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Wyszukujesz frazę ""Chemokine CXCL9"" wg kryterium: Temat


Tytuł :
CXCL9 Regulates TGF-β1-Induced Epithelial to Mesenchymal Transition in Human Alveolar Epithelial Cells.
Autorzy :
O'Beirne SL; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Walsh SM; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Fabre A; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland;
Reviriego C; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Worrell JC; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Counihan IP; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Lumsden RV; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Cramton-Barnes J; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Belperio JA; Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095; and.
Donnelly SC; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Boylan D; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Marchal-Sommé J; INSERM Unité Mixte de Recherche 700, Physiopathologie et Epidémiologie de l'Insuffisance Respiratoire, Universite Denis Diderot, Paris 7, Unité de Formation et de Recherche de Médecine, 75018 Paris, France.
Kane R; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland;
Keane MP; St. Vincent's University Hospital and School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Sep 15; Vol. 195 (6), pp. 2788-96. Date of Electronic Publication: 2015 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CXCL9/*metabolism
Epithelial-Mesenchymal Transition/*physiology
Idiopathic Pulmonary Fibrosis/*pathology
Respiratory Mucosa/*metabolism
Transforming Growth Factor beta1/*metabolism
Actins/biosynthesis ; Biomarkers/metabolism ; Cell Line ; Chemokine CXCL9/pharmacology ; Epithelial Cells/metabolism ; Humans ; Nuclear Proteins/biosynthesis ; Phosphorylation ; Pulmonary Alveoli/cytology ; Pulmonary Alveoli/metabolism ; Receptors, CXCR3/biosynthesis ; Receptors, CXCR3/metabolism ; Respiratory Mucosa/cytology ; Smad2 Protein/biosynthesis ; Smad3 Protein/biosynthesis ; Smad7 Protein/biosynthesis ; Thyroid Nuclear Factor 1 ; Transcription Factors/biosynthesis ; Transforming Growth Factor beta1/pharmacology
Czasopismo naukowe
Tytuł :
CXCR3/CXCL10 Axis Shapes Tissue Distribution of Memory Phenotype CD8 T Cells in Nonimmunized Mice.
Autorzy :
Alanio C; Laboratory of Dendritic Cell Immunology, Institut Pasteur, 75015 Paris, France.; Inserm U1223, 75015 Paris, France.; Center for Translational Research, Institut Pasteur, 75015 Paris, France.
Barreira da Silva R; Department of Cancer Immunology, Genentech, South San Francisco, CA 94080; and.
Michonneau D; Inserm U1223, 75015 Paris, France.; Laboratory of Dynamics of Immune Responses, Institut Pasteur, 75015 Paris, France.
Bousso P; Inserm U1223, 75015 Paris, France.; Laboratory of Dynamics of Immune Responses, Institut Pasteur, 75015 Paris, France.
Ingersoll MA; Laboratory of Dendritic Cell Immunology, Institut Pasteur, 75015 Paris, France.; Inserm U1223, 75015 Paris, France.
Albert ML; Laboratory of Dendritic Cell Immunology, Institut Pasteur, 75015 Paris, France; .; Inserm U1223, 75015 Paris, France.; Department of Cancer Immunology, Genentech, South San Francisco, CA 94080; and.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2018 Jan 01; Vol. 200 (1), pp. 139-146. Date of Electronic Publication: 2017 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Chemokine CXCL10/*metabolism
Receptors, CXCR3/*metabolism
Animals ; Cells, Cultured ; Chemokine CXCL10/genetics ; Chemokine CXCL9/genetics ; Chemokine CXCL9/metabolism ; Immunologic Memory ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phenotype ; Receptors, Antigen, T-Cell/metabolism ; Receptors, CXCR3/genetics
Czasopismo naukowe
Tytuł :
Cutaneous tumors cease CXCL9/Mig production as a result of IFN-γ-mediated immunoediting.
Autorzy :
Petro M; Department of Immunology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Kish D
Guryanova OA
Ilyinskaya G
Kondratova A
Fairchild RL
Gorbachev AV
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Jan 15; Vol. 190 (2), pp. 832-41. Date of Electronic Publication: 2012 Dec 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CXCL9/*metabolism
Interferon-gamma/*pharmacology
Skin Neoplasms/*immunology
Animals ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/immunology ; Chemokine CXCL9/deficiency ; Chemokine CXCL9/genetics ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Interferon-gamma/genetics ; Melanoma, Experimental/genetics ; Melanoma, Experimental/immunology ; Mice ; Mice, Knockout ; Skin Neoplasms/genetics
Czasopismo naukowe
Tytuł :
CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
Autorzy :
Giegold O; Pharmazentrum Frankfurt/Zentrum für Arzneimittelforschung, -Entwicklung und -Sicherheit, Klinikum der Johann Wolfgang Goethe Universität Frankfurt, D-60590 Frankfurt am Main, Germany. />Ogrissek N
Richter C
Schröder M
Herrero San Juan M
Pfeilschifter JM
Radeke HH
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Apr 01; Vol. 190 (7), pp. 3696-705. Date of Electronic Publication: 2013 Feb 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunologic Memory*
Chemokine CXCL12/*metabolism
Chemokine CXCL9/*metabolism
Lymphocyte Activation/*immunology
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Animals ; Calcium/metabolism ; Chemokine CXCL12/pharmacology ; Chemokine CXCL9/pharmacology ; Chemotaxis/drug effects ; Chemotaxis/immunology ; Humans ; Lymphocyte Activation/drug effects ; Mice ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, CXCR3/metabolism ; Receptors, CXCR4/metabolism ; T-Lymphocytes/drug effects ; Th1 Cells/drug effects ; Th1 Cells/immunology ; Transendothelial and Transepithelial Migration/drug effects ; Transendothelial and Transepithelial Migration/immunology ; rac GTP-Binding Proteins/antagonists & inhibitors ; rac GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Staphylococcus aureus Downregulates IP-10 Production and Prevents Th1 Cell Recruitment.
Autorzy :
Li Z; Microbiome and Disease Tolerance Centre, Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3A 2B4, Canada; and.
Levast B; Microbiome and Disease Tolerance Centre, Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3A 2B4, Canada; and.
Madrenas J; Microbiome and Disease Tolerance Centre, Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3A 2B4, Canada; and .; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90277.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Mar 01; Vol. 198 (5), pp. 1865-1874. Date of Electronic Publication: 2017 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
Antigens, Bacterial/*immunology
Chemokine CXCL10/*biosynthesis
Staphylococcus aureus/*immunology
Superantigens/*immunology
Th1 Cells/*immunology
Chemokine CXCL10/genetics ; Chemokine CXCL10/immunology ; Chemokine CXCL11/immunology ; Chemokine CXCL9/genetics ; Chemokine CXCL9/immunology ; Down-Regulation ; Humans ; MAP Kinase Signaling System ; STAT1 Transcription Factor/metabolism ; Staphylococcal Infections/immunology
Czasopismo naukowe
Tytuł :
Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway.
Autorzy :
Huang W; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Hu K
Luo S
Zhang M
Li C
Jin W
Liu Y
Griffin GE
Shattock RJ
Hu Q
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2012 Jun 15; Vol. 188 (12), pp. 6247-57. Date of Electronic Publication: 2012 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD4-Positive T-Lymphocytes/*metabolism
Chemokine CXCL9/*biosynthesis
Epithelial Cells/*virology
Herpes Simplex/*metabolism
MAP Kinase Signaling System/*immunology
Adult ; Blotting, Western ; CCAAT-Enhancer-Binding Protein-beta/immunology ; CD4-Positive T-Lymphocytes/immunology ; Cervix Uteri/virology ; Chemokine CXCL9/genetics ; Chemotaxis, Leukocyte/genetics ; Chemotaxis, Leukocyte/immunology ; Chromatin Immunoprecipitation ; Electrophoretic Mobility Shift Assay ; Enzyme-Linked Immunosorbent Assay ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Female ; Gene Expression Regulation/genetics ; Gene Expression Regulation/immunology ; Herpes Simplex/immunology ; Herpesvirus 2, Human/immunology ; Humans ; Middle Aged ; Promoter Regions, Genetic/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Transfection ; Young Adult
Czasopismo naukowe
Tytuł :
FLI1 Levels Impact CXCR3 Expression and Renal Infiltration of T Cells and Renal Glycosphingolipid Metabolism in the MRL/lpr Lupus Mouse Strain.
Autorzy :
Sundararaj KP; Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425;
Thiyagarajan T; Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425;
Molano I; Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425;
Basher F; Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425; and.
Powers TW; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC 29425.
Drake RR; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC 29425.
Nowling TK; Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Dec 15; Vol. 195 (12), pp. 5551-60. Date of Electronic Publication: 2015 Nov 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Glycosphingolipids/*metabolism
Kidney/*physiology
Nephritis/*drug therapy
Proto-Oncogene Protein c-fli-1/*metabolism
Receptors, CXCR3/*metabolism
T-Lymphocyte Subsets/*immunology
T-Lymphocytes/*immunology
Animals ; Antigens, CD/metabolism ; Cell Movement/drug effects ; Chemokine CXCL10/genetics ; Chemokine CXCL10/metabolism ; Chemokine CXCL9/genetics ; Chemokine CXCL9/metabolism ; Gene Expression Regulation ; Humans ; Kidney/drug effects ; Lactosylceramides/metabolism ; Mice ; Mice, Inbred MRL lpr ; Mice, Knockout ; Nephritis/immunology ; Neuraminidase/metabolism ; Proto-Oncogene Protein c-fli-1/genetics ; Receptors, CXCR3/genetics
Czasopismo naukowe
Tytuł :
CXC chemokine ligand (CXCL) 9 and CXCL10 are antagonistic costimulation molecules during the priming of alloreactive T cell effectors.
Autorzy :
Rosenblum JM; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA. />Shimoda N
Schenk AD
Zhang H
Kish DD
Keslar K
Farber JM
Fairchild RL
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2010 Apr 01; Vol. 184 (7), pp. 3450-60. Date of Electronic Publication: 2010 Mar 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chemokine CXCL10/*immunology
Chemokine CXCL9/*immunology
Graft Rejection/*immunology
Lymphocyte Activation/*immunology
T-Lymphocytes/*immunology
Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cell Separation ; Chemokine CXCL10/metabolism ; Chemokine CXCL9/metabolism ; Flow Cytometry ; Graft Survival/immunology ; Heart Transplantation/immunology ; Interferon-gamma/biosynthesis ; Interferon-gamma/immunology ; Mice ; Mice, Transgenic ; Reverse Transcriptase Polymerase Chain Reaction ; Transplantation, Homologous
Czasopismo naukowe
Tytuł :
IFN-beta provides immuno-protection in the retina by inhibiting ICAM-1 and CXCL9 in retinal pigment epithelial cells.
Autorzy :
Hooks JJ; Immunology and Virology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA. />Nagineni CN
Hooper LC
Hayashi K
Detrick B
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2008 Mar 15; Vol. 180 (6), pp. 3789-96.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Chemokine CXCL9/*antagonists & inhibitors
Intercellular Adhesion Molecule-1/*metabolism
Interferon-beta/*physiology
Pigment Epithelium of Eye/*immunology
Cells, Cultured ; Chemokine CXCL10/biosynthesis ; Chemokine CXCL9/biosynthesis ; Gene Expression Regulation, Viral/immunology ; Humans ; Inflammation Mediators/metabolism ; Inflammation Mediators/physiology ; Intercellular Adhesion Molecule-1/biosynthesis ; Interferon-beta/biosynthesis ; Interferon-beta/metabolism ; Kinetics ; Oligonucleotide Array Sequence Analysis ; Pigment Epithelium of Eye/metabolism ; Pigment Epithelium of Eye/pathology ; Pigment Epithelium of Eye/virology ; Retinitis/immunology ; Retinitis/pathology ; Retinitis/prevention & control ; Vesicular stomatitis Indiana virus/immunology
Czasopismo naukowe
Tytuł :
CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system.
Autorzy :
Thapa M; Department of Microbiology, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA.
Welner RS
Pelayo R
Carr DJ
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2008 Jan 15; Vol. 180 (2), pp. 1098-106.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Herpesvirus 2, Human*
Central Nervous System/*immunology
Chemokine CXCL10/*metabolism
Chemokine CXCL9/*metabolism
Herpes Genitalis/*immunology
Killer Cells, Natural/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Animals ; Cell Movement ; Chemokine CXCL10/genetics ; Chemokine CXCL9/genetics ; Chemokines/metabolism ; Cytokines/metabolism ; Female ; Genetic Predisposition to Disease ; Mice ; Mice, Mutant Strains
Czasopismo naukowe
Tytuł :
Desiccating stress-induced chemokine expression in the epithelium is dependent on upregulation of NKG2D/RAE-1 and release of IFN-γ in experimental dry eye.
Autorzy :
Coursey TG; Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030.
Bohat R; Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030.
Barbosa FL; Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030.
Pflugfelder SC; Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030.
de Paiva CS; Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030 .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Nov 15; Vol. 193 (10), pp. 5264-72. Date of Electronic Publication: 2014 Oct 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*
Epithelium, Corneal/*immunology
Interferon-gamma/*immunology
Membrane Proteins/*immunology
NK Cell Lectin-Like Receptor Subfamily K/*immunology
Xerophthalmia/*immunology
Adoptive Transfer ; Animals ; Antibodies/pharmacology ; Antigens, Ly/genetics ; Antigens, Ly/immunology ; Chemokine CXCL10/genetics ; Chemokine CXCL10/immunology ; Chemokine CXCL11/genetics ; Chemokine CXCL11/immunology ; Chemokine CXCL9/genetics ; Chemokine CXCL9/immunology ; Conjunctiva/immunology ; Conjunctiva/pathology ; Desiccation ; Disease Models, Animal ; Epithelium, Corneal/pathology ; Female ; Gene Deletion ; Gene Expression Regulation ; Homeodomain Proteins/genetics ; Homeodomain Proteins/immunology ; Interferon-gamma/genetics ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NK Cell Lectin-Like Receptor Subfamily B/antagonists & inhibitors ; NK Cell Lectin-Like Receptor Subfamily B/genetics ; NK Cell Lectin-Like Receptor Subfamily B/immunology ; NK Cell Lectin-Like Receptor Subfamily K/genetics ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology ; T-Lymphocytes/transplantation ; Xerophthalmia/genetics ; Xerophthalmia/pathology
Czasopismo naukowe
Tytuł :
Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.
Autorzy :
Schwinge D; First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Carambia A; First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Quaas A; Department of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Krech T; Department of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Wegscheid C; Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; and.
Tiegs G; Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; and.
Prinz I; Institute of Immunology, Hannover Medical School, 30625 Hannover, Germany.
Lohse AW; First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Herkel J; First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;
Schramm C; First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Mar 15; Vol. 194 (6), pp. 2522-30. Date of Electronic Publication: 2015 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CXCL10/*genetics
Chemokine CXCL9/*genetics
Cholangitis/*prevention & control
Hepatitis/*prevention & control
Interleukin-17/*metabolism
Testosterone/*pharmacology
Acute Disease ; Adoptive Transfer ; Androgens/pharmacology ; Animals ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/transplantation ; Cholangitis/genetics ; Cholangitis/metabolism ; Disease Models, Animal ; Down-Regulation/drug effects ; Female ; Flow Cytometry ; Hepatitis/genetics ; Hepatitis/metabolism ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Ovalbumin/genetics ; Ovalbumin/immunology ; Peptide Fragments/genetics ; Peptide Fragments/immunology ; Reverse Transcriptase Polymerase Chain Reaction ; Sex Factors ; Testosterone/blood
Czasopismo naukowe
Tytuł :
Modulation of TNF-induced macrophage polarization by synovial fibroblasts.
Autorzy :
Donlin LT; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021; .
Jayatilleke A; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021;
Giannopoulou EG; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021; Biological Sciences Department, New York City College of Technology, City University of New York, New York, NY 11201;
Kalliolias GD; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021; Department of Medicine, Weill Cornell Medical College, New York, NY 10021; and.
Ivashkiv LB; Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY 10021; Department of Medicine, Weill Cornell Medical College, New York, NY 10021; and Weill Cornell Graduate School of Medical Sciences, New York, NY 10021.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Sep 01; Vol. 193 (5), pp. 2373-83. Date of Electronic Publication: 2014 Jul 23.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis, Rheumatoid/*immunology
Fibroblasts/*immunology
Macrophages/*immunology
Signal Transduction/*immunology
Synovial Membrane/*immunology
Tumor Necrosis Factor-alpha/*immunology
Arthritis, Rheumatoid/pathology ; Autocrine Communication/immunology ; Cells, Cultured ; Chemokine CXCL10/immunology ; Chemokine CXCL9/immunology ; Coculture Techniques ; Female ; Fibroblasts/pathology ; Genome-Wide Association Study ; Humans ; Interferon-beta/immunology ; Janus Kinases/immunology ; Macrophages/pathology ; Male ; STAT Transcription Factors/immunology ; Synovial Membrane/pathology ; Transcription, Genetic/immunology
Czasopismo naukowe
Tytuł :
NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury.
Autorzy :
Wu X; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520;
Lahiri A
Haines GK 3rd
Flavell RA
Abraham C
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Apr 01; Vol. 192 (7), pp. 3409-18. Date of Electronic Publication: 2014 Mar 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Intestines/*immunology
Nod2 Signaling Adaptor Protein/*immunology
Receptors, CXCR3/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/pharmacology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/immunology ; Bone Marrow Cells/metabolism ; CD3 Complex/immunology ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/metabolism ; Cell Movement/immunology ; Cells, Cultured ; Chemokine CXCL10/genetics ; Chemokine CXCL10/immunology ; Chemokine CXCL10/metabolism ; Chemokine CXCL9/genetics ; Chemokine CXCL9/immunology ; Chemokine CXCL9/metabolism ; Colitis/genetics ; Colitis/immunology ; Colitis/metabolism ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Flow Cytometry ; Gene Expression/drug effects ; Gene Expression/immunology ; Interferon-gamma/immunology ; Interferon-gamma/pharmacology ; Interleukin-10/genetics ; Interleukin-10/immunology ; Interleukin-10/metabolism ; Intestinal Mucosa/metabolism ; Intestines/pathology ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Immunological ; Nod2 Signaling Adaptor Protein/genetics ; Nod2 Signaling Adaptor Protein/metabolism ; Receptors, CXCR3/genetics ; Receptors, CXCR3/metabolism ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Autorzy :
Jie Z; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555;
Liang Y
Hou L
Dong C
Iwakura Y
Soong L
Cong Y
Sun J
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Apr 01; Vol. 192 (7), pp. 3289-300. Date of Electronic Publication: 2014 Mar 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-17/*immunology
Lymphocytes/*immunology
T-Lymphocytes/*immunology
Virus Diseases/*immunology
Adenoviridae/immunology ; Adenoviridae/physiology ; Animals ; Cells, Cultured ; Chemokine CXCL10/genetics ; Chemokine CXCL10/immunology ; Chemokine CXCL10/metabolism ; Chemokine CXCL9/genetics ; Chemokine CXCL9/immunology ; Chemokine CXCL9/metabolism ; Female ; Flow Cytometry ; Host-Pathogen Interactions/immunology ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interferon-gamma/metabolism ; Interleukin-17/genetics ; Interleukin-17/metabolism ; Liver/immunology ; Liver/metabolism ; Liver/virology ; Lymphocytes/classification ; Lymphocytes/metabolism ; Lymphocytic choriomeningitis virus/immunology ; Lymphocytic choriomeningitis virus/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Receptors, Interleukin-17/genetics ; Receptors, Interleukin-17/immunology ; Receptors, Interleukin-17/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; T-Lymphocytes/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; Tumor Necrosis Factor-alpha/metabolism ; Virus Diseases/virology
Czasopismo naukowe
Tytuł :
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
Autorzy :
Brenndörfer ED; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm S-141 86, Sweden.
Brass A
Karthe J
Ahlén G
Bode JG
Sällberg M
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2014 Feb 15; Vol. 192 (4), pp. 1671-80. Date of Electronic Publication: 2014 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepacivirus/*immunology
Protein Tyrosine Phosphatase, Non-Receptor Type 2/*metabolism
Ribavirin/*pharmacology
Viral Nonstructural Proteins/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Antiviral Agents/pharmacology ; Cell Differentiation/drug effects ; Chemokine CCL17/biosynthesis ; Chemokine CCL22/biosynthesis ; Chemokine CCL3/biosynthesis ; Chemokine CXCL11/biosynthesis ; Chemokine CXCL9/biosynthesis ; Hepatitis C, Chronic/immunology ; Hepatitis C, Chronic/metabolism ; Hepatitis C, Chronic/virology ; Interferon-gamma/biosynthesis ; Interleukin-10/biosynthesis ; Liver/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Mice, Transgenic ; Th1 Cells ; Th2 Cells ; Tumor Necrosis Factor-alpha/metabolism ; Viral Nonstructural Proteins/antagonists & inhibitors ; Viral Nonstructural Proteins/genetics
Czasopismo naukowe
Tytuł :
Regulation of the development of the hepatic B cell compartment during Schistosoma mansoni infection.
Autorzy :
Fairfax KC; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Everts B
Smith AM
Pearce EJ
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Oct 15; Vol. 191 (8), pp. 4202-10. Date of Electronic Publication: 2013 Sep 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*immunology
Immunoglobulin G/*immunology
Liver/*immunology
Schistosoma mansoni/*immunology
Schistosomiasis mansoni/*immunology
Adoptive Transfer ; Animals ; Bone Marrow/immunology ; Cell Movement/immunology ; Chemokine CXCL16 ; Chemokine CXCL6/biosynthesis ; Chemokine CXCL9/biosynthesis ; Inflammation/immunology ; Liver/cytology ; Lymph Nodes/cytology ; Lymph Nodes/immunology ; Lymphocyte Activation/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Transgenic ; Pertussis Toxin ; Receptors, CXCR/biosynthesis ; Receptors, CXCR3/biosynthesis ; Receptors, CXCR6 ; Receptors, Interleukin-10/biosynthesis ; Schistosomiasis mansoni/parasitology ; Spleen/cytology ; Spleen/immunology
Czasopismo naukowe
Tytuł :
Comment on "CXCL9 Causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation".
Autorzy :
O'Boyle G
Ali S
Kirby JA
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Jul 15; Vol. 191 (2), pp. 525.
Typ publikacji :
Letter; Comment
MeSH Terms :
Immunologic Memory*
Chemokine CXCL12/*metabolism
Chemokine CXCL9/*metabolism
Lymphocyte Activation/*immunology
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Animals ; Humans
Opinia redakcyjna
Tytuł :
Response to comment on "CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation".
Autorzy :
Giegold O
Ogrissek N
Radeke HH
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Jul 15; Vol. 191 (2), pp. 525-6.
Typ publikacji :
Letter; Comment
MeSH Terms :
Immunologic Memory*
Chemokine CXCL12/*metabolism
Chemokine CXCL9/*metabolism
Lymphocyte Activation/*immunology
T-Lymphocytes/*immunology
T-Lymphocytes/*metabolism
Animals ; Humans
Opinia redakcyjna
Tytuł :
T cells home to the thymus and control infection.
Autorzy :
Nobrega C; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, 4710-057 Braga, Portugal.
Nunes-Alves C
Cerqueira-Rodrigues B
Roque S
Barreira-Silva P
Behar SM
Correia-Neves M
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2013 Feb 15; Vol. 190 (4), pp. 1646-58. Date of Electronic Publication: 2013 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement/*immunology
T-Lymphocyte Subsets/*immunology
T-Lymphocyte Subsets/*microbiology
Thymus Gland/*immunology
Thymus Gland/*microbiology
Animals ; Chemokine CXCL10/biosynthesis ; Chemokine CXCL9/biosynthesis ; Immunity, Innate ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Mycobacterium avium/immunology ; Mycobacterium tuberculosis/immunology ; Receptors, CXCR3/biosynthesis ; T-Lymphocyte Subsets/pathology ; Thymus Gland/pathology ; Tuberculosis/immunology ; Tuberculosis/prevention & control
Czasopismo naukowe

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