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Tytuł :
SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.
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Źródło :
Nature Structural & Molecular Biology. 27(5):438-449
Czasopismo naukowe
Tytuł :
A chemogenomic approach to identify personalized therapy for patients with relapse or refractory acute myeloid leukemia: results of a prospective feasibility study
Autorzy :
Collignon, A.
Hospital, M. A.
Montersino, C.
Courtier, F.
Charbonnier, A.
Saillard, C.
D’Incan, E.
Mohty, B.
Guille, A.
Adelaïde, J.
Carbuccia, N.
Garnier, S.
Mozziconacci, M. J.
Zemmour, C.
Pakradouni, J.
Restouin, A.
Castellano, R.
Chaffanet, M.
Birnbaum, D.
Collette, Y.
Vey, N.
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Źródło :
Blood Cancer Journal. 10(6)
Czasopismo naukowe
Tytuł :
Overcoming Resistance to Anti-nectin-4 Antibody-Drug Conjugate.
Autorzy :
Cabaud O; Centre de Recherche en Cancérologie de Marseille-Inserm-UMR1068, Marseille, France.
Berger LGM; Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Crompot E; Centre de Recherche en Cancérologie de Marseille, France.
Adélaide J; Centre de Recherche en Cancérologie de Marseille, CRCM, Marseille, France.
Finetti P; Institute Paoli-Calmettes, Marseille, France.
Garnier S; Institute Paoli-Calmettes, Marseille, France.
Guille A; CRCM, Marseille, France.
Carbuccia N; CRCM, Marseille, France.
Farina A; Centre de Recherche en Cancérologie de Marseille-Inserm-UMR1068, Marseille, France.
Agavnian E; Centre de Recherche en Cancérologie de Marseille-Inserm-UMR1068, Marseille, France.
Chaffanet M; CRCM, Marseille, France.
Gonçalves A; Institute Paoli-Calmettes, France.
Charafe-Jauffret E; CRCM, Marseille, France.
Mamessier E; Cancer research center of Marseille, Marseille, France.
Birmbaum D; Institute Paoli-Calmettes, Marseille, France.
Bertucci F; Institute Paoli-Calmettes, Marseille, France.
Lopez M; Centre de Recherche en Cancérologie de Marseille, Marseille, France.
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Źródło :
Molecular cancer therapeutics [Mol Cancer Ther] 2022 May 09. Date of Electronic Publication: 2022 May 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Molecular Profiles of Advanced Urological Cancers in the PERMED-01 Precision Medicine Clinical Trial.
Autorzy :
Billon E; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Gravis G; Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.
Guille A; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Carbuccia N; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Adelaide J; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Garnier S; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Finetti P; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Denicolaï E; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Sfumato P; Biostatistics Unit, Institut Paoli-Calmettes, 13009 Marseille, France.
Brunelle S; Department of Imaging, Institut Paoli-Calmettes, 13009 Marseille, France.
Thomassin-Piana J; Department of Biopathology, Institut Paoli-Calmettes, 13009 Marseille, France.
Pignot G; Department of Urology, Institut Paoli-Calmettes, 13009 Marseille, France.
Walz J; Department of Urology, Institut Paoli-Calmettes, 13009 Marseille, France.
Chabannon C; Biobank, Department of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Pakradouni J; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, 13009 Marseille, France.
Sabatier R; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Vicier C; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Popovici C; Department of Oncogenetics, Institut Paoli-Calmettes, 13009 Marseille, France.
Mamessier E; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Gonçalves A; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.; Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.
Birnbaum D; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Chaffanet M; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.
Bertucci F; Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 13009 Marseille, France.; Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.
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Źródło :
Cancers [Cancers (Basel)] 2022 May 03; Vol. 14 (9). Date of Electronic Publication: 2022 May 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Author Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.
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Źródło :
Nature Structural & Molecular Biology. 27(6):603-603
Czasopismo naukowe
Tytuł :
Publisher Correction: SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations
Autorzy :
Takedachi, A.Aff1, Aff2, Aff10
Despras, E.
Scaglione, S.
Guérois, R.
Guervilly, J. H.
Blin, M.
Audebert, S.
Camoin, L.
Hasanova, Z.Aff1, Aff11
Schertzer, M.Aff5, Aff6
Guille, A.
Churikov, D.
Callebaut, I.
Naim, V.
Chaffanet, M.
Borg, J. P.
Bertucci, F.
Revy, P.
Birnbaum, D.
Londoño-Vallejo, A.Aff5, Aff6
Kannouche, P. L.
Gaillard, P. H. L.
Pokaż więcej
Źródło :
Nature Structural & Molecular Biology. 27(6):604-604
Czasopismo naukowe
Tytuł :
Circulating tumor DNA predicts efficacy of a dual AKT/p70S6K inhibitor (LY2780301) plus paclitaxel in metastatic breast cancer: plasma analysis of the TAKTIC phase IB/II study.
Autorzy :
Sabatier R; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.; Institut Paoli-Calmettes-Department of Medical Oncology, CRCM, Inserm, CNRS, Aix-Marseille Université, France.
Vicier C; Institut Paoli-Calmettes-Department of Medical Oncology, CRCM, Inserm, CNRS, Aix-Marseille Université, France.
Garnier S; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.
Guille A; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.
Carbuccia N; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.
Isambert N; Drug Development Department, Centre Georges François Leclerc, Dijon, France.
Dalenc F; Department of Medical Oncology, Institut Claudius Regaud, CRCT, Inserm, IUCT-Oncopole, Toulouse, France.
Robert M; Institut de Cancérologie de l'Ouest-René Gauducheau, Saint-Herblain, France.
Levy C; Department of Medical Oncology, Centre François Baclesse, Caen, France.
Pakradouni J; Depatment of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Adelaïde J; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.
Chaffanet M; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.
Sfumato P; Depatment of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Mamessier E; Institut Paoli-Calmettes-Department of Medical Oncology, CRCM, Inserm, CNRS, Aix-Marseille Université, France.
Bertucci F; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.; Institut Paoli-Calmettes-Department of Medical Oncology, CRCM, Inserm, CNRS, Aix-Marseille Université, France.
Goncalves A; CRCM-Predictive Oncology Laboratory, Institut Paoli-Calmettes, Inserm, CNRS, Aix-Marseille Université, France.; Institut Paoli-Calmettes-Department of Medical Oncology, CRCM, Inserm, CNRS, Aix-Marseille Université, France.
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Źródło :
Molecular oncology [Mol Oncol] 2022 Feb 05. Date of Electronic Publication: 2022 Feb 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity.
Autorzy :
Cherif C; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.; Laboratory of Biochemistry and Molecular Biology, Science University of Tunis, 2092, El Manar, Tunis, Tunisia.
Nguyen DT; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Paris C; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Le TK; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Sefiane T; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Carbuccia N; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Finetti P; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Chaffanet M; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Kaoutari AE; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Vernerey J; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Fazli L; The Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.
Gleave M; The Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.
Manai M; Laboratory of Biochemistry and Molecular Biology, Science University of Tunis, 2092, El Manar, Tunis, Tunisia.
Barthélémy P; ARNA Laboratory, INSERM U1212, CNRS UMR 5320, University of Bordeaux, F-33076 Bordeaux, France.
Birnbaum D; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Bertucci F; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.
Taïeb D; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France.; Biophysics and Nuclear Medicine Department, La Timone University Hospital, European Center for Research in Medical Imaging, Aix-Marseille University, F-13005 Marseille, France.
Rocchi P; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Inserm UMR 1068, CNRS UMR 7258, Institut Paoli-Calmettes, Aix-Marseille University, 27 Bd. Leï Roure, F-13009 Marseille, France. .
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Źródło :
Oncogene [Oncogene] 2022 Jan; Vol. 41 (1), pp. 125-137. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genomics/*methods
Prostatic Neoplasms, Castration-Resistant/*genetics
Proto-Oncogene Proteins/*metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation ; Humans ; Male ; Prostatic Neoplasms, Castration-Resistant/pathology
Czasopismo naukowe
Tytuł :
TAKTIC: A prospective, multicentre, uncontrolled, phase IB/II study of LY2780301, a p70S6K/AKT inhibitor, in combination with weekly paclitaxel in HER2-negative advanced breast cancer patients.
Autorzy :
Vicier C; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Sfumato P; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Isambert N; Drug Development Department, Centre Georges François Leclerc, Dijon, France.
Dalenc F; Department of Medical Oncology, Institut Claudius Regaud, IUCT-Oncopole, CRCT, Inserm, Toulouse, France.
Robert M; Institut de Cancérologie de l'Ouest-René Gauducheau, Saint-Herblain, France.
Levy C; Centre François Baclesse, Department of Medical Oncology, Caen, France.
Rezai K; Department of Radio-Pharmacology, Institut Curie, St Cloud, France.
Provansal M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Adélaïde J; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Garnier S; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Guille A; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Carbuccia N; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Popovici C; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Aix Marseille University, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Biopathology Department, CRCM, Marseille, France.
Chaffanet M; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Birnbaum D; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Pakradouni J; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Bertucci F; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Boher JM; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France; Aix Marseille University, INSERM, IRD, SESSTIM, Marseille, France.
Sabatier R; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France.
Gonçalves A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France; Predictive Oncology Laboratory, CRCM, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Univ, Marseille, France. Electronic address: .
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 Dec; Vol. 159, pp. 205-214. Date of Electronic Publication: 2021 Nov 12.
Typ publikacji :
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Enzyme Inhibitors/*administration & dosage
Paclitaxel/*administration & dosage
Triple Negative Breast Neoplasms/*drug therapy
Adult ; Aged ; Female ; Humans ; Middle Aged ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Ribosomal Protein S6 Kinases, 70-kDa/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial.
Autorzy :
Bertucci F; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France. .; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France. .
Gonçalves A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Guille A; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Adelaïde J; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Garnier S; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Carbuccia N; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Billon E; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Finetti P; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Sfumato P; Biostatistics Unit, Institut Paoli-Calmettes, Marseille, France.
Monneur A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Pécheux C; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.
Khran M; Department of Medical genetics, Hôpital Timone Enfants, AP-HM, Marseille, France.; Aix-Marseille University, Inserm, U1251-MMG, Marseille Medical Genetics, Marseille, France.
Brunelle S; Department of Imaging, Institut Paoli-Calmettes, Marseille, France.
Mescam L; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Thomassin-Piana J; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Poizat F; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Turrini O; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Lambaudie E; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Provansal M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Extra JM; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Madroszyk A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Gilabert M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Sabatier R; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Vicier C; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Mamessier E; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chabannon C; Biobank, Department of Hematology, Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; Department of Clinical Research and Innovation, Institut Paoli-Calmettes, Marseille, France.
Viens P; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
André F; Department of Medical Oncology, Gustave Roussy Cancer Campus, UMR981 Inserm, Villejuif, France.; Paris Sud University, Orsay, France.
Gravis G; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Popovici C; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Chaffanet M; Laboratory of Predictive Oncology, Department of Medical Oncology, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille University, 232 Boulevard Sainte-Marguerite, 13009, Marseille, France.
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Źródło :
Genome medicine [Genome Med] 2021 May 18; Vol. 13 (1), pp. 87. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Genomics*/methods
High-Throughput Nucleotide Sequencing*
Neoplasms/*diagnosis
Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Biopsy ; Combined Modality Therapy ; Comparative Genomic Hybridization ; Disease Management ; Disease Susceptibility ; Female ; Genetic Variation ; Humans ; Male ; Middle Aged ; Molecular Diagnostic Techniques/methods ; Molecular Diagnostic Techniques/standards ; Neoplasm Grading ; Neoplasm Staging ; Neoplasms/mortality ; Neoplasms/therapy ; Precision Medicine/methods ; Prognosis ; Prospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Case Report: Two Cases of Metastatic Pancreatoblastoma in Adults: Efficacy of Folfirinox and Implication of the Wnt/β-Catenin Pathway in Genomic Analysis.
Autorzy :
Raoul JL; Department of Medical Oncology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
Oziel-Taieb S; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Lecomte T; Department of Hepatogastroenterology, CHU Tours, Tours, France.
Adelaide J; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Guille A; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Chaffanet M; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Poizat F; Department of Pathology, Institut Paoli-Calmettes, Marseille, France.
Heymann MF; Department of Pathology, Institut de Cancérologie de l'Ouest, Saint-Herblain, France.
Barbier L; Department of Digestive Surgery, CHU Tours, Tours, France.
Bertucci F; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Predictive Oncology Laboratory, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
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Źródło :
Frontiers in oncology [Front Oncol] 2021 Mar 16; Vol. 11, pp. 564506. Date of Electronic Publication: 2021 Mar 16 (Print Publication: 2021).
Typ publikacji :
Case Reports
Raport
Tytuł :
Gains of EPOR and ERG genes in adult erythroleukaemia.
Autorzy :
Adélaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Cervera N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Murati A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Mozziconacci MJ; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Vey N; Hématologie, Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France.
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.
Gelsi-Boyer V; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université UM105, Marseille, France.; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
British journal of haematology [Br J Haematol] 2020 May; Vol. 189 (4), pp. e174-e177. Date of Electronic Publication: 2020 Mar 29.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Erythroblastic, Acute/*genetics
Receptors, Erythropoietin/*genetics
Adult ; Gene Dosage ; Humans ; Prognosis ; Transcriptional Regulator ERG/genetics
Raport
Tytuł :
NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers.
Autorzy :
Bertucci F; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Rypens C; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Finetti P; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Adélaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Monneur A; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Garnier S; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Dirix P; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Gonçalves A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Vermeulen P; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Debeb BG; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Wang X; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dirix L; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
Ueno NT; MD Anderson Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Viens P; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Cristofanilli M; Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA.
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, France.
Van Laere S; Translational Cancer Research Unit and Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences, GZA Hospitals Sint-Augustinus and University of Antwerp Wilrijk, Antwerp, Belgium.
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Źródło :
Molecular oncology [Mol Oncol] 2020 Mar; Vol. 14 (3), pp. 504-519. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
DNA Repair/*genetics
Inflammatory Breast Neoplasms/*genetics
Receptor, Notch4/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Comparative Genomic Hybridization ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase 6/genetics ; DNA Copy Number Variations ; Female ; Genomics ; High-Throughput Nucleotide Sequencing ; Humans ; Inflammatory Breast Neoplasms/mortality ; Inflammatory Breast Neoplasms/pathology ; Middle Aged ; Mutation ; Neoplasm Staging ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
High Response to Cetuximab in a Patient With EGFR -Amplified Heavily Pretreated Metastatic Triple-Negative Breast Cancer.
Autorzy :
Sabatier R; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.; Institut Paoli-Calmettes, Marseille, France.
Lopez M; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Guille A; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Billon E; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Garnier S; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Adelaide J; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Extra JM; Institut Paoli-Calmettes, Marseille, France.
Cappiello MA; Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; Institut Paoli-Calmettes, Marseille, France.
Viens P; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Gonçalves A; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
Bertucci F; Aix-Marseille University, Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, and Institut Paoli-Calmettes, Marseille, France.
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Źródło :
JCO precision oncology [JCO Precis Oncol] 2019 Dec; Vol. 3, pp. 1-8.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Major Response to Carboplatin in a Patient With Metastatic Triple-Negative Breast Cancer With Somatic Mutation of BRCA1 and Loss of RAD51B .
Autorzy :
Seguin L; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Garnier S; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Adélaïde J; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Guille A; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; Institut Paoli-Calmettes, Marseille, France.
Sabatier R; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Popovici C; Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Bertucci F; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
Goncalves A; Aix-Marseille Université, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
JCO precision oncology [JCO Precis Oncol] 2019 Dec; Vol. 3, pp. 1-9.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Author Correction: Genomic characterization of metastatic breast cancers.
Autorzy :
Bertucci F; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France. .
Ng CKY; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Patsouris A; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Droin N; Genomic Core Facility UMS AMMICA Gustave Roussy Cancer Campus, Villejuif, France.; INSERM, US23, Villejuif, France.; CNRS, UMS3665, Villejuif, France.
Piscuoglio S; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.
Carbuccia N; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Soria JC; Université Paris Sud, Orsay, France.; Drug Development Department (DITEP), Gustave Roussy Cancer Campus, Villejuif, France.
Dien AT; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Adnani Y; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Kamal M; Department of Translational Research, Institut Curie, Saint-Cloud, France.
Garnier S; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Meurice G; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Jimenez M; Unicancer, Paris, France.
Dogan S; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Verret B; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Chaffanet M; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Bachelot T; Centre Léon Bérard, Lyon, France.
Campone M; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Lefeuvre C; Centre Eugène Marquis, Rennes, France.
Bonnefoi H; Institut Bergonié, Bordeaux, France.
Dalenc F; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Jacquet A; Unicancer, Paris, France.
De Filippo MR; Institute of Pathology, University Hospital Basel, Basel, Switzerland.
Babbar N; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Birnbaum D; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Filleron T; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Le Tourneau C; Department of Drug Development and Innovation, Institut Curie, Saint-Cloud, France.; INSERM U900, Saint-Cloud, France.; Versailles Saint Quentin en Yvelines University, Montigny le Bretonneux, France.
André F; Université Paris Sud, Orsay, France. .; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France. .; Department of Medical Oncology, Gustave Roussy, Villejuif, France. .
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Źródło :
Nature [Nature] 2019 Aug; Vol. 572 (7767), pp. E7.
Typ publikacji :
Published Erratum
Tytuł :
Targeted molecular characterization shows differences between primary and secondary myelofibrosis.
Autorzy :
Courtier F; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Garnier S; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Carbuccia N; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Guille A; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Adélaide J; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.
Chaffanet M; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Hirsch P; Centre de Recherche Saint-Antoine CRSA, APHP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, Paris, France.
Paz DL; Laboratoire d'Hématologie, CHU d'Angers, Angers, France.
Slama B; Centre Hospitalier Général d'Avignon, Service d'Onco-Hématologie, France.
Vey N; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Aix-Marseille Université, Marseille, France.; Département d'Hématologie, IPC, Marseille, France.
Ugo V; Laboratoire d'Hématologie, CHU d'Angers, Angers, France.
Delhommeau F; Centre de Recherche Saint-Antoine CRSA, APHP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, Paris, France.
Rey J; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Hématologie, IPC, Marseille, France.
Birnbaum D; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Aix-Marseille Université, Marseille, France.
Murati A; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, Marseille, France.; Département d'Oncologie Prédictive, Institut Paoli-Calmettes (IPC), Marseille, France.; Département de BioPathologie, IPC, Marseille, France.
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Źródło :
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2019 Jul 24. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases.
Autorzy :
Tyran M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département de Radiothérapie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Carbuccia N; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Garnier S; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Guille A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Adelaïde J; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Finetti P; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Toulzian J; Département d'Anatomopathologie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Viens P; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
Tallet A; Département de Radiothérapie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Goncalves A; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
Metellus P; Département de Neurochirurgie et de Neuro-oncologie, Hôpital Privé Clairval, Ramsay-Générale de Santé and Institut de Neurophysiopathologie Equipe 10, UMR0751, CNRS, 13009 Marseille, France. .
Birnbaum D; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Chaffanet M; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .
Bertucci F; Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .; Faculté de Médecine, Aix-Marseille Université, 13005 Marseille, France. .
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Źródło :
Cancers [Cancers (Basel)] 2019 May 13; Vol. 11 (5). Date of Electronic Publication: 2019 May 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genomic characterization of metastatic breast cancers.
Autorzy :
Bertucci F; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Ng CKY; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.
Patsouris A; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Droin N; Genomic Core Facility UMS AMMICA Gustave Roussy Cancer Campus, Villejuif, France.; INSERM, US23, Villejuif, France.; CNRS, UMS3665, Villejuif, France.
Piscuoglio S; Institute of Pathology, University Hospital Basel, Basel, Switzerland.; Clarunis, Department of Biomedicine, University of Basel, Basel, Switzerland.
Carbuccia N; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Soria JC; Université Paris Sud, Orsay, France.; Drug Development Department (DITEP), Gustave Roussy Cancer Campus, Villejuif, France.
Dien AT; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Adnani Y; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Kamal M; Department of Translational Research, Institut Curie, Saint-Cloud, France.
Garnier S; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Meurice G; Bioinformatics Core Facility, Gustave Roussy Cancer Campus, Villejuif, France.
Jimenez M; Unicancer, Paris, France.
Dogan S; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Verret B; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France.
Chaffanet M; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Bachelot T; Centre Léon Bérard, Lyon, France.
Campone M; Inserm, U1232, Nantes, France.; Institut de Cancérologie de l'Ouest - René Gauducheau, Saint Herblain, France.
Lefeuvre C; Centre Eugène Marquis, Rennes, France.
Bonnefoi H; Institut Bergonié, Bordeaux, France.
Dalenc F; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Jacquet A; Unicancer, Paris, France.
De Filippo MR; Institute of Pathology, University Hospital Basel, Basel, Switzerland.
Babbar N; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Birnbaum D; CRCM, Predictive Oncology team, Inserm, Aix-Marseille Univ, CNRS, Institut Paoli-Calmettes, Marseille, France.
Filleron T; Institut Claudius-Regaud, IUCT-oncopôle, Toulouse, France.
Le Tourneau C; Department of Drug Development and Innovation, Institut Curie, Saint-Cloud, France.; INSERM U900, Saint-Cloud, France.; Versailles Saint Quentin en Yvelines University, Montigny le Bretonneux, France.
André F; Université Paris Sud, Orsay, France. .; Inserm, Gustave Roussy Cancer Campus, UMR981, Villejuif, France. .; Department of Medical Oncology, Gustave Roussy, Villejuif, France. .
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Źródło :
Nature [Nature] 2019 May; Vol. 569 (7757), pp. 560-564. Date of Electronic Publication: 2019 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Genomics*
Mutation*
Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Genome, Human/*genetics
Neoplasm Metastasis/*genetics
DNA Mutational Analysis ; Disease Progression ; Female ; Humans ; Male ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Common origin of sequential cutaneous CD30+ lymphoproliferations with nodal involvement evidenced by genome-wide clonal evolution.
Autorzy :
Xerri L; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.
Adélaïde J; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Avenin M; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.; Aix-Marseille University, Marseille, France.
Guille A; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Taix S; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Bonnet N; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Garnier S; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Mescam L; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Murati A; Department of Bio-Pathology, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Coso D; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Bouabdallah R; Department of Haematology, Institut Paoli-Calmettes, Marseille, France.
Bertucci F; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Aix-Marseille University, Marseille, France.; Inserm-CNRS, CRCM, Marseille, France.; Department of Predictive Oncology, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
Histopathology [Histopathology] 2019 Mar; Vol. 74 (4), pp. 654-662. Date of Electronic Publication: 2019 Jan 31.
Typ publikacji :
Case Reports
MeSH Terms :
Lymph Nodes/*pathology
Lymphoma, Large-Cell, Anaplastic/*pathology
Lymphomatoid Papulosis/*pathology
Skin Neoplasms/*pathology
Clonal Evolution ; Disease Progression ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large-Cell, Anaplastic/genetics ; Lymphomatoid Papulosis/genetics ; Male ; Middle Aged ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Skin Neoplasms/genetics
Raport
Tytuł :
Inflammatory breast cancer in 210 patients: A retrospective study on epidemiological, anatomo-clinical features and therapeutic results.
Autorzy :
Manai M; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Finetti P; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Mejri N; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.
Athimni S; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.
Birnbaum D; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Bertucci F; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.; UFR of Medicine, Aix Marseille University, 13009 Marseille, France.; Department of Medical Oncology, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, Aix Marseille University, 13009 Marseille, France.
Rahal K; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.
Gamoudi A; Department of Immuno-Histo-Cytology, Salah Azaiez Institute, Tunis 1006, Tunisia.
Chaffanet M; Predictive Oncology Τeam, Marseille Cancer Research Center (INSERM UMR1068; IFR137), Paoli-Calmettes Institute, 13009 Marseille, France.
Manai M; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.
Boussen H; Medical Oncology Service, University Hospital Abderrahmane Mami, Ariana 2080, Tunisia.; Laboratory of Biochemistry and Molecular Biology, Department of Biology, Faculty of Sciences, University of Tunis El Manar, Ariana 2092, Tunisia.; Oncology Radiotherapy Association for the Mediterranean, 75014 Paris, France.
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Źródło :
Molecular and clinical oncology [Mol Clin Oncol] 2019 Feb; Vol. 10 (2), pp. 223-230. Date of Electronic Publication: 2018 Nov 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Poly (ADP-Ribose) Polymerase Inhibitors for De Novo BRCA2-Null Small-Cell Prostate Cancer.
Autorzy :
Chanez B; All authors: Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; All authors: Institut Paoli-Calmettes, Marseille, France.
Adélaide J; All authors: Institut Paoli-Calmettes, Marseille, France.
Thomassin J; All authors: Institut Paoli-Calmettes, Marseille, France.
Garnier S; All authors: Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; All authors: Institut Paoli-Calmettes, Marseille, France.
Guille A; All authors: Institut Paoli-Calmettes, Marseille, France.
Charrier N; All authors: Institut Paoli-Calmettes, Marseille, France.
Brenot-Rossi I; All authors: Institut Paoli-Calmettes, Marseille, France.
Walz J; All authors: Institut Paoli-Calmettes, Marseille, France.
Pignot G; All authors: Institut Paoli-Calmettes, Marseille, France.
Pakradouni J; All authors: Institut Paoli-Calmettes, Marseille, France.
Gonçalvès A; All authors: Institut Paoli-Calmettes, Marseille, France.
Eisinger F; All authors: Institut Paoli-Calmettes, Marseille, France.
Bertucci F; All authors: Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; All authors: Institut Paoli-Calmettes, Marseille, France.
Gravis G; All authors: Institut Paoli-Calmettes, Marseille, France.
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Źródło :
JCO precision oncology [JCO Precis Oncol] 2018 Nov; Vol. 2, pp. 1-8.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Immune-Based Therapy in Triple-Negative Breast Cancer: From Molecular Biology to Clinical Practice.
Autorzy :
Carlino, Francesca (AUTHOR)
Diana, Anna (AUTHOR)
Piccolo, Antonio (AUTHOR)
Ventriglia, Anna (AUTHOR)
Bruno, Vincenzo (AUTHOR)
De Santo, Irene (AUTHOR)
Letizia, Ortensio (AUTHOR)
De Vita, Ferdinando (AUTHOR)
Daniele, Bruno (AUTHOR)
Ciardiello, Fortunato (AUTHOR)
Orditura, Michele (AUTHOR)
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Źródło :
Cancers. May2022, Vol. 14 Issue 9, pN.PAG-N.PAG. 31p.
Czasopismo naukowe
Tytuł :
CDKN2A/B Deletion and Double-hit Mutations of the MAPK Pathway Underlie the Aggressive Behavior of Langerhans Cell Tumors.
Autorzy :
Xerri L; Department of Bio-Pathology and Tumor Immunology.; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.
Adélaïde J; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Popovici C; Institut Paoli-Calmettes, Marseille.; Department of Oncogenetics.
Garnier S; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Guille A; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Mescam-Mancini L; Department of Bio-Pathology and Tumor Immunology.; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.
Laurent C; Department of Pathology, INSERM U1037, University Institute of Cancer-Oncopole, Toulouse, France.
Brousset P; Department of Pathology, INSERM U1037, University Institute of Cancer-Oncopole, Toulouse, France.
Coze C; Department of Pediatric Oncology and Hematology, CHU Timone, APHM, Marseille.; Aix-Marseille University.
Michel G; Department of Pediatric Oncology and Hematology, CHU Timone, APHM, Marseille.; Aix-Marseille University.
Chaffanet M; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Bouabdallah R; Institut Paoli-Calmettes, Marseille.; Department of Hematology.
Coso D; Institut Paoli-Calmettes, Marseille.; Department of Hematology.
Bertucci F; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
Birnbaum D; Cancer Research Center of Marseille (CRCM), INSERM U1068.; CNRS UMR7258.; Institut Paoli-Calmettes, Marseille.; Aix-Marseille University.; Department of Molecular Oncology, Cancer Research Center of Marseille (CRCM).
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2018 Feb; Vol. 42 (2), pp. 150-159.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Deletion*
Biomarkers, Tumor/*genetics
Cyclin-Dependent Kinase Inhibitor p15/*genetics
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Langerhans Cell Sarcoma/*genetics
MAP Kinase Kinase 1/*genetics
Adolescent ; Adult ; Biopsy ; Cell Proliferation ; Child ; Child, Preschool ; Comparative Genomic Hybridization ; DNA Copy Number Variations ; DNA Mutational Analysis ; Female ; GTP Phosphohydrolases/genetics ; Gene Rearrangement ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans ; Immunohistochemistry ; Langerhans Cell Sarcoma/enzymology ; Langerhans Cell Sarcoma/pathology ; Langerhans Cell Sarcoma/therapy ; Male ; Membrane Proteins/genetics ; Middle Aged ; Phenotype ; Young Adult
Czasopismo naukowe
Tytuł :
Stromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value.
Autorzy :
Doghri R; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .
Manai M; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. maroua.m@hotmail.com.; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. maroua.m@hotmail.com.; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia. maroua.m@hotmail.com.
Finetti P; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Driss M; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia. .
Agavnian E; Département de Bio-Pathologie, Institut Paoli-Calmettes, 13009 Marseille, France. .
Lopez M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Elghardallou M; Département de Médicine Communautaire, Faculté de Médecine de Sousse, Sousse 4000, Tunisia. .
Charafe-Jauffret E; Département de Bio-Pathologie, Institut Paoli-Calmettes, 13009 Marseille, France.; UFR de Médecine, Aix Marseille Université, 13007 Marseille, France.
Manai M; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia.
Chaffanet M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Birnbaum D; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .
Mrad K; Département d'Anatomie Pathologique, Institut Salah Azaiez, Bab Saadoun, Tunis 1006, Tunisia. .
Bertucci F; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France. .; UFR de Médecine, Aix Marseille Université, 13007 Marseille, France. .; Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2017 Dec 23; Vol. 19 (1). Date of Electronic Publication: 2017 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Myristoylated Alanine-Rich C Kinase Substrate/*metabolism
Ovarian Neoplasms/*metabolism
Ovarian Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Ovarian Epithelial ; Cell Line, Tumor ; Female ; Humans ; Middle Aged ; Multivariate Analysis ; Neoplasms, Glandular and Epithelial/metabolism ; Neoplasms, Glandular and Epithelial/pathology ; Prognosis ; Stromal Cells/metabolism ; Survival Analysis
Czasopismo naukowe
Tytuł :
An ICGC major achievement in breast cancer: a comprehensive catalog of mutations and mutational signatures.
Autorzy :
Bertucci F; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR1068 INSERM, UMR725 CNRS, Institut PaoliCalmettes(IPC), Marseille, France; Département d'Oncologie Médicale, IPC, Marseille, France; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Chaffanet M; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR1068 INSERM, UMR725 CNRS, Institut PaoliCalmettes(IPC), Marseille, France.
Birnbaum D; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR1068 INSERM, UMR725 CNRS, Institut PaoliCalmettes(IPC), Marseille, France.
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Źródło :
Chinese clinical oncology [Chin Clin Oncol] 2017 Feb; Vol. 6 (1), pp. 4. Date of Electronic Publication: 2016 Nov 09.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Mutation*
Breast Neoplasms/*genetics
DNA Mutational Analysis ; Humans
Opinia redakcyjna
Tytuł :
MARCKS protein overexpression in inflammatory breast cancer.
Autorzy :
Manai M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunisie.; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.; Service d'Oncologie Médicale, Hôpital l'Ariana, Tunis, Tunisie.
Thomassin-Piana J; Département de Bio-Pathologie, Institut Paoli-Calmettes, Marseille, France.
Gamoudi A; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.
Finetti P; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.
Lopez M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.
Eghozzi R; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.
Ayadi S; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.
Lamine OB; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.
Manai M; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunisie.
Rahal K; Département d'Oncologie Médicale, Institut Salah Azaiez, Tunis, Tunisie.
Charafe-Jauffret E; Département de Bio-Pathologie, Institut Paoli-Calmettes, Marseille, France.; UFR de Médecine, Aix Marseille Université, Marseille, France.
Jacquemier J; Département de Bio-Pathologie, Institut Paoli-Calmettes, Marseille, France.
Viens P; UFR de Médecine, Aix Marseille Université, Marseille, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.
Boussen H; Département de Biologie, Unité de Biochimie et Biologie Moléculaire, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunisie.; Service d'Oncologie Médicale, Hôpital l'Ariana, Tunis, Tunisie.
Chaffanet M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.
Bertucci F; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Aix Marseille Université, Marseille, France.; UFR de Médecine, Aix Marseille Université, Marseille, France.; Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
Oncotarget [Oncotarget] 2017 Jan 24; Vol. 8 (4), pp. 6246-6257.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Biomarkers, Tumor/*analysis
Inflammatory Breast Neoplasms/*chemistry
Myristoylated Alanine-Rich C Kinase Substrate/*analysis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Disease-Free Survival ; Female ; France ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Inflammatory Breast Neoplasms/genetics ; Inflammatory Breast Neoplasms/pathology ; Inflammatory Breast Neoplasms/therapy ; Kaplan-Meier Estimate ; Middle Aged ; Multivariate Analysis ; Myristoylated Alanine-Rich C Kinase Substrate/genetics ; Neoplasm Grading ; Neoplasm Metastasis ; Neoplasm Staging ; Proportional Hazards Models ; RNA, Messenger/genetics ; Retrospective Studies ; Risk Factors ; Time Factors ; Treatment Outcome ; Tunisia ; Up-Regulation ; Young Adult
Czasopismo naukowe
Tytuł :
Genomic analysis of myeloproliferative neoplasms in chronic and acute phases.
Autorzy :
Courtier F; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Carbuccia N; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.
Garnier S; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.
Guille A; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.
Adélaïde J; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.
Cervera N; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.
Gelsi-Boyer V; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; IPC, Département de Biopathologie, Marseille, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Mozziconacci MJ; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; IPC, Département de Biopathologie, Marseille, UM 105, Marseille, F-13284, France.
Rey J; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; IPC, Département d'Hématologie, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Vey N; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; IPC, Département d'Hématologie, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Chaffanet M; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Birnbaum D; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France.; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
Murati A; Centre de Recherche en Cancérologie de Marseille, (CRCM), Inserm, U1068, CNRS UMR7258, France .; Institut Paoli-Calmettes (IPC), Département d'Oncologie Moléculaire, UM 105, Marseille, F-13284, France.; IPC, Département de Biopathologie, Marseille, UM 105, Marseille, F-13284, France.; Aix-Marseille Université, UM 105, Marseille, F-13284, France.
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Źródło :
Haematologica [Haematologica] 2017 Jan; Vol. 102 (1), pp. e11-e14. Date of Electronic Publication: 2016 Oct 14.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Genomics*
Mutation*
Cell Transformation, Neoplastic/*genetics
Hematologic Neoplasms/*genetics
Myeloproliferative Disorders/*genetics
Neoplasm Proteins/*genetics
Acute Disease ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; Chronic Disease ; Female ; Hematologic Neoplasms/metabolism ; Hematologic Neoplasms/pathology ; Humans ; Male ; Myeloproliferative Disorders/metabolism ; Myeloproliferative Disorders/pathology ; Neoplasm Proteins/metabolism
Raport
Tytuł :
Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study.
Autorzy :
Gonçalves A; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.
Bertucci F; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Guille A; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Garnier S; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Adelaide J; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Carbuccia N; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Cabaud O; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Finetti P; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Brunelle S; Department of Imaging, Institut Paoli-Calmettes, Marseille, France.
Piana G; Department of Imaging, Institut Paoli-Calmettes, Marseille, France.
Tomassin-Piana J; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Paciencia M; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Lambaudie E; Department of Surgical Oncology, Institut Paoli-Calmettes, Marseille, France.
Popovici C; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Sabatier R; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Tarpin C; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Provansal M; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Extra JM; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.
Eisinger F; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Sobol H; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Oncogenetics, Institut Paoli-Calmettes, Marseille, France.
Viens P; Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.
Lopez M; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Ginestier C; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.; Department of Biopathology, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Aix Marseille Univ, CNRS U7258, INSERM U1068, Institut Paoli-Calmettes, CRCM, Marseille, France.; Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.
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Źródło :
Oncotarget [Oncotarget] 2016 Nov 29; Vol. 7 (48), pp. 79428-79441.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Breast Neoplasms/*pathology
Comparative Genomic Hybridization/*methods
High-Throughput Nucleotide Sequencing/*methods
Precision Medicine/*methods
Sequence Analysis, DNA/*methods
Adult ; Aged ; Animals ; Breast Neoplasms/genetics ; Disease Models, Animal ; Female ; Gene Regulatory Networks ; Genetic Variation ; Humans ; Mice ; Middle Aged ; Neoplasm Transplantation ; Pilot Projects ; Prospective Studies
Czasopismo naukowe
Tytuł :
Epigenetically centered evolution in an example of myeloid malignancy.
Autorzy :
Adélaide J; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Cervera N; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Carbuccia N; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Garnier S; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Guille A; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Mozziconnaci MJ; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Devillier R; Aix-Marseille Université, Marseille, France.; Département d'Hématologie, Institut Paoli-Calmettes, Marseille, France.
Chaffanet M; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Vey N; Aix-Marseille Université, Marseille, France.; Département d'Hématologie, Institut Paoli-Calmettes, Marseille, France.
Birnbaum D; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.
Gelsi-Boyer V; Centre de Recherche en Cancérologie de Marseille, Laboratoire D'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, CNRS UMR725, Marseille, France.; Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.; Aix-Marseille Université, Marseille, France.
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Źródło :
American journal of hematology [Am J Hematol] 2016 Sep; Vol. 91 (9), pp. E361-2. Date of Electronic Publication: 2016 Jul 04.
Typ publikacji :
Case Reports; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Epigenesis, Genetic*
Cell Transformation, Neoplastic/*genetics
Cell Transformation, Neoplastic/*pathology
Myeloproliferative Disorders/*diagnosis
Myeloproliferative Disorders/*genetics
Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Bone Marrow/pathology ; Comparative Genomic Hybridization ; Disease Progression ; Humans ; Immunophenotyping ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Male ; Mutation ; Myeloproliferative Disorders/drug therapy ; Translocation, Genetic ; Treatment Outcome
Raport
Tytuł :
Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway.
Autorzy :
Zhang, Xuehong (AUTHOR)
Wang, Furong (AUTHOR)
Yan, Fanzhi (AUTHOR)
Huang, Dan (AUTHOR)
Wang, Haina (AUTHOR)
Gao, Beibei (AUTHOR)
Gao, Yuan (AUTHOR)
Hou, Zhijie (AUTHOR)
Lou, Jiacheng (AUTHOR)
Li, Weiling (AUTHOR)
Yan, Jinsong (AUTHOR)
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Źródło :
Cancer Cell International. 1/26/2022, Vol. 22 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł :
Comparative genomic analysis of primary tumors and metastases in breast cancer.
Autorzy :
Bertucci F; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Finetti P; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Guille A; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Adélaïde J; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Garnier S; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Carbuccia N; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Monneur A; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.
Charafe-Jauffret E; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.; Département de Biopathologie, CRCM, Institut Paoli-Calmettes, Marseille, France.
Goncalves A; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Viens P; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Birnbaum D; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Chaffanet M; Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
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Źródło :
Oncotarget [Oncotarget] 2016 May 10; Vol. 7 (19), pp. 27208-19.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Copy Number Variations*
Gene Amplification*
Mutation*
Breast Neoplasms/*genetics
Comparative Genomic Hybridization/*methods
Genetic Predisposition to Disease/*genetics
Adult ; Aged ; Antineoplastic Agents/therapeutic use ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cluster Analysis ; Genomics/methods ; Genotype ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Middle Aged ; Molecular Targeted Therapy ; Neoplasm Metastasis
Czasopismo naukowe
Tytuł :
Expression of Genes with Copy Number Alterations and Survival of Patients with Pancreatic Adenocarcinoma.
Autorzy :
Birnbaum DJ; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France Department of Digestive Surgery, North Hospital, Marseille, France Aix-Marseille University, Marseille, France .
Bertucci F; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France Aix-Marseille University, Marseille, France Department of Medical Oncology, Paoli-Calmettes Instituet, Marseille, France.
Finetti P; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Adélaïde J; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Giovannini M; Department of Gastroenterology, Paoli-Calmettes Instituet, Marseille, France.
Turrini O; Aix-Marseille University, Marseille, France Department of Digestive and Oncologic Surgery, Marseille Research Center of Cancerology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Delpero JR; Aix-Marseille University, Marseille, France Department of Digestive and Oncologic Surgery, Marseille Research Center of Cancerology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Raoul JL; Aix-Marseille University, Marseille, France Department of Medical Oncology, Paoli-Calmettes Instituet, Marseille, France.
Chaffanet M; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Moutardier V; Department of Digestive Surgery, North Hospital, Marseille, France Aix-Marseille University, Marseille, France.
Birnbaum D; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France.
Mamessier E; Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France Aix-Marseille University, Marseille, France.
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Źródło :
Cancer genomics & proteomics [Cancer Genomics Proteomics] 2016 May-Jun; Vol. 13 (3), pp. 191-200.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Copy Number Variations*
Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*genetics
Adenocarcinoma/*mortality
Pancreatic Neoplasms/*genetics
Pancreatic Neoplasms/*mortality
Adolescent ; Adult ; Aged ; Apoptosis/genetics ; Cell Cycle/genetics ; Comparative Genomic Hybridization ; Computational Biology/methods ; Databases, Genetic ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Pancreatic Neoplasms/pathology ; Prognosis ; Young Adult
Czasopismo naukowe
Tytuł :
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer.
Autorzy :
Puvirajesinghe TM; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.
Bertucci F; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Jain A; Molecular Cancer Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø 9037, Norway.; Department of Molecular Cell Biology, Centre for Cancer Biomedicine, University of Oslo and Institute for Cancer Research, The Norwegian Radium Hospital, Oslo N-0310, Norway.
Scerbo P; Institut de Biologie du Développement de Marseille, Aix-Marseille Université, CNRS UMR 7288, Marseille F-13288, France.
Belotti E; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.
Audebert S; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Marseille Proteomics Platform, Inserm, U1068, Marseille F-13009, France.
Sebbagh M; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.
Lopez M; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Brech A; Department of Molecular Cell Biology, Centre for Cancer Biomedicine, University of Oslo and Institute for Cancer Research, The Norwegian Radium Hospital, Oslo N-0310, Norway.
Finetti P; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Charafe-Jauffret E; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Chaffanet M; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Castellano R; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, TrGET Platform, Inserm, U1068, Marseille F-13009, France.
Restouin A; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, TrGET Platform, Inserm, U1068, Marseille F-13009, France.
Marchetto S; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.
Collette Y; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, TrGET Platform, Inserm, U1068, Marseille F-13009, France.
Gonçalvès A; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Marseille Proteomics Platform, Inserm, U1068, Marseille F-13009, France.
Macara I; Department of Microbiology, University of Virginia School of Medicine, Charlottesville, Virginia, Tennessee 37240-7935, USA.
Birnbaum D; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Molecular Oncology 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.
Kodjabachian L; Institut de Biologie du Développement de Marseille, Aix-Marseille Université, CNRS UMR 7288, Marseille F-13288, France.
Johansen T; Molecular Cancer Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø 9037, Norway.
Borg JP; CRCM, Cell Polarity, Cell signalling and Cancer 'Equipe labellisée Ligue Contre le Cancer', Inserm, U1068, Marseille F-13009, France.; Institut Paoli-Calmettes, Marseille F-13009, France.; Aix-Marseille Université, Marseille F-13284, France.; CNRS, UMR725, Marseille F-13009, France.; CRCM, Marseille Proteomics Platform, Inserm, U1068, Marseille F-13009, France.
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Źródło :
Nature communications [Nat Commun] 2016 Jan 12; Vol. 7, pp. 10318. Date of Electronic Publication: 2016 Jan 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing/*genetics
Breast Neoplasms/*genetics
Carcinoma, Ductal, Breast/*genetics
Carcinoma, Lobular/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
MAP Kinase Signaling System/*genetics
Membrane Proteins/*genetics
RNA, Messenger/*metabolism
Wnt Signaling Pathway/*genetics
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Blotting, Western ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/metabolism ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Lobular/metabolism ; Carcinoma, Lobular/pathology ; Cell Line, Tumor ; Cell Migration Assays ; Cell Movement/genetics ; Cell Polarity ; Cell Proliferation/genetics ; DNA Copy Number Variations ; Embryo, Nonmammalian ; Female ; Humans ; Immunoprecipitation ; Intracellular Signaling Peptides and Proteins/metabolism ; Mass Spectrometry ; Membrane Proteins/metabolism ; Mice ; Microscopy, Electron ; Middle Aged ; Neoplasm Transplantation ; Prognosis ; Proportional Hazards Models ; Sequestosome-1 Protein ; Xenopus
Czasopismo naukowe
Tytuł :
pH-Cleavable Nucleoside Lipids: A New Paradigm for Controlling the Stability of Lipid-Based Delivery Systems.
Autorzy :
Oumzil K; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France.
Benizri S; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France.
Tonelli G; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France.
Staedel C; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France.
Appavoo A; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France.
Chaffanet M; INSERM UMR1068-CNRS UMR725, Institut Paoli-Calmettes, 232 Boulevard Sainte Marguerite, 13273, Marseille, France.; Faculté de Médecine, Aix Marseille Université, 27 Boulevard Jean Moulin, 13385, Marseille, France.
Navailles L; Centre de recherche Paul Pascal/UPR 8641, CNRS-Université Bordeaux, 115 Avenue Dr Schweitzer, 33600, Pessac, France.
Barthélémy P; ARNA laboratory-INSERM U869, Université Bordeaux Segalen, 146 Rue Léo Saignat, 33000, Bordeaux, France. .
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Źródło :
ChemMedChem [ChemMedChem] 2015 Nov; Vol. 10 (11), pp. 1797-801. Date of Electronic Publication: 2015 Sep 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Delivery Systems*
Lipids/*chemistry
Liposomes/*chemistry
Nucleosides/*chemistry
Humans ; Hydrogen-Ion Concentration ; Lipids/chemical synthesis ; Liposomes/chemical synthesis
Czasopismo naukowe
Tytuł :
Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study.
Autorzy :
Sicklick, Jason K. (AUTHOR)
Kato, Shumei (AUTHOR)
Okamura, Ryosuke (AUTHOR)
Patel, Hitendra (AUTHOR)
Nikanjam, Mina (AUTHOR)
Fanta, Paul T. (AUTHOR)
Hahn, Michael E. (AUTHOR)
De, Pradip (AUTHOR)
Williams, Casey (AUTHOR)
Guido, Jessica (AUTHOR)
Solomon, Benjamin M. (AUTHOR)
McKay, Rana R. (AUTHOR)
Krie, Amy (AUTHOR)
Boles, Sarah G. (AUTHOR)
Ross, Jeffrey S. (AUTHOR)
Lee, J. Jack (AUTHOR)
Leyland-Jones, Brian (AUTHOR)
Lippman, Scott M. (AUTHOR)
Kurzrock, Razelle (AUTHOR)
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Źródło :
Genome Medicine. 10/4/2021, Vol. 13 Issue 1, p1-14. 14p.
Czasopismo naukowe
Tytuł :
Clinical impact of PD-L1 expression in triple-negative breast cancer patients with residual tumor burden after neoadjuvant chemotherapy.
Autorzy :
Oner, Gizem (AUTHOR)
Önder, Semen (AUTHOR)
Karatay, Hüseyin (AUTHOR)
Ak, Naziye (AUTHOR)
Tükenmez, Mustafa (AUTHOR)
Müslümanoğlu, Mahmut (AUTHOR)
İğci, Abdullah (AUTHOR)
Dincçağ, Ahmet (AUTHOR)
Özmen, Vahit (AUTHOR)
Aydiner, Adnan (AUTHOR)
Yavuz, Ekrem (AUTHOR)
Cabioğlu, Neslihan (AUTHOR)
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Źródło :
World Journal of Surgical Oncology. 9/2/2021, Vol. 19 Issue 1, p1-9. 9p.
Czasopismo naukowe
Tytuł :
Prognostic and predictive value of PDL1 expression in breast cancer.
Autorzy :
Sabatier R; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Finetti P; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Mamessier E; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Adelaide J; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Chaffanet M; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Ali HR; Department of Pathology, University of Cambridge, Cambridge, United Kingdom.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
Viens P; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Caldas C; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
Birnbaum D; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.
Bertucci F; Département d'Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.; Département d'Oncologie Médicale, CRCM, Institut Paoli-Calmettes, Marseille, France.; Faculté de Médecine, Aix-Marseille Université, Marseille, France.
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Źródło :
Oncotarget [Oncotarget] 2015 Mar 10; Vol. 6 (7), pp. 5449-64.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B7-H1 Antigen/*genetics
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
Carcinoma, Ductal, Breast/*genetics
Carcinoma, Lobular/*genetics
Carcinoma, Medullary/*genetics
Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/mortality ; Carcinoma, Ductal, Breast/secondary ; Carcinoma, Lobular/mortality ; Carcinoma, Lobular/secondary ; Carcinoma, Medullary/mortality ; Carcinoma, Medullary/secondary ; Comparative Genomic Hybridization ; Female ; Follow-Up Studies ; Gene Expression Profiling ; Humans ; Lymphatic Metastasis ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness ; Neoplasm Staging ; Oligonucleotide Array Sequence Analysis ; Prognosis ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome.
Autorzy :
El Helou R; CRCM, Molecular Oncology, 'Equipe labellisée Ligue Contre le Cancer,' Inserm, U1068, Marseille, France; Institut Paoli-Calmettes, Marseille, France; Aix-Marseille Université, Marseille, France; CNRS, UMR7258, Marseille, France.
Wicinski J
Guille A
Adélaïde J
Finetti P
Bertucci F
Chaffanet M
Birnbaum D
Charafe-Jauffret E
Ginestier C
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Źródło :
Stem cells (Dayton, Ohio) [Stem Cells] 2014 Nov; Vol. 32 (11), pp. 3031-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*metabolism
Cell Differentiation/*genetics
Cell Transformation, Neoplastic/*genetics
DNA Methylation/*physiology
Neoplastic Stem Cells/*metabolism
Embryonic Stem Cells/metabolism ; Epigenesis, Genetic/physiology ; Female ; Humans ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł :
Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization.
Autorzy :
Sabatier R
Finetti P
Guille A
Adelaide J
Chaffanet M
Viens P
Birnbaum D
Bertucci F; Department of Molecular Oncology, Centre de Recherche en Cancérologie de Marseille, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Marseille, France. .
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Źródło :
Molecular cancer [Mol Cancer] 2014 Oct 02; Vol. 13, pp. 228. Date of Electronic Publication: 2014 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*genetics
Breast Neoplasms/*pathology
Claudins/*metabolism
Breast Neoplasms/classification ; Breast Neoplasms/metabolism ; Claudins/genetics ; Disease-Free Survival ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genome, Human/genetics ; Humans ; Middle Aged ; Odds Ratio ; Prognosis ; Proportional Hazards Models ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation.
Autorzy :
Murati, A.
Gelsi-Boyer, V.
Adélaïde, J.
Perot, C.
Talmant, P.
Giraudier, S.
Lodé, L.
Letessier, A.
Delaval, B.
Brunel, V.
Imbert, M.
Garand, R.
Xerri, L.
Birnbaum, D.
Mozziconacci, M. J.
Chaffanet, M.
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Temat :
LETTERS to the editor
MYELOPROLIFERATIVE neoplasms
Źródło :
Leukemia (08876924); Sep2005, Vol. 19 Issue 9, p1692-1696, 5p
Czasopismo naukowe
Tytuł :
Multicolour-banding fluorescence in situ hybridisation (mbanding-FISH) to identify recurrent chromosomal alterations in breast tumour cell lines.
Autorzy :
Letessier, A.
Mozziconacci, M.-J.
Murati, A.
Juriens, J.
Adélaïde, J.
Birnbaum, D.
Chaffanet, M.
Adélaïde, J
Pokaż więcej
Temat :
TUMORS
CANCER cells
FLUORESCENCE microscopy
CELL culture
CELL lines
GENETICS
RESEARCH
RESEARCH methodology
KARYOTYPES
MEDICAL cooperation
EVALUATION research
COMPARATIVE studies
FLUORESCENCE in situ hybridization
CHROMOSOME abnormalities
BREAST tumors
Źródło :
British Journal of Cancer; 1/31/2005, Vol. 92 Issue 2, p382-388, 7p
Czasopismo naukowe
Tytuł :
Amplification and Expression of Viral Sequences and Oncogenes in Human Brain Tumors
Autorzy :
Benabid, A. L.
Chauvin, C.
Foote, A. M.
Suh, M.
Danik, M.
Laine, M.
Chaffanet, M.
Mercier, C.
Rost, N.
Pokaż więcej
Źródło :
Brain Oncology Biology, diagnosis and therapy : An international meeting on brain oncology, Rennes, France, September 4–5, 1986, held under the auspices of the Ministry of National Education, the University of Rennes and the Regional Hospital Rennes. 52:15-19
Książka elektroniczna
Tytuł :
Early lesions of follicular lymphoma: a genetic perspective.
Autorzy :
Mamessier E; .
Song JY
Eberle FC
Pack S
Drevet C
Chetaille B
Abdullaev Z
Adelaïde J
Birnbaum D
Chaffanet M
Pittaluga S
Roulland S
Chott A
Jaffe ES
Nadel B
Pokaż więcej
Źródło :
Haematologica [Haematologica] 2014 Mar; Vol. 99 (3), pp. 481-8. Date of Electronic Publication: 2013 Oct 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transformation, Neoplastic/*genetics
Lymphoma, Follicular/*genetics
Lymphoma, Follicular/*pathology
Carcinoma in Situ/genetics ; Carcinoma in Situ/pathology ; Comparative Genomic Hybridization ; Disease Progression ; Genomic Instability ; Germinal Center/pathology ; Humans ; Neoplasm Grading ; Neoplasm Staging
Czasopismo naukowe
Tytuł :
Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling.
Autorzy :
Cornen S; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Guille A; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Adélaïde J; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Addou-Klouche L; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France ; Biotoxicology Laboratory, Djillali Liabes University, Sidi-Bel-Abbès, Algeria.
Finetti P; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Saade MR; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Manai M; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France ; Biochemistry and Molecular Biology Unit, Biology Dpt, Faculty of Sciences El Manar, Tunis, Tunisia.
Carbuccia N; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Bekhouche I; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Letessier A; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Raynaud S; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Charafe-Jauffret E; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France ; Institut Paoli-Calmettes (IPC), Department of Biopathology, Marseille, France ; Aix-Marseille Université, Marseille, France.
Jacquemier J; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France ; Institut Paoli-Calmettes (IPC), Department of Biopathology, Marseille, France.
Spicuglia S; Aix-Marseille Université, Marseille, France ; Inserm U1090, TAGC, Marseille, France.
de The H; UMR 944/7212 INSERM/CNRS/Université Paris 7, Hôpital St Louis, Paris, France.
Viens P; Aix-Marseille Université, Marseille, France ; Institut Paoli-Calmettes (IPC), Department of Medical Oncology, Marseille, France.
Bertucci F; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France ; Aix-Marseille Université, Marseille, France ; Institut Paoli-Calmettes (IPC), Department of Medical Oncology, Marseille, France.
Birnbaum D; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
Chaffanet M; Marseille Cancer Research Center, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Department of Molecular Oncology, Equipe labellisée Ligue Contre le Cancer, Marseille, France.
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Źródło :
PloS one [PLoS One] 2014 Jan 09; Vol. 9 (1), pp. e81843. Date of Electronic Publication: 2014 Jan 09 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation, Neoplastic*
Genetic Association Studies*
DNA Methylation/*genetics
Genes, Neoplasm/*genetics
Genome, Human/*genetics
Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Chromosomes, Human, Pair 6/genetics ; DNA Copy Number Variations/genetics ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Kaplan-Meier Estimate ; Meta-Analysis as Topic ; Multivariate Analysis ; Mutation/genetics ; Promoter Regions, Genetic/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RecQ Helicases/genetics ; RecQ Helicases/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Array comparative genomic hybridization and sequencing of 23 genes in 80 patients with myelofibrosis at chronic or acute phase.
Autorzy :
Brecqueville M; .
Rey J
Devillier R
Guille A
Gillet R
Adélaide J
Gelsi-Boyer V
Arnoulet C
Chaffanet M
Mozziconacci MJ
Vey N
Birnbaum D
Murati A
Pokaż więcej
Źródło :
Haematologica [Haematologica] 2014 Jan; Vol. 99 (1), pp. 37-45. Date of Electronic Publication: 2013 Aug 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Primary Myelofibrosis/*genetics
Primary Myelofibrosis/*pathology
Adult ; Aged ; Aged, 80 and over ; Cell Transformation, Neoplastic/genetics ; Chromosome Deletion ; Comparative Genomic Hybridization ; DNA Copy Number Variations ; Disease Progression ; Female ; Genetic Association Studies ; Humans ; Male ; Middle Aged ; Mutation ; Primary Myelofibrosis/diagnosis ; Primary Myelofibrosis/mortality ; Prognosis ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program.
Autorzy :
Charafe-Jauffret E; Authors' Affiliations: INSERM, U1068, CRCM, Molecular Oncology, Institut Paoli-Calmettes, Biopathology, Aix-Marseille Univ, UM 105, F-13284, Départements d'Oncologie Médicale, Chirugie oncologique, and Radiologie, Institut Paoli-Calmettes, Marseille; and Plateforme ARN interference PArI, CEA SACLAY, Gif-sur-Yvette, France.
Ginestier C
Bertucci F
Cabaud O
Wicinski J
Finetti P
Josselin E
Adelaide J
Nguyen TT
Monville F
Jacquemier J
Thomassin-Piana J
Pinna G
Jalaguier A
Lambaudie E
Houvenaeghel G
Xerri L
Harel-Bellan A
Chaffanet M
Viens P
Birnbaum D
Pokaż więcej
Źródło :
Cancer research [Cancer Res] 2013 Dec 15; Vol. 73 (24), pp. 7290-300. Date of Electronic Publication: 2013 Oct 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*enzymology
Breast Neoplasms/*pathology
Isoenzymes/*metabolism
Neoplastic Stem Cells/*enzymology
Retinal Dehydrogenase/*metabolism
Aldehyde Dehydrogenase 1 Family ; Animals ; Biomarkers, Tumor/genetics ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Cell Differentiation/genetics ; Female ; Gene Expression Profiling ; Heterografts ; Humans ; Isoenzymes/genetics ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplastic Stem Cells/pathology ; Nucleic Acid Hybridization ; Prognosis ; Prospective Studies ; Retinal Dehydrogenase/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Signaling pathway switch in breast cancer.
Autorzy :
Guille A; Centre de Recherche en Cancérologie de Marseille, Oncologie Moléculaire, 'Equipe labellisée Ligue Contre le Cancer', UMR1068 Inserm, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, 27 bd, Leï Roure, BP 30059, Marseille 13273, France. .
Chaffanet M
Birnbaum D
Pokaż więcej
Źródło :
Cancer cell international [Cancer Cell Int] 2013 Jun 27; Vol. 13 (1), pp. 66. Date of Electronic Publication: 2013 Jun 27.
Typ publikacji :
Journal Article
Czasopismo naukowe

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