Temat: "Cevanes" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2.
Autorzy:: Wang WJ; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.
Chen Y; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; Gradaute Institute of New Drug Development, China Medical University, Taichung, Taiwan.; New Drug Development Center, China Medical University, Taichung, Taiwan.
Su WC; International Master's Program of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Research Center for Emerging Viruses, China Medical University Hospital, Taichung, Taiwan.
Liu YY; Department of Public Health, China Medical University, Taichung, Taiwan.
Shen WJ; College of Medicine, Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Chang WC; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.
Huang ST; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Chinese Medicine, Research Cancer Center for Traditional Chinese Medicine, China Medical University Hospital, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; An-Nan Hospital, China Medical University, Tainan, Taiwan.
Lin CW; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.
Wang YC; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; Gradaute Institute of New Drug Development, China Medical University, Taichung, Taiwan.; New Drug Development Center, China Medical University, Taichung, Taiwan.
Yang CS; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; Gradaute Institute of New Drug Development, China Medical University, Taichung, Taiwan.; New Drug Development Center, China Medical University, Taichung, Taiwan.
Hou MH; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; Gradaute Institute of New Drug Development, China Medical University, Taichung, Taiwan.; New Drug Development Center, China Medical University, Taichung, Taiwan.
Chou YC; RNA Technology Platform and Gene Manipulation Core, Biomedical Translation Research Center (BioTReC), Academia Sinica, Taipei, Taiwan.
Wu YC; Chinese Medicine Research and Development Center, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan.
Wang SC; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; College of Medicine, Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.; Cancer Biology and Drug Discovery Ph.D. Program, China Medical University, Taichung, Taiwan.; Department of Biotechnology, Asia University, Taichung, Taiwan.
Hung MC; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan.; College of Medicine, Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.; Department of Biotechnology, Asia University, Taichung, Taiwan.; Pokaż więcej
Źródło:: Journal of food biochemistry [J Food Biochem] 2022 Oct; Vol. 46 (10), pp. e14354. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cevanes*
COVID-19 Drug Treatment*
Angiotensin-Converting Enzyme 2/genetics ; Binding Sites ; COVID-19 Vaccines ; Glycoproteins ; Humans ; Molecular Docking Simulation ; Peptidyl-Dipeptidase A/chemistry ; Protein Binding ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Viral Proteins/metabolism ; Virus Internalization
SCR Organism:: SARS-CoV-2 variants

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Skocz do pozycji: 2.

Tytuł:: An integrated strategy to reveal the potential anti-asthma mechanism of peimine by metabolite profiling, network pharmacology, and molecular docking.
Autorzy:: Tian X; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei, Medical University, Shijiazhuang, P. R. China.
Wei J; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei, Medical University, Shijiazhuang, P. R. China.
Yang M; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei, Medical University, Shijiazhuang, P. R. China.
Niu Y; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei, Medical University, Shijiazhuang, P. R. China.
Liu M; Chemical Engineering Institute, Shijiazhuang University, Shijiazhuang, P. R. China.
Du Y; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei, Medical University, Shijiazhuang, P. R. China.
Jin Y; Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, P. R. China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2022 Aug; Vol. 45 (15), pp. 2819-2832. Date of Electronic Publication: 2022 Jun 05.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Asthmatic Agents*/pharmacology
Cevanes*
Drugs, Chinese Herbal*/chemistry
Drugs, Chinese Herbal*/pharmacology
Molecular Docking Simulation ; Network Pharmacology

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Skocz do pozycji: 3.

Tytuł:: Pharmacokinetic interaction between peimine and paeoniflorin in rats and its potential mechanism.
Autorzy:: Chen Q; Department of Thyroid and Breast Surgery, Weifang Yidu Central Hospital, Weifang, Shandong, 262500, China.
Yin C; Department of Pediatrics, Weifang Yidu Central Hospital, Weifang, China.
Li Y; Department of Pediatrics, Weifang Yidu Central Hospital, Weifang, China.
Yang Z; Qingzhou Medical Security Bureau, Weifang, China.
Tian Z; Department of Human Anatomy, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 129-133.
Typ publikacji:: Journal Article
MeSH Terms:: Cevanes/*pharmacology
Glucosides/*pharmacokinetics
Microsomes, Liver/*metabolism
Monoterpenes/*pharmacokinetics
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Animals ; Area Under Curve ; Caco-2 Cells ; Cevanes/administration & dosage ; Cytochrome P-450 CYP3A/metabolism ; Drug Interactions ; Glucosides/administration & dosage ; Half-Life ; Humans ; Male ; Monoterpenes/administration & dosage ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 4.

Tytuł:: Interaction of a Novel Alternatively Spliced Variant of HSD11B1L with Parkin Enhances the Carcinogenesis Potential of Glioblastoma: Peiminine Interferes with This Interaction.
Autorzy:: Fu RH; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Hong SY; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Department of Medicine, School of Medicine, China Medical University, Taichung 40447, Taiwan.; Division of Pediatric Neurology, China Medical University Children's Hospital, Taichung 40447, Taiwan.
Tsai CW; Department of Nutrition, China Medical University, Taichung 40402, Taiwan.
Liu SP; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Chiu SC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Wu MZ; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Shyu WC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Lin SZ; Buddhist Tzu Chi Bioinnovation Center, Tzu Chi Foundation, Hualien 97002, Taiwan.; Department of Neurosurgery, Buddhist Tzu Chi General Hospital, Hualien 97002, Taiwan.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Mar 14; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 11-beta-Hydroxysteroid Dehydrogenase Type 1*/drug effects
11-beta-Hydroxysteroid Dehydrogenase Type 1*/genetics
11-beta-Hydroxysteroid Dehydrogenase Type 1*/metabolism
Brain Neoplasms*/drug therapy
Brain Neoplasms*/genetics
Brain Neoplasms*/metabolism
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioblastoma*/metabolism
Ubiquitin-Protein Ligases*/drug effects
Ubiquitin-Protein Ligases*/genetics
Ubiquitin-Protein Ligases*/metabolism
Animals ; Humans ; Mice ; Carcinogenesis/genetics ; Cevanes/pharmacology ; Protein Isoforms/drug effects ; Protein Isoforms/genetics ; Protein Isoforms/metabolism

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Skocz do pozycji: 5.

Tytuł:: Identification of the Molecular Mechanisms of Peimine in the Treatment of Cough Using Computational Target Fishing.
Autorzy:: Zhang L; Department of Food Science, Zhejiang Pharmaceutical College, Ningbo 315000, China.
Cui M; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, Ningbo 315000, China.
Chen S; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, Ningbo 315000, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Mar 02; Vol. 25 (5). Date of Electronic Publication: 2020 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: Computational Biology*
Cough*/drug therapy
Cough*/genetics
Cough*/metabolism
Gene Expression Profiling*
Models, Biological*
Cevanes/*therapeutic use
Protein Interaction Maps/*drug effects
Signal Transduction/*drug effects
Cevanes/chemistry ; Drugs, Chinese Herbal ; Humans ; Medicine, Chinese Traditional

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Skocz do pozycji: 6.

Tytuł:: Peiminine Protects against Lipopolysaccharide-Induced Mastitis by Inhibiting the AKT/NF-κB, ERK1/2 and p38 Signaling Pathways.
Autorzy:: Gong Q; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Li Y; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Ma H; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Guo W; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Kan X; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Xu D; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Liu J; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .
Fu S; College of Veterinary Medicine, Jilin University, Changchun 130062, China. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Sep 06; Vol. 19 (9). Date of Electronic Publication: 2018 Sep 06.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*administration & dosage
Cevanes/*administration & dosage
Lipopolysaccharides/*adverse effects
Mastitis/*drug therapy
NF-kappa B/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Cells, Cultured ; Cevanes/pharmacology ; Disease Models, Animal ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Female ; Gene Expression Regulation/drug effects ; Infusions, Parenteral ; MAP Kinase Signaling System/drug effects ; Mammary Glands, Animal/cytology ; Mammary Glands, Animal/drug effects ; Mammary Glands, Animal/metabolism ; Mastitis/chemically induced ; Mastitis/metabolism ; Mice ; Phosphorylation/drug effects

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Skocz do pozycji: 7.

Tytuł:: Determination and Visualization of Peimine and Peiminine Content in Fritillaria thunbergii Bulbi Treated by Sulfur Fumigation Using Hyperspectral Imaging with Chemometrics.
Autorzy:: He J; Zhejiang Academy of Traditional Chinese Medicine, Key Laboratory of Research and Development of Chinese Medicine of Zhejiang Province, Hangzhou 310007, China. .
He Y; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. .
Zhang AC; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2017 Aug 23; Vol. 22 (9). Date of Electronic Publication: 2017 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Spectrum Analysis*/methods
Sulfur*/chemistry
Cevanes/*chemistry
Fritillaria/*chemistry
Fumigation/*methods
Cevanes/analysis ; Regression Analysis

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Skocz do pozycji: 8.

Tytuł:: Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic Receptors.
Autorzy:: Alberola-Die A; División de Fisiología, Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Apdo. 99, E-03080 Alicante, Spain.
Encinar JA; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, E-03202 Elche, Spain.
Cobo R; División de Fisiología, Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Apdo. 99, E-03080 Alicante, Spain.
Fernández-Ballester G; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, E-03202 Elche, Spain.
González-Ros JM; Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, E-03202 Elche, Spain.
Ivorra I; División de Fisiología, Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Apdo. 99, E-03080 Alicante, Spain.
Morales A; División de Fisiología, Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Apdo. 99, E-03080 Alicante, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 19; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 19.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Cevanes/*pharmacology
Gene Expression Regulation/*drug effects
Muscles/*drug effects
Oocytes/*drug effects
Plant Extracts/*pharmacology
Receptors, Nicotinic/*metabolism
Animals ; Drugs, Chinese Herbal/pharmacology ; Muscles/metabolism ; Oocytes/metabolism ; Receptors, Nicotinic/genetics ; Xenopus laevis

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Skocz do pozycji: 9.

Tytuł:: Peiminine Reduces ARTS-Mediated Degradation of XIAP by Modulating the PINK1/Parkin Pathway to Ameliorate 6-Hydroxydopamine Toxicity and α-Synuclein Accumulation in Parkinson's Disease Models In Vivo and In Vitro.
Autorzy:: Hsu YL; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Hung HS; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Tsai CW; Department of Nutrition, China Medical University, Taichung 40402, Taiwan.
Liu SP; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Chiang YT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Kuo YH; Department of Nursing, Taipei Veterans General Hospital, Taipei 12217, Taiwan.
Shyu WC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.
Lin SZ; Bioinnovation Center, Tzu Chi Foundation, Department of Neurosurgery, Buddhist Tzu Chi General Hospital, Tzu Chi University, Hualien 970, Taiwan.
Fu RH; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung 40447, Taiwan.; Department of Psychology, Asia University, Taichung 41354, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 23; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis Regulatory Proteins/*metabolism
Caenorhabditis elegans Proteins/*metabolism
Cevanes/*pharmacology
Parkinson Disease/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Ubiquitin-Protein Ligases/*metabolism
X-Linked Inhibitor of Apoptosis Protein/*metabolism
alpha-Synuclein/*metabolism
Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/metabolism ; Dopamine/metabolism ; Dopaminergic Neurons/metabolism ; Nerve Degeneration/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Substantia Nigra/metabolism ; Ubiquitin/metabolism

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Skocz do pozycji: 10.

Tytuł:: Antiallergic effects of peiminine through the regulation of inflammatory mediators in HMC-1 cells.
Autorzy:: Lee B; Department of Anatomy, College of Korean Medicine, Kyung Hee University Seoul , Republic of Korea.
Kim EY
Kim JH
Min JH
Jeong DW
Jun JY
Cho CY
Sohn Y
Jung HS; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2015; Vol. 37 (4), pp. 351-8. Date of Electronic Publication: 2015 Jun 30.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Allergic Agents/*pharmacology
Cevanes/*pharmacology
Histamine Release/*drug effects
Mast Cells/*drug effects
Animals ; Anti-Allergic Agents/administration & dosage ; Anti-Allergic Agents/chemistry ; Blotting, Western ; Cell Culture Techniques ; Cell Line ; Cell Survival/drug effects ; Cevanes/administration & dosage ; Cevanes/chemistry ; Cytokines/immunology ; Enzyme-Linked Immunosorbent Assay ; Histamine Release/immunology ; Humans ; Immunoglobulin E/immunology ; Mast Cells/immunology ; Passive Cutaneous Anaphylaxis/immunology ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction

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Skocz do pozycji: 11.

Tytuł:: Pharmacokinetics, tissue distribution and excretion of verticinone from F. hupehensis in rats.
Autorzy:: Wu X; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy of Tongji Medical College, Huazhong University of Science and Technology, 13# Hangkong Road, Wuhan 430030, China. wuxiao_.
Sun JG; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24# Tongjiaxiang, Nanjing 210009, China. jgsun_.
Peng Y; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24# Tongjiaxiang, Nanjing 210009, China. .
Liang Y; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24# Tongjiaxiang, Nanjing 210009, China. .
Wang GJ; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, 24# Tongjiaxiang, Nanjing 210009, China. .
Chen H; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy of Tongji Medical College, Huazhong University of Science and Technology, 13# Hangkong Road, Wuhan 430030, China. .
Wu JZ; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy of Tongji Medical College, Huazhong University of Science and Technology, 13# Hangkong Road, Wuhan 430030, China. .
Zhang P; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy of Tongji Medical College, Huazhong University of Science and Technology, 13# Hangkong Road, Wuhan 430030, China. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2014 Dec 10; Vol. 19 (12), pp. 20613-26. Date of Electronic Publication: 2014 Dec 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cevanes/*pharmacokinetics
Expectorants/*pharmacokinetics
Fritillaria/*chemistry
Plant Extracts/*pharmacokinetics
Animals ; Blood Proteins/chemistry ; Cevanes/administration & dosage ; Cevanes/chemistry ; Drug Evaluation, Preclinical ; Expectorants/administration & dosage ; Expectorants/chemistry ; Female ; Humans ; Male ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Rats, Sprague-Dawley ; Tissue Distribution

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Skocz do pozycji: 12.

Tytuł:: In vitro effects of peimine on the activity of cytochrome P450 enzymes.
Autorzy:: Li M; Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Liu X; Department of Pharmacy, Qilu Hospital of Shandong University, Jinan, China.
Wang Y; Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Ju X; Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 Oct; Vol. 50 (10), pp. 1202-1207. Date of Electronic Publication: 2020 May 05.
Typ publikacji:: Journal Article
MeSH Terms:: Cevanes/*pharmacology
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Cytochrome P-450 Enzyme System/metabolism ; Humans ; Liver/metabolism ; Microsomes, Liver/metabolism

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Skocz do pozycji: 13.

Tytuł:: Solid acids assisted matrix solid-phase dispersion microextraction of alkaloids by capillary electrophoresis coupled with quadrupole time-of-flight mass spectrometry.
Autorzy:: Wang QY; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Dong X; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Yang J; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Zhen XT; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Ye LH; Department of Traditional Chinese Medicine, Hangzhou Red Cross Hospital, Hangzhou, China.
Chu C; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Wang B; Lianyungang Hospital of Traditional Chinese Medicine, Lianyungang, Jiangsu, P. R. China.
Hu YH; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Zheng H; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.
Cao J; College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2019 Dec; Vol. 42 (23), pp. 3579-3588. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:: Evaluation Study; Journal Article
MeSH Terms:: Alkaloids/*analysis
Alkaloids/*isolation & purification
Drugs, Chinese Herbal/*analysis
Drugs, Chinese Herbal/*isolation & purification
Electrophoresis, Capillary/*methods
Solid Phase Microextraction/*methods
Tandem Mass Spectrometry/*methods
Cevanes/analysis ; Cevanes/isolation & purification ; Limit of Detection

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Skocz do pozycji: 14.

Tytuł:: Simultaneous Determination and Pharmacokinetics of Peimine and Peiminine in Beagle Dog Plasma by UPLC-MS/MS after the Oral Administration of Fritillariae ussuriensis Maxim and Fritillariae thunbergii Miq Powder.
Autorzy:: Wang Z; School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang, China. .
Cao F; School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang, China. .
Chen Y; School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang, China. .
Tang Z; School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang, China. .
Wang Z; School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang, China. wangzhen_.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Jun 28; Vol. 23 (7). Date of Electronic Publication: 2018 Jun 28.
Typ publikacji:: Journal Article
MeSH Terms:: Cevanes/*blood
Cevanes/*pharmacokinetics
Chromatography, Liquid/*methods
Drugs, Chinese Herbal/*chemistry
Fritillaria/*chemistry
Tandem Mass Spectrometry/*methods
Administration, Oral ; Animals ; Dogs ; Drugs, Chinese Herbal/administration & dosage ; Male

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Skocz do pozycji: 15.

Tytuł:: The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
Autorzy:: Chao X; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, P. R.China.; The College of Basic Medicine Sciences, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.
Wang G; The College of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.
Tang Y; The College of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.
Dong C; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, P. R.China.
Li H; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, P. R.China.
Wang B; The College of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.
Wu J; The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, P. R.China.
Zhao J; The College of Basic Medicine Sciences, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, P. R.China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Jan 07; Vol. 14 (1), pp. e0201864. Date of Electronic Publication: 2019 Jan 07 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Carcinoma, Hepatocellular/*metabolism
Cell Proliferation/*drug effects
Cevanes/*pharmacology
Liver Neoplasms/*metabolism
Signal Transduction/*drug effects
Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Membrane Potential, Mitochondrial/drug effects ; Neoplasm Proteins/metabolism

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Skocz do pozycji: 16.

Tytuł:: Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways.
Autorzy:: Chen G; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Liu J; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Jiang L; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Ran X; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
He D; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Li Y; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Huang B; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Wang W; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Liu D; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .
Fu S; College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Mar 12; Vol. 19 (3). Date of Electronic Publication: 2018 Mar 12.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Anti-Inflammatory Agents/*pharmacology
Cevanes/*pharmacology
Dopaminergic Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Animals ; Cell Death ; Cell Line ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Dopaminergic Neurons/metabolism ; Female ; Interleukins/genetics ; Interleukins/metabolism ; Lipopolysaccharides/toxicity ; Mice ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Wistar ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism

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Tytuł:: The Isosteroid Alkaloid Imperialine from Bulbs of Fritillaria cirrhosa Mitigates Pulmonary Functional and Structural Impairment and Suppresses Inflammatory Response in a COPD-Like Rat Model.
Autorzy:: Wang D; Department of Pharmacognosy, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, China; Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
Du Q; Department of Pharmacognosy, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, China.
Li H; Department of Pharmacognosy, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, China.
Wang S; Department of Pharmacognosy, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu 610041, China.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2016; Vol. 2016, pp. 4192483. Date of Electronic Publication: 2016 Jul 20.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids/*pharmacology
Fritillaria/*chemistry
Inflammation/*drug therapy
Lung/*drug effects
Plant Extracts/*pharmacology
Pulmonary Disease, Chronic Obstructive/*physiopathology
Animals ; Anti-Inflammatory Agents/pharmacology ; Body Weight ; Cevanes/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Immunohistochemistry ; Lung/metabolism ; Male ; Plant Roots/chemistry ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Rats ; Rats, Wistar ; Respiratory Function Tests ; Steroids/metabolism

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Skocz do pozycji: 18.

Tytuł:: Simultaneous determination of five constituents in Qinpijiegu capsule by high-performance liquid chromatography coupled with tandem mass spectrometry.
Autorzy:: Zhao M; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Ding W; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Wang S; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Gao M; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Fu S; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Zhang J; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Li T; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Wu Y; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China.
Wang Q; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang 050017, P.R. China .; Pokaż więcej
Źródło:: Journal of chromatographic science [J Chromatogr Sci] 2015 Feb; Vol. 53 (2), pp. 274-9. Date of Electronic Publication: 2014 Jun 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromatography, High Pressure Liquid/*methods
Drugs, Chinese Herbal/*analysis
Drugs, Chinese Herbal/*chemistry
Tandem Mass Spectrometry/*methods
Cevanes/analysis ; Cevanes/chemistry ; Coumarins/analysis ; Coumarins/chemistry ; Limit of Detection ; Linear Models ; Reproducibility of Results

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Skocz do pozycji: 19.

Tytuł:: In vitro and in vivo antitumor activity of Bulbus Fritillariae Cirrhosae and preliminary investigation of its mechanism.
Autorzy:: Wang DD; a Department of Pharmacognosy, West China College of Pharmacy , Sichuan University , Chengdu , PR China.
Feng Y
Li Z
Zhang L
Wang S
Zhang CY
Wang XX
Liu ZY; Pokaż więcej
Źródło:: Nutrition and cancer [Nutr Cancer] 2014; Vol. 66 (3), pp. 441-52. Date of Electronic Publication: 2014 Feb 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alkaloids/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Drugs, Chinese Herbal/*chemistry
Liliaceae/*chemistry
Alkaloids/analysis ; Animals ; Caspase 3/metabolism ; Cell Line, Tumor/drug effects ; Cevanes/analysis ; Cevanes/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Drugs, Chinese Herbal/analysis ; Humans ; Male ; Mice, Inbred ICR ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; Steroids/analysis ; Steroids/chemistry

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Skocz do pozycji: 20.

Tytuł:: Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages.
Autorzy:: Yi PF; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Jilin University , Changchun, Jilin , China .
Wu YC
Dong HB
Guo Y
Wei Q
Zhang C
Song Z
Qin QQ
Lv S
Wu SC
Fu BD; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2013 Oct; Vol. 35 (5), pp. 567-72. Date of Electronic Publication: 2013 Aug 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cevanes/*pharmacology
Cytokines/*immunology
MAP Kinase Signaling System/*drug effects
Macrophages/*immunology
Transcription Factor RelA/*immunology
Animals ; Cell Line ; Cytokines/metabolism ; Extracellular Signal-Regulated MAP Kinases/immunology ; I-kappa B Kinase/immunology ; Lipopolysaccharides/toxicity ; MAP Kinase Signaling System/immunology ; Macrophages/metabolism ; Mice

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