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Wyszukujesz frazę ""Chemokine CCL2"" wg kryterium: Temat


Tytuł :
ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling.
Autorzy :
Akhter N; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Wilson A; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Thomas R; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Al-Rashed F; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Kochumon S; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Al-Roub A; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Arefanian H; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Al-Madhoun A; Department of Genetics & Bioinformatics, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.; Animal & Imaging Core Facility, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Al-Mulla F; Department of Genetics & Bioinformatics, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Ahmad R; Department of Immunology & Microbiology, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Sindhu S; Animal & Imaging Core Facility, Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 29; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2/*genetics
Extracellular Signal-Regulated MAP Kinases/*metabolism
Hydrogen Peroxide/*pharmacology
Interleukin-8/*genetics
Monocytes/*drug effects
NF-kappa B/*metabolism
Tumor Necrosis Factor-alpha/*pharmacology
Adipose Tissue/metabolism ; Adult ; Aged ; Aged, 80 and over ; Chemokine CCL2/metabolism ; Female ; Gene Expression/drug effects ; Humans ; Interleukin-8/metabolism ; Male ; Middle Aged ; Monocytes/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways.
Autorzy :
Liu F; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Liu X; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.
Zhou Y; The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yu Y; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.; The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, China.
Wang K; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.
Zhou Z; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.
Gao H; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, China.
So KF; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.; Key Laboratory of CNS Regeneration (Jinan University), Ministry of Education, China.; Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
Vardi N; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.
Xu Y; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.; Key Laboratory of CNS Regeneration (Jinan University), Ministry of Education, China.; Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 Sep; Vol. 158 (5), pp. 1131-1150. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lycium*
Chemokine CCL2/*antagonists & inhibitors
MAP Kinase Signaling System/*drug effects
Palmitates/*therapeutic use
Retinal Degeneration/*prevention & control
Retinitis Pigmentosa/*prevention & control
STAT3 Transcription Factor/*antagonists & inhibitors
Xanthophylls/*therapeutic use
Animals ; Chemokine CCL2/metabolism ; Female ; MAP Kinase Signaling System/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Palmitates/isolation & purification ; Palmitates/pharmacology ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Retinitis Pigmentosa/metabolism ; Retinitis Pigmentosa/pathology ; STAT3 Transcription Factor/metabolism ; Xanthophylls/isolation & purification ; Xanthophylls/pharmacology
Czasopismo naukowe
Tytuł :
[RS102895 inhibits the proliferation, invasion, and migration of PC-3 prostate cancer cells by blocking CCL2/CCR2 pathway].
Autorzy :
Wang J; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Chen K; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Li X; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Yang B; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Pang H; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Wang C; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China.
Zhang J; Key laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi 832000, China. *Corresponding author, E-mail: .
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Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2021 Sep; Vol. 37 (9), pp. 781-787.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2*/genetics
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Humans ; Male ; Matrix Metalloproteinase 2/genetics ; Neoplasm Invasiveness ; PC-3 Cells ; Receptors, CCR2/genetics ; Receptors, Chemokine
Czasopismo naukowe
Tytuł :
HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages.
Autorzy :
Song X; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Gao X; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Wang Y; Department of Infectious Diseases, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Raja R; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.
Zhang Y; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Yang S; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Li M; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Yao Z; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Wei L; Department of Immunology, Hebei Medical University, Shijiazhuang, China.; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Aug 31; Vol. 12, pp. 654998. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CCL2/*immunology
Chemokine CXCL10/*immunology
Hepacivirus/*immunology
Macrophages/*immunology
NF-kappa B/*immunology
Signal Transduction/*immunology
Viral Core Proteins/*immunology
Animals ; Cells, Cultured ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Chemokine CXCL10/genetics ; Chemokine CXCL10/metabolism ; Gene Expression/immunology ; Hepacivirus/metabolism ; Hepacivirus/physiology ; Hepatitis C/immunology ; Hepatitis C/metabolism ; Hepatitis C/virology ; Host-Pathogen Interactions/immunology ; Humans ; Kupffer Cells/immunology ; Kupffer Cells/metabolism ; Kupffer Cells/virology ; Macrophages/metabolism ; Macrophages/virology ; Mice ; Mice, Inbred BALB C ; RAW 264.7 Cells ; THP-1 Cells ; Viral Core Proteins/metabolism
Czasopismo naukowe
Tytuł :
IL-6 deficiency promotes colitis by recruiting Ly6C monocytes into inflamed colon tissues in a CCL2-CCR2-dependent manner.
Autorzy :
Cao Q; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Lin Y; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Yue C; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Wang Y; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Quan F; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Cui X; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Bi R; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Tang X; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China.
Yang Y; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China; School of Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, Jiangsu, 221004, China.
Wang C; State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China. Electronic address: .
Li X; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China. Electronic address: .
Gao X; Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Aug 05; Vol. 904, pp. 174165. Date of Electronic Publication: 2021 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Ly/*immunology
Chemokine CCL2/*immunology
Colitis, Ulcerative/*genetics
Colon/*immunology
Interleukin-6/*deficiency
Monocytes/*immunology
Receptors, CCR2/*immunology
Animals ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/immunology ; Colitis, Ulcerative/pathology ; Colon/drug effects ; Colon/metabolism ; Dextran Sulfate/toxicity ; Disease Models, Animal ; Gastrointestinal Microbiome/genetics ; Gastrointestinal Microbiome/immunology ; Gene Knockout Techniques ; Inflammation/genetics ; Inflammation/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology ; Macrophages/immunology ; Male ; Mice ; Mice, Knockout ; Neutrophils/immunology ; Receptors, CCR2/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Involvement of chronic inflammation via monocyte chemoattractant protein-1 in uraemic cardiomyopathy: a human biopsy study.
Autorzy :
Nakano T; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.; Department of Internal Medicine, Yamato-Takada Municipal Hospital, Yamato-Takada, Nara, Japan.
Onoue K; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Seno A; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Ishihara S; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Nakada Y; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Nakagawa H; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Ueda T; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Nishida T; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Soeda T; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Watanabe M; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Kawakami R; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Hatakeyama K; Department of Pathology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.; Department of Diagnostic Pathology, Nara Medical University, Kashihara, Nara, Japan.
Sakaguchi Y; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
Ohbayashi C; Department of Diagnostic Pathology, Nara Medical University, Kashihara, Nara, Japan.
Saito Y; Department of Cardiovascular Medicine, Nara Medical University, Kashihara, Nara, Japan.
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Źródło :
ESC heart failure [ESC Heart Fail] 2021 Aug; Vol. 8 (4), pp. 3156-3167. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiomyopathies*/diagnosis
Cardiomyopathies*/etiology
Chemokine CCL2*
Adult ; Aged ; Biopsy ; Female ; Humans ; Inflammation ; Middle Aged ; Placenta Growth Factor ; Stroke Volume ; Ventricular Function, Left
Czasopismo naukowe
Tytuł :
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration.
Autorzy :
Kong XY; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Huse C; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Yang K; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Øgaard J; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Berges N; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Vik ES; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Nawaz MS; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Quiles-Jiménez A; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Abbas A; Ostfold Hospital Trust Kalnes Norway.
Gregersen I; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Holm S; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Bjerkli V; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Rashidi A; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Fladeby C; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Suganthan R; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Sagen EL; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.
Skjelland M; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Department of Neurology Oslo University Hospital, Rikshospitalet Oslo Norway.
Lång A; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Bøe SO; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Bjørås M; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.; Department of Clinical and Molecular Medicine Norwegian University of Science and Technology Trondheim Norway.
Aukrust P; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.; Section of Clinical Immunology and Infectious Diseases Oslo University Hospital, Rikshospitalet Oslo Norway.; K.G. Jebsen, The Faculty of Health Sciences The Arctic University of Tromsø Tromsø Norway.
Alseth I; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
Halvorsen B; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Institute of Clinical Medicine Faculty of Medicine University of Oslo Norway.
Dahl TB; Research Institute for Internal Medicine Oslo University Hospital, Rikshospitalet Oslo Norway.; Department of Microbiology Oslo University Hospital, Rikshospitalet Oslo Norway.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2021 Jul 20; Vol. 10 (14), pp. e020656. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Aorta, Thoracic/*pathology
Atherosclerosis/*genetics
Chemokine CCL2/*genetics
Deoxyribonuclease (Pyrimidine Dimer)/*genetics
Monocytes/*metabolism
RNA/*genetics
Aged ; Animals ; Aorta, Thoracic/metabolism ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Chemokine CCL2/biosynthesis ; Cytokines ; Deoxyribonuclease (Pyrimidine Dimer)/biosynthesis ; Disease Models, Animal ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/pathology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Short Chain Fatty Acid Acetate Increases TNFα-Induced MCP-1 Production in Monocytic Cells via ACSL1/MAPK/NF-κB Axis.
Autorzy :
Al-Roub A; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Akhter N; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Al-Sayyar A; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Wilson A; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Thomas R; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Kochumon S; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Al-Rashed F; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Al-Mulla F; Genetics & Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Sindhu S; Animal and Imaging Core Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Ahmad R; Immunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article
MeSH Terms :
Acetates/*pharmacology
Chemokine CCL2/*biosynthesis
Fatty Acids, Volatile/*pharmacology
Monocytes/*drug effects
Monocytes/*metabolism
Acetates/administration & dosage ; Chemokine CCL2/genetics ; Coenzyme A Ligases/antagonists & inhibitors ; Coenzyme A Ligases/metabolism ; Drug Synergism ; Enzyme Inhibitors/pharmacology ; Fatty Acids, Volatile/administration & dosage ; Humans ; MAP Kinase Signaling System ; Models, Biological ; Monocytes/immunology ; NF-kappa B/metabolism ; Obesity/etiology ; Obesity/metabolism ; Phosphorylation ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; THP-1 Cells ; Triazenes/pharmacology ; Tumor Necrosis Factor-alpha/administration & dosage ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
EGR1 and RXRA transcription factors link TGF-β pathway and CCL2 expression in triple negative breast cancer cells.
Autorzy :
Gorbacheva AM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Uvarova AN; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Ustiugova AS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Bhattacharyya A; Immunology Laboratory, Department of Zoology, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Korneev KV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Kuprash DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Biological Faculty, Lomonosov Moscow State University, Moscow, 119234, Russia.
Mitkin NA; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jul 08; Vol. 11 (1), pp. 14120. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Chemokine CCL2/*metabolism
Early Growth Response Protein 1/*metabolism
Retinoid X Receptor alpha/*metabolism
Transforming Growth Factor beta/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Base Sequence ; Binding Sites ; Cell Line, Tumor ; Chemokine CCL2/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Models, Biological ; Point Mutation/genetics ; Promoter Regions, Genetic/genetics ; Protein Binding ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Gamma-glutamyl carboxylated Gas6 facilitates the prophylactic effect of vitamin K in inhibiting hyperlipidemia-associated inflammatory pathophysiology via arresting MCP-1/ICAM-1 mediated monocyte-hepatocyte adhesion.
Autorzy :
Bordoloi J; Biotechnology Group, Biological Science and Technology Division, CSIR-North East Institute of Science and Technology (CSIR-NEIST), Jorhat, Assam, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Ozah D; Clinical Centre, CSIR-North East Institute of Science and Technology, Jorhat, Assam, India.
Bora T; Clinical Centre, CSIR-North East Institute of Science and Technology, Jorhat, Assam, India.
Kalita J; Research Planning and Business Development Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India. Electronic address: .
Manna P; Biotechnology Group, Biological Science and Technology Division, CSIR-North East Institute of Science and Technology (CSIR-NEIST), Jorhat, Assam, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India. Electronic address: .
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2021 Jul; Vol. 93, pp. 108635. Date of Electronic Publication: 2021 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CCL2/*metabolism
Hyperlipidemias/*complications
Inflammation/*drug therapy
Intercellular Adhesion Molecule-1/*metabolism
Intercellular Signaling Peptides and Proteins/*metabolism
Vitamin K/*pharmacology
Cell Adhesion/drug effects ; Cell Adhesion/physiology ; Chemokine CCL2/genetics ; Chronic Disease ; Gene Expression Regulation/drug effects ; Hepatocytes/physiology ; Humans ; Inflammation/etiology ; Intercellular Adhesion Molecule-1/genetics ; Intercellular Signaling Peptides and Proteins/genetics ; Monocytes/physiology
Czasopismo naukowe
Tytuł :
On the Role of Paraoxonase-1 and Chemokine Ligand 2 (C-C motif) in Metabolic Alterations Linked to Inflammation and Disease. A 2021 Update.
Autorzy :
Camps J; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Castañé H; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Rodríguez-Tomàs E; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.; Department of Radiation Oncology, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Baiges-Gaya G; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Hernández-Aguilera A; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Arenas M; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.; Department of Radiation Oncology, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Iftimie S; Department of Internal Medicine, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
Joven J; Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain.
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Źródło :
Biomolecules [Biomolecules] 2021 Jul 01; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Aryldialkylphosphatase/*metabolism
Chemokine CCL2/*metabolism
Metabolic Diseases/*metabolism
Aryldialkylphosphatase/physiology ; Chemokine CCL2/physiology ; Homeostasis ; Humans ; Inflammation ; Ligands ; Lipoproteins, HDL/metabolism ; Lipoproteins, LDL/metabolism ; Metabolic Diseases/immunology ; Metabolic Diseases/physiopathology ; Oxidation-Reduction ; Oxidative Stress
Czasopismo naukowe
Tytuł :
Photobiomodulation Promotes Neuronal Axon Regeneration After Oxidative Stress and Induces a Change in Polarization from M1 to M2 in Macrophages via Stimulation of CCL2 in Neurons: Relevance to Spinal Cord Injury.
Autorzy :
Zheng Q; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Zhang J; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Zuo X; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Sun J; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Liang Z; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Hu X; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China. .
Wang Z; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China. .
Li K; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Song J; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Ding T; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Shen X; Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Ma Y; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Li P; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
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Źródło :
Journal of molecular neuroscience : MN [J Mol Neurosci] 2021 Jun; Vol. 71 (6), pp. 1290-1300. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Oxidative Stress*
Spinal Cord Regeneration*
Axons/*metabolism
Chemokine CCL2/*metabolism
Macrophages/*cytology
Phototherapy/*methods
Spinal Cord Injuries/*therapy
Animals ; Axons/radiation effects ; Cell Differentiation ; Cells, Cultured ; Chemokine CCL2/genetics ; Female ; Ganglia, Spinal/cytology ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/physiology ; Interleukin-1beta/metabolism ; Light ; Macrophages/immunology ; Macrophages/radiation effects ; Male ; Mice ; Mice, Inbred BALB C ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Acteoside Presents Protective Effects on Cerebral Ischemia/reperfusion Injury Through Targeting CCL2, CXCL10, and ICAM1.
Autorzy :
Wu W; Department of Neurosurgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, PR China.
Wu G; Department of Neurology, Binzhou People's Hospital, Binzhou, Shandong Province, PR China.
Cao D; The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, PR China. .
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Źródło :
Cell biochemistry and biophysics [Cell Biochem Biophys] 2021 Jun; Vol. 79 (2), pp. 301-310. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2/*metabolism
Chemokine CXCL10/*metabolism
Glucosides/*pharmacology
Intercellular Adhesion Molecule-1/*metabolism
Phenols/*pharmacology
Up-Regulation/*drug effects
Animals ; Apoptosis/drug effects ; Cell Hypoxia ; Cell Line ; Cell Proliferation/drug effects ; Chemokine CCL2/genetics ; Chemokine CXCL10/genetics ; Intercellular Adhesion Molecule-1/genetics ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Oxygen/metabolism ; Oxygen/pharmacology ; Protective Agents/pharmacology ; Rats ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Potential Role of Macrophage Phenotypes and CCL2 in the Pathogenesis of Takayasu Arteritis.
Autorzy :
Kong X; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xu M; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Organ Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China.
Cui X; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ma L; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Cheng H; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Hou J; Department of Cardiac Surgery, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Sun X; Department of Cardiac Surgery, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Ma L; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiang L; Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China.; Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 17; Vol. 12, pp. 646516. Date of Electronic Publication: 2021 May 17 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers/*blood
Chemokine CCL2/*immunology
Macrophages/*immunology
Takayasu Arteritis/*immunology
Blood Sedimentation ; C-Reactive Protein/metabolism ; Chemokine CCL2/blood ; Chemokine CCL2/metabolism ; Disease Progression ; Female ; Humans ; Interleukin-6/blood ; Macrophages/classification ; Male ; Phenotype ; Takayasu Arteritis/pathology ; Takayasu Arteritis/therapy
Czasopismo naukowe
Tytuł :
Loss of Speckle-Type POZ Protein Promotes Prostate Cancer Cell Migration and Invasion Through Upregulation of MCP-1.
Autorzy :
Shi J; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Cao J; Department of Experimental Pathology, Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China (mainland).
Lu X; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Fan L; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Guo H; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
Fu J; Key Laboratory of Longevity and Aging-Related Disease of the Chinese Ministry of Education, Guangxi Medical University, Nanning, Guangxi, China (mainland).; Center for Translational Medicine and School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2021 Apr 19; Vol. 27, pp. e929199. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Chemokine CCL2/*metabolism
Nuclear Proteins/*metabolism
Prostatic Neoplasms/*metabolism
Repressor Proteins/*metabolism
Antibodies, Blocking/metabolism ; Cell Movement ; Cell Proliferation ; Chemokine CCL2/genetics ; Chemokine CCL2/immunology ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Male ; Mutation/genetics ; Neoplasm Invasiveness ; Nuclear Proteins/genetics ; Prostatic Neoplasms/pathology ; Repressor Proteins/genetics ; Tumor Cells, Cultured ; Up-Regulation ; Wound Healing/genetics
Czasopismo naukowe
Tytuł :
MiR-154-5p-MCP1 Axis Regulates Allergic Inflammation by Mediating Cellular Interactions.
Autorzy :
Kim M; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Jo H; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Kwon Y; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Jeong MS; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon, South Korea.
Jung HS; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Kim Y; Institute of New Frontier Research, College of Medicine, Hallym University, Chuncheon, South Korea.
Jeoung D; Department of Biochemistry, Kangwon National University, Chuncheon, South Korea.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 31; Vol. 12, pp. 663726. Date of Electronic Publication: 2021 May 31 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Communication*/genetics
Cell Communication*/immunology
Gene Expression Regulation*
RNA Interference*
Chemokine CCL2/*genetics
Hypersensitivity/*etiology
MicroRNAs/*genetics
Anaphylaxis/genetics ; Anaphylaxis/metabolism ; Anaphylaxis/pathology ; Animals ; Antigens/immunology ; Chemokine CCL2/metabolism ; Disease Models, Animal ; Exosomes/metabolism ; Female ; Hypersensitivity/metabolism ; Hypersensitivity/pathology ; Mice ; Skin/immunology ; Skin/metabolism ; Skin/pathology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Effect of miR-506-3p on Proliferation and Apoptosis of Airway Smooth Muscle Cells in Asthmatic Mice by Regulating CCL2 Gene Expression and Mediating TLR4/NF-κB Signaling Pathway Activation.
Autorzy :
Manli W; Department 1 of Respiratory and Critical Care Medicine, Nanyang First People's Hospital, No. 12, Renmin Road, Nanyang City, 473000, Hubei, People's Republic of China. .
Hua Q; Department 1 of Respiratory and Critical Care Medicine, Nanyang First People's Hospital, No. 12, Renmin Road, Nanyang City, 473000, Hubei, People's Republic of China.
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Źródło :
Molecular biotechnology [Mol Biotechnol] 2021 May; Vol. 63 (5), pp. 410-423. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*genetics
Asthma/*genetics
Chemokine CCL2/*genetics
Lung/*pathology
MicroRNAs/*metabolism
Myocytes, Smooth Muscle/*metabolism
NF-kappa B/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; Asthma/pathology ; Base Sequence ; Cell Cycle/genetics ; Cell Proliferation/genetics ; Chemokine CCL2/metabolism ; Gene Expression Regulation ; Mice, Inbred BALB C ; MicroRNAs/genetics ; Plasmids/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
CC chemokine ligand 2 (CCL2) stimulates aromatase gene expression in mammary adipose tissue.
Autorzy :
Martínez-Chacón G; Functional Foods Forum, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.
Yatkin E; Functional Foods Forum, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.; Central Animal Laboratory, University of Turku, Turku, Finland.
Polari L; Functional Foods Forum, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.; Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, Turku, Finland.
Deniz Dinç D; Institute of Biomedicine, University of Turku, Turku, Finland.; FICAN West Cancer Research Laboratory, University of Turku and Turku University Hospital, Turku, Finland.; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Peuhu E; Institute of Biomedicine, University of Turku, Turku, Finland.; FICAN West Cancer Research Laboratory, University of Turku and Turku University Hospital, Turku, Finland.; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Hartiala P; Institute of Biomedicine, University of Turku, Turku, Finland.; Department of Plastic and General Surgery, Turku University Hospital (TYS), Turku, Finland.
Saarinen N; Functional Foods Forum, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.; Turku Center for Disease Modeling, University of Turku, Turku, Finland.
Mäkelä S; Functional Foods Forum, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.; Turku Center for Disease Modeling, University of Turku, Turku, Finland.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21536.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Enzymologic*
Transcriptional Activation*
Aromatase/*metabolism
Breast/*metabolism
Chemokine CCL2/*metabolism
Mesenchymal Stem Cells/*metabolism
Obesity/*physiopathology
Animals ; Aromatase/genetics ; Breast/cytology ; Chemokine CCL2/genetics ; Female ; Humans ; Mesenchymal Stem Cells/cytology ; Mice
Czasopismo naukowe
Tytuł :
Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer.
Autorzy :
Liu Y; Division of Pharmacoengineering and Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. .
Tiruthani K
Wang M
Zhou X
Qiu N
Xiong Y
Pecot CV
Liu R
Huang L
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Źródło :
Nanoscale horizons [Nanoscale Horiz] 2021 Apr 01; Vol. 6 (4), pp. 319-329. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes/*metabolism
Chemokine CCL2/*metabolism
Drug Carriers/*chemistry
Nanoparticles/*chemistry
Triple Negative Breast Neoplasms/*therapy
Tumor Microenvironment/*immunology
Animals ; Cell Line, Tumor ; Chemokine CCL2/immunology ; DNA/genetics ; Female ; Genetic Therapy ; Immunotherapy ; Lipids/chemistry ; Mice, Inbred BALB C ; Plasmids ; Single-Domain Antibodies/genetics ; Single-Domain Antibodies/immunology ; Single-Domain Antibodies/therapeutic use
Czasopismo naukowe
Tytuł :
The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.
Autorzy :
Huang Z; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden.
Liang N; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden.
Goñi S; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden.
Damdimopoulos A; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden.
Wang C; Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Ballaire R; Inovarion, 75005 Paris, France.
Jager J; Department of Medicine, Integrated Cardio Metabolic Centre (ICMC), Karolinska Institutet, 14152 Huddinge, Sweden.
Niskanen H; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, PO Box 1627, 70211 Kuopio, Finland.
Han H; Department of Medicine, Centre for Hematology and Regenerative Medicine (HERM), Karolinska Institutet, 14183 Huddinge, Sweden.
Jakobsson T; Department of Laboratory Medicine, Karolinska Institutet, Division of Clinical Chemistry, Karolinska University Hospital, 14186 Huddinge, Sweden.
Bracken AP; Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Aouadi M; Department of Medicine, Integrated Cardio Metabolic Centre (ICMC), Karolinska Institutet, 14152 Huddinge, Sweden; Department of Medicine, Centre for Infectious Medicine (CIM), Karolinska Institutet, 14152 Huddinge, Sweden.
Venteclef N; Centre de Recherche des Cordeliers, INSERM, Université de Paris, Sorbonne Université, IMMEDIAB Laboratory, 75006 Paris, France.
Kaikkonen MU; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, PO Box 1627, 70211 Kuopio, Finland.
Fan R; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden. Electronic address: .
Treuter E; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Sweden. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Mar 04; Vol. 81 (5), pp. 953-968.e9. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Silencer Elements, Transcriptional*
Chemokine CCL2/*genetics
Co-Repressor Proteins/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Nuclear Receptor Co-Repressor 2/*genetics
Obesity/*genetics
Adipose Tissue/immunology ; Adipose Tissue/pathology ; Animals ; CRISPR-Cas Systems ; Chemokine CCL2/immunology ; Co-Repressor Proteins/immunology ; Gene Editing ; Gene Expression Regulation/drug effects ; HEK293 Cells ; Histone Acetyltransferases/genetics ; Histone Acetyltransferases/immunology ; Histones/genetics ; Histones/immunology ; Humans ; Intracellular Signaling Peptides and Proteins/immunology ; Lipopolysaccharides/pharmacology ; Macrophage Activation/drug effects ; Male ; Mediator Complex Subunit 1/genetics ; Mediator Complex Subunit 1/immunology ; Mice ; Mice, Obese ; Nuclear Receptor Co-Repressor 2/immunology ; Obesity/immunology ; Obesity/pathology ; RAW 264.7 Cells ; RNA, Untranslated/genetics ; RNA, Untranslated/immunology ; Signal Transduction
Czasopismo naukowe

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