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Tytuł :
Quantitative characterization of the regulation of iron metabolism in glioblastoma stem-like cells using magnetophoresis.
Autorzy :
Park KJ; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
Kim J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
Testoff T; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
Adams J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
Poklar M; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
Zborowski M; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.
Venere M; Department of Radiation Oncology and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
Chalmers JJ; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2019 Jul; Vol. 116 (7), pp. 1644-1655. Date of Electronic Publication: 2019 Apr 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Magnetic Fields*
Microfluidic Analytical Techniques*
Brain Neoplasms/*metabolism
Glioblastoma/*metabolism
Iron/*metabolism
Neoplastic Stem Cells/*metabolism
Animals ; Brain Neoplasms/pathology ; Glioblastoma/pathology ; Humans ; Mice ; Neoplastic Stem Cells/pathology
Czasopismo naukowe
Tytuł :
Continuous, intrinsic magnetic depletion of erythrocytes from whole blood with a quadrupole magnet and annular flow channel; pilot scale study.
Autorzy :
Moore LR; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.
Mizutani D; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.; Department of Chemistry, Mie University, Japan.
Tanaka T; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.; Department of Chemistry, Mie University, Japan.
Buck A; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio.
Yazer M; Department of Pathology, University of Pittsburgh and The Institute for Transfusion Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Zborowski M; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.
Chalmers JJ; William G. Lowrie Department of Chemica, The Ohio State University, Columbus, Ohio.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2018 Jun; Vol. 115 (6), pp. 1521-1530. Date of Electronic Publication: 2018 Mar 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Erythrocytes*
Magnets*
Cell Separation/*methods
Cell Separation/instrumentation ; Humans
Czasopismo naukowe
Tytuł :
Correlation of simulation/finite element analysis to the separation of intrinsically magnetic spores and red blood cells using a microfluidic magnetic deposition system.
Autorzy :
Sun J; William G. Lowrie Department of Chemical and Biomolecular Engineering Director, Analytical Cytometry Shared Resource, The OSU Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
Moore L; Department of Biomedical Engineering Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Xue W; William G. Lowrie Department of Chemical and Biomolecular Engineering Director, Analytical Cytometry Shared Resource, The OSU Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
Kim J; William G. Lowrie Department of Chemical and Biomolecular Engineering Director, Analytical Cytometry Shared Resource, The OSU Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
Zborowski M; Department of Biomedical Engineering Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Chalmers JJ; William G. Lowrie Department of Chemical and Biomolecular Engineering Director, Analytical Cytometry Shared Resource, The OSU Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2018 May; Vol. 115 (5), pp. 1288-1300. Date of Electronic Publication: 2018 Feb 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Erythrocytes*
Bacillus/*isolation & purification
Cell Separation/*methods
Magnetics/*methods
Microfluidics/*methods
Spores, Bacterial/*isolation & purification
Cell Separation/instrumentation ; Finite Element Analysis ; Magnetics/instrumentation ; Microfluidics/instrumentation ; Models, Theoretical
Czasopismo naukowe
Tytuł :
Quantification of both the presence, and oxidation state, of Mn in Bacillus atrophaeus spores and its imparting of magnetic susceptibility to the spores.
Autorzy :
Sun J; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio 43210, USA.
Zborowski M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2011 May; Vol. 108 (5), pp. 1119-29. Date of Electronic Publication: 2011 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Magnetics*
Bacillus/*physiology
Spores, Bacterial/*growth & development
Mass Spectrometry/methods ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Quantification of non-specific binding of magnetic micro- and nanoparticles using cell tracking velocimetry: Implication for magnetic cell separation and detection.
Autorzy :
Chalmers JJ; William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Avenue, Columbus, OH 43210, USA. chalmers. />Xiong Y
Jin X
Shao M
Tong X
Farag S
Zborowski M
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2010 Apr 15; Vol. 105 (6), pp. 1078-93.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Magnetics*
Immunomagnetic Separation/*methods
Microfluidics/*methods
Nanoparticles/*chemistry
Cell Line ; Cells, Cultured ; Humans ; Kinetics ; Leukocytes, Mononuclear/cytology ; Microspheres
Czasopismo naukowe
Tytuł :
Physiological responses of CHO cells to repetitive hydrodynamic stress.
Autorzy :
Godoy-Silva R; Bioprocess R&D, Global Biologics, Pfizer, Inc., 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, USA.
Chalmers JJ
Casnocha SA
Bass LA
Ma N
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2009 Aug 15; Vol. 103 (6), pp. 1103-17.
Typ publikacji :
Journal Article
MeSH Terms :
Stress, Mechanical*
Stress, Physiological*
Eukaryotic Cells/*physiology
Animals ; Antibodies, Monoclonal/biosynthesis ; CHO Cells ; Cricetinae ; Cricetulus ; Glycosylation ; Recombinant Proteins/biosynthesis
Czasopismo naukowe
Tytuł :
Effects of energy dissipation rate on islets of Langerhans: implications for isolation and transplantation.
Autorzy :
Shenkman RM; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 W 19th Ave, Columbus, Ohio 43210, USA.
Godoy-Silva R
Papas KK
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2009 Jun 01; Vol. 103 (2), pp. 413-23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Stress, Mechanical*
Islets of Langerhans/*physiology
Animals ; Caspase 3/analysis ; Caspase 7/analysis ; Cell Membrane/physiology ; Insulin/metabolism ; Insulin Secretion ; Islets of Langerhans/chemistry ; Islets of Langerhans/cytology ; Islets of Langerhans Transplantation ; Oxygen Consumption ; Swine
Czasopismo naukowe
Tytuł :
Evaluation of the effect of chronic hydrodynamical stresses on cultures of suspensed CHO-6E6 cells.
Autorzy :
Godoy-Silva R; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 W 19th Ave., Columbus, Ohio 43210, USA.
Mollet M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2009 Mar 01; Vol. 102 (4), pp. 1119-30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques*
Stress, Physiological*
Animals ; CHO Cells ; Cell Proliferation ; Cell Survival ; Cricetinae ; Cricetulus
Czasopismo naukowe
Tytuł :
Optimization of an enrichment process for circulating tumor cells from the blood of head and neck cancer patients through depletion of normal cells.
Autorzy :
Yang L; Department of Chemical and Biomolecular Engineering, The Ohio State University, 125 Koffolt Laboratories, 140 West 19th Avenue, Columbus, Ohio 43210, USA.
Lang JC
Balasubramanian P
Jatana KR
Schuller D
Agrawal A
Zborowski M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2009 Feb 01; Vol. 102 (2), pp. 521-34.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neoplastic Cells, Circulating*
Head and Neck Neoplasms/*blood
Immunomagnetic Separation/*methods
Erythrocytes/chemistry ; Head and Neck Neoplasms/pathology ; Hemolysis ; Humans ; Leukocyte Common Antigens/analysis ; Staining and Labeling
Czasopismo naukowe
Tytuł :
An investigation of small-molecule surfactants to potentially replace pluronic F-68 for reducing bubble-associated cell damage.
Autorzy :
Hu W; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140W 19th Ave., Columbus, Ohio 43210, USA.
Rathman JJ
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2008 Sep 01; Vol. 101 (1), pp. 119-27.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Culture Techniques/*methods
Cell Survival/*physiology
Poloxamer/*administration & dosage
Poloxamer/*chemistry
Surface-Active Agents/*administration & dosage
Surface-Active Agents/*chemistry
Animals ; CHO Cells ; Cell Survival/drug effects ; Cricetinae ; Cricetulus ; Feasibility Studies ; Molecular Weight
Czasopismo naukowe
Tytuł :
Computer simulations of the energy dissipation rate in a fluorescence-activated cell sorter: Implications to cells.
Autorzy :
Mollet M; Department of Chemical and Biomolecular Engineering, The Ohio State University, 125 Koffolt Laboratories, 140 W 19th Ave, Columbus, Ohio 43210, USA.
Godoy-Silva R
Berdugo C
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2008 Jun 01; Vol. 100 (2), pp. 260-72.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Physiological Phenomena*
Computer-Aided Design*
Models, Biological*
Cell Separation/*instrumentation
Flow Cytometry/*instrumentation
Microfluidics/*instrumentation
Cell Separation/methods ; Computer Simulation ; Energy Transfer ; Equipment Design ; Equipment Failure Analysis ; Flow Cytometry/methods ; Microfluidics/methods
Czasopismo naukowe
Tytuł :
Acute hydrodynamic forces and apoptosis: a complex question.
Autorzy :
Mollet M; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 W 19th Ave., Columbus, Ohio 43210, USA.
Godoy-Silva R
Berdugo C
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2007 Nov 01; Vol. 98 (4), pp. 772-88.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Apoptosis/*physiology
Mechanotransduction, Cellular/*physiology
Microfluidics/*methods
Animals ; CHO Cells ; Computer Simulation ; Cricetinae ; Cricetulus ; Stress, Mechanical
Czasopismo naukowe
Tytuł :
Quantification of magnetic susceptibility in several strains of Bacillus spores: implications for separation and detection.
Autorzy :
Melnik K; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Ave, Columbus, Ohio 43210, USA.
Sun J
Fleischman A
Roy S
Zborowski M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2007 Sep 01; Vol. 98 (1), pp. 186-92.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Magnetics*
Bacillus/*isolation & purification
Bacillus/*radiation effects
Cell Separation/*methods
Bacillus/classification ; Bacillus/physiology ; Electrophoresis/methods ; Species Specificity ; Spores, Bacterial/classification ; Spores, Bacterial/isolation & purification ; Spores, Bacterial/physiology ; Spores, Bacterial/radiation effects
Czasopismo naukowe
Tytuł :
Blood progenitor cell separation from clinical leukapheresis product by magnetic nanoparticle binding and magnetophoresis.
Autorzy :
Jing Y; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, Ohio 44195, USA.
Moore LR
Williams PS
Chalmers JJ
Farag SS
Bolwell B
Zborowski M
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2007 Apr 15; Vol. 96 (6), pp. 1139-54.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Immunomagnetic Separation*/instrumentation
Immunomagnetic Separation*/methods
Hematopoietic Stem Cells/*cytology
Leukapheresis/*methods
Antigens, CD34/immunology ; Flow Cytometry ; Leukapheresis/instrumentation ; Magnetics ; Nanoparticles
Czasopismo naukowe
Tytuł :
Binding affinities/avidities of antibody-antigen interactions: quantification and scale-up implications.
Autorzy :
Zhang H; Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 W 19th Ave., Columbus, Ohio 43210, USA.
Williams PS
Zborowski M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2006 Dec 05; Vol. 95 (5), pp. 812-29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibody Affinity*
Models, Biological*
Antigen-Antibody Complex/*chemistry
Bacterial Proteins/*chemistry
Biotin/*analogs & derivatives
Cell Separation/*methods
Biotin/chemistry ; Flow Cytometry ; Immunologic Techniques ; Lymphocytes ; Magnetics
Czasopismo naukowe
Tytuł :
Comparison of two immunomagnetic separation technologies to deplete T cells from human blood samples.
Autorzy :
Lara O; Department of Chemical and Biomolecular Engineering, The Ohio State University, 120 Koffolt Laboratories, 140 W. 19th Avenue, Columbus, 43210, USA.
Tong X
Zborowski M
Farag SS
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2006 May 05; Vol. 94 (1), pp. 66-80.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Lymphocyte Depletion*
Blood Cells/*cytology
Hematopoietic Stem Cells/*cytology
Immunomagnetic Separation/*methods
Leukocytes, Mononuclear/*cytology
T-Lymphocytes/*cytology
Antigens, CD34/analysis ; CD3 Complex/analysis ; Cells, Cultured ; Humans ; Immunomagnetic Separation/instrumentation ; Isoantigens/analysis
Czasopismo naukowe
Tytuł :
Evaluation of a contraction flow field on hydrodynamic damage to entomopathogenic nematodes-A biological pest control agent.
Autorzy :
Fife JP; Department of Food, Agricultural and Biological Engineering, The Ohio State University, 1680 Madison Avenue, Wooster, Ohio 44691, USA. />Derksen RC
Ozkan HE
Grewal PS
Chalmers JJ
Krause CR
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2004 Apr 05; Vol. 86 (1), pp. 96-107.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study
MeSH Terms :
Models, Biological*
Mechanotransduction, Cellular/*physiology
Nematoda/*cytology
Nematoda/*physiology
Pest Control, Biological/*methods
Physical Stimulation/*methods
Rheology/*methods
Animals ; Computer Simulation ; Energy Transfer/physiology ; Nematoda/classification ; Pressure ; Shear Strength ; Species Specificity ; Stress, Mechanical ; Survival ; Survival Analysis
Czasopismo naukowe
Tytuł :
Characterization of antibody binding to three cancer-related antigens using flow cytometry and cell tracking velocimetry.
Autorzy :
Chosy EJ; Department of Chemical Engineering, Ohio State University, 125 Koffolt Laboratories, 140 West 19th Avenue, Columbus, Ohio 43210, USA.
Nakamura M
Melnik K
Comella K
Lasky LC
Zborowski M
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2003 May 05; Vol. 82 (3), pp. 340-51.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Validation Study
MeSH Terms :
Biomarkers, Tumor/*immunology
Breast Neoplasms/*classification
Breast Neoplasms/*immunology
Cell Separation/*methods
Flow Cytometry/*methods
Immunomagnetic Separation/*methods
Antigen-Antibody Reactions/immunology ; Antigens, Neoplasm/immunology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Movement ; Humans ; Rheology/methods ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Fabrication and use of a transient contractional flow device to quantify the sensitivity of mammalian and insect cells to hydrodynamic forces.
Autorzy :
Ma N; Department of Chemical Engineering, The Ohio State University, 140W 19th Ave., Columbus, Ohio 43210, USA.
Koelling KW
Chalmers JJ
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2002 Nov 20; Vol. 80 (4), pp. 428-37.
Typ publikacji :
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Models, Biological*
Breast Neoplasms/*physiopathology
CHO Cells/*physiology
Hybridomas/*physiology
Rheology/*instrumentation
Spodoptera/*physiology
Animals ; Cell Line ; Computer Simulation ; Cricetinae ; Equipment Design ; Humans ; Mice ; Miniaturization ; Rheology/methods ; Sensitivity and Specificity ; Shear Strength ; Stress, Mechanical
Czasopismo naukowe
Tytuł :
Mobility measurements of immunomagnetically labeled cells allow quantitation of secondary antibody binding amplification.
Autorzy :
McCloskey KE; Department of Biomedical Engineering/ND-20, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.
Comella K
Chalmers JJ
Margel S
Zborowski M
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2001 Dec 20; Vol. 75 (6), pp. 642-55.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Antigen-Antibody Reactions*
CD4 Antigens/immunology ; Fluorescent Antibody Technique ; Humans ; Immunoglobulin G/immunology ; Immunomagnetic Separation ; Lymphocyte Depletion ; Monocytes/immunology
Czasopismo naukowe

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