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Wyszukujesz frazę ""Cellular Senescence"" wg kryterium: Temat


Tytuł:
Exploring the emerging bidirectional association between inflamm-aging and cellular senescence in organismal aging and disease.
Autorzy:
Sharma R; Nutrigerontology Laboratory, Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, India.
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Źródło:
Cell biochemistry and function [Cell Biochem Funct] 2024 Mar; Vol. 42 (2), pp. e3970.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aging*
Cellular Senescence*
Inflammation*
Humans ; Immune System
Czasopismo naukowe
Tytuł:
Therapeutic effect of dietary ingredients on cellular senescence in animals and humans: A systematic review.
Autorzy:
Guan L; Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Centre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore.
Eisenmenger A; Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Centre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore.
Crasta KC; Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Centre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore; Department of Physiology, National University of Singapore, Singapore; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Agency for Science, Technology & Research (A⁎STAR), Institute of Molecular and Cell Biology (IMCB), Singapore.
Sandalova E; Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Centre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore.
Maier AB; Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Centre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore; Department of Human Movement Sciences, @AgeAmsterdam, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, the Netherlands. Electronic address: .
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Źródło:
Ageing research reviews [Ageing Res Rev] 2024 Mar; Vol. 95, pp. 102238. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Soybean Proteins*/pharmacology
Cellular Senescence*
Animals ; Humans ; Resveratrol ; Systematic Reviews as Topic ; Diet ; Vitamin E/pharmacology
Czasopismo naukowe
Tytuł:
Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence.
Autorzy:
Mahoney SA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Venkatasubramanian R; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Darrah MA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Ludwig KR; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
VanDongen NS; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Greenberg NT; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Longtine AG; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Hutton DA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Brunt VE; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Campisi J; Buck Institute for Research on Aging, Novato, California, USA.; Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Melov S; Buck Institute for Research on Aging, Novato, California, USA.
Seals DR; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Rossman MJ; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Clayton ZS; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
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Źródło:
Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14060. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/genetics
Arteries*
Flavonols*
Mice ; Humans ; Animals ; Dietary Supplements ; Inflammation
Czasopismo naukowe
Tytuł:
Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution.
Autorzy:
Taherian Fard A; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Leeson HC; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Aguado J; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Pietrogrande G; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Power D; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Gómez-Inclán C; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Zheng H; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Nelson CB; Children's Medical Research Institute, University of Sydney, Westmead, Sydney, NSW, Australia.
Soheilmoghaddam F; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.; School of Chemical Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, St Lucia, Australia.
Glass N; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Dharmaratne M; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Watson ER; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Lu J; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.
Martin S; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, St Lucia, QLD, Australia.
Pickett HA; Children's Medical Research Institute, University of Sydney, Westmead, Sydney, NSW, Australia.
Cooper-White J; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia.; School of Chemical Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, St Lucia, Australia.
Wolvetang EJ; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia. .
Mar JC; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia. .
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Źródło:
GeroScience [Geroscience] 2024 Feb; Vol. 46 (1), pp. 999-1015. Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/physiology
Mesenchymal Stem Cells*/metabolism
Humans
Czasopismo naukowe
Tytuł:
Ultrasensitive two-photon probes for rapid detection of β-galactosidase during fruit softening and cellular senescence.
Autorzy:
Shan YM; Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
Yu KK; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China. Electronic address: .
Yu FY; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 610064, China.
Liu YH; Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: .
Yu XQ; Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: .
Li K; Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China. Electronic address: .
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Źródło:
Food chemistry [Food Chem] 2024 Jan 15; Vol. 431, pp. 137117. Date of Electronic Publication: 2023 Aug 07.
Typ publikacji:
Journal Article
MeSH Terms:
Fruit*
Cellular Senescence*
Humans ; Animals ; beta-Galactosidase ; Fluorescent Dyes ; Lysosomes ; Mammals
Czasopismo naukowe
Tytuł:
Design and optimization of piperlongumine analogs as potent senolytics.
Autorzy:
Zhang X; Department of Medicinal Chemistry and University of Florida, Gainesville, FL, 32610, USA.
He Y; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, 32610, USA.
Liu X; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, 32610, USA.
Zhang X; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, 32610, USA.
Shi P; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, 72204, USA.
Wang Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, 72204, USA.
Zhou D; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, 32610, USA; Department of Biochemistry and Structure Biology, Center of Innovative Drug Discovery, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Zheng G; Department of Medicinal Chemistry and University of Florida, Gainesville, FL, 32610, USA. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jan 15; Vol. 98, pp. 129593. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*
Senotherapeutics*
Czasopismo naukowe
Tytuł:
Senescent cells at the crossroads of aging, disease, and tissue homeostasis.
Autorzy:
Kuehnemann C; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA.
Wiley CD; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA.
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Źródło:
Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e13988. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aging*/physiology
Cellular Senescence*/physiology
Humans ; Animals ; Mice ; Disease Models, Animal ; Senescence-Associated Secretory Phenotype ; Homeostasis
Czasopismo naukowe
Tytuł:
Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging.
Autorzy:
Zhou Z; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Yao J; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Wu D; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Huang X; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Wang Y; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Li X; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Lu Q; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Qiu Y; Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China. Electronic address: .
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Źródło:
Immunity [Immunity] 2024 Mar 12; Vol. 57 (3), pp. 513-527.e6. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-4*/metabolism
Cellular Senescence*
Animals ; Mice ; Aging/genetics ; Macrophages ; Inflammation
Czasopismo naukowe
Tytuł:
Mitochondria: A new member involved in stem cell senescence. An extended commentary on "Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approaches by Mas-Bargues C. [Free Radic. Biol. Med. (2023) Nov 1;208:657-671. doi:10.1016/j.freeradbiomed.2023.09.019].
Autorzy:
Alique M; Departamento de Biología de Sistemas, Universidad de Alcalá, Alcalá de Henares, 28871, Madrid, Spain; Spain/Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034, Madrid, Spain. Electronic address: .
Mas-Bargues C; Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable-Instituto de Salud Carlos III (CIBERFES-ISCIII), INCLIVA, 46010, Valencia, Spain.
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2024 Mar; Vol. 213, pp. 426-429. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Cellular Senescence*
Mitochondria*
Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
IUPHAR ECR review: The cGAS-STING pathway: Novel functions beyond innate immune and emerging therapeutic opportunities.
Autorzy:
He X; Institute of Clinical Pharmacology, Peking University First Hospital, Xueyuan Road 38, Haidian District, Beijing 100191, China; Department of Pharmacy, Peking University First Hospital, Xishiku Street, Xicheng District, Beijing 100034, China.
Wedn A; School of Medicine, University of Pittsburgh, 5051 Centre Avenue, Pittsburgh, PA, USA.
Wang J; Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Gu Y; Institute of Clinical Pharmacology, Peking University First Hospital, Xueyuan Road 38, Haidian District, Beijing 100191, China; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Xueyuan Road 38, Haidian District, Beijing 100191, China.
Liu H; Department of General Surgery, Peking University First Hospital, Xishiku Street, Xicheng District, Beijing 100034, China.
Zhang J; Institute of Clinical Pharmacology, Peking University First Hospital, Xueyuan Road 38, Haidian District, Beijing 100191, China; Department of Pharmacy, Peking University First Hospital, Xishiku Street, Xicheng District, Beijing 100034, China.
Lin Z; Institute of Systems Biomedicine, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Peking University Health Science Center, Beijing 100191, China.
Zhou R; Department of Clinical Pharmacology, The Second Affiliated Hospital of Anhui Medical University, Anhui 230601, China; Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven CT06519, USA. Electronic address: .
Pang X; Institute of Clinical Pharmacology, Peking University First Hospital, Xueyuan Road 38, Haidian District, Beijing 100191, China; Department of Pharmacy, Peking University First Hospital, Xishiku Street, Xicheng District, Beijing 100034, China. Electronic address: .
Cui Y; Institute of Clinical Pharmacology, Peking University First Hospital, Xueyuan Road 38, Haidian District, Beijing 100191, China; Department of Pharmacy, Peking University First Hospital, Xishiku Street, Xicheng District, Beijing 100034, China. Electronic address: .
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Źródło:
Pharmacological research [Pharmacol Res] 2024 Mar; Vol. 201, pp. 107063. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autophagy*
Cellular Senescence*
Cell Death ; Immunity, Innate ; Nucleotidyltransferases
Czasopismo naukowe
Tytuł:
Hypoxia-induced immortalization of primary cells depends on Tfcp2L1 expression.
Autorzy:
Otero-Albiol D; Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Seville, Spain.; CIBER de CANCER, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Santos-Pereira JM; Centro Andaluz de Biología del Desarrollo (CABD), Consejo Superior de Investigaciones Científicas/Universidad Pablo de Olavide, 41013, Seville, Spain.
Lucena-Cacace A; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Clemente-González C; Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Seville, Spain.; CIBER de CANCER, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Muñoz-Galvan S; Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Seville, Spain.; CIBER de CANCER, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Yoshida Y; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Carnero A; Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Seville, Spain. .; CIBER de CANCER, Instituto de Salud Carlos III (ISCIII), Madrid, Spain. .
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Źródło:
Cell death & disease [Cell Death Dis] 2024 Feb 28; Vol. 15 (2), pp. 177. Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*
Fibroblasts*/metabolism
Animals ; Mice ; Carcinogenesis/pathology ; Cell Transformation, Neoplastic/metabolism ; Cells, Cultured ; Hypoxia/metabolism
Czasopismo naukowe
Tytuł:
A double inducible cell ablation system for eliminating senescent astrocytes via apoptosis.
Autorzy:
Wang X; Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Deng Y; Key Laboratory of Endemic and Minority Disease, Ministry of Education/Key Laboratory of Molecular Biology/Translational Medicine Research Center, Guizhou Medical University, Guiyang, Guizhou, China.
Xiao Y; Key Laboratory of Endemic and Minority Disease, Ministry of Education/Key Laboratory of Molecular Biology/Translational Medicine Research Center, Guizhou Medical University, Guiyang, Guizhou, China.
Wang F; Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Tang Z; Key Laboratory of Endemic and Minority Disease, Ministry of Education/Key Laboratory of Molecular Biology/Translational Medicine Research Center, Guizhou Medical University, Guiyang, Guizhou, China.
Qi X; Key Laboratory of Endemic and Minority Disease, Ministry of Education/Key Laboratory of Molecular Biology/Translational Medicine Research Center, Guizhou Medical University, Guiyang, Guizhou, China. .; Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-Constructed By the Province and Ministry, Guiyang, Guizhou, China. .
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Źródło:
Molecular biology reports [Mol Biol Rep] 2024 Feb 26; Vol. 51 (1), pp. 363. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Cellular Senescence*/genetics
Humans ; Aging ; Tacrolimus Binding Proteins/chemistry ; Tacrolimus Binding Proteins/metabolism ; Apoptosis/genetics
Czasopismo naukowe
Tytuł:
WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.
Autorzy:
Zhou L; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Department of Dermatology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, P.R. China.
Zhong Y; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.
Wang F; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.
Guo Y; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.
Mao R; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.
Xie H; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.
Zhang Y; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China, 410008.
Li J; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, P.R. China.; Hunan key laboratory of aging biology, Xiangya Hospital, Central South University, Changsha, P.R. China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China, 410008.
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Źródło:
International journal of biological sciences [Int J Biol Sci] 2024 Feb 25; Vol. 20 (5), pp. 1763-1777. Date of Electronic Publication: 2024 Feb 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/genetics
Senescence-Associated Secretory Phenotype*
Humans ; Adenosine ; Cell Cycle Proteins ; DNA-Binding Proteins ; Interferon Regulatory Factors ; Proto-Oncogene Proteins c-ets ; RNA ; RNA Splicing Factors ; Transcription Factors
Czasopismo naukowe
Tytuł:
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors.
Autorzy:
Alessio N; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy.
Aprile D; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy.
Peluso G; International Medical University UNICAMILLUS, Rome, Italy.
Mazzone V; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy.
Patrone D; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy.
Di Bernardo G; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy. .
Galderisi U; Department of Experimental Medicine, Luigi Vanvitelli Campania University, via Luigi De Crecchio 7, Naples, 80138, Italy. .; Genome and Stem Cell Center (GENKÖK), Erciyes University, Kayseri, Turkey. .; Center for Biotechnology, Sbarro Institute for Cancer Research and Molecular Medicine Temple University, PA, Philadelphia, USA. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 13; Vol. 22 (1), pp. 122. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/genetics
Neoplasms*/metabolism
Humans ; Aging ; Cells, Cultured ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
Data-driven detection of age-related arbitrary monotonic changes in single-cell gene expression distributions.
Autorzy:
Cheng JH; Center for Genomics Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan.
Okada D; Center for Genomics Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan.
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Źródło:
PeerJ [PeerJ] 2024 Feb 08; Vol. 12, pp. e16851. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression*/genetics
Single-Cell Analysis*
Cellular Senescence*
Czasopismo naukowe
Tytuł:
Detection of senescence using machine learning algorithms based on nuclear features.
Autorzy:
Duran I; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Pombo J; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Sun B; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Gallage S; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; M3 Research Center for Malignome, Metabolome and Microbiome, Faculty of Medicine, University of Tuebingen, Otfried-Müller-Straße 37, 72076, Tübingen, Germany.
Kudo H; Section for Pathology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, W2 1NY, UK.
McHugh D; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Bousset L; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Barragan Avila JE; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Forlano R; Liver Unit, Section of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, W2 1NY, UK.
Manousou P; Liver Unit, Section of Hepatology and Gastroenterology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, W2 1NY, UK.
Heikenwalder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; M3 Research Center for Malignome, Metabolome and Microbiome, Faculty of Medicine, University of Tuebingen, Otfried-Müller-Straße 37, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180), Eberhard Karls University, Tübingen, Germany.
Withers DJ; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Vernia S; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
Goldin RD; Section for Pathology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, W2 1NY, UK.
Gil J; MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK. .; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 03; Vol. 15 (1), pp. 1041. Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:
Journal Article
MeSH Terms:
Aging*/physiology
Cellular Senescence*/physiology
Animals ; Mice ; Humans ; Fibrosis
Czasopismo naukowe
Tytuł:
Fisetin, a potential skin rejuvenation drug that eliminates senescent cells in the dermis.
Autorzy:
Takaya K; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. .
Asou T; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kishi K; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
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Źródło:
Biogerontology [Biogerontology] 2024 Feb; Vol. 25 (1), pp. 161-175. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/physiology
Rejuvenation*
Flavonols*
Animals ; Mice ; Humans ; Aged ; Mice, Nude ; Fibroblasts ; Collagen/metabolism ; Collagen/pharmacology ; Dermis/metabolism
Czasopismo naukowe
Tytuł:
Aging in the dermis: Fibroblast senescence and its significance.
Autorzy:
Zhang J; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin, China.
Yu H; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin, China.
Man MQ; Dermatology Hospital, Southern Medical University, Guangdong, China.; Department of Dermatology, University of California San Francisco and Veterans Affairs Medical Center, San Francisco, California, USA.
Hu L; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin, China.
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Źródło:
Aging cell [Aging Cell] 2024 Feb; Vol. 23 (2), pp. e14054. Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cellular Senescence*/physiology
Skin Aging*
Humans ; Fibroblasts/metabolism ; Dermis ; Inflammation/metabolism
Czasopismo naukowe
Tytuł:
The dual role of the DREAM/G2M pathway in non-tumorigenic immortalization of senescent cells.
Autorzy:
Tian J; Department of Pathophysiology, School of Basic Medicine, Guizhou Medical University, Guiyang, China.
Jiang L; Department of Pathophysiology, School of Basic Medicine, Guizhou Medical University, Guiyang, China.
Li H; School of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Dan J; Laboratory of Molecular Genetics of Aging & Tumor, Medical School, Kunming University of Science and Technology, China.
Luo Y; Department of Pathophysiology, School of Basic Medicine, Guizhou Medical University, Guiyang, China.
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Źródło:
FEBS open bio [FEBS Open Bio] 2024 Feb; Vol. 14 (2), pp. 331-343. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cellular Senescence*/genetics
Carcinogenesis*/genetics
Humans ; Cell Cycle ; Cell Line
Czasopismo naukowe

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