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Wyświetlanie 1-40 z 40
Tytuł :
Phthalyl starch nanoparticles as prebiotics enhanced nisin production in Lactococcus lactis through the induction of mild stress in probiotics.
Autorzy :
Hong L; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea.; Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry, College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin, China.
Cho CS; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea.; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Kim WS; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea.
Choi YJ; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea.; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Kang SK; Institute of Green-Bio Science & Technology, Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang, Gangwon-do, Republic of Korea.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2021 Feb; Vol. 130 (2), pp. 439-449. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Lactococcus lactis/*metabolism
Nanoparticles/*metabolism
Nisin/*biosynthesis
Probiotics/*metabolism
Starch/*metabolism
Anti-Bacterial Agents/pharmacology ; Listeria monocytogenes/drug effects ; Nanoparticles/chemistry ; Prebiotics ; Probiotics/pharmacology ; Salmonella/growth & development ; Starch/chemistry ; Stress, Physiological/genetics
SCR Organism :
Salmonella enterica subsp. enterica
Czasopismo naukowe
Tytuł :
Elicitation of Th1/Th2 related responses in mice by chitosan nanoparticles loaded with Brucella abortus malate dehydrogenase, outer membrane proteins 10 and 19.
Autorzy :
Shim S; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea.
Soh SH; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea.
Im YB; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea.
Park HE; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea.
Cho CS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea.
Kim S; College of Veterinary Medicine, Gyeongsang National University, Jinju, 52828, South Korea.
Yoo HS; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, 08826, South Korea. Electronic address: .
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Źródło :
International journal of medical microbiology : IJMM [Int J Med Microbiol] 2020 Jan; Vol. 310 (1), pp. 151362. Date of Electronic Publication: 2019 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Bacterial/*blood
Bacterial Outer Membrane Proteins/*immunology
Brucella Vaccine/*immunology
Malate Dehydrogenase/*immunology
Nanoparticles/*administration & dosage
Th1 Cells/*immunology
Th2 Cells/*immunology
Animals ; Bacterial Outer Membrane Proteins/administration & dosage ; Brucella Vaccine/administration & dosage ; Brucella abortus/immunology ; Brucellosis/prevention & control ; Chitosan/administration & dosage ; Cytokines/immunology ; Female ; Immunization ; Immunogenicity, Vaccine ; Immunoglobulin G/blood ; Interferon-gamma/blood ; Malate Dehydrogenase/administration & dosage ; Mice ; Mice, Inbred BALB C ; Nanoparticles/chemistry ; Recombinant Proteins/immunology
Czasopismo naukowe
Tytuł :
Novel production of natural bacteriocin via internalization of dextran nanoparticles into probiotics.
Autorzy :
Kim WS; Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Han GG; Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Hong L; Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Kang SK; Institute of Green-Bio Science & Technology, Seoul National University, Pyeongchang, Gangwon-do 25354, Republic of Korea. Electronic address: .
Shokouhimehr M; Department of Materials Science and Engineering, Research Institute of Advanced Materials, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Choi YJ; Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Cho CS; Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2019 Oct; Vol. 218, pp. 119360. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Prebiotics*
Anti-Infective Agents/*chemistry
Dextrans/*chemistry
Nanoparticles/*chemistry
Probiotics/*chemistry
Anti-Infective Agents/pharmacology ; Pediococcus/drug effects ; Peptides/chemistry
Czasopismo naukowe
Tytuł :
In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells.
Autorzy :
Detampel P; Department of Cell Biology and Anatomy, University of Calgary, Calgary, Canada.
Ganguly A; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.; Department of Surgery, University of Michigan at Ann Arbor, Ann Arbor, Michigan, United States of America.
Tehranian S; Department of Chemical and Petroleum Engineering, University of Calgary, Calgary, Canada.
Green F; Department Pathology & Laboratory Medicine, University of Calgary, Calgary, Canada.
Singha S; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.; The Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada.
Santamaria P; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.; The Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada.
Jeje AA; Department of Chemical and Petroleum Engineering, University of Calgary, Calgary, Canada.
Cho CS; Department of Surgery, University of Michigan at Ann Arbor, Ann Arbor, Michigan, United States of America.
Petri B; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.; The Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada.
Amrein MW; Department of Cell Biology and Anatomy, University of Calgary, Calgary, Canada.
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Źródło :
PloS one [PLoS One] 2019 Sep 30; Vol. 14 (9), pp. e0223339. Date of Electronic Publication: 2019 Sep 30 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alveolar Epithelial Cells/*metabolism
Fluorocarbons/*pharmacokinetics
Nanoparticles/*administration & dosage
Silicon Dioxide/*pharmacokinetics
Transcytosis/*physiology
A549 Cells ; Administration, Inhalation ; Alveolar Epithelial Cells/cytology ; Alveolar Epithelial Cells/drug effects ; Animals ; Female ; Humans ; Intravital Microscopy ; Kidney/blood supply ; Kidney/metabolism ; Mice ; Mice, Inbred C57BL ; Particle Size ; Spleen/blood supply ; Spleen/metabolism ; Trachea/blood supply ; Trachea/cytology ; Trachea/drug effects ; Trachea/metabolism
Czasopismo naukowe
Tytuł :
Intranasal immunization with pneumococcal surface protein A in the presence of nanoparticle forming polysorbitol transporter adjuvant induces protective immunity against the Streptococcus pneumoniae infection.
Autorzy :
Kye YC; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Park SM; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea; Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Shim BS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea; Department of Molecular Vaccinology, Laboratory Science Division, International Vaccine Institute, Seoul, Republic of Korea.
Firdous J; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Kim G; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea; Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea.
Kim HW; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Ju YJ; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Kim CG; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Cho CS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Kim DW; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Republic of Korea.
Cho JH; Academy of Immunology & Microbiology, Institute for Basic Science, Pohang, Republic of Korea.
Song MK; Department of Molecular Vaccinology, Laboratory Science Division, International Vaccine Institute, Seoul, Republic of Korea.
Han SH; Department of Oral Microbiology and Immunology, DRI and BK21 Program, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Yun CH; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea; Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea; Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang, Gangwon-do, Republic of Korea. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2019 May; Vol. 90, pp. 362-372. Date of Electronic Publication: 2019 Mar 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Bacterial*/chemistry
Antigens, Bacterial*/immunology
Antigens, Bacterial*/pharmacology
Bacterial Proteins*/chemistry
Bacterial Proteins*/immunology
Bacterial Proteins*/pharmacology
Pneumococcal Infections*/immunology
Pneumococcal Infections*/pathology
Pneumococcal Infections*/prevention & control
Pneumococcal Vaccines*/immunology
Pneumococcal Vaccines*/pharmacology
Vaccination*
Nanoparticles/*chemistry
Streptococcus pneumoniae/*immunology
Adjuvants, Immunologic/chemistry ; Adjuvants, Immunologic/pharmacology ; Administration, Intranasal ; Animals ; Female ; Mice ; Mice, Inbred BALB C ; Nanoparticles/therapeutic use
Czasopismo naukowe
Tytuł :
Induction of Th2-related immune responses and production of systemic IgA in mice intranasally immunized with Brucella abortus malate dehydrogenase loaded chitosan nanoparticles.
Autorzy :
Soh SH; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Shim S; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Im YB; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Park HT; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Cho CS; Department of Agricultural Biotechnology & Research Institute for Agriculture & Life Sciences, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
Yoo HS; Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: .
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Źródło :
Vaccine [Vaccine] 2019 Mar 14; Vol. 37 (12), pp. 1554-1564. Date of Electronic Publication: 2019 Feb 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chitosan*/chemistry
Nanoparticles*/chemistry
Brucella abortus/*immunology
Brucellosis/*prevention & control
Immunoglobulin A/*immunology
Malate Dehydrogenase/*immunology
Th2 Cells/*immunology
Administration, Intranasal ; Animals ; Brucella Vaccine/administration & dosage ; Brucella Vaccine/immunology ; Brucella abortus/enzymology ; Cell Line ; Cytokines/biosynthesis ; Enzyme-Linked Immunospot Assay ; Humans ; Immunity, Mucosal ; Immunization ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Malate Dehydrogenase/administration & dosage ; Malate Dehydrogenase/chemistry ; Mice ; Recombinant Proteins ; Th2 Cells/metabolism
Czasopismo naukowe
Tytuł :
Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel model.
Autorzy :
Ahn J; School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 08826, South Korea; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, North Ave NW, Atlanta, GA 30332, USA.
Cho CS; Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 08826, South Korea.
Cho SW; Ulsan National Institute of Science and Technology, Ulsan 44914, South Korea.
Kang JH; Ulsan National Institute of Science and Technology, Ulsan 44914, South Korea.
Kim SY; Department of Biophysics and Chemical Biology, Seoul National University, Seoul, South Korea.
Min DH; Department of Chemistry, Seoul National University, Seoul, South Korea.
Song JM; College of Pharmacy, Seoul National University, Seoul 08826, South Korea.
Park TE; Ulsan National Institute of Science and Technology, Ulsan 44914, South Korea. Electronic address: .
Jeon NL; School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 08826, South Korea. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2018 Aug; Vol. 76, pp. 154-163. Date of Electronic Publication: 2018 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Cardiovascular*
Human Umbilical Vein Endothelial Cells/*metabolism
Microvessels/*metabolism
Nanoparticles/*adverse effects
Oxidative Stress/*drug effects
Pericytes/*metabolism
Polyethyleneimine/*administration & dosage
Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Microvessels/pathology ; Nanoparticles/chemistry ; Pericytes/pathology ; Polyethyleneimine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Nanoparticle-Based Phototriggered Cancer Immunotherapy and Its Domino Effect in the Tumor Microenvironment.
Autorzy :
Rajendrakumar SK; Department of Biomedical Science and BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University , Chonnam National University Medical School , Gwangju 61469 , South Korea.
Uthaman S; Department of Polymer Science and Engineering , Chungnam National University , 99 Daehak-ro , Yuseong-gu, Daejeon 34134 , South Korea.
Cho CS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences , Seoul National University , Seoul 08826 , South Korea.
Park IK; Department of Biomedical Science and BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University , Chonnam National University Medical School , Gwangju 61469 , South Korea.
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Źródło :
Biomacromolecules [Biomacromolecules] 2018 Jun 11; Vol. 19 (6), pp. 1869-1887. Date of Electronic Publication: 2018 Apr 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunotherapy/*methods
Nanoparticles/*therapeutic use
Neoplasms/*therapy
Phototherapy/*methods
Tumor Microenvironment/*immunology
Animals ; Antineoplastic Agents, Immunological/administration & dosage ; Antineoplastic Agents, Immunological/pharmacology ; Humans ; Immunotherapy/instrumentation ; Light ; Nanoparticles/chemistry ; Neoplasms/immunology ; Neoplasms/pathology ; Photochemotherapy/instrumentation ; Photochemotherapy/methods ; Phototherapy/instrumentation ; Tumor Microenvironment/drug effects
Czasopismo naukowe
Tytuł :
A New Method of Producing a Natural Antibacterial Peptide by Encapsulated Probiotics Internalized with Inulin Nanoparticles as Prebiotics.
Autorzy :
Cui LH; Department of Animal Science, College of Agriculture Science, Yanbian University, Yanji, Jilin 133002, P.R. China.; Co-Innovation Center of Beef Cattle Science and Industry Technology, Yanbian University, Yanji, Jilin 133002, P.R. China.
Yan CG; Department of Animal Science, College of Agriculture Science, Yanbian University, Yanji, Jilin 133002, P.R. China.; Co-Innovation Center of Beef Cattle Science and Industry Technology, Yanbian University, Yanji, Jilin 133002, P.R. China.
Li HS; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Kim WS; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Hong L; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Kang SK; Institute of Green-Bio Science and Technology, Seoul National University, Pyeongchang 25354, Republic of Korea.
Choi YJ; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Cho CS; Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea.
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Źródło :
Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2018 Apr 28; Vol. 28 (4), pp. 510-519.
Typ publikacji :
Journal Article
MeSH Terms :
Inulin/*pharmacology
Nanoparticles/*chemistry
Peptides/*pharmacology
Prebiotics/*microbiology
Probiotics/*pharmacology
Alginates ; Animals ; Anti-Bacterial Agents/administration & dosage ; Antibiosis ; Capsules/pharmacology ; Chitosan ; Coculture Techniques ; Drug Combinations ; Fatty Acids, Volatile/analysis ; Glucuronic Acid ; Hexuronic Acids ; Inulin/analysis ; Inulin/chemistry ; Inulin/isolation & purification ; Particle Size ; Pediocins/pharmacology ; Pediococcus acidilactici/physiology ; Peptides/administration & dosage ; Probiotics/administration & dosage ; Salmonella/drug effects
Czasopismo naukowe
Tytuł :
A new way of producing pediocin in Pediococcus acidilactici through intracellular stimulation by internalized inulin nanoparticles.
Autorzy :
Kim WS; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Lee JY; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Singh B; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.; Research Institute for Bioscience and Biotechnology, Kathmandu, 44600, Nepal.
Maharjan S; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.; Research Institute for Bioscience and Biotechnology, Kathmandu, 44600, Nepal.
Hong L; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Lee SM; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Cui LH; Co-Innovation Center of Beef Cattle Science and Industry Technology, Yanbian University, Yanji, Jilin, 133002, P. R. China.
Lee KJ; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Kim G; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.
Yun CH; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea.; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Kang SK; Institute of Green-Bio Science & Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, Republic of Korea.
Choi YJ; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea. .; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea. .
Cho CS; Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826, Republic of Korea. .; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2018 Apr 12; Vol. 8 (1), pp. 5878. Date of Electronic Publication: 2018 Apr 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Infective Agents/*administration & dosage
Inulin/*chemistry
Nanoparticles/*chemistry
Pediocins/*pharmacology
Anti-Infective Agents/chemistry ; Cytoplasm/drug effects ; Cytoplasm/genetics ; Gene Expression Regulation/drug effects ; Humans ; Inulin/pharmacology ; Listeria monocytogenes ; Pediocins/biosynthesis ; Pediocins/genetics ; Pediococcus acidilactici/chemistry ; Probiotics/chemistry ; Probiotics/pharmacology
Czasopismo naukowe
Tytuł :
Targeted delivery of vaccine to dendritic cells by chitosan nanoparticles conjugated with a targeting peptide ligand selected by phage display technique.
Autorzy :
Jung SN; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, 151-921, Korea.
Kang SK
Yeo GH
Li HY
Jiang T
Nah JW
Bok JD
Cho CS
Choi YJ
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Źródło :
Macromolecular bioscience [Macromol Biosci] 2015 Mar; Vol. 15 (3), pp. 395-404. Date of Electronic Publication: 2014 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Delivery Systems*
Cell Surface Display Techniques/*methods
Chitosan/*chemistry
Dendritic Cells/*metabolism
Nanoparticles/*chemistry
Peptides/*chemistry
Vaccines/*immunology
Amino Acid Sequence ; Animals ; Antibody Specificity ; Bone Marrow Cells/cytology ; Cell Differentiation ; Cell Line ; Cell Separation ; Dendritic Cells/cytology ; Female ; Ligands ; Mice ; Mice, Inbred BALB C ; Molecular Sequence Data ; Ovalbumin/metabolism ; Phenotype ; Proton Magnetic Resonance Spectroscopy ; Reproducibility of Results ; Solubility ; Water
Czasopismo naukowe
Tytuł :
Formulation of glutathione responsive anti-proliferative nanoparticles from thiolated Akt1 siRNA and disulfide-crosslinked PEI for efficient anti-cancer gene therapy.
Autorzy :
Muthiah M; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea.
Che HL; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea.
Kalash S; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea.
Jo J; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea.
Choi SY; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea.
Kim WJ; Department of Chemistry, Pohang University of Science and Technology, Pohang 790-784, South Korea.
Cho CS; Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, South Korea.
Lee JY; School of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 500-712, South Korea.
Park IK; Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-757, South Korea. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2015 Feb 01; Vol. 126, pp. 322-7. Date of Electronic Publication: 2014 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Therapy*
Disulfides/*chemistry
Glutathione/*chemistry
Nanoparticles/*chemistry
Polyethyleneimine/*chemistry
Proto-Oncogene Proteins c-akt/*genetics
RNA, Small Interfering/*chemistry
Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Colonic Neoplasms/therapy ; Cross-Linking Reagents/chemistry ; Disease Models, Animal ; Mice ; Mice, Inbred BALB C ; Polyethyleneimine/chemical synthesis ; Proto-Oncogene Proteins c-akt/biosynthesis ; RNA, Small Interfering/genetics ; RNA, Small Interfering/therapeutic use ; Sulfhydryl Compounds/chemistry
Czasopismo naukowe
Tytuł :
Nanoparticle-mediated delivery of siRNA for effective lung cancer therapy.
Autorzy :
Kim YD; Department of Molecular Genetics, School of Dentistry, Seoul National University, Seoul 110-749, Republic of Korea.
Park TE
Singh B
Maharjan S
Choi YJ
Choung PH
Arote RB
Cho CS
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Źródło :
Nanomedicine (London, England) [Nanomedicine (Lond)] 2015; Vol. 10 (7), pp. 1165-88.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
RNA Interference*
Lung Neoplasms/*therapy
Nanoparticles/*chemistry
RNA, Small Interfering/*administration & dosage
RNA, Small Interfering/*therapeutic use
RNAi Therapeutics/*methods
Animals ; Humans ; Lipids/chemistry ; Lung/metabolism ; Lung/pathology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Polymers/chemistry
Czasopismo naukowe
Tytuł :
Induction of long-term immunity against respiratory syncytial virus glycoprotein by an osmotic polymeric nanocarrier.
Autorzy :
Firdous J; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea; World Class University Biomodulation Major & Center for Food and Bioconvergence, Seoul National University, Seoul 151-742, Republic of Korea.
Islam MA; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea; World Class University Biomodulation Major & Center for Food and Bioconvergence, Seoul National University, Seoul 151-742, Republic of Korea; Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Park SM; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea; World Class University Biomodulation Major & Center for Food and Bioconvergence, Seoul National University, Seoul 151-742, Republic of Korea.
Cheon IS; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea; Laboratory Science Division, International Vaccine Institute, Seoul 151-919, Republic of Korea.
Shim BS; Laboratory Science Division, International Vaccine Institute, Seoul 151-919, Republic of Korea.
Yoon HS; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
Song M; Laboratory Science Division, International Vaccine Institute, Seoul 151-919, Republic of Korea.
Chang J; Division of Life and Pharmaceutical Sciences, Center for Cell Signaling and Drug Discovery Research, Ewha Womans University, Seoul 120-750, Republic of Korea.
Choi YJ; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
Park YM; Department of Immunology & Laboratory of Dendritic Cell Differentiation & Regulation, School of Medicine, Konkuk University, Chungju 380-701, Republic of Korea.
Boraschi D; Institute of Protein Biochemistry, Consiglio Nazionale delle Ricerche, Via P. Castellino111, 80131 Napoli, Italy.
Han SH; Department of Oral Microbiology and Immunology & DRI, School of Dentistry, Seoul National University, Seoul 110-740, Republic of Korea.
Cho CS; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea. Electronic address: .
Yun CH; Department of Agricultural Biotechnology & Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea; World Class University Biomodulation Major & Center for Food and Bioconvergence, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2014 Nov; Vol. 10 (11), pp. 4606-4617. Date of Electronic Publication: 2014 Aug 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycoproteins/*immunology
Immunity/*drug effects
Nanoparticles/*chemistry
Polyesters/*chemistry
Polyethyleneimine/*analogs & derivatives
Respiratory Syncytial Viruses/*immunology
Viral Proteins/*immunology
Animals ; Cell Line ; Cell Shape/drug effects ; Female ; Fluorescein-5-isothiocyanate ; Humans ; Macrophages/drug effects ; Macrophages/ultrastructure ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Nanoparticles/ultrastructure ; Osmolar Concentration ; Phagocytosis/drug effects ; Polyesters/chemical synthesis ; Polyesters/toxicity ; Polyethyleneimine/chemical synthesis ; Polyethyleneimine/chemistry ; Polyethyleneimine/toxicity ; Respiratory Syncytial Viruses/drug effects
Czasopismo naukowe
Tytuł :
Targeted gene delivery via N-acetylglucosamine receptor mediated endocytosis.
Autorzy :
Singh B
Maharjan S
Kim YK
Jiang T
Islam MA
Kang SK
Cho MH
Choi YJ
Cho CS
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Źródło :
Journal of nanoscience and nanotechnology [J Nanosci Nanotechnol] 2014 Nov; Vol. 14 (11), pp. 8356-64.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylglucosamine/*metabolism
Endocytosis/*physiology
Nanoparticles/*chemistry
Receptors, N-Acetylglucosamine/*metabolism
Transfection/*methods
Acetylglucosamine/chemistry ; Cell Line, Transformed ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Stability ; Humans ; Nanoparticles/toxicity ; Polymers/chemistry ; Vimentin/metabolism
Czasopismo naukowe
Tytuł :
Selective transfection with osmotically active sorbitol modified PEI nanoparticles for enhanced anti-cancer gene therapy.
Autorzy :
Nguyen KC; Department of Biochemistry, Chonnam National University Medical School, Gwangju 501-746, South Korea; BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Chonnam National University Medical School, Gwangju 501-746, South Korea.
Muthiah M; Department of Biomedical Science and Chonnam National University Medical School, Gwangju 501-746, South Korea; BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Chonnam National University Medical School, Gwangju 501-746, South Korea.
Islam MA; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, South Korea.
Kalash RS; Department of Biomedical Science and Chonnam National University Medical School, Gwangju 501-746, South Korea.
Cho CS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, South Korea.
Park H; School of Integrative Engineering, Chung-Ang University, Dongjak-gu, Seoul 156-756, South Korea.
Lee IK; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Jeollanamdo 519-763, South Korea.
Kim HJ; Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Jeollanamdo 519-763, South Korea.
Park IK; Department of Biomedical Science and Chonnam National University Medical School, Gwangju 501-746, South Korea; BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Chonnam National University Medical School, Gwangju 501-746, South Korea. Electronic address: .
Cho KA; Department of Biochemistry, Chonnam National University Medical School, Gwangju 501-746, South Korea; BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University, Chonnam National University Medical School, Gwangju 501-746, South Korea. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2014 Jul 01; Vol. 119, pp. 126-36. Date of Electronic Publication: 2014 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Transfer Techniques*
Nanoparticles/*chemistry
Plasmids/*metabolism
Polyesters/*chemistry
Polyethyleneimine/*analogs & derivatives
Tumor Suppressor Protein p53/*genetics
Animals ; Apoptosis ; Caveolae/metabolism ; Cell Line, Tumor ; Endocytosis ; Gene Expression ; Genetic Therapy ; Humans ; Lipids/chemistry ; Luciferases/genetics ; Luciferases/metabolism ; Macrophages, Peritoneal/cytology ; Macrophages, Peritoneal/metabolism ; Mice ; Particle Size ; Polyethyleneimine/chemistry ; Primary Cell Culture ; Static Electricity ; Transgenes ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
Nanoparticle-mediated delivery of therapeutic genes: focus on miRNA therapeutics.
Autorzy :
Muthiah M; Chonnam National University Medical School, Research Institute of Medical Sciences, Department of Biomedical Science, Gwangju, South Korea. />Park IK
Cho CS
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Źródło :
Expert opinion on drug delivery [Expert Opin Drug Deliv] 2013 Sep; Vol. 10 (9), pp. 1259-73. Date of Electronic Publication: 2013 Jul 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Delivery Systems*
Genetic Therapy*
MicroRNAs/*genetics
Nanoparticles/*chemistry
Animals ; Humans ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Mannose-poly(ethylene glycol)-linked SPION targeted to antigen presenting cells for magnetic resonance imaging on lymph node.
Autorzy :
Muthiah M; Department of Biomedical Sciences and Center for Biomedical Human Resources (BK-21 project), Chonnam National University Medical School, Gwangju 501-757, South Korea.
Vu-Quang H
Kim YK
Rhee JH
Kang SH
Jun SY
Choi YJ
Jeong YY
Cho CS
Park IK
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2013 Feb 15; Vol. 92 (2), pp. 1586-95. Date of Electronic Publication: 2012 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Magnetic Resonance Imaging*
Antigen-Presenting Cells/*metabolism
Ferric Compounds/*chemistry
Lymph Nodes/*cytology
Mannose/*chemistry
Nanoparticles/*chemistry
Polyethylene Glycols/*chemistry
Animals ; Biocompatible Materials/chemistry ; Biocompatible Materials/metabolism ; Lectins, C-Type/metabolism ; Magnets/chemistry ; Male ; Mannans/chemistry ; Mannose-Binding Lectins/metabolism ; Mice ; Rats ; Receptors, Cell Surface/metabolism
Czasopismo naukowe
Tytuł :
Folate-PEG-superparamagnetic iron oxide nanoparticles for lung cancer imaging.
Autorzy :
Yoo MK; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, South Korea.
Park IK
Lim HT
Lee SJ
Jiang HL
Kim YK
Choi YJ
Cho MH
Cho CS
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Źródło :
Acta biomaterialia [Acta Biomater] 2012 Aug; Vol. 8 (8), pp. 3005-13. Date of Electronic Publication: 2012 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dextrans*/chemical synthesis
Dextrans*/chemistry
Dextrans*/toxicity
Magnetite Nanoparticles*/chemistry
Magnetite Nanoparticles*/toxicity
Nanoparticles*/chemistry
Nanoparticles*/toxicity
Nanoparticles*/ultrastructure
Polyethylene Glycols*/chemical synthesis
Polyethylene Glycols*/chemistry
Polyethylene Glycols*/toxicity
Diagnostic Imaging/*methods
Folic Acid/*analogs & derivatives
Lung Neoplasms/*diagnosis
Animals ; Biological Assay ; Cell Death/drug effects ; Flow Cytometry ; Folic Acid/chemical synthesis ; Folic Acid/chemistry ; Folic Acid/toxicity ; Lung Neoplasms/pathology ; Magnetic Resonance Spectroscopy ; Male ; Mice ; Microscopy, Confocal ; Particle Size ; Spectroscopy, Fourier Transform Infrared ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Intranasal immunization with plasmid DNA encoding spike protein of SARS-coronavirus/polyethylenimine nanoparticles elicits antigen-specific humoral and cellular immune responses.
Autorzy :
Shim BS; Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
Park SM
Quan JS
Jere D
Chu H
Song MK
Kim DW
Jang YS
Yang MS
Han SH
Park YH
Cho CS
Yun CH
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Źródło :
BMC immunology [BMC Immunol] 2010 Dec 31; Vol. 11, pp. 65. Date of Electronic Publication: 2010 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*immunology
Immunity/*immunology
Immunization/*methods
Membrane Glycoproteins/*immunology
Nanoparticles/*chemistry
Plasmids/*immunology
Polyethyleneimine/*pharmacology
Viral Envelope Proteins/*immunology
Administration, Intranasal ; Animals ; Antibodies, Viral/immunology ; Antibody Formation/drug effects ; Antigens, Surface/immunology ; B-Lymphocytes/cytology ; B-Lymphocytes/drug effects ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; DNA/administration & dosage ; Dendritic Cells/cytology ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Dendritic Cells/virology ; Epitopes/immunology ; Immunity/drug effects ; Immunity, Cellular/drug effects ; Immunity, Cellular/immunology ; Immunity, Humoral/drug effects ; Immunity, Humoral/immunology ; Mice ; Mice, Inbred BALB C ; Plasmids/administration & dosage ; Spike Glycoprotein, Coronavirus ; T-Lymphocytes/cytology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/virology
Czasopismo naukowe
Tytuł :
Targeted delivery of chitosan nanoparticles to Peyer's patch using M cell-homing peptide selected by phage display technique.
Autorzy :
Yoo MK; School of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea.
Kang SK
Choi JH
Park IK
Na HS
Lee HC
Kim EB
Lee NK
Nah JW
Choi YJ
Cho CS
Pokaż więcej
Źródło :
Biomaterials [Biomaterials] 2010 Oct; Vol. 31 (30), pp. 7738-47. Date of Electronic Publication: 2010 Jul 24.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanoparticles*
Peptide Library*
Chitosan/*metabolism
Drug Carriers/*metabolism
Drug Delivery Systems/*methods
Eye Proteins/*metabolism
Peptide Fragments/*metabolism
Peyer's Patches/*metabolism
Amino Acid Sequence ; Animals ; Carbohydrate Conformation ; Carbohydrate Sequence ; Cell Line ; Chitosan/chemistry ; Drug Carriers/chemistry ; Eye Proteins/genetics ; Humans ; Materials Testing ; Molecular Sequence Data ; Molecular Structure ; Peptide Fragments/genetics ; Rats
Czasopismo naukowe
Tytuł :
Superparamagnetic iron oxide nanoparticles coated with mannan for macrophage targeting.
Autorzy :
Yoo MK; Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea.
Park IY
Kim IY
Park IK
Kwon JS
Jeong HJ
Jeong YY
Cho CS
Pokaż więcej
Źródło :
Journal of nanoscience and nanotechnology [J Nanosci Nanotechnol] 2008 Oct; Vol. 8 (10), pp. 5196-202.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanoparticles*
Ferric Compounds/*chemistry
Macrophages/*drug effects
Mannans/*chemistry
Animals ; Cell Line ; Mice ; Microscopy, Electron, Transmission
Czasopismo naukowe
Tytuł :
Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery.
Autorzy :
Park IY; School of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
Kim IY
Yoo MK
Choi YJ
Cho MH
Cho CS
Pokaż więcej
Źródło :
International journal of pharmaceutics [Int J Pharm] 2008 Jul 09; Vol. 359 (1-2), pp. 280-7. Date of Electronic Publication: 2008 Apr 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanoparticles*
Transfection*
DNA/*administration & dosage
Genetic Therapy/*methods
Animals ; Cell Line ; Cell Survival/drug effects ; Deoxyribonuclease I/metabolism ; Drug Delivery Systems ; HeLa Cells ; Humans ; Macrophages/metabolism ; Mannose/chemistry ; Mice ; Particle Size ; Plasmids/administration & dosage ; Polyethyleneimine/chemistry ; Porosity ; Silicon Dioxide/chemistry
Czasopismo naukowe
Tytuł :
Receptor-mediated gene delivery into antigen presenting cells using mannosylated chitosan/DNA nanoparticles.
Autorzy :
Kim TH; School of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea.
Nah JW
Cho MH
Park TG
Cho CS
Pokaż więcej
Źródło :
Journal of nanoscience and nanotechnology [J Nanosci Nanotechnol] 2006 Sep-Oct; Vol. 6 (9-10), pp. 2796-803.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Chitosan/*chemistry
DNA/*administration & dosage
DNA/*pharmacokinetics
Nanoparticles/*chemistry
Receptors, Cell Surface/*metabolism
Transfection/*methods
Animals ; Cells, Cultured ; DNA/chemistry ; Male ; Mannose/chemistry ; Mice ; Mice, Inbred ICR ; Nanoparticles/ultrastructure ; Particle Size
Czasopismo naukowe
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