Autor: "Chen, CS" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Therapeutic Opportunities of Targeting Histone Deacetylase Isoforms to Eradicate Cancer Stem Cells.
Autorzy:: Lin PC; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan. .
Hsieh HY; School of Pharmacy, College of Medicine, National Taiwan University, Taipei 10050, Taiwan. .
Chu PC; Department of Cosmeceutics and Graduate Institute of Cosmeceutics, China Medical University, Taichung 40402, Taiwan. .; Drug Development Center, China Medical University, Taichung 40402, Taiwan. .
Chen CS; Drug Development Center, China Medical University, Taichung 40402, Taiwan. .; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Jul 02; Vol. 19 (7). Date of Electronic Publication: 2018 Jul 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neoplasm Proteins*/antagonists & inhibitors
Neoplasm Proteins*/metabolism
Neoplasms*/drug therapy
Neoplasms*/enzymology
Histone Deacetylase Inhibitors/*therapeutic use
Histone Deacetylases/*metabolism
Neoplastic Stem Cells/*enzymology
Animals ; Humans

Czasopismo naukowe

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Skocz do pozycji: 2.

Tytuł:: Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis.
Autorzy:: Murahari S; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210, USA.
Jalkanen AL; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Current address: Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, 80523, USA.
Kulp SK; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
Chen CS; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
Modiano JF; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA.
London CA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210, USA.; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210, USA.
Kisseberth WC; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210, USA. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2017 Jan 21; Vol. 17 (1), pp. 67. Date of Electronic Publication: 2017 Jan 21.
Typ publikacji:: Journal Article
MeSH Terms:: Bone Neoplasms/*metabolism
Caspases/*metabolism
Histone Deacetylase Inhibitors/*pharmacology
Hydroxamic Acids/*pharmacology
Osteosarcoma/*metabolism
Phenylbutyrates/*pharmacology
Animals ; Bone Neoplasms/drug therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dogs ; Doxorubicin/pharmacology ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Osteosarcoma/drug therapy ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Vorinostat