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Tytuł:
Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats.
Autorzy:
Liu Y; Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430011, China.
Xu J; Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430011, China.
Zhao L; Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430011, China.
Cheng J; Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430011, China.
Chen B; Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430011, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2021 Sep 20; Vol. 2021, pp. 1125199. Date of Electronic Publication: 2021 Sep 20 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury/*immunology
Apoptosis/*immunology
Ischemic Preconditioning/*methods
Lung/*immunology
Signal Transduction/*immunology
Acute Lung Injury/chemically induced ; Acute Lung Injury/metabolism ; Animals ; Caspases/immunology ; Caspases/metabolism ; Cytokines/immunology ; Cytokines/metabolism ; Lipopolysaccharides ; Lung/metabolism ; Lung/pathology ; Malondialdehyde/immunology ; Malondialdehyde/metabolism ; Peroxidase/immunology ; Peroxidase/metabolism ; Proto-Oncogene Proteins c-bcl-2/immunology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats, Sprague-Dawley ; Superoxide Dismutase/immunology ; Superoxide Dismutase/metabolism ; bcl-2-Associated X Protein/immunology ; bcl-2-Associated X Protein/metabolism ; Rats
Czasopismo naukowe
Tytuł:
Melatonin protects mouse testes from palmitic acid-induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1-dependent manner.
Autorzy:
Xu D; College of Animal Science and Technology, Southwest University, Chongqing, China.; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Liu L; College of Animal Science and Technology, Southwest University, Chongqing, China.
Zhao Y; College of Animal Science and Technology, Southwest University, Chongqing, China.
Yang L; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Cheng J; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Hua R; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Zhang Z; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Li Q; College of Animal Science and Technology, Northwest A&F University, Yangling, China.
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Źródło:
Journal of pineal research [J Pineal Res] 2020 Nov; Vol. 69 (4), pp. e12690. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Apoptosis/*drug effects
Endoplasmic Reticulum Stress/*drug effects
Melatonin/*pharmacology
Oxidative Stress/*drug effects
Palmitic Acid/*toxicity
Sirtuin 1/*metabolism
Animals ; Male ; Mice
Czasopismo naukowe
Tytuł:
Protective effect of apple phlorizin on hydrogen peroxide-induced cell damage in HepG2 cells.
Autorzy:
Wang H; Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science &Technology, Tianjin, China.
Cheng J; Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science &Technology, Tianjin, China.
Wang H; China National Center for Food Safety Risk Assessment, Beijing, China.
Wang M; Anhui Province Engineering Laboratory of Agricultural Products Processing, Anhui Agricultural University, Hefei, China.
Zhao J; Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science &Technology, Tianjin, China.
Wu Z; College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin, China.
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Źródło:
Journal of food biochemistry [J Food Biochem] 2019 Dec; Vol. 43 (12), pp. e13052. Date of Electronic Publication: 2019 Sep 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants/*metabolism
Apoptosis/*drug effects
DNA Damage/*drug effects
Hydrogen Peroxide/*adverse effects
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Phlorhizin/*pharmacology
Hep G2 Cells ; Humans ; Malus
Czasopismo naukowe
Tytuł:
Phospholipase C inhibits apoptosis of porcine primary granulosa cells cultured in vitro.
Autorzy:
Chen H; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Yang Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Wang Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Li Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
He Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.; Hanzhong Vocational and Technical College, Hanzhong, 723000, Shaanxi, China.
Duan J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Xu D; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Pei Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Cheng J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Yang L; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.; First Affiliated Hospital of Jiamusi University, Jiamusi, 154007, Heilongjiang, China.
Hua R; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Li X; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Wang J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Jiang X; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
He H; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Wu L; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Liu D; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Li Q; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2019 Sep 25; Vol. 12 (1), pp. 90. Date of Electronic Publication: 2019 Sep 25.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Granulosa Cells/*metabolism
Type C Phospholipases/*genetics
Animals ; Apoptosis/genetics ; Calcineurin/genetics ; Calcium/metabolism ; Caspase 3/genetics ; Cell Proliferation/genetics ; Estrenes/pharmacology ; Female ; Gene Expression Regulation/drug effects ; Granulosa Cells/drug effects ; Granulosa Cells/pathology ; Phospholipase C beta/genetics ; Phosphoprotein Phosphatases/genetics ; Proto-Oncogene Proteins c-bcl-2/genetics ; Pyrrolidinones/pharmacology ; Signal Transduction/drug effects ; Sulfonamides/pharmacology ; Swine ; bcl-2 Homologous Antagonist-Killer Protein/genetics ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł:
2-Oxonanonoidal Antibiotic Actinolactomycin Inhibits Cancer Progression by Suppressing HIF-1α.
Autorzy:
Cheng J; Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei 230027, China. .
Hu L; Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei 230027, China. .
Yang Z; Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei 230027, China. .
Suo C; Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, South China University of Technology, Guangzhou 510006, China. .
Wang YJ; Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, South China University of Technology, Guangzhou 510006, China. .
Gao P; Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei 230027, China. .; Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, South China University of Technology, Guangzhou 510006, China. .
Cui C; Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, China. .
Sun L; Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, South China University of Technology, Guangzhou 510006, China. .
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Źródło:
Cells [Cells] 2019 May 10; Vol. 8 (5). Date of Electronic Publication: 2019 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibiotics, Antineoplastic/*pharmacology
Apoptosis/*drug effects
Fatty Acids/*pharmacology
Hypoxia-Inducible Factor 1, alpha Subunit/*antagonists & inhibitors
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Lactones/*pharmacology
Neoplasms/*drug therapy
Animals ; Antibiotics, Antineoplastic/therapeutic use ; Everolimus/pharmacology ; Everolimus/therapeutic use ; Fatty Acids/therapeutic use ; Humans ; Lactones/therapeutic use ; Mice, Inbred BALB C ; Mice, Nude ; Neoplastic Processes ; PC-3 Cells ; Signal Transduction/drug effects ; Streptomyces/metabolism ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Baicalein and Ly294002 induces liver cancer cells apoptosis via regulating phosphatidyl inositol 3-kinase/Akt signaling pathway.
Autorzy:
He K; Department of Hepatobiliary Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Yu X; Department of Obstetrics and Gynecology, The Affiliated TCM Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Wang X; Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Tang L; Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Cao Y; Experimental Medicine Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Xia J; Cancer Research Center of Southwest Medical University, Luzhou, Sichuan, P.R. China.
Cheng J; Department of Hepatobiliary Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P.R. China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2018 Jun; Vol. 14 (Supplement), pp. S519-S525.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Chromones/*pharmacology
Flavanones/*pharmacology
Morpholines/*pharmacology
Phosphatidylinositol 3-Kinase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Signal Transduction/*drug effects
Apoptosis/genetics ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
Potential involvement of the 18 kDa translocator protein and reactive oxygen species in apoptosis of THP-1 macrophages induced by sonodynamic therapy.
Autorzy:
Sun X; Laboratory of Photo- and Sono-theranostic Technologies, Harbin Institute of Technology, Harbin, Heilongjiang, China.; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
Guo S; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
Wang W; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
Cao Z; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.
Dan J; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
Cheng J; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.
Cao W; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.
Tian F; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
Cao W; Laboratory of Photo- and Sono-theranostic Technologies, Harbin Institute of Technology, Harbin, Heilongjiang, China.; Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Tian Y; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, Heilongjiang, China.; Department of Pathophysiology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin, Heilongjiang, China.
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Źródło:
PloS one [PLoS One] 2018 May 10; Vol. 13 (5), pp. e0196541. Date of Electronic Publication: 2018 May 10 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Receptors, GABA/*metabolism
Ultrasonic Therapy/*methods
Aminolevulinic Acid/pharmacology ; Apoptosis/drug effects ; Cell Survival/drug effects ; Cytochromes c/metabolism ; Humans ; Macrophages/metabolism ; Macrophages/physiology ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/metabolism ; Protoporphyrins ; Reactive Oxygen Species/metabolism ; Receptors, GABA/physiology ; THP-1 Cells/physiology
Czasopismo naukowe
Tytuł:
Wip1 regulates SKOV3 cell apoptosis through the p38 MAPK signaling pathway.
Autorzy:
Feng Y; Department of Reproductive Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China.
Liu F; Department of Reproductive Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China.
Du Z; Department of Reproductive Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China.
Zhao D; Department of Surgery, The Third Hospital of Tangshan, Tangshan, Hebei 063100, P.R. China.
Cheng J; Department of Obstetrics and Gynecology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R. China.
Guo W; Department of Reproductive Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Jun; Vol. 15 (6), pp. 3651-3657. Date of Electronic Publication: 2017 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Signal Transduction*
Protein Phosphatase 2C/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Cell Line, Tumor ; Gene Expression ; Gene Silencing ; Humans ; Protein Phosphatase 2C/genetics ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł:
Mesenchymal Stem Cells Ameliorated Glucolipotoxicity in HUVECs through TSG-6.
Autorzy:
An X; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Li L; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Chen Y; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .; School of Biomedical Sciences, CHIRI Biosciences, Curtin University, GPO Box U1987, Perth, WA 6845, Australia. .
Luo A; Sichuan Neo-Life Stem Cell Biotech Inc. Chengdu 610041, China. .
Ni Z; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada. .
Liu J; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Yuan Y; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Shi M; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Chen B; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Long D; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Cheng J; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
Lu Y; Key Laboratory of Transplant Engineering and Immunology, Ministry of Health; West China Hospital, Sichuan University, Chengdu 610041, China. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2016 Apr 01; Vol. 17 (4), pp. 483. Date of Electronic Publication: 2016 Apr 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Glucose/*toxicity
Mesenchymal Stem Cells/*cytology
Palmitic Acid/*toxicity
Cell Adhesion Molecules/antagonists & inhibitors ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Chemokines/genetics ; Chemokines/metabolism ; Coculture Techniques ; Cytokines/genetics ; Cytokines/metabolism ; Flow Cytometry ; Human Umbilical Vein Endothelial Cells ; Humans ; Mesenchymal Stem Cells/metabolism ; Microscopy, Fluorescence ; NF-kappa B/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Reactive Oxygen Species/metabolism ; Real-Time Polymerase Chain Reaction ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł:
5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Inhibits RIPK1/RIPK3-Dependent Necroptosis in THP-1-Derived Foam Cells.
Autorzy:
Tian F; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Yao J; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Yan M; Department of Pathophysiology and the Key Laboratory of Cardiovascular Pathophysiology, Harbin Medical University, the Key Laboratory of Cardiovascular Research (Harbin Medical University), Ministry of Education, Harbin 150081, P. R. China.
Sun X; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Wang W; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Gao W; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Tian Z; Department of Pathophysiology and the Key Laboratory of Cardiovascular Pathophysiology, Harbin Medical University, the Key Laboratory of Cardiovascular Research (Harbin Medical University), Ministry of Education, Harbin 150081, P. R. China.
Guo S; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Dong Z; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Li B; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Gao T; Department of Forensic Medicine, Harbin Medical University, Harbin 150001, P. R. China.
Shan P; Department of Vascular Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, P. R. China.
Liu B; Department of Vascular Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, P. R. China.
Wang H; Department of Vascular Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, P. R. China.
Cheng J; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Gao Q; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.
Zhang Z; Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin 150080, P. R. China.
Cao W; Laboratory of Photo- and Sono-theranostic Technologies and Condensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin 150080, P. R. China.; Materials Research Institute, The Pennsylvania State University, University Park 16802, PA, USA.
Tian Y; Department of Cardiology, the First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, 150001, P. R. China.; Department of Pathophysiology and the Key Laboratory of Cardiovascular Pathophysiology, Harbin Medical University, the Key Laboratory of Cardiovascular Research (Harbin Medical University), Ministry of Education, Harbin 150081, P. R. China.; Heilongjiang Academy of Medical Sciences, Harbin 150086, P. R. China.
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Źródło:
Scientific reports [Sci Rep] 2016 Feb 25; Vol. 6, pp. 21992. Date of Electronic Publication: 2016 Feb 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Necrosis*
Ultrasonic Waves*
Aminolevulinic Acid/*pharmacology
Foam Cells/*metabolism
Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism
Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Atherosclerosis/therapy ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Line, Tumor ; Foam Cells/pathology ; Foam Cells/ultrastructure ; Humans ; Imidazoles/metabolism ; Indoles/metabolism
Czasopismo naukowe
Tytuł:
Reduced proliferation and increased apoptosis of the SGC‑7901 gastric cancer cell line on exposure to GDC‑0449.
Autorzy:
Wu C; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Cheng J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Hu S; Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Deng R; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Muangu YW; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Shi L; Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Wu K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Zhang P; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Chang W; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Wang G; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Tao K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 Feb; Vol. 13 (2), pp. 1434-40. Date of Electronic Publication: 2015 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anilides/*pharmacology
Apoptosis/*drug effects
Pyridines/*pharmacology
Stomach Neoplasms/*pathology
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Down-Regulation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Hedgehog Proteins/metabolism ; Humans ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Signal Transduction/drug effects ; Smoothened Receptor ; Stomach Neoplasms/genetics
Czasopismo naukowe
Tytuł:
Sonic hedgehog signaling pathway supports cancer cell growth during cancer radiotherapy.
Autorzy:
Ma J; Experimental Research Center, First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Tian L
Cheng J
Chen Z
Xu B
Wang L
Li C
Huang Q
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Źródło:
PloS one [PLoS One] 2013 Jun 10; Vol. 8 (6), pp. e65032. Date of Electronic Publication: 2013 Jun 10 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*radiation effects
Cell Proliferation/*radiation effects
Cell Transformation, Neoplastic/*pathology
Colonic Neoplasms/*pathology
Hedgehog Proteins/*metabolism
Pancreatic Neoplasms/*pathology
Signal Transduction/*radiation effects
Transcription Factors/*metabolism
Blotting, Western ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/radiotherapy ; Feeder Cells/radiation effects ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Hedgehog Proteins/agonists ; Hedgehog Proteins/antagonists & inhibitors ; Humans ; Luciferases/genetics ; Luciferases/metabolism ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/radiotherapy ; RNA, Small Interfering/genetics ; Radiotherapy Dosage ; Transcription Factors/agonists ; Transcription Factors/antagonists & inhibitors ; Tumor Cells, Cultured ; X-Rays ; Zinc Finger Protein GLI1
Czasopismo naukowe
Tytuł:
Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
Autorzy:
Wang J; State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Liu L
Qiu H
Zhang X
Guo W
Chen W
Tian Y
Fu L
Shi D
Cheng J
Huang W
Deng W
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Źródło:
PloS one [PLoS One] 2013 May 30; Vol. 8 (5), pp. e63872. Date of Electronic Publication: 2013 May 30 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Colonic Neoplasms/*pathology
Signal Transduction/*drug effects
Triterpenes/*pharmacology
Acetylation/drug effects ; Caspases/metabolism ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclooxygenase 2/metabolism ; Cytochromes c/metabolism ; Dinoprostone/metabolism ; E1A-Associated p300 Protein/metabolism ; Humans ; NF-kappa B/metabolism ; Protein Transport/drug effects ; Time Factors ; Ursolic Acid
Czasopismo naukowe
Tytuł:
Association of genetic markers in the BCL-2 family of apoptosis-related genes with endometrial cancer risk in a Chinese population.
Autorzy:
Dorjgochoo T; Division of Epidemiology, Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.
Xiang YB
Long J
Shi J
Deming S
Xu WH
Cai H
Cheng J
Cai Q
Zheng W
Shu XO
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Źródło:
PloS one [PLoS One] 2013 Apr 23; Vol. 8 (4), pp. e60915. Date of Electronic Publication: 2013 Apr 23 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Polymorphism, Single Nucleotide*
Apoptosis/*genetics
Asian People/*genetics
Endometrial Neoplasms/*genetics
Genetic Markers/*genetics
Genetic Predisposition to Disease/*genetics
Proto-Oncogene Proteins c-bcl-2/*genetics
Adult ; Aged ; Case-Control Studies ; Endometrial Neoplasms/pathology ; Female ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł:
p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway.
Autorzy:
Shi Y; MOE Key Lab of Environment and Health, Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Song Y
Wang Y
Liang X
Hu Y
Guan X
Cheng J
Yang K
Pokaż więcej
Źródło:
Journal of biomedicine & biotechnology [J Biomed Biotechnol] 2009; Vol. 2009, pp. 181282. Date of Electronic Publication: 2009 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Dichlorodiphenyl Dichloroethylene/*toxicity
Fas Ligand Protein/*metabolism
Sertoli Cells/*cytology
Sertoli Cells/*drug effects
Acetylcysteine/pharmacology ; Animals ; Annexins/metabolism ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 8/genetics ; Caspase 8/metabolism ; Cell Shape/drug effects ; Cell Survival/drug effects ; Male ; Models, Biological ; NF-kappa B/metabolism ; Propidium/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Sertoli Cells/enzymology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
The potential of the tumor microenvironment to influence Apo2L/TRAIL induced apoptosis.
Autorzy:
Mace TA; Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
Yamane N
Cheng J
Hylander BL
Repasky EA
Pokaż więcej
Źródło:
Immunological investigations [Immunol Invest] 2006; Vol. 35 (3-4), pp. 279-96.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*physiology
Apoptosis Regulatory Proteins/*pharmacology
Drug Resistance, Neoplasm/*physiology
Membrane Glycoproteins/*pharmacology
Neoplasms, Experimental/*drug therapy
Tumor Necrosis Factor-alpha/*pharmacology
Animals ; Apoptosis/drug effects ; Humans ; Mice ; Mice, SCID ; Neoplasms, Experimental/blood supply ; Neoplasms, Experimental/metabolism ; Recombinant Proteins/pharmacology ; TNF-Related Apoptosis-Inducing Ligand
Czasopismo naukowe
Tytuł:
Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.
Autorzy:
Yuan ZQ; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, Tampa 33612, USA.
Sun M
Feldman RI
Wang G
Ma X
Jiang C
Coppola D
Nicosia SV
Cheng JQ
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Źródło:
Oncogene [Oncogene] 2000 May 04; Vol. 19 (19), pp. 2324-30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Tumor Suppressor Proteins*
Apoptosis/*physiology
Ovarian Neoplasms/*metabolism
Ovarian Neoplasms/*pathology
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins/*metabolism
Adenocarcinoma, Mucinous/metabolism ; Adenocarcinoma, Mucinous/pathology ; Adenocarcinoma, Papillary/metabolism ; Adenocarcinoma, Papillary/pathology ; Adenosarcoma/metabolism ; Adenosarcoma/pathology ; Amino Acid Sequence ; Blotting, Western ; Chromones/pharmacology ; Conserved Sequence ; Cystadenocarcinoma/metabolism ; Cystadenocarcinoma/pathology ; Female ; Fibroma/metabolism ; Fibroma/pathology ; Histones/metabolism ; Humans ; Molecular Sequence Data ; Morpholines/pharmacology ; Oncogene Proteins/metabolism ; PTEN Phosphohydrolase ; Phosphoinositide-3 Kinase Inhibitors ; Phosphoric Monoester Hydrolases/metabolism ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/immunology ; Proto-Oncogene Proteins c-akt ; Thecoma/metabolism ; Thecoma/pathology
Czasopismo naukowe
Tytuł:
Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule.
Autorzy:
Cheng J; University of Alabama at Birmingham.
Zhou T
Liu C
Shapiro JP
Brauer MJ
Kiefer MC
Barr PJ
Mountz JD
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1994 Mar 25; Vol. 263 (5154), pp. 1759-62.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Apoptosis*
Antigens, Surface/*physiology
Amino Acid Sequence ; Animals ; Antibodies/immunology ; Antigens, Surface/chemistry ; Antigens, Surface/genetics ; Antigens, Surface/immunology ; Arthritis, Rheumatoid/blood ; Base Sequence ; Cell Line ; Cell Membrane/chemistry ; Humans ; Lupus Erythematosus, Systemic/blood ; Mice ; Molecular Sequence Data ; RNA, Messenger/genetics ; Solubility ; T-Lymphocyte Subsets/immunology ; Transfection ; fas Receptor
Czasopismo naukowe
Tytuł:
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis
Autorzy:
Li Z
Cheng J
Liu J
Pokaż więcej
Temat:
osteoarthritis
apoptosis-inducing factor mitochondria-associated 1
baicalin
apoptosis
Therapeutics. Pharmacology
RM1-950
Źródło:
Drug Design, Development and Therapy, Vol Volume 14, Pp 2645-2655 (2020)
Opis pliku:
electronic resource
Relacje:
https://www.dovepress.com/baicalin-protects-human-oa-chondrocytes-against-il-1beta-induced-apopt-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881
Dostęp URL:
https://doaj.org/article/bbacb7922225468886d2c70e65fb4be1  Link otwiera się w nowym oknie
Czasopismo naukowe
Tytuł:
Active Monomer RTR-1 Derived from the Root of Rhodomyrtus tomentosa Induces Apoptosis in Gastric Carcinoma Cells by Inducing ER Stress and Inhibiting the STAT3 Signaling Pathway
Autorzy:
Zhang X
Cheng J
He P
Zhu J
Chen Z
Miao S
Wang G
Jiang J
Wang Y
Pokaż więcej
Temat:
rtr-1
gastric carcinoma cells
cell cycle
apoptosis
er stress
stat3
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Cancer Management and Research, Vol Volume 12, Pp 3117-3129 (2020)
Opis pliku:
electronic resource
Relacje:
https://www.dovepress.com/active-monomer-rtr-1-derived-from-the-root-of-rhodomyrtus-tomentosa-in-peer-reviewed-article-CMAR; https://doaj.org/toc/1179-1322
Dostęp URL:
https://doaj.org/article/70380f116fba428bb2d03ab574f9e32c  Link otwiera się w nowym oknie
Czasopismo naukowe

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