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Tytuł:
A Click Chemistry-Based Artificial Metallo-Nuclease.
Autorzy:
Gibney A; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
de Paiva REF; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
Singh V; Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Fox R; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
Thompson D; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, Department of Physics, University of Limerick, Ireland.
Hennessy J; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
Slator C; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
McKenzie CJ; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.
Johansson P; Laboratory of Clinical Chemistry, Sahlgrenska University Hospital Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Sweden.
McKee V; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.
Westerlund F; Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.
Kellett A; SSPC, the, Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Dublin, Ireland.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Sep 18; Vol. 62 (38), pp. e202305759. Date of Electronic Publication: 2023 Jul 04.
Typ publikacji:
Journal Article
MeSH Terms:
Click Chemistry*
Copper*/chemistry
Leukocytes, Mononuclear/metabolism ; Ligands ; DNA/chemistry ; Azides/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Sulfur-fluoride exchange (SuFEx)-enabled lead discovery of AChE inhibitors by fragment linking strategies.
Autorzy:
Zhang Z; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Zhang SL; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Wu C; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Li HH; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Zha L; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Shi J; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
Liu X; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China. Electronic address: .
Qin HL; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, 430070, China. Electronic address: .
Tang W; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Sep 05; Vol. 257, pp. 115502. Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Fluorides*/chemistry
Sulfur Compounds*/chemistry
Animals ; Mice ; Molecular Structure ; Click Chemistry ; Sulfonamides/pharmacology ; Sulfur/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Intelligent gold nanoparticles for malignant tumor treatment via spontaneous copper manipulation and on-demand photothermal therapy based on copper induced click chemistry.
Autorzy:
Yin T; Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
Yang T; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China.
Chen L; Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
Tian R; Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
Cheng C; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China.
Weng L; Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
Zhang Y; School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, China. Electronic address: .
Chen X; Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an, 710049, China. Electronic address: .
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Źródło:
Acta biomaterialia [Acta Biomater] 2023 Aug; Vol. 166, pp. 485-495. Date of Electronic Publication: 2023 Apr 29.
Typ publikacji:
Journal Article
MeSH Terms:
Metal Nanoparticles*/therapeutic use
Metal Nanoparticles*/chemistry
Nanoparticles*/chemistry
Neoplasms*/pathology
Animals ; Mice ; Gold/pharmacology ; Gold/chemistry ; Copper/pharmacology ; Copper/chemistry ; Photothermal Therapy ; Click Chemistry ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Szczegóły
Tytuł:
Optimization of microwave-assisted extraction of antioxidant compounds from spring onion leaves using Box-Behnken design.
Autorzy:
Aquino G; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.; PhD Program in Drug Discovery and Development, University of Salerno, Fisciano, SA, Italy.
Basilicata MG; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy. .
Crescenzi C; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Vestuto V; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Salviati E; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Cerrato M; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Ciaglia T; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Sansone F; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Pepe G; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
Campiglia P; Department of Pharmacy, University of Salerno, 84084, Fisciano, SA, Italy.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 10; Vol. 13 (1), pp. 14923. Date of Electronic Publication: 2023 Sep 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Onions*/chemistry
Plant Leaves*/chemistry
Biphenyl Compounds*/isolation & purification
Picrates*/isolation & purification
Plant Extracts/chemistry ; Solid Waste ; Microwaves ; Hep G2 Cells ; Humans ; Green Chemistry Technology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Medicinal Chemistry Perspectives on Recent Advances in Src Kinase Inhibitors as a Potential Target for the Development of Anticancer Agents: Biological Profile, Selectivity, Structure-Activity Relationship.
Autorzy:
Teli G; Integrated Drug Discovery Center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, Karnataka, India.
Pal R; Integrated Drug Discovery Center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, Karnataka, India.
Maji L; Integrated Drug Discovery Center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, Karnataka, India.
Sengupta S; Integrated Drug Discovery Center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, Karnataka, India.
Raghavendra NM; Department of Pharmaceutical Sciences, College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, Karnataka, India.
Matada GSP; Integrated Drug Discovery Center, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, Karnataka, India.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Sep; Vol. 20 (9), pp. e202300515. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
src-Family Kinases*/chemistry
src-Family Kinases*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases/metabolism ; Chemistry, Pharmaceutical ; Structure-Activity Relationship ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
A 3D paper microfluidic device for enzyme-linked assays: Application to DNA analysis.
Autorzy:
Toldrà A; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden.
Chondrogiannis G; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden.
Hamedi MM; School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden.
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Źródło:
Biotechnology journal [Biotechnol J] 2023 Sep; Vol. 18 (9), pp. e2300143. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Microfluidics*/instrumentation
Paper*
Chemistry Techniques, Analytical*/instrumentation
Chemistry Techniques, Analytical*/methods
Collodion/chemistry ; Chromogenic Compounds/chemistry ; Mobile Applications ; Proteins/analysis ; Nucleic Acids/analysis ; Limit of Detection
Czasopismo naukowe
Szczegóły
Tytuł:
Design of mirtazapine solid dispersion with different carriers' systems: optimization, in vitro evaluation, and bioavailability assessment.
Autorzy:
Aldeeb RAE; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, 12582, Egypt. .
Mahdy MAE; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
El-Nahas HM; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Musallam AA; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, 12582, Egypt.
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Źródło:
Drug delivery and translational research [Drug Deliv Transl Res] 2023 Sep; Vol. 13 (9), pp. 2340-2352. Date of Electronic Publication: 2023 Mar 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemistry, Pharmaceutical*/methods
Polymers*/chemistry
Animals ; Rabbits ; Spectroscopy, Fourier Transform Infrared/methods ; Mirtazapine ; Biological Availability ; Povidone/chemistry ; X-Ray Diffraction ; Solubility ; Water ; Calorimetry, Differential Scanning ; Drug Carriers/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Bacterial nitric oxide reductase (NorBC) models employing click chemistry.
Autorzy:
Harland JB; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, United States.
Samanta S; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, United States.
Lehnert N; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, United States. Electronic address: .
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Źródło:
Journal of inorganic biochemistry [J Inorg Biochem] 2023 Sep; Vol. 246, pp. 112280. Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Nitric Oxide*/metabolism
Click Chemistry*
Iron/chemistry ; Bacteria/metabolism ; Heme/chemistry ; Oxidation-Reduction
Czasopismo naukowe
Szczegóły
Tytuł:
Green synthesised AuNps using Ajuga Bracteosa extract and AuNps-Free supernatant exhibited equivalent antibacterial and anticancerous efficacies.
Autorzy:
Raja SA; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
Andleeb S; Microbial Biotechnology Laboratory, Department of Zoology, The University of Azad Jammu and Kashmir, King Abdullah Campus, Muzaffarabad, Pakistan.
Javed A; Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan.
Sabahat S; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
Parvaiz F; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
Mureed H; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
Ahmad S; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
Naz F; Department of Bioscience, COMSATS University, Islamabad, Pakistan.
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Źródło:
PloS one [PLoS One] 2023 Aug 07; Vol. 18 (8), pp. e0282485. Date of Electronic Publication: 2023 Aug 07 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Ajuga*/chemistry
Metal Nanoparticles*/chemistry
Humans ; Propionates ; Gold/chemistry ; Escherichia coli ; Ligands ; HEK293 Cells ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Staphylococcus aureus ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Microbial Sensitivity Tests ; Green Chemistry Technology/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bioconjugation of a Near-Infrared DNA-Stabilized Silver Nanocluster to Peptides and Human Insulin by Copper-Free Click Chemistry.
Autorzy:
Rück V; Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.
Mishra NK; Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark.
Sørensen KK; Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark.
Liisberg MB; Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.
Sloth AB; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.; Cluster for Molecular Imaging, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.
Cerretani C; Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.
Mollerup CB; Department of Forensic Medicine, University of Copenhagen, Frederik V's Vej 11, 2100 Copenhagen, Denmark.
Kjaer A; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.; Cluster for Molecular Imaging, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.
Lou C; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Jensen KJ; Department of Chemistry, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark.
Vosch T; Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.
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Źródło:
Journal of the American Chemical Society [J Am Chem Soc] 2023 Aug 02; Vol. 145 (30), pp. 16771-16777. Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Silver*/chemistry
Metal Nanoparticles*/chemistry
Humans ; Cricetinae ; Animals ; CHO Cells ; Click Chemistry ; Cricetulus ; DNA/chemistry ; Insulin ; Peptides ; Spectrometry, Fluorescence
Czasopismo naukowe
Szczegóły
Tytuł:
Synthesis of Multifunctional Protein-Polymer Conjugates via Oxygen-tolerant, Aqueous Copper-Mediated Polymerization, and Bioorthogonal Click Chemistry.
Autorzy:
Voutyritsa E; Department of Materials Science and Technology, University of Crete, Heraklion, Crete, 70013, Greece.
Gryparis C; Department of Materials Science and Technology, University of Crete, Heraklion, Crete, 70013, Greece.
Theodorou A; Department of Materials Science and Technology, University of Crete, Heraklion, Crete, 70013, Greece.
Velonia K; Department of Materials Science and Technology, University of Crete, Heraklion, Crete, 70013, Greece.
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Źródło:
Macromolecular rapid communications [Macromol Rapid Commun] 2023 Aug; Vol. 44 (16), pp. e2200976. Date of Electronic Publication: 2023 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Copper*/chemistry
Click Chemistry*
Polymerization ; Polymers/chemistry ; Serum Albumin, Bovine ; Acrylates ; Methacrylates ; Alkynes/chemistry ; Azides/chemistry ; Cycloaddition Reaction
Czasopismo naukowe
Szczegóły
Tytuł:
Compartmentalized Intracellular Click Chemistry with Biodegradable Polymersomes.
Autorzy:
Oerlemans RAJF; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Shao J; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Huisman SGAM; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Li Y; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Abdelmohsen LKEA; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
van Hest JCM; Department of Bio-medical engineering and Chemical engineering & Chemistry, Eindhoven University of Technology: Technische Universiteit Eindhoven, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
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Źródło:
Macromolecular rapid communications [Macromol Rapid Commun] 2023 Aug; Vol. 44 (16), pp. e2200904. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Click Chemistry*
Artificial Cells*
Catalysis ; Copper/chemistry ; Alkynes/chemistry ; Cycloaddition Reaction
Czasopismo naukowe
Szczegóły
Tytuł:
Green Synthesis of Silver Nanoparticles Using Salvadora persica and Caccinia macranthera Extracts: Cytotoxicity Analysis and Antimicrobial Activity Against Antibiotic-Resistant Bacteria.
Autorzy:
Khojasteh-Taheri R; Antimicrobial Resistance Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghasemi A; Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Meshkat Z; Antimicrobial Resistance Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sabouri Z; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohtashami M; Department of Microbiology, Neyshabur Islamic Azad University of Sciences, Neyshabur, Iran. .
Darroudi M; Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran. .; Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. .
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Źródło:
Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2023 Aug; Vol. 195 (8), pp. 5120-5135. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Salvadoraceae*/chemistry
Metal Nanoparticles*/chemistry
Anti-Bacterial Agents/chemistry ; Silver/pharmacology ; Silver/chemistry ; Bacteria ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Microbial Sensitivity Tests ; Green Chemistry Technology ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Szczegóły
Tytuł:
Sulfur(VI) fluorides as tools in biomolecular and medicinal chemistry.
Autorzy:
Carneiro SN; Department of Chemistry, Pomona College, Claremont, California 91711, USA. .
Khasnavis SR; Department of Chemistry, Pomona College, Claremont, California 91711, USA. .
Lee J; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. .
Butler TW; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. .
Majmudar JD; Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, USA.
Am Ende CW; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. .
Ball ND; Department of Chemistry, Pomona College, Claremont, California 91711, USA. .
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2023 Feb 15; Vol. 21 (7), pp. 1356-1372. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Fluorides*/chemistry
Chemistry, Pharmaceutical*
Molecular Structure ; Sulfur/chemistry ; Click Chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
The 2022 Nobel Prize in Chemistry for the development of click chemistry and bioorthogonal chemistry.
Autorzy:
Zaia J; Dept. of Biochemistry, Boston University, 670 Albany St. Rm. 509, Boston, MA, 02118, USA. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2023 Feb; Vol. 415 (4), pp. 527-532. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Click Chemistry*/methods
Nobel Prize*
Proteins ; Protein Processing, Post-Translational ; Proteomics/methods ; Chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
DNA templated Click Chemistry via 5-vinyl-2'-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells.
Autorzy:
Li Y; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany. Electronic address: .
Ling Y; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Loehr MO; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
Chaabane S; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Cheng OW; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Zhao K; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
Wu C; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Büscher M; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Weber J; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Stomakhine D; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
Munker M; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Pientka R; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Christ SB; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
Dobbelstein M; Department of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, 37077 Göttingen, Germany.
Luedtke NW; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 1Y6, Canada.
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Źródło:
Life sciences [Life Sci] 2023 Oct 01; Vol. 330, pp. 122000. Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Click Chemistry*
Neoplasms*
Humans ; Acridines/pharmacology ; DNA Damage ; DNA/chemistry ; Apoptosis
Czasopismo naukowe
Szczegóły
Tytuł:
Click-Chemistry-Enabled Nanopipettes for the Capture and Dynamic Analysis of a Single Mitochondrion inside One Living Cell.
Autorzy:
Liu K; The State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210093, China.
Zhang Z; The State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210093, China.
Liu R; School of Chemical Sciences, University of Chinese Academy of Science, Beijing, 100190, China.
Li JP; The State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210093, China.
Jiang D; The State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210093, China.
Pan R; The State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, Jiangsu, 210093, China.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Aug 21; Vol. 62 (34), pp. e202303053. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitochondria*/chemistry
Mitochondria*/metabolism
Cell Survival ; Click Chemistry/instrumentation ; Click Chemistry/methods ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Mapping the Progress in Surface Plasmon Resonance Analysis of Phytogenic Silver Nanoparticles with Colorimetric Sensing Applications.
Autorzy:
Paul TK; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.; ZR Research Institute for Advanced Materials, Sherpur, 2100, Bangladesh.
Jalil MA; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.
Repon MR; Laboratory of Plant Physiology, Nature Research Center, Akademijos g. 2, 08412, Vilnius, Lithuania.; Department of Production Engineering, Faculty of Mechanical Engineering and Design, Kaunas University of Technology, Studentu 56, LT-51424, Kaunas, Lithuania.
Alim MA; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.; ZR Research Institute for Advanced Materials, Sherpur, 2100, Bangladesh.
Islam T; ZR Research Institute for Advanced Materials, Sherpur, 2100, Bangladesh.; Department of Textile Engineering, Mawlana Bhashani Science and Technology University, Tangail, 1902, Bangladesh.
Rahman ST; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.
Paul A; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.
Rhaman M; Department of Textile Engineering, Faculty of Mechanical Engineering, Khulna, University of Engineering & Technology, Khulna, 9203, Bangladesh.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Aug; Vol. 20 (8), pp. e202300510. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Surface Plasmon Resonance*
Metal Nanoparticles*/chemistry
Silver/chemistry ; Colorimetry/methods ; Anti-Bacterial Agents/chemistry ; Plant Extracts/chemistry ; Green Chemistry Technology
Czasopismo naukowe
Szczegóły
Tytuł:
Chromone Containing Hybrid Analogs: Synthesis and Applications in Medicinal Chemistry.
Autorzy:
Auti PS; Laboratory of Natural Product Chemistry, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS Pilani), Pilani Campus, Pilani, 333031, Rajasthan, India.
Jagetiya S; Laboratory of Natural Product Chemistry, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS Pilani), Pilani Campus, Pilani, 333031, Rajasthan, India.
Paul AT; Laboratory of Natural Product Chemistry, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS Pilani), Pilani Campus, Pilani, 333031, Rajasthan, India.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Aug; Vol. 20 (8), pp. e202300587. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Chemistry, Pharmaceutical*
Chromones*/chemistry
Donepezil ; Drug Discovery ; Structure-Activity Relationship ; Tacrine/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Green Synthesis of Genistein-Fortified Zinc Ferrite Nanoparticles as a Potent Hepatic Cancer Inhibitor: Validation through Experimental and Computational Studies.
Autorzy:
Otuechere CA; Department of Biochemistry, Faculty of Basic Medical Sciences, Redeemer's University, 232101, Ede, Nigeria.; Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, 211007, Prayagraj, India.
Neupane NP; Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, 211007, Prayagraj, India.
Adewuyi A; Department of Chemical Sciences, Faculty of Natural Sciences, Redeemer's University, 232101, Ede, Nigeria.
Pathak P; Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, 211007, Prayagraj, India.; Laboratory of Computational Modeling of Drugs, Higher Medical and Biological School, South Ural State University, 454008, Chelyabinsk, Russia.
Novak J; Department of Biotechnology, University of Rijeka, 51000, Rijeka, Croatia.; Center for Artificial Intelligence and Cybersecurity, University of Rijeka, 51000, Rijeka, Croatia.
Grishina M; Laboratory of Computational Modeling of Drugs, Higher Medical and Biological School, South Ural State University, 454008, Chelyabinsk, Russia.
Khalilullah H; Department of Pharmaceutical Chemistry and Pharmacognosy, Unaizah College of Pharmacy, Qassim University, 51911, Unayzah, Saudi Arabia.
Jaremko M; Smart-Health Initiative (SHI) and Red Sea Research Center (RSRC), Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), 23955-6900, Thuwal, Saudi Arabia.
Verma A; Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, 211007, Prayagraj, India.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Aug; Vol. 20 (8), pp. e202300719. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
Liver Neoplasms*/drug therapy
Metal Nanoparticles*/chemistry
Humans ; Zinc ; Genistein/pharmacology ; Spectroscopy, Fourier Transform Infrared ; Plant Extracts/chemistry ; X-Ray Diffraction ; Green Chemistry Technology ; Anti-Bacterial Agents/pharmacology
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 6117078

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