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Wyszukujesz frazę ""Cells, Cultured"" wg kryterium: Temat


Tytuł :
Mind your media.
Autorzy :
Lagziel S; Faculty of Computer Science, Technion, Haifa, Israel.
Gottlieb E; Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel. .
Shlomi T; Faculty of Computer Science, Technion, Haifa, Israel. .; Faculty of Biology, Technion, Haifa, Israel. .; Lokey Center for Life Science and Engineering, Technion, Haifa, Israel. .
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Źródło :
Nature metabolism [Nat Metab] 2020 Dec; Vol. 2 (12), pp. 1369-1372.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cells, Cultured*
Culture Media*
Animals ; Cell Line, Tumor ; Humans ; Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Mathematical modelling reveals cellular dynamics within tumour spheroids.
Autorzy :
Bull JA; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Mech F; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Quaiser T; Roche Pharma Research and Early Development, pRED Informatics, Roche Innovation Centre Munich, Germany.
Waters SL; Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Byrne HM; Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Aug 18; Vol. 16 (8), pp. e1007961. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Spheroids, Cellular*/cytology
Spheroids, Cellular*/physiology
Tumor Cells, Cultured*/cytology
Tumor Cells, Cultured*/physiology
Animals ; Biomechanical Phenomena ; Cell Death/physiology ; Cell Hypoxia/physiology ; Cell Proliferation/physiology ; Computational Biology ; Humans
Czasopismo naukowe
Tytuł :
Measurement and visualization of cell membrane surface charge in fixed cultured cells related with cell morphology.
Autorzy :
Nishino M; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Matsuzaki I; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Musangile FY; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Takahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Iwahashi Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Warigaya K; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kinoshita Y; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Kojima F; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
Murata SI; Department of Human Pathology, Wakayama Medical University, Wakayama, Japan.
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Źródło :
PloS one [PLoS One] 2020 Jul 23; Vol. 15 (7), pp. e0236373. Date of Electronic Publication: 2020 Jul 23 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Cytodiagnosis*
Cell Line/*ultrastructure
Cell Membrane/*ultrastructure
Cells, Cultured/*ultrastructure
Anaphase/drug effects ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Division/drug effects ; Cell Membrane/drug effects ; Cells, Cultured/drug effects ; Fixatives/pharmacology ; Humans ; Membrane Potentials/drug effects ; Pepsin A/pharmacology ; Surface Properties
Czasopismo naukowe
Tytuł :
Supervised Machine Learning Algorithms for Bioelectromagnetics: Prediction Models and Feature Selection Techniques Using Data from Weak Radiofrequency Radiation Effect on Human and Animals Cells.
Autorzy :
Halgamuge MN; Department of Electrical and Electronic Engineering, The University of Melbourne, Parkville, VIC 3010, Australia.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Jun 26; Vol. 17 (12). Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Cells, Cultured*/radiation effects
Radio Waves*/adverse effects
Supervised Machine Learning*
Animals ; Area Under Curve ; Humans
Czasopismo naukowe
Tytuł :
BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION.
Autorzy :
Kobayashi A; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Autsavapromporn N; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Therapeutic Radiology and Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Thailand.
Ahmad TAFT; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.; Division of Agrotechnology and Biosciences, Malaysian Nuclear Agency, Bangi, Kajang, Malaysia.
Oikawa M; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Homma-Takeda S; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Furusawa Y; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
Wang J; Key Laboratory of Ion Beam Bioengineering, Hefei Institute of Physical Science, Chinese Academy of Sciences and Anhui Province, No. 350 of Shushanhu Road, Hefei, PR China.
Konishi T; SPICE-BIO research core, International Open Laboratory, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, Chiba, Japan.
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Źródło :
Radiation protection dosimetry [Radiat Prot Dosimetry] 2019 May 01; Vol. 183 (1-2), pp. 142-146.
Typ publikacji :
Journal Article
MeSH Terms :
A549 Cells/*radiation effects
Cell Communication/*radiation effects
DNA Breaks, Double-Stranded/*radiation effects
Gap Junctions/*radiation effects
Lung Neoplasms/*radiotherapy
Tumor Cells, Cultured/*radiation effects
Bystander Effect/radiation effects ; Cells, Cultured/radiation effects ; Coculture Techniques ; DNA Repair ; Fibroblasts/radiation effects ; Histones/analysis ; Humans ; Protons
Czasopismo naukowe
Tytuł :
Quietness of circular RNA circ_0054633 alleviates the inflammation and proliferation in lipopolysaccharides-induced acute lung injury model through NF-κB signaling pathway.
Autorzy :
Yang CL; Department of Critical Care Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, JiangXi, China.
Yang WK; Department of Cardiovascular Surgery, Central People's Hospital of Zhanjiang, Zhanjiang, GuangDong, China.
He ZH; Department of Critical Care Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, JiangXi, China.
Guo JH; Department of Critical Care Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, JiangXi, China.
Yang XG; Department of Critical Care Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, JiangXi, China.
Li HB; Department of Orthopaedics, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, JiangXi 330006, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 15; Vol. 766, pp. 145153. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Lung Injury/*metabolism
Cell Proliferation/*physiology
Endothelial Cells/*metabolism
Inflammation/*metabolism
NF-kappa B/*metabolism
RNA, Circular/*metabolism
Acute Lung Injury/chemically induced ; Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Cell Proliferation/drug effects ; Cells, Cultured ; Inflammation/chemically induced ; Interleukin-17/metabolism ; Lipopolysaccharides/pharmacology ; Lung/drug effects ; Lung/metabolism ; Male ; Mice ; Rats ; Rats, Sprague-Dawley ; Transcription Factor RelA/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Circular RNA Arhgap12 modulates doxorubicin-induced cardiotoxicity by sponging miR-135a-5p.
Autorzy :
Wang X; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Cheng Z; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Xu J; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Feng M; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Zhang H; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Zhang L; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: .
Qian L; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of General Medicine, Tongren Hospital of Shanghai Jiao Tong University of Medicine, Shanghai 200336, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118788. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*toxicity
Cardiotoxicity/*metabolism
Doxorubicin/*toxicity
GTPase-Activating Proteins/*biosynthesis
MicroRNAs/*biosynthesis
RNA, Circular/*biosynthesis
Animals ; Cardiotoxicity/genetics ; Cells, Cultured ; GTPase-Activating Proteins/genetics ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; RNA, Circular/genetics ; Random Allocation ; Rats
Czasopismo naukowe
Tytuł :
Hypoxic conditioned promotes the proliferation of human olfactory mucosa mesenchymal stem cells and relevant lncRNA and mRNA analysis.
Autorzy :
He J; Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Huang Y; National Health Commission Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha 410008, Hunan, PR China; Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, PR China; Hunan Provincial Key Laboratory of Neurorestoratology, Second Affiliated Hospital of Hunan Normal University, Changsha 410003, Hunan, PR China.
Liu J; Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Ge L; Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Tang X; Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Lu M; Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, PR China; Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University, Changsha 410003, Hunan, PR China; Hunan Provincial Key Laboratory of Neurorestoratology, Second Affiliated Hospital of Hunan Normal University, Changsha 410003, Hunan, PR China. Electronic address: .
Hu Z; Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118861. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*physiology
Mesenchymal Stem Cells/*cytology
Olfactory Mucosa/*cytology
RNA, Long Noncoding/*genetics
RNA, Messenger/*genetics
Apoptosis/physiology ; Cell Hypoxia/physiology ; Cells, Cultured ; Gene Expression Regulation ; Humans ; MicroRNAs/genetics
Czasopismo naukowe
Tytuł :
Sirt1 attenuates diabetic keratopathy by regulating the endoplasmic reticulum stress pathway.
Autorzy :
Wei S; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China.
Fan J; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China.
Zhang X; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China.
Jiang Y; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China.
Zeng S; Department of Rehabilitation Therapy, Shanghai Normal University Tianhua College, Shanghai 201815, China.
Pan X; Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200123, China. Electronic address: .
Sheng M; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China. Electronic address: .
Chen Y; Department of Ophthalmology, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118789. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Corneal Diseases/*metabolism
Diabetes Mellitus, Experimental/*metabolism
Endoplasmic Reticulum Stress/*physiology
Sirtuin 1/*biosynthesis
Animals ; Cells, Cultured ; Corneal Diseases/genetics ; Corneal Diseases/pathology ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/pathology ; Epithelial Cells/metabolism ; Female ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Sirtuin 1/genetics
Czasopismo naukowe
Tytuł :
Effect of mechanical injury and IL-1β on the expression of LOXs and MMP-1, 2, 3 in PCL fibroblasts after co-culture with synoviocytes.
Autorzy :
Xu C; '111' Project Laboratory of Biomechanics and Tissue Repair, Bioengineering College, Chongqing University, Chongqing, China.
Chi Q; '111' Project Laboratory of Biomechanics and Tissue Repair, Bioengineering College, Chongqing University, Chongqing, China; Department of Mechanics and Engineering Structure, Wuhan University of Technology, China.
Yang L; '111' Project Laboratory of Biomechanics and Tissue Repair, Bioengineering College, Chongqing University, Chongqing, China.
Paul Sung KL; '111' Project Laboratory of Biomechanics and Tissue Repair, Bioengineering College, Chongqing University, Chongqing, China; Departments of Bioengineering and Orthopedics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0412, United States. Electronic address: .
Wang C; '111' Project Laboratory of Biomechanics and Tissue Repair, Bioengineering College, Chongqing University, Chongqing, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 15; Vol. 766, pp. 145149. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Fibroblasts/*metabolism
Interleukin-1beta/*metabolism
Matrix Metalloproteinases/*metabolism
Protein-Lysine 6-Oxidase/*metabolism
Synoviocytes/*metabolism
Cells, Cultured ; Coculture Techniques/methods ; Extracellular Matrix/metabolism ; Humans ; Synovial Membrane/metabolism ; Wound Healing/physiology
Czasopismo naukowe
Tytuł :
MiR-140-5p/TLR4 /NF-κB signaling pathway: Crucial role in inflammatory response in 16HBE cells induced by dust fall PM 2.5 .
Autorzy :
Chen X; Department of Laboratory Medicine, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Deng T; Southwest University of Science and Technology, Mianyang 621010, China.
Huo T; Southwest University of Science and Technology, Mianyang 621010, China.
Dong F; Southwest University of Science and Technology, Mianyang 621010, China. Electronic address: .
Deng J; Department of Laboratory Medicine, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China; Sichuan Mianyang 404 Hospital, Mianyang 621000, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111414. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji :
Journal Article
MeSH Terms :
NF-kappa B/*metabolism
Particulate Matter/*toxicity
Cells, Cultured ; Dust ; Humans ; Inflammation ; Lipopolysaccharides ; MicroRNAs/genetics ; Signal Transduction/drug effects ; Toll-Like Receptor 4/metabolism ; Transcription Factor RelA
Czasopismo naukowe
Tytuł :
Cadmium-stimulated invasion of rat liver cells during malignant transformation: Evidence of the involvement of oxidative stress/TET1-sensitive machinery.
Autorzy :
Hirao-Suzuki M; Laboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University (HIU), 5-1-1 Hiro-koshingai, Kure, Hiroshima, 737-0112, Japan.
Takeda S; Laboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University (HIU), 5-1-1 Hiro-koshingai, Kure, Hiroshima, 737-0112, Japan; Laboratory of Molecular Life Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzou 1, Gakuen-cho, Fukuyama, Hiroshima, 729-0292, Japan. Electronic address: .
Sakai G; Laboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University (HIU), 5-1-1 Hiro-koshingai, Kure, Hiroshima, 737-0112, Japan; Laboratory of Molecular Life Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzou 1, Gakuen-cho, Fukuyama, Hiroshima, 729-0292, Japan.
Waalkes MP; Raleigh, NC, 27709, USA.
Sugihara N; Laboratory of Molecular Life Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Sanzou 1, Gakuen-cho, Fukuyama, Hiroshima, 729-0292, Japan.
Takiguchi M; Laboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University (HIU), 5-1-1 Hiro-koshingai, Kure, Hiroshima, 737-0112, Japan. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2021 Jan 15; Vol. 447, pp. 152631. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadmium/*toxicity
Dioxygenases/*antagonists & inhibitors
Dioxygenases/*biosynthesis
Liver/*drug effects
Liver/*metabolism
Oxidative Stress/*drug effects
Animals ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cells, Cultured ; DNA Methylation/drug effects ; DNA Methylation/physiology ; Dose-Response Relationship, Drug ; Liver/pathology ; Neoplasm Invasiveness/pathology ; Oxidative Stress/physiology ; Rats ; Rats, Inbred F344
Czasopismo naukowe
Tytuł :
Control of preadipocyte proliferation, apoptosis and early adipogenesis by the forkhead transcription factor FoxO6.
Autorzy :
Abdalla BA; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Chen X; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Li K; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Chen J; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Yi Z; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Zhang X; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China.
Li Z; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China. Electronic address: .
Nie Q; College of Animal Science & Lingnan Guangdong Laboratory of Modern Agriculture, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou 510642, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118858. Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article
MeSH Terms :
Adipocytes/*metabolism
Adipogenesis/*genetics
Apoptosis/*genetics
Cell Proliferation/*genetics
Forkhead Transcription Factors/*genetics
Adipocytes/cytology ; Animals ; Cells, Cultured ; Chickens ; Chromatin Immunoprecipitation ; Cyclin G2/genetics ; Female ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Knockdown Techniques ; Male ; PPAR gamma/metabolism
Czasopismo naukowe
Tytuł :
Ctnnb1 transcriptional upregulation compensates for Mdm2/p53-mediated β-catenin degradation in neutrophils following cardioembolic stroke.
Autorzy :
Wang H; Department of Cardiovascular Medicine, Chongqing University Central Hospital, Chongqing 400014, China.
Zhou K; Department of Cardiovascular Medicine, Chongqing University Central Hospital, Chongqing 400014, China.
Li W; Department of Pulmonary and Critical Care Medicine, Chongqing Seventh People's Hospital, Chongqing 400054, China.
Du J; Department of Cardiology, Chongqing Medical University Second Affiliated Hospital, Chongqing 400010, China.
Xiao J; Department of Cardiovascular Medicine, Chongqing University Central Hospital, Chongqing 400014, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 15; Vol. 766, pp. 145022. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Neutrophils/*metabolism
Proto-Oncogene Proteins c-mdm2/*genetics
Stroke/*genetics
Stroke/*metabolism
Tumor Suppressor Protein p53/*genetics
Up-Regulation/*genetics
beta Catenin/*genetics
Animals ; Cells, Cultured ; Down-Regulation/genetics ; Gene Expression/genetics ; Gene Regulatory Networks/genetics ; Heart/physiopathology ; Humans ; Leukocytes, Mononuclear/metabolism ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Transcription, Genetic/genetics ; Transcriptional Activation/genetics
Czasopismo naukowe
Tytuł :
The PKC-ζ pseudosubstrate peptide induces glutamate release from retinal pigment epithelium cells through kinase- independent activation of Best1.
Autorzy :
Lee-Rivera I; Department of Molecular Neuropathology, Instituto de Fisiología Celular, UNAM, Apartado Postal 70-253, Ciudad Universitaria, México City, CdMx, Mexico.
López E; Department of Molecular Neuropathology, Instituto de Fisiología Celular, UNAM, Apartado Postal 70-253, Ciudad Universitaria, México City, CdMx, Mexico.
Alvarez-Arce A; Department of Molecular Neuropathology, Instituto de Fisiología Celular, UNAM, Apartado Postal 70-253, Ciudad Universitaria, México City, CdMx, Mexico.
López-Colomé AM; Department of Molecular Neuropathology, Instituto de Fisiología Celular, UNAM, Apartado Postal 70-253, Ciudad Universitaria, México City, CdMx, Mexico. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118860. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
Bestrophins/*metabolism
Glutamic Acid/*metabolism
Peptides/*pharmacology
Protein Kinase C/*antagonists & inhibitors
Retinal Pigment Epithelium/*metabolism
Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Peptides/administration & dosage ; Rats ; Rats, Long-Evans ; Retinal Pigment Epithelium/cytology
Czasopismo naukowe
Tytuł :
Increased expression of hras induces early, but not full, senescence in the immortal fish cell line, EPC.
Autorzy :
Futami K; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan. Electronic address: .
Aoyama K; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
Fukuda K; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
Maita M; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
Katagiri T; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
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Źródło :
Gene [Gene] 2021 Jan 10; Vol. 765, pp. 145116. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Cellular Senescence/*genetics
Genes, ras/*genetics
Genes, ras/*physiology
Aging/genetics ; Aging/metabolism ; Animals ; Cell Line ; Cells, Cultured ; Cellular Senescence/physiology ; Fishes/genetics ; Humans ; Proto-Oncogene Proteins p21(ras)/genetics
Czasopismo naukowe
Tytuł :
Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2.
Autorzy :
Li F; Institute for Informatics (I2), Washington University in St. Louis School of Medicine, St. Louis, MO, USA. .; Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. .
Michelson AP; Institute for Informatics (I2), Washington University in St. Louis School of Medicine, St. Louis, MO, USA.; Pulmonary and Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Foraker R; Institute for Informatics (I2), Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Zhan M; National Institute of Mental Health (NIMH), NIH, Bethesda, MD, USA.
Payne PRO; Institute for Informatics (I2), Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
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Źródło :
BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2021 Jan 07; Vol. 21 (1), pp. 15. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Repositioning*
Pharmaceutical Preparations*
Signal Transduction*
Transcription, Genetic*
COVID-19/*drug therapy
Cells, Cultured ; Epithelial Cells/virology ; Gene Ontology ; Humans ; SARS-CoV-2/drug effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Evolution, expression profile, and regulatory characteristics of ACSL gene family in chicken (Gallus gallus).
Autorzy :
Tian W; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Wang D; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Wang Z; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Jiang K; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Li Z; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; Henan Innovative Engineering Research Center of Poultry Germplasm Resource, Zhengzhou 450002, China; International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450002, China.
Tian Y; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; Henan Innovative Engineering Research Center of Poultry Germplasm Resource, Zhengzhou 450002, China; International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450002, China.
Kang X; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; Henan Innovative Engineering Research Center of Poultry Germplasm Resource, Zhengzhou 450002, China; International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450002, China.
Liu X; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; Henan Innovative Engineering Research Center of Poultry Germplasm Resource, Zhengzhou 450002, China; International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450002, China. Electronic address: .
Li H; College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China; Henan Innovative Engineering Research Center of Poultry Germplasm Resource, Zhengzhou 450002, China; International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450002, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 05; Vol. 764, pp. 145094. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Chickens/*genetics
Coenzyme A Ligases/*genetics
Lipid Metabolism/*genetics
Multigene Family/*genetics
Acyl Coenzyme A/metabolism ; Animals ; Cells, Cultured ; Chick Embryo ; Chickens/growth & development ; Chickens/metabolism ; Coenzyme A Ligases/metabolism ; Computational Biology ; Estrogens/metabolism ; Fatty Acids/metabolism ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Hepatocytes ; Primary Cell Culture ; Protein Domains/genetics ; Spatio-Temporal Analysis ; Synteny
Czasopismo naukowe
Tytuł :
Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition.
Autorzy :
Zhou L; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
He R; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Fang P; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Li M; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Yu H; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Wang Q; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, China.
Yu Y; The Key Laboratory of Biosystems Homeostasis and Protection of the Ministry of Education and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Wang F; Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhang Y; Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, College of Food and Pharmaceutical Engineering, Hubei University of Technology, Wuhan, 430068, China.
Chen A; Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Peng N; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Lin Y; The Key Laboratory of Molecular Biology of Infectious Diseases designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Zhang R; Department of Hepato-Pancreato-Biliary Surgery, SunYat-sen Memorial Hospital, SunYat-sen University, Guangzhou, 510120, China.
Trilling M; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, 45122, Germany.
Broering R; Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, 45122, Germany.
Lu M; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, 45122, Germany.
Zhu Y; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Liu S; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 98. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*
Metabolome*
Hepatitis B virus/*physiology
Adaptor Proteins, Signal Transducing/metabolism ; Anaerobiosis ; Animals ; Cells, Cultured ; DEAD Box Protein 58/metabolism ; Glucose/metabolism ; Glycolysis ; Hep G2 Cells ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Hepatocytes/virology ; Humans ; Immune Evasion ; Interferons/metabolism ; Lactic Acid/metabolism ; Mice, Inbred C57BL ; Models, Biological ; Signal Transduction ; Virion/metabolism
Czasopismo naukowe
Tytuł :
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH.
Autorzy :
Dong J; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Viswanathan S; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Adami E; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Singh BK; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Chothani SP; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Ng B; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Lim WW; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Zhou J; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Tripathi M; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Ko NSJ; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Shekeran SG; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Tan J; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Lim SY; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Wang M; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Lio PM; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Yen PM; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.
Schafer S; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Cook SA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore. .; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore. .; National Heart and Lung Institute, Imperial College London, London, UK. .; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, UK. .
Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 66. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*/drug effects
Hepatocytes/*metabolism
Interleukin-11/*metabolism
Lipids/*toxicity
Non-alcoholic Fatty Liver Disease/*metabolism
Non-alcoholic Fatty Liver Disease/*pathology
Adult ; Animals ; Autocrine Communication/drug effects ; Cells, Cultured ; Disease Models, Animal ; Feeding Behavior ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Hepatic Stellate Cells/pathology ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Humans ; Interleukin-11 Receptor alpha Subunit/metabolism ; Interleukin-6/metabolism ; Mice, Knockout ; Models, Biological ; Paracrine Communication/drug effects ; Phenotype
Czasopismo naukowe

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