Skocz do pozycji: 1.

Tytuł:

Modern approaches to therapeutic oligonucleotide manufacturing.

Autorzy:

Obexer R; Manchester Institute of Biotechnology, Department of Chemistry, University of Manchester, Manchester, UK.
Nassir M; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Moody ER; Manchester Institute of Biotechnology, Department of Chemistry, University of Manchester, Manchester, UK.
Baran PS; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Lovelock SL; Manchester Institute of Biotechnology, Department of Chemistry, University of Manchester, Manchester, UK.

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Źródło:

Science (New York, N.Y.) [Science] 2024 Apr 12; Vol. 384 (6692), pp. eadl4015. Date of Electronic Publication: 2024 Apr 12.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Oligonucleotides*/chemical synthesis
Oligonucleotides*/therapeutic use
Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

Organic Synthesis and Current Understanding of the Mechanisms of CFTR Modulator Drugs Ivacaftor, Tezacaftor, and Elexacaftor.

Autorzy:

Ferreira FC; Biosystems & Integrative Sciences Institute (BioISI), Faculty of Sciences, University of Lisbon, 1749-016 Lisbon, Portugal.
Buarque CD; Department of Chemistry, Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro 22435-900, RJ, Brazil.
Lopes-Pacheco M; Biosystems & Integrative Sciences Institute (BioISI), Faculty of Sciences, University of Lisbon, 1749-016 Lisbon, Portugal.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2024 Feb 10; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 10.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Cystic Fibrosis Transmembrane Conductance Regulator*/metabolism
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/genetics
Cystic Fibrosis*/metabolism
Aminopyridines*
Indoles*
Pyrazoles*
Pyridines*
Pyrrolidines*
Quinolones*
Humans ; Quality of Life ; Benzodioxoles/pharmacology ; Benzodioxoles/therapeutic use ; Aminophenols/pharmacology ; Aminophenols/therapeutic use ; Mutation ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Exploring the Formation Kinetics of Octacalcium Phosphate from Alpha-Tricalcium Phosphate: Synthesis Scale-Up, Determination of Transient Phases, Their Morphology and Biocompatibility.

Autorzy:

Kovrlija I; Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre, Faculty of Materials Science and Applied Chemistry, Institute of General Chemical Engineering, Riga Technical University, Pulka 3, LV-1007 Riga, Latvia.
Menshikh K; Center for Translational Research on Autoimmune and Allergic Disease-CAAD, Department of Health Sciences, Università del Piemonte Orientale, 28100 Novara, Italy.
Marsan O; CIRIMAT, Université de Toulouse, CNRS, Toulouse INP-ENSIACET, 4 Allée Emile Monso, CEDEX 4, 31030 Toulouse, France.
Rey C; CIRIMAT, Université de Toulouse, CNRS, Toulouse INP-ENSIACET, 4 Allée Emile Monso, CEDEX 4, 31030 Toulouse, France.
Combes C; CIRIMAT, Université de Toulouse, CNRS, Toulouse INP-ENSIACET, 4 Allée Emile Monso, CEDEX 4, 31030 Toulouse, France.
Locs J; Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre, Faculty of Materials Science and Applied Chemistry, Institute of General Chemical Engineering, Riga Technical University, Pulka 3, LV-1007 Riga, Latvia.; Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1007 Riga, Latvia.
Loca D; Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre, Faculty of Materials Science and Applied Chemistry, Institute of General Chemical Engineering, Riga Technical University, Pulka 3, LV-1007 Riga, Latvia.; Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1007 Riga, Latvia.

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Źródło:

Biomolecules [Biomolecules] 2023 Mar 02; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 02.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemistry Techniques, Synthetic*
Calcium Phosphates*/chemical synthesis
Calcium Phosphates*/chemistry
Kinetics ; Spectroscopy, Fourier Transform Infrared ; Microscopy, Electron, Scanning ; Spectrum Analysis, Raman ; Lasers ; X-Ray Diffraction ; Particle Size ; Cell Survival ; Cell Shape ; Humans ; Mesenchymal Stem Cells/cytology ; Drug Delivery Systems ; Hydrolysis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates.

Autorzy:

Neto BAD; Laboratory of Medicinal and Technological Chemistry, Institute of Chemistry (IQ-UnB), Campus Universitário Darcy Ribeiro, University of Brasília, Brasília 70910-900, DF, Brazil.
Beck PS; Laboratory of Medicinal and Technological Chemistry, Institute of Chemistry (IQ-UnB), Campus Universitário Darcy Ribeiro, University of Brasília, Brasília 70910-900, DF, Brazil.
Sorto JEP; Laboratory of Medicinal and Technological Chemistry, Institute of Chemistry (IQ-UnB), Campus Universitário Darcy Ribeiro, University of Brasília, Brasília 70910-900, DF, Brazil.; Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife 50670-901, PE, Brazil.
Eberlin MN; MackMass Laboratory, PPGENM, School of Engineering, Mackenzie Presbyterian University São Paulo, São Paulo 01302-907, SP, Brazil.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Nov 04; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 04.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*/methods
Transition Temperature*

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

The Recycling of Substandard Rocket Fuel N,N-Dimethylhydrazine via the Involvement of Its Hydrazones Derived from Glyoxal, Acrolein, Metacrolein, Crotonaldehyde, and Formaldehyde in Organic Synthesis.

Autorzy:

Ivanova E; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Osipova M; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Vasilieva T; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Eremkin A; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Markova S; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Zazhivihina E; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Smirnova S; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.
Mitrasov Y; Organic and Pharmaceutical Chemistry Department, Yakovlev Chuvash State Pedagogical University, K. Marx Street, 38, 428000 Cheboksary, Russia.
Nasakin O; Organic and Pharmaceutical Chemistry Department, Ulyanov Chuvash State University, Moskovsky Prospect, 15, 428015 Cheboksary, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 06; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 06.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Acrolein*
Glyoxal*
Dimethylhydrazines/chemistry ; Formaldehyde ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

RetroComposer: Composing Templates for Template-Based Retrosynthesis Prediction.

Autorzy:

Yan C; Computer Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Zhao P; Tencent AI Lab, Shenzhen 518054, China.
Lu C; Tencent AI Lab, Shenzhen 518054, China.
Yu Y; Tencent AI Lab, Shenzhen 518054, China.
Huang J; Computer Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA.

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Źródło:

Biomolecules [Biomolecules] 2022 Sep 19; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 19.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms:

Chemistry Techniques, Synthetic*/methods
Machine Learning*
Models, Chemical

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era.

Autorzy:

Rossino G; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Marchese E; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.; Department of Health Sciences, University 'Magna Graecia', Viale Europa, 88100 Catanzaro, Italy.
Galli G; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Verde F; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Finizio M; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Serra M; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Linciano P; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Collina S; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Oct 19; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 19.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Peptides*/therapeutic use
Peptides*/chemistry
Chemistry Techniques, Synthetic ; Pharmaceutical Preparations

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Concise syntheses of GB22, GB13, and himgaline by cross-coupling and complete reduction.

Autorzy:

Landwehr EM; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Baker MA; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Oguma T; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Burdge HE; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Kawajiri T; Department of Chemistry, Scripps Research, La Jolla, CA, USA.
Shenvi RA; Department of Chemistry, Scripps Research, La Jolla, CA, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2022 Mar 18; Vol. 375 (6586), pp. 1270-1274. Date of Electronic Publication: 2022 Mar 17.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Alkaloids*/chemical synthesis
Alkaloids*/chemistry
Chemistry Techniques, Synthetic*
Heterocyclic Compounds*/chemical synthesis
Heterocyclic Compounds*/chemistry
Magnoliopsida ; Oxidation-Reduction ; Stereoisomerism ; Trees

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Total synthesis of himastatin.

Autorzy:

D'Angelo KA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Schissel CK; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; The Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA 02142, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Environmental Health Sciences, MIT, Cambridge, MA 02139, USA.
Movassaghi M; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2022 Feb 25; Vol. 375 (6583), pp. 894-899. Date of Electronic Publication: 2022 Feb 24.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemistry Techniques, Synthetic*
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacillus subtilis/drug effects ; Bacillus subtilis/ultrastructure ; Cell Membrane/drug effects ; Cell Membrane/ultrastructure ; Dimerization ; Molecular Structure ; Peptides, Cyclic/chemical synthesis ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/pharmacology ; Stereoisomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 10.

Tytuł:

Modular terpene synthesis enabled by mild electrochemical couplings.

Autorzy:

Harwood SJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
Palkowitz MD; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.
Gannett CN; Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14853, USA.
Perez P; Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
Yao Z; Asymchem Life Sciences (Tianjin) Co., Ltd., TEDA Tianjin, 300457, P.R. China.
Sun L; Asymchem Life Sciences (Tianjin) Co., Ltd., TEDA Tianjin, 300457, P.R. China.
Abruña HD; Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14853, USA.
Anderson SL; Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
Baran PS; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2022 Feb 18; Vol. 375 (6582), pp. 745-752. Date of Electronic Publication: 2022 Feb 17.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms:

Chemistry Techniques, Synthetic*
Terpenes/*chemical synthesis
Biological Products/chemical synthesis ; Biological Products/chemistry ; Catalysis ; Cyclization ; Electrochemical Techniques ; Electrodes ; Metal Nanoparticles ; Nickel/chemistry ; Oxidation-Reduction ; Silver ; Stereoisomerism ; Terpenes/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties.

Autorzy:

Mastromarino M; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.
Niso M; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.
Abate C; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.
Proschak E; Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany.
Dubiel M; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.
Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.
Castro M; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Avda de Barcelona s/n, 15782 Santiago de Compostela, Spain.
Lacivita E; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.
Leopoldo M; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Feb 15; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 15.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Neuroprotective Agents/*chemistry
Neuroprotective Agents/*pharmacology
Cell Line ; Cell Survival/drug effects ; Dopamine D2 Receptor Antagonists ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Receptors, Dopamine/chemistry ; Receptors, Dopamine/metabolism ; Receptors, Serotonin/chemistry ; Receptors, Serotonin/metabolism ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

Drug Design, Synthesis and Biological Evaluation of Heterocyclic Molecules as Anti-Inflammatory Agents.

Autorzy:

Savjani J; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.
Variya B; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Patel S; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.
Mulamkattil S; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.
Amin H; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.
Butani S; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.
Allam A; Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 65211, Egypt.
Ajarem J; Zoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Shah H; J-Star Research Inc., 6 Cedar Brook Drive, Cranbury, NJ 08512, USA.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Feb 14; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 14.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Anti-Inflammatory Agents, Non-Steroidal/*chemistry
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Heterocyclic Compounds/*chemistry
Heterocyclic Compounds/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Biomarkers ; Cyclooxygenase 2 Inhibitors/chemical synthesis ; Cyclooxygenase 2 Inhibitors/chemistry ; Cyclooxygenase 2 Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Heterocyclic Compounds/chemical synthesis ; Indomethacin/chemical synthesis ; Indomethacin/chemistry ; Indomethacin/pharmacology ; Ligands ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Proteins/chemistry ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3- d ]pyrimidines as Microtubule Targeting Agents.

Autorzy:

Islam F; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Doshi A; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Robles AJ; Department of Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.; Mays Cancer Center, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Quadery TM; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Zhang X; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Zhou X; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
Hamel E; Molecular Pharmacology Branch, Developmental Therapeutics Program, Frederick National Laboratory for Cancer Research, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Mooberry SL; Department of Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.; Mays Cancer Center, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Gangjee A; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Jan 05; Vol. 27 (1). Date of Electronic Publication: 2022 Jan 05.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Pyrimidines/*chemistry
Pyrimidines/*pharmacology
Tubulin Modulators/*chemistry
Tubulin Modulators/*pharmacology
Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm ; Humans ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Protein Multimerization/drug effects ; Pyrimidines/chemical synthesis ; Structure-Activity Relationship ; Tubulin/chemistry ; Tubulin/metabolism ; Tubulin Modulators/chemical synthesis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 14.

Tytuł:

Green Synthesis of Oxoquinoline-1(2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders.

Autorzy:

Ali A; High Altitude Research Center, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Ali A; Department of Pharmacognosy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Warsi MH; Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Rahman MA; Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Ahsan MJ; Department of Pharmaceutical Chemistry, Maharishi Arvind College of Pharmacy, Jaipur 302 039, Rajasthan, India.
Azam F; Department of Pharmaceutical Chemistry & Pharmacognosy, Unaizah College of Pharmacy, Qassim University, Uniazah 51911, Saudi Arabia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Jan 04; Vol. 27 (1). Date of Electronic Publication: 2022 Jan 04.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Green Chemistry Technology*
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Antioxidants/*chemical synthesis
Antioxidants/*pharmacology
Quinolones/*chemistry
Binding Sites ; Catalytic Domain ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 15.

Tytuł:

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.

Autorzy:

Dimitrakis S; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Gavriil ES; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Pousias A; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Lougiakis N; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Marakos P; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Pouli N; Department of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Gioti K; Department of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.
Tenta R; Department of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Dec 31; Vol. 27 (1). Date of Electronic Publication: 2021 Dec 31.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Pyrimidines/*chemical synthesis
Pyrimidines/*pharmacology
Antineoplastic Agents/chemistry ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Molecular Structure ; Pyrimidines/chemistry ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 16.

Tytuł:

Design, synthesis, and biological evaluation of novel urolithins derivatives as potential phosphodiesterase II inhibitors.

Autorzy:

Tang L; Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, 210042, China.; School of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, China.; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Jiang J; Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, 210042, China.; School of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, China.
Song G; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Wang Y; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Zhuang Z; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Tan Y; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Xia Y; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Huang X; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China.
Feng X; School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, 213164, China. .

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Źródło:

Scientific reports [Sci Rep] 2021 Dec 10; Vol. 11 (1), pp. 23792. Date of Electronic Publication: 2021 Dec 10.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Exonucleases/*antagonists & inhibitors
Exonucleases/*chemistry
Phosphodiesterase Inhibitors/*chemistry
Phosphodiesterase Inhibitors/*pharmacology
Binding Sites ; Enzyme Activation/drug effects ; Exonucleases/chemical synthesis ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Phosphodiesterase Inhibitors/chemical synthesis ; Protein Binding ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Ligand-controlled divergent dehydrogenative reactions of carboxylic acids via C-H activation.

Autorzy:

Wang Z; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Hu L; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Chekshin N; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Zhuang Z; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Qian S; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Qiao JX; Discovery Chemistry, Bristol-Myers Squibb, P.O. Box 4000, Princeton, NJ 08543, USA.
Yu JQ; The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2021 Dec 03; Vol. 374 (6572), pp. 1281-1285. Date of Electronic Publication: 2021 Nov 11.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemistry Techniques, Synthetic*
Carbon/*chemistry
Carboxylic Acids/*chemistry
Hydrogen/*chemistry
4-Butyrolactone/analogs & derivatives ; 4-Butyrolactone/chemical synthesis ; 4-Butyrolactone/chemistry ; Carboxylic Acids/chemical synthesis ; Catalysis ; Chemical Phenomena ; Hydrogen Bonding ; Ligands ; Molecular Structure ; Oxidation-Reduction ; Oxygen/chemistry ; Palladium/chemistry ; Pyridines/chemistry ; Pyridones/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

Enantioselective catalytic 1,2-boronate rearrangements.

Autorzy:

Sharma HA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Essman JZ; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Jacobsen EN; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

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Źródło:

Science (New York, N.Y.) [Science] 2021 Nov 05; Vol. 374 (6568), pp. 752-757. Date of Electronic Publication: 2021 Nov 04.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural

MeSH Terms:

Chemistry Techniques, Synthetic*
Boronic Acids/*chemistry
Catalysis ; Esters/chemistry ; Lithium/chemistry ; Molecular Structure ; Stereoisomerism ; Thiourea/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 19.

Tytuł:

Advances in [ F]Trifluoromethylation Chemistry for PET Imaging.

Autorzy:

Francis F; Department of Chemistry, University of Alberta, 11227 Saskatchewan Drive NW, Edmonton, AB T6G 2N4, Canada.
Wuest F; Department of Chemistry, University of Alberta, 11227 Saskatchewan Drive NW, Edmonton, AB T6G 2N4, Canada.; Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Oct 27; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 27.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Fluorine Radioisotopes*/chemistry
Positron-Emission Tomography/*methods
Radiopharmaceuticals/*chemistry
Animals ; Humans ; Isotope Labeling ; Molecular Structure ; Radiochemistry ; Radiopharmaceuticals/chemical synthesis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

Green synthesis of zinc oxide nanoparticles using Elaeagnus angustifolia L. leaf extracts and their multiple in vitro biological applications.

Autorzy:

Iqbal J; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan. .; Department of Botany, Bacha Khan University, Charsadda, Khyber Pakhtunkhwa, Pakistan. .
Abbasi BA; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
Yaseen T; Department of Botany, Bacha Khan University, Charsadda, Khyber Pakhtunkhwa, Pakistan.
Zahra SA; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
Shahbaz A; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
Shah SA; Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Uddin S; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
Ma X; School of Life Sciences, School of Computer Science and Technology, Tiangong University, Tianjin, 300387, China.
Raouf B; Riphah International University, Sector I-14 Campus Hajj Complex Islamabad, Rawalpindi, Pakistan.
Kanwal S; Department of Zoology, Rawalpindi Women University, Rawalpindi, 46000, Pakistan.
Amin W; Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mahmood T; Department of Plant Sciences, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
El-Serehy HA; Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Ahmad P; Botany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia. .; Department of Botany, S. P. College, Srinagar, Jammu and Kashmir, 190001, India. .

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Źródło:

Scientific reports [Sci Rep] 2021 Oct 25; Vol. 11 (1), pp. 20988. Date of Electronic Publication: 2021 Oct 25.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Green Chemistry Technology*
Elaeagnaceae/*chemistry
Metal Nanoparticles/*chemistry
Plant Extracts/*chemistry
Plant Extracts/*pharmacology
Zinc Oxide/*chemistry
Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Microbial Sensitivity Tests ; Spectrum Analysis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 21.

Tytuł:

Total Synthesis of 6-Deoxydihydrokalafungin, a Key Biosynthetic Precursor of Actinorhodin, and Its Epimer.

Autorzy:

Kumamoto T; Department of Synthetic Organic Chemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Kainuma M; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan.
Takahashi A; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan.
Matsuo Y; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan.
Katakawa K; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan.
Taguchi T; National Institute of Health Sciences, Kanagawa 210-9501, Japan.
Ichinose K; Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo 202-8585, Japan.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Oct 22; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 22.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Anthraquinones/chemical synthesis ; Anthraquinones/chemistry ; Anthraquinones/pharmacology ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Oxidation-Reduction ; Stereoisomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 22.

Tytuł:

Design and Synthesis of Novel Betulin Derivatives Containing Thio-/Semicarbazone Moieties as Apoptotic Inducers through Mitochindria-Related Pathways.

Autorzy:

Wang J; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Wu J; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Han Y; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Zhang J; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Lin Y; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Wang H; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Wang J; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Liu J; Research Institute of Medicine & Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Bu M; College of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Oct 21; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 21.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Apoptosis/*drug effects
Mitochondria/*drug effects
Mitochondria/*metabolism
Semicarbazones/*chemistry
Semicarbazones/*pharmacology
Triterpenes/*chemistry
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Biomarkers ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Flow Cytometry ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Metabolic Networks and Pathways/drug effects ; Molecular Structure ; Reactive Oxygen Species/metabolism ; Semicarbazones/chemical synthesis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 23.

Tytuł:

Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole.

Autorzy:

Peroković VP; Department of Chemistry, Faculty of Science, University Zagreb, Horvatovac 102, HR-10000 Zagreb, Croatia.
Car Ž; Department of Chemistry, Faculty of Science, University Zagreb, Horvatovac 102, HR-10000 Zagreb, Croatia.
Draženović J; Department of Chemistry, Faculty of Science, University Zagreb, Horvatovac 102, HR-10000 Zagreb, Croatia.
Stojković R; Division of Molecular Medicine and Division of Molecular Biology, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Milković L; Division of Molecular Medicine and Division of Molecular Biology, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Antica M; Division of Molecular Medicine and Division of Molecular Biology, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Škalamera Đ; Department of Chemistry, Faculty of Science, University Zagreb, Horvatovac 102, HR-10000 Zagreb, Croatia.
Tomić S; Department of Chemistry, Faculty of Science, University Zagreb, Horvatovac 102, HR-10000 Zagreb, Croatia.
Ribić R; Department of Nursing, University Center Varaždin, University North, Jurja Križanića 31b, HR-42000 Varaždin, Croatia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Oct 21; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 21.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Acetylmuramyl-Alanyl-Isoglutamine/*chemistry
Acetylmuramyl-Alanyl-Isoglutamine/*pharmacology
Triazoles/*chemistry
Acetylmuramyl-Alanyl-Isoglutamine/chemical synthesis ; Animals ; Antibody Formation/drug effects ; Dose-Response Relationship, Drug ; Immunologic Factors/chemical synthesis ; Immunologic Factors/chemistry ; Immunologic Factors/pharmacology ; Mice ; Molecular Structure ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

The Application of Microwaves, Ultrasounds, and Their Combination in the Synthesis of Nitrogen-Containing Bicyclic Heterocycles.

Autorzy:

Frecentese F; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Sodano F; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Corvino A; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Schiano ME; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Magli E; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Albrizio S; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Sparaco R; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Andreozzi G; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.
Nieddu M; Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Rimoli MG; Department of Pharmacy, 'Federico II' University of Naples, 80131 Naples, Italy.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Jun 27; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 27.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Microwaves*
Nitrogen*
Chemistry Techniques, Synthetic ; Ultrasonography ; Chemistry, Pharmaceutical

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

Photocatalytic Transformation of Biomass and Biomass Derived Compounds-Application to Organic Synthesis.

Autorzy:

Gómez Fernández MA; CNRS, Université de Reims Champagne-Ardenne, ICMR, Equipe de Photochimie, UFR Sciences, B.P. 1039, 51687 Reims, France.
Hoffmann N; CNRS, Université de Reims Champagne-Ardenne, ICMR, Equipe de Photochimie, UFR Sciences, B.P. 1039, 51687 Reims, France.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Jun 13; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 13.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Carbohydrates*/chemistry
Humans ; Biomass ; Catalysis ; Biopolymers ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

1,3-Butadiynamides the Ethynylogous Ynamides: Synthesis, Properties and Applications in Heterocyclic Chemistry.

Autorzy:

Lenko I; Laboratoire de Chimie Moléculaire et Thio-Organique (LCMT), CNRS UMR 6507, ENSICAEN & UNICAEN, Normandie University, 6 Bd Maréchal Juin, 14050 Caen, France.
Alayrac C; Laboratoire de Chimie Moléculaire et Thio-Organique (LCMT), CNRS UMR 6507, ENSICAEN & UNICAEN, Normandie University, 6 Bd Maréchal Juin, 14050 Caen, France.
Bożek I; Laboratoire de Chimie Moléculaire et Thio-Organique (LCMT), CNRS UMR 6507, ENSICAEN & UNICAEN, Normandie University, 6 Bd Maréchal Juin, 14050 Caen, France.
Witulski B; Laboratoire de Chimie Moléculaire et Thio-Organique (LCMT), CNRS UMR 6507, ENSICAEN & UNICAEN, Normandie University, 6 Bd Maréchal Juin, 14050 Caen, France.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Jun 05; Vol. 28 (11). Date of Electronic Publication: 2023 Jun 05.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Transition Elements*
Chemistry Techniques, Synthetic/methods ; Cycloaddition Reaction ; Molecular Structure ; Silver

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 27.

Tytuł:

Formal [3 + 2] Cycloaddition of α -Imino Esters with Azo Compounds: Facile Construction of Pentasubstituted 1,2,4-Triazoline Skeletons.

Autorzy:

Yoshida Y; Molecular Chirality Research Center, Graduate School of Engineering, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba-shi 263-8522, Japan.
Ida H; Molecular Chirality Research Center, Graduate School of Engineering, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba-shi 263-8522, Japan.
Mino T; Molecular Chirality Research Center, Graduate School of Engineering, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba-shi 263-8522, Japan.
Sakamoto M; Molecular Chirality Research Center, Graduate School of Engineering, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba-shi 263-8522, Japan.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 May 25; Vol. 28 (11). Date of Electronic Publication: 2023 May 25.

Typ publikacji:

Journal Article

MeSH Terms:

Esters*/chemistry
Azo Compounds*
Cycloaddition Reaction ; Chemistry Techniques, Synthetic/methods ; Catalysis ; Stereoisomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

The Bucherer-Bergs Multicomponent Synthesis of Hydantoins-Excellence in Simplicity.

Autorzy:

Kalník M; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Dúbravská cesta 9, SK-845 38 Bratislava, Slovakia.
Gabko P; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Dúbravská cesta 9, SK-845 38 Bratislava, Slovakia.
Bella M; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Dúbravská cesta 9, SK-845 38 Bratislava, Slovakia.
Koóš M; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Dúbravská cesta 9, SK-845 38 Bratislava, Slovakia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Jun 30; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 30.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Agrochemicals/*chemical synthesis
Agrochemicals/*chemistry
Hydantoins/*chemical synthesis
Hydantoins/*chemistry
Molecular Structure

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 29.

Tytuł:

Asymmetric Synthesis of Tetrasubstituted α-Aminophosphonic Acid Derivatives.

Autorzy:

Maestro A; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.; Stratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Del Corte X; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
López-Francés A; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Martínez de Marigorta E; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Palacios F; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.
Vicario J; Departamento de Química Orgánica I, Centro de Investigación y Estudios Avanzados 'Lucio Lascaray'-Facultad de Farmacia, University of the Basque Country, UPV/EHU Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 May 27; Vol. 26 (11). Date of Electronic Publication: 2021 May 27.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Chemistry, Pharmaceutical/*methods
Phosphorous Acids/*analysis
Phosphorous Acids/*chemical synthesis
Amino Acids/chemistry ; Carbon/chemistry ; Catalysis ; Drug Design ; Imines/chemistry ; Molecular Structure ; Nitrogen/chemistry ; Organophosphonates/chemical synthesis ; Palladium/chemistry ; Phosphorus/chemistry ; Rhodium/chemistry ; Stereoisomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 30.

Tytuł:

Synthesis and Modeling of Ezetimibe Analogues.

Autorzy:

Salgado MM; Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.
Manchado A; Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.
Nieto CT; Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.
Díez D; Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.
Garrido NM; Departamento de Química Orgánica, Universidad de Salamanca, 37008 Salamanca, Spain.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 May 22; Vol. 26 (11). Date of Electronic Publication: 2021 May 22.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Ezetimibe/*analogs & derivatives
Ezetimibe/*chemical synthesis
Alleles ; Amides/chemistry ; Amino Acids/chemistry ; Anticholesteremic Agents/administration & dosage ; Anticholesteremic Agents/chemical synthesis ; Cholesterol/blood ; Humans ; Ligands ; Magnetic Resonance Spectroscopy ; Membrane Transport Proteins/metabolism ; Molecular Docking Simulation ; Pyridines/chemistry ; Stereoisomerism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 31.

Tytuł:

Design, Synthetic Strategies, and Therapeutic Applications of Heterofunctional Glycodendrimers.

Autorzy:

Mousavifar L; Glycosciences and Nanomaterial Laboratory, Université du Québec à Montréal, P.O. Box 8888, Succ. Centre-Ville, Montréal, QC H3C 3P8, Canada.
Roy R; Glycosciences and Nanomaterial Laboratory, Université du Québec à Montréal, P.O. Box 8888, Succ. Centre-Ville, Montréal, QC H3C 3P8, Canada.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Apr 22; Vol. 26 (9). Date of Electronic Publication: 2021 Apr 22.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Dendrimers/*chemistry
Dendrimers/*pharmacology
Glycoconjugates/*chemistry
Glycoconjugates/*pharmacology
Carbohydrates/chemistry ; Dendrimers/chemical synthesis ; Drug Development ; Glycoconjugates/chemical synthesis ; Humans ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Molecular Targeted Therapy ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 32.

Tytuł:

Synthesis of New Triazolopyrazine Antimalarial Compounds.

Autorzy:

Johnson DJG; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.
Jenkins ID; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.
Huxley C; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.
Coster MJ; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.
Lum KY; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.; NatureBank, Griffith University, Brisbane, QLD 4111, Australia.
White JM; School of Chemistry and Bio21 Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.
Avery VM; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.; Discovery Biology, Griffith University, Brisbane, QLD 4111, Australia.
Davis RA; Griffith Institute for Drug Discovery, School of Environment and Science, Griffith University, Brisbane, QLD 4111, Australia.; NatureBank, Griffith University, Brisbane, QLD 4111, Australia.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Apr 21; Vol. 26 (9). Date of Electronic Publication: 2021 Apr 21.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Antimalarials/*chemistry
Antimalarials/*pharmacology
Pyrazines/*chemistry
Pyrazines/*pharmacology
Alcohols/chemistry ; Antimalarials/chemical synthesis ; Crystallography, X-Ray ; Humans ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Molecular Structure ; Parasitic Sensitivity Tests ; Plasmodium falciparum/drug effects ; Pyrazines/chemical synthesis ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 33.

Tytuł:

Design and Synthesis of a Novel PLK1 Inhibitor Scaffold Using a Hybridized 3D-QSAR Model.

Autorzy:

Oh Y; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Jung H; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Kim H; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Baek J; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Jun J; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Cho H; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Im D; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.
Hah JM; College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Korea.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2021 Apr 08; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 08.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Quantitative Structure-Activity Relationship*
Cell Cycle Proteins/*chemistry
Protein Kinase Inhibitors/*chemistry
Protein Serine-Threonine Kinases/*chemistry
Proto-Oncogene Proteins/*chemistry
Cell Cycle Proteins/antagonists & inhibitors ; Molecular Conformation ; Protein Binding ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/pharmacology ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Proto-Oncogene Proteins/antagonists & inhibitors ; Polo-Like Kinase 1

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 34.

Tytuł:

Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.

Autorzy:

Hudáčová M; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.
Hamuľaková S; Department of Organic Chemistry, Institute of Chemical Sciences, Faculty of Science, Pavol Jozef Šafárik University in Košice, Moyzesova 11, 040 01 Kosice, Slovakia.
Konkoľová E; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo Náměstí 542/2, 160 00 Prague 6, Czech Republic.
Jendželovský R; Department of Cellular Biology, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.
Vargová J; Department of Cellular Biology, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.
Ševc J; Department of Cellular Biology, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.
Fedoročko P; Department of Cellular Biology, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.
Soukup O; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Janočková J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Ihnatova V; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.
Kučera T; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.
Bzonek P; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Novakova N; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Jun D; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Junova L; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.
Korábečný J; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic.; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic.
Kuča K; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Kožurková M; Department of Biochemistry, Faculty of Science, Pavol Jozef Šafárik University in Košice, Šrobárova 2, 041 54 Košice, Slovakia.; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2021 Apr 07; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 07.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Models, Molecular*
Cholinesterase Inhibitors/*chemistry
Cholinesterase Inhibitors/*pharmacology
Coumarins/*chemistry
Coumarins/*pharmacology
A549 Cells ; Alzheimer Disease/drug therapy ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Cell Cycle/drug effects ; Cell Survival/drug effects ; Cholinesterase Inhibitors/chemical synthesis ; Coumarins/chemical synthesis ; Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; Humans ; Molecular Structure ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 35.

Tytuł:

Organic synthesis and anti-influenza A virus activity of cyclobakuchiols A, B, C, and D.

Autorzy:

Shoji M; Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry, Tokushima Bunri University, Tokushima, Japan.
Esumi T; Faculty of Pharmaceutical Sciences, Institute of Pharmacognosy, Tokushima Bunri University, Tokushima, Japan.
Tanaka N; Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry, Tokushima Bunri University, Tokushima, Japan.
Takeuchi M; Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry, Tokushima Bunri University, Tokushima, Japan.
Yamaji S; Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry, Tokushima Bunri University, Tokushima, Japan.
Watanabe M; Faculty of Pharmaceutical Sciences, Institute of Pharmacognosy, Tokushima Bunri University, Tokushima, Japan.
Takahashi E; Division of Pathology and Metabolome Research for Infectious Disease and Host Defense, Institute for Enzyme Research, University of Tokushima, Tokushima, Japan.
Kido H; Division of Pathology and Metabolome Research for Infectious Disease and Host Defense, Institute for Enzyme Research, University of Tokushima, Tokushima, Japan.
Yamamoto M; Department of Integrative Genomics, Tohoku University Tohoku Medical Megabank Organization, Sendai, Japan.; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kuzuhara T; Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry, Tokushima Bunri University, Tokushima, Japan.

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Źródło:

PloS one [PLoS One] 2021 Mar 26; Vol. 16 (3), pp. e0248960. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Chemistry Techniques, Synthetic*
Antiviral Agents/*chemical synthesis
Antiviral Agents/*pharmacology
Cyclohexanes/*chemical synthesis
Cyclohexanes/*pharmacology
Influenza A virus/*drug effects
Animals ; Antiviral Agents/chemistry ; Cell Survival/drug effects ; Cyclohexanes/chemistry ; Cyclohexanes/toxicity ; Dogs ; Gene Expression Regulation, Viral/drug effects ; Host-Pathogen Interactions/drug effects ; Image Processing, Computer-Assisted ; Influenza A virus/growth & development ; Interferon-beta/genetics ; Interferon-beta/metabolism ; Madin Darby Canine Kidney Cells ; Myxovirus Resistance Proteins/genetics ; Myxovirus Resistance Proteins/metabolism ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; NF-E2-Related Factor 2/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Viral Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 36.

Tytuł:

Recent Advances in the Synthesis of Selenophenes and Their Derivatives.

Autorzy:

Hellwig PS; Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Peglow TJ; Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Penteado F; Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Bagnoli L; Group of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy.
Perin G; Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Lenardão EJ; Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 13; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 13.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*/methods
Chemistry Techniques, Synthetic*/trends
Heterocyclic Compounds/*chemical synthesis
Organoselenium Compounds/*chemical synthesis
Cyclization ; Heterocyclic Compounds/chemistry ; Heterocyclic Compounds/pharmacology ; Molecular Structure ; Organoselenium Compounds/chemistry ; Organoselenium Compounds/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 37.

Tytuł:

Editorial to the Special Issue "Total Synthesis of Natural Products: A Themed Issue Dedicated to Professor Dr. Dieter Schinzer for His 65th Birthday".

Autorzy:

Koskinen AMP; Department of Chemistry and Materials Science, Aalto University School of Chemical Engineering, Kemistintie 1, P.O. Box 16100, 02150 Espoo, Finland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 10; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 10.

Typ publikacji:

Biography; Editorial; Historical Article; Introductory Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*/history
Chemistry Techniques, Synthetic*/methods
Famous Persons*
Biological Products/*chemical synthesis
Biological Products/chemistry ; Biological Products/pharmacology ; History, 20th Century ; History, 21st Century ; Humans

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

Recent Advances in One-Pot Modular Synthesis of 2-Quinolones.

Autorzy:

Hong WP; School of Advanced Materials and Chemical Engineering, Daegu Catholic University, 13-13, Hayang-ro, Hayang-eup, Gyeongsan-si, Gyeongbuk 38430, Korea.
Shin I; Department of Fine Chemistry, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Korea.
Lim HN; Eco-Friendly New Materials Research Center, Therapeutics&Biotechnology Division, 141, Gajeong-ro, Yuseong-gu, Daejeon 34114, Korea.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Nov 20; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 20.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*/methods
Chemistry Techniques, Synthetic*/trends
Hydroxyquinolines/*chemical synthesis
Quinolones/*chemical synthesis
Catalysis ; Hydroxyquinolines/chemistry ; Metals/chemistry ; Molecular Structure ; Quinolones/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

Gallium(III)- and Indium(III)-Containing Ionic Liquids as Highly Active Catalysts in Organic Synthesis.

Autorzy:

Więcławik J; Department of Chemical Organic Technology and Petrochemistry, Faculty of Chemistry, Silesian University of Technology, Bolesława Krzywoustego 4, 44-100 Gliwice, Poland.
Chrobok A; Department of Chemical Organic Technology and Petrochemistry, Faculty of Chemistry, Silesian University of Technology, Bolesława Krzywoustego 4, 44-100 Gliwice, Poland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Feb 18; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 18.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Ionic Liquids*/chemistry
Gallium*
Indium ; Lewis Acids/chemistry ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis.

Autorzy:

Romashov LV; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.
Kucherov FA; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.
Kozlov KS; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.
Ananikov VP; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Photosynthesis*
Biomass ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 41.

Tytuł:

Application of Olefin Metathesis in the Synthesis of Carbo- and Heteroaromatic Compounds-Recent Advances.

Autorzy:

Rogalski S; Faculty of Chemistry, Adam Mickiewicz University, Poznań, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.
Pietraszuk C; Faculty of Chemistry, Adam Mickiewicz University, Poznań, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2023 Feb 09; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 09.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Alkenes*
Charcoal*
Cyclization ; Polyenes ; Chemistry Techniques, Synthetic

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 42.

Tytuł:

Design and Synthesis of Novel Imidazole Derivatives Possessing Triazole Pharmacophore with Potent Anticancer Activity, and In Silico ADMET with GSK-3β Molecular Docking Investigations.

Autorzy:

Al-Blewi F; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Shaikh SA; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Naqvi A; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Aljohani F; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Aouad MR; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Ihmaid S; Pharmacognosy and Pharmaceutical Chemistry Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Rezki N; Department of Chemistry, College of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Design*
Molecular Docking Simulation*
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Imidazoles/*chemistry
Imidazoles/*pharmacology
Triazoles/*chemistry
Antineoplastic Agents/chemical synthesis ; Binding Sites ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors ; Glycogen Synthase Kinase 3 beta/chemistry ; Humans ; Imidazoles/chemical synthesis ; Inhibitory Concentration 50 ; Microbial Sensitivity Tests ; Molecular Dynamics Simulation ; Molecular Structure ; Protein Binding ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 43.

Tytuł:

Synthesis, antitubercular activity and molecular docking study of substituted [1,3]dioxino[4,5- d ]pyrimidine derivatives via facile CAN catalyzed Biginelli reaction.

Autorzy:

Venkatesh T; Department of P.G. Studies and Research in Chemistry, Jnana Sahyadri, Kuvempu University Shankaraghatta, Shivamogga, Karnataka, India.
Bodke YD; Department of P.G. Studies and Research in Chemistry, Jnana Sahyadri, Kuvempu University Shankaraghatta, Shivamogga, Karnataka, India.
Manjunatha B; Department of P.G. Studies and Research in Chemistry, Jnana Sahyadri, Kuvempu University Shankaraghatta, Shivamogga, Karnataka, India.
Ravi Kumar S; Department of P.G. Studies and Research in Biotechnology, Jnana Sahyadri, Kuvempu University Shankaraghatta1, Shivamogga, Karnataka, India.

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Źródło:

Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2021; Vol. 40 (11), pp. 1037-1049. Date of Electronic Publication: 2021 Sep 02.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Antitubercular Agents/*chemistry
Antitubercular Agents/*pharmacology
Pyrimidines/*chemistry
Pyrimidines/*pharmacology
Antitubercular Agents/chemical synthesis ; Catalysis ; Drug Development/methods ; Humans ; Microbial Sensitivity Tests ; Molecular Conformation ; Molecular Structure ; Pyrimidines/chemical synthesis ; Structure-Activity Relationship

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 44.

Tytuł:

Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side Chain.

Autorzy:

Diachkov MV; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.
Ferrer K; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.
Oklestkova J; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.
Rarova L; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.
Bazgier V; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.; Department of Physical Chemistry, Faculty of Science, Palacký University Olomouc, Šlechtitelů 241/27, 77900 Olomouc, Czech Republic.
Kvasnica M; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2020 Dec 25; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 25.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Brassinosteroids/*chemical synthesis
Brassinosteroids/*pharmacology
Nitrogen/*chemistry
Arabidopsis/drug effects ; Arabidopsis/growth & development ; Brassinosteroids/chemistry ; Molecular Structure ; Plant Development/drug effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 45.

Tytuł:

A Survey of Synthetic Routes and Antitumor Activities for Benzo[ g ]quinoxaline-5,10-diones.

Autorzy:

Giuglio-Tonolo AG; Equipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Institut de Chimie Radicalaire, Aix Marseille Université, CNRS, UMR 7273, 27 Boulevard Jean Moulin, CEDEX 05, 13385 Marseille, France.
Curti C; Equipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Institut de Chimie Radicalaire, Aix Marseille Université, CNRS, UMR 7273, 27 Boulevard Jean Moulin, CEDEX 05, 13385 Marseille, France.
Terme T; Equipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Institut de Chimie Radicalaire, Aix Marseille Université, CNRS, UMR 7273, 27 Boulevard Jean Moulin, CEDEX 05, 13385 Marseille, France.
Vanelle P; Equipe Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, Institut de Chimie Radicalaire, Aix Marseille Université, CNRS, UMR 7273, 27 Boulevard Jean Moulin, CEDEX 05, 13385 Marseille, France.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 14; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 14.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Anthraquinones/*chemical synthesis
Antineoplastic Agents/*chemical synthesis
Quinoxalines/*chemical synthesis
Topoisomerase Inhibitors/*chemical synthesis
Anthraquinones/pharmacology ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Inhibitory Concentration 50 ; Neoplasms/drug therapy ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Quinoxalines/pharmacology ; Structure-Activity Relationship ; Topoisomerase Inhibitors/pharmacology ; Tumor Suppressor Protein p53/agonists ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 46.

Tytuł:

Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles.

Autorzy:

Banik BK; Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Deanship of Research Development, Prince Mohammad Bin Fahd University, Al Khobar 31952, Saudi Arabia.
Banerjee B; Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh 174301, India.
Kaur G; Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh 174301, India.
Saroch S; Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh 174301, India.
Kumar R; Department of Chemistry, Indus International University, V.P.O. Bathu, Distt. Una, Himachal Pradesh 174301, India.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 14; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 14.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Biological Products/*chemical synthesis
Heterocyclic Compounds/*chemical synthesis
Quaternary Ammonium Compounds/*chemistry
Alkylation ; Biological Products/classification ; Catalysis ; Esterification ; Heterocyclic Compounds/classification ; Humans ; Oxidation-Reduction ; Solvents

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 47.

Tytuł:

Recent Advances on Synthetic Methodology Merging C-H Functionalization and C-C Cleavage.

Autorzy:

Azizollahi H; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 91775-1436, Iran.
García-López JA; Grupo de Química Organometálica, Campus de Espinardo, Universidad de Murcia, 30100 Murcia, Spain.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 13; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 13.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Carbon/*chemistry
Hydrogen/*chemistry
Catalysis ; Chemical Phenomena ; Hydrolysis ; Molecular Structure

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 48.

Tytuł:

Synthetic Methods of Phosphonopeptides.

Autorzy:

Xu J; State Key Laboratory of Chemical Resource Engineering, Department of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 12; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 12.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Chemistry Techniques, Synthetic*
Peptides/*chemical synthesis
Phosphoproteins/*chemical synthesis
Chlorides/chemistry ; Halogenation ; Organophosphorus Compounds/chemistry ; Oxalates/chemistry ; Peptides/chemistry ; Phosphoproteins/chemistry

Czasopismo naukowe

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Skocz do pozycji: 49.

Tytuł:

Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,2'-indoline]-1,3,8-trione Derivatives against the MCF-7 Cancer Cell Line.

Autorzy:

Gobinath P; Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanamapatti, Tamilnadu 621007, India.
Packialakshmi P; Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanamapatti, Tamilnadu 621007, India.
Daoud A; Department of Zoology, College of Sciences, King Saud University (KSU), P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Alarifi S; Department of Zoology, College of Sciences, King Saud University (KSU), P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Idhayadhulla A; Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanamapatti, Tamilnadu 621007, India.
Radhakrishnan S; Department of Chemistry, Nehru Memorial College, Affiliated Bharathidasan University, Puthanamapatti, Tamilnadu 621007, India.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 11; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 11.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Drug Screening Assays, Antitumor*
Antineoplastic Agents/*pharmacology
Spiro Compounds/*pharmacology
Benzenesulfonates/chemistry ; Catalysis ; Combinatorial Chemistry Techniques ; Drug Design ; Humans ; MCF-7 Cells ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Molecular Structure ; Solvents ; Spectroscopy, Fourier Transform Infrared ; Spiro Compounds/chemistry

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 50.

Tytuł:

Exploring Free Energy Profiles of Enantioselective Organocatalytic Aldol Reactions under Full Solvent Influence.

Autorzy:

Weiß M; Institut für Chemie, Martin-Luther-Universität Halle-Wittenberg, von-Danckelmann-Platz 4, D-06120 Halle (Saale), Germany.
Brehm M; Institut für Chemie, Martin-Luther-Universität Halle-Wittenberg, von-Danckelmann-Platz 4, D-06120 Halle (Saale), Germany.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2020 Dec 11; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 11.

Typ publikacji:

Journal Article

MeSH Terms:

Chemistry Techniques, Synthetic*
Aldehydes/*chemistry
Solvents/*chemistry
Catalysis ; Computer Simulation ; Entropy ; Molecular Dynamics Simulation ; Organic Chemicals ; Proline/chemistry ; Software ; Stereoisomerism ; Temperature ; Thermodynamics ; Water/chemistry

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły