Autor: "Chevassut TJ" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Thrombotic risk in COVID-19: a case series and case-control study.
Autorzy:: Stoneham SM; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Falmer, UK .
Milne KM; Brighton and Sussex Medical School, Brighton, UK and Royal Sussex County Hospital, Brighton, UK.
Nuttall E; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
Frew GH; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
Sturrock BR; Brighton and Sussex Medical School, Brighton UK and Royal Sussex County Hospital, Brighton, UK.
Sivaloganathan H; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Falmer, UK.
Ladikou EE; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Falmer, UK.
Drage S; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
Phillips B; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Falmer, UK.
Chevassut TJ; Brighton and Sussex Medical School, Brighton UK and consultant haematologist, Royal Sussex County Hospital, Brighton, UK.
Eziefula AC; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Falmer, UK.; Pokaż więcej
Źródło:: Clinical medicine (London, England) [Clin Med (Lond)] 2020 Jul; Vol. 20 (4), pp. e76-e81. Date of Electronic Publication: 2020 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: Betacoronavirus*
Coronavirus Infections/*complications
Fibrin Fibrinogen Degradation Products/*metabolism
Pneumonia, Viral/*complications
Venous Thromboembolism/*blood
Venous Thromboembolism/*epidemiology
Aged ; Aged, 80 and over ; Anticoagulants/therapeutic use ; Biomarkers/blood ; COVID-19 ; Case-Control Studies ; Coronavirus Infections/blood ; Female ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Incidence ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/virology

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Skocz do pozycji: 2.

Tytuł:: The renin-angiotensin system - a therapeutic target in COVID-19?
Autorzy:: Sturrock BR; Brighton and Sussex Medical School, Brighton UK and Royal Sussex County Hospital, Brighton, UK.
Milne KM; Brighton and Sussex Medical School, Brighton UK and Royal Sussex County Hospital, Brighton, UK.
Chevassut TJ; Brighton and Sussex Medical School, Brighton UK and consultant haematologist, Royal Sussex County Hospital, Brighton, UK t.chevassut@bsms.ac.uk.; Pokaż więcej
Źródło:: Clinical medicine (London, England) [Clin Med (Lond)] 2020 Jul; Vol. 20 (4), pp. e72-e75. Date of Electronic Publication: 2020 May 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Renin-Angiotensin System*
Angiotensin II/*metabolism
Antihypertensive Agents/*therapeutic use
Betacoronavirus/*physiology
Coronavirus Infections/*metabolism
Peptidyl-Dipeptidase A/*metabolism
Pneumonia, Viral/*metabolism
Amides/therapeutic use ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme 2 ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Animals ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Fumarates/therapeutic use ; Humans ; Lung Injury/metabolism ; Lung Injury/virology ; Mice ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Virus Internalization

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Skocz do pozycji: 3.

Tytuł:: Chloroquine and COVID-19 - a potential game changer?
Autorzy:: Sturrock BR; Brighton and Sussex Medical School, Brighton UK and Royal Sussex County Hospital, Brighton, UK.
Chevassut TJ; Brighton and Sussex Medical School, Brighton UK and consultant haematologist, Royal Sussex County Hospital, Brighton, UK t.chevassut@bsms.ac.uk.; Pokaż więcej
Źródło:: Clinical medicine (London, England) [Clin Med (Lond)] 2020 May 15; Vol. 20 (3), pp. 278-281. Date of Electronic Publication: 2020 May 15.
Typ publikacji:: Journal Article

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Skocz do pozycji: 4.

Tytuł:: Epigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis.
Autorzy:: Chaudry SF; Brighton and Sussex Medical School, University of Sussex, Brighton, East Sussex BN1 9PS, UK.
Chevassut TJ; Brighton and Sussex Medical School, University of Sussex, Brighton, East Sussex BN1 9PS, UK.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 5473197. Date of Electronic Publication: 2017 Feb 14.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA (Cytosine-5-)-Methyltransferases*/biosynthesis
DNA (Cytosine-5-)-Methyltransferases*/genetics
Epigenesis, Genetic*
Gene Expression Regulation, Enzymologic*
Gene Expression Regulation, Leukemic*
Leukemia, Myeloid, Acute*/epidemiology
Leukemia, Myeloid, Acute*/genetics
Mutation, Missense*
Neoplasm Proteins*/biosynthesis
Neoplasm Proteins*/genetics
Amino Acid Substitution ; Animals ; DNA Methyltransferase 3A ; Hematopoiesis/genetics ; Humans

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Skocz do pozycji: 5.

Tytuł:: The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease.
Autorzy:: Robinson SR; Medical Research Building, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PS, UK. .
Oliver AW; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9RQ, UK. .
Chevassut TJ; Medical Research Building, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PS, UK. t.chevassut@bsms.ac.uk.
Newbury SF; Medical Research Building, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PS, UK. .; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2015 Jul 17; Vol. 5 (3), pp. 1515-39. Date of Electronic Publication: 2015 Jul 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Disease*/genetics
Exosome Multienzyme Ribonuclease Complex/*chemistry
Exosome Multienzyme Ribonuclease Complex/*metabolism
Animals ; Conserved Sequence ; Humans ; Protein Transport

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Skocz do pozycji: 6.

Tytuł:: Immunohistochemical prognostication in diffuse large B-cell lymphoma: a single center 6-year retrospective analysis.
Autorzy:: Robinson SD; a Brighton and Sussex Medical School, University of Sussex , Brighton , UK.
Gabriel J; a Brighton and Sussex Medical School, University of Sussex , Brighton , UK.
Webb A; b Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust , Brighton , UK.
Corbett T; b Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust , Brighton , UK.
Johnston R; b Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust , Brighton , UK.
Wright D; b Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust , Brighton , UK.
Chevassut TJ; a Brighton and Sussex Medical School, University of Sussex , Brighton , UK.; b Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust , Brighton , UK.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2015; Vol. 56 (10), pp. 2975-7. Date of Electronic Publication: 2015 Mar 06.
Typ publikacji:: Letter
MeSH Terms:: Lymphoma, Large B-Cell, Diffuse/*diagnosis
Lymphoma, Large B-Cell, Diffuse/*metabolism
Biomarkers ; Humans ; Immunohistochemistry ; Lymphoma, Large B-Cell, Diffuse/mortality ; Prognosis ; Retrospective Studies

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Skocz do pozycji: 7.

Tytuł:: Acute myeloid leukemia cells exhibit selective down-regulation of DNMT3A isoform 2.
Autorzy:: Stewart HJ; a Brighton and Sussex Medical School , Brighton , UK.
Shalit E; a Brighton and Sussex Medical School , Brighton , UK.
Halliday L; b Department of Life Sciences , University of Sussex , Brighton , UK.
Morey D; b Department of Life Sciences , University of Sussex , Brighton , UK.
Chevassut TJ; a Brighton and Sussex Medical School , Brighton , UK.; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2015; Vol. 56 (12), pp. 3445-8. Date of Electronic Publication: 2015 Jun 19.
Typ publikacji:: Letter
MeSH Terms:: Gene Expression Regulation, Leukemic*
DNA (Cytosine-5-)-Methyltransferases/*genetics
Leukemia, Myeloid, Acute/*genetics
DNA Methyltransferase 3A ; Down-Regulation ; Genotype ; Humans ; Mutation ; Protein Isoforms

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Skocz do pozycji: 8.

Tytuł:: DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia.
Autorzy:: Bisling KE; Brighton and Sussex Medical School, University of Sussex , Brighton , UK.
Brewin JN
McGovern AP
Horne GA
Rider T
Stewart HJ
Ramsahoye BH
Chevassut TJ; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2014 Mar; Vol. 55 (3), pp. 711-4. Date of Electronic Publication: 2013 Jul 25.
Typ publikacji:: Letter
MeSH Terms:: Mutation*
DNA (Cytosine-5-)-Methyltransferases/*genetics
Leukemia, Myeloid, Acute/*genetics
DNA Methyltransferase 3A ; Humans

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Skocz do pozycji: 9.

Tytuł:: The RAG Model: A New Paradigm for Genetic Risk Stratification in Multiple Myeloma.
Autorzy:: Prideaux SM; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.
Conway O'Brien E; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.
Chevassut TJ; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.; Pokaż więcej
Źródło:: Bone marrow research [Bone Marrow Res] 2014; Vol. 2014, pp. 526568. Date of Electronic Publication: 2014 Sep 11.
Typ publikacji:: Journal Article

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Skocz do pozycji: 10.

Tytuł:: The genetic architecture of multiple myeloma.
Autorzy:: Prideaux SM; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.
Conway O'Brien E; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.
Chevassut TJ; Brighton and Sussex Medical School, Sussex University, Falmer, Brighton BN1 9PS, UK.; Pokaż więcej
Źródło:: Advances in hematology [Adv Hematol] 2014; Vol. 2014, pp. 864058. Date of Electronic Publication: 2014 Apr 03.
Typ publikacji:: Journal Article; Review