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Wyświetlanie 1-12 z 12
Tytuł :
LncRNA RP11-79H23.3 Functions as a Competing Endogenous RNA to Regulate PTEN Expression through Sponging hsa-miR-107 in the Development of Bladder Cancer.
Autorzy :
Chi H; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
Yang R; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
Zheng X; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
Zhang L; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China. .
Jiang R; Laboratory of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing 400016, China. .
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2018 Aug 26; Vol. 19 (9). Date of Electronic Publication: 2018 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
RNA Interference*
MicroRNAs/*genetics
PTEN Phosphohydrolase/*genetics
RNA, Long Noncoding/*genetics
Urinary Bladder Neoplasms/*genetics
Adult ; Aged ; Apoptosis/genetics ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Down-Regulation ; Female ; Gene Expression Profiling ; Humans ; Male ; Middle Aged ; Models, Molecular ; Neoplasm Grading ; Neoplasm Metastasis ; Neoplasm Staging ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł :
lncRNA H19 regulates epithelial-mesenchymal transition and metastasis of bladder cancer by miR-29b-3p as competing endogenous RNA.
Autorzy :
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China.
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing 400016, PR China.
Huang M; College of Clinical Medicine, Southwest Medical University, Luzhou 646000, Sichuan, PR China.
Tian Q; Department of Cell Biology and Genetics, Southwest Medical University, Luzhou 646000, Sichuan, PR China.
Jiang R; Laboratory of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing, PR China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2017 Oct; Vol. 1864 (10), pp. 1887-1899. Date of Electronic Publication: 2017 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA (Cytosine-5-)-Methyltransferases/*genetics
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
Urinary Bladder Neoplasms/*genetics
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness/genetics ; Neoplasm Metastasis ; RNA/genetics ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Circular RNA MYLK as a competing endogenous RNA promotes bladder cancer progression through modulating VEGFA/VEGFR2 signaling pathway.
Autorzy :
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing, 400016, PR China.
Huang M; College of Clinical Medicine, Southwest Medical University, Luzhou, 646000, PR China.
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, PR China.
He Y; Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing 400016, PR China.
Duan C; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, PR China.
Zhang L; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, Chongqing 400016, PR China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2017 Sep 10; Vol. 403, pp. 305-317. Date of Electronic Publication: 2017 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
RNA/*metabolism
RNA, Neoplasm/*metabolism
Urinary Bladder Neoplasms/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Vascular Endothelial Growth Factor Receptor-2/*metabolism
Animals ; Apoptosis ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Disease Progression ; Epithelial-Mesenchymal Transition ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Gene Expression Regulation, Neoplastic ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice, Inbred BALB C ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Neoplasm Grading ; Neoplasm Invasiveness ; Neovascularization, Pathologic ; Neovascularization, Physiologic ; RNA/genetics ; RNA, Circular ; RNA, Neoplasm/genetics ; Signal Transduction ; Time Factors ; Transfection ; Urinary Bladder Neoplasms/blood supply ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/pathology ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor Receptor-2/genetics ; ras Proteins/metabolism
Czasopismo naukowe
Tytuł :
Genome-Wide Screen of miRNAs and Targeting mRNAs Reveals the Negatively Regulatory Effect of miR-130b-3p on PTEN by PI3K and Integrin β1 Signaling Pathways in Bladder Carcinoma.
Autorzy :
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing 400016, China. .
Chi H; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
Huang M; College of Clinical Medicine, Southwest Medical University, Luzhou 646000, China. .
Jiang R; Laboratory of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing 400016, China. .
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2016 Dec 31; Vol. 18 (1). Date of Electronic Publication: 2016 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study/*methods
MicroRNAs/*genetics
Oligonucleotide Array Sequence Analysis/*methods
PTEN Phosphohydrolase/*genetics
Urinary Bladder Neoplasms/*genetics
Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Integrin beta1/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Autorzy :
Zhuang X; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, China.
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, China.
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing, 400016, China.
Zhang L; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, 400016, China.
Jiang R; Laboratory of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing, China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, China. .
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Źródło :
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2016 Aug 30; Vol. 35 (1), pp. 130. Date of Electronic Publication: 2016 Aug 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carrier Proteins/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Urinary Bladder Neoplasms/*metabolism
Urinary Bladder Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cytoplasm/metabolism ; Down-Regulation ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Neoplasm Metastasis ; Neoplasm Transplantation ; Protein Binding ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma.
Autorzy :
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing 400016, China.
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China.
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Źródło :
Scientific reports [Sci Rep] 2016 Aug 03; Vol. 6, pp. 30919. Date of Electronic Publication: 2016 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Cyclin-Dependent Kinase 6/*metabolism
MicroRNAs/*genetics
RNA/*genetics
Urinary Bladder Neoplasms/*genetics
Apoptosis ; Biomarkers, Tumor/genetics ; Cell Movement ; Cell Proliferation ; Cyclin-Dependent Kinase 6/genetics ; Gene Expression Profiling ; Humans ; Prognosis ; RNA, Circular ; Tumor Cells, Cultured ; Urinary Bladder Neoplasms/metabolism ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Comprehensive analysis of differentially expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in bladder carcinoma.
Autorzy :
Huang M; College of Clinical Medicine, Southwest Medical University, Luzhou 646000, China.
Zhong Z; The First Clinical College, Chongqing Medical University, Chongqing 400016, China.
Lv M; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China.
Shu J; Department of Clinical Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Tian Q; Department of Cell Biology and Genetics, Southwest Medical University, Luzhou 646000, China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China.
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Źródło :
Oncotarget [Oncotarget] 2016 Jul 26; Vol. 7 (30), pp. 47186-47200.
Typ publikacji :
Journal Article
MeSH Terms :
RNA/*biosynthesis
RNA, Long Noncoding/*biosynthesis
Urinary Bladder Neoplasms/*genetics
Cell Differentiation ; Disease Progression ; Humans ; Microarray Analysis ; RNA/genetics ; RNA, Circular ; RNA, Long Noncoding/genetics ; Urinary Bladder Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Downregulation of angiogenin inhibits the growth and induces apoptosis in human bladder cancer cells through regulating AKT/mTOR signaling pathway.
Autorzy :
Shu J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Huang M
Tian Q
Shui Q
Zhou Y
Chen J
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Źródło :
Journal of molecular histology [J Mol Histol] 2015 Apr; Vol. 46 (2), pp. 157-71. Date of Electronic Publication: 2015 Jan 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Lung Neoplasms/*enzymology
Ribonuclease, Pancreatic/*metabolism
Urinary Bladder Neoplasms/*enzymology
Animals ; Cell Line, Tumor ; Cell Proliferation ; Cell Shape ; Down-Regulation ; Humans ; Lung Neoplasms/secondary ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Transplantation ; Proto-Oncogene Proteins c-akt/metabolism ; Ribonuclease, Pancreatic/genetics ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Angiogenin interacts with ribonuclease inhibitor regulating PI3K/AKT/mTOR signaling pathway in bladder cancer cells.
Autorzy :
Peng Y; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, PR China; The First Clinical College, Chongqing Medical University, Chongqing 400016, PR China.
Li L; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, PR China; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China.
Huang M; Department of Clinical Medicine, Luzhou Medical College, Luzhou 646000, PR China.
Duan C; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, PR China; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China.
Zhang L; The First Clinical College, Chongqing Medical University, Chongqing 400016, PR China.
Chen J; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, PR China; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, PR China. Electronic address: .
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Źródło :
Cellular signalling [Cell Signal] 2014 Dec; Vol. 26 (12), pp. 2782-92. Date of Electronic Publication: 2014 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Phosphatidylinositol 3-Kinases/*metabolism
Placental Hormones/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Ribonuclease, Pancreatic/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Urinary Bladder Neoplasms/*enzymology
Animals ; Cell Line, Tumor ; Cell Proliferation ; Fluorescence Resonance Energy Transfer ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/secondary ; Mice, Inbred BALB C ; Mice, Nude ; Mutant Proteins/metabolism ; Plasmids/metabolism ; Protein Binding ; Transfection ; Up-Regulation ; Urinary Bladder Neoplasms/pathology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.
Autorzy :
Xiong D; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China.
Liou Y; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China.
Shu J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China.
Li D; Pathology Department, Chongqing Medical University, Chongqing 400016, China.
Zhang L; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China.
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Chongqing 400016, China; Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China. Electronic address: .
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Źródło :
Experimental and molecular pathology [Exp Mol Pathol] 2014 Jun; Vol. 96 (3), pp. 411-21. Date of Electronic Publication: 2014 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Down-Regulation*
Signal Transduction*
Carrier Proteins/*metabolism
Epithelial-Mesenchymal Transition/*genetics
Urinary Bladder Neoplasms/*genetics
Animals ; Cadherins/genetics ; Cadherins/metabolism ; Carrier Proteins/genetics ; Cell Adhesion ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cytoskeleton/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Transplantation ; Protein-Serine-Threonine Kinases/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Urinary Bladder Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells.
Autorzy :
Zhu J; Department of Cell Biology and Genetics, Chongqing Medical University,Chongqing 400016, China.
Pan X
Zhang Z
Gao J
Zhang L
Chen J
Pokaż więcej
Źródło :
Cellular signalling [Cell Signal] 2012 Jun; Vol. 24 (6), pp. 1323-32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial-Mesenchymal Transition*
Protein-Serine-Threonine Kinases/*genetics
Urinary Bladder Neoplasms/*enzymology
Urinary Bladder Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Down-Regulation ; Humans ; Lung Neoplasms/secondary ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Metastasis/genetics ; RNA Interference ; Urinary Bladder/enzymology ; Urinary Bladder/metabolism ; Urinary Bladder/pathology ; Urinary Bladder Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials.
Autorzy :
Chen J; Department of Cell Biology and Genetics, Chongqing Medical University, Yuzhong District, Chongqing, People's Republic of China. />Ou-Yang X
Gao J
Zhu J
He X
Rong J
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2011 Mar; Vol. 349 (1-2), pp. 83-95. Date of Electronic Publication: 2010 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carrier Proteins/*genetics
Neoplasm Invasiveness/*genetics
RNA, Small Interfering/*genetics
Urinary Bladder Neoplasms/*pathology
Animals ; Cadherins/metabolism ; Carrier Proteins/metabolism ; Cell Movement/genetics ; Cell Proliferation ; Cell Shape ; Collagenases/metabolism ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Neoplasm Metastasis ; Neoplasm Transplantation ; Neovascularization, Pathologic/genetics ; RNA Interference ; Transplantation, Heterologous ; Tumor Burden ; Urinary Bladder Neoplasms/blood supply ; Urinary Bladder Neoplasms/genetics
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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