Autor: "Chang TK" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: CYP1B1 expression in rat testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists.
Autorzy:: Deb S; Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
Kawai M
Chang TK
Bandiera SM; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2010 Jul; Vol. 40 (7), pp. 447-57.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*metabolism
Gene Expression Regulation, Enzymologic/*drug effects
Leydig Cells/*metabolism
Receptors, Aryl Hydrocarbon/*agonists
Animals ; Benzo(a)pyrene/pharmacology ; Cell Line ; Cytochrome P-450 CYP1B1 ; Dose-Response Relationship, Drug ; Gene Expression Regulation, Enzymologic/physiology ; Immunoblotting ; Male ; Methylcholanthrene/pharmacology ; Mice ; Polychlorinated Dibenzodioxins/pharmacology ; Rats ; Rats, Sprague-Dawley

Czasopismo naukowe

Skocz do pozycji: 2.

Tytuł:: Inhibition of procarcinogen-bioactivating human CYP1A1, CYP1A2 and CYP1B1 enzymes by melatonin.
Autorzy:: Chang TK; Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada.
Chen J
Yang G
Yeung EY; Pokaż więcej
Źródło:: Journal of pineal research [J Pineal Res] 2010 Jan; Vol. 48 (1), pp. 55-64. Date of Electronic Publication: 2009 Nov 16.
Typ publikacji:: Journal Article
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 CYP1A2/*metabolism
Melatonin/*pharmacology
Aryl Hydrocarbon Hydroxylases/genetics ; Benzopyrenes/metabolism ; Cell Line ; Cells, Cultured ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A2/genetics ; Cytochrome P-450 CYP1B1 ; Cytochrome P-450 CYP2A6 ; Enzyme Activation/drug effects ; Enzyme Inhibitors/pharmacology ; Humans ; Microsomes, Liver/metabolism ; Oxazines/metabolism ; Plasmids ; Polymerase Chain Reaction

Czasopismo naukowe

Skocz do pozycji: 3.

Tytuł:: Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.
Autorzy:: Numa AM; Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC V6T 1Z3, Canada.
Abbott FS
Chang TK; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2007 Sep; Vol. 85 (9), pp. 848-55.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ginkgo biloba*
Anticonvulsants/*metabolism
Aryl Hydrocarbon Hydroxylases/*genetics
Microsomes, Liver/*metabolism
Valproic Acid/*metabolism
Adult ; Aged ; Aryl Hydrocarbon Hydroxylases/metabolism ; Catalysis ; Cytochrome P-450 CYP2A6 ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP2C9 ; DNA, Complementary/genetics ; Female ; Genotype ; Humans ; In Vitro Techniques ; Male ; Middle Aged ; Mixed Function Oxygenases/genetics ; Mixed Function Oxygenases/metabolism ; Oxidation-Reduction ; Oxidoreductases, N-Demethylating/genetics ; Oxidoreductases, N-Demethylating/metabolism ; Plant Extracts/pharmacology

Czasopismo naukowe

Skocz do pozycji: 4.

Tytuł:: Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes.
Autorzy:: Ho PC; 1Faculty of Pharmaceutical Sciences, The University of British Columbia, British Columbia, Canada.
Abbott FS
Zanger UM
Chang TK; Pokaż więcej
Źródło:: The pharmacogenomics journal [Pharmacogenomics J] 2003; Vol. 3 (6), pp. 335-42.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*genetics
Aryl Hydrocarbon Hydroxylases/*metabolism
Microsomes, Liver/*drug effects
Valproic Acid/*metabolism
Valproic Acid/*toxicity
Analysis of Variance ; Animals ; Cytochrome P-450 CYP2C9 ; Genotype ; Humans ; Insecta ; Microsomes, Liver/enzymology

Czasopismo naukowe

Skocz do pozycji: 5.

Tytuł:: Effect of exogenous growth hormone on somatic growth, gonadal development, and hepatic CYP2C11 and CYP2C12 expression in prepubertal intact male rats.
Autorzy:: Kawai M; Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada.
Bandiera SM
Chang TK
Bellward GD; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2001 Apr; Vol. 79 (4), pp. 352-61.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Aryl Hydrocarbon Hydroxylases*
Steroid 16-alpha-Hydroxylase*
Cytochrome P-450 Enzyme System/*biosynthesis
Growth Hormone/*pharmacology
Sexual Maturation/*drug effects
Steroid Hydroxylases/*biosynthesis
Testis/*drug effects
Animals ; Body Weight/drug effects ; Body Weight/physiology ; Cytochrome P450 Family 2 ; Female ; Male ; Microsomes, Liver/drug effects ; Microsomes, Liver/metabolism ; Organ Size/drug effects ; Organ Size/physiology ; RNA, Messenger/biosynthesis ; Rats ; Rats, Sprague-Dawley ; Sexual Maturation/physiology ; Testis/metabolism

Czasopismo naukowe

Informacja