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Wyszukujesz frazę ""Chelating Agents"" wg kryterium: Temat


Tytuł :
Using Nanochelating Technology for Biofortification and Yield Increase in Rice.
Autorzy :
Fakharzadeh S; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran.
Hafizi M; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran.; Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Baghaei MA; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran.; Department of Agronomy, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
Etesami M; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran.
Khayamzadeh M; Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kalanaky S; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran. .
Akbari ME; Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
Nazaran MH; Department of Research and Development, Sodour Ahrar Shargh Company, Tehran, Iran. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 09; Vol. 10 (1), pp. 4351. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biofortification*
Chelating Agents*/chemical synthesis
Chelating Agents*/chemistry
Chelating Agents*/pharmacology
Crop Production*
Nanotechnology*/methods
Oryza*/chemistry
Oryza*/drug effects
Oryza*/growth & development
Chemical Phenomena ; Fertilizers ; Iron Chelating Agents/chemistry ; Micronutrients/analysis ; Micronutrients/chemistry ; Nanoparticles/chemistry ; Nanoparticles/ultrastructure
Czasopismo naukowe
Tytuł :
The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity.
Autorzy :
Park KC; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building, University of Sydney, Sydney 2006, New South Wales, Australia.
Dharmasivam M; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building, University of Sydney, Sydney 2006, New South Wales, Australia.; Centre for Cancer Cell Biology and Drug Discovery, Griffith Institute of Drug Discovery, Griffith University, Nathan, Brisbane 4111, Queensland, Australia.
Richardson DR; Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building, University of Sydney, Sydney 2006, New South Wales, Australia.; Centre for Cancer Cell Biology and Drug Discovery, Griffith Institute of Drug Discovery, Griffith University, Nathan, Brisbane 4111, Queensland, Australia.; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 16; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Iron*
Zinc*
Antineoplastic Agents/*therapeutic use
Chelating Agents/*therapeutic use
Neoplasm Proteins/*physiology
Peptide Hydrolases/*physiology
Protease Inhibitors/*therapeutic use
Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Chelating Agents/pharmacology ; Disease Progression ; Drug Design ; Drug Screening Assays, Antitumor ; Extracellular Fluid/enzymology ; Extracellular Vesicles/enzymology ; Humans ; Hydroxamic Acids/pharmacology ; Hydroxamic Acids/therapeutic use ; Iron Chelating Agents/pharmacology ; Iron Chelating Agents/therapeutic use ; Kallikreins/antagonists & inhibitors ; Kallikreins/physiology ; Matrix Metalloproteinases/physiology ; Molecular Targeted Therapy ; Neoplasm Proteins/antagonists & inhibitors ; Oxaprozin/pharmacology ; Oxaprozin/therapeutic use ; Phenylalanine/analogs & derivatives ; Phenylalanine/pharmacology ; Phenylalanine/therapeutic use ; Protease Inhibitors/pharmacology ; Protein Kinases/physiology ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Thiophenes/pharmacology ; Thiophenes/therapeutic use ; Thiosemicarbazones/pharmacology ; Thiosemicarbazones/therapeutic use
Czasopismo naukowe
Tytuł :
Adsorptivity of cationic cellulose nanocrystals for phosphate and its application in hyperphosphatemia therapy.
Autorzy :
Zhang Q; Blood Purification Center, Beijing Zhongguancun Hospital, Beijing 100080, China. Electronic address: .
Wang M; Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes, National Laboratory of Mineral Materials, School of Materials Science and Technology, China University of Geosciences (Beijing), Beijing 100083, China; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for NanoScience and Technology, No. 11 Zhongguancun Beiyitiao, Beijing 100190, China. Electronic address: .
Mu G; Blood Purification Center, Beijing Zhongguancun Hospital, Beijing 100080, China. Electronic address: .
Ren H; School of Printing and Packaging Engineering, Beijing Institute of Graphic Communication, Beijing 102600, China. Electronic address: .
He C; Blood Purification Center, Beijing Zhongguancun Hospital, Beijing 100080, China. Electronic address: .
Xie Q; Division of Nephrology, Peking University Third Hospital, Beijing 100191, China. Electronic address: .
Liu Q; School of Printing and Packaging Engineering, Beijing Institute of Graphic Communication, Beijing 102600, China. Electronic address: .
Wang J; School of Printing and Packaging Engineering, Beijing Institute of Graphic Communication, Beijing 102600, China. Electronic address: .
Cha R; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for NanoScience and Technology, No. 11 Zhongguancun Beiyitiao, Beijing 100190, China; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, National Institutes for Food and Drug Control, 2 Tiantan Xi Li, Beijing 100050, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Mar 01; Vol. 255, pp. 117335. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cellulose/*pharmacology
Chelating Agents/*pharmacology
Hyperphosphatemia/*drug therapy
Kidney/*drug effects
Nanoparticles/*chemistry
Phosphates/*isolation & purification
Adenine/administration & dosage ; Adsorption ; Animals ; Biomarkers/blood ; Cellulose/chemistry ; Cellulose/metabolism ; Chelating Agents/metabolism ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Disease Models, Animal ; Feces/chemistry ; Humans ; Hyperphosphatemia/chemically induced ; Hyperphosphatemia/metabolism ; Hyperphosphatemia/pathology ; Intestine, Small/drug effects ; Intestine, Small/metabolism ; Kidney/metabolism ; Liver/drug effects ; Liver/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Nanoparticles/administration & dosage ; Phosphates/metabolism ; Treatment Outcome ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
State-of-the-Art Management of Hyperphosphatemia in Patients With CKD: An NKF-KDOQI Controversies Perspective.
Autorzy :
Scialla JJ; Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA. Electronic address: .
Kendrick J; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO.
Uribarri J; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Kovesdy CP; Department of Medicine, University of Tennessee Health Science Center and Memphis Veterans Affairs Medical Center, Memphis, TN.
Gutiérrez OM; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
Jimenez EY; Department of Pediatrics, University of New Mexico, Albuquerque, New Mexico; Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico; Nutrition Research Network, Academy of Nutrition and Dietetics, Chicago, IL.
Kramer HJ; Department of Medicine, Loyola University Chicago, Maywood, IL; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL.
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Źródło :
American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2021 Jan; Vol. 77 (1), pp. 132-141. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chelating Agents*/pharmacology
Chelating Agents*/therapeutic use
Hyperphosphatemia*/blood
Hyperphosphatemia*/etiology
Hyperphosphatemia*/therapy
Patient Care Management*/methods
Patient Care Management*/standards
Patient Care Management*/trends
Renal Insufficiency, Chronic*/complications
Renal Insufficiency, Chronic*/metabolism
Renal Insufficiency, Chronic*/therapy
Calcium/metabolism ; Clinical Trials as Topic ; Humans ; Phosphates/metabolism ; Renal Dialysis/adverse effects ; Renal Dialysis/methods
Czasopismo naukowe
Tytuł :
Characterization of Thorium-Pyrazinoic acid complexation and its decorporation efficacy in human cells and blood.
Autorzy :
Dumpala RMR; Radiochemistry Division, Bhabha Atomic Research Centre, Mumbai, 400094, India. Electronic address: .
Das SK; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
Ali M; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
Boda A; Chemical Engineering Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
Kumar P; Fuel Chemistry Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
Rawat N; Radiochemistry Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
Kumar A; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, 400094, India. Electronic address: .
Ali SM; Chemical Engineering Division, Bhabha Atomic Research Centre, Mumbai, 400094, India.
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Źródło :
Chemosphere [Chemosphere] 2021 May; Vol. 271, pp. 129547. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Chelating Agents*
Thorium*
Animals ; Humans ; Pyrazinamide/analogs & derivatives ; Thermodynamics
Czasopismo naukowe
Tytuł :
A 15-years follow-up of deferasirox in beta-thalassaemia major patients with iron overload.
Autorzy :
Wei Z; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yang G; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Huang Y; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Peng P; Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Long L; Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Long Y; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Huang X; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhou X; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Lai Y; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Liu R; Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
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Źródło :
British journal of haematology [Br J Haematol] 2020 Nov; Vol. 191 (3), pp. e81-e83. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Deferasirox/*therapeutic use
Iron Chelating Agents/*therapeutic use
Iron Overload/*drug therapy
Iron Overload/*etiology
beta-Thalassemia/*complications
Biomarkers ; Deferasirox/administration & dosage ; Deferasirox/adverse effects ; Follow-Up Studies ; Humans ; Iron Chelating Agents/administration & dosage ; Iron Chelating Agents/adverse effects ; Iron Overload/complications ; Iron Overload/diagnosis ; Prognosis ; Treatment Outcome
Raport
Tytuł :
Self-assembling nitrilotriacetic acid nanofibers for tracking and enriching His-tagged proteins in living cells.
Autorzy :
Zhang LS; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, NanKai University, Tianjin 300350, China. .
Yin YL
Wang L
Xia Y
Ryu S
Xi Z
Li LY
Zhang ZS
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Źródło :
Journal of materials chemistry. B [J Mater Chem B] 2021 Jan 07; Vol. 9 (1), pp. 80-84. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanofibers*/analysis
Chelating Agents/*metabolism
Cytoplasm/*metabolism
Histidine/*metabolism
Nitrilotriacetic Acid/*metabolism
Oligopeptides/*metabolism
Chelating Agents/analysis ; Cytoplasm/chemistry ; Fluorescent Dyes/analysis ; Fluorescent Dyes/metabolism ; Histidine/analysis ; Humans ; MCF-7 Cells ; Nitrilotriacetic Acid/analysis ; Oligopeptides/analysis
Czasopismo naukowe
Tytuł :
Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine.
Autorzy :
Komoto K; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Nomoto T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
El Muttaqien S; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.; Center for Pharmaceutical and Medical Technology, Agency for the Assessment and Application of Technology (BPPT), LAPTIAB I, PUSPIPTEK, Serpong, Indonesia.
Takemoto H; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Matsui M; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Miura Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
Nishiyama N; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.; Innovation Center of Nanomedicine (iCONM), Kawasaki Institute of Industrial Promotion, Kawasaki, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Jan; Vol. 112 (1), pp. 410-421. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Deferoxamine/*pharmacology
Drug Carriers/*pharmacology
Iron Chelating Agents/*pharmacology
Animals ; Cell Line, Tumor ; Deferoxamine/chemistry ; Drug Carriers/chemistry ; Iron Chelating Agents/chemistry ; Mice ; Mice, Inbred BALB C ; Neoplasms, Experimental/drug therapy ; Peptides/chemistry ; Peptides/pharmacology ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacology
Czasopismo naukowe
Tytuł :
Lead removal by ThioOctolig.
Autorzy :
Martin DF; Department of Chemistry, University of South Florida, Tampa, Florida, USA.
Bisht KS; Department of Chemistry, University of South Florida, Tampa, Florida, USA.
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Źródło :
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering [J Environ Sci Health A Tox Hazard Subst Environ Eng] 2021; Vol. 56 (2), pp. 157-160. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
MeSH Terms :
Chelating Agents/*chemistry
Lead/*analysis
Polyethylenes/*chemistry
Silica Gel/*chemistry
Thioacetamide/*chemistry
Water Pollutants, Chemical/*analysis
Adsorption ; Chelating Agents/chemical synthesis ; Drinking Water/analysis ; Drinking Water/standards ; Models, Theoretical ; Surface Properties ; Water Purification/methods
Czasopismo naukowe
Tytuł :
Interaction between Calcium Chelators and the Activity of P2X7 Receptors in Mouse Motor Synapses.
Autorzy :
Miteva A; Department of Human & Animal Physiology, Lomonosov Moscow State University, Leninskie Gory 1/12, Moscow 119991, Russia.
Gaydukov A; Department of Human & Animal Physiology, Lomonosov Moscow State University, Leninskie Gory 1/12, Moscow 119991, Russia.
Balezina O; Department of Human & Animal Physiology, Lomonosov Moscow State University, Leninskie Gory 1/12, Moscow 119991, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 16; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Chelating Agents/*pharmacology
Receptors, Purinergic P2X7/*drug effects
Receptors, Purinergic P2X7/*metabolism
Synapses/*drug effects
Synapses/*metabolism
Acetylcholine/pharmacology ; Animals ; Calcium/metabolism ; Calcium Channel Blockers ; Calcium Channels, L-Type/metabolism ; Chelating Agents ; Connexins/genetics ; Egtazic Acid/analogs & derivatives ; Egtazic Acid/antagonists & inhibitors ; Excitatory Postsynaptic Potentials ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Neuromuscular Junction/metabolism ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Multilayer Microcapsules with Shell-Chelated Zr for PET Imaging and Controlled Delivery.
Autorzy :
Kozlovskaya V; Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.; Center for Nanomaterials and Biointegration, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Alford A; Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Dolmat M; Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Ducharme M; Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Caviedes R; Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Radford L; Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Lapi SE; Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
Kharlampieva E; Department of Chemistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.; Center for Nanomaterials and Biointegration, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2020 Dec 23; Vol. 12 (51), pp. 56792-56804. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Chelating Agents/*chemistry
Contrast Media/*chemistry
Doxorubicin/*therapeutic use
Drug Carriers/*chemistry
Neoplasms/*drug therapy
Acrylic Resins/chemistry ; Acrylic Resins/pharmacokinetics ; Animals ; Capsules ; Chelating Agents/pharmacokinetics ; Contrast Media/pharmacokinetics ; Deferoxamine/chemistry ; Deferoxamine/pharmacokinetics ; Drug Carriers/pharmacokinetics ; Female ; Mice, Inbred BALB C ; Positron-Emission Tomography/methods ; Povidone/chemistry ; Povidone/pharmacokinetics ; Precision Medicine/methods ; Radioisotopes/chemistry ; Tannins/chemistry ; Tannins/pharmacokinetics ; Ultrasonic Waves ; Zirconium/chemistry
Czasopismo naukowe
Tytuł :
Hydroxypyridinone-Based Iron Chelators with Broad-Ranging Biological Activities.
Autorzy :
Jiang X; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, P.R. China.
Zhou T; School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, P.R. China.
Bai R; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, P.R. China.
Xie Y; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, P.R. China.; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, P.R. China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Dec 10; Vol. 63 (23), pp. 14470-14501. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Iron Chelating Agents/*pharmacology
Pyridones/*pharmacology
Animals ; Humans ; Iron Chelating Agents/therapeutic use ; Iron Overload/drug therapy ; Pyridones/therapeutic use
Czasopismo naukowe
Tytuł :
Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity.
Autorzy :
Yamada Y; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Takashima H; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Walmsley DL; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Ushiyama F; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Matsuda Y; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Kanazawa H; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Yamaguchi-Sasaki T; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Tanaka-Yamamoto N; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Yamagishi J; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Kurimoto-Tsuruta R; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Ogata Y; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Ohtake N; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Angove H; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Baker L; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Harris R; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Macias A; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Robertson A; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Surgenor A; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
Watanabe H; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Nakano K; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Mima M; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Iwamoto K; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Okada A; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Takata I; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Hitaka K; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Tanaka A; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Fujita K; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Sugiyama H; Taisho Pharmaceutical Co., Ltd., Saitama 331-9530, Japan.
Hubbard RE; Vernalis (R&D) Ltd., Granta Park, Cambridge CB21 6GB, U.K.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Dec 10; Vol. 63 (23), pp. 14805-14820. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Amidohydrolases/*antagonists & inhibitors
Anti-Bacterial Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Chelating Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Anilides/pharmacology ; Anti-Bacterial Agents/chemical synthesis ; Chelating Agents/chemical synthesis ; Drug Discovery ; Enzyme Inhibitors/chemical synthesis ; Escherichia coli/drug effects ; Escherichia coli/enzymology ; Imidazoles/pharmacology ; Microbial Sensitivity Tests ; Molecular Structure ; Piperidines/pharmacology ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/enzymology ; Structure-Activity Relationship ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
Design of a multivalent bifunctional chelator for diagnostic Cu PET imaging in Alzheimer's disease.
Autorzy :
Cho HJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Huynh TT; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108.; Department of Chemistry, Washington University, St. Louis, MO 63130.
Rogers BE; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63108.
Mirica LM; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801; .; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 08; Vol. 117 (49), pp. 30928-30933. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Positron-Emission Tomography*
Alzheimer Disease/*diagnosis
Alzheimer Disease/*diagnostic imaging
Chelating Agents/*chemistry
Copper Radioisotopes/*chemistry
Animals ; Autoradiography ; Chelating Agents/chemical synthesis ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
The iron chelating activity of Gundelia tournefortii in iron overloaded experimental rats.
Autorzy :
Mansi K; Department of Medical Laboratory Science, Faculty of Science, Al Al-Bayt University, P.O. Box 130040, Mafraq, 25113, Jordan. Electronic address: .
Tabaza Y; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, 11942, Jordan. Electronic address: .
Aburjai T; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, 11942, Jordan. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Dec 05; Vol. 263, pp. 113114. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Asteraceae*
Iron Chelating Agents/*therapeutic use
Iron Overload/*blood
Iron Overload/*drug therapy
Plant Extracts/*therapeutic use
Animals ; Iron/blood ; Iron Chelating Agents/isolation & purification ; Male ; Plant Components, Aerial ; Plant Extracts/isolation & purification ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Comparative efficacy of Nano and Bulk Monoisoamyl DMSA against arsenic-induced neurotoxicity in rats.
Autorzy :
Naqvi S; National Institute of Pharmaceutical Education and Research (NIPER-Raebareli), Bijnor-Sisendi Road, CRPF Base Camp, P.O. Mati, Sarojini Nagar, Lucknow, UP, 226002, India.
Kumar P; National Institute of Pharmaceutical Education and Research (NIPER-Raebareli), Bijnor-Sisendi Road, CRPF Base Camp, P.O. Mati, Sarojini Nagar, Lucknow, UP, 226002, India.
Flora SJS; National Institute of Pharmaceutical Education and Research (NIPER-Raebareli), Bijnor-Sisendi Road, CRPF Base Camp, P.O. Mati, Sarojini Nagar, Lucknow, UP, 226002, India. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Dec; Vol. 132, pp. 110871. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Arsenites*
Nanoparticles*
Sodium Compounds*
Antioxidants/*pharmacology
Arsenic Poisoning/*drug therapy
Brain/*drug effects
Chelating Agents/*pharmacology
Lipids/*chemistry
Oxidative Stress/*drug effects
Succimer/*analogs & derivatives
Animals ; Antioxidants/chemistry ; Arsenic Poisoning/etiology ; Arsenic Poisoning/metabolism ; Arsenic Poisoning/physiopathology ; Behavior, Animal/drug effects ; Biomarkers/blood ; Brain/metabolism ; Brain/physiopathology ; Chelating Agents/chemistry ; Disease Models, Animal ; Drug Compounding ; Male ; Motor Activity/drug effects ; Rats, Transgenic ; Succimer/chemistry ; Succimer/pharmacology
Czasopismo naukowe
Tytuł :
Iron chelators for acute stroke.
Autorzy :
Van der Loo LE; Department of Neurosurgery, Maastricht University Medical Centre, Maastricht, Netherlands.
Aquarius R; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, Netherlands.
Teernstra O; Department of Neurosurgery, Maastricht University Medical Centre, Maastricht, Netherlands.
Klijn K; Department of Neurology, Radboud University Medical Center, Nijmegen, Netherlands.
Menovsky T; Department of Neurosurgery, Antwerp University Hospital, Antwerp, Belgium.
van Dijk JMC; Department of Neurosurgery, University Medical Center Groningen, Gronigen, Netherlands.
Bartels R; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, Netherlands.
Boogaarts HD; Department of Neurosurgery, Radboud University Medical Centre, Nijmegen, Netherlands.
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Źródło :
The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2020 Nov 24; Vol. 11. Cochrane AN: CD009280. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Deferoxamine/*therapeutic use
Hemorrhagic Stroke/*drug therapy
Iron Chelating Agents/*therapeutic use
Neuroprotective Agents/*therapeutic use
Acute Disease ; Bias ; Deferoxamine/adverse effects ; Hemorrhagic Stroke/mortality ; Humans ; Iron Chelating Agents/adverse effects ; Neuroprotective Agents/adverse effects ; Placebos/therapeutic use ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Management of Iron Overload in Beta-Thalassemia Patients: Clinical Practice Update Based on Case Series.
Autorzy :
Pinto VM; Centro della Microcitemia e delle Anemie Congenite Ente Ospedaliero Ospedali Galliera, Via Volta 6, 16128 Genoa, Italy.
Forni GL; Centro della Microcitemia e delle Anemie Congenite Ente Ospedaliero Ospedali Galliera, Via Volta 6, 16128 Genoa, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 20; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Deferoxamine/*administration & dosage
Iron/*metabolism
Iron Chelating Agents/*administration & dosage
Iron Overload/*drug therapy
Transfusion Reaction/*complications
beta-Thalassemia/*therapy
Adult ; Blood Transfusion ; Cardiomyopathies/blood ; Cardiomyopathies/etiology ; Cardiomyopathies/physiopathology ; Cardiomyopathies/prevention & control ; Chelation Therapy/adverse effects ; Chelation Therapy/methods ; Deferoxamine/adverse effects ; Drug Monitoring/instrumentation ; Drug Monitoring/methods ; Female ; Heart/drug effects ; Heart/physiopathology ; Humans ; Iron/toxicity ; Iron Chelating Agents/adverse effects ; Iron Overload/blood ; Iron Overload/complications ; Iron Overload/physiopathology ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Middle Aged ; Pancreas/drug effects ; Pancreas/metabolism ; Pancreas/pathology ; Transferrin/metabolism ; Transfusion Reaction/blood ; Transfusion Reaction/physiopathology ; beta-Thalassemia/metabolism ; beta-Thalassemia/pathology
Czasopismo naukowe
Tytuł :
Isolation and Sequencing of Cu-, Fe-, and Zn-Binding Whey Peptides for Potential Neuroprotective Applications as Multitargeted Compounds.
Autorzy :
Caetano-Silva ME; Center of Food Science and Quality, CCQA, Institute of Food Technology, ITAL, Campinas, 13070-178 Campinas, Brazil.
Simabuco FM; Multidisciplinary Laboratory of Food and Health, LABMAS, School of Applied Sciences, FCA, University of Campinas, UNICAMP, Limeira, 13484-350 Limeira, Brazil.
Bezerra RMN; Multidisciplinary Laboratory of Food and Health, LABMAS, School of Applied Sciences, FCA, University of Campinas, UNICAMP, Limeira, 13484-350 Limeira, Brazil.
da Silva DC; Center of Food Science and Quality, CCQA, Institute of Food Technology, ITAL, Campinas, 13070-178 Campinas, Brazil.
Barbosa EA; Laboratory for the Synthesis and Analysis of Biomolecules, Institute of Chemistry, IQ, University of Brasília, Brasília, 70910-900 Distrito Federal, Brazil.; Research Center in Morphology and Applied Immunology, NuPMIA, Morphology Area, Faculty of Medicine, University of Brasília, UnB, Brasília, 70910-900 Distrito Federal, Brazil.
Moreira DC; Research Center in Morphology and Applied Immunology, NuPMIA, Morphology Area, Faculty of Medicine, University of Brasília, UnB, Brasília, 70910-900 Distrito Federal, Brazil.
Brand GD; Laboratory for the Synthesis and Analysis of Biomolecules, Institute of Chemistry, IQ, University of Brasília, Brasília, 70910-900 Distrito Federal, Brazil.
Leite JRSA; Research Center in Morphology and Applied Immunology, NuPMIA, Morphology Area, Faculty of Medicine, University of Brasília, UnB, Brasília, 70910-900 Distrito Federal, Brazil.
Pacheco MTB; Center of Food Science and Quality, CCQA, Institute of Food Technology, ITAL, Campinas, 13070-178 Campinas, Brazil.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2020 Nov 04; Vol. 68 (44), pp. 12433-12443. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Chelating Agents/*chemistry
Copper/*chemistry
Iron/*chemistry
Neuroprotective Agents/*chemistry
Peptides/*chemistry
Whey/*chemistry
Zinc/*chemistry
Animals ; Cattle ; Chelating Agents/isolation & purification ; Neuroprotective Agents/isolation & purification ; Peptides/isolation & purification ; Whey Proteins/chemistry
Czasopismo naukowe

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