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Tytuł :
Alvis: a tool for contig and read ALignment VISualisation and chimera detection.
Autorzy :
Martin S; Earlham Institute, Norwich Research Park, Norwich, UK.
Leggett RM; Earlham Institute, Norwich Research Park, Norwich, UK. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Mar 16; Vol. 22 (1), pp. 124. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Chimera*
High-Throughput Nucleotide Sequencing*
Sequence Analysis, DNA*
Data Visualization ; Genome ; Humans
Czasopismo naukowe
Tytuł :
Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution.
Autorzy :
Gokhman D; Department of Biology, Stanford University, Stanford, CA, USA. .
Agoglia RM; Department of Genetics, Stanford University, Stanford, CA, USA.
Kinnebrew M; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.
Gordon W; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
Sun D; Department of Biology, Stanford University, Stanford, CA, USA.
Bajpai VK; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
Naqvi S; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
Chen C; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Chan A; Yerkes National Primate Research Center, Atlanta, GA, USA.; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Chen C; Department of Oral and Maxillofacial Surgery and Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Petrov DA; Department of Biology, Stanford University, Stanford, CA, USA.
Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, CA, USA.
Zhang H; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Mishina Y; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Wysocka J; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA.
Rohatgi R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.
Fraser HB; Department of Biology, Stanford University, Stanford, CA, USA. .
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Źródło :
Nature genetics [Nat Genet] 2021 Apr; Vol. 53 (4), pp. 467-476. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera/*genetics
Ellis-Van Creveld Syndrome/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Neural Crest/*metabolism
Pan troglodytes/*genetics
Skull/*metabolism
Animals ; Biological Evolution ; Cell Differentiation ; Chimera/metabolism ; Ellis-Van Creveld Syndrome/metabolism ; Ellis-Van Creveld Syndrome/pathology ; Female ; Gene Expression ; Genotype ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Intercellular Signaling Peptides and Proteins/deficiency ; Male ; Mice ; Mice, Knockout ; Neural Crest/pathology ; Pan troglodytes/anatomy & histology ; Pan troglodytes/metabolism ; Phenotype ; Signal Transduction ; Skull/anatomy & histology ; Species Specificity ; Tetraploidy
Czasopismo naukowe
Tytuł :
GRF-GIF Chimeras Boost Plant Regeneration.
Autorzy :
Luo G; NovoCrops Centre, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.
Palmgren M; NovoCrops Centre, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark. Electronic address: .
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Źródło :
Trends in plant science [Trends Plant Sci] 2021 Mar; Vol. 26 (3), pp. 201-204. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera*
Gene Expression Regulation, Plant*
Plants
Czasopismo naukowe
Tytuł :
Chimeras for the twenty-first century.
Autorzy :
Morata Tarifa C; Preclinical Department, Andalusian Network for Advanced Therapies, Fundación Progreso y Salud, Sevilla, Spain.
López Navas L; Preclinical Department, Andalusian Network for Advanced Therapies, Fundación Progreso y Salud, Sevilla, Spain.
Azkona G; Barcelona Biomedical Research Parc (PRBB), Barcelona, Spain.
Sánchez Pernaute R; Preclinical Department, Andalusian Network for Advanced Therapies, Fundación Progreso y Salud, Sevilla, Spain.
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Źródło :
Critical reviews in biotechnology [Crit Rev Biotechnol] 2020 May; Vol. 40 (3), pp. 283-291. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chimera/*metabolism
Animals ; Bioethical Issues ; Chimera/classification ; Embryonic Stem Cells ; Humans ; Mice ; Models, Genetic ; Organogenesis ; Regenerative Medicine ; Transplantation Chimera
Czasopismo naukowe
Tytuł :
Diverse Routes toward Early Somites in the Mouse Embryo.
Autorzy :
Guibentif C; Department of Haematology, University of Cambridge, CB2 0AW Cambridge, UK; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, CB2 0AW Cambridge, UK; Sahlgrenska Center for Cancer Research, Department of Microbiology and Immunology, University of Gothenburg, 413 90 Gothenburg, Sweden.
Griffiths JA; Cancer Research UK Cambridge Institute, University of Cambridge, CB2 0RE Cambridge, UK.
Imaz-Rosshandler I; Department of Haematology, University of Cambridge, CB2 0AW Cambridge, UK; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, CB2 0AW Cambridge, UK.
Ghazanfar S; Cancer Research UK Cambridge Institute, University of Cambridge, CB2 0RE Cambridge, UK.
Nichols J; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, CB2 0AW Cambridge, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, CB2 3DY Cambridge, UK.
Wilson V; Centre for Regenerative Medicine, Institute for Stem Cell Research, School of the Biological Sciences, University of Edinburgh, EH16 4UU Edinburgh, UK. Electronic address: .
Göttgens B; Department of Haematology, University of Cambridge, CB2 0AW Cambridge, UK; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, CB2 0AW Cambridge, UK. Electronic address: .
Marioni JC; Cancer Research UK Cambridge Institute, University of Cambridge, CB2 0RE Cambridge, UK; Wellcome Sanger Institute, Wellcome Genome Campus, CB10 1SA Cambridge, UK; European Molecular Biology Laboratory, European Bioinformatics Institute, European Molecular Biology Laboratory, EBI), Wellcome Genome Campus, CB10 1SD Cambridge, UK. Electronic address: .
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Źródło :
Developmental cell [Dev Cell] 2021 Jan 11; Vol. 56 (1), pp. 141-153.e6. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Patterning/*genetics
Chimera/*metabolism
Fetal Proteins/*metabolism
Gene Expression Regulation, Developmental/*genetics
Mesoderm/*cytology
SOXB1 Transcription Factors/*metabolism
Somites/*cytology
T-Box Domain Proteins/*metabolism
Animals ; Cell Differentiation/genetics ; Cell Differentiation/physiology ; Cell Line ; Chimera/embryology ; Chimera/genetics ; Embryo, Mammalian ; Female ; Fetal Proteins/genetics ; Gene Expression Profiling ; Germ Cells/cytology ; Germ Cells/metabolism ; Heterozygote ; Male ; Mesoderm/metabolism ; Mice ; Mice, Inbred C57BL ; Single-Cell Analysis ; Somites/metabolism ; T-Box Domain Proteins/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Measuring In Vivo Neutrophil Trafficking Responses During Fungal Infection Using Mixed Bone Marrow Chimeras.
Autorzy :
Drummond RA; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. .; Institute of Immunology and Immunotherapy, Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK. .
Lionakis MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2260, pp. 179-196.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Bone Marrow Transplantation*
Cell Tracking*
Chemotaxis, Leukocyte*
Flow Cytometry*
Radiation Chimera*
Fungi/*pathogenicity
Mycoses/*microbiology
Neutrophils/*microbiology
Animals ; Disease Models, Animal ; Female ; Fungi/immunology ; Host-Pathogen Interactions ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mycoses/immunology ; Neutrophils/immunology ; Neutrophils/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Characterization of muscle development and gene expression in early embryos of chicken, quail, and their hybrids.
Autorzy :
Zhu M; College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, PR China.
Wang M; College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, PR China.
Shao Y; College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, PR China.
Nan Y; College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, PR China.
Blair HT; Institute Veterinary, Animal & Biomedical Sciences, Massey University, Auckland, Palmerston North, New Zealand.
Morris ST; Institute Veterinary, Animal & Biomedical Sciences, Massey University, Auckland, Palmerston North, New Zealand.
Zhao Z; College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, PR China. Electronic address: .
Zhang H; First Affiliated Hospital, School of Medical College, Shihezi University, Shihezi, Xinjiang 832008, PR China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 05; Vol. 768, pp. 145319. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Chimera/*embryology
Insulin-Like Growth Factor I/*genetics
Muscle, Skeletal/*growth & development
Nuclear Proteins/*genetics
Pyruvate Dehydrogenase Acetyl-Transferring Kinase/*genetics
Animals ; Breeding ; Chickens ; Chimera/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Male ; Microscopy, Atomic Force ; Muscle Development ; Muscle, Skeletal/metabolism ; Quail
Czasopismo naukowe
Tytuł :
Full donor chimerism after allogeneic hematopoietic stem cells transplant for myelofibrosis: The role of the conditioning regimen.
Autorzy :
Chiusolo P; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Bregante S; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Giammarco S; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Lamparelli T; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Casarino L; Istituto di Medicina Legale, Universita' di Genova, Genova, Italy.
Dominietto A; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Raiola AM; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Metafuni E; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Di Grazia C; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Gualandi F; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
Sora F; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Laurenti L; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Sica S; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Barosi G; Centro per lo Studio della Mielofibrosi, IRCCS Policlinico San Matteo, Pavia, Italy.
Guolo F; Istituto di Ematologia, Universita' di Genova, Genova, Italy.
Rossi M; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Rossi E; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Vannucchi A; CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, Universita' di Firenze, AOU Careggi, Florence, Italy.
Signori A; Sezione di Biostatistica, Dipartimento di Scienze della Salute, Universita' di Genova, Genova, Italy.
De Stefano V; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Bacigalupo A; Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.
Angelucci E; UO Ematologia e Trapianto di Midollo Osseo, IRCCS Ospedale Policlinico San Martino Genova, Genova, Italy.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Feb 01; Vol. 96 (2), pp. 234-240. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hematopoietic Stem Cell Transplantation*
Transplantation Chimera*
Transplantation Conditioning*
Primary Myelofibrosis/*mortality
Primary Myelofibrosis/*therapy
Adult ; Aged ; Allografts ; Busulfan/administration & dosage ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Male ; Melphalan/administration & dosage ; Middle Aged ; Splenectomy ; Survival Rate ; Thiotepa/administration & dosage
Czasopismo naukowe
Tytuł :
Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests.
Autorzy :
Madala BS; Genomics and Epigenetics Theme, Garvan Institute of Medical Research, Sydney, NSW, Australia.
Reis ALM; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.
Deveson IW; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.
Rawlinson W; School of Medical Sciences, Women's & Children's, and School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Mercer TR; Genomics and Epigenetics Theme, Garvan Institute of Medical Research, Sydney, NSW, Australia. .; Australian Institute of Bioengineering and Nanotechnology, University of Queensland, Brisbane, QLD, Australia. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jan 29; Vol. 11 (1), pp. 2636. Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera*
Amino Acid Sequence ; COVID-19/diagnosis ; COVID-19/virology ; Humans ; RNA, Viral/standards ; Reference Standards ; Reproducibility of Results ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
In Utero Hematopoietic Cell Transplantation Does Not Alter the Germ Line.
Autorzy :
Grant MT; Division of Pediatric Surgery, Department of Surgery, Washington University in St. Louis School of Medicine, St Louis, Missouri.
Vrecenak JD; Division of Pediatric Surgery, Department of Surgery, Washington University in St. Louis School of Medicine, St Louis, Missouri. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2021 Jan; Vol. 257, pp. 462-467. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera*
Fetal Therapies*
Germ Cells*
Hematopoietic Stem Cell Transplantation*
Animals ; Female ; Male ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
[Characterization of a pair of twins as blood group chimeras].
Autorzy :
Zhu Y; Qingdao Blood Center, Qingdao, Shandong 266071, China. .
Ma W
Wang H
Hu B
Feng Z
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Źródło :
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2020 Dec 10; Vol. 37 (12), pp. 1399-1402.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
ABO Blood-Group System*/genetics
Chimera*/genetics
Twins*/genetics
Alleles ; Genotype ; Humans
Czasopismo naukowe
Tytuł :
The vascular targeted citrus FLOWERING LOCUS T3 gene promotes non-inductive early flowering in transgenic Carrizo rootstocks and grafted juvenile scions.
Autorzy :
Soares JM; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Weber KC; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Qiu W; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.; Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Stanton D; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Mahmoud LM; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.; Pomology Department, Faculty of Agriculture, Mansoura University, Mansoura, Egypt.
Wu H; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Huyck P; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Zale J; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Al Jasim K; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.; College of Agriculture, Al-Qasim Green University, Babylon, Iraq.
Grosser JW; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA.
Dutt M; Citrus Research and Education Center, University of Florida, Lake Alfred, FL, 33850, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 08; Vol. 10 (1), pp. 21404. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
Chimera/*physiology
Gene Expression Profiling/*methods
Membrane Transport Proteins/*genetics
Plant Proteins/*genetics
Chimera/genetics ; Citrus/genetics ; Citrus/physiology ; Flowers/genetics ; Flowers/physiology ; Gene Expression Regulation, Plant ; High-Throughput Nucleotide Sequencing ; Phylogeny ; Plant Roots/genetics ; Plant Roots/physiology ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/physiology ; Poncirus/genetics ; Poncirus/physiology ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
4-1BB (CD137) in anticancer chimeras.
Autorzy :
Melero I; Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, Madrid, Spain.; Department of Immunology and Immunotherapy, Clínica Universidad de Navarra, Pamplona, Spain.
Berraondo P; Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, Madrid, Spain.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2020 Dec 07; Vol. 217 (12).
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Chimera*
Tumor Necrosis Factor Receptor Superfamily, Member 9*/genetics
Cell- and Tissue-Based Therapy ; Immunotherapy, Adoptive ; T-Lymphocytes, Cytotoxic
Czasopismo naukowe
Tytuł :
Genome-wide profiling of alternative splicing genes in hybrid poplar (P.alba×P.glandulosa cv.84K) leaves.
Autorzy :
Wang R; Beijing Advanced Innovation Center for Tree Breeding by Molecular Design, Beijing Forestry University, Beijing, China.; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
Yin P; Beijing Advanced Innovation Center for Tree Breeding by Molecular Design, Beijing Forestry University, Beijing, China.; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
Ruixia Y; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
Liu X; Beijing Advanced Innovation Center for Tree Breeding by Molecular Design, Beijing Forestry University, Beijing, China.; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
Luo L; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
Xu J; Beijing Advanced Innovation Center for Tree Breeding by Molecular Design, Beijing Forestry University, Beijing, China.; National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.
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Źródło :
PloS one [PLoS One] 2020 Nov 18; Vol. 15 (11), pp. e0241914. Date of Electronic Publication: 2020 Nov 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Chimera/*genetics
Plant Proteins/*genetics
Populus/*growth & development
Whole Genome Sequencing/*methods
Chimera/growth & development ; Chromosomes, Plant/genetics ; Exons ; Gene Expression Regulation, Plant ; High-Throughput Nucleotide Sequencing ; Introns ; Plant Leaves/genetics ; Plant Leaves/growth & development ; Populus/genetics ; RNA Splice Sites
Czasopismo naukowe
Tytuł :
Discovery of SK-575 as a Highly Potent and Efficacious Proteolysis-Targeting Chimera Degrader of PARP1 for Treating Cancers.
Autorzy :
Cao C; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Yang J; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Chen Y; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Zhou P; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Wang Y; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Du W; Hinova Pharmaceuticals Inc., 4th Floor, Building RongYao A, No. 5, Keyuan South Road, Chengdu 610041, China.
Zhao L; Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, China.
Chen Y; State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China.; Hinova Pharmaceuticals Inc., 4th Floor, Building RongYao A, No. 5, Keyuan South Road, Chengdu 610041, China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Oct 08; Vol. 63 (19), pp. 11012-11033. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera*
Drug Design*
Antineoplastic Agents/*therapeutic use
Neoplasms/*drug therapy
Phthalazines/*chemistry
Piperazines/*chemistry
Poly (ADP-Ribose) Polymerase-1/*metabolism
Animals ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Humans ; Ligands ; Mice ; Proteolysis
Czasopismo naukowe
Tytuł :
Culture density contributes to hepatic functions of fresh human hepatocytes isolated from chimeric mice with humanized livers: Novel, long-term, functional two-dimensional in vitro tool for developing new drugs.
Autorzy :
Yamasaki C; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Ishida Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Yanagi A; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Yoshizane Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Kojima Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Ogawa Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Kageyama Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Iwasaki Y; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.
Ishida S; Department of Pharmacology, National Institute of Health Sciences, Kanagawa, Japan.
Chayama K; Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima, Hiroshima, Japan.
Tateno C; PhoenixBio Co., Ltd., Higashi-Hiroshima, Hiroshima, Japan.; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
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Źródło :
PloS one [PLoS One] 2020 Sep 11; Vol. 15 (9), pp. e0237809. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transplantation Chimera*
Bile Canaliculi/*drug effects
Drug Development/*methods
Hepatocytes/*drug effects
Primary Cell Culture/*methods
Animals ; Bile Canaliculi/cytology ; Bile Canaliculi/metabolism ; Cells, Cultured ; Child ; Child, Preschool ; Cyclosporine/pharmacology ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 CYP3A/metabolism ; Female ; Glucuronosyltransferase/genetics ; Glucuronosyltransferase/metabolism ; Hepatocytes/cytology ; Hepatocytes/metabolism ; Humans ; Male ; Mice ; Mice, SCID ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Human-viral chimera: a novel protein affecting viral virulence and driving host T-cell immunity.
Autorzy :
Wang Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China. .
Zhang L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China.
Wu M; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, 610041, Chengdu, China. .; Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2020 Aug 25; Vol. 5 (1), pp. 167. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Chimera*
T-Lymphocytes*
Humans ; Recombinant Fusion Proteins ; Virulence
Czasopismo naukowe
Tytuł :
Chimerism in the Realm of Hematopoietic Stem Cell Transplantation for Non-malignant Disorders-A Perspective.
Autorzy :
Zimmerman C; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Shenoy S; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Aug 11; Vol. 11, pp. 1791. Date of Electronic Publication: 2020 Aug 11 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Chimerism*
Transplantation Chimera*
Hematopoietic Stem Cell Transplantation/*methods
Humans
Czasopismo naukowe
Tytuł :
A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.
Autorzy :
Vitrac A; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Pons S; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Balkota M; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Lemière N; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Raïs C; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.; Collège Doctoral, Sorbonne Université, Paris, France.
Bourgeois JP; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Maskos U; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.
Bourgeron T; Human Genetics and Cognitive Functions, CNRS UMR 3571 « Genes, Synapses and Cognition », Université de Paris, Institut Pasteur, Paris, France.
Cloëz-Tayarani I; Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 07; Vol. 10 (1), pp. 13315. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Neural Stem Cells*/metabolism
Neural Stem Cells*/pathology
Neural Stem Cells*/transplantation
Stem Cell Transplantation*
Autism Spectrum Disorder/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Nerve Tissue Proteins/*metabolism
Pyramidal Cells/*metabolism
Transplantation Chimera/*metabolism
Animals ; Autism Spectrum Disorder/genetics ; Autism Spectrum Disorder/pathology ; Cell Line ; Disease Models, Animal ; Heterografts ; Humans ; Induced Pluripotent Stem Cells/pathology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Nerve Tissue Proteins/genetics ; Pyramidal Cells/pathology ; Transplantation Chimera/genetics
Czasopismo naukowe

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