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Wyszukujesz frazę ""Cells, Cultured"" wg kryterium: Temat


Tytuł :
Mathematical modelling reveals cellular dynamics within tumour spheroids.
Autorzy :
Bull JA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Mech F; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Quaiser T; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Waters SL; Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Byrne HM; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Aug 18; Vol. 16 (8), pp. e1007961. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput. Biol. Subsets: MEDLINE
MeSH Terms :
Models, Biological*
Spheroids, Cellular*/cytology
Spheroids, Cellular*/physiology
Tumor Cells, Cultured*/cytology
Tumor Cells, Cultured*/physiology
Animals ; Biomechanical Phenomena ; Cell Death/physiology ; Cell Hypoxia/physiology ; Cell Proliferation/physiology ; Computational Biology ; Humans
Czasopismo naukowe
Tytuł :
Measurement and visualization of cell membrane surface charge in fixed cultured cells related with cell morphology.
Autorzy :
Nishino M; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Matsuzaki I; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Musangile FY; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Takahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Iwahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Warigaya K; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kinoshita Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kojima F; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Murata SI; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
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Źródło :
PloS one [PLoS One] 2020 Jul 23; Vol. 15 (7), pp. e0236373. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
Typ publikacji :
Journal Article
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Cytodiagnosis*
Cell Line/*ultrastructure
Cell Membrane/*ultrastructure
Cells, Cultured/*ultrastructure
Anaphase/drug effects ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Division/drug effects ; Cell Membrane/drug effects ; Cells, Cultured/drug effects ; Fixatives/pharmacology ; Humans ; Membrane Potentials/drug effects ; Pepsin A/pharmacology ; Surface Properties
Czasopismo naukowe
Tytuł :
Supervised Machine Learning Algorithms for Bioelectromagnetics: Prediction Models and Feature Selection Techniques Using Data from Weak Radiofrequency Radiation Effect on Human and Animals Cells.
Autorzy :
Halgamuge MN; Department of Electrical and Electronic Engineering, The University of Melbourne, Parkville, VIC 3010, Australia.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Jun 26; Vol. 17 (12). Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE
MeSH Terms :
Algorithms*
Cells, Cultured*/radiation effects
Radio Waves*/adverse effects
Supervised Machine Learning*
Animals ; Area Under Curve ; Humans
Czasopismo naukowe
Tytuł :
BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION.
Autorzy :
Kobayashi A; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Autsavapromporn N; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Therapeutic Radiology and Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand.
Ahmad TAFT; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Agrotechnology and Biosciences, Malaysian Nuclear Agency, Bangi, Kajang, Malaysia.
Oikawa M; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Homma-Takeda S; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Furusawa Y; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Wang J; Key Laboratory of Ion Beam Bioengineering, Hefei Institute of Physical Science, Chinese Academy of Sciences and Anhui Province, No. 350 of Shushanhu Road, Hefei, PR China.
Konishi T; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
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Źródło :
Radiation protection dosimetry [Radiat Prot Dosimetry] 2019 May 01; Vol. 183 (1-2), pp. 142-146.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 8109958 Publication Model: Print Cited Medium: Internet ISSN: 1742-3406 (Electronic) Linking ISSN: 01448420 NLM ISO Abbreviation: Radiat Prot Dosimetry Subsets: MEDLINE
MeSH Terms :
A549 Cells/*radiation effects
Cell Communication/*radiation effects
DNA Breaks, Double-Stranded/*radiation effects
Gap Junctions/*radiation effects
Lung Neoplasms/*radiotherapy
Tumor Cells, Cultured/*radiation effects
Bystander Effect/radiation effects ; Cells, Cultured/radiation effects ; Coculture Techniques ; DNA Repair ; Fibroblasts/radiation effects ; Histones/analysis ; Humans ; Protons
Czasopismo naukowe
Tytuł :
Stem-Like Cancer Cells in a Dynamic 3D Culture System: A Model to Study Metastatic Cell Adhesion and Anti-Cancer Drugs.
Autorzy :
Paolillo M; Dipartmento di Scienze del Farmaco, Università degli Studi di Pavia, 27100 Pavia, Italy.
Colombo R; Dipartmento di Scienze del Farmaco, Università degli Studi di Pavia, 27100 Pavia, Italy.
Serra M; Dipartmento di Scienze del Farmaco, Università degli Studi di Pavia, 27100 Pavia, Italy.
Belvisi L; Dipartimento di Chimica, Università degli Studi di Milano, 20133 Milano, Italy.
Papetti A; Dipartmento di Scienze del Farmaco, Università degli Studi di Pavia, 27100 Pavia, Italy.
Ciusani E; Istituto Neurologico Carlo Besta, 20133 Milano, Italy.
Comincini S; Dipartimento di Biologia e Biotecnologie 'Lazzaro Spallanzani', Università degli Studi di Pavia, 27100 Pavia, Italy.
Schinelli S; Dipartmento di Scienze del Farmaco, Università degli Studi di Pavia, 27100 Pavia, Italy.
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Źródło :
Cells [Cells] 2019 Nov 13; Vol. 8 (11). Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
MeSH Terms :
Spheroids, Cellular*/drug effects
Tumor Cells, Cultured*
Neoplastic Stem Cells/*metabolism
Neoplastic Stem Cells/*pathology
Biomarkers ; Cell Adhesion ; Cell Culture Techniques ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Epithelial-Mesenchymal Transition/drug effects ; Fibroblasts/cytology ; Fibroblasts/pathology ; Fibroblasts/ultrastructure ; Gene Expression ; Humans ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/ultrastructure ; Phenotype
Czasopismo naukowe
Tytuł :
Efficient primary culture model of patient‑derived tumor cells from colorectal cancer using a Rho‑associated protein kinase inhibitor and feeder cells.
Autorzy :
Hong HK; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Pyo DH; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Kim TW; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea.
Yun NH; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea.
Lee YS; Department of Surgery, Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea.
Song SJ; Department of Surgery, Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea.
Lee WY; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Cho YB; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
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Źródło :
Oncology reports [Oncol Rep] 2019 Nov; Vol. 42 (5), pp. 2029-2038. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :
Journal Article
Journal Info :
Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2431 (Electronic) Linking ISSN: 1021335X NLM ISO Abbreviation: Oncol. Rep. Subsets: MEDLINE
MeSH Terms :
Amides/*pharmacology
Colorectal Neoplasms/*pathology
Feeder Cells/*cytology
Primary Cell Culture/*methods
Pyridines/*pharmacology
Tumor Cells, Cultured/*cytology
Aged ; Animals ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Culture Media, Conditioned/chemistry ; Female ; Humans ; Male ; Mice ; Microsatellite Repeats ; Middle Aged ; Neoplasm Transplantation ; Spheroids, Cellular/cytology ; Spheroids, Cellular/metabolism ; Tumor Cells, Cultured/drug effects
Czasopismo naukowe
Tytuł :
ABCA1 plays an anti-inflammatory role by affecting TLR4 at the feto-maternal interface.
Autorzy :
Ding N; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Liu N; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Yang L; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Han X; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China.
Lin L; Department of Gynecology and Obstetrics, Peking University International Hospital, Beijing 102206, China.
Long Y; Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, 100050 Beijing, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118390. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
MeSH Terms :
Maternal-Fetal Exchange*
ATP Binding Cassette Transporter 1/*metabolism
Toll-Like Receptor 4/*metabolism
Blotting, Western ; Cells, Cultured ; Chorion/metabolism ; Decidua/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Flow Cytometry ; Fluorescent Antibody Technique ; Humans ; Microscopy, Confocal ; Placenta/metabolism ; Pregnancy ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Hepatoprotective effects of Di Wu Yang Gan: A medicinal food against CCl 4 -induced hepatotoxicity in vivo and in vitro.
Autorzy :
Xu W; School of Pharmacy, Jiangsu University, Zhenjiang 212013, China; Department of Traditional Chinese Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang 212013, China.
Xiao M; Hepatic Disease Institute, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China; Hubei Provincial Academy of Traditional Chinese Medicine, Wuhan 430074, China.
Li J; School of Pharmacy, Jiangsu University, Zhenjiang 212013, China.
Chen Y; Clinical College of Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Sun Q; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
Li H; Hepatic Disease Institute, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China; Hubei Provincial Academy of Traditional Chinese Medicine, Wuhan 430074, China. Electronic address: .
Sun W; Army Hospital of the 81st Army Group, Zhangjiakou, China.
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Źródło :
Food chemistry [Food Chem] 2020 Oct 15; Vol. 327, pp. 127093. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
MeSH Terms :
Chemical and Drug Induced Liver Injury*/metabolism
Drugs, Chinese Herbal/*pharmacology
Liver/*drug effects
Alanine Transaminase/metabolism ; Animals ; Aspartate Aminotransferases/metabolism ; Carbon Tetrachloride ; Cells, Cultured ; Liver/metabolism ; Male ; Malondialdehyde/metabolism ; Mice
Czasopismo naukowe
Tytuł :
Aspirin restores endothelial function by mitigating 17β-estradiol-induced α-SMA accumulation and autophagy inhibition via Vps15 scaffold regulation of Beclin-1 phosphorylation.
Autorzy :
Wu H; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China.
Wu S; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China.
Zhu Y; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China.
Cheng J; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China.
Ye S; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China.
Xi Y; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China. Electronic address: .
Huang Q; Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Zhang Y; Department of Obstetrics, Ningbo Medical Center Li Huili Hospital, Ningbo, China. Electronic address: .
Bu S; Diabetes Research Center, School of Medicine, Ningbo University, Ningbo, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118383. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
MeSH Terms :
Actins/*metabolism
Aspirin/*pharmacology
Autophagy/*drug effects
Endothelium, Vascular/*drug effects
Estradiol/*metabolism
Vacuolar Sorting Protein VPS15/*metabolism
Animals ; Blotting, Western ; Cells, Cultured ; Endothelium, Vascular/ultrastructure ; Female ; Humans ; Immunoprecipitation ; Mice ; Mice, Inbred C57BL ; Microscopy, Electron, Transmission ; Phosphorylation/drug effects
Czasopismo naukowe
Tytuł :
Sodium butyrate promotes milk fat synthesis in bovine mammary epithelial cells via GPR41 and its downstream signalling pathways.
Autorzy :
Cheng J; College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Zhang Y; College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Ge Y; College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Li W; College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Cao Y; College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Qu Y; Human Animal Health Products Co., Ltd., Changchun 130062, China.
Liu S; Human Animal Health Products Co., Ltd., Changchun 130062, China.
Guo Y; Human Animal Health Products Co., Ltd., Changchun 130062, China.
Fu S; College of Veterinary Medicine, Jilin University, Changchun 130062, China. Electronic address: .
Liu J; College of Veterinary Medicine, Jilin University, Changchun 130062, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118375. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
MeSH Terms :
Butyric Acid/*pharmacology
Glycolipids/*biosynthesis
Glycoproteins/*biosynthesis
Mammary Glands, Animal/*drug effects
Receptors, G-Protein-Coupled/*metabolism
Signal Transduction/*drug effects
Animals ; Blotting, Western ; Carbazoles ; Cattle ; Cells, Cultured ; Female ; Immunoprecipitation ; MAP Kinase Signaling System/drug effects ; Mammary Glands, Animal/metabolism ; Naphthalenes ; Real-Time Polymerase Chain Reaction ; Sirtuin 1/metabolism ; Sterol Regulatory Element Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Autorzy :
Zheng M; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Williams EP; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Malireddi RKS; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Karki R; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Banoth B; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Burton A; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Webby R; Department of Infectious Disease, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Channappanavar R; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; Department of Acute and Tertiary Care, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jonsson CB; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Kanneganti TD; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 09; Vol. 295 (41), pp. 14040-14052. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
MeSH Terms :
Pyroptosis*
Caspase 8/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism
Animals ; Cells, Cultured ; Coronavirus/physiology ; Coronavirus Infections/metabolism ; Coronavirus Infections/pathology ; Coronavirus Infections/veterinary ; Cytokines/metabolism ; Inflammasomes/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Macrophages/cytology ; Macrophages/metabolism ; Macrophages/virology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Necroptosis ; Phosphate-Binding Proteins/genetics ; Phosphate-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle.
Autorzy :
Theparambil SM; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Hosford PS; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Ruminot I; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Kopach O; Institute of Neurology, University College London, London, UK.
Reynolds JR; Institute of Neurology, University College London, London, UK.
Sandoval PY; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Rusakov DA; Institute of Neurology, University College London, London, UK.
Barros LF; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Gourine AV; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 08; Vol. 11 (1), pp. 5073. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Astrocytes/*metabolism
Bicarbonates/*metabolism
Brain/*metabolism
Extracellular Space/*metabolism
Acetazolamide/pharmacology ; Adenosine Triphosphate/metabolism ; Animals ; Astrocytes/drug effects ; Carbonic Anhydrases/metabolism ; Cells, Cultured ; Electric Stimulation ; Fluorescence ; Hippocampus/metabolism ; Hydrogen-Ion Concentration ; Mice, Inbred C57BL ; Models, Biological ; Neurons/drug effects ; Neurons/metabolism ; Purinergic Antagonists/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Receptors, Purinergic/metabolism ; Signal Transduction ; Sodium-Bicarbonate Symporters/metabolism
Czasopismo naukowe
Tytuł :
Identification of loss-of-function HOXA2 mutations in Chinese families with dominant bilateral microtia.
Autorzy :
Si N; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, China.
Meng X; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, China.
Lu X; Department of Plastic Surgery, Affiliated Hospital of Weifang Medical University, China.
Zhao X; Department of Plastic Surgery, The Second Hospital of Hebei Medical University, China.
Li C; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Yang M; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Zhang Y; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Wang C; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Guo P; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Zhang X; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, China.
Pan B; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China. Electronic address: .
Jiang H; Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144945. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Loss of Function Mutation*
Congenital Microtia/*genetics
Homeodomain Proteins/*genetics
Cells, Cultured ; Congenital Microtia/pathology ; Female ; Genes, Dominant ; HEK293 Cells ; Homeodomain Proteins/metabolism ; Humans ; Male ; Pedigree ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Single cell sequencing revealed the underlying pathogenesis of the development of osteoarthritis.
Autorzy :
Li C; Rheumatology Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Luo J; Rheumatology Department, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xu X; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China.
Zhou Z; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China.
Ying S; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China.
Liao X; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China.
Wu K; Wenzhou Center for Disease Control and Prevention, Wenzhou, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144939. Date of Electronic Publication: 2020 Jul 05.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Actins/*genetics
Collagen Type VI/*genetics
Osteoarthritis/*genetics
Actins/metabolism ; Aged ; Cells, Cultured ; Chondrocytes/metabolism ; Collagen Type VI/metabolism ; Female ; Fibroblasts/metabolism ; Humans ; Male ; Middle Aged ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Protein Interaction Maps ; RNA-Seq ; Single-Cell Analysis ; Transcriptome ; Up-Regulation
Czasopismo naukowe
Tytuł :
Down-regulation of circ_0061140 attenuates ectopic endometrial cell proliferation, migration and invasion in endometriosis via inactivating Notch2.
Autorzy :
Xu A; Department of Clinical Laboratory, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jiang M; Department of Clinical Laboratory, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Li S; Department of Clinical Laboratory, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fei Q; Outpatient Department, Huai'an Second People's Hospital, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144926. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Cell Movement*
Cell Proliferation*
Endometriosis/*genetics
RNA, Circular/*genetics
Cells, Cultured ; Down-Regulation ; Endometriosis/metabolism ; Endometriosis/pathology ; Endometrium/metabolism ; Endometrium/pathology ; Female ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Circular/metabolism ; Receptor, Notch2/genetics ; Receptor, Notch2/metabolism
Czasopismo naukowe
Tytuł :
Overexpression of the Tuberous sclerosis complex 2 (TSC2) gene inhibits goat myoblasts proliferation and differentiation in understanding the underlying mechanism of muscle development.
Autorzy :
Lyu M; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shalitana A; Department of Xinjiang Institute for Cancer Research, Xinjiang Cancer Hospital of Xinjiang Medical University, Urumqi 830011, China.
Luo J; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
He H; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Sun S; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Wang P; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Oct 05; Vol. 757, pp. 144943. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Cell Differentiation*
Cell Proliferation*
Muscle Development*
Myoblasts/*metabolism
Tuberous Sclerosis Complex 2 Protein/*genetics
Animals ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cells, Cultured ; Goats ; Myoblasts/cytology ; Myoblasts/physiology ; Ribosomal Protein S6 Kinases, 70-kDa/genetics ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Tuberous Sclerosis Complex 2 Protein/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Presynaptically silent synapses are modulated by the density of surrounding astrocytes.
Autorzy :
Oyabu K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Takeda K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Kawano H; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Kubota K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Watanabe T; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Harata NC; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Katsurabayashi S; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. Electronic address: .
Iwasaki K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 76-82. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Japanese Pharmacological Society Country of Publication: Japan NLM ID: 101167001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-8648 (Electronic) Linking ISSN: 13478613 NLM ISO Abbreviation: J Pharmacol Sci Subsets: MEDLINE
MeSH Terms :
Synaptic Transmission*
Astrocytes/*physiology
Brain/*cytology
Neurons/*physiology
Synapses/*physiology
Animals ; Astrocytes/pathology ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Female ; Mice, Inbred ICR ; Neurons/pathology ; Phylogeny ; Pregnancy
Czasopismo naukowe
Tytuł :
Ex vivo culture of head and neck cancer explants in cell sheet for testing chemotherapeutic sensitivity.
Autorzy :
Lee J; Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Gyeonggi-do, 13496, Republic of Korea.
You JH; Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Gyeonggi-do, 13496, Republic of Korea.
Shin D; Western Seoul Center, Korea Basic Science Institute, Seoul, Republic of Korea.
Roh JL; Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Gyeonggi-do, 13496, Republic of Korea. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2020 Oct; Vol. 146 (10), pp. 2497-2507. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1335 (Electronic) Linking ISSN: 01715216 NLM ISO Abbreviation: J. Cancer Res. Clin. Oncol. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Drug Screening Assays, Antitumor/*methods
Head and Neck Neoplasms/*drug therapy
Head and Neck Neoplasms/*pathology
Squamous Cell Carcinoma of Head and Neck/*drug therapy
Squamous Cell Carcinoma of Head and Neck/*pathology
Cell Hypoxia/physiology ; Cell Survival/physiology ; Cisplatin/pharmacology ; Docetaxel/pharmacology ; Dose-Response Relationship, Drug ; Head and Neck Neoplasms/blood ; Humans ; Organ Culture Techniques/methods ; Squamous Cell Carcinoma of Head and Neck/blood ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Effect of NMO-IgG on the interleukin-6 cascade in astrocytes via activation of the JAK/STAT3 signaling pathway.
Autorzy :
Du L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Chang H; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Xu W; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wei Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wang Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Yin L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
Zhang X; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118217. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Astrocytes/*metabolism
Immunoglobulin G/*blood
Interleukin-6/*metabolism
Janus Kinases/*metabolism
Neuromyelitis Optica/*blood
STAT3 Transcription Factor/*metabolism
Adult ; Aged ; Animals ; Astrocytes/drug effects ; Autoantibodies/blood ; Autoantibodies/pharmacology ; Cells, Cultured ; Female ; Humans ; Immunoglobulin G/pharmacology ; Interleukin-6/agonists ; Male ; Middle Aged ; Rats ; Rats, Wistar ; STAT3 Transcription Factor/agonists ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Young Adult
Czasopismo naukowe
Tytuł :
Disruption of classical estrogenic targets in brown trout primary hepatocytes by the model androgens testosterone and dihydrotestosterone.
Autorzy :
Lopes C; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto (U.Porto), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, P 4450-208 Matosinhos, Portugal; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U.Porto), Laboratory of Histology and Embryology, Department of Microscopy, Rua Jorge Viterbo Ferreira 228, P 4050-313 Porto, Portugal.
Madureira TV; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto (U.Porto), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, P 4450-208 Matosinhos, Portugal; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U.Porto), Laboratory of Histology and Embryology, Department of Microscopy, Rua Jorge Viterbo Ferreira 228, P 4050-313 Porto, Portugal. Electronic address: .
Gonçalves JF; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto (U.Porto), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, P 4450-208 Matosinhos, Portugal; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U.Porto), Department of Aquatic Production, Rua Jorge Viterbo Ferreira 228, P 4050-313 Porto, Portugal.
Rocha E; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto (U.Porto), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, P 4450-208 Matosinhos, Portugal; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto (U.Porto), Laboratory of Histology and Embryology, Department of Microscopy, Rua Jorge Viterbo Ferreira 228, P 4050-313 Porto, Portugal.
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Oct; Vol. 227, pp. 105586. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8500246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1514 (Electronic) Linking ISSN: 0166445X NLM ISO Abbreviation: Aquat Toxicol Subsets: MEDLINE
MeSH Terms :
Androgens/*toxicity
Dihydrotestosterone/*toxicity
Estrogens/*metabolism
Hepatocytes/*drug effects
Testosterone/*toxicity
Trout/*metabolism
Water Pollutants, Chemical/*toxicity
Androgens/metabolism ; Animals ; Cells, Cultured ; Dihydrotestosterone/metabolism ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Estrogens/genetics ; Gene Expression/drug effects ; Hepatocytes/metabolism ; Male ; Primary Cell Culture ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Testosterone/metabolism ; Vitellogenins/genetics ; Vitellogenins/metabolism ; Water Pollutants, Chemical/metabolism
Czasopismo naukowe

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