Temat: "Cell Survival" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Long Noncoding RNA LINC01347 Modulated Lidocaine-Induced Cytotoxicity in SH-SY5Y Cells by Interacting with hsa-miR-145-5p.
Autorzy:: Zhang Y; Department of Anesthesiology, Huangdao District Central Hospital, Qingdao, 266500, Shandong Province, China.
Liu L; Changjiang Road Community Health Service Center, Huangdao District, Qingdao, 266500, Shandong Province, China.
Xue P; Department of Anesthesiology, Huangdao District Central Hospital, Qingdao, 266500, Shandong Province, China.
Wang L; Department of Anesthesiology, Huangdao District Central Hospital, Qingdao, 266500, Shandong Province, China. lily_.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1440-1448. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji:: Journal Article
MeSH Terms:: Anesthetics, Local/*toxicity
Cell Survival/*drug effects
Lidocaine/*toxicity
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Cell Line, Tumor ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Humans

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Skocz do pozycji: 2.

Tytuł:: COA-Cl Evokes Protective Responses Against H 2 O 2 -and 6-OHDA-Induced Toxic Injury in PC12 Cells.
Autorzy:: Jamal M; Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki, Kita, Kagawa, 761-0793, Japan. .
Tsukamoto I; Department of Pharmaco-Bio-Informatics, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Maki T; Department of Pharmaco-Bio-Informatics, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Takei S; Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki, Kita, Kagawa, 761-0793, Japan.
Konishi R; Department of Pharmaco-Bio-Informatics, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Kinoshita H; Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki, Kita, Kagawa, 761-0793, Japan.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Dec; Vol. 40 (6), pp. 2061-2071. Date of Electronic Publication: 2022 Nov 26.
Typ publikacji:: Journal Article
MeSH Terms:: Hydrogen Peroxide*/toxicity
Neuroprotective Agents*/pharmacology
Rats ; Animals ; Oxidopamine/toxicity ; PC12 Cells ; Oxidative Stress ; Antioxidants/pharmacology ; bcl-2-Associated X Protein ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Cell Survival

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Skocz do pozycji: 3.

Tytuł:: Citronellol Prevents 6-OHDA-Induced Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Parkinson Disease Model of SH-SY5Y Cells via Modulating ROS-NO, MAPK/ERK, and PI3K/Akt Signaling Pathways.
Autorzy:: Shao J; Department of Neurology, The First People's Hospital of Wenling, Zhejiang Province, Wenling, 317500, China.
Liu X; Department of Neurology, The First People's Hospital of Wenling, Zhejiang Province, Wenling, 317500, China.
Lian M; Department of Neurology, The First People's Hospital of Wenling, Zhejiang Province, Wenling, 317500, China.
Mao Y; Department of Special Inspection Section, The First People's Hospital of Wenling, No. 333, Chuanan South Road, Chengxi StreetZhejiang Province, Wenling, 317500, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Dec; Vol. 40 (6), pp. 2221-2237. Date of Electronic Publication: 2022 Sep 12.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/drug therapy
Parkinson Disease*/metabolism
Neuroblastoma*/metabolism
Humans ; Reactive Oxygen Species/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Oxidopamine/toxicity ; Oxidopamine/metabolism ; Cell Line, Tumor ; Apoptosis ; Signal Transduction ; Oxidative Stress ; Mitochondria ; Cell Survival

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Skocz do pozycji: 4.

Tytuł:: Neonatal Isoflurane Exposure in Rats Impairs Short-Term Memory, Cell Viability, and Glutamate Uptake in Slices of the Frontal Cerebral Cortex, But Not the Hippocampus, in Adulthood.
Autorzy:: de Oliveira LF; Instituto de Farmacologia e Terapêuticas Experimentais, Universidade de Coimbra, 3005-504, Coimbra, Portugal.; Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (ICBR), Universidade de Coimbra, 30050504, Coimbra, Portugal.
Poluceno GG; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Sampaio TB; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88049-900, Brazil.
Constantino LC; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Costa AP; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Martins WC; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Dal-Cim T; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
de Oliveira KA; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Ludka FK; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil.
Prediger RD; Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88049-900, Brazil.
Pereira FC; Instituto de Farmacologia e Terapêuticas Experimentais, Universidade de Coimbra, 3005-504, Coimbra, Portugal. .; Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (ICBR), Universidade de Coimbra, 30050504, Coimbra, Portugal. .; Center for Innovative Biomedicine and Biotechnology (CIBB), Universidade de Coimbra, 3004-504, Coimbra, Portugal. .
Tasca CI; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianopolis, SC, 88040-900, Brazil. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Dec; Vol. 40 (6), pp. 1924-1936. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:: Journal Article
MeSH Terms:: Isoflurane*/toxicity
Anesthetics*
Anesthetics, Inhalation*/toxicity
Rats ; Animals ; Glutamic Acid/metabolism ; Memory, Short-Term ; Cell Survival ; Hippocampus ; Frontal Lobe/metabolism ; Cerebral Cortex/metabolism

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Skocz do pozycji: 5.

Tytuł:: Endocrine resistant breast cancer cells with loss of ERα expression retain proliferative ability by reducing caspase7-mediated HDAC3 cleavage.
Autorzy:: Yu S; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Gong X; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Ma Z; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Zhang M; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Huang L; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Zhang J; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Zhao S; Department of Medical Oncology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, People's Republic of China.
Zhu T; Institute of Immunology and CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Biology, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, 230027, People's Republic of China.
Yu Z; Department of Medical Oncology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, People's Republic of China. .
Chen L; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, 210023, People's Republic of China.; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2020 Feb; Vol. 43 (1), pp. 65-80. Date of Electronic Publication: 2019 Nov 07.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Proliferation*/drug effects
Cell Proliferation*/genetics
Breast Neoplasms/*metabolism
Caspase 7/*metabolism
Cell Survival/*genetics
Drug Resistance, Neoplasm/*genetics
Estrogen Receptor alpha/*metabolism
Histone Deacetylases/*metabolism
Acetylation ; Breast Neoplasms/enzymology ; Breast Neoplasms/genetics ; Caspase 7/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Estrogen Receptor alpha/genetics ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/genetics ; Histone Deacetylase Inhibitors/pharmacology ; Histones/metabolism ; Humans ; Immunohistochemistry ; RNA Interference ; Tamoxifen/pharmacology

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Skocz do pozycji: 6.

Tytuł:: A Cannabinoid Receptor-Mediated Mechanism Participates in the Neuroprotective Effects of Oleamide Against Excitotoxic Damage in Rat Brain Synaptosomes and Cortical Slices.
Autorzy:: Maya-López M; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.
Rubio-López LC; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.; Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rodríguez-Alvarez IV; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.; Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico.
Orduño-Piceno J; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.; Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico.
Flores-Valdivia Y; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.; Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Colonnello A; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.; Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Rangel-López E; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.
Túnez I; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina y Enfermería, Universidad de Córdoba, Cordoba, Spain.; Instituto Maimonides de Investigación Biomédica de Códoba (IMIBIC) & Red Española de Excelencia de Estimulación Cerebral (REDESTIM), Cordoba, Spain.
Prospéro-García O; Laboratorio de Cannabinoides, Departamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Santamaría A; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2020 Jan; Vol. 37 (1), pp. 126-135. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Survival/*physiology
Cerebral Cortex/*drug effects
Neuroprotective Agents/*pharmacology
Oleic Acids/*pharmacology
Receptor, Cannabinoid, CB1/*physiology
Receptor, Cannabinoid, CB2/*physiology
Synaptosomes/*drug effects
Synaptosomes/*physiology
Animals ; Brain/drug effects ; Cell Survival/drug effects ; Lipid Peroxidation/drug effects ; Male ; Morpholines/pharmacology ; Oleic Acids/antagonists & inhibitors ; Pyrazoles/pharmacology ; Quinolinic Acid/antagonists & inhibitors ; Quinolinic Acid/toxicity ; Rats ; Receptor, Cannabinoid, CB1/agonists ; Receptor, Cannabinoid, CB2/agonists

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Skocz do pozycji: 7.

Tytuł:: In vitro Evaluation of Selective Cytotoxic Activity of Chaerophyllum macropodum Boiss. on Cultured Human SH-SY5Y Neuroblastoma Cells.
Autorzy:: Çelikezen FÇ; Department of Chemistry, Faculty of Science and Letter, Bitlis Eren University, Bitlis, Turkey. .
Türkez H; Department of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Firat M; Department of Biology, Faculty of Education, Van Yuzuncu Yil University, Van, Turkey.
Arslan ME; Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Öner S; Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Oct; Vol. 40 (5), pp. 1360-1368. Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neuroblastoma*/pathology
Bromides/pharmacology ; Bromides/therapeutic use ; Cell Line, Tumor ; Cell Survival ; Child ; Coumaric Acids/therapeutic use ; Humans ; Lactate Dehydrogenases ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Salicylic Acid/pharmacology ; Salicylic Acid/therapeutic use

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Skocz do pozycji: 8.

Tytuł:: Silver Nanoparticles Induce a Size-dependent Neurotoxicity to SH-SY5Y Neuroblastoma Cells via Ferritinophagy-mediated Oxidative Stress.
Autorzy:: Zhai X; School of Public Health, Suzhou Medical College of Soochow University, 199 Renai Road, Suzhou, Jiangsu, 215123, China.
Shan S; School of Public Health, Suzhou Medical College of Soochow University, 199 Renai Road, Suzhou, Jiangsu, 215123, China.
Wan J; Suzhou Medical College of Soochow University, 199 Renai Road, Suzhou, Jiangsu, 215123, China.
Tian H; School of Public Health, Suzhou Medical College of Soochow University, 199 Renai Road, Suzhou, Jiangsu, 215123, China.
Wang J; Suzhou Center for Disease Prevention and Control, 72 Sanxiang Road, Suzhou, Jiangsu, 215004, China. .
Xin L; School of Public Health, Suzhou Medical College of Soochow University, 199 Renai Road, Suzhou, Jiangsu, 215123, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Oct; Vol. 40 (5), pp. 1369-1379. Date of Electronic Publication: 2022 Aug 30.
Typ publikacji:: Journal Article
MeSH Terms:: Metal Nanoparticles*/toxicity
Neuroblastoma*
Neurotoxicity Syndromes*
Amyloid Precursor Protein Secretases ; Amyloid beta-Protein Precursor/metabolism ; Anti-Bacterial Agents/pharmacology ; Antifungal Agents/pharmacology ; Antioxidants/pharmacology ; Aspartic Acid Endopeptidases ; Cell Line, Tumor ; Cell Survival ; Humans ; Iron/metabolism ; Iron/toxicity ; Malondialdehyde/metabolism ; Nuclear Receptor Coactivators/metabolism ; Oxidants/pharmacology ; Oxidative Stress ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Silver/toxicity

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Skocz do pozycji: 9.

Tytuł:: A Pretreatment with Isoorientin Attenuates Redox Disruption, Mitochondrial Impairment, and Inflammation Caused by Chlorpyrifos in a Dopaminergic Cell Line: Involvement of the Nrf2/HO-1 Axis.
Autorzy:: Brasil FB; Departamento de Ciências da Natureza, Campus Universitário de Rio das Ostras - Universidade Federal Fluminense (UFF), Rio de Janeiro, Brazil.
de Almeida FJS; Programa de Pós-Graduação Em Ciências da Saúde (PPGCS), Universidade Federal de Mato Grosso (UFMT), Cuiaba, Mato Grosso, Brazil.; Grupo de Estudos Em Neuroquímica E Neurobiologia de Moléculas Bioativas, Departamento de Química, Universidade Federal de Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, Mato Grosso, CEP 78060-900, Brazil.
Luckachaki MD; Grupo de Estudos Em Neuroquímica E Neurobiologia de Moléculas Bioativas, Departamento de Química, Universidade Federal de Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, Mato Grosso, CEP 78060-900, Brazil.
Dall'Oglio EL; Grupo de Estudos Em Neuroquímica E Neurobiologia de Moléculas Bioativas, Departamento de Química, Universidade Federal de Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, Mato Grosso, CEP 78060-900, Brazil.
de Oliveira MR; Grupo de Estudos Em Neuroquímica E Neurobiologia de Moléculas Bioativas, Departamento de Química, Universidade Federal de Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, Mato Grosso, CEP 78060-900, Brazil. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Aug; Vol. 40 (4), pp. 1043-1056. Date of Electronic Publication: 2022 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: Chlorpyrifos*/toxicity
Neuroblastoma*/metabolism
Cell Line, Tumor ; Cell Survival ; Heme Oxygenase-1/metabolism ; Humans ; Inflammation/metabolism ; Luteolin/metabolism ; Luteolin/pharmacology ; Mitochondria ; NF-E2-Related Factor 2/metabolism ; Oxidation-Reduction

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Skocz do pozycji: 10.

Tytuł:: The Impact of the Antipsychotic Medication Chlorpromazine on Cytotoxicity through Ca Signaling Pathway in Glial Cell Models.
Autorzy:: Chu CS; Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan.
Lin YS; Department of Neurosurgery, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan.
Liang WZ; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan. .; Department of Pharmacy and Master Program, College of Pharmacy and Health Care, Tajen University, Pingtung County, 90741, Taiwan. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Jun; Vol. 40 (3), pp. 791-802. Date of Electronic Publication: 2022 Apr 19.
Typ publikacji:: Journal Article
MeSH Terms:: Antipsychotic Agents*/toxicity
Calcium Signaling*
Apoptosis ; Calcium/metabolism ; Cell Line, Tumor ; Cell Survival ; Chelating Agents ; Chlorpromazine/pharmacology ; Humans ; Neuroglia/metabolism ; Thapsigargin/pharmacology ; Type C Phospholipases/metabolism ; Type C Phospholipases/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling.
Autorzy:: Bernhard SV; Molecular Genetics, TU Kaiserslautern, Paul-Ehrlich-Strasse 24, 67663, Kaiserslautern, Germany.
Seget-Trzensiok K; Molecular Genetics, TU Kaiserslautern, Paul-Ehrlich-Strasse 24, 67663, Kaiserslautern, Germany.
Kuffer C; Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152, Martinsried, Germany.
Krastev DB; National Center for Tumor Diseases (NCT): German Cancer Research Center (DKFZ) Heidelberg, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Fetscherstraße 74/PF 64, 01307, Dresden, Germany.
Stautmeister LM; Molecular Genetics, TU Kaiserslautern, Paul-Ehrlich-Strasse 24, 67663, Kaiserslautern, Germany.
Theis M; National Center for Tumor Diseases (NCT): German Cancer Research Center (DKFZ) Heidelberg, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Fetscherstraße 74/PF 64, 01307, Dresden, Germany.; Medical Systems Biology, Medical Faculty and University Hospital Carl Gustav Carus, TU Dresden, 01307, Dresden, Germany.
Keuper K; Molecular Genetics, TU Kaiserslautern, Paul-Ehrlich-Strasse 24, 67663, Kaiserslautern, Germany.
Boekenkamp JE; Koblenz University of Applied Sciences, Joseph-Rovan-Allee 2, Remagen, Germany.
Kschischo M; Koblenz University of Applied Sciences, Joseph-Rovan-Allee 2, Remagen, Germany.
Buchholz F; National Center for Tumor Diseases (NCT): German Cancer Research Center (DKFZ) Heidelberg, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Fetscherstraße 74/PF 64, 01307, Dresden, Germany.; Medical Systems Biology, Medical Faculty and University Hospital Carl Gustav Carus, TU Dresden, 01307, Dresden, Germany.; German Cancer Research Center (DKFZ), Heidelberg and German Cancer Consortium (DKTK) Partner Site, Dresden, Germany.
Storchova Z; Molecular Genetics, TU Kaiserslautern, Paul-Ehrlich-Strasse 24, 67663, Kaiserslautern, Germany. .; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2022 Feb; Vol. 45 (1), pp. 103-119. Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: Membrane Glycoproteins*/genetics
Neoplasms*
Ubiquitin Thiolesterase*/genetics
Ubiquitin Thiolesterase*/metabolism
Cell Cycle Checkpoints/genetics ; Cell Survival/genetics ; HCT116 Cells ; Humans ; Tetraploidy ; Tumor Suppressor Protein p53/metabolism

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Skocz do pozycji: 12.

Tytuł:: SIRT1 Protects Dopaminergic Neurons in Parkinson's Disease Models via PGC-1α-Mediated Mitochondrial Biogenesis.
Autorzy:: Chen Y; Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Jiang Y; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, 19 Qixiu Road, Nantong, China.
Yang Y; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, 19 Qixiu Road, Nantong, China.
Huang X; Department of Nephrology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001, Jiangsu, China.
Sun C; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, 19 Qixiu Road, Nantong, China. .; Nantong Key Laboratory of Translational Medicine in Cardiothoracic Diseases, Institute of Translational Medicine in Cardiothoracic Diseases, Affiliated Hospital of Nantong University, 20 Xishi Road, Nantong, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1393-1404. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Organelle Biogenesis*
Dopaminergic Neurons/*metabolism
Mitochondria/*metabolism
Parkinsonian Disorders/*metabolism
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*biosynthesis
Sirtuin 1/*biosynthesis
1-Methyl-4-phenylpyridinium/toxicity ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/pathology ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Membrane Potential, Mitochondrial/physiology ; Mitochondria/drug effects ; Mitochondria/pathology ; Neuroprotection/drug effects ; Neuroprotection/physiology ; Parkinsonian Disorders/chemically induced ; Parkinsonian Disorders/genetics ; Parkinsonian Disorders/prevention & control ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Sirtuin 1/genetics

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Skocz do pozycji: 13.

Tytuł:: Tris (2,3-Dibromopropyl) Isocyanurate (TDBP-TAZTO or TBC) Shows Different Toxicity Depending on the Degree of Differentiation of the Human Neuroblastoma (SH-SY5Y) Cell Line.
Autorzy:: Szychowski KA; Department of Biotechnology and Cell Biology, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225, Rzeszow, Poland. .
Skóra B; Department of Biotechnology and Cell Biology, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225, Rzeszow, Poland.
Mańdziuk M; Department of Physiotherapy, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225, Rzeszow, Poland.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1575-1588. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Differentiation/*drug effects
Flame Retardants/*toxicity
Neuroblastoma/*metabolism
Neuroblastoma/*pathology
Organophosphates/*toxicity
Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Differentiation/physiology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Humans ; Reactive Oxygen Species/metabolism ; Receptors, Aryl Hydrocarbon/metabolism

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Skocz do pozycji: 14.

Tytuł:: Suppression of Mitochondria-Related Bioenergetics Collapse and Redox Impairment by Tanshinone I, a Diterpenoid Found in Salvia miltiorrhiza Bunge (Danshen), in the Human Dopaminergic SH-SY5Y Cell Line Exposed to Chlorpyrifos.
Autorzy:: Brasil FB; Department of Natural Sciences, Rio das Ostras Universitary Campus - Fluminense Federal University (UFF), Rio de Janeiro, Brazil.
de Almeida FJS; Graduate Program in Health Sciences (PPGCS), Federal University of Mato Grosso (UFMT), Cuiaba, MT, Brazil.; Research Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil.
Luckachaki MD; Research Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil.
Dall'Oglio EL; Research Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil.
de Oliveira MR; Research Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1495-1510. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji:: Journal Article
MeSH Terms:: Salvia miltiorrhiza*
Abietanes/*pharmacology
Chlorpyrifos/*toxicity
Dopaminergic Neurons/*drug effects
Energy Metabolism/*drug effects
Mitochondria/*drug effects
Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Dopaminergic Neurons/metabolism ; Dose-Response Relationship, Drug ; Energy Metabolism/physiology ; Humans ; Immunosuppressive Agents/pharmacology ; Insecticides/toxicity ; Mitochondria/metabolism ; Oxidation-Reduction/drug effects

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Tytuł:: The Protective Effects of Benzbromarone Against Propofol-Induced Inflammation and Injury in Human Brain Microvascular Endothelial Cells (HBMVECs).
Autorzy:: Huang Z; Department of Anesthesiology, Affiliated Hospital of Youjiang Medical University, Baise City, Guangxi, 533000, China.
Huang B; Department of Anesthesiology, People's Hospital of Tiandong, Baise City, Guangxi, 533000, China.
Wei Q; Department of Anesthesiology, People's Hospital of Baise, Baise City, Guangxi, 533000, China.
Su X; Department of Anesthesiology, People's Hospital of Baise, Baise City, Guangxi, 533000, China.
Li X; Department of Anesthesiology, People's Hospital of Baise, Baise City, Guangxi, 533000, China.
Qin S; Department of Anesthesiology, People's Hospital of Baise, Baise City, Guangxi, 533000, China.
Huang W; Department of Anesthesiology, People's Hospital of Baise, Baise City, Guangxi, 533000, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1449-1458. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji:: Journal Article
MeSH Terms:: Benzbromarone/*pharmacology
Brain/*drug effects
Endothelial Cells/*drug effects
Microvessels/*drug effects
Neuroprotective Agents/*pharmacology
Propofol/*toxicity
Anesthetics, Intravenous/toxicity ; Blood-Brain Barrier/cytology ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/pathology ; Brain/cytology ; Brain/pathology ; Cell Survival/drug effects ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Endothelial Cells/pathology ; Humans ; Microvessels/cytology ; Microvessels/pathology

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Tytuł:: Bone Marrow Mesenchymal Stem Cell Condition Medium Loaded on PCL Nanofibrous Scaffold Promoted Nerve Regeneration After Sciatic Nerve Transection in Male Rats.
Autorzy:: Raoofi A; Leishmaniasis Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.; Department of Anatomy, Sabzevar University of Medical Sciences, Sabzevar, Iran.; Hearing Disorders Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sadeghi Y; Department of Anatomy and Neuroscience, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Melbourne, VIC, Australia.
Piryaei A; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sajadi E; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aliaghaei A; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rashidiani-Rashidabadi A; Department of Anatomical Sciences, Lorestan University of Medical Sciences, Khorramabad, Iran.
Fatabadi FF; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahdavi B; Department of Chemistry, Faculty of Science, Hakim Sabzevari University, Sabzevar, Iran.
Abdollahifar MA; Hearing Disorders Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. m_.; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. m_.
Khaneghah AM; Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Oct; Vol. 39 (5), pp. 1470-1486. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji:: Journal Article
MeSH Terms:: Culture Media, Conditioned/*pharmacology
Mesenchymal Stem Cells/*physiology
Nanofibers/*administration & dosage
Nerve Regeneration/*physiology
Polyesters/*administration & dosage
Sciatic Neuropathy/*therapy
Animals ; Cell Line ; Cell Survival/drug effects ; Cell Survival/physiology ; Male ; Mice ; Nerve Regeneration/drug effects ; Rats ; Rats, Wistar ; Sciatic Nerve/drug effects ; Sciatic Nerve/pathology ; Sciatic Nerve/physiology ; Sciatic Neuropathy/pathology ; Tissue Scaffolds

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Skocz do pozycji: 17.

Tytuł:: Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia.
Autorzy:: Lipreri da Silva JC; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Coelho-Silva JL; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Lima K; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Vicari HP; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Lazarini M; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema, Brazil.
Costa-Lotufo LV; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil.
Traina F; Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Machado-Neto JA; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524, CEP 05508-900, São Paulo, SP, Brazil. .; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Oct; Vol. 44 (5), pp. 1105-1117. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Leukemic*
Biomarkers, Tumor/*genetics
Cytoskeletal Proteins/*genetics
Cytoskeleton/*metabolism
Genes, Regulator/*genetics
Leukemia, Myeloid/*genetics
Acute Disease ; Adamantane/analogs & derivatives ; Adamantane/pharmacology ; Adult ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cytoskeletal Proteins/antagonists & inhibitors ; Cytoskeletal Proteins/metabolism ; Disease-Free Survival ; Female ; HL-60 Cells ; Humans ; K562 Cells ; Leukemia, Myeloid/diagnosis ; Leukemia, Myeloid/metabolism ; Male ; Phenols/pharmacology ; Prognosis ; Quinolines/pharmacology ; Quinolones/pharmacology ; THP-1 Cells ; U937 Cells

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Skocz do pozycji: 18.

Tytuł:: CDK7 blockade suppresses super-enhancer-associated oncogenes in bladder cancer.
Autorzy:: Yang Y; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Jiang D; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Zhou Z; Urology Institute of Shenzhen University, The Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China.; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China.
Xiong H; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Yang X; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Peng G; Urology Institute of Shenzhen University, The Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China.; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China.
Xia W; Urology Institute of Shenzhen University, The Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China.; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China.
Wang S; Urology Institute of Shenzhen University, The Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China.; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China.
Lei H; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Zhao J; Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Qian Z; Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
Wu S; Urology Institute of Shenzhen University, The Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, 518000, China. .; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen, 518000, China. .
Pang J; Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China. .; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Aug; Vol. 44 (4), pp. 871-887. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclin-Dependent Kinases/*antagonists & inhibitors
Enhancer Elements, Genetic/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Oncogenes/*genetics
Phenylenediamines/*pharmacology
Pyrimidines/*pharmacology
Urinary Bladder Neoplasms/*genetics
Animals ; Antibiotics, Antineoplastic/pharmacology ; Apoptosis/drug effects ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; Drug Synergism ; Female ; Humans ; Mice, Nude ; RNA-Seq/methods ; Sirolimus/pharmacology ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Tumor Burden/drug effects ; Tumor Burden/genetics ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/metabolism ; Xenograft Model Antitumor Assays/methods ; Cyclin-Dependent Kinase-Activating Kinase ; Mice

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Tytuł:: Immune-Regulatory and Molecular Effects of Antidepressants on the Inflamed Human Keratinocyte HaCaT Cell Line.
Autorzy:: K C; Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland.
M M; Department of Psychiatry, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Department of Psychiatry, Medical University of Plovdiv, Plovdiv, Bulgaria.; IMPACT Strategic Research Centre, Deakin University, PO Box 281, Geelong, VIC, 3220, Australia.
M K; Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Aug; Vol. 39 (4), pp. 1211-1226. Date of Electronic Publication: 2021 May 04.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Antidepressive Agents/*pharmacology
Inflammation Mediators/*antagonists & inhibitors
Inflammation Mediators/*immunology
Keratinocytes/*drug effects
Keratinocytes/*immunology
Cell Survival/drug effects ; Cell Survival/immunology ; HaCaT Cells ; Humans

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Skocz do pozycji: 20.

Tytuł:: Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons.
Autorzy:: Bhat A; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, 570015, India.; Centre for Experimental Pharmacology and Toxicology, Central Animal Facility, JSS Academy of Higher Education & Research, Mysuru, India.; Neuroinflammation Group, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
Tan V; Neuroinflammation Group, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
Heng B; Neuroinflammation Group, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
Chow S; Neuroinflammation Group, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.
Basappa S; Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru, 570 006, India.
Essa MM; Department of Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat, Oman.; Ageing and Dementia Research Group, Sultan Qaboos University, Muscat, Oman.
Chidambaram SB; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, 570015, India. .; Centre for Experimental Pharmacology and Toxicology, Central Animal Facility, JSS Academy of Higher Education & Research, Mysuru, India. .; Special Interest Group - Brain, Behaviour and Cognitive Neurosciences, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, 570015, India. .
Guillemin GJ; Neuroinflammation Group, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2021 Aug; Vol. 39 (4), pp. 1238-1250. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Phosphoric Diester Hydrolases*/metabolism
Cerebral Cortex/*drug effects
Papaverine/*pharmacology
Phosphodiesterase Inhibitors/*pharmacology
Quinolinic Acid/*toxicity
Synapses/*drug effects
Cell Survival/drug effects ; Cell Survival/physiology ; Cells, Cultured ; Cerebral Cortex/cytology ; Cerebral Cortex/enzymology ; Dose-Response Relationship, Drug ; Humans ; Neurons/drug effects ; Neurons/enzymology ; Synapses/enzymology

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