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Tytuł:
Chromosomal analysis of clonally related B-cell lymphomas with discordant immunoglobulin light-chain restrictions at different anatomical sites.
Autorzy:
Nonaka K; Division of Aging and Carcinogenesis, Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan.
Kurata M; Department of Comprehensive Pathology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Tachibana M; Department of Chemotherapy, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Tokyo, Japan.
Komatsu A; Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Tokyo, Japan.
Shichi Y; Division of Aging and Carcinogenesis, Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan.
Gomi F; Division of Aging and Carcinogenesis, Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan.
Ishiwata T; Division of Aging and Carcinogenesis, Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan.
Miyamoto K; Department of Chemotherapy, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Tokyo, Japan.
Arai T; Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Tokyo, Japan.
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Źródło:
Pathology international [Pathol Int] 2023 Feb; Vol. 73 (2), pp. 100-102. Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:
Letter
MeSH Terms:
Immunoglobulin Light Chains*
Lymphoma, B-Cell*/pathology
Humans ; Immunoglobulin kappa-Chains ; Immunoglobulin lambda-Chains/analysis
Opinia redakcyjna
Tytuł:
Identification and genetic analysis of rare variants in myosin family genes in 412 Han Chinese congenital heart disease patients.
Autorzy:
Zhang Y; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, State Key Laboratory of Genetic Engineering at School of Life Sciences, Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Peng R; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, State Key Laboratory of Genetic Engineering at School of Life Sciences, Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.; NHC Key Lab of Reproduction (Shanghai Institute of Planned Parenthood Research), Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai, China.
Wang H; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, State Key Laboratory of Genetic Engineering at School of Life Sciences, Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.; NHC Key Lab of Reproduction (Shanghai Institute of Planned Parenthood Research), Collaborative Innovation Center of Genetics and Development, Fudan University, Shanghai, China.; Children's Hospital, Fudan University, Shanghai, China.; The Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
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Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2022 Oct; Vol. 10 (10), pp. e2041. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heart Defects, Congenital*/genetics
Myosin Light Chains*/genetics
Animals ; China ; Morpholinos ; Myosin Heavy Chains ; Zebrafish/genetics
Czasopismo naukowe
Tytuł:
Antibody production relies on the tRNA inosine wobble modification to meet biased codon demand.
Autorzy:
Giguère S; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Wang X; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Huber S; Department of Biological Engineering, MIT, Cambridge, MA 02139, USA.
Xu L; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Warner J; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Weldon SR; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Hu J; Department of Biological Engineering, MIT, Cambridge, MA 02139, USA.
Phan QA; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Tumang K; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Prum T; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Ma D; BioMicro Center, MIT, Cambridge, MA 02139, USA.
Kirsch KH; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Nair U; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.
Dedon P; Department of Biological Engineering, MIT, Cambridge, MA 02139, USA.; Singapore-MIT Alliance for Research and Technology, Singapore 138602.
Batista FD; The Ragon Institute of Mass General, Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA.; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.; Department of Biology, MIT, Cambridge, MA 02139, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Jan 12; Vol. 383 (6679), pp. 205-211. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antibody Formation*/genetics
Codon Usage*
Inosine*/genetics
Inosine*/metabolism
RNA, Transfer*/genetics
Antibodies*/genetics
B-Lymphocytes*/immunology
Immunoglobulin Heavy Chains*/genetics
Codon/genetics ; Humans
Czasopismo naukowe
Tytuł:
Evaluation of free light chains of immunoglobulins in normal and pathological seminal fluids: Preliminary data.
Autorzy:
Basile U; Dipartimento di Scienze di laboratorio e Infettivologiche, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Vergani E; Dipartimento di Medicina e Chirurgia Traslazionale, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Napodano C; Synlab Italia srl, Monza (MB), Italy.
Bruno C; Dipartimento di Medicina e Chirurgia Traslazionale, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Marino M; Dipartimento di Medicina e Chirurgia Traslazionale, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Oliva A; Dipartimento di Medicina e Chirurgia Traslazionale, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Gulli F; Laboratorio di Patologia Clinica, Ospedale Madre Giuseppina Vannini, Rome, Italy.
Mancini A; Dipartimento di Medicina e Chirurgia Traslazionale, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
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Źródło:
Andrologia [Andrologia] 2022 Mar; Vol. 54 (2), pp. e14317. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Light Chains*
Immunoglobulin lambda-Chains*
Adolescent ; Adult ; Bodily Secretions ; Humans ; Immunoglobulin kappa-Chains ; Male ; Middle Aged ; Preliminary Data ; Young Adult
Czasopismo naukowe
Tytuł:
Effect of bovine myosin heavy chain 3 on proliferation and differentiation of myoblast.
Autorzy:
Tang J; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Yang B; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Song G; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Zhang X; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Wang Z; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Mo Z; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Zan L; College of Animal Science and Technology, Northwest A&F University, Yangling, China.; National Beef Cattle Improvement Center, Yangling, China.
Wang H; College of Animal Science and Technology, Northwest A&F University, Yangling, China.; National Beef Cattle Improvement Center, Yangling, China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (9), pp. 4337-4346. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Myosin Heavy Chains*/genetics
Myoblasts*
Cattle ; Animals ; Cell Differentiation/genetics ; Cell Proliferation ; Muscle Development/genetics
Czasopismo naukowe
Tytuł:
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway.
Autorzy:
Xie Y; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Luo Z; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Peng W; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Liu Y; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yuan F; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Xu J; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Sun Y; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Lu H; Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.; Hunan Engineering Research Center of Sports and Health, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Wu T; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. .; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. .; Hunan Engineering Research Center of Sports and Health, Changsha, China. .; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. .
Jiang L; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. .; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. .; Hunan Engineering Research Center of Sports and Health, Changsha, China. .; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. .
Hu J; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. .; Key Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China. .; Hunan Engineering Research Center of Sports and Health, Changsha, China. .; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Nov 11; Vol. 20 (1), pp. 259. Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Myosin Light Chains*/metabolism
Spinal Cord Injuries*/metabolism
Animals ; Mice ; Rats ; Blood-Brain Barrier/metabolism ; Endothelial Cells/metabolism ; Histone Demethylases/genetics ; Myosin-Light-Chain Kinase/metabolism ; Permeability ; Phosphorylation ; Rats, Sprague-Dawley ; Spinal Cord/metabolism
Czasopismo naukowe
Tytuł:
MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine manner.
Autorzy:
Deng S; Center for Liver Transplantation, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cheng D; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wang J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Gu J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Xue Y; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Jiang Z; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Qin L; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Mao F; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cao Y; Department of Digestive Surgical Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
Cai K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Nov 06; Vol. 42 (1), pp. 294. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/pathology
Myosin Light Chains*/genetics
Animals ; Cell Line, Tumor ; Cell Proliferation ; Fibroblasts/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Transcription Factors/metabolism ; Transforming Growth Factor beta1/metabolism ; Tumor Microenvironment ; Humans
Czasopismo naukowe
Tytuł:
A case of light chain deposition disease involving the kidney with a normal serum free kappa/lambda light chain ratio.
Autorzy:
Zhang S; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
Ni H; Department of Nephrology, Zhongda Hospital Southeast University, Nanjing, China.
Xu Q; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
Cai X; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
Li H; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
Wei Z; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
Cao J; Department of Nephrology, Taixing People's Hospital, Taizhou, China.
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Źródło:
Renal failure [Ren Fail] 2022 Dec; Vol. 44 (1), pp. 103-105.
Typ publikacji:
Case Reports; Letter; Video-Audio Media
MeSH Terms:
Immunoglobulin Light Chains/*blood
Kidney Diseases/*blood
Paraproteinemias/*blood
Diagnosis, Differential ; Female ; Humans ; Immunoglobulin kappa-Chains/blood ; Immunoglobulin lambda-Chains/blood ; Kidney Diseases/drug therapy ; Kidney Function Tests ; Middle Aged ; Paraproteinemias/drug therapy
Raport
Tytuł:
HLA-DRB1*04:05 is involved in the development of Vogt-Koyanagi-Harada disease-like immune-related adverse events in patients receiving immune checkpoint inhibitors.
Autorzy:
Takeuchi M; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. .
Meguro A; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Nakamura J; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Chikagawa R; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Osada R; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Shibuya E; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Hasumi Y; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Yamada N; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Ishihara M; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Mizuki N; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 21; Vol. 13 (1), pp. 13580. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:
Journal Article
MeSH Terms:
HLA-DRB1 Chains*/genetics
HLA-DRB1 Chains*/metabolism
Uveomeningoencephalitic Syndrome*/chemically induced
Uveomeningoencephalitic Syndrome*/genetics
Humans ; Immune Checkpoint Inhibitors ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Evaluation of the Potential Impact of In Silico Humanization on V H H Dynamics.
Autorzy:
Martins C; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-75014 Paris, France.; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-97715 Saint Denis Messag, France.
Diharce J; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-75014 Paris, France.
Nadaradjane AA; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-97715 Saint Denis Messag, France.
de Brevern AG; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-75014 Paris, France.; Université Paris Cité and Université de la Réunion and Université des Antilles, INSERM, BIGR, DSIMB, F-97715 Saint Denis Messag, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 26; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Heavy Chains*/chemistry
Camelids, New World*
Humans ; Animals ; Antibodies ; Biotechnology
Czasopismo naukowe
Tytuł:
Sex differences in skeletal muscle size, function, and myosin heavy chain isoform expression during post-injury regeneration in mice.
Autorzy:
You JS; Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.; Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.; Nick J. Holonyak Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Barai P; Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Chen J; Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
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Źródło:
Physiological reports [Physiol Rep] 2023 Aug; Vol. 11 (16), pp. e15791.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Myosin Heavy Chains*/genetics
Sex Characteristics*
Female ; Male ; Animals ; Mice ; Muscle, Skeletal ; Muscle Fibers, Skeletal ; Fatigue ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł:
Characterization of the novel HLA-DRB3*03:49 allele by sequencing-based typing.
Autorzy:
Cargou M; CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.; University of Bordeaux, ImmunoConcEpT, CNRS UMR 5146, Bordeaux, France.
Andreani M; Laboratorio d'Immunogenetica dei Trapianti, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Troiano M; Laboratorio d'Immunogenetica dei Trapianti, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Ralazamahaleo M; CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.
Visentin J; CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.; University of Bordeaux, ImmunoConcEpT, CNRS UMR 5146, Bordeaux, France.
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Źródło:
HLA [HLA] 2021 May; Vol. 97 (5), pp. 477-478. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
HLA-DRB3 Chains*/genetics
Alleles ; Codon ; Exons/genetics ; HLA-DRB1 Chains/genetics ; Histocompatibility Testing ; Humans ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł:
Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses.
Autorzy:
Shrock EL; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Program in Biological and Biomedical Sciences, Harvard University, Boston, MA 02115, USA.
Timms RT; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.
Kula T; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Program in Biological and Biomedical Sciences, Harvard University, Boston, MA 02115, USA.
Mena EL; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.
West AP Jr; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Guo R; Division of Infectious Disease, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.
Lee IH; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
McKay LGA; National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston University, Boston, MA 02118, USA.
Bi C; Division of Allergy and Immunology, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA.
Leng Y; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.
Fujimura E; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.
Horns F; Department of Bioengineering, Department of Applied Physics, Chan Zuckerberg Biohub and Stanford University, Stanford, CA 94305, USA.
Li M; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.
Wesemann DR; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Division of Allergy and Immunology, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139 USA.
Griffiths A; National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston University, Boston, MA 02118, USA.
Gewurz BE; Division of Infectious Disease, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Graduate Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA.
Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Elledge SJ; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Apr 07; Vol. 380 (6640), pp. eadc9498. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Antibody Formation*
Immunodominant Epitopes*/chemistry
Immunodominant Epitopes*/genetics
Immunoglobulin Heavy Chains*/genetics
Immunoglobulin Heavy Chains*/immunology
Amino Acid Motifs*
Immunoglobulin Light Chains*/genetics
Immunoglobulin Light Chains*/immunology
Host-Pathogen Interactions*/genetics
Host-Pathogen Interactions*/immunology
Animals ; Humans ; Mice ; Germ Cells ; Epitope Mapping
Czasopismo naukowe
Tytuł:
Haplotype-dependent HLA-DRB1-DQB1 susceptibility to occult HBV infection in Xi'an Han population.
Autorzy:
Wang T; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Shen C; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Qi J; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Chen L; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Liu S; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Li H; Shaanxi Province Blood Center, Xi'an, People's Republic of China.
Pokaż więcej
Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2023 Apr; Vol. 11 (4), pp. e2102. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatitis B*/genetics
Hepatitis B, Chronic*
HLA-DRB1 Chains*/genetics
HLA-DQ beta-Chains*/genetics
Humans ; Case-Control Studies ; Gene Frequency ; Haplotypes ; Hepatitis B virus
Czasopismo naukowe

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