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Tytuł:
Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model.
Autorzy:
Yeo HJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yoo KY; Department of Anatomy, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Jung BH; Department of Anatomy, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Eum WS; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 22; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Islets of Langerhans*/metabolism
Insulin-Secreting Cells*/metabolism
Mice ; Animals ; Humans ; Islet Amyloid Polypeptide/pharmacology ; Islet Amyloid Polypeptide/metabolism ; Apoptosis ; Amyloid/metabolism ; Disease Models, Animal ; Gene Products, tat/metabolism ; Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł:
Synergistic apoptosis by combination of metformin and an O-GlcNAcylation inhibitor in colon cancer cells.
Autorzy:
Lee DE; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Lee GY; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Lee HM; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Republic of Korea.
Lee SJ; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.
Kwon OS; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. .
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Źródło:
Cancer cell international [Cancer Cell Int] 2023 Jun 02; Vol. 23 (1), pp. 108. Date of Electronic Publication: 2023 Jun 02.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Protective Effects of PEP-1-GSTA2 Protein in Hippocampal Neuronal Cell Damage Induced by Oxidative Stress.
Autorzy:
Choi YJ; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Youn GS; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park JH; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo EJ; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kwon HJ; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee LR; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kim NY; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kwon SY; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Jung HY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Republic of Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Park J; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Han KH; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee KW; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park JK; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee CH; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 01; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Hippocampus*/metabolism
Oxidative Stress*
Animals ; Apoptosis ; Ischemia/metabolism ; Neurons/metabolism ; Reactive Oxygen Species/metabolism ; Glutathione Transferase/metabolism
Czasopismo naukowe
Tytuł:
Effects of Brain Factor‑7® against motor deficit and oxidative stress in a mouse model of MPTP‑induced Parkinson's disease.
Autorzy:
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Lee JW; Precision Medicine R&D Center, Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Kim SS; Precision Medicine R&D Center, Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan, Chungnam 31116, Republic of Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24289, Republic of Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24289, Republic of Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24289, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło:
Experimental and therapeutic medicine [Exp Ther Med] 2022 Aug 24; Vol. 24 (4), pp. 635. Date of Electronic Publication: 2022 Aug 24 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Metabolic Diseases and Risk of Head and Neck Cancer: A Cohort Study Analyzing Nationwide Population-Based Data.
Autorzy:
Choi SY; Department of Otolaryngology Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Cheong HK; Department of Internal Medicine, School of Medicine, Korea University, Ansan 15355, Korea.
Lee MK; Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Kang JW; Department of Otolaryngology Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Lee YC; Department of Otolaryngology Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Oh IH; Department of Preventive Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Eun YG; Department of Otolaryngology Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2022 Jul 04; Vol. 14 (13). Date of Electronic Publication: 2022 Jul 04.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Relationship between Neuronal Damage/Death and Astrogliosis in the Cerebral Motor Cortex of Gerbil Models of Mild and Severe Ischemia and Reperfusion Injury.
Autorzy:
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Lim SS; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim CH; Department of Neurosurgery, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Park Y; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 03; Vol. 23 (9). Date of Electronic Publication: 2022 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Ischemic Attack, Transient*/metabolism
Motor Cortex*/metabolism
Reperfusion Injury*/metabolism
Animals ; Astrocytes/metabolism ; Endothelial Cells/metabolism ; Gerbillinae/metabolism ; Glial Fibrillary Acidic Protein/metabolism ; Gliosis/metabolism ; Ischemia/metabolism ; Prosencephalon/metabolism
Czasopismo naukowe
Tytuł:
Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice.
Autorzy:
Her Y; Department of Dermatology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Gangwon 24289, Republic of Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology and Research Institute of Oral Sciences, College of Dentistry, Gangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Hong JK; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Lee JW; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim SS; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Mar; Vol. 25 (3). Date of Electronic Publication: 2022 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Pinus*/chemistry
Animals ; Cytokines/analysis ; Flavonoids/analysis ; Flavonoids/pharmacology ; Hair Follicle ; Mice ; Mice, Inbred C57BL ; Plant Bark/chemistry ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł:
Oncogenic Role of Exosomal Circular and Long Noncoding RNAs in Gastrointestinal Cancers.
Autorzy:
Yun BD; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Cipolla GA; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Berti FCB; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Malheiros D; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Oh TJ; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.; Genome-Based BioIT Convergence Institute, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choi SY; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 15; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Exosomes/*genetics
Gastrointestinal Neoplasms/*genetics
RNA, Circular/*genetics
RNA, Long Noncoding/*genetics
Cell Communication ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Tat-thioredoxin 1 reduces inflammation by inhibiting pro-inflammatory cytokines and modulating MAPK signaling.
Autorzy:
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.; Genesen Inc., Seoul 06181, Republic of Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Chungcheongnam 31066, Republic of Korea.
Yu YH; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło:
Experimental and therapeutic medicine [Exp Ther Med] 2021 Dec; Vol. 22 (6), pp. 1395. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
OSMI-1 Enhances TRAIL-Induced Apoptosis through ER Stress and NF-κB Signaling in Colon Cancer Cells.
Autorzy:
Lee SJ; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
Lee DE; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon OS; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 14; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Endoplasmic Reticulum Stress/*drug effects
Enzyme Inhibitors/*pharmacology
Signal Transduction/*drug effects
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Animals ; Cell Line, Tumor ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Endoribonucleases/antagonists & inhibitors ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Mice ; Mice, Nude ; N-Acetylglucosaminyltransferases/antagonists & inhibitors ; N-Acetylglucosaminyltransferases/metabolism ; NF-kappa B/metabolism ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Reactive Oxygen Species/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; TNF-Related Apoptosis-Inducing Ligand/therapeutic use ; Transcription Factor CHOP/metabolism ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł:
Anti-Cancer Activity of Phytochemicals Targeting Hypoxia-Inducible Factor-1 Alpha.
Autorzy:
Yun BD; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Oh TJ; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 10; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anticarcinogenic Agents/*therapeutic use
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Neoplasms/*drug therapy
Phytochemicals/*therapeutic use
Cell Survival/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Neoplasms/genetics ; Tumor Hypoxia/genetics
Czasopismo naukowe
Tytuł:
Populus tomentiglandulosa Extract Is Rich in Polyphenols and Protects Neurons, Astrocytes, and the Blood-Brain Barrier in Gerbil Striatum Following Ischemia-Reperfusion Injury.
Autorzy:
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongsangnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, North Gyeongsang, Korea.
Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan 31116, Chungnam, Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 07; Vol. 26 (18). Date of Electronic Publication: 2021 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*
Blood-Brain Barrier*
Gerbillinae*
Polyphenols*
Populus*
Animals ; Cell Death/drug effects ; Hippocampus/metabolism ; Neurons/drug effects ; Reperfusion Injury/drug therapy
Czasopismo naukowe
Tytuł:
Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia.
Autorzy:
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan, Gyeongnam 50510, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes/*metabolism
CA1 Region, Hippocampal/*metabolism
Gerbillinae/*metabolism
Neurons/*metabolism
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Brain Ischemia/pathology ; Cell Death ; Cerebral Cortex/metabolism ; Hippocampus/metabolism ; Ischemia/pathology ; Male ; Neurogenesis ; Prosencephalon ; Pyramidal Cells/metabolism ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł:
Neuroprotective and Anti-Inflammatory Effects of Pinus densiflora Bark Extract in Gerbil Hippocampus Following Transient Forebrain Ischemia.
Autorzy:
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han X; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 29; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Brain Ischemia/*drug therapy
Hippocampus/*drug effects
Neuroprotective Agents/*pharmacology
Pinus/*chemistry
Prosencephalon/*drug effects
Animals ; Anti-Inflammatory Agents/chemistry ; Brain Ischemia/genetics ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Gene Expression/drug effects ; Gerbillinae ; Hippocampus/metabolism ; Hippocampus/pathology ; Inflammation ; Interleukin-13/agonists ; Interleukin-13/genetics ; Interleukin-13/metabolism ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-4/agonists ; Interleukin-4/genetics ; Interleukin-4/metabolism ; Male ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Neuroprotective Agents/chemistry ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Proanthocyanidins/chemistry ; Proanthocyanidins/pharmacology ; Prosencephalon/metabolism ; Prosencephalon/pathology ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
The Hypoxia-Long Noncoding RNA Interaction in Solid Cancers.
Autorzy:
Son SW; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Yun BD; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Song MG; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 06; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hypoxia/*genetics
Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Tumor Microenvironment/*genetics
Animals ; Apoptosis/genetics ; Humans ; MicroRNAs/genetics
Czasopismo naukowe
Tytuł:
PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson's Disease.
Autorzy:
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Song Y; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 01; Vol. 26 (11). Date of Electronic Publication: 2021 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cysteamine/*analogs & derivatives
Dopaminergic Neurons/*cytology
Glutaredoxins/*administration & dosage
MAP Kinase Signaling System/*drug effects
Parkinson Disease/*drug therapy
Peptides/*chemistry
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects ; 1-Methyl-4-phenylpyridinium/adverse effects ; Animals ; Apoptosis/drug effects ; Cell Line ; Cysteamine/chemistry ; Disease Models, Animal ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Gene Expression Regulation/drug effects ; Glutaredoxins/chemistry ; Glutaredoxins/pharmacology ; Humans ; Male ; Mice ; Parkinson Disease/etiology ; Parkinson Disease/metabolism ; Substantia Nigra/chemistry
Czasopismo naukowe
Tytuł:
Ischemia-Reperfusion under Hyperthermia Increases Heme Oxygenase-1 in Pyramidal Neurons and Astrocytes with Accelerating Neuronal Loss in Gerbil Hippocampus.
Autorzy:
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Chungnam, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 12; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Injuries/*genetics
Heme Oxygenase-1/*genetics
Hippocampus/*metabolism
Reperfusion Injury/*genetics
Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Brain Injuries/metabolism ; Brain Injuries/pathology ; Gerbillinae/genetics ; Gerbillinae/metabolism ; Hippocampus/injuries ; Hippocampus/physiopathology ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł:
Therapeutic Effects of Decursin and Angelica gigas Nakai Root Extract in Gerbil Brain after Transient Ischemia via Protecting BBB Leakage and Astrocyte Endfeet Damage.
Autorzy:
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Angelica/*chemistry
Astrocytes/*pathology
Benzopyrans/*therapeutic use
Blood-Brain Barrier/*pathology
Butyrates/*therapeutic use
Ischemic Attack, Transient/*pathology
Plant Extracts/*therapeutic use
Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Benzopyrans/chemistry ; Benzopyrans/pharmacology ; Blood-Brain Barrier/drug effects ; Butyrates/chemistry ; Butyrates/pharmacology ; Gerbillinae ; Glial Fibrillary Acidic Protein/metabolism ; Glucose Transporter Type 1/metabolism ; Immunoglobulin G/metabolism ; Male ; Neuraminidase/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Plant Extracts/pharmacology ; Reference Standards ; Spatial Memory/drug effects
Czasopismo naukowe
Tytuł:
The Role of Noncoding RNAs in the Regulation of Anoikis and Anchorage-Independent Growth in Cancer.
Autorzy:
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 10; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anoikis*
Neoplasms/*genetics
RNA, Untranslated/*metabolism
Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/metabolism ; Neoplasms/physiopathology
Czasopismo naukowe
Tytuł:
Neuronal Death in the CNS Autonomic Control Center Comes Very Early after Cardiac Arrest and Is Not Significantly Attenuated by Prompt Hypothermic Treatment in Rats.
Autorzy:
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Kim YS; Department of Emergency Medicine, Samcheok Medical Center, Samcheok 25920, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park Y; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
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Źródło:
Cells [Cells] 2021 Jan 02; Vol. 10 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypothermia, Induced*
Autonomic Nervous System/*pathology
Central Nervous System/*pathology
Heart Arrest/*pathology
Neurons/*pathology
Animals ; Antigens, Nuclear/metabolism ; Cell Death ; Male ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Rats, Sprague-Dawley ; Survival Analysis ; Time Factors ; Rats
Czasopismo naukowe

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