Autor: "Chen, CS" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent.
Autorzy:: Chiu HC; The Ohio State University, Columbus, 43210, USA. />Soni S
Kulp SK
Curry H
Wang D
Gunn JS
Schlesinger LS
Chen CS; Pokaż więcej
Źródło:: Journal of biomedical science [J Biomed Sci] 2009 Dec 09; Vol. 16, pp. 110. Date of Electronic Publication: 2009 Dec 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Autophagy*
Francisella tularensis/*metabolism
Macrophages/*microbiology
Pyrazoles/*pharmacology
Sulfonamides/*pharmacology
Tularemia/*microbiology
Anti-Infective Agents/chemistry ; Bacterial Vaccines/immunology ; Cell Line ; Chloroquine/pharmacology ; Enzyme Inhibitors/pharmacology ; Humans ; Lysosomes/metabolism ; Microscopy, Fluorescence/methods ; Time Factors

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Skocz do pozycji: 2.

Tytuł:: PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound.
Autorzy:: Cen L; Center for Childhood Cancer, Columbus Children's Research Institute, Department of Pediatrics, The Ohio State University, Columbus, OH 43205, USA.
Hsieh FC
Lin HJ
Chen CS
Qualman SJ
Lin J; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2007 Sep 17; Vol. 97 (6), pp. 785-91.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Oncogene Protein v-akt/*metabolism
Protein Serine-Threonine Kinases/*metabolism
Pyrazoles/*pharmacology
Rhabdomyosarcoma/*drug therapy
Rhabdomyosarcoma/*metabolism
Sulfonamides/*pharmacology
Adolescent ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Cell Line, Tumor ; Child ; Child, Preschool ; Chromones/pharmacology ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Infant ; Male ; Morpholines/pharmacology ; Oncogene Protein v-akt/drug effects ; Phosphorylation/drug effects ; Protein Serine-Threonine Kinases/drug effects ; Pyrazoles/therapeutic use ; Pyruvate Dehydrogenase Acetyl-Transferring Kinase ; Rhabdomyosarcoma/enzymology ; Rhabdomyosarcoma/pathology ; Signal Transduction/drug effects ; Sulfonamides/therapeutic use ; Time Factors ; Treatment Outcome ; Tumor Cells, Cultured

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Skocz do pozycji: 3.

Tytuł:: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Autorzy:: Pyrko P; Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, USA. />Soriano N
Kardosh A
Liu YT
Uddin J
Petasis NA
Hofman FM
Chen CS
Chen TC
Schönthal AH; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2006 May 18; Vol. 5, pp. 19. Date of Electronic Publication: 2006 May 18.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Gene Expression Regulation/*drug effects
Microtubule-Associated Proteins/*metabolism
Neoplasm Proteins/*metabolism
Pyrazoles/*pharmacology
Sulfonamides/*pharmacology
Animals ; Antineoplastic Agents/therapeutic use ; Camptothecin/analogs & derivatives ; Camptothecin/pharmacology ; Celecoxib ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Down-Regulation ; HCT116 Cells ; Humans ; Inhibitor of Apoptosis Proteins ; Irinotecan ; Male ; Mice ; Mice, Nude ; Microtubule-Associated Proteins/genetics ; Neoplasm Proteins/genetics ; Neuroblastoma/drug therapy ; Neuroblastoma/pathology ; Promoter Regions, Genetic/genetics ; Pyrazoles/therapeutic use ; Sulfonamides/therapeutic use ; Survivin ; Transcription, Genetic ; Transfection ; Xenograft Model Antitumor Assays

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