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Wyszukujesz frazę ""Cell Movement drug effects"" wg kryterium: Temat


Tytuł :
Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma:Increased Cell Migration and Its Association with EGFR Expression
Autorzy :
Molnár, Eszter
Garay, Tamás
Donia, Marco
Baranyi, Marcell
Rittler, Dominika
Berger, Walter
Tímár, József
Grusch, Michael
Hegedűs, Balázs
Pokaż więcej
Temat :
Adult
Aged
Cell Line, Tumor
Cell Movement/drug effects
Cell Proliferation/drug effects
Drug Resistance, Neoplasm/drug effects
Epithelial-Mesenchymal Transition/drug effects
ErbB Receptors/metabolism
Erlotinib Hydrochloride/pharmacology
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Inhibitory Concentration 50
Male
Melanoma/drug therapy
Middle Aged
Mutation/genetics
Neoplasm Proteins/genetics
Phenotype
Proto-Oncogene Proteins B-raf/genetics
RNA, Messenger/genetics
Signal Transduction/drug effects
Time Factors
Vemurafenib/pharmacology
Journal Article
Źródło :
Molnár, E, Garay, T, Donia, M, Baranyi, M, Rittler, D, Berger, W, Tímár, J, Grusch, M & Hegedűs, B 2019, ' Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma : Increased Cell Migration and Its Association with EGFR Expression ', International Journal of Molecular Sciences, vol. 20, no. 18, 4484 . https://doi.org/10.3390/ijms20184484
Opis pliku :
application/pdf
Tytuł :
CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma
Autorzy :
Neu, Johannes
Dziunycz, Piotr J.
Lefort, Karine
Djerbi, Nadia
Freiberger, Sandra N.
Iotzova-Weiss, Guergana
French, Lars E.
Dotto, Gian-Paolo
Hofbauer, Günther F.
Pokaż więcej
Temat :
biological phenomena, cell phenomena, and immunity
Notch Signaling
610 Medicine & health
Oncology
hemic and lymphatic diseases
Carcinomas
Molecular Biology Techniques
Differentiated Tumors
Protein Expression
Epidermis
Cellular Types
cardiovascular system
Biology and Life Sciences
RNA
Signal Transduction
Animal Cells
Keratinocytes
Nucleic acids
Small interfering RNAs
Gene regulation
Science
Epithelium
Gene expression
Molecular Biology
Adaptor Proteins, Signal Transducing/antagonists & inhibitors
Adaptor Proteins, Signal Transducing/genetics
Adaptor Proteins, Signal Transducing/metabolism
Carcinoma, Squamous Cell/genetics
Carcinoma, Squamous Cell/metabolism
Carcinoma, Squamous Cell/physiopathology
Cell Differentiation
Cell Line
Cell Movement/drug effects
Chromatin Immunoprecipitation
Down-Regulation
Humans
Keratinocytes/cytology
Keratinocytes/metabolism
Promoter Regions, Genetic
Protein Binding
RNA Interference
RNA, Small Interfering/metabolism
Receptor, Notch1/metabolism
Signal Transduction/drug effects
Skin Neoplasms/genetics
Skin Neoplasms/metabolism
Skin Neoplasms/physiopathology
Tamoxifen/pharmacology
Transcription Factor HES-1/metabolism
Research Article
Molecular Biology Assays and Analysis Techniques
Gene Expression and Vector Techniques
Anatomy
Skin
Genetics
Biological Tissue
embryonic structures
Cancers and Neoplasms
Non-coding RNA
Developmental Biology
Dermatology Clinic
Research and Analysis Methods
sense organs
Epithelial Cells
Squamous Cell Carcinomas
Integumentary System
Medicine
Cell Biology
Cell Signaling
Biochemistry
Medicine and Health Sciences
Źródło :
Dziunycz, Piotr J; Neu, Johannes; Lefort, Karine; Djerbi, Nadia; Freiberger, Sandra N; Iotzova-Weiss, Guergana; French, Lars E; Dotto, Gian-Paolo; Hofbauer, Günther F (2017). CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma. PLoS ONE, 12(4):e0173000.
PLoS ONE, Vol 12, Iss 4, p e0173000 (2017)
PLoS One, vol. 12, no. 4, pp. e0173000
Opis pliku :
application/pdf
Tytuł :
A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
Autorzy :
Claudio Raimondi
Veronique Calleja
Riccardo Ferro
Alessandro Fantin
Andrew M. Riley
Barry V. L. Potter
Caroline H. Brennan
Tania Maffucci
Banafshé Larijani
Marco Falasca
Pokaż więcej
Temat :
Phospholipase C gamma/antagonists & inhibitors
Heterografts
Protein Multimerization
Antineoplastic Agents/pharmacology
animal structures
Breast Neoplasms/drug therapy
Protein-Serine-Threonine Kinases/antagonists & inhibitors
Protein Binding
Cell Movement/drug effects
Neoplasm Transplantation
Article
Disease Models, Animal
Enzyme Inhibitors/pharmacology
Animals
Inositol Phosphates/pharmacology
Melanoma/drug therapy
Zebrafish
Cell Line
Humans
Źródło :
Raimondi, C, Calleja, V, Ferro, R, Fantin, A, Riley, A M, Potter, B V L, Brennan, C H, Maffucci, T, Larijani, B & Falasca, M 2016, ' A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion ', Scientific Reports, vol. 6, 26142 . https://doi.org/10.1038/srep26142
Scientific Reports, 6, Article 26142. (2016)
Opis pliku :
text; application/pdf
Tytuł :
Knockout of the PKN family of Rho effector kinases reveals a non-redundant role for PKN2 in developmental mesoderm expansion
Autorzy :
Quétier, I.
Marshall, J. J.
Spencer-Dene, B.
Lachmann, S.
Casamassima, A.
Franco, C.
Escuin, S.
Worrall, J. T.
Baskaran, P.
Rajeeve, V.
Howell, M.
Copp, A. J.
Stamp, G.
Rosewell, I.
Cutillas, P.
Gerhardt, H.
Parker, P. J.
Cameron, A. J.
Pokaż więcej
Temat :
4-hydroxytamoxifen
Protein Kinase C/deficiency
Embryonic stem cells
PKC
Microscopy, Electron, Scanning
Embryonic Development/drug effects
Heart/growth & development
Mice
Mice, Knockout
Cell Movement/drug effects
MEF
Apoptosis/drug effects
4-OHT
Mesoderm/cytology
PKN
Mice, Inbred C57BL
4-OHT, 4-hydroxytamoxifen, ES cells, Embryonic stem cells, MEF, NCCs, PKC, PKN, Protein kinase N, mouse embryonic fibroblasts, neural crest cells, protein kinase C
embryonic structures
NCCs
mouse embryonic fibroblasts
Animals
Cell Line
ES cells
Cell Proliferation/drug effects
Embryo, Mammalian/cytology
Tamoxifen/analogs & derivatives
Antineoplastic Agents/pharmacology
animal structures
QH301-705.5
neural crest cells
Cardiovascular and Metabolic Diseases
Protein kinase N
Genes, Reporter
Myocardium/metabolism
Report
protein kinase C
Biology (General)
Źródło :
Quétier, I, Marshall, J J T, Spencer-Dene, B, Lachmann, S, Casamassima, A, Franco, C, Escuin, S, Worrall, J T, Baskaran, P, Rajeeve, V, Howell, M, Copp, A J, Stamp, G, Rosewell, I, Cutillas, P, Gerhardt, H, Parker, P J & Cameron, A J M 2016, ' Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion ', Cell Reports, vol. 14, no. 3, pp. 440-448 . https://doi.org/10.1016/j.celrep.2015.12.049
Cell Reports, Vol 14, Iss 3, Pp 440-448 (2016)
Cell Reports, 14 (3) pp. 440-448. (2016)
Opis pliku :
text; application/pdf
Tytuł :
MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation
Autorzy :
Schlosser, Anders
Pilecki, Bartosz
Hemstra, Line E
Kejling, Karin
Kristmannsdottir, Gudlaug B
Wulf-Johansson, Helle
Moeller, Jesper B
Füchtbauer, Ernst-Martin
Nielsen, Ole
Kirketerp-Møller, Katrine
Dubey, Lalit K
Hansen, Pernille B L
Stubbe, Jane
Wrede, Christoph
Hegermann, Jan
Ochs, Matthias
Rathkolb, Birgit
Schrewe, Anja
Bekeredjian, Raffi
Wolf, Eckhard
Gailus-Durner, Valérie
Fuchs, Helmut
de Angelis, Martin Hrabě
Lindholt, Jes S
Holmskov, Uffe
Sorensen, Grith L
Pokaż więcej
Temat :
MFAP4 protein
carotid stenosis
extracellular matrix proteins
hyperplasia
integrin alphaVbeta3
mouse
muscle
smooth
vascular
Chemotaxis, Leukocyte
Focal Adhesion Kinase 1/antagonists & inhibitors
Phosphorylation
Vascular Remodeling
Cell Movement/drug effects
Humans
Hyperplasia
Male
Neointima
Time Factors
Cell Proliferation/drug effects
Disease Models, Animal
Carotid Arteries/metabolism
Signal Transduction
Integrin alphaVbeta3/metabolism
Mice, Inbred C57BL
Cells, Cultured
Carotid Artery Diseases/genetics
Extracellular Matrix Proteins/deficiency
Genotype
Glycoproteins/deficiency
Myocytes, Smooth Muscle/drug effects
Muscle, Smooth, Vascular/drug effects
Mice, Knockout
Phenotype
Animals
Carrier Proteins/genetics
Ligands
Mice, Inbred BALB C
Protein Kinase Inhibitors/pharmacology
Apoptosis
Monocytes/metabolism
Źródło :
Schlosser, A, Pilecki, B, Hemstra, L E, Kejling, K, Kristmannsdottir, G B, Wulf-Johansson, H, Moeller, J B, Füchtbauer, E-M, Nielsen, O, Kirketerp-Møller, K, Dubey, L K, Hansen, P B L, Stubbe, J, Wrede, C, Hegermann, J, Ochs, M, Rathkolb, B, Schrewe, A, Bekeredjian, R, Wolf, E, Gailus-Durner, V, Fuchs, H, de Angelis, M H, Lindholt, J S, Holmskov, U & Sorensen, G L 2016, ' MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, no. 1, pp. 122-133 . https://doi.org/10.1161/ATVBAHA.115.306672

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