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Tytuł:
Cognitive impairment is associated with mitochondrial dysfunction in peripheral blood mononuclear cells of elderly population.
Autorzy:
Apaijai N; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Sriwichaiin S; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Phrommintikul A; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.; Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Jaiwongkam T; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Kerdphoo S; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chansirikarnjana S; Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Thongmung N; Research Center Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Mahantassanapong U; Medical and Health Division, Electricity Generating Authority of Thailand, EGAT 53 Moo 2 Charansanitwong Road, Bangkruai, 11130, Nonthaburi, Thailand.
Vathesatogkit P; Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Kitiyakara C; Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Sritara P; Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Chattipakorn N; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.; Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chattipakorn SC; Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 08; Vol. 10 (1), pp. 21400. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers/*blood
Cognitive Dysfunction/*metabolism
Cognitive Dysfunction/*psychology
Leukocytes, Mononuclear/*metabolism
Mitochondria/*metabolism
Adenosine Triphosphate/metabolism ; Aged ; Aged, 80 and over ; Disease Progression ; Female ; Glomerular Filtration Rate ; Humans ; Lipoproteins, LDL/blood ; Male ; Oxidative Stress ; Thailand
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of Sirtuin 3 and Maintenance of Mitochondrial Integrity by N -Acetylcysteine Protects Against Bisphenol A-Induced Kidney and Liver Toxicity in Rats.
Autorzy:
Peerapanyasut W; Renal Physiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. .
Kobroob A; Division of Physiology, School of Medical Sciences, University of Phayao, Phayao 56000, Thailand. .
Palee S; Cardiac Electrophysiology Research and Training Center, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. .
Chattipakorn N; Cardiac Electrophysiology Research and Training Center, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. .
Wongmekiat O; Renal Physiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jan 11; Vol. 20 (2). Date of Electronic Publication: 2019 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcysteine/*administration & dosage
Benzhydryl Compounds/*toxicity
Chemical and Drug Induced Liver Injury/*prevention & control
Kidney Diseases/*prevention & control
Mitochondria/*metabolism
Phenols/*toxicity
Sirtuins/*metabolism
Acetylcysteine/pharmacology ; Animals ; Apoptosis/drug effects ; Chemical and Drug Induced Liver Injury/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Kidney Diseases/chemically induced ; Kidney Diseases/metabolism ; Male ; Mitochondria/drug effects ; Mitochondrial Dynamics/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impaired mitochondria and intracellular calcium transients in the salivary glands of obese rats.
Autorzy:
Ittichaicharoen J; a Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Apaijai N; b Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Tanajak P; c Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Department of Physiology, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Sa-Nguanmoo P; c Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Department of Physiology, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chattipakorn N; c Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Department of Physiology, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
Chattipakorn SC; a Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand.
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Źródło:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2017 Apr; Vol. 42 (4), pp. 420-429. Date of Electronic Publication: 2016 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling*
Insulin Resistance*
Mitochondria/*metabolism
Obesity/*physiopathology
Prediabetic State/*physiopathology
Salivary Glands/*metabolism
Sialadenitis/*etiology
Acinar Cells/immunology ; Acinar Cells/metabolism ; Acinar Cells/pathology ; Acinar Cells/ultrastructure ; Animals ; Apoptosis ; Biomarkers/metabolism ; Diet, High-Fat/adverse effects ; Fibrosis ; Male ; Membrane Potential, Mitochondrial ; Microscopy, Electron, Transmission ; Mitochondria/immunology ; Mitochondria/pathology ; Mitochondria/ultrastructure ; Mitochondrial Swelling ; Obesity/immunology ; Obesity/metabolism ; Obesity/pathology ; Oxidative Stress ; Prediabetic State/immunology ; Prediabetic State/metabolism ; Prediabetic State/pathology ; Random Allocation ; Rats, Wistar ; Reactive Oxygen Species/metabolism ; Salivary Glands/immunology ; Salivary Glands/pathology ; Salivation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protocatechuic acid protects brain mitochondrial function in streptozotocin-induced diabetic rats.
Autorzy:
Semaming Y; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; b Veterinary Technology Program, Faculty of Technology, Udon Thani Rajabhat University, Udon Thani 41000 Thailand.
Sripetchwandee J; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; c Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Sa-Nguanmoo P; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; c Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Pintana H; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; c Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Pannangpetch P; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; d Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Chattipakorn N; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; c Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Chattipakorn SC; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; e Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
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Źródło:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2015 Oct; Vol. 40 (10), pp. 1078-81. Date of Electronic Publication: 2015 Jun 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Experimental*
Brain/*drug effects
Hydroxybenzoates/*pharmacology
Mitochondria/*drug effects
Animals ; Anticarcinogenic Agents/pharmacology ; Disease Models, Animal ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Chronic testosterone replacement exerts cardioprotection against cardiac ischemia-reperfusion injury by attenuating mitochondrial dysfunction in testosterone-deprived rats.
Autorzy:
Pongkan W; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Cardiac Electrophysiology unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.
Chattipakorn SC; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.
Chattipakorn N; Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Cardiac Electrophysiology unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, Thailand.
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Źródło:
PloS one [PLoS One] 2015 Mar 30; Vol. 10 (3), pp. e0122503. Date of Electronic Publication: 2015 Mar 30 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiotonic Agents/*pharmacology
Heart/*drug effects
Mitochondria/*drug effects
Myocardial Reperfusion Injury/*drug therapy
Reperfusion Injury/*drug therapy
Testosterone/*pharmacology
Ventricular Function, Left/*drug effects
Animals ; Arrhythmias, Cardiac/drug therapy ; Heart Rate/drug effects ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Garlic extract attenuates brain mitochondrial dysfunction and cognitive deficit in obese-insulin resistant rats.
Autorzy:
Pintana H; a Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sripetchwandee J
Supakul L
Apaijai N
Chattipakorn N
Chattipakorn S
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Źródło:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2014 Dec; Vol. 39 (12), pp. 1373-9. Date of Electronic Publication: 2014 Oct 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Garlic*
Insulin Resistance*
Phytotherapy*
Cognition Disorders/*etiology
Cognition Disorders/*prevention & control
Mitochondria/*drug effects
Obesity/*complications
Obesity/*metabolism
Plant Extracts/*therapeutic use
Animals ; Brain/metabolism ; Brain/ultrastructure ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.
Autorzy:
Pipatpiboon N; Neurophysiology Unit, Faculty of Medicine, Cardiac Electrophysiology Research and Training Center, Chiang Mai University, Chiang Mai, 50200, Thailand.
Pintana H
Pratchayasakul W
Chattipakorn N
Chattipakorn SC
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2013 Mar; Vol. 37 (5), pp. 839-49. Date of Electronic Publication: 2012 Dec 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adamantane/*analogs & derivatives
Brain/*physiology
Cognition/*drug effects
Diet, High-Fat/*adverse effects
Dipeptidyl-Peptidase IV Inhibitors/*pharmacology
Mitochondria/*drug effects
Nitriles/*pharmacology
Pyrrolidines/*pharmacology
Receptor, Insulin/*metabolism
Adamantane/pharmacology ; Animals ; Brain/drug effects ; Brain/metabolism ; Gene Expression ; Glucagon-Like Peptide 1/genetics ; Glucagon-Like Peptide 1/metabolism ; Insulin Receptor Substrate Proteins/metabolism ; Insulin Resistance ; Long-Term Synaptic Depression/drug effects ; Male ; Maze Learning/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Memory/drug effects ; Mitochondria/physiology ; Neurons/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Wistar ; Vildagliptin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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