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Tytuł:
Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats.
Autorzy:
Wu Z; Department of Trauma and Arthrology, First Affiliated Hospital of Shaoyang University, Shaoyang, Hunan, China.
Yang Y; Department of Trauma and Arthrology, First Affiliated Hospital of Shaoyang University, Shaoyang, Hunan, China.
Wang M; Department of Trauma and Arthrology, First Affiliated Hospital of Shaoyang University, Shaoyang, Hunan, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2024 Mar 20; Vol. 19 (1), pp. 192. Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Fractures, Bone*/metabolism
Mesenchymal Stem Cells*/metabolism
Animals ; Humans ; Rats ; Angiogenesis ; Bone Marrow Cells ; Cell Differentiation/genetics ; Cells, Cultured ; Endothelial Cells ; Osteogenesis/genetics ; Receptor, Nerve Growth Factor/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury.
Autorzy:
Chen SY; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Chen YL; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833401, Taiwan.; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan.
Li PC; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Cheng TS; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.
Chu YS; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Shen YS; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.; Department of Biomedical Engineering, National Taiwan University, Taipei, 106319, Taiwan.
Chen HT; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Tsai WN; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Huang CL; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Sieber M; Bionet Therapeutics, Taipei, 114065, Taiwan.
Yeh YC; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung, 204201, Taiwan.; Program in Molecular Medicine, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Liu HS; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 701401, Taiwan.; Center for Cancer Research, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan.; Teaching and Research Center, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 812015, Taiwan.
Chiang CL; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, 43210, USA.; Comprehensive Cancer Center, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.
Chang CH; Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan.; Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan, 320315, Taiwan.
Lee AS; Spot Biosystems Ltd., Palo Alto, CA, 94305, USA.
Tseng YH; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, 112201, Taiwan.
Lee LJ; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, 43210, USA. .; Spot Biosystems Ltd., Palo Alto, CA, 94305, USA. .
Liao HJ; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Medical Research, Far Eastern Memorial Hospital, New Taipei City, 220216, Taiwan. .
Yip HK; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 833401, Taiwan. .; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan. .; Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833401, Taiwan. .; Department of Nursing, Asia University, Taichung, 413305, Taiwan. .; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 404328, Taiwan. .
Huang CF; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .; Department of Biochemistry, School of Medicine, Kaohsiung Medical University, Kaohsiung, 807378, Taiwan. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Mar 19; Vol. 31 (1), pp. 30. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperoxia*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Extracellular Vesicles*/physiology
Acute Lung Injury*/therapy
Acute Lung Injury*/metabolism
Rats ; Animals ; Cells, Cultured ; Inflammation ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism ; Fibrosis
Czasopismo naukowe
Tytuł:
Investigation of the impact of bromodomain inhibition on cytoskeleton stability and contraction.
Autorzy:
Bigger-Allen A; Urological Diseases Research Center, Boston Children's Hospital, Enders Bldg 1061.4, 300 Longwood Avenue, Boston, MA, 02115, USA.; Biological & Biomedical Sciences Program, Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Gheinani AH; Urological Diseases Research Center, Boston Children's Hospital, Enders Bldg 1061.4, 300 Longwood Avenue, Boston, MA, 02115, USA.; Department of Surgery, Harvard Medical School, Boston, MA, USA.; Functional Urology Research Group, Department for BioMedical Research DBMR, University of Bern, Bern, Switzerland.; Department of Urology, Inselspital University Hospital, 3010, Bern, Switzerland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Adam RM; Urological Diseases Research Center, Boston Children's Hospital, Enders Bldg 1061.4, 300 Longwood Avenue, Boston, MA, 02115, USA. .; Department of Surgery, Harvard Medical School, Boston, MA, USA. .; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 16; Vol. 22 (1), pp. 184. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Nuclear Proteins*/metabolism
Transcription Factors*/metabolism
Humans ; Cytoskeleton/metabolism ; Myocytes, Smooth Muscle ; Transforming Growth Factor beta/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł:
An efficient and cost-effective method for disrupting genes in RAW264.7 macrophages using CRISPR-Cas9.
Autorzy:
Hossain MJ; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
O'Connor TJ; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 14; Vol. 19 (3), pp. e0299513. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
CRISPR-Cas Systems*/genetics
RNA, Guide, CRISPR-Cas Systems*
Animals ; Mice ; Cost-Benefit Analysis ; Gene Editing/methods ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Autotaxin inhibition attenuates the aortic valve calcification by suppressing inflammation-driven fibro-calcific remodeling of valvular interstitial cells.
Autorzy:
Yoon D; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Choi B; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Kim JE; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Kim EY; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Chung SH; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Min HJ; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Sung Y; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Chang EJ; Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .; Stem Cell Immunomodulation Research Center, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .
Song JK; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .
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Źródło:
BMC medicine [BMC Med] 2024 Mar 14; Vol. 22 (1), pp. 122. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Aortic Valve Stenosis*/drug therapy
Calcinosis*/drug therapy
Aortic Valve/*pathology
Humans ; Animals ; Mice ; Rabbits ; Osteogenesis ; Cells, Cultured ; Fibrosis ; Cholesterol ; Receptors, Interleukin-1 ; Lipids
SCR Disease Name:
Aortic Valve, Calcification of
Czasopismo naukowe
Tytuł:
Knockdown of the UL-16 binding protein 1 promotes osteoblast differentiation of human mesenchymal stem cells by activating the SMAD2/3 pathway.
Autorzy:
Lai Z; Department of Orthopedic Surgery, Huadu District People's Hospital of Guangzhou, 48 Xinhua Road, Xinhua Street, Huadu District, Guangzhou, 510800, Guangdong, China. .
Li M; Shiling Town Health Center, 19 Qiling Street, Huadu District, Guangzhou, 510800, Guangdong, China.
Yang X; Department of Orthopedic Surgery, Huadu District People's Hospital of Guangzhou, 48 Xinhua Road, Xinhua Street, Huadu District, Guangzhou, 510800, Guangdong, China.
Xian Z; Department of Orthopedic Surgery, Huadu District People's Hospital of Guangzhou, 48 Xinhua Road, Xinhua Street, Huadu District, Guangzhou, 510800, Guangdong, China.
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Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Mar 13; Vol. 25 (1), pp. 213. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
Osteoporosis*/genetics
Humans ; Carrier Proteins/metabolism ; Cell Differentiation/genetics ; Cells, Cultured ; Lymphotoxin-alpha/metabolism ; Osteoblasts/metabolism ; Osteocalcin/metabolism ; Osteogenesis/genetics ; Smad2 Protein/metabolism
Czasopismo naukowe
Tytuł:
Quercetin improves epithelial regeneration from airway basal cells of COPD patients.
Autorzy:
McCluskey ES; Center for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA, 19140, USA.
Liu N; Center for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA, 19140, USA.
Pandey A; Center for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA, 19140, USA.
Marchetti N; Department of Thoracic Medicine and Surgery, Temple University Health System, Philadelphia, PA, 19140, USA.
Kelsen SG; Department of Thoracic Medicine and Surgery, Temple University Health System, Philadelphia, PA, 19140, USA.
Sajjan US; Center for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA, 19140, USA. .; Department of Microbiology, Immunology and Inflammation, Lewis-Katz Medical School, Temple University, Philadelphia, PA, 19140, USA. .; Department of Thoracic Medicine and Surgery, Temple University Health System, Philadelphia, PA, 19140, USA. .
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Źródło:
Respiratory research [Respir Res] 2024 Mar 11; Vol. 25 (1), pp. 120. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/therapeutic use
Quercetin*/metabolism
Pulmonary Disease, Chronic Obstructive*/diagnosis
Pulmonary Disease, Chronic Obstructive*/drug therapy
Pulmonary Disease, Chronic Obstructive*/genetics
Humans ; Interleukin-8/metabolism ; Dimethyl Sulfoxide/metabolism ; Dimethyl Sulfoxide/pharmacology ; Bronchi/metabolism ; Epithelial Cells/metabolism ; Cells, Cultured ; Transcription Factors/metabolism ; Homeodomain Proteins/metabolism ; Homeodomain Proteins/pharmacology
Czasopismo naukowe
Tytuł:
Biochemical and functional characterization of heat-inactivated coelomic fluid from earthworms as a potential alternative for fetal bovine serum in animal cell culture.
Autorzy:
Rossan Mathews MG; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Subramaniam R; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Venkatachalam S; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Selvan Christyraj JRS; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India. .
Yesudhason BV; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.
Kalimuthu K; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.
Mohan M; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Tech, Atlanta, USA.
Selvan Christyraj JD; Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5606. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Serum Albumin, Bovine*
Oligochaeta*
Humans ; Animals ; Culture Media, Serum-Free ; Culture Media/chemistry ; Hot Temperature ; Cell Culture Techniques/methods ; HeLa Cells ; Vitamins ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Motor neurons and endothelial cells additively promote development and fusion of human iPSC-derived skeletal myocytes.
Autorzy:
Das S; Department of Neurosurgery, Center for Brain Injury & Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, 19104, USA. .
Hilman MC; Department of Neurosurgery, Center for Brain Injury & Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, 19104, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.
Yang F; Department of Medicine, Penn Institute for Regenerative Medicine, Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Mourkioti F; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Musculoskeletal Program, Penn Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Yang W; Department of Medicine, Penn Institute for Regenerative Medicine, Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Cullen DK; Department of Neurosurgery, Center for Brain Injury & Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, 19104, USA. .; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. .; Musculoskeletal Program, Penn Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .
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Źródło:
Skeletal muscle [Skelet Muscle] 2024 Mar 07; Vol. 14 (1), pp. 5. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Induced Pluripotent Stem Cells*/metabolism
Humans ; Endothelial Cells ; Cells, Cultured ; Muscle Fibers, Skeletal/metabolism ; Motor Neurons ; Cell Differentiation/physiology
Czasopismo naukowe
Tytuł:
The Specific Molecular Changes Induced by Diabetic Conditions in Valvular Endothelial Cells and upon Their Interactions with Monocytes Contribute to Endothelial Dysfunction.
Autorzy:
Tucureanu MM; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
Ciortan L; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
Macarie RD; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
Mihaila AC; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
Droc I; Cardiovascular Surgery Department, Central Military Hospital, 010825 Bucharest, Romania.
Butoi E; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
Manduteanu I; Biopathology and Therapy of Inflammation, Institute of Cellular Biology and Pathology 'Nicolae Simionescu', 050568 Bucharest, Romania.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/metabolism
Diabetes Mellitus*/metabolism
Humans ; Monocytes/metabolism ; Cell Adhesion ; Glucose/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Proanthocyanidins Ameliorate LPS-Inhibited Osteogenesis of PDLSCs by Restoring Lysine Lactylation.
Autorzy:
Wu Y; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Wang X; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Zhang Y; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Wen Z; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Li Y; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Zhang K; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Gosar N; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Li Q; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Mao J; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
Gong S; Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430033, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 03; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 03.
Typ publikacji:
Journal Article
MeSH Terms:
Proanthocyanidins*/metabolism
Periodontitis*/metabolism
Humans ; Rats ; Animals ; Osteogenesis/physiology ; Periodontal Ligament ; Lipopolysaccharides/metabolism ; Lysine/metabolism ; Epigenesis, Genetic ; Stem Cells/metabolism ; Cell Differentiation/physiology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers.
Autorzy:
Sone K; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan.; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Sakamaki Y; Graduate School of Pharmaceutical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Hirose S; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan.; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Inagaki M; Graduate School of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Tachikawa M; Graduate School of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Tokushima, 770-8505, Japan.
Yoshino D; Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.
Funamoto K; Graduate School of Biomedical Engineering, Tohoku University, 6-6-12 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8579, Japan. .; Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan. .; Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki-aza Aoba, Aoba-ku, Sendai, Miyagi, 980-8597, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 02; Vol. 14 (1), pp. 5164. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/physiology
Glucose*/pharmacology
Humans ; Hypoxia ; Oxygen ; Cell Movement ; Cell Hypoxia ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Epithelial Cells or Vascular Smooth Muscle Cells in a Peripheral Blood Smear?
Autorzy:
Yang W; Zhejiang Provincial People’s Hospital Bijie Hospital, Department of Clinical Laboratory, Bijie, China
Wang Y; Xinchang Hospital Affiliated to Wenzhou Medical University, Department of Thoracic Surgery, Xinchang, China
Pan W; Haiyan People’s Hospital, Department of Clinical Laboratory, Haiyan, China
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Źródło:
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2024 Mar 01; Vol. 41 (1), pp. 47-48. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Muscle, Smooth, Vascular*
Epithelial Cells*
Humans ; Myocytes, Smooth Muscle ; Cells, Cultured
Czasopismo naukowe
Tytuł:
An In Vitro Study Evaluating the Safety of Mesalazine on Human Nasoepithelial Cells.
Autorzy:
Murphy W; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Liu S; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Javadiyan S; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Vyskocil E; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; Department of Otolaryngology, Head and Neck Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Feizi S; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Callejas C; Department of Otolaryngology, Head and Neck Surgery, The Ohio State University, Columbus, OH 43210, USA.; Department of Otolaryngology, Pontificia Universidad Católica de Chile, Santiago 8320165, Chile.
Wormald PJ; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Vreugde S; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
Psaltis AJ; Department of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, Central Adelaide Local Health Network, Adelaide 5011, Australia.; The Department of Surgery, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide 5000, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Mesalamine*/therapeutic use
Sinusitis*/metabolism
Humans ; Tumor Necrosis Factor-alpha/metabolism ; Cells, Cultured ; Nasal Mucosa/metabolism ; Interleukin-6/metabolism ; Anti-Inflammatory Agents/pharmacology ; Chronic Disease ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
Fibroblasts and Endothelial Cells in Three-Dimensional Models: A New Tool for Addressing the Pathogenesis of Systemic Sclerosis as a Prototype of Fibrotic Vasculopathies.
Autorzy:
Bodio C; Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy.
Milesi A; Laboratory of Clinical Neurobiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 28824 Piancavallo, Italy.
Lonati PA; Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy.
Chighizola CB; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.; U.O.C. Clinica Reumatologica Pediatrica, ASST G. Pini-CTO, 20122 Milan, Italy.
Mauro A; Laboratory of Clinical Neurobiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 28824 Piancavallo, Italy.; Department of Neuroscience, University of Turin, 10124 Turin, Italy.
Pradotto LG; Laboratory of Clinical Neurobiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 28824 Piancavallo, Italy.; Department of Neuroscience, University of Turin, 10124 Turin, Italy.
Meroni PL; Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy.
Borghi MO; Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy.; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Raschi E; Experimental Laboratory of Immunological and Rheumatologic Researches, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Scleroderma, Systemic*/pathology
Vascular Diseases*/pathology
Animals ; Humans ; Endothelial Cells/pathology ; Skin/pathology ; Fibrosis ; Fibroblasts/pathology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Piper sarmentosum Roxb. Inhibits Angiotensin-Converting Enzyme Activity in Phorbol 12-Myristate-13-Acetate-Induced Endothelial Cells.
Autorzy:
Ugusman A; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Ismail SM; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.; Mushroom Research Centre, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
Nor Hisam NS; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.; Programme of Biomedical Science, Centre for Toxicology & Health Risk Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Hui CK; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Saleh MSM; Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Abdul Karim AK; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Othman NS; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Hamid AA; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Aminuddin A; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 28; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Piper*
Phorbols*/metabolism
Phorbols*/pharmacology
Humans ; Antihypertensive Agents/pharmacology ; Myristates/metabolism ; Myristates/pharmacology ; Angiotensin II/metabolism ; Endothelial Cells/metabolism ; Cells, Cultured ; Peptidyl-Dipeptidase A/metabolism ; Receptor, Angiotensin, Type 1/metabolism ; RNA, Messenger/metabolism ; Acetates/pharmacology
Czasopismo naukowe
Tytuł:
Impact of tissue factor expression and administration routes on thrombosis development induced by mesenchymal stem/stromal cell infusions: re-evaluating the dogma.
Autorzy:
Hoang VT; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam. .
Le DS; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam.
Hoang DM; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam.
Phan TTK; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam.
Ngo LAT; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam.; Center of Applied Science and Regenerative Medicine, Vinmec Health Care System, 458 Minh Khai, Hanoi, 10000, Vietnam.
Nguyen TK; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam.
Bui VA; Center of Applied Science and Regenerative Medicine, Vinmec Health Care System, 458 Minh Khai, Hanoi, 10000, Vietnam.
Nguyen Thanh L; Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Health Care System, 458 Minh Khai, Hai Ba Trung District, Hanoi, 100000, Vietnam. .; Vinmec International Hospital - Times City, Vinmec Health Care System, 458 Minh Khai, Hanoi, 11622, Vietnam. .; College of Health Science, VinUniversity, Vinhomes Ocean Park, Gia Lam District, Hanoi, 1310, Vietnam. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Feb 27; Vol. 15 (1), pp. 56. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Thrombosis*/genetics
Mesenchymal Stem Cells*/metabolism
Mesenchymal Stem Cell Transplantation*
Humans ; Thromboplastin/genetics ; Thromboplastin/metabolism ; Cells, Cultured ; Human Umbilical Vein Endothelial Cells/metabolism ; Anticoagulants ; Umbilical Cord
Czasopismo naukowe
Tytuł:
Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation.
Autorzy:
Kageyama T; Kanagawa Institute of Industrial Science and Technology, 3-2-1 Sakado Takatsu-ku, Kawasaki, Kanagawa, 213-0012, Japan.; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.; Institute of Advanced Sciences, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.
Seo J; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.; Institute of Advanced Sciences, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.
Yan L; Kanagawa Institute of Industrial Science and Technology, 3-2-1 Sakado Takatsu-ku, Kawasaki, Kanagawa, 213-0012, Japan.; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.; Institute of Advanced Sciences, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.
Fukuda J; Kanagawa Institute of Industrial Science and Technology, 3-2-1 Sakado Takatsu-ku, Kawasaki, Kanagawa, 213-0012, Japan. .; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan. .; Institute of Advanced Sciences, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 27; Vol. 14 (1), pp. 4709. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Hair Follicle*/metabolism
Oxytocin*/pharmacology
Oxytocin*/metabolism
Cinnamates*
Humans ; Receptors, Oxytocin/genetics ; Receptors, Oxytocin/metabolism ; Cells, Cultured ; Hair ; Organoids
Czasopismo naukowe
Tytuł:
Cellular transfection using rapid decrease in hydrostatic pressure.
Autorzy:
Huang S; Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Suo NJ; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, M5S 3G5, Canada.
Henderson TR; Department of Medical Genetics, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.
Macgregor RB Jr; Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Henderson JT; Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 26; Vol. 14 (1), pp. 4631. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Electroporation*/methods
Nucleic Acids*
Hydrostatic Pressure ; Transfection ; Cells, Cultured
Czasopismo naukowe
Tytuł:
Advantages of Using 3D Spheroid Culture Systems in Toxicological and Pharmacological Assessment for Osteogenesis Research.
Autorzy:
Yun C; Department of Pharmacy, Research Institute for Drug Development, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Kim SH; Department of Pharmacy, Research Institute for Drug Development, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Kim KM; Department of Pharmacy, Research Institute for Drug Development, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Yang MH; Department of Pharmacy, Research Institute for Drug Development, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Byun MR; College of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Republic of Korea.
Kim JH; Department of Medical Beauty Care, Dongguk University Wise, Gyeongju 38066, Republic of Korea.
Kwon D; Jeju Research Institute of Pharmaceutical Sciences, College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea.
Pham HTM; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea.
Kim HS; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea.
Kim JH; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea.
Jung YS; Department of Pharmacy, Research Institute for Drug Development, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 21; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Osteogenesis*
Cell Culture Techniques*/methods
Animals ; Cells, Cultured ; Cell Differentiation/physiology ; Bone and Bones
Czasopismo naukowe

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