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    Tytuł:
    Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates.
    Autorzy:
    Isaacs A; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.
    Cheung STM; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.
    Thakur N; The Pirbright Institute, Pirbright, Woking GU24 0NF, UK.
    Jaberolansar N; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.; The Australian Institute for Biotechnology and Nanotechnology, University of Queensland, Saint Lucia 4067, Australia.
    Young A; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.; The Australian Institute for Biotechnology and Nanotechnology, University of Queensland, Saint Lucia 4067, Australia.
    Modhiran N; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.
    Bailey D; The Pirbright Institute, Pirbright, Woking GU24 0NF, UK.
    Graham SP; The Pirbright Institute, Pirbright, Woking GU24 0NF, UK.
    Young PR; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.; The Australian Institute for Biotechnology and Nanotechnology, University of Queensland, Saint Lucia 4067, Australia.; Australian Infectious Disease Research Centre, University of Queensland, Saint Lucia 4067, Australia.
    Chappell KJ; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.; The Australian Institute for Biotechnology and Nanotechnology, University of Queensland, Saint Lucia 4067, Australia.; Australian Infectious Disease Research Centre, University of Queensland, Saint Lucia 4067, Australia.
    Watterson D; School of Chemistry and Molecular Biosciences, University of Queensland, Saint Lucia 4067, Australia.; Australian Infectious Disease Research Centre, University of Queensland, Saint Lucia 4067, Australia.
    Pokaż więcej
    Źródło:
    Viruses [Viruses] 2021 Sep 28; Vol. 13 (10). Date of Electronic Publication: 2021 Sep 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Viral/*blood
    Henipavirus Infections/*prevention & control
    Nipah Virus/*immunology
    Respiratory Syncytial Virus Infections/*prevention & control
    Respiratory Syncytial Virus Vaccines/*immunology
    Respiratory Syncytial Virus, Human/*immunology
    Vaccine Development/*methods
    Viral Envelope Proteins/*immunology
    Animals ; Antibodies, Viral/immunology ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Respiratory Syncytial Virus Vaccines/administration & dosage ; Vaccines, Subunit/administration & dosage ; Vaccines, Subunit/immunology ; Viral Envelope Proteins/administration & dosage ; Viral Envelope Proteins/genetics ; Viral Fusion Proteins/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A broadly protective antibody that targets the flavivirus NS1 protein.
    Autorzy:
    Modhiran N; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Song H; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
    Liu L; Division of Laboratory Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
    Bletchly C; Microbiology, Pathology Queensland, Queensland Health, Herston, Queensland, Australia.
    Brillault L; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.; Centre for Microscopy and Microanalysis, The University of Queensland, Brisbane, Australia.
    Amarilla AA; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Xu X; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
    Qi J; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
    Chai Y; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
    Cheung STM; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Traves R; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Setoh YX; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Bibby S; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Scott CAP; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Freney ME; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Newton ND; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Khromykh AA; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Chappell KJ; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Muller DA; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Stacey KJ; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Landsberg MJ; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
    Shi Y; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. .
    Gao GF; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. .; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
    Young PR; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia. .
    Watterson D; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia. .
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2021 Jan 08; Vol. 371 (6525), pp. 190-194.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Neutralizing/*chemistry
    Antibodies, Viral/*chemistry
    Dengue Virus/*immunology
    Viral Nonstructural Proteins/*immunology
    West Nile virus/*immunology
    Zika Virus/*immunology
    Animals ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/immunology ; Antibodies, Viral/therapeutic use ; CHO Cells ; Cell Line ; Cricetulus ; Cross Reactions ; Dengue/prevention & control ; Dengue/therapy ; Disease Models, Animal ; Humans ; Mice ; Protein Domains ; Viral Nonstructural Proteins/chemistry ; Viremia/therapy ; West Nile Fever/prevention & control ; West Nile Fever/therapy ; Zika Virus Infection/prevention & control ; Zika Virus Infection/therapy
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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