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Wyszukujesz frazę ""Chen, Yuxin"" wg kryterium: Autor


Wyświetlanie 1-11 z 11
Tytuł:
Novel Bradykinin Receptor Inhibitors Inhibit Proliferation and Promote the Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the ERK Pathway.
Autorzy:
Wang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Zhang B; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Huang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Yao W; Jiangsu ProteLight Pharmaceutical & Biotechnology Co., Ltd., Jiangyin 214437, China.
Tao F; Jiangsu ProteLight Pharmaceutical & Biotechnology Co., Ltd., Jiangyin 214437, China.
Chen Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.; Jiangsu ProteLight Pharmaceutical & Biotechnology Co., Ltd., Jiangyin 214437, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 26; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 26.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Bradykinin Receptor Antagonists/*pharmacology
Carcinoma, Hepatocellular/*metabolism
Cell Proliferation/*drug effects
Liver Neoplasms/*metabolism
Bradykinin Receptor Antagonists/chemical synthesis ; Bradykinin Receptor Antagonists/chemistry ; Carcinoma, Hepatocellular/drug therapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Inhibitory Concentration 50 ; Liver Neoplasms/drug therapy ; MAP Kinase Signaling System/drug effects
Czasopismo naukowe
Tytuł:
Coadministration of kla peptide with HPRP-A1 to enhance anticancer activity.
Autorzy:
Hao W; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China.; School of Life Sciences, Jilin University, Changchun, China.
Hu C; Ministry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun, China.; International Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun, China.
Huang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China.; School of Life Sciences, Jilin University, Changchun, China.
Chen Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China.; School of Life Sciences, Jilin University, Changchun, China.; JiangsuProteLight Pharmaceutical & Biotechnology Co., Ltd., Jiangyin, China.
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Źródło:
PloS one [PLoS One] 2019 Nov 08; Vol. 14 (11), pp. e0223738. Date of Electronic Publication: 2019 Nov 08 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*administration & dosage
Antineoplastic Agents/*pharmacology
Intercellular Signaling Peptides and Proteins/*administration & dosage
Intercellular Signaling Peptides and Proteins/*pharmacology
Peptides/*administration & dosage
Peptides/*pharmacology
A549 Cells ; Amino Acid Sequence ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Apoptosis/drug effects ; Chemical Phenomena ; Drug Synergism ; Female ; Humans ; Intercellular Signaling Peptides and Proteins/chemistry ; Intercellular Signaling Peptides and Proteins/metabolism ; MCF-7 Cells ; Mice ; NIH 3T3 Cells ; Peptides/chemistry ; Peptides/metabolism ; Protein Transport ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Enantiomeric Effect of d-Amino Acid Substitution on the Mechanism of Action of α-Helical Membrane-Active Peptides.
Autorzy:
Sun S; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. .; School of Life Sciences, Jilin University, Changchun 130012, China. .
Zhao G; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. .; School of Life Sciences, Jilin University, Changchun 130012, China. .
Huang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. .; School of Life Sciences, Jilin University, Changchun 130012, China. .; National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun 130012, China. .
Cai M; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
Yan Q; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
Wang H; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
Chen Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. chen_yuxin@jlu.edu.cn.; School of Life Sciences, Jilin University, Changchun 130012, China. chen_yuxin@jlu.edu.cn.; National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun 130012, China. chen_yuxin@jlu.edu.cn.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 Dec 27; Vol. 19 (1). Date of Electronic Publication: 2017 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents/*chemistry
Anti-Bacterial Agents/*pharmacology
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Peptides/*chemistry
Peptides/*pharmacology
Amino Acid Sequence ; Amino Acid Substitution ; Anti-Bacterial Agents/metabolism ; Antineoplastic Agents/metabolism ; Cell Line, Tumor ; Escherichia coli/drug effects ; Escherichia coli Infections/drug therapy ; Humans ; Hydrophobic and Hydrophilic Interactions ; Microbial Sensitivity Tests ; Neoplasms/drug therapy ; Peptides/genetics ; Protein Structure, Secondary ; Stereoisomerism
Czasopismo naukowe
Tytuł:
12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT.
Autorzy:
Zhu G; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Chen Y; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Zhang X; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Wu Q; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Zhao Y; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Chen Y; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Sun F; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.
Qiao Y; School of Public Health, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
Wang J; Department of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.; Tongji University Advanced Institute of Translational Medicine, Shanghai, 200092, China.
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Źródło:
Scientific reports [Sci Rep] 2017 Mar 21; Vol. 7, pp. 44940. Date of Electronic Publication: 2017 Mar 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Intercellular Signaling Peptides and Proteins/*metabolism
Liver Neoplasms/*metabolism
Membrane Proteins/*metabolism
Nuclear Proteins/*antagonists & inhibitors
Tetradecanoylphorbol Acetate/*pharmacology
Transcription Factors/*antagonists & inhibitors
Angiomotins ; Animals ; Caspase 3/metabolism ; Caspase 7/metabolism ; Cell Cycle Proteins ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Disease Models, Animal ; Gene Expression ; Heterografts ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Liver Neoplasms/genetics ; Membrane Proteins/genetics ; Mice ; Microfilament Proteins ; Phenotype ; Protein Transport ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy.
Autorzy:
Hao X; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China; School of Life Sciences, Jilin University, Changchun, China.
Yan Q; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China; School of Life Sciences, Jilin University, Changchun, China.
Zhao J; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China; School of Life Sciences, Jilin University, Changchun, China.
Wang W; Changchun ProteLight Pharmaceutical & Biotechnology Co., Ltd., Changchun, China.
Huang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China; School of Life Sciences, Jilin University, Changchun, China; National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun, China.
Chen Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China; School of Life Sciences, Jilin University, Changchun, China; National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun, China.
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Źródło:
PloS one [PLoS One] 2015 Sep 25; Vol. 10 (9), pp. e0138911. Date of Electronic Publication: 2015 Sep 25 (Print Publication: 2015).
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacokinetics
Peptide Fragments/*chemical synthesis
Peptide Fragments/*pharmacokinetics
tat Gene Products, Human Immunodeficiency Virus/*chemistry
Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Apoptosis ; Caspases/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; HeLa Cells ; Hep G2 Cells ; Humans ; Organ Specificity ; Peptide Fragments/chemistry ; Peptide Fragments/pharmacology
Czasopismo naukowe
Tytuł:
Tryptophan as a probe to study the anticancer mechanism of action and specificity of α-helical anticancer peptides.
Autorzy:
Li G; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China.
Huang Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China.
Feng Q; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China.
Chen Y; Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. chen_yuxin@jlu.edu.cn.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2014 Aug 13; Vol. 19 (8), pp. 12224-41. Date of Electronic Publication: 2014 Aug 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*chemistry
Fluorescent Dyes/*chemistry
Peptides/*chemistry
Tryptophan/*chemistry
Amino Acid Sequence ; Antineoplastic Agents/administration & dosage ; Cell Membrane/chemistry ; Cell Membrane/ultrastructure ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lipid Bilayers/chemistry ; Protein Structure, Secondary ; Structure-Activity Relationship ; Thermodynamics
Czasopismo naukowe
Tytuł:
Immunoglobulin superfamily 6 is a molecule involved in the anti-tumor activity of macrophages in lung adenocarcinoma.
Autorzy:
Zheng, Qisi
Wang, Ting
Jiang, Gechen
Li, Miao
Zhang, Zhi
Chen, Yuxin
Tian, Xinyu
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Temat:
ANTINEOPLASTIC agents
TUMOR-infiltrating immune cells
MACROPHAGES
GENE expression
PROGNOSIS
Źródło:
BMC Cancer; 11/30/2023, Vol. 23 Issue 1, p1-13, 13p
Czasopismo naukowe
Tytuł:
Co‐administration of kla‐TAT peptide and iRGD to enhance the permeability on A549 3D multiple sphere cells and accumulation on xenograft mice.
Autorzy:
Hu, Cuihua
Chen, Xiaolong
Huang, Yibing
Chen, Yuxin
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Temat:
DRUG administration
CELL-penetrating peptides
CYCLIC peptides
ANTINEOPLASTIC agents
XENOGRAFTS
LABORATORY mice
Źródło:
Chemical Biology & Drug Design; Aug2018, Vol. 92 Issue 2, p1567-1575, 9p
Czasopismo naukowe
Tytuł:
Enantiomeric Effect of D-Amino Acid Substitution on the Mechanism of Action of α-Helical Membrane-Active Peptides.
Autorzy:
Sun, Shiyu
Zhao, Guangxu
Huang, Yibing
Cai, Mingjun
Yan, Qiuyan
Wang, Hongda
Chen, Yuxin
Pokaż więcej
Temat:
AMINO acids
PEPTIDES
ANTI-infective agents
HEMOLYSIS & hemolysins
ANTINEOPLASTIC agents
ANTIBACTERIAL agents
Źródło:
International Journal of Molecular Sciences; Jan2018, Vol. 19 Issue 1, p67, 13p, 1 Diagram, 5 Charts, 3 Graphs
Czasopismo naukowe
Tytuł:
In vitro Characterization of the Rapid Cytotoxicity of Anticancer Peptide HPRP-A2 through Membrane Destruction and Intracellular Mechanism against Gastric Cancer Cell Lines.
Autorzy:
Zhao, Jing
Hao, Xueyu
Liu, Dong
Huang, Yibing
Chen, Yuxin
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Temat:
CELL-mediated cytotoxicity
ANTINEOPLASTIC agents
PEPTIDE drugs
INTRACELLULAR membranes
STOMACH cancer
CANCER cells
CANCER prevention
Źródło:
PLoS ONE; 09/30/2015, Vol. 10 Issue 10, p1-11, 11p
Czasopismo naukowe
    Wyświetlanie 1-11 z 11

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