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    Tytuł:
    Upregulated microRNA-125b-5p in patients with asthma-COPD overlap mediates oxidative stress and late apoptosis via targeting IL6R/TRIAP1 signaling.
    Autorzy:
    Chang YP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Tsai YH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Chen YM; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Huang KT; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Lee CP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Hsu PY; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Chen HC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
    Lin MC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .
    Chen YC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .
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    Źródło:
    Respiratory research [Respir Res] 2024 Feb 01; Vol. 25 (1), pp. 64. Date of Electronic Publication: 2024 Feb 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Apoptosis*/genetics
    Asthma*/genetics
    Asthma*/complications
    MicroRNAs*/metabolism
    Pulmonary Disease, Chronic Obstructive*/metabolism
    Humans ; Allergens ; Intracellular Signaling Peptides and Proteins/metabolism ; Oxidative Stress/genetics ; Reactive Oxygen Species ; Receptors, Interleukin-6/metabolism ; RNA, Small Interfering/metabolism ; Male ; Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Investigation of MicroRNA in Mitochondrial Apoptotic Pathway in Systemic Lupus Erythematosus.
    Autorzy:
    Su YJ; Department of Rheumatology, Allergy and Immunology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Tsai NW; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Kung CT; Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Wang HC; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Lin WC; Department of Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Huang CC; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Chang YT; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Su CM; Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Chiang YF; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
    Cheng BC; Department of Nephrology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Lin YJ; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan.
    Lu CH; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan.; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan.; Department of Neurology, Xiamen Chang Gung Memorial Hospital, Xiamen, China.
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    Źródło:
    BioMed research international [Biomed Res Int] 2018 Jul 10; Vol. 2018, pp. 9026357. Date of Electronic Publication: 2018 Jul 10 (Print Publication: 2018).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Apoptosis*
    Lupus Erythematosus, Systemic/*metabolism
    MicroRNAs/*metabolism
    Adaptor Proteins, Signal Transducing ; Female ; Humans ; Male ; Middle Aged ; Mitochondria
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Glycyrrhizin affects monocyte migration and apoptosis by blocking HMGB1 signaling.
    Autorzy:
    Tan JY; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
    Zhao F; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
    Deng SX; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
    Zhu HC; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
    Gong Y; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
    Wang W; Department of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
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    Źródło:
    Molecular medicine reports [Mol Med Rep] 2018 Apr; Vol. 17 (4), pp. 5970-5975. Date of Electronic Publication: 2018 Feb 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Apoptosis/*drug effects
    Glycyrrhizic Acid/*pharmacology
    HMGB1 Protein/*metabolism
    Monocytes/*drug effects
    Monocytes/*metabolism
    Signal Transduction/*drug effects
    Cell Line ; Cell Movement/drug effects ; Chemokine CCL2/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Mitogen-Activated Protein Kinases/metabolism ; Monocytes/immunology ; NF-kappa B/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells.
    Autorzy:
    Lin YC; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan.; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90089, USA.
    Chang YT; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan.
    Campbell M; UC Davis Cancer Center, University of California, Davis, CA 95616, USA.
    Lin TP; Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan.; Department of Urology, School of Medicine, and Shu-Tien Urological Research Center, National Yang-Ming University, Taipei, Taiwan.; Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan.
    Pan CC; Department of Pathology, Taipei Veterans General Hospital, National Yang-Ming University, Taipei, Taiwan.
    Lee HC; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.
    Shih JC; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90089, USA.; USC-Taiwan Center for Translational Research, University of Southern California, Los Angeles, CA 90089, USA.; Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, 1975 Zonal Ave., Los Angeles, CA 90033, USA.
    Chang PC; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan.; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
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    Źródło:
    Scientific reports [Sci Rep] 2017 Apr 12; Vol. 7, pp. 46338. Date of Electronic Publication: 2017 Apr 12.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*/drug effects
    Autophagy*/drug effects
    Drug Resistance, Neoplasm*
    Carcinoma, Neuroendocrine/*metabolism
    Monoamine Oxidase/*metabolism
    Prostatic Neoplasms/*metabolism
    Androgen Antagonists/pharmacology ; Androgen Antagonists/therapeutic use ; Antineoplastic Agents, Hormonal/pharmacology ; Antineoplastic Agents, Hormonal/therapeutic use ; Biomarkers ; Carcinoma, Neuroendocrine/drug therapy ; Carcinoma, Neuroendocrine/genetics ; Carcinoma, Neuroendocrine/pathology ; Cell Line, Tumor ; Enzyme Activation ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Knockdown Techniques ; Humans ; Male ; Mitophagy ; Models, Biological ; Monoamine Oxidase/genetics ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/therapeutic use ; Neoplasm Grading ; Promoter Regions, Genetic ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Protein Binding ; Reactive Oxygen Species/metabolism ; Repressor Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Autorzy:
    Chen HC; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Kanai M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Inoue-Yamauchi A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Tu HC; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Huang Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Ren D; Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA.
    Kim H; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York 11794, USA.
    Takeda S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Reyna DE; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
    Chan PM; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Ganesan YT; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Liao CP; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Gavathiotis E; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
    Hsieh JJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
    Cheng EH; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, Cornell University, New York, New York 10065, USA.
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    Źródło:
    Nature cell biology [Nat Cell Biol] 2015 Oct; Vol. 17 (10), pp. 1270-81. Date of Electronic Publication: 2015 Sep 07.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Models, Biological*
    Fibroblasts/*metabolism
    Proto-Oncogene Proteins c-bcl-2/*metabolism
    Animals ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; BH3 Interacting Domain Death Agonist Protein/genetics ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Bcl-2-Like Protein 11 ; Cells, Cultured ; Cytochromes c/genetics ; Cytochromes c/metabolism ; Embryo, Mammalian/cytology ; Embryo, Mammalian/metabolism ; Fibroblasts/cytology ; Immunoblotting ; Intestine, Small/cytology ; Intestine, Small/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/genetics ; Mitochondria/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA Interference ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism ; bcl-2 Homologous Antagonist-Killer Protein/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic Lupus erythematosus.
    Autorzy:
    Su YJ; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Cheng TT; Departments of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Chen CJ; Departments of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Chang WN; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Tsai NW; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Kung CT; Departments of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Wang HC; Departments of Neurosurgery, and Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Lin WC; Departments of Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Huang CC; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Chang YT; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Su CM; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Chiang YF; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Cheng BC; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Lin YJ; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Neurosurgery, and Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .
    Lu CH; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung, Taiwan. .; Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. .; Department of Neurology, Chang Gung Memorial Hospital, 123, Ta Pei Road, Niao Sung Hsiang, Kaohsiung, Taiwan. .
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    Źródło:
    Journal of translational medicine [J Transl Med] 2014 Nov 06; Vol. 12, pp. 303. Date of Electronic Publication: 2014 Nov 06.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Caspase 10/*metabolism
    Caspase 9/*metabolism
    Leukocytes, Mononuclear/*metabolism
    Lupus Erythematosus, Systemic/*metabolism
    Lupus Erythematosus, Systemic/*pathology
    Mitochondria/*metabolism
    Adaptor Proteins, Signal Transducing/metabolism ; Adult ; Biomarkers/metabolism ; Case-Control Studies ; Demography ; Female ; Humans ; Leukocytes, Mononuclear/enzymology ; Leukocytes, Mononuclear/pathology ; Lupus Erythematosus, Systemic/enzymology ; Lymphocytes/metabolism ; Lymphocytes/pathology ; Male ; Middle Aged ; Monocytes/metabolism ; Monocytes/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion.
    Autorzy:
    Lo HC; Department of Nutritional Science, Fu Jen Catholic University, New Taipei City, Taiwan.
    Yang RB; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
    Lee CH; Division of Pediatric Surgery, Changhua Christian Hospital, Changhau, Taiwan; Graduate Institute of Medical Sciences, Chang Jung Christian University, Tainan, Taiwan.
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    Źródło:
    PloS one [PLoS One] 2014 Jul 03; Vol. 9 (7), pp. e101314. Date of Electronic Publication: 2014 Jul 03 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Inflammation/*pathology
    Ischemia/*pathology
    Jejunum/*metabolism
    Receptors, Guanylate Cyclase-Coupled/*metabolism
    Reperfusion Injury/*pathology
    Animals ; I-kappa B Proteins/antagonists & inhibitors ; I-kappa B Proteins/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Ischemia/chemically induced ; JNK Mitogen-Activated Protein Kinases/metabolism ; Jejunum/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-KappaB Inhibitor alpha ; NF-kappa B/metabolism ; Nitrates/blood ; Nitrites/blood ; Phosphorylation ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Receptors, Guanylate Cyclase-Coupled/deficiency ; Receptors, Guanylate Cyclase-Coupled/genetics ; Reperfusion Injury/chemically induced ; p38 Mitogen-Activated Protein Kinases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Serial serum leukocyte apoptosis levels as predictors of outcome in acute traumatic brain injury.
    Autorzy:
    Wang HC; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan ; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
    Yang TM; Division of Neurosurgery, Department of Surgery, Yuan's General Hospital, Kaohsiung 80249, Taiwan.
    Lin YJ; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan ; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
    Chen WF; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
    Ho JT; Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
    Lin YT; Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
    Kwan AL; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan ; Departments of Neurosurgery, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
    Lu CH; Department of Biological Science, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan ; Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
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    Źródło:
    BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 720870. Date of Electronic Publication: 2014 Apr 17.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Apoptosis*
    Brain Injuries/*blood
    Brain Injuries/*pathology
    Leukocytes/*pathology
    Acute Disease ; Adolescent ; Adult ; Aged ; Annexin A5/metabolism ; Case-Control Studies ; Dactinomycin/analogs & derivatives ; Dactinomycin/metabolism ; Demography ; Female ; Humans ; Male ; Middle Aged ; Mitochondria/metabolism ; Prognosis ; Treatment Outcome ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Effects of the combined administration of vitamins C and E on the oxidative stress status and programmed cell death pathways after experimental spinal cord injury.
    Autorzy:
    Chen HC; 1] Department of Neurosurgery, Chang Gung Memorial Hospital, Keelung, Taiwan [2] School of Medicine, Chang Gung University, Taoyuan, Taiwan.
    Hsu PW; School of Medicine, Chang Gung University, Taoyuan, Taiwan.
    Tzaan WC; Department of Neurosurgery, Chang Gung Memorial Hospital, Keelung, Taiwan.
    Lee AW; Department of Anatomy, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
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    Źródło:
    Spinal cord [Spinal Cord] 2014 Jan; Vol. 52 (1), pp. 24-8. Date of Electronic Publication: 2013 Nov 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antioxidants/*administration & dosage
    Apoptosis/*drug effects
    Ascorbic Acid/*administration & dosage
    Oxidative Stress/*drug effects
    Spinal Cord Injuries/*pathology
    Vitamin E/*administration & dosage
    Animals ; Blotting, Western ; Disease Models, Animal ; Female ; Rats ; Rats, Sprague-Dawley ; Recovery of Function/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus.
    Autorzy:
    Su YJ
    Cheng TT
    Chen CJ
    Chiu WC
    Hsu CY
    Chang WN
    Tsai NW
    Kung CT
    Wang HC
    Lin WC
    Huang CC
    Chang YT
    Su CM
    Chiang YF
    Cheng BC
    Lin YJ
    Lu CH; Department of Neurology, Chang Gung Memorial Hospital, 123, Ta Pei Road, Niao Sung Hsiang, Kaohsiung Taiwan. .
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    Źródło:
    Journal of translational medicine [J Transl Med] 2013 Oct 19; Vol. 11, pp. 261. Date of Electronic Publication: 2013 Oct 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Autoantibodies/*blood
    Leukocytes/*cytology
    Lupus Erythematosus, Systemic/*pathology
    Adult ; Case-Control Studies ; Female ; Humans ; Lupus Erythematosus, Systemic/immunology ; Male ; Middle Aged ; Severity of Illness Index ; Sjogren's Syndrome/immunology ; Sjogren's Syndrome/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Regulatory effects of resveratrol on antioxidant enzymes: a mechanism of growth inhibition and apoptosis induction in cancer cells.
    Autorzy:
    Khan MA; Department of Biochemistry, School of Biological Science and Technology, Central South University, Changsha, Hunan 410013, China.
    Chen HC
    Wan XX
    Tania M
    Xu AH
    Chen FZ
    Zhang DZ
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    Źródło:
    Molecules and cells [Mol Cells] 2013 Mar; Vol. 35 (3), pp. 219-25. Date of Electronic Publication: 2013 Feb 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anticarcinogenic Agents/*pharmacology
    Apoptosis/*drug effects
    Cell Proliferation/*drug effects
    Stilbenes/*pharmacology
    Catalase/genetics ; Catalase/metabolism ; Gene Expression/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/metabolism ; HEK293 Cells ; Hep G2 Cells ; Humans ; Hydrogen Peroxide/metabolism ; MCF-7 Cells ; Resveratrol ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Up-Regulation/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth.
    Autorzy:
    He XP; Department of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, China.
    Shao Y
    Li XL
    Xu W
    Chen GS
    Sun HH
    Xu HC
    Xu X
    Tang D
    Zheng XF
    Xue YP
    Huang GC
    Sun WH
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    Źródło:
    The FEBS journal [FEBS J] 2012 Nov; Vol. 279 (22), pp. 4201-12. Date of Electronic Publication: 2012 Oct 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Gene Expression Regulation, Neoplastic*
    Cyclooxygenase 2/*metabolism
    MicroRNAs/*metabolism
    Stomach Neoplasms/*metabolism
    Stomach Neoplasms/*pathology
    3' Untranslated Regions ; Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Adenocarcinoma/pathology ; Adenocarcinoma, Mucinous/genetics ; Adenocarcinoma, Mucinous/metabolism ; Adenocarcinoma, Mucinous/pathology ; Animals ; Base Sequence ; Blotting, Western ; Carcinoma, Papillary/genetics ; Carcinoma, Papillary/metabolism ; Carcinoma, Papillary/pathology ; Carcinoma, Signet Ring Cell/genetics ; Carcinoma, Signet Ring Cell/metabolism ; Carcinoma, Signet Ring Cell/pathology ; Cell Adhesion ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cyclooxygenase 2/genetics ; Female ; Humans ; Lymphatic Metastasis ; Male ; Mice ; Mice, Inbred BALB C ; MicroRNAs/genetics ; Middle Aged ; Molecular Sequence Data ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Homology, Nucleic Acid ; Stomach Neoplasms/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Pipoxolan inhibits proliferation of HL-60 human leukaemia cancer cells by arresting the cell cycle at the G0/G1 phase.
    Autorzy:
    Sheu MJ; School of Pharmacy, China Medical University, 91, Hsueh-Shih Rd., Taichung, 404, Taiwan, Republic of China.
    Chou PY
    Huang CS
    Tsai IC
    Chien YC
    Lin SY
    Tsai HY
    Cheng HC
    Wu CH
    Pokaż więcej
    Źródło:
    Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2010 May; Vol. 37 (5-6), pp. 605-12. Date of Electronic Publication: 2010 Jan 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents/*pharmacology
    Apoptosis/*drug effects
    Cell Proliferation/*drug effects
    Dioxolanes/*pharmacology
    G1 Phase/*drug effects
    Resting Phase, Cell Cycle/*drug effects
    Antineoplastic Agents/chemistry ; Blotting, Western ; Caspase 3/metabolism ; Cell Culture Techniques ; Cell Survival/drug effects ; DNA Fragmentation/drug effects ; Dioxolanes/chemistry ; Flow Cytometry ; HL-60 Cells ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/pathology ; Molecular Structure ; Reactive Oxygen Species/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Impaired apoptosis and immune senescence - cause or effect?
    Autorzy:
    Hsu HC; Department of Medicine, Division of Clinical Immunology and Rheumatology, the University of Alabama at Birmingham, 35294, USA.
    Scott DK
    Mountz JD
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    Źródło:
    Immunological reviews [Immunol Rev] 2005 Jun; Vol. 205, pp. 130-46.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
    MeSH Terms:
    Apoptosis*
    Aging/*immunology
    T-Lymphocytes/*cytology
    T-Lymphocytes/*immunology
    Animals ; Antigens, CD/immunology ; Antigens, CD/metabolism ; Fas Ligand Protein ; Humans ; Membrane Glycoproteins/metabolism ; Signal Transduction ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Regulation of apoptosis proteins in cancer cells by ubiquitin.
    Autorzy:
    Zhang HG; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
    Wang J
    Yang X
    Hsu HC
    Mountz JD
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    Źródło:
    Oncogene [Oncogene] 2004 Mar 15; Vol. 23 (11), pp. 2009-15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
    MeSH Terms:
    Apoptosis*
    Gene Expression Regulation*
    Neoplasms/*metabolism
    Neoplasms/*pathology
    Proteins/*metabolism
    Ubiquitin/*metabolism
    Animals ; Humans ; Models, Biological ; Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cytoprotective response of A1, a Bcl-2 homologue expressed in mature human neutrophils and promyelocytic HL-60 cells, to oxidant stress-induced cell death.
    Autorzy:
    Liu CY; Department of Thoracic Medicine II, Chang-Gung Memorial Hospital, Taipei, Taiwan. />Chuang PI
    Chou CL
    Lin SM
    Chen HC
    Chou P
    Liu YH
    Yu CT
    Wang CH
    Lin HC
    Kuo HP
    Pokaż więcej
    Źródło:
    Journal of biomedical science [J Biomed Sci] 2004 Mar-Apr; Vol. 11 (2), pp. 214-27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    Oxidative Stress*
    DNA-Binding Proteins/*physiology
    Neutrophils/*metabolism
    Cells, Cultured ; DNA-Binding Proteins/genetics ; Granulocyte Colony-Stimulating Factor/pharmacology ; HL-60 Cells ; Humans ; Hydrogen Peroxide/pharmacology ; Neutrophils/cytology ; Peroxynitrous Acid/pharmacology ; Protective Agents ; Proto-Oncogene Proteins c-bcl-2 ; Replication Protein C ; Transfection
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-20 z 20

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