Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Cell Line, Tumor"" wg kryterium: Temat


Tytuł:
Statistical Assessment of Drug Synergy from In Vivo Combination Studies Using Mouse Tumor Models.
Autorzy:
Mao B; Crown Bioscience Inc., Suzhou, Jiangsu, P.R. China.
Guo S; Crown Bioscience Inc., Suzhou, Jiangsu, P.R. China.
Pokaż więcej
Źródło:
Cancer research communications [Cancer Res Commun] 2023 Oct 23; Vol. 3 (10), pp. 2146-2157.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Line, Tumor*
Animals ; Mice ; Humans ; Disease Models, Animal ; Drug Therapy, Combination
Czasopismo naukowe
Tytuł:
The OSUMMER lines: A series of ultraviolet-accelerated NRAS-mutant mouse melanoma cell lines syngeneic to C57BL/6.
Autorzy:
Murphy BM; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio, USA.
Jensen DM; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio, USA.
Arnold TE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio, USA.; Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Aguilar-Valenzuela R; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio, USA.; Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Hughes J; EMD Millipore Corporation, Temecula, California, USA.
Posada V; Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Nguyen KT; Center for Genomic and Precision Medicine, Texas A&M Institute of Biosciences and Technology, Houston, Texas, USA.
Chu VT; EMD Millipore Corporation, Temecula, California, USA.
Tsai KY; Departments of Pathology and Tumor Biology, The H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA.
Burd CJ; Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Burd CE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio, USA.; Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
Pokaż więcej
Źródło:
Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2023 Sep; Vol. 36 (5), pp. 365-377. Date of Electronic Publication: 2023 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Line, Tumor*/radiation effects
Melanoma*/drug therapy
Melanoma*/genetics
Melanoma*/pathology
Animals ; Mice ; GTP Phosphohydrolases/genetics ; Membrane Proteins/genetics ; Mice, Inbred C57BL ; Mutation/genetics ; Proto-Oncogene Proteins B-raf/genetics
Czasopismo naukowe
Tytuł:
Label-free tumor cells classification using deep learning and high-content imaging.
Autorzy:
Piansaddhayanon C; Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, 10330, Thailand.; Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.; Chula Intelligent and Complex Systems, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Koracharkornradt C; Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Laosaengpha N; Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, 10330, Thailand.; Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Tao Q; NVIDIA AI Technology Center, Singapore, Singapore.
Ingrungruanglert P; Center of Excellence for Stem Cell and Cell Therapy, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Israsena N; Center of Excellence for Stem Cell and Cell Therapy, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .; Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .
Chuangsuwanich E; Department of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, 10330, Thailand. .; Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .
Sriswasdi S; Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .; Center for Artificial Intelligence in Medicine, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. .
Pokaż więcej
Źródło:
Scientific data [Sci Data] 2023 Aug 26; Vol. 10 (1), pp. 570. Date of Electronic Publication: 2023 Aug 26.
Typ publikacji:
Dataset; Journal Article
MeSH Terms:
Cell Line, Tumor*/classification
Cell Line, Tumor*/pathology
Neoplasms*/diagnostic imaging
Neoplasms*/pathology
Humans ; Area Under Curve ; Deep Learning ; Microscopy
Czasopismo naukowe
Tytuł:
Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue.
Autorzy:
Kim SC; Korean Cell Line Bank, Laboratory of Cell Biology, Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea.; Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Cho YE; Korean Cell Line Bank, Laboratory of Cell Biology, Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea.
Shin YK; Korean Cell Line Bank, Laboratory of Cell Biology, Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea.; Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Yu HJ; Department of Neurosurgery, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Chowdhury T; Department of Neurosurgery, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Kim S; Department of Neurosurgery, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Yi KS; Department of Radiology, Chungbuk National University Hospital and Chungbuk National University College of Medicine, Cheongju, Chung Buk, 28644, Republic of Korea.
Choi CH; Department of Radiology, Chungbuk National University Hospital and Chungbuk National University College of Medicine, Cheongju, Chung Buk, 28644, Republic of Korea.; Chungbuk National University College of Medicine, Cheongju, Chung Buk, 28644, Republic of Korea.
Cha SH; Department of Radiology, Chungbuk National University Hospital and Chungbuk National University College of Medicine, Cheongju, Chung Buk, 28644, Republic of Korea. .; Chungbuk National University College of Medicine, Cheongju, Chung Buk, 28644, Republic of Korea. .
Park CK; Department of Neurosurgery, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. .
Ku JL; Korean Cell Line Bank, Laboratory of Cell Biology, Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. .; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea. .; Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. .; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Korea. .
Pokaż więcej
Źródło:
Scientific data [Sci Data] 2023 Jul 12; Vol. 10 (1), pp. 448. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:
Dataset; Journal Article
MeSH Terms:
Brain Neoplasms*/genetics
Glioblastoma*/genetics
Cell Line, Tumor*
Genes, Neoplasm*
Humans ; Genomics ; Mutation
Czasopismo naukowe
Tytuł:
Multiscale optical phase fluctuations link disorder strength and fractal dimension of cell structure.
Autorzy:
Rancu A; Department of Biomedical Engineering, Duke University, Durham, North Carolina.
Chen CX; Department of Biomedical Engineering, Duke University, Durham, North Carolina.
Price H; Department of Biomedical Engineering, Duke University, Durham, North Carolina.
Wax A; Department of Biomedical Engineering, Duke University, Durham, North Carolina. Electronic address: .
Pokaż więcej
Źródło:
Biophysical journal [Biophys J] 2023 Apr 04; Vol. 122 (7), pp. 1390-1399. Date of Electronic Publication: 2023 Mar 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fractals*
Cell Line, Tumor*/cytology
Microscopy, Phase-Contrast*
Humans ; Phenotype
Czasopismo naukowe
Tytuł:
[Construction of TRAF6 ubiquitin site 331 mutant colorectal cancer cell stable line and its effect on biological behavior of colorectal cancer cells].
Autorzy:
He RF; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Wang Q; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou 350005, China.
Lin CL; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Lin PH; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou 350005, China.
Chen H; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou 350005, China.
Huang YJ; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Yang SG; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Ye JX; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Zhu GW; Department of Gastrointestinal Surgery 2 Section, the First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China.
Pokaż więcej
Źródło:
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2023 Feb 23; Vol. 45 (2), pp. 129-137.
Typ publikacji:
English Abstract; Journal Article
MeSH Terms:
Cell Line, Tumor*
Colorectal Neoplasms*/pathology
TNF Receptor-Associated Factor 6*/genetics
TNF Receptor-Associated Factor 6*/metabolism
Humans ; Cell Movement ; Cell Proliferation ; Lysine/metabolism ; NF-kappa B/metabolism ; Transcription Factor AP-1/metabolism ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł:
Androgen receptor inhibition suppresses anti-tumor neutrophil response against bone metastatic prostate cancer via regulation of TβRI expression.
Autorzy:
Alsamraae M; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Costanzo-Garvey D; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Teply BA; Fred & Pamela Buffett Cancer Center, Omaha, NE, USA; Division of Oncology & Hematology/Oncology, Department of Internal Medicine, University of Nebraska Medical Center Omaha, NE, USA.
Boyle S; Fred & Pamela Buffett Cancer Center, Omaha, NE, USA.
Sommerville G; Dana Farber Cancer Institute, Boston, MA, USA.
Herbert ZT; Dana Farber Cancer Institute, Boston, MA, USA.
Morrissey C; University of Washington, Seattle, WA, USA.
Dafferner AJ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Abdalla MY; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Fallet RW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Kielian T; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Jensen-Smith H; Fred & Pamela Buffett Cancer Center, Omaha, NE, USA; Eppley Institute for Research in Cancer and Allied Diseases, Omaha, NE, USA.
deOliveira EI; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Chen K; Laboratory of Cancer Innovation, National Cancer Institute, Frederick, MD, USA.
Bettencourt IA; Laboratory of Cancer Innovation, National Cancer Institute, Frederick, MD, USA.
Wang JM; Laboratory of Cancer Innovation, National Cancer Institute, Frederick, MD, USA.
McVicar DW; Laboratory of Cancer Innovation, National Cancer Institute, Frederick, MD, USA.
Keeley T; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Yu F; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA.
Cook LM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA; Fred & Pamela Buffett Cancer Center, Omaha, NE, USA. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216468. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Prostatic Neoplasms*/metabolism
Bone Neoplasms*/drug therapy
Bone Neoplasms*/secondary
Male ; Humans ; Receptors, Androgen/metabolism ; Androgens ; Neutrophils/metabolism ; Androgen Antagonists/pharmacology ; Androgen Antagonists/therapeutic use ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Oncolytic adenovirus as pancreatic cancer-targeted therapy: Where do we go from here?
Autorzy:
Yoon AR; Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea; Institute of Nano Science and Technology (INST), Hanyang University, Seoul, Republic of Korea; Hanyang Institute of Bioscience and Biotechnology (HY-IBB), Hanyang University, Seoul, Republic of Korea.
Hong J; GeneMedicine Co., Ltd., 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea.
Jung BK; GeneMedicine Co., Ltd., 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea.
Ahn HM; GeneMedicine Co., Ltd., 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea.
Zhang S; Department of Medical Oncology, Yanbian University Hospital, Jilin, China.
Yun CO; Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea; Institute of Nano Science and Technology (INST), Hanyang University, Seoul, Republic of Korea; Hanyang Institute of Bioscience and Biotechnology (HY-IBB), Hanyang University, Seoul, Republic of Korea; GeneMedicine Co., Ltd., 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216456. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Oncolytic Virotherapy*
Oncolytic Viruses*/genetics
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/therapy
Pancreatic Neoplasms*/pathology
Humans ; Adenoviridae/genetics ; Cell Line, Tumor ; Tumor Microenvironment
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł:
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer.
Autorzy:
Primeaux M; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Liu X; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE, USA.
Gowrikumar S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Fatima I; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Fisher KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Bastola D; Department of Bioinformatics, University of Nebraska Omaha, Omaha, NE, USA.
Vecchio AJ; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, NE, USA.
Singh AB; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA; VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA.
Dhawan P; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA; Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA; VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216479. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Humans ; Cell Line, Tumor ; Claudin-1/genetics ; Claudin-1/metabolism ; Drug Resistance, Neoplasm ; Signal Transduction ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
Precise delivery of celastrol by PEGylated aptamer dendrimer nanoconjugates for enormous therapeutic effect via superior intratumor penetration over antibody counterparts.
Autorzy:
Niu B; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Wu Y; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Zhou M; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Lin R; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Ge P; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Chen X; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Zhou H; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China. Electronic address: .
Zhang X; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China.
Xie J; School of Pharmaceutical Sciences, and Fujian Provincial Key Laboratory of Innovative Drug Target Research, Xiamen University, Xiang'an South Road, Xiamen, Fujian, 361102, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216461. Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Dendrimers*
Aptamers, Nucleotide*
Humans ; Animals ; Mice ; Nanoconjugates ; Drug Delivery Systems/methods ; Cell Line, Tumor ; Antibodies ; Oligonucleotides ; Polyethylene Glycols
Czasopismo naukowe
Tytuł:
SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest.
Autorzy:
Wang C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Wang T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Department of Urology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, 510900, China.
Li KJ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Hu LH; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Li Y; Laboratory Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Yu YZ; Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510500, China.
Xie T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Zhu S; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China.
Fu DJ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Wang Y; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China.
Zeng XZ; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Liu FP; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China.
Chen H; Luoyang Key Laboratory of Organic Functional Molecules, College of Food and Drug, Luoyang Normal University, Luoyang, Henan, 471934, China.
Chen ZS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
Feng NH; Department of Urology, Jiangnan University Medical Center, Wuxi, 214002, China; Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China. Electronic address: .
Liu J; Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
Jiang Y; Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
Zhao SC; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510500, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216464. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Histones*/genetics
Histones*/metabolism
Prostatic Neoplasms*/genetics
Prostatic Neoplasms*/pathology
Male ; Humans ; Lysine/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Methyltransferases/metabolism ; Cell Cycle Checkpoints/genetics ; Cell Proliferation ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Small molecule inhibition of TFF3 overcomes tamoxifen resistance and enhances taxane efficacy in ER+ mammary carcinoma.
Autorzy:
Guo H; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Tan YQ; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Huang X; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Zhang S; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Basappa B; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore, 570006, India.
Zhu T; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; The CAS Key Laboratory of Innate Immunity and Chronic Disease, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Pandey V; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China. Electronic address: .
Lobie PE; Tsinghua Berkeley Shenzhen Institute and the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China; Shenzhen Bay Laboratory, Shenzhen 518055, Guangdong, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 579, pp. 216443. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Carcinoma*
Humans ; Female ; Tamoxifen/pharmacology ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Neoplasm Recurrence, Local ; Taxoids/pharmacology ; Trefoil Factor-3/metabolism ; Trefoil Factor-3/pharmacology
Czasopismo naukowe
Tytuł:
The AEG-1-USP10-PARP1 axis confers radioresistance in esophageal squamous cell carcinoma via facilitating homologous recombination-dependent DNA damage repair.
Autorzy:
Zhao X; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Ma Y; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Li J; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Sun X; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Sun Y; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Qu F; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Shi X; Department of Radiation Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Xie Y; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Liu S; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Ma Y; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Ji C; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Hu W; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China.
Che S; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China. Electronic address: .
Zhang X; Department of Radiation Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yanta West Road, Xi'an, Shaanxi, 710061, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216440. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Squamous Cell Carcinoma*/radiotherapy
Esophageal Squamous Cell Carcinoma*/pathology
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/radiotherapy
Esophageal Neoplasms*/pathology
Carcinoma, Squamous Cell*/genetics
Carcinoma, Squamous Cell*/radiotherapy
Carcinoma, Squamous Cell*/pathology
Humans ; Astrocytes ; Radiation Tolerance/genetics ; Cell Line, Tumor ; DNA Repair ; Recombinational DNA Repair ; DNA Damage ; Ubiquitin Thiolesterase/genetics ; Poly (ADP-Ribose) Polymerase-1/genetics
Czasopismo naukowe
Tytuł:
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail.
Autorzy:
Yang J; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.
Liao Y; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.
Wang B; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin Medical University Cancer Hospital, Harbin, 150080, China.
Cui L; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.
Yu X; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.
Wu F; Translational Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin, 150080, China; Department of Gastroenterology, The First Affiliated Hospital of Harbin Medical University, Harbin, 150000, China.
Zhang Y; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin Medical University Cancer Hospital, Harbin, 150080, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin Medical University Cancer Hospital, Harbin, 150080, China; Translational Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin, 150080, China. Electronic address: .
Liu R; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China. Electronic address: .
Yao Y; Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin Medical University Cancer Hospital, Harbin, 150080, China; Translational Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin, 150080, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216427. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ubiquitin-Protein Ligases*/genetics
Ubiquitin-Protein Ligases*/metabolism
Colonic Neoplasms*/genetics
Humans ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Cell Line, Tumor ; Ubiquitination ; Epithelial-Mesenchymal Transition/genetics ; Edar-Associated Death Domain Protein/genetics ; Edar-Associated Death Domain Protein/metabolism
Czasopismo naukowe
Tytuł:
The deubiquitinating enzyme USP19 facilitates hepatocellular carcinoma progression through stabilizing YAP.
Autorzy:
Tian Z; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.
Xu C; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.
He W; Department of Urology, Xijing Hospital, Air Force Medical University, Xi'an, China.
Lin Z; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.
Zhang W; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China; Chinese Education Ministry's Key Laboratory of Western Resources and Modern Biotechnology, Key Laboratory of Biotechnology Shaanxi Province, College of Life Sciences, Northwest University, Xi'an, China.
Tao K; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.
Ding R; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China.
Zhang X; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China. Electronic address: .
Dou K; Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216439. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Humans ; Protein Processing, Post-Translational ; Ubiquitin/metabolism ; Deubiquitinating Enzymes/genetics ; Cell Line, Tumor ; Endopeptidases/metabolism
Czasopismo naukowe
Tytuł:
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade.
Autorzy:
Zhang Q; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; Department of Scientific Research, Jiangsu Cancer Hospital & the Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Zheng L; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, PR China.
Bai Y; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China; Department of Thoracic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210009, PR China.
Su C; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Che Y; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, PR China.
Xu J; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Sun K; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Ni J; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Huang L; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Shen Y; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, PR China.
Jia L; Department of Pathology, Affiliated Cancer Hospital of Nanjing Medical University and Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, PR China.
Xu L; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China.
Yin R; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; Department of Scientific Research, Jiangsu Cancer Hospital & the Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China. Electronic address: rong_.
Li M; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China. Electronic address: .
Hu J; Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, Jiangsu, 210009, PR China; The Fourth Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210009, PR China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216426. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Small Cell Lung Carcinoma*/genetics
Lung Neoplasms*/metabolism
RNA, Long Noncoding*/genetics
Humans ; Cell Line, Tumor ; DEAD-box RNA Helicases/genetics ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Gene Expression Regulation, Neoplastic ; Cell Proliferation/genetics ; Cell Movement ; Neoplasm Metastasis ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism
Czasopismo naukowe
Tytuł:
LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein.
Autorzy:
Hua H; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China.
Su T; Shandong University Cancer Center, Jinan, Shandong Province, 250117, China.
Han L; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China.
Zhang L; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China.
Huang Y; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China.
Zhang N; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu Province, China. Electronic address: .
Yang M; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China; Shandong University Cancer Center, Jinan, Shandong Province, 250117, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu Province, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216436. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stomach Neoplasms*/pathology
RNA, Long Noncoding*/genetics
Humans ; beta Catenin/genetics ; beta Catenin/metabolism ; Catenins/genetics ; Catenins/metabolism ; Wnt Signaling Pathway/genetics ; Cell Proliferation/genetics ; Cytoplasm/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism
Czasopismo naukowe
Tytuł:
LW-213 induces immunogenic tumor cell death via ER stress mediated by lysosomal TRPML1.
Autorzy:
Zhu MY; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Wang T; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Wang HD; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Wang HZ; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Chen HY; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Zhang S; The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Guo YJ; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China.
Li H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China. Electronic address: gj_.
Hui H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People's Republic of China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216435. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Neoplasms*/metabolism
Humans ; Mice ; Animals ; Immunogenic Cell Death ; Mice, Inbred C57BL ; Endoplasmic Reticulum Stress ; Lysosomes/metabolism ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Autorzy:
Zhou Y; Faculty of Health Sciences, University of Macau, Taipa, Macau.
Guo Y; Faculty of Health Sciences, University of Macau, Taipa, Macau.
Ran M; Faculty of Health Sciences, University of Macau, Taipa, Macau.
Shan W; Faculty of Health Sciences, University of Macau, Taipa, Macau.
Granchi C; Dipartimento di Farmacia, Università di Pisa, 56126, Pisa, Italy.
Giovannetti E; Department of Medical Oncology, Amsterdam University Medical Centers, Location VUmc, Cancer Center Amsterdam, 1081, HV Amsterdam, the Netherlands; Fondazione Pisana per La Scienza, Pisa, Italy.
Minutolo F; Dipartimento di Farmacia, Università di Pisa, 56126, Pisa, Italy.
Peters GJ; Department of Biochemistry, Medical University of Gdansk, 80-210, Gdańsk, Poland; Department of Medical Oncology, Amsterdam University Medical Centers, Location VUmc, Cancer Center Amsterdam, 1081, HV Amsterdam, the Netherlands.
Tam KY; Faculty of Health Sciences, University of Macau, Taipa, Macau. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216425. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Adenocarcinoma of Lung*/drug therapy
Humans ; Lactate Dehydrogenase 5/metabolism ; Lactate Dehydrogenase 5/pharmacology ; Pyruvate Dehydrogenase Acetyl-Transferring Kinase/metabolism ; Cell Line, Tumor ; Signal Transduction ; Glycolysis ; Cell Death ; Cell Proliferation ; L-Lactate Dehydrogenase
Czasopismo naukowe
Tytuł:
SYT7 is a key player in increasing exosome secretion and promoting angiogenesis in non-small-cell lung cancer.
Autorzy:
Liu X; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China.
Li R; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China.
Chen X; Department of Respiratory Medicine, Tai'an City Central Hospital, Tai'an, China.
Yao J; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China.
Wang Q; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China.
Zhang J; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China.
Jiang Y; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China. Electronic address: .
Qu Y; Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China. Electronic address: .
Pokaż więcej
Źródło:
Cancer letters [Cancer Lett] 2023 Nov 28; Vol. 577, pp. 216400. Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/metabolism
Exosomes*/metabolism
Humans ; Synaptotagmins/genetics ; Synaptotagmins/metabolism ; Endothelial Cells/metabolism ; Cell Line, Tumor ; Cell Proliferation
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies