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Wyszukujesz frazę ""Cerebral cortex"" wg kryterium: Temat


Tytuł :
Effect of short-term oral supplementation of crocin on age-related oxidative stress, cholinergic, and mitochondrial dysfunction in rat cerebral cortex.
Autorzy :
Krishnaswamy VKD; Department of Biochemistry and Molecular Biology, Pondicherry University, India.
Alugoju P; Department of Biochemistry and Molecular Biology, Pondicherry University, India.
Periyasamy L; Department of Biochemistry and Molecular Biology, Pondicherry University, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118545. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*drug effects
Biomarkers/*metabolism
Carotenoids/*pharmacology
Cerebral Cortex/*drug effects
Cholinergic Agents/*pharmacology
Mitochondrial Diseases/*drug therapy
Oxidative Stress/*drug effects
Acetylcholine/metabolism ; Acetylcholinesterase/chemistry ; Administration, Oral ; Aging/metabolism ; Aging/pathology ; Animals ; Carotenoids/administration & dosage ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Cholinergic Agents/administration & dosage ; Cholinesterase Inhibitors/administration & dosage ; Cholinesterase Inhibitors/pharmacology ; Dietary Supplements ; Male ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Mitochondrial Diseases/metabolism ; Mitochondrial Diseases/pathology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study.
Autorzy :
Luo J; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Agboola F; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Grant E; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Masters CL; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Albert MS; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Johnson SC; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
McDade EM; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Vöglein J; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Fagan AM; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Benzinger T; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Massoumzadeh P; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Hassenstab J; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Bateman RJ; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Morris JC; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Perrin RJ; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Chhatwal J; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Jucker M; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Ghetti B; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Cruchaga C; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Graff-Radford NR; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Schofield PR; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Mori H; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan.
Xiong C; From the Division of Public Health Sciences (J.L.), Department of Surgery, Siteman Cancer Center Biostatistics Core (J.L.), Division of Biostatistics (J.L., F.A., E.G., C.X.), Knight Alzheimer Disease Research Center (F.A., E.G., A.M.F., T.B., P.M., J.H., R.J.B., J.C.M., R.J.P., C.X.), Department of Neurology (E.M.M., A.M.F., J.H., R.J.B., J.C.M., R.J.P.), Department of Radiology (T.B., P.M.), Department of Pathology (J.C.M., R.J.P.), Department of Immunology (J.C.M., R.J.P.), and Department of Psychiatry (C.C.), Washington University School of Medicine, St. Louis, MO; The Florey Institute (C.L.M.), University of Melbourne, Australia; Department of Neurology (M.S.A.), Johns Hopkins University School of Medicine, Baltimore, MD; Wisconsin Alzheimer's Institute and Alzheimer's Disease Research Center (S.C.J.), University of Wisconsin-Madison School of Medicine and Public Health; Geriatric Research Education and Clinical Center (S.C.J.), William S. Middleton Veterans Memorial Hospital, Madison, WI; German Center for Neurodegenerative Diseases (J.V.); Department of Neurology (J.V.), Ludwig-Maximilians-Universität München, Munich, Germany; Department of Neurology (J.C.), Massachusetts General Hospital, Harvard Medical School, Boston; Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen; German Center for Neurodegenerative Diseases (M.J.), Tübingen, Germany; Department of Pathology and Laboratory Medicine (B.G.), Indiana University, Indianapolis; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Neuroscience Research Australia (P.R.S.), Randwick; School of Medical Sciences (P.R.S.), University of New South Wales, Sydney, Australia; and Department of Clinical Neuroscience (H.M.), Osaka City University Medical School, Abenoku, Osaka, Japan. .
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Źródło :
Neurology [Neurology] 2020 Dec 08; Vol. 95 (23), pp. e3104-e3116. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease*/diagnostic imaging
Alzheimer Disease*/metabolism
Alzheimer Disease*/pathology
Alzheimer Disease*/physiopathology
Cerebral Cortex*/diagnostic imaging
Cerebral Cortex*/pathology
Cognitive Dysfunction*/diagnostic imaging
Cognitive Dysfunction*/metabolism
Cognitive Dysfunction*/pathology
Cognitive Dysfunction*/physiopathology
Amyloid beta-Peptides/*metabolism
tau Proteins/*cerebrospinal fluid
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Amyloid beta-Peptides/cerebrospinal fluid ; Aniline Compounds ; Biomarkers/metabolism ; Cross-Sectional Studies ; Female ; Hippocampus/diagnostic imaging ; Hippocampus/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Peptide Fragments/cerebrospinal fluid ; Positron-Emission Tomography ; Prodromal Symptoms ; Thiazoles ; Young Adult
Czasopismo naukowe
Tytuł :
PEA15 loss of function and defective cerebral development in the domestic cat.
Autorzy :
Graff EC; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, United States of America.; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.; Center for Neuroscience Initiative, Auburn University, Auburn, AL, United States of America Alabama, United States of America.
Cochran JN; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Kaelin CB; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Day K; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Gray-Edwards HL; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.; Department of Anatomy Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.
Watanabe R; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, United States of America.
Koehler JW; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, United States of America.; Center for Neuroscience Initiative, Auburn University, Auburn, AL, United States of America Alabama, United States of America.
Falgoust RA; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.
Prokop JW; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Cox NR; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, United States of America.; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.
Barsh GS; HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States of America.
Martin DR; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.; Center for Neuroscience Initiative, Auburn University, Auburn, AL, United States of America Alabama, United States of America.; Department of Anatomy Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States of America.
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Corporate Authors :
99 Lives Consortium
Źródło :
PLoS genetics [PLoS Genet] 2020 Dec 08; Vol. 16 (12), pp. e1008671. Date of Electronic Publication: 2020 Dec 08 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Loss of Function Mutation*
Apoptosis Regulatory Proteins/*genetics
Brain Diseases/*veterinary
Cat Diseases/*genetics
Cerebral Cortex/*metabolism
Phosphoproteins/*genetics
Animals ; Apoptosis Regulatory Proteins/metabolism ; Astrocytes/cytology ; Astrocytes/metabolism ; Brain Diseases/genetics ; Brain Diseases/pathology ; Cat Diseases/pathology ; Cats ; Cerebral Cortex/cytology ; Cerebral Cortex/growth & development ; Neurogenesis ; Phosphoproteins/metabolism
Czasopismo naukowe
Tytuł :
Connectivity of the Cerebello-Thalamo-Cortical Pathway in Survivors of Childhood Leukemia Treated With Chemotherapy Only.
Autorzy :
Phillips NS; Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.; Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.
Kesler SR; Now with School of Nursing, University of Texas at Austin.; Department of Neuro-oncology, University of Texas MD Anderson Cancer Center, Houston.
Scoggins MA; Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee.
Glass JO; Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee.
Cheung YT; School of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Liu W; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
Banerjee P; Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Ogg RJ; Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee.
Srivastava D; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
Pui CH; Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.
Robison LL; Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.
Reddick WE; Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee.
Hudson MM; Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.; Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.
Krull KR; Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.; Department of Psychology, St Jude Children's Research Hospital, Memphis, Tennessee.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Nov 02; Vol. 3 (11), pp. e2025839. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer Survivors*
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Cerebellum/*diagnostic imaging
Cerebral Cortex/*diagnostic imaging
Chemotherapy-Related Cognitive Impairment/*diagnostic imaging
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Thalamus/*diagnostic imaging
Administration, Oral ; Adolescent ; Adult ; Case-Control Studies ; Cerebellum/pathology ; Cerebellum/physiopathology ; Cerebral Cortex/pathology ; Cerebral Cortex/physiopathology ; Chemotherapy-Related Cognitive Impairment/physiopathology ; Child ; Dexamethasone/administration & dosage ; Executive Function/physiology ; Female ; Functional Neuroimaging ; Glucocorticoids/administration & dosage ; Humans ; Magnetic Resonance Imaging ; Male ; Mental Status and Dementia Tests ; Methotrexate/administration & dosage ; Neural Pathways/diagnostic imaging ; Neural Pathways/physiopathology ; Neuropsychological Tests ; Organ Size ; Parietal Lobe/diagnostic imaging ; Parietal Lobe/pathology ; Parietal Lobe/physiopathology ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/pathology ; Prefrontal Cortex/physiopathology ; Sex Factors ; Thalamus/pathology ; Thalamus/physiopathology ; Young Adult
Czasopismo naukowe
Tytuł :
Training the anxious brain: using fMRI-based neurofeedback to change brain activity in adolescence.
Autorzy :
Lipp A; School of Psychology, University of Surrey, Guildford, UK.
Cohen Kadosh K; School of Psychology, University of Surrey, Guildford, UK.
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Źródło :
Developmental medicine and child neurology [Dev Med Child Neurol] 2020 Nov; Vol. 62 (11), pp. 1239-1244. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Functional Neuroimaging*
Magnetic Resonance Imaging*
Adolescent Development/*physiology
Cerebral Cortex/*physiology
Emotional Regulation/*physiology
Nerve Net/*physiology
Neurofeedback/*methods
Neuronal Plasticity/*physiology
Phobia, Social/*physiopathology
Adolescent ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/growth & development ; Humans ; Nerve Net/diagnostic imaging ; Phobia, Social/therapy
Czasopismo naukowe
Tytuł :
Ensemble of ROI-based convolutional neural network classifiers for staging the Alzheimer disease spectrum from magnetic resonance imaging.
Autorzy :
Ahmed S; Department of Computer Engineering, Chosun University, Gwangju, South Korea.
Kim BC; Gwangju Alzheimer's disease and Related Dementias Cohort Research Center, Chosun University, Gwangju, Korea.; Department of Neurology, Chonnam National University Medical School, Gwangju, South Korea.
Lee KH; Gwangju Alzheimer's disease and Related Dementias Cohort Research Center, Chosun University, Gwangju, Korea.; Department of Biomedical Science, Chosun University, Gwangju, South Korea.; Korea Brain Research Institute, Daegu, Korea.
Jung HY; Department of Computer Engineering, Chosun University, Gwangju, South Korea.
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Corporate Authors :
Alzheimer’s Disease Neuroimaging Initiative
Źródło :
PloS one [PLoS One] 2020 Dec 08; Vol. 15 (12), pp. e0242712. Date of Electronic Publication: 2020 Dec 08 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*diagnostic imaging
Amygdala/*diagnostic imaging
Cerebral Cortex/*diagnostic imaging
Cognitive Dysfunction/*diagnostic imaging
Dementia/*diagnostic imaging
Hippocampus/*diagnostic imaging
Nerve Net/*diagnostic imaging
Aged ; Aged, 80 and over ; Alzheimer Disease/pathology ; Amygdala/pathology ; Cerebral Cortex/pathology ; Cognitive Dysfunction/pathology ; Databases, Factual ; Datasets as Topic ; Dementia/pathology ; Diagnosis, Computer-Assisted/methods ; Female ; Hippocampus/pathology ; Humans ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/statistics & numerical data ; Male ; Middle Aged ; Nerve Net/pathology ; Neuroimaging/methods ; Neuroimaging/statistics & numerical data
Czasopismo naukowe
Tytuł :
EphA7 isoforms differentially regulate cortical dendrite development.
Autorzy :
Leonard CE; Department of Biology, Georgetown University, Washington, DC, United States of America.; Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC, United States of America.
Baydyuk M; Department of Biology, Georgetown University, Washington, DC, United States of America.
Stepler MA; Department of Biology, Georgetown University, Washington, DC, United States of America.
Burton DA; Department of Biology, Georgetown University, Washington, DC, United States of America.
Donoghue MJ; Department of Biology, Georgetown University, Washington, DC, United States of America.; Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Dec 04; Vol. 15 (12), pp. e0231561. Date of Electronic Publication: 2020 Dec 04 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Cortex/*embryology
Dendrites/*metabolism
Receptor, EphA7/*metabolism
Animals ; Axons/metabolism ; Cells, Cultured ; Cerebral Cortex/metabolism ; Dendritic Spines/metabolism ; Male ; Mice, Inbred C57BL/embryology ; Neurons/metabolism ; Organogenesis ; Protein Isoforms/physiology ; Rats ; Rats, Sprague-Dawley/embryology ; Receptor, EphA7/physiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Altered habenula resting state functional connectivity in deprived veteran tobacco smokers: A pilot study.
Autorzy :
Jennings C; Rice University, Houston, Texas.
Gosnell S; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, and the Michael E. DeBakey VA Medical Center, Houston, Texas.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas.
Curtis KN; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, and the Michael E. DeBakey VA Medical Center, Houston, Texas.
Kosten T; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, and the Michael E. DeBakey VA Medical Center, Houston, Texas.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas.
Salas R; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, and the Michael E. DeBakey VA Medical Center, Houston, Texas.; Department of Neuroscience, Baylor College of Medicine, Houston, Texas.
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Źródło :
Bulletin of the Menninger Clinic [Bull Menninger Clin] 2020 Winter; Vol. 84 (1), pp. 21-34. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Connectome*/methods
Cerebral Cortex/*physiopathology
Habenula/*physiopathology
Smoking/*physiopathology
Substance Withdrawal Syndrome/*physiopathology
Tobacco Use Disorder/*physiopathology
Adult ; Cerebral Cortex/diagnostic imaging ; Female ; Habenula/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Pilot Projects ; Substance Withdrawal Syndrome/diagnostic imaging ; Tobacco Use Disorder/diagnostic imaging ; Veterans
Czasopismo naukowe
Tytuł :
Gray matter atrophy patterns within the cerebellum-neostriatum-cortical network in SCA3.
Autorzy :
Guo J; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Chen H; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Biswal BB; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Guo X; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Zhang H; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Dai L; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Zhang Y; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Li L; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Fan Y; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Han S; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Liu J; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Feng L; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark.
Wang Q; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Wang J; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Liu C; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
Chen H; From The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation (J.G., B.B.B., X.G., H.Z., L.L., Y.F., S.H., Huafu Chen), School of Medicine (J.G.), and School of Life Science and Technology, Center for Information in Medicine (X.G., H.Z., L.L., Y.F., S.H.), University of Electronic Science and Technology of China, Chengdu; Departments of Radiology (Hui Chen, Y.Z., J.L, J.W., C.L., Huafu Chen) and Laboratory Medicine (L.F.), Southwest Hospital, Department of Medical Genetics, College of Basic Medical Science (L.D.), and Department of Biomedical Engineering & Imaging Medicine (Q.W.), Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and Department of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark. .
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Źródło :
Neurology [Neurology] 2020 Dec 01; Vol. 95 (22), pp. e3036-e3044. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebellum/*pathology
Cerebral Cortex/*pathology
Gray Matter/*pathology
Machado-Joseph Disease/*pathology
Neostriatum/*pathology
Nerve Net/*pathology
Neuroimaging/*methods
Aged ; Atrophy/pathology ; Cerebellum/diagnostic imaging ; Cerebral Cortex/diagnostic imaging ; Disease Progression ; Female ; Gray Matter/diagnostic imaging ; Humans ; Machado-Joseph Disease/diagnostic imaging ; Machado-Joseph Disease/physiopathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neostriatum/diagnostic imaging ; Nerve Net/diagnostic imaging ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Central nervous system involvement in Erdheim-Chester disease: An observational cohort study.
Autorzy :
Cohen Aubart F; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Idbaih A; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Galanaud D; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Law-Ye B; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Emile JF; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Charlotte F; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Donadieu J; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Maksud P; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Seilhean D; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Amoura Z; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Hoang-Xuan K; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.
Haroche J; From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France. .
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Źródło :
Neurology [Neurology] 2020 Nov 17; Vol. 95 (20), pp. e2746-e2754. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Brain Stem/*pathology
Cerebral Cortex/*pathology
Erdheim-Chester Disease/*drug therapy
Erdheim-Chester Disease/*pathology
Protein Kinase Inhibitors/*pharmacology
Spinal Cord/*pathology
Adult ; Age Factors ; Aged ; Atrophy/pathology ; Brain Stem/diagnostic imaging ; Cerebellum/diagnostic imaging ; Cerebellum/pathology ; Cerebral Cortex/diagnostic imaging ; Diabetes Insipidus/etiology ; Erdheim-Chester Disease/complications ; Erdheim-Chester Disease/genetics ; Female ; France ; Humans ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Prognosis ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; Proto-Oncogene Proteins B-raf/genetics ; Retrospective Studies ; Spinal Cord/diagnostic imaging ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.
Autorzy :
Turrero García M; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Baizabal JM; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Tran DN; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Peixoto R; Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Wang W; Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Xie Y; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Adam MA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
English LA; Summer Honors Undergraduate Research Program, Harvard Medical School, Boston, MA 02115, USA.
Reid CM; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Brito SI; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Tolstorukov MY; Summer Honors Undergraduate Research Program, Harvard Medical School, Boston, MA 02115, USA.
Harwell CC; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA .
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Źródło :
Development (Cambridge, England) [Development] 2020 Nov 16; Vol. 147 (22). Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Cortex/*metabolism
DNA-Binding Proteins/*metabolism
GABAergic Neurons/*metabolism
Interneurons/*metabolism
Neural Stem Cells/*metabolism
Transcription Factors/*metabolism
Animals ; Cerebral Cortex/cytology ; DNA-Binding Proteins/genetics ; GABAergic Neurons/cytology ; Interneurons/cytology ; Mice ; Neural Stem Cells/cytology ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Differential functional connectivity underlying asymmetric reward-related activity in human and nonhuman primates.
Autorzy :
Lopez-Persem A; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom; .; Frontal Function and Pathology team, Institut du Cerveau, Sorbonne Université, INSERM U 1127, CNRS UMR 7225, 75013 Paris, France.
Roumazeilles L; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom.
Folloni D; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom.
Marche K; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom.
Fouragnan EF; School of Psychology, University of Plymouth, Plymouth PL4 8AA, United Kingdom.
Khalighinejad N; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom.
Rushworth MFS; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom.
Sallet J; Wellcome Integrative Neuroimaging Centre, Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, United Kingdom; .; Stem Cell and Brain Research Institute, INSERM U 1208, Université Lyon 1, 69500 Bron, France.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 28452-28462. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Reward*
Cerebral Cortex/*physiopathology
Prefrontal Cortex/*physiopathology
Animals ; Behavior ; Brain/diagnostic imaging ; Brain/physiology ; Brain Mapping ; Cerebral Cortex/diagnostic imaging ; Female ; Functional Neuroimaging/methods ; Humans ; Image Processing, Computer-Assisted ; Macaca mulatta ; Magnetic Resonance Imaging/methods ; Male ; Prefrontal Cortex/diagnostic imaging
Czasopismo naukowe
Tytuł :
Intracellular neuronal recording in awake nonhuman primates.
Autorzy :
Gao L; Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .; Department of Neurology of the Second Affiliated Hospital, Interdisciplinary Institute of Neuroscience and Technology, Zhejiang University School of Medicine, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou, China. .
Wang X; Laboratory of Auditory Neurophysiology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .
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Źródło :
Nature protocols [Nat Protoc] 2020 Nov; Vol. 15 (11), pp. 3615-3631. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Callithrix/*physiology
Cerebral Cortex/*physiology
Electrophysiology/*instrumentation
Neurons/*physiology
Animals ; Cerebral Cortex/cytology ; Electrodes, Implanted ; Electrophysiology/methods ; Equipment Design ; Neurons/cytology ; Wakefulness
Czasopismo naukowe
Tytuł :
Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Autorzy :
Song E; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Zhang C; Department of Genetics, Yale School of Medicine, New Haven, CT.; Department of Neuroscience, Yale School of Medicine, New Haven, CT.
Israelow B; Department of Immunobiology, Yale School of Medicine, New Haven, CT.; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT.
Lu-Culligan A; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Prado AV; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.
Skriabine S; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.
Lu P; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Weizman OE; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Liu F; Department of Immunobiology, Yale School of Medicine, New Haven, CT.; Department of Biomedical Engineering, Yale University, New Haven, CT.
Dai Y; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Szigeti-Buck K; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT.
Yasumoto Y; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT.
Wang G; Yale Center for Genome Analysis, West Haven, CT.
Castaldi C; Yale Center for Genome Analysis, West Haven, CT.
Heltke J; Yale Center for Genome Analysis, West Haven, CT.
Ng E; Yale Center for Genome Analysis, West Haven, CT.
Wheeler J; Yale Center for Genome Analysis, West Haven, CT.
Alfajaro MM; Department of Immunobiology, Yale School of Medicine, New Haven, CT.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
Levavasseur E; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.
Fontes B; Yale Environmental Health and Safety, Yale University, New Haven, CT.
Ravindra NG; Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.; Department of Computer Science, Yale University, New Haven, CT.
Van Dijk D; Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.; Department of Computer Science, Yale University, New Haven, CT.
Mane S; Department of Genetics, Yale School of Medicine, New Haven, CT.; Yale Center for Genome Analysis, West Haven, CT.
Gunel M; Department of Genetics, Yale School of Medicine, New Haven, CT.; Department of Neuroscience, Yale School of Medicine, New Haven, CT.; Department of Neurosurgery, Yale School of Medicine, New Haven, CT.
Ring A; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
Kazmi SAJ; Department of Laboratory Medicine, Geisinger Medical Center, Danville, PA.
Zhang K; Department of Laboratory Medicine, Geisinger Medical Center, Danville, PA.
Wilen CB; Department of Immunobiology, Yale School of Medicine, New Haven, CT.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
Horvath TL; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT.
Plu I; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Département de Neuropathologie, Paris, France.
Haik S; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Yale Environmental Health and Safety, Yale University, New Haven, CT.; Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Département de Neuropathologie, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Cellule nationale de référence des maladies de Creutzfeldt-Jakob, Paris, France.
Thomas JL; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Department of Neurology, Yale School of Medicine, New Haven, CT.
Louvi A; Department of Neuroscience, Yale School of Medicine, New Haven, CT.; Department of Neurosurgery, Yale School of Medicine, New Haven, CT.
Farhadian SF; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT.; Department of Neurology, Yale School of Medicine, New Haven, CT.
Huttner A; Department of Pathology, Yale School of Medicine, New Haven, CT.
Seilhean D; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Département de Neuropathologie, Paris, France.
Renier N; Sorbonne Université, INSERM U1127, French National Centre for Scientific Research, Joint Research Unit 7225, Paris Brain Institute, Institut du Cerveau et de la Moelle Épinière, Paris, France.
Bilguvar K; Department of Genetics, Yale School of Medicine, New Haven, CT.; Yale Center for Genome Analysis, West Haven, CT.
Iwasaki A; Department of Immunobiology, Yale School of Medicine, New Haven, CT.; Department of Molecular, Cellular, and Developmental Biology, Yale School of Medicine, New Haven, CT.; Howard Hughes Medical Institute, Chevy Chase, MD.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2021 Mar 01; Vol. 218 (3).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin-Converting Enzyme 2*/antagonists & inhibitors
Angiotensin-Converting Enzyme 2*/metabolism
COVID-19*/metabolism
COVID-19*/pathology
Cerebral Cortex*/metabolism
Cerebral Cortex*/pathology
Cerebral Cortex*/virology
Neurons*/metabolism
Neurons*/pathology
Neurons*/virology
Antibodies, Blocking/*chemistry
SARS-CoV-2/*metabolism
Animals ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Middle Aged ; Organoids/metabolism ; Organoids/pathology ; Organoids/virology
Czasopismo naukowe
Tytuł :
Reconstructing lost BOLD signal in individual participants using deep machine learning.
Autorzy :
Yan Y; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Dahmani L; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Department of Radiology, Zhengzhou University People Hospital & Henan Provincial People's Hospital, Zhengzhou, China.
Ren J; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Shen L; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Peng X; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Wang R; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
He C; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Jiang C; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Gong C; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Tian Y; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
Zhang J; Department of Neurosurgery, Tiantan Hospital, Capital Medical University, Beijing, China.
Guo Y; Department of Neurosurgery, Peking Union Medical College Hospital, Beijing, China.
Lin Y; Department of Neurosurgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Li S; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Wang M; Department of Radiology, Zhengzhou University People Hospital & Henan Provincial People's Hospital, Zhengzhou, China. .
Li L; National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China. .; Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China. .
Hong B; Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. .
Liu H; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. .; Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China. .; Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 07; Vol. 11 (1), pp. 5046. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Learning*
Brain Mapping/*methods
Cerebral Cortex/*diagnostic imaging
Image Processing, Computer-Assisted/*methods
Magnetic Resonance Imaging/*methods
Adolescent ; Adult ; Cerebral Cortex/blood supply ; Cerebral Cortex/physiology ; Datasets as Topic ; Deep Brain Stimulation ; Female ; Healthy Volunteers ; Humans ; Male ; Models, Neurological ; Oxygen/blood ; Parkinson Disease/diagnosis ; Parkinson Disease/physiopathology ; Parkinson Disease/therapy ; Young Adult
Czasopismo naukowe
Tytuł :
Localization and Expression of Sirtuins 1, 2, 6 and Plasticity-Related Proteins in the Recovery Period after a Photothrombotic Stroke in Mice.
Autorzy :
Demyanenko S; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, pr. Stachki 194/1, Rostov-on-Don 344090, Russia. Electronic address: .
Gantsgorn E; Department of Pharmacology and Clinical Pharmacology, Rostov State Medical University, st. Nakhichevansky 29, Rostov-on-Don 344022, Russia.
Rodkin S; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, pr. Stachki 194/1, Rostov-on-Don 344090, Russia.
Sharifulina S; Neuroscience Center, HiLife, University of Helsinki, Haartmaninkatu 8, P.O. Box 63, FI-00014 Helsinki, Finland.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105152. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Neuronal Plasticity*
Astrocytes/*enzymology
Cerebral Cortex/*enzymology
Intracranial Thrombosis/*complications
Neurons/*enzymology
Sirtuin 1/*metabolism
Sirtuin 2/*metabolism
Sirtuins/*metabolism
Stroke/*enzymology
Animals ; Apoptosis ; Astrocytes/pathology ; Cerebral Cortex/pathology ; Cerebral Cortex/physiopathology ; Disease Models, Animal ; Male ; Mice ; Neurons/pathology ; Recovery of Function ; Signal Transduction ; Stroke/etiology ; Stroke/pathology ; Stroke/physiopathology ; Time Factors
Czasopismo naukowe
Tytuł :
Deep posteromedial cortical rhythm in dissociation.
Autorzy :
Vesuna S; Department of Bioengineering, Stanford University, Stanford, CA, USA.
Kauvar IV; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
Richman E; Department of Bioengineering, Stanford University, Stanford, CA, USA.
Gore F; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Oskotsky T; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, Stanford University, Stanford, CA, USA.
Sava-Segal C; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Luo L; Department of Biology, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Malenka RC; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Henderson JM; Department of Neurosurgery, Stanford University, Stanford, CA, USA.
Nuyujukian P; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Electrical Engineering, Stanford University, Stanford, CA, USA.; Department of Neurosurgery, Stanford University, Stanford, CA, USA.
Parvizi J; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA, USA. .; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. .; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. .
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Źródło :
Nature [Nature] 2020 Oct; Vol. 586 (7827), pp. 87-94. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Brain Waves/*physiology
Cerebral Cortex/*physiology
Dissociative Disorders/*physiopathology
Action Potentials/drug effects ; Animals ; Behavior/drug effects ; Brain Waves/drug effects ; Cerebral Cortex/cytology ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/drug effects ; Dissociative Disorders/diagnostic imaging ; Electrophysiology ; Female ; Humans ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/metabolism ; Ketamine/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/drug effects ; Optogenetics ; Self Report ; Thalamus/cytology ; Thalamus/diagnostic imaging ; Thalamus/drug effects ; Thalamus/physiology
Czasopismo naukowe
Tytuł :
Lysophosphatidic acid increased infarct size in the early stage of cerebral ischemia-reperfusion with increased BBB permeability.
Autorzy :
Chi OZ; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA. Electronic address: .
Mellender SJ; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Kiss GK; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Chiricolo A; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Liu X; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Patel N; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
Jacinto E; Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
Weiss HR; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105029. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Reperfusion*
Blood-Brain Barrier/*drug effects
Capillary Permeability/*drug effects
Cerebral Cortex/*drug effects
Infarction, Middle Cerebral Artery/*therapy
Lysophospholipids/*toxicity
Reperfusion Injury/*chemically induced
Animals ; Blood-Brain Barrier/physiopathology ; Cerebral Cortex/enzymology ; Cerebral Cortex/pathology ; Disease Models, Animal ; Infarction, Middle Cerebral Artery/enzymology ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/physiopathology ; Male ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Inbred F344 ; Reperfusion Injury/enzymology ; Reperfusion Injury/pathology ; Reperfusion Injury/physiopathology ; Ribosomal Protein S6 Kinases/metabolism
Czasopismo naukowe
Tytuł :
Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex.
Autorzy :
Laukoter S; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Pauler FM; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Beattie R; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Amberg N; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Hansen AH; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Streicher C; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Penz T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.
Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.
Hippenmeyer S; Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Sep 23; Vol. 107 (6), pp. 1160-1179.e9. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genomic Imprinting*
Transcriptome*
Uniparental Disomy*
Cerebral Cortex/*metabolism
Animals ; Astrocytes/classification ; Astrocytes/metabolism ; Cerebral Cortex/cytology ; Female ; Male ; Mice ; Mice, Inbred C57BL ; RNA-Seq ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Multiple timescales of neural dynamics and integration of task-relevant signals across cortex.
Autorzy :
Spitmaan M; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755.
Seo H; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06511.
Lee D; The Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD 21218.; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21218.; Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218.
Soltani A; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 08; Vol. 117 (36), pp. 22522-22531. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cerebral Cortex*/cytology
Cerebral Cortex*/physiology
Nerve Net/*physiology
Neurons/*physiology
Animals ; Choice Behavior/physiology ; Female ; Macaca ; Male ; Nerve Net/cytology ; Reinforcement, Psychology ; Reward
Czasopismo naukowe

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