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Tytuł :
Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice.
Autorzy :
Sheng Y; Department of Medicine and.; Department of Biochemistry and Molecular Biology, UF Health Cancer Center, University of Florida, Gainesville, FL.; Department of Medicine and.
Ma R; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, IL.
Yu C; Department of Medicine and.; Department of Biochemistry and Molecular Biology, UF Health Cancer Center, University of Florida, Gainesville, FL.; Department of Medicine and.; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, IL.
Wu Q; Department of Medicine and.; Department of Biochemistry and Molecular Biology, UF Health Cancer Center, University of Florida, Gainesville, FL.; Department of Medicine and.; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, IL.
Zhang S; Department of Radiation Oncology, UF Health Cancer Center, University of Florida, Gainesville, FL.
Paulsen K; Department of Medicine and.; Department of Biochemistry and Molecular Biology, UF Health Cancer Center, University of Florida, Gainesville, FL.
Zhang J; Oncology Institute, Cardinal Bernardin Cancer Center, Department of Cancer Biology, Loyola University Medical Center, Maywood, IL.
Ni H; Department of Pathology, University of Illinois at Chicago, Chicago, IL.
Huang Y; Department of Medicine, University of Virginia, Charlottesville, VA; and.
Zheng Y; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH.
Qian Z; Department of Medicine and.; Department of Biochemistry and Molecular Biology, UF Health Cancer Center, University of Florida, Gainesville, FL.; Department of Medicine and.
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Źródło :
Blood [Blood] 2021 Feb 04; Vol. 137 (5), pp. 610-623.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, myc*
Hematopoiesis/*physiology
Proto-Oncogene Proteins c-myb/*physiology
Adenomatous Polyposis Coli Protein/physiology ; Anemia/genetics ; Anemia/prevention & control ; Animals ; Apoptosis/physiology ; Bone Marrow Transplantation ; Cell Self Renewal/physiology ; Colony-Forming Units Assay ; Endothelial Cells/pathology ; Erythroid Cells/pathology ; Gene Deletion ; Genes, APC ; Haploinsufficiency ; Hematopoiesis/genetics ; Hematopoietic Stem Cells ; Interleukin-6/physiology ; Jumonji Domain-Containing Histone Demethylases/physiology ; Mice, Mutant Strains ; Nuclear Receptor Subfamily 4, Group A, Member 1/physiology ; Nuclear Receptor Subfamily 4, Group A, Member 2/physiology ; Poly I-C/pharmacology ; Radiation Chimera ; Wnt Signaling Pathway/physiology
Czasopismo naukowe
Tytuł :
Cutaneous leukocyte lineages in tolerant large animal and immunosuppressed clinical vascularized composite allograft recipients.
Autorzy :
Leonard DA; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.; Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, Glasgow, Scotland.
Powell HR; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
Defazio MW; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
Shanmugarajah K; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Mastroianni M; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Rosales IA; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Farkash EA; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Colvin RB; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Randolph MA; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sachs DH; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Columbia Center for Translational Immunology, Columbia University Medical Center, New York, New York, USA.
Kurtz JM; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Biology, Emmanuel College, Boston, Massachusetts, USA.
Cetrulo CL Jr; Center for Transplantation Sciences, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.; Shriners Hospital for Children, Boston, Massachusetts, USA.
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Źródło :
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2021 Feb; Vol. 21 (2), pp. 582-592. Date of Electronic Publication: 2020 Aug 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Composite Tissue Allografts*
Animals ; Graft Rejection/etiology ; Graft Survival ; Humans ; Leukocytes ; Swine ; Transplantation Chimera
Czasopismo naukowe
Tytuł :
Tandem reassembly of split luciferase-DNA chimeras for bioluminescent detection of attomolar circulating microRNAs using a smartphone.
Autorzy :
Zhou L; College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, PR China.
Zhang L; College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, PR China.
Yang L; Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430061, PR China.
Ni W; Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430061, PR China. Electronic address: .
Li Y; College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, PR China. Electronic address: .
Wu Y; College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, PR China. Electronic address: .
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2021 Feb 01; Vol. 173, pp. 112824. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Biosensing Techniques*
Circulating MicroRNA*
MicroRNAs*/genetics
Chimera ; DNA ; Humans ; Luciferases ; Reproducibility of Results ; Smartphone
Czasopismo naukowe
Tytuł :
H 2 O 2 -induced cataract as a model of age-related cataract: Lessons learned from overexpressing the proteasome activator PA28αβ in mouse eye lens.
Autorzy :
Hernebring M; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Medicinaregatan 9A, PO Box 440, SE 405 30, Gothenburg, Sweden. Electronic address: .
Adelöf J; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Medicinaregatan 9A, PO Box 440, SE 405 30, Gothenburg, Sweden; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Pepparedsleden 1, SE 431 53, Mölndal, Sweden.
Wiseman J; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Pepparedsleden 1, SE 431 53, Mölndal, Sweden.
Petersen A; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Medicinaregatan 9A, PO Box 440, SE 405 30, Gothenburg, Sweden.
Zetterberg M; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Medicinaregatan 9A, PO Box 440, SE 405 30, Gothenburg, Sweden; Department of Ophthalmology, Sahlgrenska University Hospital, Area 3, Göteborgsvägen 31, SE 431 80, Mölndal, Sweden.
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Źródło :
Experimental eye research [Exp Eye Res] 2021 Feb; Vol. 203, pp. 108395. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging*
Cataract/*chemically induced
Hydrogen Peroxide/*toxicity
Lens, Crystalline/*drug effects
Oxidants/*toxicity
Proteasome Endopeptidase Complex/*metabolism
Animals ; Blotting, Western ; Cataract/metabolism ; Cataract/pathology ; Chimera ; Disease Models, Animal ; Female ; Gene Expression Regulation/physiology ; Lens, Crystalline/metabolism ; Lens, Crystalline/pathology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Organ Culture Techniques ; Proteasome Endopeptidase Complex/genetics ; Protein Carbonylation
Czasopismo naukowe
Tytuł :
Functional chimeric genes in ciliates: An instructive case from Euplotes raikovi.
Autorzy :
Ricci F; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino 62032, Italy.
Luporini P; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino 62032, Italy.
Alimenti C; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino 62032, Italy.
Vallesi A; Laboratory of Eukaryotic Microbiology and Animal Biology, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino 62032, Italy. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jan 30; Vol. 767, pp. 145186. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Chimera/*genetics
Euplotes/*genetics
Pheromones/*genetics
Amino Acid Sequence/genetics ; Base Sequence/genetics ; Ciliophora/genetics ; DNA/genetics ; Gene Rearrangement/genetics ; Introns/genetics ; RNA/genetics ; RNA Splicing/genetics
Czasopismo naukowe
Tytuł :
A Rat Model of EcoHIV Brain Infection.
Autorzy :
Li H; Program in Behavioral Neuroscience, Department of Psychology, University of South Carolina.
McLaurin KA; Program in Behavioral Neuroscience, Department of Psychology, University of South Carolina.
Mactutus CF; Program in Behavioral Neuroscience, Department of Psychology, University of South Carolina.
Booze RM; Program in Behavioral Neuroscience, Department of Psychology, University of South Carolina; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2021 Jan 21 (167). Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms :
Brain/*pathology
Brain/*virology
HIV Infections/*pathology
HIV-1/*physiology
Animals ; Chimera ; Dendritic Spines/pathology ; Disease Models, Animal ; Green Fluorescent Proteins/metabolism ; HIV Infections/complications ; Humans ; Male ; Mice ; Rats, Inbred F344 ; Stereotaxic Techniques ; Synapses/pathology ; Time Factors ; Virus Replication
Czasopismo naukowe
Tytuł :
Molecular evidence of the hybrid origin of Cryptocoryne ×purpurea Ridl. nothovar. purpurea (Araceae).
Autorzy :
Rosazlina R; School of Biological Sciences, University Sains Malaysia, Minden, Penang, Malaysia.
Jacobsen N; Department of Plant and Environmental Sciences, Section of Organismal Biology, Faculty of Science, University of Copenhagen, Frederiksberg C, Copenhagen, Denmark.
Ørgaard M; Department of Plant and Environmental Sciences, Section of Organismal Biology, Faculty of Science, University of Copenhagen, Frederiksberg C, Copenhagen, Denmark.
Othman AS; School of Biological Sciences, University Sains Malaysia, Minden, Penang, Malaysia.
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Źródło :
PloS one [PLoS One] 2021 Jan 21; Vol. 16 (1), pp. e0239499. Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Araceae/*genetics
DNA, Chloroplast/*genetics
Chimera/genetics ; DNA, Ribosomal/genetics ; DNA, Ribosomal Spacer/genetics ; Hybridization, Genetic/genetics ; Malaysia ; Phylogeny ; Sequence Analysis, DNA/methods
Czasopismo naukowe
Tytuł :
HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis.
Autorzy :
Senda N; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan.
Yanai H; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Hibino S; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Li L; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Mizushima Y; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.
Miyagaki T; Department of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan.
Saeki M; Laboratory of Molecular Biology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Kishi Y; Laboratory of Molecular Biology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Hangai S; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Nishio J; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan.; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Sugaya M; Department of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan.
Taniguchi T; Department of Molecular Immunology, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo 153-8505, Japan; .; Department of Inflammology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-ku, Tokyo 153-0041, Japan.
Sato S; Department of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin Assembly and Disassembly*
Dermatitis, Allergic Contact/*metabolism
HMGB1 Protein/*metabolism
Histones/*metabolism
Interleukins/*metabolism
Keratinocytes/*metabolism
Animals ; Dermatitis, Allergic Contact/genetics ; Dermatitis, Allergic Contact/prevention & control ; Dinitrofluorobenzene/toxicity ; Disease Models, Animal ; Ear/pathology ; Gene Deletion ; Gene Expression Regulation/genetics ; HMGB1 Protein/deficiency ; HMGB1 Protein/genetics ; Inflammation/genetics ; Inflammation/metabolism ; Interleukin-4/pharmacology ; Interleukins/genetics ; Mice ; Mice, Knockout ; Promoter Regions, Genetic ; Skin/immunology ; Skin/metabolism ; Skin/pathology ; Transplantation Chimera
Czasopismo naukowe
Tytuł :
Does early chimerism testing predict outcomes after allogeneic hematopoietic stem cell transplantation?
Autorzy :
Mountjoy L; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Palmer J; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Kunze KL; Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Phoenix, AZ, USA.
Khera N; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Sproat LZ; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Leis JF; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Noel P; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Slack JL; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
Jain T; Department of Medicine, Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2021 Jan; Vol. 62 (1), pp. 252-254. Date of Electronic Publication: 2020 Oct 04.
Typ publikacji :
Letter
MeSH Terms :
Chimerism*
Hematopoietic Stem Cell Transplantation*/adverse effects
Transplantation Chimera ; Transplantation Conditioning ; Transplantation, Homologous
Opinia redakcyjna
Tytuł :
Molecular Dynamics Simulations of Channelrhodopsin Chimera, C1C2.
Autorzy :
VanGordon MR; Department of Chemistry, University of New Orleans, New Orleans, LA, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2191, pp. 3-15.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Dynamics Simulation*
Channelrhodopsins/*chemistry
Molecular Biology/*methods
Sodium/*chemistry
Channelrhodopsins/genetics ; Chimera/genetics ; Ions/chemistry ; Lipid Bilayers/chemistry ; Solvents/chemistry ; Water/chemistry
Czasopismo naukowe
Tytuł :
Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse.
Autorzy :
Miyamoto M; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Kosugi Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Iwasaki S; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Chisaki I; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Nakagawa S; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Amano N; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
Hirabayashi H; Drug Metabolism and Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited, Fujisawa city, Japan.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jan; Vol. 51 (1), pp. 51-60. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Pharmaceutical Preparations/*metabolism
Animals ; Chimera ; Disease Models, Animal ; Hepatocytes/metabolism ; Humans ; Liver/metabolism ; Mice ; Mice, SCID ; Protein Binding/physiology
Czasopismo naukowe
Tytuł :
First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo.
Autorzy :
Wei M; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Zhao R; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Cao Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Wei Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Li M; Cangzhou Institutes for Food and Drug Control, Cangzhou, 061000, PR China.
Dong Z; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Liu Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Ruan H; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Li Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Cao S; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Tang Z; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Zhou Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Song W; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Wang Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China.
Wang J; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, PR China. Electronic address: .
Yang G; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China. Electronic address: .
Yang C; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, PR China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Jan 01; Vol. 209, pp. 112903. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Aminopyridines/*chemical synthesis
Antineoplastic Agents/*chemistry
Chimera/*metabolism
Cyclin-Dependent Kinases/*metabolism
Prodrugs/*chemical synthesis
Proteolysis/*drug effects
Purines/*chemical synthesis
Administration, Oral ; Aminopyridines/pharmacokinetics ; Animals ; Antineoplastic Agents/pharmacokinetics ; Apoptosis/drug effects ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Mice, Inbred C57BL ; Neoplasms, Experimental ; Prodrugs/pharmacokinetics ; Purines/pharmacokinetics ; Structure-Activity Relationship ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Computing Potential of the Mean Force Profiles for Ion Permeation Through Channelrhodopsin Chimera, C1C2.
Autorzy :
Priest C; Sandia National Laboratories, Albuquerque, NM, USA.
VanGordon MR; Department of Chemistry, University of New Orleans, New Orleans, LA, USA.
Rempe C; Sandia National Laboratories, Albuquerque, NM, USA.
Chaudhari MI; Sandia National Laboratories, Albuquerque, NM, USA.
Stevens MJ; Sandia National Laboratories, Albuquerque, NM, USA.
Rick S; Department of Chemistry, University of New Orleans, New Orleans, LA, USA.
Rempe SB; Sandia National Laboratories, Albuquerque, NM, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2191, pp. 17-28.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Molecular Dynamics Simulation*
Channelrhodopsins/*chemistry
Chimera/*genetics
Molecular Biology/*methods
Ions/chemistry ; Mechanical Phenomena ; Sodium/chemistry ; Thermodynamics ; Water/chemistry
Czasopismo naukowe
Tytuł :
Patterns of Late Relapse after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with T-Cell Prolymphocytic Leukemia.
Autorzy :
Shumilov E; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany.
Hasenkamp J; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany.
Szuszies CJ; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany.
Koch R; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany, .
Wulf GG; Department of Hematology and Medical Oncology, University Medicine Göttingen (UMG), Göttingen, Germany.
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Źródło :
Acta haematologica [Acta Haematol] 2021; Vol. 144 (1), pp. 105-110. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hematopoietic Stem Cell Transplantation*/adverse effects
Hematopoietic Stem Cell Transplantation*/methods
Leukemia, Prolymphocytic, T-Cell/*diagnosis
Leukemia, Prolymphocytic, T-Cell/*therapy
Combined Modality Therapy ; Female ; Graft vs Host Disease/diagnosis ; Graft vs Host Disease/etiology ; Humans ; Immunophenotyping ; Leukemia, Prolymphocytic, T-Cell/mortality ; Male ; Prognosis ; Recurrence ; Transplantation Chimera ; Transplantation Conditioning ; Transplantation, Homologous ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Mycobacterium chimaera infection after cardiac surgery: Catastrophic effects of delayed diagnosis.
Autorzy :
Vendramin I; Cardiothoracic Department, University Hospital of Udine, Udine, Italy.
Peghin M; Division of Infectious Diseases, University Hospital of Udine, Udine, Italy.
Tascini C; Division of Infectious Diseases, University Hospital of Udine, Udine, Italy.
Bortolotti U; Cardiothoracic Department, University Hospital of Udine, Udine, Italy.
Livi U; Cardiothoracic Department, University Hospital of Udine, Udine, Italy.; Department of Medical Area (DAME), University of Udine, Udine, Italy.
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Źródło :
Journal of cardiac surgery [J Card Surg] 2021 Jan; Vol. 36 (1), pp. 408. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Letter
MeSH Terms :
Cardiac Surgical Procedures*/adverse effects
Mycobacterium*
Mycobacterium Infections*/diagnosis
Mycobacterium Infections*/etiology
Mycobacterium Infections, Nontuberculous*/diagnosis
Chimera ; Delayed Diagnosis ; Humans
SCR Organism :
Mycobacterium chimaera
Opinia redakcyjna
Tytuł :
Experimental Competitive Bone Marrow Transplant Assays.
Autorzy :
Hétu-Arbour R; Institut National de la Recherche Scientifique, Laval, QC, Canada.
Bouali S; Institut National de la Recherche Scientifique, Laval, QC, Canada.
Heinonen KM; Institut National de la Recherche Scientifique, Laval, QC, Canada. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2185, pp. 195-214.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Marrow Transplantation*
Flow Cytometry*
Transplantation Conditioning*
Whole-Body Irradiation*
Transplantation Chimera/*blood
Animals ; Mice
Czasopismo naukowe
Tytuł :
Integration of metabolome and transcriptome reveals flavonoid accumulation in the intergeneric hybrid between Brassica rapa and Raphanus sativus.
Autorzy :
Zhang L; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Ma C; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Life Sciences, Northwest A&F University, Yangling, China.
Chao H; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Long Y; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Wu J; National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China.
Li Z; National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China.
Ge X; National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China.
Xia H; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yin Y; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Batley J; School of Plant Biology, The University of Western Australia, Crawley, Australia.
Li M; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China. .
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Źródło :
Scientific reports [Sci Rep] 2019 Dec 04; Vol. 9 (1), pp. 18368. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera/*genetics
Flavonoids/*genetics
Metabolome/*genetics
Transcriptome/*genetics
Brassica rapa/genetics ; Brassica rapa/metabolism ; Chimera/metabolism ; Chromosomes, Plant/genetics ; Flavonoids/metabolism ; Hybridization, Genetic ; Meiosis/genetics ; Phenotype ; Raphanus/genetics ; Raphanus/metabolism
Czasopismo naukowe
Tytuł :
Quantitative polymerase chain reaction technology in chimerism monitoring after hematopoietic stem cell transplantation: One center experience.
Autorzy :
Stingl Jankovic K; Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
Maskalan M; Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
Burek Kamenaric M; Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
Zunec R; Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
Durakovic N; Department of Hematology, University Hospital Centre Zagreb, Zagreb, Croatia.
Serventi-Seiwerth R; Department of Hematology, University Hospital Centre Zagreb, Zagreb, Croatia.
Vrhovac R; Department of Hematology, University Hospital Centre Zagreb, Zagreb, Croatia.
Grubic Z; Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
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Źródło :
HLA [HLA] 2019 Dec; Vol. 94 Suppl 2, pp. 16-20.
Typ publikacji :
Journal Article
MeSH Terms :
Chimerism*
Hematopoietic Stem Cell Transplantation*/adverse effects
Monitoring, Physiologic/*methods
Real-Time Polymerase Chain Reaction/*methods
Transplantation Chimera/*genetics
Family ; Genetic Markers ; Genotyping Techniques/methods ; Humans ; Retrospective Studies ; Transplantation Chimera/blood ; Transplantation Immunology/genetics ; Unrelated Donors
Czasopismo naukowe
Tytuł :
Limited gene exchange between two sister species of leaf beetles within a hybrid zone in the Alps.
Autorzy :
Kastally C; Evolutionary Biology and Ecology, Université Libre de Bruxelles, Brussels, Belgium.
Trasoletti M; Evolutionary Biology and Ecology, Université Libre de Bruxelles, Brussels, Belgium.
Mardulyn P; Evolutionary Biology and Ecology, Université Libre de Bruxelles, Brussels, Belgium.
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Źródło :
Journal of evolutionary biology [J Evol Biol] 2019 Dec; Vol. 32 (12), pp. 1406-1417. Date of Electronic Publication: 2019 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chimera*
Genetics, Population*
Coleoptera/*genetics
Animals ; Europe ; Gene Flow ; Genetic Variation ; Genome, Mitochondrial ; Hybridization, Genetic ; Phylogeography ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
No barrier breakdown between human and cattle schistosome species in the Senegal River Basin in the face of hybridisation.
Autorzy :
Boon NAM; Laboratory of Biodiversity and Evolutionary Genomics, Department of Biology, KU Leuven, Ch. Deberiotstraat 32, B-3000 Leuven, Belgium; Unit of Medical Helminthology, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.
Mbow M; University Cheikh Anta Diop, Department of Immunology, Dakar, Senegal.
Paredis L; Laboratory of Biodiversity and Evolutionary Genomics, Department of Biology, KU Leuven, Ch. Deberiotstraat 32, B-3000 Leuven, Belgium.
Moris P; Adrem Data Lab, Department of Mathematics and Computer Science, University of Antwerp, B-2020 Antwerp, Belgium.
Sy I; UFR Pharmacy, University of Caen Basse-Normandie, Caen, France.
Maes T; Laboratory of Biodiversity and Evolutionary Genomics, Department of Biology, KU Leuven, Ch. Deberiotstraat 32, B-3000 Leuven, Belgium; Department of Biology, Royal Museum for Central Africa, Leuvensesteenweg 13, B-3080 Tervuren, Belgium.
Webster BL; Parasites and Vectors Division, The Natural History Museum, Cromwell Road, London SW7 5BD, UK.
Sacko M; Laboratory of Parasitology, Institut National de Recerche en Sante Publique, Bamako, Mali.
Volckaert FAM; Laboratory of Biodiversity and Evolutionary Genomics, Department of Biology, KU Leuven, Ch. Deberiotstraat 32, B-3000 Leuven, Belgium.
Polman K; Unit of Medical Helminthology, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.
Huyse T; Laboratory of Biodiversity and Evolutionary Genomics, Department of Biology, KU Leuven, Ch. Deberiotstraat 32, B-3000 Leuven, Belgium; Department of Biology, Royal Museum for Central Africa, Leuvensesteenweg 13, B-3080 Tervuren, Belgium. Electronic address: .
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Źródło :
International journal for parasitology [Int J Parasitol] 2019 Dec; Vol. 49 (13-14), pp. 1039-1048. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Variation*
Cattle Diseases/*parasitology
Chimera/*classification
Schistosoma/*classification
Schistosoma/*isolation & purification
Schistosomiasis/*parasitology
Schistosomiasis/*veterinary
Animals ; Cattle ; Cattle Diseases/epidemiology ; Chimera/genetics ; DNA, Mitochondrial/chemistry ; DNA, Mitochondrial/genetics ; Disease Outbreaks ; Electron Transport Complex IV/genetics ; Humans ; Microsatellite Repeats ; Schistosoma/genetics ; Schistosomiasis/epidemiology ; Senegal/epidemiology ; Sequence Analysis, DNA
Czasopismo naukowe

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