Kill and cure: genomic phylogeny and bioactivity of Burkholderia gladioli bacteria capable of pathogenic and beneficial lifestyles.
Autorzy :
Jones C; Present address: School of Applied Sciences, Faculty of Computing, Engineering and Science, University of South Wales, Pontypridd, CF37 4BD, UK.; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK. Webster G; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK. Mullins AJ; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK. Jenner M; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry CV4 7AL, UK.; Department of Chemistry and Warwick Integrative Synthetic Biology Centre, University of Warwick, CV4 7AL, UK. Bull MJ; Present address: Pathogen Genomics Unit, Public Health Wales Microbiology Cardiff, University Hospital of Wales, Cardiff, CF14 4XW, UK.; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK. Dashti Y; Present address: The Centre for Bacterial Cell Biology, Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK.; Department of Chemistry and Warwick Integrative Synthetic Biology Centre, University of Warwick, CV4 7AL, UK. Spilker T; Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA. Parkhill J; Present address: Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. Connor TR; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK. LiPuma JJ; Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA. ChallisGL; Department of Chemistry and Warwick Integrative Synthetic Biology Centre, University of Warwick, CV4 7AL, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry CV4 7AL, UK.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia. Mahenthiralingam E; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK.
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Źródło :
Microbial genomics [Microb Genom] 2021 Jan 18. Date of Electronic Publication: 2021 Jan 18.
Genomics-Driven Discovery of a Novel Glutarimide Antibiotic from Burkholderia gladioli Reveals an Unusual Polyketide Synthase Chain Release Mechanism.
Autorzy :
Nakou IT; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK. Jenner M; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, CV4 7AL, UK. Dashti Y; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Current Address: The Centre for Bacterial Cell Biology, Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK. Romero-Canelón I; Institute of Clinical Sciences, School of Pharmacy, University of Birmingham, Birmingham, B15 2TT, UK. Masschelein J; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Current Address: Laboratory for Biomolecular Discovery &, Engineering, VIB-KU Leuven Center for Microbiology, Department of Biology, KU Leuven, 3001, Leuven, Belgium. Mahenthiralingam E; Organisms and Environment Division, Cardiff School of Biosciences, Cardiff University, Cardiff, CF10 3AT, UK. ChallisGL; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, CV4 7AL, UK.; Department of Biochemistry and Molecular Biology, ARC Centre of Excellence for Innovations in Peptide and Protein Science, Monash University, Victoria, 3800, Australia.
Discovery and Biosynthesis of Bolagladins: Unusual Lipodepsipeptides from Burkholderia gladioli Clinical Isolates*.
Autorzy :
Dashti Y; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Current address: The Centre for Bacterial Cell Biology, Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK. Nakou IT; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK. Mullins AJ; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF103 AT, UK. Webster G; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF103 AT, UK. Jian X; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, CV4 7AL, UK. Mahenthiralingam E; Microbiomes, Microbes and Informatics Group, Organisms and Environment Division, School of Biosciences, Cardiff University, Cardiff, CF103 AT, UK. ChallisGL; Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.; Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry, CV4 7AL, UK.; Department of Biochemistry and Molecular Biology, ARC Centre of Excellence for Innovations in Peptide and Protein Science, Monash University, Clayton, VIC, 3800, Australia.
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