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Tytuł :
SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.
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Źródło :
Nature Structural & Molecular Biology. 27(5):438-449
Czasopismo naukowe
Tytuł :
A chemogenomic approach to identify personalized therapy for patients with relapse or refractory acute myeloid leukemia: results of a prospective feasibility study
Autorzy :
Collignon, A.
Hospital, M. A.
Montersino, C.
Courtier, F.
Charbonnier, A.
Saillard, C.
D’Incan, E.
Mohty, B.
Guille, A.
Adelaïde, J.
Carbuccia, N.
Garnier, S.
Mozziconacci, M. J.
Zemmour, C.
Pakradouni, J.
Restouin, A.
Castellano, R.
Chaffanet, M.
Birnbaum, D.Aff3, IDs4140802003305_cor19
Collette, Y.Aff2, IDs4140802003305_cor20
Vey, N.Aff1, IDs4140802003305_cor21
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Źródło :
Blood Cancer Journal. 10(6)
Czasopismo naukowe
Tytuł :
Author Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.Aff1, IDs415940200448y_cor22
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Źródło :
Nature Structural & Molecular Biology. 27(6):603-603
Czasopismo naukowe
Tytuł :
Publisher Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.Aff1, IDs415940200447z_cor22
Pokaż więcej
Źródło :
Nature Structural & Molecular Biology. 27(6):604-604
Czasopismo naukowe
Tytuł :
Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial.
Autorzy :
Bertucci F; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France. .; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France. .
Gonçalves A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Guille A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Adelaïde J; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Garnier S; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Carbuccia N; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Billon E; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Finetti P; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Sfumato P; Biostatistics Unit, Institut Paoli-Calmettes, Marseille, France.
Monneur A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Pécheux C; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.
Khran M; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.; Aix-Marseille University, Inserm, U1251-MMG, Marseille Medical Genetics, Marseille, France.
Brunelle S; Department of Imaging, Institut Paoli-Calmettes, Marseille, France.
Mescam L; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Thomassin-Piana J; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Poizat F; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Turrini O; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Lambaudie E; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Provansal M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Extra JM; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Madroszyk A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Gilabert M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Sabatier R; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Vicier C; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Mamessier E; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chabannon C; Biobank, Department of Hematology, Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Viens P; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
André F; Department of Medical Oncology, Gustave Roussy Cancer Campus, UMR981 Inserm, Villejuif, France.; Paris Sud University, Orsay, France.
Gravis G; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Popovici C; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chaffanet M; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
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Źródło :
Genome medicine [Genome Med] 2021 May 18; Vol. 13 (1), pp. 87. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Case Report: Two Cases of Metastatic Pancreatoblastoma in Adults: Efficacy of Folfirinox and Implication of the Wnt/β-Catenin Pathway in Genomic Analysis.
Autorzy :
Raoul JL; Department of Medical Oncology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
Oziel-Taieb S; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Lecomte T; Department of Hepatogastroenterology, CHU Tours, Tours, France.
Adelaide J; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Guille A; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Chaffanet M; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Poizat F; Department of Pathology, Institut Paoli-Calmettes, Marseille, France.
Heymann MF; Department of Pathology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
Barbier L; Department of Digestive Surgery, CHU Tours, Tours, France.
Bertucci F; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
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Źródło :
Frontiers in oncology [Front Oncol] 2021 Mar 16; Vol. 11, pp. 564506. Date of Electronic Publication: 2021 Mar 16 (Print Publication: 2021).
Typ publikacji :
Case Reports
Raport
Tytuł :
Gains of EPOR and ERG genes in adult erythroleukaemia.
Autorzy :
Adélaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Cervera N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Murati A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Mozziconacci MJ; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Vey N; Hématologie, Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France.
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Gelsi-Boyer V; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
British journal of haematology [Br J Haematol] 2020 May; Vol. 189 (4), pp. e174-e177. Date of Electronic Publication: 2020 Mar 29.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Erythroblastic, Acute/*genetics
Receptors, Erythropoietin/*genetics
Adult ; Gene Dosage ; Humans ; Prognosis ; Transcriptional Regulator ERG/genetics
Raport
Tytuł :
NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers.
Autorzy :
Bertucci F; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Rypens C; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Finetti P; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Adélaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Monneur A; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Garnier S; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Dirix P; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Gonçalves A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Vermeulen P; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Debeb BG; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Wang X; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dirix L; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Ueno NT; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Viens P; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Cristofanilli M; Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA.
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Van Laere S; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
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Źródło :
Molecular oncology [Mol Oncol] 2020 Mar; Vol. 14 (3), pp. 504-519. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
DNA Repair/*genetics
Inflammatory Breast Neoplasms/*genetics
Receptor, Notch4/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Comparative Genomic Hybridization ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 6/genetics ; DNA Copy Number Variations ; Female ; Genomics ; High-Throughput Nucleotide Sequencing ; Humans ; Inflammatory Breast Neoplasms/mortality ; Inflammatory Breast Neoplasms/pathology ; Middle Aged ; Mutation ; Neoplasm Staging ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
Author Correction: Genomic characterization of metastatic breast cancers.
Autorzy :
Bertucci F; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France. .
Ng CKY; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Patsouris A; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Droin N; Genomic Core Facility UMS AMMICA Gustave Roussy Cancer Campus, Villejuif, France.; INSERM, US23, Villejuif, France.; CNRS, UMS3665, Villejuif, France.
Piscuoglio S; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.
Carbuccia N; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Soria JC; Université Paris Sud, Orsay, France.; Drug Development Department (DITEP), Gustave Roussy Cancer Campus, Villejuif, France.
Dien AT; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Adnani Y; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Kamal M; Department of Translational Research, Institut Curie, Saint-Cloud, France.
Garnier S; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Meurice G; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Jimenez M; Unicancer, Paris, France.
Dogan S; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Verret B; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Chaffanet M; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Bachelot T; Centre Léon Bérard, Lyon, France.
Campone M; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Lefeuvre C; Centre Eugène Marquis, Rennes, France.
Bonnefoi H; Institut Bergonié, Bordeaux, France.
Dalenc F; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Jacquet A; Unicancer, Paris, France.
De Filippo MR; Institute of Pathology, University Hospital Basel, Basel, Switzerland.
Babbar N; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Birnbaum D; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Filleron T; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Le Tourneau C; Department of Drug Development and Innovation, Institut Curie, Saint-Cloud, France.; INSERM U900, Saint-Cloud, France.; Versailles Saint Quentin en Yvelines University, Montigny le Bretonneux, France.
André F; Université Paris Sud, Orsay, France. .; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France. .; Department of Medical Oncology, Gustave Roussy, Villejuif, France. .
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Źródło :
Nature [Nature] 2019 Aug; Vol. 572 (7767), pp. E7.
Typ publikacji :
Published Erratum
Tytuł :
Targeted molecular characterization shows differences between primary and secondary myelofibrosis.
Autorzy :
Courtier F; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Garnier S; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Carbuccia N; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Guille A; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Adélaide J; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Chaffanet M; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Hirsch P; Centre de Recherche Saint-Antoine CRSA, APHP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, Paris, France.
Paz DL; Laboratoire d'Hématologie, CHU d'Angers, Angers, France.
Slama B; Centre Hospitalier Général d'Avignon, Service d'Onco-Hématologie, France.
Vey N; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Aix-Marseille Université, Marseille, France.; Département d'Hématologie, IPC, Marseille, France.
Ugo V; Laboratoire d'Hématologie, CHU d'Angers, Angers, France.
Delhommeau F; Centre de Recherche Saint-Antoine CRSA, APHP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, Paris, France.
Rey J; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Hématologie, IPC, Marseille, France.
Birnbaum D; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Murati A; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Département de BioPathologie, IPC, Marseille, France.
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Źródło :
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2019 Jul 24. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases.
Autorzy :
Tyran M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département de Radiothérapie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Carbuccia N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Garnier S; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Adelaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Finetti P; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Toulzian J; Département d'Anatomopathologie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Viens P; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
Tallet A; Département de Radiothérapie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Goncalves A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
Metellus P; Département de Neurochirurgie et de Neuro-oncologie, Hôpital Privé Clairval, Ramsay-Générale de Santé and Institut de Neurophysiopathologie Equipe 10, UMR0751, CNRS, 13009 Marseille, France. .
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Bertucci F; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
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Źródło :
Cancers [Cancers (Basel)] 2019 May 13; Vol. 11 (5). Date of Electronic Publication: 2019 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genomic characterization of metastatic breast cancers.
Autorzy :
Bertucci F; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Ng CKY; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Patsouris A; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Droin N; Genomic Core Facility UMS AMMICA Gustave Roussy Cancer Campus, Villejuif, France.; INSERM, US23, Villejuif, France.; CNRS, UMS3665, Villejuif, France.
Piscuoglio S; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.
Carbuccia N; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Soria JC; Université Paris Sud, Orsay, France.; Drug Development Department (DITEP), Gustave Roussy Cancer Campus, Villejuif, France.
Dien AT; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Adnani Y; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Kamal M; Department of Translational Research, Institut Curie, Saint-Cloud, France.
Garnier S; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Meurice G; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Jimenez M; Unicancer, Paris, France.
Dogan S; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Verret B; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Chaffanet M; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Bachelot T; Centre Léon Bérard, Lyon, France.
Campone M; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Lefeuvre C; Centre Eugène Marquis, Rennes, France.
Bonnefoi H; Institut Bergonié, Bordeaux, France.
Dalenc F; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Jacquet A; Unicancer, Paris, France.
De Filippo MR; Institute of Pathology, University Hospital Basel, Basel, Switzerland.
Babbar N; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Birnbaum D; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Filleron T; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Le Tourneau C; Department of Drug Development and Innovation, Institut Curie, Saint-Cloud, France.; INSERM U900, Saint-Cloud, France.; Versailles Saint Quentin en Yvelines University, Montigny le Bretonneux, France.
André F; Université Paris Sud, Orsay, France. .; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France. .; Department of Medical Oncology, Gustave Roussy, Villejuif, France. .
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Źródło :
Nature [Nature] 2019 May; Vol. 569 (7757), pp. 560-564. Date of Electronic Publication: 2019 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Genomics*
Mutation*
Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Genome, Human/*genetics
Neoplasm Metastasis/*genetics
DNA Mutational Analysis ; Disease Progression ; Female ; Humans ; Male ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Common origin of sequential cutaneous CD30+ lymphoproliferations with nodal involvement evidenced by genome-wide clonal evolution.
Autorzy :
Xerri L; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.
Adélaïde J; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Avenin M; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.; Aix-Marseille University, Marseille, France.
Guille A; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Taix S; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Bonnet N; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Garnier S; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Mescam L; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Murati A; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Coso D; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Bouabdallah R; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Bertucci F; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
Histopathology [Histopathology] 2019 Mar; Vol. 74 (4), pp. 654-662. Date of Electronic Publication: 2019 Jan 31.
Typ publikacji :
Case Reports
MeSH Terms :
Lymph Nodes/*pathology
Lymphoma, Large-Cell, Anaplastic/*pathology
Lymphomatoid Papulosis/*pathology
Skin Neoplasms/*pathology
Clonal Evolution ; Disease Progression ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large-Cell, Anaplastic/genetics ; Lymphomatoid Papulosis/genetics ; Male ; Middle Aged ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Skin Neoplasms/genetics
Raport
Tytuł :
Inflammatory breast cancer in 210 patients: A retrospective study on epidemiological, anatomo-clinical features and therapeutic results.
Autorzy :
Manai M; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Finetti P; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Mejri N; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.
Athimni S; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.
Birnbaum D; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Bertucci F; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.; UFR of Medicine, Aix Marseille University, 13009 Marseille, France.; Department of Medical Oncology, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, Aix Marseille University, 13009 Marseille, France.
Rahal K; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.
Gamoudi A; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.
Chaffanet M; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Manai M; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.
Boussen H; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.; Oncology Radiotherapy Association for the Mediterranean, 75014 Paris, France.
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Źródło :
Molecular and clinical oncology [Mol Clin Oncol] 2019 Feb; Vol. 10 (2), pp. 223-230. Date of Electronic Publication: 2018 Nov 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
CDKN2A/B Deletion and Double-hit Mutations of the MAPK Pathway Underlie the Aggressive Behavior of Langerhans Cell Tumors.
Autorzy :
Xerri L; Department of Bio-Pathology and Tumor Immunology.; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.
Adélaïde J; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Popovici C; Institut Paoli-Calmettes, Marseille.; Department of Oncogenetics.
Garnier S; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Guille A; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Mescam-Mancini L; Department of Bio-Pathology and Tumor Immunology.; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.
Laurent C; Department of Pathology, INSERM U1037, University Institute of Cancer-Oncopole, Toulouse, France.
Brousset P; Department of Pathology, INSERM U1037, University Institute of Cancer-Oncopole, Toulouse, France.
Coze C; Department of Pediatric Oncology and Hematology, CHU Timone, APHM, Marseille.; Aix-Marseille University.
Michel G; Department of Pediatric Oncology and Hematology, CHU Timone, APHM, Marseille.; Aix-Marseille University.
Chaffanet M; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Bouabdallah R; Institut Paoli-Calmettes, Marseille.; Department of Hematology.
Coso D; Institut Paoli-Calmettes, Marseille.; Department of Hematology.
Bertucci F; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Birnbaum D; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2018 Feb; Vol. 42 (2), pp. 150-159.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Deletion*
Biomarkers, Tumor/*genetics
Cyclin-Dependent Kinase Inhibitor p15/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Langerhans Cell Sarcoma/*genetics
MAP Kinase Kinase 1/*genetics
Adolescent ; Adult ; Biopsy ; Cell Proliferation ; Child ; Child, Preschool ; Comparative Genomic Hybridization ; DNA Copy Number Variations ; DNA Mutational Analysis ; Female ; GTP Phosphohydrolases/genetics ; Gene Rearrangement ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; Immunohistochemistry ; Langerhans Cell Sarcoma/enzymology ; Langerhans Cell Sarcoma/pathology ; Langerhans Cell Sarcoma/therapy ; Male ; Membrane Proteins/genetics ; Middle Aged ; Phenotype ; Young Adult
Czasopismo naukowe
Tytuł :
Stromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value.
Autorzy :
Doghri R; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .
Manai M; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. maroua.m@hotmail.com.; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. maroua.m@hotmail.com.; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia. maroua.m@hotmail.com.
Finetti P; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Driss M; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia. .
Agavnian E; Département de Bio-Pathologie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Lopez M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Elghardallou M; Département de Médicine Communautaire, Faculté de Médecine de Sousse, Sousse 4000, Tunisia. .
Charafe-Jauffret E; Département de Bio-Pathologie, Institut Paoli-Calmettes, 13009 Marseille, France.; UFR de Médecine, Aix Marseille Université, 13007 Marseille, France.
Manai M; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia.
Chaffanet M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Birnbaum D; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Mrad K; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .
Bertucci F; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .; UFR de Médecine, Aix Marseille Université, 13007 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2017 Dec 23; Vol. 19 (1). Date of Electronic Publication: 2017 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Myristoylated Alanine-Rich C Kinase Substrate/*metabolism
Ovarian Neoplasms/*metabolism
Ovarian Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Ovarian Epithelial ; Cell Line, Tumor ; Female ; Humans ; Middle Aged ; Multivariate Analysis ; Neoplasms, Glandular and Epithelial/metabolism ; Neoplasms, Glandular and Epithelial/pathology ; Prognosis ; Stromal Cells/metabolism ; Survival Analysis
Czasopismo naukowe

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