. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelial Cells*/physiology
Glucose*/pharmacology
Humans ; Hypoxia ; Oxygen ; Cell Movement ; Cell Hypoxia ; Cells, Cultured

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Skocz do pozycji: 6.

Tytuł:: Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance.
Autorzy:: Pucci G; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Minafra L; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Bravatà V; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Calvaruso M; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Turturici G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Cammarata FP; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Savoca G; Radiation Oncology, ARNAS-Civico Hospital, 90100 Palermo, Italy.
Abbate B; Radiation Oncology, ARNAS-Civico Hospital, 90100 Palermo, Italy.
Russo G; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.
Cavalieri V; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.
Forte GI; Institute of Molecular Bioimaging and Physiology (IBFM)-National Research Council (CNR), Cefalù Secondary Site, C/da Pietrapollastra-Pisciotto, 90015 Cefalù, Italy.; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Viale delle Scienze Bld.17, 90128 Palermo, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/genetics
Glioblastoma*/radiotherapy
Glioblastoma*/metabolism
Glucose Transporter Type 3*/genetics
Glucose Transporter Type 3*/metabolism
Humans ; Biomarkers/metabolism ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Gene Knockdown Techniques ; Hypoxia

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Skocz do pozycji: 7.

Tytuł:: The HIF-1α/EGF/EGFR Signaling Pathway Facilitates the Proliferation of Yak Alveolar Type II Epithelial Cells in Hypoxic Conditions.
Autorzy:: Wang B; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
He J; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Cui Y; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.; Gansu Province Livestock Embryo Engineering Research Center, Department of Clinical Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Yu S; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.; Gansu Province Livestock Embryo Engineering Research Center, Department of Clinical Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Zhang H; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Wei P; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.
Zhang Q; Laboratory of Animal Anatomy & Tissue Embryology, Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:: Journal Article
MeSH Terms:: Epidermal Growth Factor*/metabolism
Signal Transduction*
Animals ; Cattle ; Cell Hypoxia/physiology ; Cell Proliferation ; Epithelial Cells/metabolism ; ErbB Receptors/metabolism ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Oxygen/metabolism

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Skocz do pozycji: 8.

Tytuł:: Endothelial Cell Apoptosis but Not Necrosis Is Inhibited by Ischemic Preconditioning.
Autorzy:: Zalewski J; Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Szajna M; John Paul II Hospital, 31-202 Krakow, Poland.
Stępień K; Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.; Department of Thromboembolic Disorders, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Nowak K; Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.; Department of Thromboembolic Disorders, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Karcińska A; Student Research Group, Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Yika ADC; Student Research Group, Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Krawczyk K; Student Research Group, Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Karwat K; Department of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Zalewska M; Department of Emergency Medicine, Faculty of Health Science, Jagiellonian University Medical College, 31-126 Krakow, Poland.
Pierzchalski P; Faculty of Health Science, Jagiellonian University Medical College, 31-126 Krakow, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 19; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Ischemic Preconditioning*
Humans ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Necrosis/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Hypoxia/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Cell Hypoxia

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Skocz do pozycji: 9.

Tytuł:: HIF-1α/MMP-9 Axis Is Required in the Early Phases of Skeletal Myoblast Differentiation under Normoxia Condition In Vitro.
Autorzy:: Chellini F; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Imaging Platform, University of Florence, 50134 Florence, Italy.
Tani A; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Imaging Platform, University of Florence, 50134 Florence, Italy.
Parigi M; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Imaging Platform, University of Florence, 50134 Florence, Italy.
Palmieri F; Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Florence, Italy.
Garella R; Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Florence, Italy.
Zecchi-Orlandini S; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Imaging Platform, University of Florence, 50134 Florence, Italy.
Squecco R; Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Florence, Italy.
Sassoli C; Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, Imaging Platform, University of Florence, 50134 Florence, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Dec 16; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Matrix Metalloproteinase 9*/metabolism
Myoblasts, Skeletal*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Animals ; Mice ; Cell Differentiation ; Oxygen ; Cell Hypoxia

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Skocz do pozycji: 10.

Tytuł:: Hypoxia-mimetic by CoCl2 increases SLC7A5 expression in breast cancer cells in vitro.
Autorzy:: Canhasi L; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, 701 82, SE, Sweden.
Tina E; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, 701 82, SE, Sweden.; Department of Clinical Research Laboratory, Faculty of Medicine and Health, Örebro University, Örebro, 701 82, SE, Sweden.
Eremo AG; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, 701 82, SE, Sweden. .; Department of Clinical Research Laboratory, Faculty of Medicine and Health, Örebro University, Örebro, 701 82, SE, Sweden. .; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2023 Dec 11; Vol. 16 (1), pp. 366. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:: Journal Article
MeSH Terms:: Large Neutral Amino Acid-Transporter 1*
Breast Neoplasms*/genetics
Humans ; Female ; Cell Hypoxia/genetics ; Cobalt/pharmacology ; MCF-7 Cells ; Hypoxia

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Skocz do pozycji: 11.

Tytuł:: Hypoxic Effects on Matrix Metalloproteinases' Expression in the Tumor Microenvironment and Therapeutic Perspectives.
Autorzy:: Gonzalez-Avila G; Laboratorio de Oncología Biomédica, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Sommer B; Departamento de Investigación en Hiperreactividad Bronquial, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Flores-Soto E; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Coyoacán, Ciudad de México 04510, Mexico.
Aquino-Galvez A; Laboratorio de Biología Molecular, Departamento de Fibrosis Pulmonar, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Calzada de Tlalpan 4502, Col. Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 28; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neoplasms*/therapy
Neoplasms*/drug therapy
Humans ; Cell Hypoxia/genetics ; Tumor Microenvironment/genetics ; Hypoxia/genetics ; Hypoxia/metabolism ; Matrix Metalloproteinases/genetics ; Matrix Metalloproteinases/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism

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Skocz do pozycji: 12.

Tytuł:: HIF-1α promotes kidney organoid vascularization and applications in disease modeling.
Autorzy:: Peng K; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.
Xie W; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.
Wang T; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China.
Li Y; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.
de Dieu Habimana J; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing, 100049, China.
Amissah OB; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing, 100049, China.
Huang J; Department of Anatomy and Neurobiology, Xiangya School of Medicine, Central South University, Changsha, China.
Chen Y; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.
Ni B; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China. .
Li Z; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. li_.; Department of Anatomy and Neurobiology, Xiangya School of Medicine, Central South University, Changsha, China. li_.; GZMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China. li_.; GIBH-CUHK Joint Research Laboratory On Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Guangzhou, China. li_.; NHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, China. li_.; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2023 Nov 19; Vol. 14 (1), pp. 336. Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:: Journal Article
MeSH Terms:: Organoids*/blood supply
Organoids*/metabolism
Kidney*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Models, Biological*
Angiogenesis*/drug effects
Angiogenesis*/physiopathology
Multipotent Stem Cells ; Humans ; Plasmids/genetics ; Gene Expression ; Stem Cells/cytology ; Stem Cells/metabolism ; Receptors, Vascular Endothelial Growth Factor/metabolism ; Angiogenesis Inhibitors/pharmacology ; Axitinib/pharmacology ; Cells, Cultured ; Cisplatin/pharmacology ; Cell Hypoxia ; Kidney Diseases/physiopathology

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Skocz do pozycji: 13.

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Skocz do pozycji: 14.

Tytuł:: NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways.
Autorzy:: Roennfeldt AE; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA 5006, Australia.
Allen TP; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.
Trowbridge BN; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.; Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.
Beard MR; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.; Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.
Whitelaw ML; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.; ASEAN Microbiome Nutrition Centre, National Neuroscience Institute, Singapore 169857, Singapore.
Russell DL; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA 5006, Australia.
Bersten DC; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA 5006, Australia.
Peet DJ; School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Oct 19; Vol. 13 (10). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcription Factors*/genetics
Gene Expression Regulation*
Humans ; Response Elements ; Nuclear Proteins/genetics ; Hypoxia/genetics ; Cell Hypoxia/genetics

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Skocz do pozycji: 15.

Tytuł:: Hypoxia dose painting in SBRT - the virtual clinical trial approach.
Autorzy:: Schiavo F; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Toma-Dasu I; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Kjellsson Lindblom E; Department of Physics, Stockholm University, Stockholm, Sweden.; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.; Pokaż więcej
Źródło:: Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2023 Oct; Vol. 62 (10), pp. 1239-1245. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:: Journal Article
MeSH Terms:: Radiosurgery*/methods
Neoplasms*
Humans ; Oxygen ; Hypoxia ; Computer Simulation ; Cell Hypoxia ; Tumor Microenvironment

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Tytuł:: Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway.
Autorzy:: Zhu X; Department of Cardiology, Shanghai University of Medicine & Health Sciences affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Wu Y; Department of Cardiology, Shanghai University of Medicine & Health Sciences affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Zhang X; Department of Cardiology, Shanghai University of Medicine & Health Sciences affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Gu W; Department of Cardiology, Shanghai University of Medicine & Health Sciences affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Ning Z; Department of Cardiology, Shanghai University of Medicine & Health Sciences affiliated Zhoupu Hospital, No.1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China. .; Pokaż więcej
Źródło:: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2023 Sep 26; Vol. 18 (1), pp. 265. Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Myocardial Reperfusion Injury*/drug therapy
Myocardial Reperfusion Injury*/prevention & control
Myocardial Reperfusion Injury*/metabolism
Myocytes, Cardiac*/metabolism
Animals ; Rats ; Apoptosis ; Caspase 3/metabolism ; Cell Hypoxia ; Hypoxia/drug therapy ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Sirtuin 1 ; Superoxide Dismutase/metabolism

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Tytuł:: Immunohistochemistry and oxygen saturation endoscopic imaging reveal hypoxia in submucosal invasive esophageal squamous cell carcinoma.
Autorzy:: Minakata N; Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan.
Sakashita S; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Wakabayashi M; Biostatistics Division, Center for Research Administration and Support, National Cancer Center, Kashiwa, Japan.
Nakamura Y; Department of Strategic Programs, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Sunakawa H; Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.; NEXT Medical Device Innovation Center, National Cancer Center Hospital East, Kashiwa, Japan.
Yoda Y; Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.; Department of Gastroenterology and Endoscopy, Saitama Cancer Center, Saitama, Japan.
Ishii G; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan.
Yano T; Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.; Course of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, Bunkyo-ku, Japan.; NEXT Medical Device Innovation Center, National Cancer Center Hospital East, Kashiwa, Japan.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 15809-15819. Date of Electronic Publication: 2023 Jun 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Esophageal Squamous Cell Carcinoma*
Esophageal Neoplasms*/diagnostic imaging
Esophageal Neoplasms*/pathology
Humans ; Immunohistochemistry ; Glucose Transporter Type 1 ; Oxygen Saturation ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit ; Cell Hypoxia ; Tumor Microenvironment

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Skocz do pozycji: 18.

Tytuł:: Unravelling the Collective Calcium Dynamics of Physiologically Aged Astrocytes under a Hypoxic State In Vitro.
Autorzy:: Mitroshina EV; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Krivonosov MI; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Pakhomov AM; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.; Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences (IAP RAS), 603950 Nizhny Novgorod, Russia.
Yarullina LE; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Gavrish MS; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Mishchenko TA; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Yarkov RS; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.
Vedunova MV; Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603022 Nizhny Novgorod, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 31; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: Astrocytes*/metabolism
Calcium/metabolism ; Cell Hypoxia ; Cellular Senescence ; Cells, Cultured ; Calcium Signaling ; Mice, Inbred C57BL ; Animals ; Mice

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Skocz do pozycji: 19.

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Skocz do pozycji: 20.

Tytuł:: Novel cancer treatment paradigm targeting hypoxia-induced factor in conjunction with current therapies to overcome resistance.
Autorzy:: Kao TW; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.
Bai GH; Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei City, 100225, Taiwan.
Wang TL; Departments of Pathology, Oncology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans StreetRoom 306, Baltimore, MD, CRB221231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Shih IM; Departments of Pathology, Oncology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 1550 Orleans StreetRoom 306, Baltimore, MD, CRB221231, USA.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chuang CM; Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, 112304, Taiwan.; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.; Department of Midwifery and Women Health Care, National Taipei University of Nursing and Health Sciences, Taipei, 112303, Taiwan.
Lo CL; Department of Biomedical Engineering, National Yang-Ming Chiao Tung University, Taipei, 112304, Taiwan.; Medical Device Innovation and Translation Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Tsai MC; Department of General Medicine, Taipei Medical University Hospital, Taipei, 110301, Taiwan.
Chiu LY; Department of General Medicine, Mackay Memorial Hospital, Taipei, 104217, Taiwan.
Lin CC; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; School of Medicine, College of Medicine, Taipei Medical University, Taipei City, 110301, Taiwan.
Shen YA; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .; International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jul 18; Vol. 42 (1), pp. 171. Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neoplasms*/drug therapy
Neoplasms*/pathology
Humans ; Hypoxia ; Cell Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism

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