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Wyszukujesz frazę ""Cells, Cultured"" wg kryterium: Temat


Tytuł :
Mathematical modelling reveals cellular dynamics within tumour spheroids.
Autorzy :
Bull JA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Mech F; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Quaiser T; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Waters SL; Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Byrne HM; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Aug 18; Vol. 16 (8), pp. e1007961. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Spheroids, Cellular*/cytology
Spheroids, Cellular*/physiology
Tumor Cells, Cultured*/cytology
Tumor Cells, Cultured*/physiology
Animals ; Biomechanical Phenomena ; Cell Death/physiology ; Cell Hypoxia/physiology ; Cell Proliferation/physiology ; Computational Biology ; Humans
Czasopismo naukowe
Tytuł :
Measurement and visualization of cell membrane surface charge in fixed cultured cells related with cell morphology.
Autorzy :
Nishino M; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Matsuzaki I; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Musangile FY; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Takahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Iwahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Warigaya K; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kinoshita Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kojima F; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Murata SI; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
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Źródło :
PloS one [PLoS One] 2020 Jul 23; Vol. 15 (7), pp. e0236373. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Cytodiagnosis*
Cell Line/*ultrastructure
Cell Membrane/*ultrastructure
Cells, Cultured/*ultrastructure
Anaphase/drug effects ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Division/drug effects ; Cell Membrane/drug effects ; Cells, Cultured/drug effects ; Fixatives/pharmacology ; Humans ; Membrane Potentials/drug effects ; Pepsin A/pharmacology ; Surface Properties
Czasopismo naukowe
Tytuł :
Supervised Machine Learning Algorithms for Bioelectromagnetics: Prediction Models and Feature Selection Techniques Using Data from Weak Radiofrequency Radiation Effect on Human and Animals Cells.
Autorzy :
Halgamuge MN; Department of Electrical and Electronic Engineering, The University of Melbourne, Parkville, VIC 3010, Australia.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Jun 26; Vol. 17 (12). Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Cells, Cultured*/radiation effects
Radio Waves*/adverse effects
Supervised Machine Learning*
Animals ; Area Under Curve ; Humans
Czasopismo naukowe
Tytuł :
BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION.
Autorzy :
Kobayashi A; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Autsavapromporn N; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Therapeutic Radiology and Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand.
Ahmad TAFT; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Agrotechnology and Biosciences, Malaysian Nuclear Agency, Bangi, Kajang, Malaysia.
Oikawa M; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Homma-Takeda S; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Furusawa Y; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Wang J; Key Laboratory of Ion Beam Bioengineering, Hefei Institute of Physical Science, Chinese Academy of Sciences and Anhui Province, No. 350 of Shushanhu Road, Hefei, PR China.
Konishi T; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
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Źródło :
Radiation protection dosimetry [Radiat Prot Dosimetry] 2019 May 01; Vol. 183 (1-2), pp. 142-146.
Typ publikacji :
Journal Article
MeSH Terms :
A549 Cells/*radiation effects
Cell Communication/*radiation effects
DNA Breaks, Double-Stranded/*radiation effects
Gap Junctions/*radiation effects
Lung Neoplasms/*radiotherapy
Tumor Cells, Cultured/*radiation effects
Bystander Effect/radiation effects ; Cells, Cultured/radiation effects ; Coculture Techniques ; DNA Repair ; Fibroblasts/radiation effects ; Histones/analysis ; Humans ; Protons
Czasopismo naukowe
Tytuł :
Gadd45α affects retinal ganglion cell injury in chronic ocular hypertension rats by regulating p38MAPK pathway.
Autorzy :
Sun RX; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Sun ZH; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Ren Q; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Li L; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Yin L; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Li F; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China.
Su X; Department of Ophthalmology, The First Hospital of Shijiazhuang City, Shijiazhuang 050000, Hebei Province, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Dec 30; Vol. 763, pp. 145030. Date of Electronic Publication: 2020 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Cell Cycle Proteins/*metabolism
Ocular Hypertension/*metabolism
Retinal Ganglion Cells/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Apoptosis ; Cell Cycle Proteins/genetics ; Cells, Cultured ; Humans ; Male ; Oxidative Stress ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
CircZNF609 aggravates neuropathic pain via miR-22-3p/ENO1 axis in CCI rat models.
Autorzy :
Li L; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Luo Y; Department of Thoracic Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Zhang Y; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Wei M; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Zhang M; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Liu H; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China.
Su Z; Department of Anesthesiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Dec 30; Vol. 763, pp. 145069. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*metabolism
Neuralgia/*metabolism
Phosphopyruvate Hydratase/*genetics
RNA, Circular/*metabolism
Animals ; Cells, Cultured ; HEK293 Cells ; Humans ; Male ; MicroRNAs/genetics ; Neuralgia/genetics ; Phosphopyruvate Hydratase/metabolism ; RNA, Circular/genetics ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Phenotypical and functional alteration of unconventional T cells in severe COVID-19 patients.
Autorzy :
Jouan Y; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de Médecine Intensive et Réanimation, Centre Hospitalier Régional Universitaire, Tours, France.; Service de chirurgie cardiaque et de réanimation chirurgicale cardio-vasculaire, Centre Hospitalier Régional Universitaire, Tours, France.
Guillon A; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de Médecine Intensive et Réanimation, Centre Hospitalier Régional Universitaire, Tours, France.
Gonzalez L; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.
Perez Y; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de Médecine Intensive et Réanimation, Centre Hospitalier Régional Universitaire, Tours, France.
Boisseau C; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.
Ehrmann S; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de Médecine Intensive et Réanimation, Centre Hospitalier Régional Universitaire, Tours, France.
Ferreira M; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de pneumologie, Centre Hospitalier Régional Universitaire, Tours, France.
Daix T; Intensive Care Unit, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale CIC1435, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale UMR 1092, University of Limoges, Limoges, France.
Jeannet R; Intensive Care Unit, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale CIC1435, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale UMR 1092, University of Limoges, Limoges, France.
François B; Intensive Care Unit, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale CIC1435, Dupuytren Teaching Hospital, Limoges, France.; Institut national de la santé et de la recherche médicale UMR 1092, University of Limoges, Limoges, France.
Dequin PF; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.; Service de Médecine Intensive et Réanimation, Centre Hospitalier Régional Universitaire, Tours, France.
Si-Tahar M; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.
Baranek T; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.
Paget C; Institut national de la santé et de la recherche médicale, Centre d'Etude des Pathologies Respiratoires, UMR 1100, Tours, France.; Université de Tours, Faculté de Médecine de Tours, Tours, France.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2020 Dec 07; Vol. 217 (12).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phenotype*
Betacoronavirus/*genetics
Coronavirus Infections/*immunology
Mucosal-Associated Invariant T Cells/*metabolism
Natural Killer T-Cells/*metabolism
Pneumonia, Viral/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*metabolism
Respiratory Distress Syndrome, Adult/*immunology
Aged ; Antigens, CD/blood ; Antigens, Differentiation, T-Lymphocyte/blood ; Cells, Cultured ; Coronavirus Infections/virology ; Cytokines/metabolism ; Female ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Lectins, C-Type/blood ; Male ; Middle Aged ; Mucosal-Associated Invariant T Cells/immunology ; Natural Killer T-Cells/immunology ; Pandemics ; Pneumonia, Viral/virology ; Prognosis ; Prospective Studies ; Respiratory Distress Syndrome, Adult/virology ; Severity of Illness Index
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Cow milk exosomes activate NK cells and γδT cells in human PBMCs in vitro.
Autorzy :
Komine-Aizawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Ito S; Nihon University Itabashi Hospital, Tokyo, Japan.
Aizawa S; Department of Animal Science, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
Namiki T; Nihon University School of Medicine, Tokyo, Japan.
Hayakawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
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Źródło :
Immunological medicine [Immunol Med] 2020 Dec; Vol. 43 (4), pp. 161-170. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphocyte Activation*
Exosomes/*immunology
Exosomes/*physiology
Killer Cells, Natural/*immunology
Leukocytes, Mononuclear/*immunology
Milk/*cytology
T-Lymphocytes/*immunology
Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Cells, Cultured ; Cytokines/metabolism ; Flow Cytometry ; Humans ; Interferon-gamma/metabolism ; Interleukin-12/immunology ; Interleukin-2/immunology ; Killer Cells, Natural/metabolism ; Lectins, C-Type/metabolism ; Leukocytes, Mononuclear/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
COVID-19: Cytokine storm modulation/blockade with oral polyvalent immunoglobulins (PVIG, KMP01D): A potential and safe therapeutic agent ( Primum nil nocere ).
Autorzy :
Sly LM
Braun P
Woodcock BG
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Źródło :
International journal of clinical pharmacology and therapeutics [Int J Clin Pharmacol Ther] 2020 Dec; Vol. 58 (12), pp. 678-686.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*therapy
Cytokine Release Syndrome/*therapy
Pneumonia, Viral/*therapy
Animals ; Betacoronavirus ; Cattle ; Cells, Cultured ; Cytokine Release Syndrome/virology ; Cytokines ; Humans ; Immunization, Passive ; Immunoglobulins, Intravenous/therapeutic use ; Leukocytes, Mononuclear ; Pandemics
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Maternal exposure to Di-n-butyl phthalate (DBP) aggravate gestational diabetes mellitus via FoxM1 suppression by pSTAT1 signalling.
Autorzy :
Chen M; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Zhao S; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Guo WH; Pathology Center, Shanghai General Hospital/Faculty of Basic Medicine, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Zhu YP; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Pan L; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Xie ZW; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China.
Sun WL; Department of Geriatrics, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China. Electronic address: .
Jiang JT; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Dec 01; Vol. 205, pp. 111154. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*chemically induced
Diabetes, Gestational/*chemically induced
Dibutyl Phthalate/*toxicity
Endocrine Disruptors/*toxicity
Forkhead Box Protein M1/*metabolism
Maternal Exposure/*adverse effects
STAT1 Transcription Factor/*metabolism
Animals ; Cells, Cultured ; Diabetes Mellitus, Experimental/metabolism ; Diabetes, Gestational/metabolism ; Female ; Forkhead Box Protein M1/genetics ; Gene Expression/drug effects ; Humans ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Male ; Phosphorylation ; Pregnancy ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; STAT1 Transcription Factor/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
High neutralizing antibody titer in intensive care unit patients with COVID-19.
Autorzy :
Liu L; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
To KK; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
Chan KH; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Wong YC; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Zhou R; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Kwan KY; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Fong CH; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Chen LL; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Choi CY; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Lu L; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Tsang OT; Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Leung WS; Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
To WK; Department of Pathology, Princess Margaret Hospital, Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Hung IF; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People's Republic of China.
Yuen KY; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
Chen Z; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2020 Dec; Vol. 9 (1), pp. 1664-1670.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Neutralizing/*blood
Antibodies, Viral/*blood
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Pneumonia, Viral/*immunology
Adult ; Aged ; Cells, Cultured ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pandemics
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Design, synthesis and anticancer activity of naphthoquinone derivatives.
Autorzy :
Shen XB; School of Pharmacy, Anhui Medical University, Hefei, PR China.; Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, Fuyang Normal University, Fuyang, PR China.
Wang Y; School of Pharmacy, Anhui Medical University, Hefei, PR China.
Han XZ; Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, Fuyang Normal University, Fuyang, PR China.
Sheng LQ; Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, Fuyang Normal University, Fuyang, PR China.
Wu FF; School of Pharmacy, Anhui Medical University, Hefei, PR China.; Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, Fuyang Normal University, Fuyang, PR China.
Liu X; School of Pharmacy, Anhui Medical University, Hefei, PR China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 773-785.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Antineoplastic Agents/*pharmacology
Naphthoquinones/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Naphthoquinones/chemical synthesis ; Naphthoquinones/chemistry ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Synthesis, activity and mechanism of alkoxy-, carbamato-, sulfonamido-, thioureido-, and ureido-derivatives of 2,4,5-trimethylpyridin-3-ol against inflammatory bowel disease.
Autorzy :
Chaudhary CL; College of Pharmacy and Institute for Drug Research, Yeungnam University , Gyeongsan , Republic of Korea.
Gurung P; College of Pharmacy and Institute for Drug Research, Yeungnam University , Gyeongsan , Republic of Korea.
Jang S; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University , Ansan , Republic of Korea.
Banskota S; College of Pharmacy and Institute for Drug Research, Yeungnam University , Gyeongsan , Republic of Korea.
Nam TG; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University , Ansan , Republic of Korea.
Kim JA; College of Pharmacy and Institute for Drug Research, Yeungnam University , Gyeongsan , Republic of Korea.
Jeong BS; College of Pharmacy and Institute for Drug Research, Yeungnam University , Gyeongsan , Republic of Korea.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1-20.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Inflammatory Bowel Diseases/*drug therapy
Pyridines/*pharmacology
Animals ; Anti-Inflammatory Agents/chemical synthesis ; Anti-Inflammatory Agents/chemistry ; Cells, Cultured ; Colitis/chemically induced ; Colitis/drug therapy ; Cytokines/antagonists & inhibitors ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Female ; HT29 Cells ; Humans ; Inflammatory Bowel Diseases/pathology ; Molecular Structure ; Pyridines/chemical synthesis ; Pyridines/chemistry ; Rats ; Rats, Sprague-Dawley ; Structure-Activity Relationship ; Trinitrobenzenesulfonic Acid ; U937 Cells
Czasopismo naukowe
Tytuł :
Examination of sulfonamide-based inhibitors of MMP3 using the conditioned media of invasive glioma cells.
Autorzy :
Poole AT; Department of Chemistry, Brandon University, Brandon, Canada.
Sitko CA; Department of Chemistry, Brandon University, Brandon, Canada.
Le C; Department of Chemistry, Brandon University, Brandon, Canada.
Naus CC; Department of Cellular and Physiological Sciences, University of British Columbia, Life Science Institute, Vancouver, Canada.
Hill BM; Department of Chemistry, Brandon University, Brandon, Canada.
Bushnell EAC; Department of Chemistry, Brandon University, Brandon, Canada.
Chen VC; Department of Chemistry, Brandon University, Brandon, Canada.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 672-681.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Brain Neoplasms/*drug therapy
Glioblastoma/*drug therapy
Matrix Metalloproteinase 3/*metabolism
Matrix Metalloproteinase Inhibitors/*pharmacology
Sulfonamides/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Matrix Metalloproteinase Inhibitors/chemical synthesis ; Matrix Metalloproteinase Inhibitors/chemistry ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer.
Autorzy :
Ruzzolini J; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Laurenzana A; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Andreucci E; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Peppicelli S; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Bianchini F; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Carta F; Department of NEUROFARBA, University of Florence, Florence, Italy.
Supuran CT; Department of NEUROFARBA, University of Florence, Florence, Italy.
Romanelli MN; Department of NEUROFARBA, University of Florence, Florence, Italy.
Nediani C; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.
Calorini L; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.; Center of Excellence for Research, Transfer and High Education, DenoTHE University of Florence, Florence, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 391-397.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*pharmacology
Histone Deacetylase Inhibitors/*pharmacology
Histone Deacetylases/*metabolism
Phenylurea Compounds/*pharmacology
Sulfonamides/*pharmacology
Antigens, Neoplasm/metabolism ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Histone Deacetylase Inhibitors/chemical synthesis ; Histone Deacetylase Inhibitors/chemistry ; Humans ; Molecular Structure ; Phenylurea Compounds/chemical synthesis ; Phenylurea Compounds/chemistry ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
IGFBP5 enhances the dentinogenesis potential of dental pulp stem cells via JNK and ErK signalling pathways.
Autorzy :
Hao J; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.; Department of Endodontics, Capital Medical University School of Stomatology, Beijing, China.
Yang H; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.
Cao Y; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.
Zhang C; Department of Endodontics, Capital Medical University School of Stomatology, Beijing, China.
Fan Z; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.
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Źródło :
Journal of oral rehabilitation [J Oral Rehabil] 2020 Dec; Vol. 47 (12), pp. 1557-1565. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Osteogenesis*
Animals ; Cell Differentiation ; Cells, Cultured ; Dental Pulp ; Dentinogenesis ; Humans ; Mice ; Mice, Nude ; Stem Cells
Czasopismo naukowe
Tytuł :
Comet assay protocol for Bombus atratus fat body and pericardial cells (Hymenoptera, bombini) at a safe concentration of mercury.
Autorzy :
Ceschi-Bertoli L; Postgraduate Program in Biotechnology and Environmental Monitoring, Federal University of São Carlos, UFSCar, Sorocaba, Brazil; Department of Biology, Laboratory of Structural and Functional Biology (LABEF), Federal University of São Carlos, UFSCar, Sorocaba, SP, Brazil.
Vidal FAP; Postgraduate Program in Biotechnology and Environmental Monitoring, Federal University of São Carlos, UFSCar, Sorocaba, Brazil; Department of Biology, Laboratory of Structural and Functional Biology (LABEF), Federal University of São Carlos, UFSCar, Sorocaba, SP, Brazil.
Balsamo PJ; Postgraduate Program in Biotechnology and Environmental Monitoring, Federal University of São Carlos, UFSCar, Sorocaba, Brazil; Department of Biology, Laboratory of Structural and Functional Biology (LABEF), Federal University of São Carlos, UFSCar, Sorocaba, SP, Brazil.
Abdalla FC; Postgraduate Program in Biotechnology and Environmental Monitoring, Federal University of São Carlos, UFSCar, Sorocaba, Brazil; Department of Biology, Laboratory of Structural and Functional Biology (LABEF), Federal University of São Carlos, UFSCar, Sorocaba, SP, Brazil. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 261, pp. 127752. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Bees/*drug effects
Environmental Pollutants/*toxicity
Fat Body/*drug effects
Mercury/*toxicity
Pericardium/*drug effects
Animals ; Bees/genetics ; Bees/growth & development ; Brazil ; Cells, Cultured ; Comet Assay/methods ; Fat Body/pathology ; Pericardium/pathology
Czasopismo naukowe
Tytuł :
Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity.
Autorzy :
Xu L; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Zhao Q; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Luo J; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Ma W; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Jin Y; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Li C; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Hou Y; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Feng M; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Wang Y; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Chen J; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Zhao J; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China.
Zheng Y; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China. Electronic address: .
Yu D; Department of Toxicology, School of Public Health, Qingdao University, Qingdao, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Dec 01; Vol. 205, pp. 111166. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical and Drug Induced Liver Injury/*metabolism
Dimethylformamide/*toxicity
Environmental Pollutants/*toxicity
Hepatocytes/*drug effects
Lipid Metabolism/*drug effects
Metabolome/*drug effects
Proteome/*metabolism
Animals ; Cell Survival/drug effects ; Cells, Cultured ; Endoplasmic Reticulum Stress/drug effects ; Glutathione/metabolism ; Hepatocytes/metabolism ; Humans ; Lipidomics ; Metabolomics ; Primary Cell Culture ; Proteomics ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Toxicity Tests/methods
Czasopismo naukowe
Tytuł :
Stem-like cells of various origins showed therapeutic effect to improve the recovery of spinal cord injury.
Autorzy :
Kang J; Department of Orthopedics, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Zhang C; Department of Orthopedics, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Zhi Z; Department of Orthopedics, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Wang Y; Department of Orthopedics, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Liu J; Department of Orthopedics, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Wu F; Shanghai Clinical Research Center for Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Xu G; Department of Orthopedics, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 627-638.
Typ publikacji :
Journal Article
MeSH Terms :
Exosomes/*transplantation
MicroRNAs/*genetics
Spinal Cord Injuries/*therapy
Stem Cells/*metabolism
Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Caspase 3/genetics ; Caspase 3/metabolism ; Cells, Cultured ; Culture Media, Conditioned/metabolism ; Culture Media, Conditioned/pharmacology ; Exosomes/genetics ; Exosomes/metabolism ; Gene Expression Regulation ; Humans ; Locomotion/physiology ; Male ; Neuroepithelial Cells/cytology ; Neuroepithelial Cells/metabolism ; Neurons/metabolism ; Neurons/pathology ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction ; Spinal Cord Injuries/pathology ; Spinal Cord Injuries/physiopathology ; Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle.
Autorzy :
Takaishi K; Department of Dental Anesthesiology, Tokushima University Hospital, Tokushima, Japan.
Kinoshita H; Department of Anesthesiology, Tokushima University Hospital, Tokushima, Japan; Department of Anesthesiology, Aichi Medical University School of Medicine, Aichi, Japan. Electronic address: .
Feng GG; Department of Anesthesiology, Aichi Medical University School of Medicine, Aichi, Japan.
Azma T; Department of Anesthesiology & Pain Medicine, Kohnodai Hospital, National Center for Global Health and Medicine, Ichikawa, Japan.
Kawahito S; Department of Anesthesiology, Tokushima University Hospital, Tokushima, Japan.
Kitahata H; Department of Dental Anesthesiology, Tokushima University Hospital, Tokushima, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Dec; Vol. 144 (4), pp. 197-203. Date of Electronic Publication: 2020 Aug 23.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochalasin B/*pharmacology
Cytoskeleton/*metabolism
Glucose/*adverse effects
Hyperglycemia/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Oxidative Stress/*drug effects
Adult ; Aged ; Cells, Cultured ; Cromakalim/pharmacology ; Female ; Humans ; Hyperglycemia/physiopathology ; In Vitro Techniques ; Male ; Middle Aged ; Muscle Relaxation/drug effects ; NADPH Oxidases/metabolism ; Superoxides/metabolism
Czasopismo naukowe

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