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Wyświetlanie 1-15 z 15
Tytuł:
Indoor-air purification by photoelectrochemical oxidation mitigates allergic airway responses to aerosolized cat dander in a murine model.
Autorzy:
Devadoss D; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA. .
Surbaugh K; Research and Development, Molekule Group, Inc., 3802 Spectrum Blvd, Tampa, FL, 33612, USA.
Manevski M; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Wickramaratne C; Research and Development, Molekule Group, Inc., 3802 Spectrum Blvd, Tampa, FL, 33612, USA.
Chaput D; Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, 33612, USA.
Chung A; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
de Leon F; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Chand HS; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Dhau JS; Research and Development, Molekule Group, Inc., 3802 Spectrum Blvd, Tampa, FL, 33612, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 06; Vol. 13 (1), pp. 10980. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypersensitivity*/metabolism
Asthma*
Air Pollution, Indoor*
Mice ; Animals ; Disease Models, Animal ; Dander/metabolism ; Proteomics ; Allergens
Czasopismo naukowe
Tytuł:
Distinct Exosomal miRNA Profiles from BALF and Lung Tissue of COPD and IPF Patients.
Autorzy:
Kaur G; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Maremanda KP; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Campos M; Division of Pulmonary, Allergy, Critical Care, University of Miami School of Medicine, Miami, FL 33136, USA.
Chand HS; Department of Immunology and Nanomedicine, Florida International University, Miami, FL 33199, USA.
Li F; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.
Hirani N; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.
Haseeb MA; Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203, USA.
Li D; Clinical and Translational Science Institute (CTSI), Public Health Sciences, University of Rochester Medical Center, Rochester, NY 14642, USA.
Rahman I; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 31; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*/genetics
Exosomes*/metabolism
Idiopathic Pulmonary Fibrosis*
MicroRNAs*/biosynthesis
MicroRNAs*/genetics
Pulmonary Disease, Chronic Obstructive*/genetics
Pulmonary Disease, Chronic Obstructive*/metabolism
Transcriptome*
Adult ; Aged ; Aged, 80 and over ; Bronchoalveolar Lavage Fluid ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
Differential plasma exosomal long non-coding RNAs expression profiles and their emerging role in E-cigarette users, cigarette, waterpipe, and dual smokers.
Autorzy:
Kaur G; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States of America.
Singh K; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States of America.
Maremanda KP; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States of America.
Li D; Department of Clinical & Translational Research, University of Rochester Medical Center, Rochester, NY, United States of America.
Chand HS; Department of Immunology and Nanomedicine, Florida International University, Miami, FL, United States of America.
Rahman I; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Dec 08; Vol. 15 (12), pp. e0243065. Date of Electronic Publication: 2020 Dec 08 (Print Publication: 2020).
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Exosomes/*genetics
Gene Expression Profiling/*methods
RNA, Long Noncoding/*genetics
Tobacco Smoking/*genetics
Vaping/*genetics
Water Pipe Smoking/*genetics
Case-Control Studies ; Female ; Gene Expression Regulation ; Gene Regulatory Networks ; Humans ; Male ; Oligonucleotide Array Sequence Analysis
Czasopismo naukowe
Tytuł:
TGF-β1 increases viral burden and promotes HIV-1 latency in primary differentiated human bronchial epithelial cells.
Autorzy:
Chinnapaiyan S; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Dutta RK; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Nair M; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Chand HS; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA.
Rahman I; University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, NY, 14642, USA.
Unwalla HJ; Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Aug 29; Vol. 9 (1), pp. 12552. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Differentiation*
Bronchi/*cytology
Epithelial Cells/*cytology
HIV-1/*physiology
Transforming Growth Factor beta1/*pharmacology
Viral Load/*drug effects
Virus Latency/*drug effects
Adaptor Proteins, Signal Transducing/genetics ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; HIV-1/drug effects ; Humans ; MicroRNAs/genetics ; Positive Regulatory Domain I-Binding Factor 1/genetics ; RNA, Messenger/genetics ; Signal Transduction/drug effects ; Transcription Factors/genetics ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł:
A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells.
Autorzy:
Hussain SS; Department of Immunology & Nano-Medicine, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL - 33199, USA.
George S; Department of Immunology & Nano-Medicine, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL - 33199, USA.
Singh S; Lovelace Respiratory Research Institute, Albuquerque, NM - 87108, USA.
Jayant R; Department of Immunology & Nano-Medicine, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL - 33199, USA.
Hu CA; Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM - 87131, USA.
Sopori M; Lovelace Respiratory Research Institute, Albuquerque, NM - 87108, USA.
Chand HS; Department of Immunology & Nano-Medicine, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL - 33199, USA. .
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Źródło:
Scientific reports [Sci Rep] 2018 Sep 14; Vol. 8 (1), pp. 13796. Date of Electronic Publication: 2018 Sep 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cigarette Smoking/*adverse effects
Proto-Oncogene Proteins c-bcl-2/*metabolism
Respiratory Mucosa/*metabolism
Animals ; Apoptosis ; Apoptosis Regulatory Proteins/metabolism ; Epithelial Cells/metabolism ; Genes, erbB-1 ; Goblet Cells/metabolism ; Humans ; Hyperplasia/pathology ; Lung/pathology ; MAP Kinase Signaling System ; Mice ; Mucin 5AC/metabolism ; Mucus/metabolism ; Peptide Fragments/metabolism ; Peptide Fragments/pharmacology ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins/pharmacology ; Proto-Oncogene Proteins c-bcl-2/drug effects ; Proto-Oncogene Proteins c-ets/metabolism ; Respiratory Mucosa/drug effects ; Signal Transduction ; Nicotiana/metabolism
Czasopismo naukowe
Tytuł:
Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity.
Autorzy:
Jang JH; a Department of Medicine , University of Pittsburgh , Pittsburgh , PA , USA.; b VA Pittsburgh Healthcare System , Pittsburgh , PA , USA.
Chand HS; c Department of Immunology , Herbert Wertheim College of Medicine, Florida International University Miami , Miami , FL , USA.
Bruse S; d Regeneron Genetics Center , Tarrytown , NY , USA.
Doyle-Eisele M; e COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Royer C; e COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
McDonald J; e COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Qualls C; f Biomedical Research Institute of New Mexico.
Klingelhutz AJ; g Department of Microbiology , University of Iowa, Roy J. and Lucille A. Carver College of Medicine , Iowa City , IA , USA.
Lin Y; e COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Mallampalli R; a Department of Medicine , University of Pittsburgh , Pittsburgh , PA , USA.; b VA Pittsburgh Healthcare System , Pittsburgh , PA , USA.
Tesfaigzi Y; e COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Nyunoya T; a Department of Medicine , University of Pittsburgh , Pittsburgh , PA , USA.; b VA Pittsburgh Healthcare System , Pittsburgh , PA , USA.
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Źródło:
COPD [COPD] 2017 Apr; Vol. 14 (2), pp. 228-237. Date of Electronic Publication: 2016 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/physiology
Cigarette Smoking/*metabolism
Connective Tissue Growth Factor/*metabolism
Epithelial Cells/*physiology
Pulmonary Disease, Chronic Obstructive/*physiopathology
Respiratory Mucosa/*metabolism
Aged ; Animals ; Biomarkers/metabolism ; Cell Line ; Cell Proliferation ; Connective Tissue Growth Factor/genetics ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Epithelial Cells/metabolism ; Female ; Humans ; Influenza A Virus, H3N2 Subtype ; Lung/metabolism ; Lung/pathology ; Macaca fascicularis ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Orthomyxoviridae Infections/metabolism ; Pulmonary Disease, Chronic Obstructive/metabolism ; RNA, Messenger/metabolism ; Severity of Illness Index ; Smoke/adverse effects ; Tobacco Products ; Up-Regulation ; beta-Galactosidase/metabolism
Czasopismo naukowe
Tytuł:
Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite.
Autorzy:
Jones JT; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Tassew DD; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Herrera LK; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Walton-Filipczak SR; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Montera MA; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Chand HS; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Delgado M; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Mebratu YA; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
Tesfaigzi Y; a COPD Program, Lovelace Respiratory Research Institute , Albuquerque , NM , USA.
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Źródło:
Inhalation toxicology [Inhal Toxicol] 2017 Feb; Vol. 29 (3), pp. 106-112. Date of Electronic Publication: 2017 Apr 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Allergens/*administration & dosage
Hypersensitivity/*immunology
Inflammation/*immunology
Pyroglyphidae/*immunology
Adaptive Immunity ; Allergens/immunology ; Animals ; Bronchoalveolar Lavage Fluid/immunology ; Epithelial Cells/pathology ; Hyperplasia/pathology ; Hypersensitivity/pathology ; Inflammation/pathology ; Lung/immunology ; Male ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways.
Autorzy:
Chand HS; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA. .; Present Address: Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA. .
Mebratu YA; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA.
Montera M; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA.
Tesfaigzi Y; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA.
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Źródło:
Respiratory research [Respir Res] 2016 Oct 20; Vol. 17 (1), pp. 132. Date of Electronic Publication: 2016 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Immunity, Mucosal*
Immunologic Memory*
Epithelial Cells/*immunology
Pneumonia/*immunology
Respiratory Mucosa/*immunology
T-Lymphocytes/*immunology
Animals ; Disease Models, Animal ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; ErbB Receptors/immunology ; ErbB Receptors/metabolism ; Forkhead Transcription Factors/deficiency ; Forkhead Transcription Factors/genetics ; Lipopolysaccharides ; Male ; Metaplasia ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Nude ; Mitogen-Activated Protein Kinase 1/immunology ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/immunology ; Mitogen-Activated Protein Kinase 3/metabolism ; Phosphorylation ; Pneumonia/chemically induced ; Pneumonia/metabolism ; Pneumonia/pathology ; Rats, Inbred F344 ; Respiratory Mucosa/metabolism ; Respiratory Mucosa/pathology ; Signal Transduction ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Time Factors ; Toll-Like Receptor 4/immunology ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł:
HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice.
Autorzy:
Singh SP; Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Chand HS; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Gundavarapu S; Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Saeed AI; Pulmonary and Critical Care Medicine, University of New Mexico, Albuquerque, New Mexico, United States of America.
Langley RJ; Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Tesfaigzi Y; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Mishra NC; Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
Sopori ML; Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Sep 11; Vol. 10 (9), pp. e0137757. Date of Electronic Publication: 2015 Sep 11 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bronchopulmonary Dysplasia/*etiology
Bronchopulmonary Dysplasia/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Maternal Exposure/*adverse effects
Smoking/*adverse effects
Alveolar Epithelial Cells/metabolism ; Angiogenesis Inhibitors/metabolism ; Animals ; Apoptosis ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bronchopulmonary Dysplasia/physiopathology ; Caspase 3/metabolism ; Disease Models, Animal ; Down-Regulation ; Female ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Keratins/metabolism ; Mecamylamine/pharmacology ; Mice ; NF-kappa B/metabolism ; Pregnancy ; Respiratory Mucosa/metabolism
Czasopismo naukowe
Tytuł:
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues.
Autorzy:
Kempaiah P; Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. />Chand HS
Kisiel W
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Źródło:
Molecular cancer [Mol Cancer] 2007 Mar 12; Vol. 6, pp. 20. Date of Electronic Publication: 2007 Mar 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
RNA Splicing*
Glycoproteins/*genetics
Neoplasm Proteins/*genetics
5' Untranslated Regions/genetics ; Cell Line, Tumor/drug effects ; Cell Line, Tumor/metabolism ; Dactinomycin/pharmacology ; Exons/genetics ; Glycoproteins/biosynthesis ; Glycoproteins/chemistry ; Half-Life ; Humans ; Introns/genetics ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/chemistry ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Nucleic Acid Synthesis Inhibitors/pharmacology ; Organ Specificity ; Poly A/genetics ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Transcription, Genetic/drug effects ; Up-Regulation ; Viscera/metabolism
Czasopismo naukowe
    Wyświetlanie 1-15 z 15

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