- Tytuł:
- Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.
- Autorzy:
- Źródło:
- Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2007 Sep; Vol. 85 (9), pp. 848-55.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Ginkgo biloba*
Anticonvulsants/*metabolism
Aryl Hydrocarbon Hydroxylases/*geneticsMicrosomes, Liver /*metabolism
Valproic Acid/*metabolism
Adult ; Aged ; Aryl Hydrocarbon Hydroxylases/metabolism ; Catalysis ; Cytochrome P-450 CYP2A6 ; Cytochrome P-450 CYP2B6 ; Cytochrome P-450 CYP2C9 ; DNA, Complementary/genetics ; Female ; Genotype ; Humans ; In Vitro Techniques ; Male ; Middle Aged ; Mixed Function Oxygenases/genetics ; Mixed Function Oxygenases/metabolism ; Oxidation-Reduction ; Oxidoreductases, N-Demethylating/genetics ; Oxidoreductases, N-Demethylating/metabolism ; Plant Extracts/pharmacology
Czasopismo naukowe