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Tytuł :
Relationship between Neuronal Damage/Death and Astrogliosis in the Cerebral Motor Cortex of Gerbil Models of Mild and Severe Ischemia and Reperfusion Injury.
Autorzy :
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Lim SS; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim CH; Department of Neurosurgery, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Park Y; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 May 03; Vol. 23 (9). Date of Electronic Publication: 2022 May 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Laminar Shear Stress Enhances Cytosolic PINK1 Expression: Increased Mitophagic Sensitivity Toward Mitochondrial Dysfunction.
Autorzy :
Hong SG; Kinesiology, College of Public Health, Temple University, Philadelphia, PA.
Shin J; College of Public Health, Temple University, Philadelphia, PA.
Saredy J; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
Choi SY; College of Public Health, Temple University, Philadelphia, PA.
Wang H; Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
Park JY; Kinesiology, College of Public Health, Temple University, Philadelphia, PA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 May; Vol. 36 Suppl 1.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Astaxanthin Confers a Significant Attenuation of Hippocampal Neuronal Loss Induced by Severe Ischemia-Reperfusion Injury in Gerbils by Reducing Oxidative Stress.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee TK; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Marine drugs [Mar Drugs] 2022 Apr 14; Vol. 20 (4). Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries*
Neuroprotective Agents*/metabolism
Neuroprotective Agents*/pharmacology
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Gerbillinae/genetics ; Gerbillinae/metabolism ; Hippocampus ; Ischemia/metabolism ; Oxidative Stress ; Superoxide Dismutase-1/metabolism ; Xanthophylls
Czasopismo naukowe
Tytuł :
Flow-induced endothelial mitochondrial remodeling mitigates mitochondrial reactive oxygen species production and promotes mitochondrial DNA integrity in a p53-dependent manner.
Autorzy :
Shin J; From the Department of Kinesiology, Temple University, Philadelphia, PA, USA; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Hong SG; From the Department of Kinesiology, Temple University, Philadelphia, PA, USA.
Choi SY; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Rath ME; From the Department of Kinesiology, Temple University, Philadelphia, PA, USA.
Saredy J; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA; Center for Metabolic Disease Research, Temple University, Philadelphia, PA, USA.
Jovin DG; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Sayoc J; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Park HS; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Eguchi S; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Rizzo V; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Scalia R; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Wang H; Center for Metabolic Disease Research, Temple University, Philadelphia, PA, USA.
Houser SR; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA.
Park JY; From the Department of Kinesiology, Temple University, Philadelphia, PA, USA; Cardiovascular Research Center, Temple University, Philadelphia, PA, USA. Electronic address: .
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Źródło :
Redox biology [Redox Biol] 2022 Apr; Vol. 50, pp. 102252. Date of Electronic Publication: 2022 Jan 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Neuroprotective Effects of Purpurin Against Ischemic Damage via MAPKs, Bax, and Oxidative Stress Cascades in the Gerbil Hippocampus.
Autorzy :
Kim W; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Anatomy, College of Veterinary Medicine, and Veterinary Science Research Institute, Konkuk University, Seoul, 05030, South Korea.
Kwon HJ; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2022 Apr; Vol. 59 (4), pp. 2580-2592. Date of Electronic Publication: 2022 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Ischemic Attack, Transient*/metabolism
Neuroprotective Agents*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Anthraquinones ; Gerbillinae/metabolism ; Hippocampus/metabolism ; Hydrogen Peroxide/metabolism ; Ischemia/metabolism ; Oxidative Stress ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Pinus thunbergii bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice.
Autorzy :
Her Y; Department of Dermatology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Gangwon 24289, Republic of Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology and Research Institute of Oral Sciences, College of Dentistry, Gangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Hong JK; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Lee JW; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim SS; Famenity Co., Ltd., Uiwang, Gyeonggi 16006, Republic of Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2022 Mar; Vol. 25 (3). Date of Electronic Publication: 2022 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Pinus*/chemistry
Animals ; Cytokines/analysis ; Flavonoids/analysis ; Flavonoids/pharmacology ; Hair Follicle ; Mice ; Mice, Inbred C57BL ; Plant Bark/chemistry ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł :
Modified Transoral Endoscopic Thyroidectomy Technique Using Trapdoor Suspension Sutures.
Autorzy :
Kim SI; Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul, Korea.; Department of Otorhinolaryngology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.
Min HK; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Kang DW; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Choi SY; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Kang HJ; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Lee YC; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Eun YG; Department of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul, Korea.; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Ko SG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.
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Źródło :
Clinical and experimental otorhinolaryngology [Clin Exp Otorhinolaryngol] 2022 Feb; Vol. 15 (1), pp. 119-121. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Oncogenic Role of Exosomal Circular and Long Noncoding RNAs in Gastrointestinal Cancers.
Autorzy :
Yun BD; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Cipolla GA; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Berti FCB; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Malheiros D; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná, Curitiba 81531-990, Brazil.
Oh TJ; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.; Genome-Based BioIT Convergence Institute, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choi SY; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research, Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 15; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Exosomes/*genetics
Gastrointestinal Neoplasms/*genetics
RNA, Circular/*genetics
RNA, Long Noncoding/*genetics
Cell Communication ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Comparison Between Manual and Automated Analyses in Multichannel Intraluminal Impedance: pH Monitoring for Laryngopharyngeal Reflux.
Autorzy :
Kang HJ; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Park JM; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Choi SY; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Kim SI; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Lee YC; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Eun YG; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Ko SG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.
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Źródło :
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2022 Jan; Vol. 166 (1), pp. 128-132. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electric Impedance*
Esophageal pH Monitoring*
Laryngopharyngeal Reflux/*diagnosis
Adult ; Aged ; Cohort Studies ; Female ; Humans ; Laryngopharyngeal Reflux/complications ; Male ; Middle Aged ; Predictive Value of Tests ; Symptom Assessment
Czasopismo naukowe
Tytuł :
Tat-thioredoxin 1 reduces inflammation by inhibiting pro-inflammatory cytokines and modulating MAPK signaling.
Autorzy :
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.; Genesen Inc., Seoul 06181, Republic of Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Chungcheongnam 31066, Republic of Korea.
Yu YH; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
Experimental and therapeutic medicine [Exp Ther Med] 2021 Dec; Vol. 22 (6), pp. 1395. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Tat-p27 Ameliorates Neuronal Damage Reducing α-Synuclein and Inflammatory Responses in Motor Neurons After Spinal Cord Ischemia.
Autorzy :
Kim W; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Anatomy, College of Veterinary Medicine, and Veterinary Science Research Institute, Konkuk University, Seoul, 05030, South Korea.
Kwon HJ; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, 34134, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, 18450, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, 24253, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. .
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Źródło :
Neurochemical research [Neurochem Res] 2021 Dec; Vol. 46 (12), pp. 3123-3134. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Products, tat/*administration & dosage
Inflammation/*immunology
Motor Neuron Disease/*prevention & control
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Spinal Cord Ischemia/*complications
alpha-Synuclein/*antagonists & inhibitors
Animals ; Inflammation/drug therapy ; Inflammation/metabolism ; Lipid Peroxidation ; Male ; Motor Neuron Disease/etiology ; Motor Neuron Disease/metabolism ; Motor Neuron Disease/pathology ; Neurons/metabolism ; Neurons/pathology ; Oxidative Stress ; Rabbits ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Comparison of Neuronal Death, Blood-Brain Barrier Leakage and Inflammatory Cytokine Expression in the Hippocampal CA1 Region Following Mild and Severe Transient Forebrain Ischemia in Gerbils.
Autorzy :
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam, 31116, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan, Gyeongnam, 50510, Republic of Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon, 24252, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk, 38066, Republic of Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Gangwon, 24289, Republic of Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Gangwon, 24289, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon, 25457, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. .
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon, 24252, Republic of Korea. .
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Źródło :
Neurochemical research [Neurochem Res] 2021 Nov; Vol. 46 (11), pp. 2852-2866. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Blood-Brain Barrier/*metabolism
CA1 Region, Hippocampal/*metabolism
Cytokines/*biosynthesis
Inflammation Mediators/*metabolism
Ischemic Attack, Transient/*metabolism
Neurons/*metabolism
Animals ; Blood-Brain Barrier/pathology ; CA1 Region, Hippocampal/pathology ; Cell Death/physiology ; Cytokines/genetics ; Gene Expression ; Gerbillinae ; Ischemic Attack, Transient/genetics ; Ischemic Attack, Transient/pathology ; Male ; Neurons/pathology ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cells.
Autorzy :
Kim EA; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Hwang K; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim JE; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Ahn JY; Department of Molecular Cell Biology and Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon 16419, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chunchon 24252, Korea.
Yang SJ; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2021 Nov; Vol. 54 (11), pp. 557-562.
Typ publikacji :
Wiadomości
Periodyk
Tytuł :
OSMI-1 Enhances TRAIL-Induced Apoptosis through ER Stress and NF-κB Signaling in Colon Cancer Cells.
Autorzy :
Lee SJ; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
Lee DE; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon OS; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu 41566, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 14; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Endoplasmic Reticulum Stress/*drug effects
Enzyme Inhibitors/*pharmacology
Signal Transduction/*drug effects
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Animals ; Cell Line, Tumor ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Endoribonucleases/antagonists & inhibitors ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Mice ; Mice, Nude ; N-Acetylglucosaminyltransferases/antagonists & inhibitors ; N-Acetylglucosaminyltransferases/metabolism ; NF-kappa B/metabolism ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Reactive Oxygen Species/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; TNF-Related Apoptosis-Inducing Ligand/therapeutic use ; Transcription Factor CHOP/metabolism ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
Therapeutic Effects of Risperidone against Spinal Cord Injury in a Rat Model of Asphyxial Cardiac Arrest: A Focus on Body Temperature, Paraplegia, Motor Neuron Damage, and Neuroinflammation.
Autorzy :
Lee TK; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Jeollabuk, Korea.
Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan 31116, Chungnam, Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Hong S; Department of Surgery, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
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Źródło :
Veterinary sciences [Vet Sci] 2021 Oct 13; Vol. 8 (10). Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Utilization of an Intracellular Calcium Mobilization Assay for the Screening of Transduced FK506-Binding Proteins.
Autorzy :
Cha HJ; R&D Center, Lumieye Genetics Co., Ltd., Seoul, Korea.
Lee H; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.
Park SJ; R&D Center, Lumieye Genetics Co., Ltd., Seoul, Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
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Źródło :
Assay and drug development technologies [Assay Drug Dev Technol] 2021 Oct; Vol. 19 (7), pp. 442-452. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tacrolimus*/pharmacology
Tacrolimus Binding Proteins*/genetics
Tacrolimus Binding Proteins*/metabolism
Amino Acid Sequence ; Animals ; Calcium ; Carrier Proteins ; Humans
Czasopismo naukowe
Tytuł :
Anti-Cancer Activity of Phytochemicals Targeting Hypoxia-Inducible Factor-1 Alpha.
Autorzy :
Yun BD; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Oh TJ; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 10; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anticarcinogenic Agents/*therapeutic use
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Neoplasms/*drug therapy
Phytochemicals/*therapeutic use
Cell Survival/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Neoplasms/genetics ; Tumor Hypoxia/genetics
Czasopismo naukowe
Tytuł :
Populus tomentiglandulosa Extract Is Rich in Polyphenols and Protects Neurons, Astrocytes, and the Blood-Brain Barrier in Gerbil Striatum Following Ischemia-Reperfusion Injury.
Autorzy :
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongsangnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, North Gyeongsang, Korea.
Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan 31116, Chungnam, Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 07; Vol. 26 (18). Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes*
Blood-Brain Barrier*
Gerbillinae*
Polyphenols*
Populus*
Animals ; Cell Death/drug effects ; Hippocampus/metabolism ; Neurons/drug effects ; Reperfusion Injury/drug therapy
Czasopismo naukowe
Tytuł :
Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia.
Autorzy :
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan, Gyeongnam 50510, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*metabolism
CA1 Region, Hippocampal/*metabolism
Gerbillinae/*metabolism
Neurons/*metabolism
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Brain Ischemia/pathology ; Cell Death ; Cerebral Cortex/metabolism ; Hippocampus/metabolism ; Ischemia/pathology ; Male ; Neurogenesis ; Prosencephalon ; Pyramidal Cells/metabolism ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
Tat-CIAPIN1 protein prevents against cytokine-induced cytotoxicity in pancreatic RINm5F β-cells.
Autorzy :
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2021 Sep; Vol. 54 (9), pp. 458-463.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cytokines/*pharmacology
Gene Products, tat/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Recombinant Fusion Proteins/*metabolism
Caspase 3/metabolism ; Cell Line ; DNA Fragmentation/drug effects ; Gene Products, tat/metabolism ; Humans ; Insulin-Secreting Cells/cytology ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/genetics ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Extracts from the Leaves of Cissus verticillata Ameliorate High-Fat Diet-Induced Memory Deficits in Mice.
Autorzy :
Kim W; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy, College of Veterinary Medicine, Veterinary Science Research Institute, Konkuk University, Seoul 05030, Korea.
Kwon HJ; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Lim SS; Department of Food Science and Nutrition, Institute of Korean Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang BG; Department of Biochemistry, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Jo YB; Department of Convergence Technology, Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Yu DS; Department of Venture Management Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
Plants (Basel, Switzerland) [Plants (Basel)] 2021 Aug 31; Vol. 10 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Transduced Tat-PRAS40 prevents dopaminergic neuronal cell death through ROS inhibition and interaction with 14-3-3σ protein.
Autorzy :
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Kangneung-Wonju National University, Kangneung, 25457, South Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, 31538, South Korea.
Yu YH; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, 31538, South Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, 05505, South Korea.
Kwon OS; School of Life Sciences, College of Natural Sciences Kyungpook National University, Taegu, 41566, South Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon, 24253, South Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Aug 20; Vol. 172, pp. 418-429. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dopaminergic Neurons*
Oxidative Stress*
Animals ; Apoptosis ; Cell Death ; Mice ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
Neuroprotective and Anti-Inflammatory Effects of Pinus densiflora Bark Extract in Gerbil Hippocampus Following Transient Forebrain Ischemia.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han X; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 29; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Brain Ischemia/*drug therapy
Hippocampus/*drug effects
Neuroprotective Agents/*pharmacology
Pinus/*chemistry
Prosencephalon/*drug effects
Animals ; Anti-Inflammatory Agents/chemistry ; Brain Ischemia/genetics ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Gene Expression/drug effects ; Gerbillinae ; Hippocampus/metabolism ; Hippocampus/pathology ; Inflammation ; Interleukin-13/agonists ; Interleukin-13/genetics ; Interleukin-13/metabolism ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-4/agonists ; Interleukin-4/genetics ; Interleukin-4/metabolism ; Male ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Neuroprotective Agents/chemistry ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Proanthocyanidins/chemistry ; Proanthocyanidins/pharmacology ; Prosencephalon/metabolism ; Prosencephalon/pathology ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Changes in Cyclin D1, cdk4, and Their Associated Molecules in Ischemic Pyramidal Neurons in Gerbil Hippocampus after Transient Ischemia and Neuroprotective Effects of Ischemic Preconditioning by Keeping the Molecules in the Ischemic Neurons.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology and Research Institute of Oral Sciences, College of Dentistry, Kangnung-Wonju National University, Gangneung 25457, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Biology [Biology (Basel)] 2021 Jul 28; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Hypoxia-Long Noncoding RNA Interaction in Solid Cancers.
Autorzy :
Son SW; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Yun BD; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Song MG; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 06; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hypoxia/*genetics
Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Tumor Microenvironment/*genetics
Animals ; Apoptosis/genetics ; Humans ; MicroRNAs/genetics
Czasopismo naukowe
Tytuł :
Cissus verticillata Extract Decreases Neuronal Damage Induced by Oxidative Stress in HT22 Cells and Ischemia in Gerbils by Reducing the Inflammation and Phosphorylation of MAPKs.
Autorzy :
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy, College of Veterinary Medicine, Veterinary Science Research Institute, Konkuk University, Seoul 05030, Korea.
Kwon HJ; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Lim SS; Department of Food Science and Nutrition, Institute of Korean Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang BG; Department of Biochemistry, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Jo YB; Department of Convergence Technology, Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Yu DS; Department of Venture Management Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
Plants (Basel, Switzerland) [Plants (Basel)] 2021 Jun 15; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson's Disease.
Autorzy :
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Song Y; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 01; Vol. 26 (11). Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteamine/*analogs & derivatives
Dopaminergic Neurons/*cytology
Glutaredoxins/*administration & dosage
MAP Kinase Signaling System/*drug effects
Parkinson Disease/*drug therapy
Peptides/*chemistry
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects ; 1-Methyl-4-phenylpyridinium/adverse effects ; Animals ; Apoptosis/drug effects ; Cell Line ; Cysteamine/chemistry ; Disease Models, Animal ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Gene Expression Regulation/drug effects ; Glutaredoxins/chemistry ; Glutaredoxins/pharmacology ; Humans ; Male ; Mice ; Parkinson Disease/etiology ; Parkinson Disease/metabolism ; Substantia Nigra/chemistry
Czasopismo naukowe
Tytuł :
Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway.
Autorzy :
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan 31538, Republic of Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
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Źródło :
Biomolecules & therapeutics [Biomol Ther (Seoul)] 2021 May 01; Vol. 29 (3), pp. 321-330.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Neuroprotective Effects of Salicin in a Gerbil Model of Transient Forebrain Ischemia by Attenuating Oxidative Stress and Activating PI3K/Akt/GSK3β Pathway.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Lee TK; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Chungnam, Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Apr 20; Vol. 10 (4). Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ischemia-Reperfusion under Hyperthermia Increases Heme Oxygenase-1 in Pyramidal Neurons and Astrocytes with Accelerating Neuronal Loss in Gerbil Hippocampus.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Chungnam, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 12; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries/*genetics
Heme Oxygenase-1/*genetics
Hippocampus/*metabolism
Reperfusion Injury/*genetics
Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Brain Injuries/metabolism ; Brain Injuries/pathology ; Gerbillinae/genetics ; Gerbillinae/metabolism ; Hippocampus/injuries ; Hippocampus/physiopathology ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Therapeutic Effects of Decursin and Angelica gigas Nakai Root Extract in Gerbil Brain after Transient Ischemia via Protecting BBB Leakage and Astrocyte Endfeet Damage.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Angelica/*chemistry
Astrocytes/*pathology
Benzopyrans/*therapeutic use
Blood-Brain Barrier/*pathology
Butyrates/*therapeutic use
Ischemic Attack, Transient/*pathology
Plant Extracts/*therapeutic use
Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Benzopyrans/chemistry ; Benzopyrans/pharmacology ; Blood-Brain Barrier/drug effects ; Butyrates/chemistry ; Butyrates/pharmacology ; Gerbillinae ; Glial Fibrillary Acidic Protein/metabolism ; Glucose Transporter Type 1/metabolism ; Immunoglobulin G/metabolism ; Male ; Neuraminidase/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Plant Extracts/pharmacology ; Reference Standards ; Spatial Memory/drug effects
Czasopismo naukowe
Tytuł :
BDNF and Netrin-1 repression by C/EBPβ in the gut triggers Parkinson's disease pathologies, associated with constipation and motor dysfunctions.
Autorzy :
Ahn EH; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Kang SS; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Liu X; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Cao X; Department of Neurology, Union Hospital, Huazhong University of Science & Technology, Wuhan, China.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Musazzi L; Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.
Mehlen P; Apoptosis, Cancer and Development Laboratory, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR 5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
Ye K; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA. Electronic address: .
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Źródło :
Progress in neurobiology [Prog Neurobiol] 2021 Mar; Vol. 198, pp. 101905. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Parkinson Disease*
Animals ; Brain-Derived Neurotrophic Factor ; CCAAT-Enhancer-Binding Protein-beta ; Constipation ; Humans ; Inflammation ; Mice ; Netrin-1
Czasopismo naukowe
Tytuł :
Tyrosine Phosphorylation Modulates Peroxiredoxin-2 Activity in Normal and Diseased Red Cells.
Autorzy :
Mattè A; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Federti E; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Tibaldi E; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
Di Paolo ML; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
Bisello G; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biological Chemistry, University of Verona, 37134 Verona, Italy.
Bertoldi M; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biological Chemistry, University of Verona, 37134 Verona, Italy.
Carpentieri A; Department of Chemical Sciences, University Federico II of Napoli, 80126 Napoli, Italy.
Pucci P; Department of Chemical Sciences, University Federico II of Napoli, 80126 Napoli, Italy.; CEINGE Biotecnologie Avanzate, 80145 Napoli, Italy.
Iatchencko I; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Wilson AB; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Riccardi V; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Siciliano A; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Turrini F; Department of Oncology, University of Torino, 10124 Torino, Italy.
Kim DW; Department of Biomedical Sciences and Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Sciences and Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Brunati AM; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
De Franceschi L; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
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Źródło :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Feb 01; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Cerebral Coenurosis of a Long-Tailed Goral, Naemorhedus caudatus, in Korea.
Autorzy :
Ahn S; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Oh H; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Kim JT; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Kim HC; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
The Korean journal of parasitology [Korean J Parasitol] 2021 Feb; Vol. 59 (1), pp. 55-59. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Animals, Wild*
Artiodactyla*
Animal Diseases/*parasitology
Cysticercosis/*parasitology
Cysticercosis/*veterinary
Neglected Diseases/*parasitology
Neglected Diseases/*veterinary
Neurocysticercosis/*parasitology
Neurocysticercosis/*veterinary
Taenia/*isolation & purification
Taeniasis/*parasitology
Taeniasis/*veterinary
Animal Diseases/diagnostic imaging ; Animals ; Cerebrum/diagnostic imaging ; Cerebrum/parasitology ; Cysticercosis/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Neglected Diseases/diagnostic imaging ; Neurocysticercosis/diagnostic imaging ; Republic of Korea ; Taeniasis/diagnostic imaging ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Tat‑aldose reductase prevents dopaminergic neuronal cell death by inhibiting oxidative stress and MAPK activation.
Autorzy :
Cho SB; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan‑si, Chungcheong 31538, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
International journal of molecular medicine [Int J Mol Med] 2021 Feb; Vol. 47 (2), pp. 751-760. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Oxidative Stress*
Aldehyde Reductase/*metabolism
Dopaminergic Neurons/*enzymology
Extracellular Signal-Regulated MAP Kinases/*metabolism
Substantia Nigra/*enzymology
Aldehyde Reductase/genetics ; Animals ; Cell Death ; Cell Line, Tumor ; Enzyme Activation ; Extracellular Signal-Regulated MAP Kinases/genetics ; Humans ; MPTP Poisoning/enzymology ; MPTP Poisoning/genetics ; Male ; Mice
Czasopismo naukowe
Tytuł :
The Role of Noncoding RNAs in the Regulation of Anoikis and Anchorage-Independent Growth in Cancer.
Autorzy :
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 10; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anoikis*
Neoplasms/*genetics
RNA, Untranslated/*metabolism
Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/metabolism ; Neoplasms/physiopathology
Czasopismo naukowe
Tytuł :
Gynura procumbens Root Extract Ameliorates Ischemia-Induced Neuronal Damage in the Hippocampal CA1 Region by Reducing Neuroinflammation.
Autorzy :
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Yoo DY; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31151, Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
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Źródło :
Nutrients [Nutrients] 2021 Jan 08; Vol. 13 (1). Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
CA1 Region, Hippocampal/*drug effects
Inflammation/*drug therapy
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Plant Roots/*chemistry
Animals ; Body Weight ; Brain Ischemia/pathology ; Brain Ischemia/surgery ; CA1 Region, Hippocampal/pathology ; Cytokines ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Gerbillinae ; Hippocampus/drug effects ; Male ; Microglia ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Neuronal Death in the CNS Autonomic Control Center Comes Very Early after Cardiac Arrest and Is Not Significantly Attenuated by Prompt Hypothermic Treatment in Rats.
Autorzy :
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Kim YS; Department of Emergency Medicine, Samcheok Medical Center, Samcheok 25920, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park Y; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
Cells [Cells] 2021 Jan 02; Vol. 10 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypothermia, Induced*
Autonomic Nervous System/*pathology
Central Nervous System/*pathology
Heart Arrest/*pathology
Neurons/*pathology
Animals ; Antigens, Nuclear/metabolism ; Cell Death ; Male ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Rats, Sprague-Dawley ; Survival Analysis ; Time Factors
Czasopismo naukowe
Tytuł :
AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.
Autorzy :
Sari IN; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Yang YG; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.; Shenzhen Key Laboratory of Viral Oncology, The Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Wijaya YT; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Jun N; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Lee S; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Kim KS; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Bajaj J; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
Oehler VG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Kim SH; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Choi SY; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Park SH; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kim DW; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Reya T; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Han J; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Kwon HY; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea. .
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Źródło :
Oncogene [Oncogene] 2021 Jan; Vol. 40 (3), pp. 603-617. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Adenosylmethionine Decarboxylase/*metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*enzymology
Neoplasm Proteins/*metabolism
Neoplastic Stem Cells/*enzymology
Adenosylmethionine Decarboxylase/genetics ; Animals ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Mice ; Neoplasm Proteins/genetics ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus.
Autorzy :
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 14; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclin-Dependent Kinase Inhibitor p27/*metabolism
Hippocampus/*drug effects
Hippocampus/*metabolism
Animals ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Gerbillinae ; Humans ; Hydrogen Peroxide/pharmacology ; Microtubule-Associated Proteins/metabolism ; Oxidative Stress/drug effects ; Phospholipids/metabolism ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/pharmacology
Czasopismo naukowe
Tytuł :
Tat-indoleamine 2,3-dioxygenase 1 elicits neuroprotective effects on ischemic injury.
Autorzy :
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim HC; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon 24341, Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon 24341, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan 31538, Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Nov; Vol. 53 (11), pp. 582-587.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*physiopathology
Indoleamine-Pyrrole 2,3,-Dioxygenase/*pharmacology
Reperfusion Injury/*therapy
Animals ; Apoptosis/drug effects ; Cell Death/drug effects ; Cell Survival/drug effects ; Gerbillinae ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Ischemia/metabolism ; Male ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Reperfusion Injury/metabolism
Czasopismo naukowe
Tytuł :
N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons.
Autorzy :
Yang SJ; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Han AR; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi HR; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Hwang K; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim EA; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chunchon 24252, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Nov; Vol. 53 (10), pp. 527-532.
Typ publikacji :
Wiadomości
MeSH Terms :
Adamantane/*analogs & derivatives
Autophagy/*drug effects
Neurons/*metabolism
Thiazoles/*pharmacology
Adamantane/metabolism ; Adamantane/pharmacology ; Animals ; Antioxidants/pharmacology ; Autophagic Cell Death ; Autophagy/physiology ; Cerebral Cortex/metabolism ; Glutamic Acid/adverse effects ; Glutamic Acid/metabolism ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Neurons/drug effects ; Oxidative Stress/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Superoxide Dismutase/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Thiazoles/metabolism
Periodyk
Tytuł :
Participation of MicroRNAs in the Treatment of Cancer with Phytochemicals.
Autorzy :
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 14; Vol. 25 (20). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Gene Expression Regulation, Neoplastic/*drug effects
MicroRNAs/*genetics
Phytochemicals/*pharmacology
Animals ; Anticarcinogenic Agents/pharmacology ; Clinical Trials as Topic ; Genes, Tumor Suppressor/drug effects ; Humans ; Neoplasms/drug therapy ; Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Metformin ameliorates animal models of dermatitis.
Autorzy :
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Department of Cosmetics Engineering, Research Institute for Molecular-Targeted Drugs, Konkuk University, Seoul, 05029, South Korea.
An S; Department of Cosmetics Engineering, Research Institute for Molecular-Targeted Drugs, Konkuk University, Seoul, 05029, South Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Inflammopharmacology [Inflammopharmacology] 2020 Oct; Vol. 28 (5), pp. 1293-1300. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*drug effects
Dermatitis/*drug therapy
Enzyme Activators/*pharmacology
Metformin/*pharmacology
AMP-Activated Protein Kinases/metabolism ; Animals ; Collagen/metabolism ; Dermatitis/pathology ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Humans ; Male ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Skin/drug effects ; Skin/pathology ; Tetradecanoylphorbol Acetate
Czasopismo naukowe
Tytuł :
Fyn specifically Regulates the activity of red cell glucose-6-phosphate-dehydrogenase.
Autorzy :
Mattè A; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Lupo F; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Tibaldi E; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Di Paolo ML; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Federti E; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Carpentieri A; Dept of Chemical Sciences, University Federico II, Naples, Italy.
Pucci P; Dept of Chemical Sciences, University Federico II, Naples, Italy.
Brunati AM; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Cesaro L; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Turrini F; Dept of Oncology, University of Torino, Torino, Italy.
Gomez Manzo S; Laboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City, Mexico.
Choi SY; Institute of Bioscience and Biotechnology, Hallym University, Gangowo-do, South Korea.
Marcial Quino J; Consejo Nacional de Ciencia y Tecnology, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City, Mexico.
Kim DW; Institute of Bioscience and Biotechnology, Hallym University, Gangowo-do, South Korea.
Pantaleo A; Dept of Physiology, University of Sassari, Sassari, Italy.
Xiuli A; School of Life Sciences, Zhengzhou University, Zhengzhou, China; Laboratory of Membrane Biology, New York Blood Center, New York, NY, USA.
Iatcenko I; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Cappellini MD; Dept of Medicine, University of Milan, Milan, Italy.
Forni GL; Centro Della Microcitemia e Delle Anemie Congenite, Ospedale Galliera, Genova, Italy.
De Franceschi L; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy. Electronic address: .
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Źródło :
Redox biology [Redox Biol] 2020 Sep; Vol. 36, pp. 101639. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucosephosphate Dehydrogenase*
Glucosephosphate Dehydrogenase Deficiency*/genetics
Animals ; Erythrocytes ; Glucose-6-Phosphate ; Hemolysis ; Mice ; Proto-Oncogene Proteins c-fyn
Czasopismo naukowe
Tytuł :
Experimental Pretreatment with Chlorogenic Acid Prevents Transient Ischemia-Induced Cognitive Decline and Neuronal Damage in the Hippocampus through Anti-Oxidative and Anti-Inflammatory Effects.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gsangwon 24252, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Sim HJ; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457 Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Ryoo S; Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Park JH; Department of Anatomy, College of Oriental Medicine, Dongguk University-Gyeongju, Gyeongju, Gyeongbuk, 38066, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Aug 06; Vol. 25 (16). Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorogenic Acid/*pharmacology
Cognition/*drug effects
Hippocampus/*pathology
Ischemia/*pathology
Ischemia/*physiopathology
Neurons/*drug effects
Neurons/*pathology
Aldehydes/metabolism ; Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Hippocampus/drug effects ; Interleukin-2/metabolism ; Interleukin-4/metabolism ; Ischemia/metabolism ; Mice ; Neuroprotective Agents/pharmacology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Extracellular Vesicles (EVs) and Pancreatic Cancer: From the Role of EVs to the Interference with EV-Mediated Reciprocal Communication.
Autorzy :
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee JS; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kim TH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
Biomedicines [Biomedicines] 2020 Aug 03; Vol. 8 (8). Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis.
Autorzy :
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 03; Vol. 21 (9). Date of Electronic Publication: 2020 May 03.
Typ publikacji :
Journal Article
MeSH Terms :
Dermatitis, Allergic Contact/*drug therapy
Dopamine Antagonists/*therapeutic use
Perphenazine/*therapeutic use
Animals ; Cytokines/metabolism ; Dermatitis, Allergic Contact/etiology ; Dopamine Antagonists/pharmacology ; Immunoglobulin G/metabolism ; Mast Cells/drug effects ; Mast Cells/immunology ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Oxazolone/toxicity ; Perphenazine/pharmacology ; Tetradecanoylphorbol Acetate/toxicity ; Th2 Cells/drug effects ; Th2 Cells/immunology
Czasopismo naukowe
Tytuł :
Laminarin Pretreatment Provides Neuroprotection against Forebrain Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Neuroinflammation in Aged Gerbils.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457, Korea.
Shin MC; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Cho JH; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dancook University, Cheonan, Chungcheongnam 31116, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
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Źródło :
Marine drugs [Mar Drugs] 2020 Apr 15; Vol. 18 (4). Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
Glucans/*pharmacology
Inflammation/*metabolism
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Reperfusion Injury/*drug therapy
Animals ; Cytokines/metabolism ; Disease Models, Animal ; Gerbillinae ; Hippocampus/drug effects ; Male ; Nerve Tissue Proteins ; Neurons/drug effects ; Neurons/metabolism ; Neuroprotection ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Tat-Biliverdin Reductase A Exerts a Protective Role in Oxidative Stress-Induced Hippocampal Neuronal Cell Damage by Regulating the Apoptosis and MAPK Signaling.
Autorzy :
Kim SJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Yeo HJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Sohn EJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si 31538, Korea.
Eum WS; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 11; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 11.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Products, tat*/genetics
Oxidoreductases Acting on CH-CH Group Donors*/genetics
Apoptosis/*drug effects
MAP Kinase Signaling System/*drug effects
Oxidative Stress/*drug effects
Pyramidal Cells/*drug effects
Pyramidal Cells/*metabolism
Recombinant Fusion Proteins/*pharmacology
Animals ; Brain Ischemia/drug therapy ; Brain Ischemia/etiology ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Cell Line ; Disease Models, Animal ; Gerbillinae ; Hydrogen Peroxide/metabolism ; Male ; Neuroprotective Agents/pharmacology ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
MicroRNA-22 negatively regulates LPS-induced inflammatory responses by targeting HDAC6 in macrophages.
Autorzy :
Youn GS; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee CY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Jang JH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yun SH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Apr; Vol. 53 (4), pp. 223-228.
Typ publikacji :
Journal Article
MeSH Terms :
Histone Deacetylase 6/*genetics
Histone Deacetylase 6/*metabolism
MicroRNAs/*genetics
Animals ; Cytokines/metabolism ; Inflammation/genetics ; Inflammation/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Macrophages/physiology ; Mice ; MicroRNAs/metabolism ; NF-kappa B/metabolism ; RAW 264.7 Cells ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation.
Autorzy :
Choi M; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea. .
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 17; Vol. 10 (1), pp. 4887. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dermis/*metabolism
Glucose/*metabolism
Hair Follicle/*metabolism
Histones/*metabolism
Acetylation ; Animals ; Blotting, Western ; Cell Survival/physiology ; Dietary Carbohydrates/metabolism ; Female ; Glycolysis/physiology ; Meta-Analysis as Topic ; Mice, Inbred C57BL ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Nintedanib ameliorates animal model of dermatitis.
Autorzy :
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea. .
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 11; Vol. 10 (1), pp. 4493. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dermatitis/*drug therapy
Dermatitis/*metabolism
Indoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Animals ; Biomarkers ; Biopsy ; Cell Line ; Cell Survival ; Dermatitis/etiology ; Dermatitis/pathology ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Gene Expression ; Immunoglobulin E/blood ; Immunoglobulin E/immunology ; Mice ; Oxazolone/adverse effects ; Skin/drug effects ; Skin/metabolism ; Skin/pathology ; Vascular Endothelial Growth Factor Receptor-1/genetics ; Vascular Endothelial Growth Factor Receptor-1/metabolism
Czasopismo naukowe
Tytuł :
Comprehensive analyses of safety and efficacy toward individualizing imatinib dosage in patients with chronic myeloid leukemia.
Autorzy :
Shin H; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea.; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Kee KM; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Yang SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Jung SY; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea.; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Noh H; Department of Pharmacy, College of Pharmacy, Yonsei University, Incheon, South Korea.
Zang DY; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea. .; Department of Hematology, Catholic Hematology Hospital, Leukemia Research Institute, The Catholic University of Korea, 222 Banpo-Daero, Seocho-Gu, Seoul, 06591, Republic of Korea. .
Lee JI; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea. .; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Mar; Vol. 111 (3), pp. 417-426. Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article
MeSH Terms :
Precision Medicine*
Imatinib Mesylate/*administration & dosage
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Body Weight ; Female ; Humans ; Imatinib Mesylate/adverse effects ; Male ; Middle Aged ; Neutropenia/chemically induced ; Safety ; Thrombocytopenia/chemically induced ; Time Factors ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Differential roles of exogenous protein disulfide isomerase A3 on proliferating cell and neuroblast numbers in the normal and ischemic gerbils.
Autorzy :
Yoo DY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, South Korea.
Cho SB; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Nam SM; Department of Anatomy, College of Veterinary Medicine, Konkuk University, Seoul, South Korea.
Kim JW; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, South Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
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Źródło :
Brain and behavior [Brain Behav] 2020 Mar; Vol. 10 (3), pp. e01534. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*pathology
Cell Proliferation/*drug effects
Hippocampus/*drug effects
Neural Stem Cells/*drug effects
Neurogenesis/*drug effects
Protein Disulfide-Isomerases/*pharmacology
Animals ; Cell Count ; Gerbillinae ; Male ; Phosphorylation
Czasopismo naukowe
Tytuł :
Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine.
Autorzy :
Tran HQ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Saito K; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Toyoake, Japan. Electronic address: .
Tran TV; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Phan DH; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Sharma N; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chunchon, 24252, Republic of Korea.
Jeong JH; Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
Jang CG; Department of Pharmacology, School of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Cheong JH; Department of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Toyoake, Japan; Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan.
Kim HC; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2020 Feb; Vol. 136, pp. 110986. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antimanic Agents/*therapeutic use
Bipolar Disorder/*drug therapy
Indoleamine-Pyrrole 2,3,-Dioxygenase/*metabolism
Lithium/*therapeutic use
Valproic Acid/*therapeutic use
Animals ; Bipolar Disorder/chemically induced ; Bipolar Disorder/metabolism ; Calcium/metabolism ; Dextroamphetamine ; Glutathione Peroxidase/metabolism ; Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics ; Locomotion/drug effects ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/drug effects ; Mitochondria/metabolism ; Prefrontal Cortex/pathology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
PEP-1-GLRX1 protein exhibits anti-inflammatory effects by inhibiting the activation of MAPK and NF-κB pathways in Raw 264.7 cells.
Autorzy :
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252; Genesen Inc., Seoul 06181, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Feb; Vol. 53 (2), pp. 106-111.
Typ publikacji :
Journal Article
MeSH Terms :
Peptides*
Anti-Inflammatory Agents/*pharmacology
Cysteamine/*analogs & derivatives
Glutaredoxins/*pharmacology
Inflammation/*metabolism
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
NF-kappa B/*metabolism
Animals ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Edema/chemically induced ; Edema/metabolism ; Edema/therapy ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Mitogen-Activated Protein Kinases/metabolism ; Nitric Oxide Synthase Type II/antagonists & inhibitors ; Nitric Oxide Synthase Type II/metabolism ; Phosphorylation ; RAW 264.7 Cells ; Signal Transduction/drug effects ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł :
2-deoxy-d-glucose Ameliorates Animal Models of Dermatitis.
Autorzy :
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
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Źródło :
Biomedicines [Biomedicines] 2020 Jan 24; Vol. 8 (2). Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Could Defatted Mealworm ( Tenebrio molitor ) and Mealworm Oil Be Used as Food Ingredients?
Autorzy :
Son YJ; Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung Institute of Natural Products, Gangneung, Gangwon-do 25451, Korea.; Department of Food and Nutrition and Research Institute of Human Ecology, Seoul National University, Seoul 08826, Korea.
Choi SY; Sempio, Seoul 04557, Korea.
Hwang IK; Department of Food and Nutrition and Research Institute of Human Ecology, Seoul National University, Seoul 08826, Korea.
Nho CW; Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung Institute of Natural Products, Gangneung, Gangwon-do 25451, Korea.
Kim SH; Department of Culinary Arts, Kyungmin University, Uijeongbu, Gyeonggi-do 11618, Korea.
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Źródło :
Foods (Basel, Switzerland) [Foods] 2020 Jan 02; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 02.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest.
Autorzy :
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Cho JH; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Park Y; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ohk TG; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park CW; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Hong S; Department of Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2020 Jan 01; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
MicroRNA-Based Combinatorial Cancer Therapy: Effects of MicroRNAs on the Efficacy of Anti-Cancer Therapies.
Autorzy :
Seo HA; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Sim S; Generoath, Seachang-ro, Mapo-gu, Seoul 04168, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
Cells [Cells] 2019 Dec 20; Vol. 9 (1). Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antineoplastic Agents/*therapeutic use
MicroRNAs/*genetics
Neoplasms/*drug therapy
Antineoplastic Agents/pharmacology ; Drug Resistance, Neoplasm/drug effects ; Drug Synergism ; Extracellular Vesicles/drug effects ; Extracellular Vesicles/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MicroRNAs/antagonists & inhibitors ; Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Transduced Tat-CIAPIN1 reduces the inflammatory response on LPS- and TPA-induced damages.
Autorzy :
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
You JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim JS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim MY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31538, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2019 Dec; Vol. 52 (12), pp. 695-699.
Typ publikacji :
Journal Article
MeSH Terms :
Intracellular Signaling Peptides and Proteins*
Inflammation/*therapy
Animals ; Apoptosis/drug effects ; Cyclooxygenase 2/metabolism ; Disease Models, Animal ; Edema/therapy ; Inflammation/immunology ; Interleukin-6/metabolism ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred ICR ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/metabolism ; RAW 264.7 Cells ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Tetradecanoylphorbol Acetate/toxicity ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia.
Autorzy :
Han SH; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Korm S; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea.
Han YG; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Chung HJ; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Park K; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Kim JY; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea.
Myung K; Center for Genomic Integrity Institute for Basic Science (IBS), Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
Lee JY; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea.; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, Korea.
Kim H; Center for Genomic Integrity Institute for Basic Science (IBS), Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Hematology, Seoul St. Mary's Hematology Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
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Źródło :
Autophagy [Autophagy] 2019 Dec; Vol. 15 (12), pp. 2076-2090. Date of Electronic Publication: 2019 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Autophagy/*genetics
Autophagy-Related Protein-1 Homolog/*metabolism
Calcium-Binding Proteins/*metabolism
Imatinib Mesylate/*pharmacology
Intracellular Signaling Peptides and Proteins/*metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*metabolism
Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Autophagy/drug effects ; Autophagy-Related Protein-1 Homolog/chemistry ; Autophagy-Related Protein-1 Homolog/genetics ; Calcium-Binding Proteins/genetics ; Cell Survival/drug effects ; Cell Survival/genetics ; Drug Resistance, Neoplasm/drug effects ; Female ; Humans ; Intracellular Signaling Peptides and Proteins/chemistry ; Intracellular Signaling Peptides and Proteins/genetics ; K562 Cells ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukocytes, Mononuclear/metabolism ; Mice ; Mice, Inbred BALB C ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Transcriptome/genetics ; Transplantation, Heterologous ; Ubiquitination/drug effects ; Ubiquitination/genetics
Czasopismo naukowe
Tytuł :
Role of pyridoxine in GABA synthesis and degradation in the hippocampus.
Autorzy :
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, South Korea.
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Nam SM; Department of Anatomy, College of Veterinary Medicine, Konkuk University, Seoul 05030, South Korea.
Kim JW; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Yoo DY; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31151, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, South Korea. Electronic address: .
Hwang IK; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea. Electronic address: .
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Źródło :
Tissue & cell [Tissue Cell] 2019 Dec; Vol. 61, pp. 72-78. Date of Electronic Publication: 2019 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Hippocampus/*metabolism
Pyridoxine/*metabolism
gamma-Aminobutyric Acid/*biosynthesis
4-Aminobutyrate Transaminase/metabolism ; Animals ; Glutamate Decarboxylase/metabolism ; Male ; Mice, Inbred C57BL ; Succinate-Semialdehyde Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł :
Phosphatidylethanolamine-Binding Protein 1 Ameliorates Ischemia-Induced Inflammation and Neuronal Damage in the Rabbit Spinal Cord.
Autorzy :
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea. .; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. .
Cho SB; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea. .
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. .
Yoo DY; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31151, Korea. .
Oh JK; Department of Neurosurgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Pyeongchon 14068, Korea. .
Choi GM; Department of Thoracic and Cardiovascular Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon 24253, Korea. .
Cho TG; Department of Neurosurgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul 07441, Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea. .
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. .
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea. .
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong 18450, Korea. .; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon 24253, Korea. .
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Źródło :
Cells [Cells] 2019 Oct 31; Vol. 8 (11). Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons/*metabolism
Phosphatidylethanolamine Binding Protein/*metabolism
Reperfusion Injury/*pathology
Spinal Cord/*metabolism
Animals ; Apoptosis/drug effects ; Cysteamine/analogs & derivatives ; Cysteamine/metabolism ; Cytokines/metabolism ; DNA Damage/drug effects ; Down-Regulation/drug effects ; HMGB1 Protein/metabolism ; Humans ; Hydrogen Peroxide/pharmacology ; Inflammation ; Male ; Malondialdehyde/metabolism ; Mice ; Neurons/drug effects ; Oxidative Stress/drug effects ; Peptides/genetics ; Peptides/metabolism ; Phosphatidylethanolamine Binding Protein/genetics ; Rabbits ; Recombinant Fusion Proteins/administration & dosage ; Recombinant Fusion Proteins/biosynthesis ; Recombinant Fusion Proteins/pharmacology ; Reperfusion Injury/drug therapy ; Reperfusion Injury/metabolism
Czasopismo naukowe
Tytuł :
Transduced Tat-aldose Reductase Protects Hippocampal Neuronal Cells against Oxidative Stress-induced Damage.
Autorzy :
Cho SB; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kang JH; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31538, Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31538, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Experimental neurobiology [Exp Neurobiol] 2019 Oct 31; Vol. 28 (5), pp. 612-627.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A 2-Min Transient Ischemia Confers Cerebral Ischemic Tolerance in Non-Obese Gerbils, but Results in Neuronal Death in Obese Gerbils by Increasing Abnormal mTOR Activation-Mediated Oxidative Stress and Neuroinflammation.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Korea. .
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Song M; Center for Virus Research and Testing, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea. .
Kim H; Knotus Co. Ltd., Incheon 22014, Korea. .
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Park YE; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Korea. .
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam 31116, Korea. .
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. .
Yan BC; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical college of Yangzhou University, Yangzhou 225001, China. .
Ryoo S; Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
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Źródło :
Cells [Cells] 2019 Sep 22; Vol. 8 (10). Date of Electronic Publication: 2019 Sep 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hippocampus/*pathology
Ischemic Attack, Transient/*complications
Obesity/*metabolism
Obesity/*pathology
TOR Serine-Threonine Kinases/*metabolism
Animals ; Case-Control Studies ; Cell Death ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Gerbillinae ; Hippocampus/cytology ; Hippocampus/metabolism ; Interleukin-1beta/metabolism ; Ischemic Attack, Transient/metabolism ; Ischemic Attack, Transient/pathology ; Male ; Neurons/cytology ; Neurons/metabolism ; Obesity/chemically induced ; Oxidative Stress/drug effects ; Phosphorylation ; Sirolimus/pharmacology ; Tumor Necrosis Factor-alpha/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Optimal Time Points for BCR-ABL1 Tyrosine Kinase Domain Mutation Analysis on the Basis of European LeukemiaNet Recommendations in Chronic Myeloid Leukemia.
Autorzy :
Yoo HL; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Lee SE; Department of Hematology, Seoul St Mary's Hematology Hospital, The Catholic University of Korea, Seoul, South Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea; Department of Hematology, Seoul St Mary's Hematology Hospital, The Catholic University of Korea, Seoul, South Korea. Electronic address: .
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Źródło :
Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2019 Jul; Vol. 19 (7), pp. 406-412.e1. Date of Electronic Publication: 2019 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Protein Interaction Domains and Motifs*
Fusion Proteins, bcr-abl/*genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Child ; Cytogenetic Analysis ; Female ; Fusion Proteins, bcr-abl/chemistry ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Protective effects of N,4,5-trimethylthiazol-2-amine hydrochloride on hypoxia-induced β-amyloid production in SH-SY5Y cells.
Autorzy :
Han AR; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Yang JW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Na JM; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2019 Jul; Vol. 52 (7), pp. 439-444.
Typ publikacji :
Wiadomości
MeSH Terms :
Amyloid beta-Peptides/*antagonists & inhibitors
Antioxidants/*pharmacology
Cytoprotection/*drug effects
Thiazoles/*pharmacology
Amyloid Precursor Protein Secretases/antagonists & inhibitors ; Amyloid Precursor Protein Secretases/metabolism ; Amyloid beta-Peptides/biosynthesis ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Autophagy/drug effects ; Cell Hypoxia ; Cell Survival/drug effects ; Humans ; Inflammation/drug therapy ; Inflammation/metabolism ; Molecular Structure ; Oxidative Stress/drug effects ; Thiazoles/chemical synthesis ; Thiazoles/chemistry ; Tumor Cells, Cultured
Periodyk
Tytuł :
Fluoro-Jade B histofluorescence staining detects dentate granule cell death after repeated five-minute transient global cerebral ischemia.
Autorzy :
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallimdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea.
Ohk TG; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon, 25457, Republic of Korea.
Kim H; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Song M; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Yang GE; Department of Radiology, Kangwon National University Hospital, Chuncheon, Gangwon, 24289, Republic of Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallimdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea. .
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallimdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea. .
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Źródło :
Metabolic brain disease [Metab Brain Dis] 2019 Jun; Vol. 34 (3), pp. 951-956. Date of Electronic Publication: 2019 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluoresceins/*metabolism
Hippocampus/*metabolism
Ischemic Attack, Transient/*metabolism
Neurons/*metabolism
Animals ; CA1 Region, Hippocampal/metabolism ; Cell Death/physiology ; Dentate Gyrus/metabolism ; Gliosis/metabolism ; Ischemic Attack, Transient/pathology ; Male ; Pyramidal Cells/metabolism
Czasopismo naukowe
Tytuł :
Tat-CIAPIN1 inhibits hippocampal neuronal cell damage through the MAPK and apoptotic signaling pathways.
Autorzy :
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si, 31538, South Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2019 May 01; Vol. 135, pp. 68-78. Date of Electronic Publication: 2019 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*genetics
Gene Products, tat/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Neurodegenerative Diseases/*genetics
Animals ; Apoptosis/genetics ; Brain/drug effects ; Brain/metabolism ; Brain Ischemia/pathology ; Brain Ischemia/prevention & control ; Cell Survival/drug effects ; DNA Fragmentation/drug effects ; Disease Models, Animal ; Genetic Therapy ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Hydrogen Peroxide/metabolism ; Intracellular Signaling Peptides and Proteins/therapeutic use ; Mice ; Neurodegenerative Diseases/pathology ; Neurodegenerative Diseases/prevention & control ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Detection of Chilomastix mesnili in Common Marmoset ( Callithrix jacchus ) and Treatment with Metronidazole.
Autorzy :
Jeong ES; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea.
Park JH; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Ryu SH; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Choi SY; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Lee KS; Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea.
Kim JM; Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea.
Hyun BH; Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea.
Choi YK; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
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Źródło :
Iranian journal of parasitology [Iran J Parasitol] 2019 Apr-Jun; Vol. 14 (2), pp. 334-339.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Fate of Astrocytes in The Gerbil Hippocampus After Transient Global Cerebral Ischemia.
Autorzy :
Kim H; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .; Department of Anesthesiology and Pain Medicine, Chungju Hospital, Konkuk University School of Medicine, Chungju, Chungcheongbuk 27376, Korea. .
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Song M; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Park YE; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Ryoo S; Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457, Korea. .
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. .
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Feb 15; Vol. 20 (4). Date of Electronic Publication: 2019 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Lineage*
Astrocytes/*pathology
Gerbillinae/*physiology
Hippocampus/*pathology
Ischemic Attack, Transient/*pathology
Animals ; Astrocytes/metabolism ; Glial Fibrillary Acidic Protein/metabolism ; Ischemic Attack, Transient/metabolism ; Male ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils.
Autorzy :
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457, Korea. .
Kim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Song M; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim H; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .; Department of Anesthesiology and Pain Medicine, Chungju Hospital, Konkuk University School of Medicine, Chungju, Chungcheongbuk 27376, Korea. .
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea. .
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Jan 28; Vol. 20 (3). Date of Electronic Publication: 2019 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*therapeutic use
Hippocampus/*pathology
Ischemic Attack, Transient/*drug therapy
Neurons/*pathology
Obesity/*drug therapy
Polysaccharides/*therapeutic use
Aldehydes/metabolism ; Animals ; Antioxidants/pharmacology ; Cell Death/drug effects ; Diet, High-Fat ; Gerbillinae ; Ischemic Attack, Transient/metabolism ; Ischemic Attack, Transient/pathology ; Male ; Neurons/drug effects ; Neurons/metabolism ; Neuroprotection/drug effects ; Obesity/pathology ; Oxidative Stress/drug effects ; Polysaccharides/pharmacology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Compound mutations involving T315I and P-loop mutations are the major components of multiple mutations detected in tyrosine kinase inhibitor resistant chronic myeloid leukemia.
Autorzy :
Kang KH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Yoo HL; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Lee MY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Song HY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kee KM; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Suh JH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Yang SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Jang EJ; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Lee SE; Catholic Hematology Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea; Catholic Hematology Hospital, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Leukemia research [Leuk Res] 2019 Jan; Vol. 76, pp. 87-93. Date of Electronic Publication: 2018 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Drug Resistance, Neoplasm/*genetics
Fusion Proteins, bcr-abl/*genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
Protein Kinase Inhibitors/*pharmacology
Adolescent ; Adult ; Aged ; Alleles ; Antineoplastic Agents/pharmacology ; Cloning, Molecular ; Female ; Fusion Proteins, bcr-abl/chemistry ; Gene Expression ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Neuroprotective effects of Tat-ATOX1 protein against MPP -induced SH-SY5Y cell deaths and in MPTP-induced mouse model of Parkinson's disease.
Autorzy :
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Lee CH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si, 31538, South Korea.
Kwon OS; Department of Biochemistry, Kyungpook National University, Daegu, 41566, South Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2019 Jan; Vol. 156, pp. 158-168. Date of Electronic Publication: 2018 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cation Transport Proteins*/biosynthesis
Cation Transport Proteins*/genetics
Metallochaperones*/biosynthesis
Metallochaperones*/genetics
Molecular Chaperones*/biosynthesis
Molecular Chaperones*/genetics
Recombinant Fusion Proteins*/biosynthesis
Recombinant Fusion Proteins*/genetics
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/*pharmacology
MPTP Poisoning/*prevention & control
Animals ; Cell Death/drug effects ; Cell Line, Tumor ; Copper Transport Proteins ; Humans ; MPTP Poisoning/metabolism ; MPTP Poisoning/pathology ; Male ; Mice ; Transduction, Genetic
Czasopismo naukowe
Tytuł :
Protein disulfide-isomerase A3 significantly reduces ischemia-induced damage by reducing oxidative and endoplasmic reticulum stress.
Autorzy :
Yoo DY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam, 31151, South Korea.
Cho SB; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Lee KY; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Kim JW; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, 18450, South Korea; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, 24253, South Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Choi JH; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2019 Jan; Vol. 122, pp. 19-30. Date of Electronic Publication: 2018 Nov 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress/*physiology
Protein Disulfide-Isomerases/*metabolism
Reactive Oxygen Species/*metabolism
Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Hydrogen Peroxide/pharmacology ; Microglia/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways.
Autorzy :
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee SH; R&D Center, Lumieye Genetics Co., Ltd., Seoul 06198, Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan 31066, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2018 Dec; Vol. 51 (12), pp. 654-659.
Typ publikacji :
Journal Article
MeSH Terms :
Cation Transport Proteins/*metabolism
Mitogen-Activated Protein Kinases/*metabolism
Molecular Chaperones/*metabolism
NF-kappa B/*metabolism
Animals ; Cation Transport Proteins/genetics ; Copper Transport Proteins ; Cyclooxygenase 2/metabolism ; Disease Models, Animal ; Down-Regulation/drug effects ; Edema/chemically induced ; Edema/pathology ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Molecular Chaperones/genetics ; Nitric Oxide Synthase Type II/metabolism ; RAW 264.7 Cells ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Signal Transduction/drug effects ; Tetradecanoylphorbol Acetate/toxicity
Czasopismo naukowe
Tytuł :
Effects of silk solution against laminectomy-induced dural adhesion formation and inflammation in a rat model.
Autorzy :
Cho YJ; 1Department of Neurosurgery, Hallym University Medical Center, Chuncheon.
Lee CH; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Kim DW; 3Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung; and.
Yoo KY; 4Department of Oral Anatomy, College of Dentistry and Research Institute of Oral Biology, Gangneung-Wonju National University, Gangneung, Korea.
Eum WS; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Shin MJ; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Jo HS; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Park J; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Han KH; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Lee KW; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
Choi SY; 2Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon.
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Źródło :
Journal of neurosurgery. Spine [J Neurosurg Spine] 2018 Nov 01; Vol. 29 (5), pp. 599-607.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation/*complications
Laminectomy/*adverse effects
Silk/*adverse effects
Animals ; Disease Models, Animal ; Interleukin-1beta/metabolism ; Nitric Oxide/metabolism ; Rats
Czasopismo naukowe
Tytuł :
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induced cytotoxicity by regulating oxidative stress and mitochondrial dysfunction in SH-SY5Y cells.
Autorzy :
Yang SJ; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Yang JW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Na JM; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Ha JS; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chunchon 24252, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2018 Nov; Vol. 51 (11), pp. 590-595.
Typ publikacji :
Journal Article
MeSH Terms :
1-Methyl-4-phenylpyridinium/*toxicity
Azetidines/*pharmacology
Cytoprotection/*drug effects
Mitochondria/*drug effects
Naphthalenes/*pharmacology
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Apoptosis/drug effects ; Cell Line, Tumor ; Humans ; Microglia/drug effects ; Microglia/physiology ; Mitochondria/metabolism ; Neurons/physiology ; Neurotoxicity Syndromes/pathology ; Neurotoxicity Syndromes/prevention & control ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
PEP-1-PEA15 suppresses inflammatory responses by regulation of MAPK in macrophages and animal models.
Autorzy :
Yong JI; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Jo HS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Cho SB; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee CH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kim JA; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Hwang JS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si 31538, Republic of Korea.
Kim HA; Division of Rheumatology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Kyunggi 14068, Republic of Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Republic of Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea. Electronic address: .
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Źródło :
Immunobiology [Immunobiology] 2018 Nov; Vol. 223 (11), pp. 709-717. Date of Electronic Publication: 2018 Jul 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cysteamine/*analogs & derivatives
Edema/*immunology
Inflammation/*immunology
Intracellular Signaling Peptides and Proteins/*metabolism
Macrophages/*immunology
Peptides/*metabolism
Phosphoproteins/*metabolism
Animals ; Apoptosis Regulatory Proteins ; Cysteamine/metabolism ; Cytokines/metabolism ; DNA Fragmentation ; Disease Models, Animal ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Inflammation Mediators/metabolism ; Lipopolysaccharides/immunology ; Male ; Mice ; Mice, Inbred ICR ; RAW 264.7 Cells ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Tetradecanoylphorbol Acetate/immunology
Czasopismo naukowe
Tytuł :
BCR-ABL1 transcript levels at 4 weeks have prognostic significance for time-specific responses and for predicting survival in chronic-phase chronic myeloid leukemia patients treated with various tyrosine kinase inhibitors.
Autorzy :
Song HY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Noh H; Department of Pharmacy, College of Pharmacy, Yonsei University, Incheon, Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Lee SE; Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Kee KM; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Yoo HL; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Lee MY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Kang KH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Suh JH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Yang SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Jang EJ; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.
Lee JI; Department of Pharmacy, Seoul National University Hospital, Seoul, Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, Korea.; Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
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Źródło :
Cancer medicine [Cancer Med] 2018 Oct; Vol. 7 (10), pp. 5107-5117. Date of Electronic Publication: 2018 Aug 31.
Typ publikacji :
Journal Article
MeSH Terms :
Fusion Proteins, bcr-abl/*genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Protein Kinase Inhibitors/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukocyte Count ; Male ; Middle Aged ; Prognosis ; Protein Kinase Inhibitors/pharmacology ; Survival Analysis ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
PEP-1-paraoxonase 1 fusion protein prevents cytokine-induced cell destruction and impaired insulin secretion in rat insulinoma cells.
Autorzy :
Lee SJ; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Kang HK; Department of Physiology, College of Medicine, Korea University, Seoul 02841, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2018 Oct; Vol. 51 (10), pp. 538-543.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Aryldialkylphosphatase/*pharmacology
Cysteamine/*analogs & derivatives
Cytokines/*adverse effects
Insulin Secretion/*drug effects
Insulinoma/*metabolism
Insulinoma/*pathology
Peptides/*pharmacology
Recombinant Fusion Proteins/*pharmacology
Animals ; Cell Line, Tumor ; Cell Survival ; Cysteamine/pharmacology ; Endoplasmic Reticulum Stress/drug effects ; Inflammation Mediators/metabolism ; Nitric Oxide/biosynthesis ; Nitrites/metabolism ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Vaccine potential of ESAT-6 protein fused with consensus CD4 T-cell epitopes of PE/PPE proteins against highly pathogenic Mycobacterium tuberculosis strain HN878.
Autorzy :
Choi SY; Department of Microbiology, Yonsei University College of Medicine, Seoul, 03722, South Korea; Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Kwon KW; Department of Microbiology, Yonsei University College of Medicine, Seoul, 03722, South Korea; Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Kim H; Department of Microbiology, Yonsei University College of Medicine, Seoul, 03722, South Korea; Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Choi HH; Department of Microbiology, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Shin SJ; Department of Microbiology, Yonsei University College of Medicine, Seoul, 03722, South Korea; Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, 03722, South Korea. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Sep 18; Vol. 503 (4), pp. 2195-2201. Date of Electronic Publication: 2018 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Bacterial/*immunology
Bacterial Proteins/*immunology
Epitopes, T-Lymphocyte/*immunology
Mycobacterium tuberculosis/*immunology
Vaccines, Subunit/*chemical synthesis
Amino Acid Sequence ; Animals ; Antigens, Bacterial/genetics ; Antigens, Bacterial/therapeutic use ; Bacterial Proteins/genetics ; Bacterial Proteins/therapeutic use ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/therapeutic use ; Interferon-gamma/drug effects ; Interferon-gamma/metabolism ; Interleukin-2/metabolism ; Mice ; Mycobacterium tuberculosis/drug effects ; Protein Engineering ; Recombinant Fusion Proteins/immunology ; Recombinant Fusion Proteins/pharmacology ; Vaccines, Subunit/pharmacology
Czasopismo naukowe
Tytuł :
Phosphatidylethanolamine-binding protein 1 protects CA1 neurons against ischemic damage via ERK-CREB signaling in Mongolian gerbils.
Autorzy :
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Cho SB; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Yoo DY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31151, South Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Choi GM; Department of Thoracic and Cardiovascular Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon 24253, South Korea.
Cho TG; Department of Neurosurgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul 07441, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea. Electronic address: .
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong 18450, South Korea; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon 24253, South Korea. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2018 Sep; Vol. 118, pp. 265-274.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*metabolism
Brain Ischemia/*prevention & control
CA1 Region, Hippocampal/*metabolism
Cyclic AMP Response Element-Binding Protein/*metabolism
MAP Kinase Signaling System/*physiology
Phosphatidylethanolamine Binding Protein/*metabolism
Animals ; Brain Ischemia/pathology ; CA1 Region, Hippocampal/pathology ; Cell Line ; Gerbillinae ; Locomotion/physiology ; Male ; Mice ; Neurons/metabolism ; Neurons/pathology
Czasopismo naukowe
Tytuł :
Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease.
Autorzy :
Branford S; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Pharmacy and Medical Science, Division of Health Sciences, University of South Australia, Adelaide, Australia.; School of Medicine, Faculty of Health and Medical Sciences, and.; School of Biological Sciences, Faculty of Sciences, University of Adelaide, Adelaide, Australia.
Wang P; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; Australian Cancer Research Foundation Genomics Facility and.
Yeung DT; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Medicine, Faculty of Health and Medical Sciences, and.; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia.; Australasian Leukaemia and Lymphoma Group, Melbourne, Australia.
Thomson D; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Purins A; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Wadham C; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Shahrin NH; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Marum JE; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Nataren N; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Parker WT; School of Pharmacy and Medical Science, Division of Health Sciences, University of South Australia, Adelaide, Australia.; Australian Cancer Research Foundation Genomics Facility and.
Geoghegan J; Australian Cancer Research Foundation Genomics Facility and.
Feng J; Australian Cancer Research Foundation Genomics Facility and.
Shanmuganathan N; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Mueller MC; Institute for Hematology and Oncology, Mannheim, Germany.
Dietz C; Institute for Hematology and Oncology, Mannheim, Germany.
Stangl D; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Donaldson Z; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Altamura H; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Georgievski J; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Braley J; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Brown A; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Hahn C; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Walker I; Department of Haematological Medicine, King's College London, London, United Kingdom.
Kim SH; Korea Leukemia Bank.; Catholic Leukemia Research Institute, and.
Choi SY; Catholic Leukemia Research Institute, and.
Park SH; Catholic Leukemia Research Institute, and.
Kim DW; Korea Leukemia Bank.; Catholic Leukemia Research Institute, and.; Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
White DL; School of Medicine, Faculty of Health and Medical Sciences, and.; School of Biological Sciences, Faculty of Sciences, University of Adelaide, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia.; Australasian Leukaemia and Lymphoma Group, Melbourne, Australia.; Division of Health Sciences, University of South Australia, Adelaide, Australia; and.
Yong ASM; School of Medicine, Faculty of Health and Medical Sciences, and.; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia.; Australasian Leukaemia and Lymphoma Group, Melbourne, Australia.
Ross DM; School of Medicine, Faculty of Health and Medical Sciences, and.; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia.; Australasian Leukaemia and Lymphoma Group, Melbourne, Australia.; Department of Haematology, Flinders University and Medical Centre, Bedford Park, Australia.
Scott HS; Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; School of Pharmacy and Medical Science, Division of Health Sciences, University of South Australia, Adelaide, Australia.; School of Medicine, Faculty of Health and Medical Sciences, and.; School of Biological Sciences, Faculty of Sciences, University of Adelaide, Adelaide, Australia.
Schreiber AW; School of Pharmacy and Medical Science, Division of Health Sciences, University of South Australia, Adelaide, Australia.; School of Biological Sciences, Faculty of Sciences, University of Adelaide, Adelaide, Australia.; Australian Cancer Research Foundation Genomics Facility and.
Hughes TP; School of Medicine, Faculty of Health and Medical Sciences, and.; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.; South Australian Health and Medical Research Institute, Adelaide, Australia.; Australasian Leukaemia and Lymphoma Group, Melbourne, Australia.
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Źródło :
Blood [Blood] 2018 Aug 30; Vol. 132 (9), pp. 948-961. Date of Electronic Publication: 2018 Jul 02.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genomics*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/diagnosis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/mortality
Philadelphia Chromosome*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Neoplasm Proteins/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Risk Factors ; Survival Rate
Czasopismo naukowe
Tytuł :
Melatonin Improves Cognitive Deficits via Restoration of Cholinergic Dysfunction in a Mouse Model of Scopolamine-Induced Amnesia.
Autorzy :
Chen BH; Department of Histology and Embryology, Institute of Neuroscience , Wenzhou Medical University , Wenzhou , Zhejiang 325035 , P.R. China.
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology , Hallym University , Chuncheon 24252 , South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry , Kangnung-Wonju National University , Gangneung 25457 , South Korea.
Park J; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology , Hallym University , Chuncheon 24252 , South Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology , Hallym University , Chuncheon 24252 , South Korea.
Kim IH; Department of Neurobiology , School of Medicine, Kangwon National University , Chuncheon 24341 , South Korea.
Cho JH; Department of Neurobiology , School of Medicine, Kangwon National University , Chuncheon 24341 , South Korea.
Lee TK; Department of Neurobiology , School of Medicine, Kangwon National University , Chuncheon 24341 , South Korea.
Lee JC; Department of Neurobiology , School of Medicine, Kangwon National University , Chuncheon 24341 , South Korea.
Lee CH; Department of Pharmacy, College of Pharmacy , Dankook University , Cheonan 31116 , South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science , Seoul National University , Seoul 08826 , South Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine , Kangwon National University , Chuncheon , South Korea.
Yan BC; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001 , People's Republic of China.
Kang IJ; Department of Food Science and Nutrition , Hallym University , Chuncheon 24252 , South Korea.
Shin BN; Department of Physiology, College of Medicine, and Institute of Neurodegeneration and Neuroregeneration , Hallym University , Chuncheon 24252 , South Korea.
Lee YL; Department of Physiology, College of Medicine, and Institute of Neurodegeneration and Neuroregeneration , Hallym University , Chuncheon 24252 , South Korea.
Shin MC; Department of Emergency Medicine, School of Medicine , Kangwon National University , Chuncheon 24341 , South Korea.
Cho JH; Department of Emergency Medicine, School of Medicine , Kangwon National University , Chuncheon 24341 , South Korea.
Lee YJ; Department of Emergency Medicine, Seoul Hospital, College of Medicine , Sooncheonhyang University , Seoul 04401 , South Korea.
Jeon YH; Department of Radiology, School of Medicine , Kangwon National University , Chuncheon 24289 , South Korea.
Won MH; Department of Neurobiology , School of Medicine, Kangwon National University , Chuncheon 24341 , South Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology , Hallym University , Chuncheon 24252 , South Korea.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2018 Aug 15; Vol. 9 (8), pp. 2016-2024. Date of Electronic Publication: 2017 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amnesia/*drug therapy
Cognitive Dysfunction/*drug therapy
Melatonin/*pharmacology
Nootropic Agents/*pharmacology
Amnesia/metabolism ; Animals ; Choline O-Acetyltransferase/metabolism ; Cognition/drug effects ; Cognition/physiology ; Cognitive Dysfunction/metabolism ; Disease Models, Animal ; Male ; Maze Learning/drug effects ; Membrane Transport Proteins/metabolism ; Mice, Inbred ICR ; Scopolamine ; Spatial Memory/drug effects ; Vesicular Acetylcholine Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Hindsiipropane B alleviates HIV-1 Tat-induced inflammatory responses by suppressing HDAC6-NADPH oxidase-ROS axis in astrocytes.
Autorzy :
Jo H; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Jang HY; Department of Chemistry and Institute of Applied Chemistry, Hallym University, Chunchon 24252, Korea.
Youn GS; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kim D; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee CY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Jang JH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Jun JG; Department of Chemistry and Institute of Applied Chemistry, Hallym University, Chunchon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2018 Aug; Vol. 51 (8), pp. 394-399.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Histone Deacetylase 6/*antagonists & inhibitors
NADPH Oxidases/*antagonists & inhibitors
Propane/*analogs & derivatives
Propane/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
tat Gene Products, Human Immunodeficiency Virus/*metabolism
Astrocytes/metabolism ; Astrocytes/pathology ; Astrocytes/virology ; Celastrus/chemistry ; Cell Line ; Chemokines/biosynthesis ; Chemokines/immunology ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV Infections/metabolism ; HIV-1/metabolism ; Histone Deacetylase 6/metabolism ; Humans ; Inflammation/immunology ; Inflammation/virology ; MAP Kinase Signaling System/drug effects ; NADPH Oxidases/metabolism ; NF-kappa B/metabolism ; Plant Extracts/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; tat Gene Products, Human Immunodeficiency Virus/immunology
Czasopismo naukowe
Tytuł :
PEP‑1‑glutaredoxin 1 protects against hippocampal neuronal cell damage from oxidative stress via regulation of MAPK and apoptotic signaling pathways.
Autorzy :
Ryu EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of South Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Jo HS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Cho SB; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Lee CH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan‑Si, South Chungcheong 31538, Republic of South Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Republic of South Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon, Gangwon 24253, Republic of South Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Son O; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of South Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2018 Aug; Vol. 18 (2), pp. 2216-2228. Date of Electronic Publication: 2018 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteamine/*analogs & derivatives
Glutaredoxins/*pharmacology
Hippocampus/*metabolism
MAP Kinase Signaling System/*drug effects
Neurons/*metabolism
Oxidative Stress/*drug effects
Peptides/*pharmacology
Animals ; Brain Ischemia/drug therapy ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Cell Line ; Cysteamine/pharmacology ; Hippocampus/pathology ; Mice ; Neurons/pathology
Czasopismo naukowe
Tytuł :
Protective effects of Tat-DJ-1 protein against streptozotocin-induced diabetes in a mice model.
Autorzy :
Yeo H; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee CH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2018 Jul; Vol. 51 (7), pp. 362-367.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Gene Products, tat/*genetics
Protective Agents/*therapeutic use
Protein Deglycase DJ-1/*genetics
Recombinant Fusion Proteins/*therapeutic use
Alkaline Phosphatase/blood ; Animals ; Cyclooxygenase 2/metabolism ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/pathology ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Fatty Acids, Nonesterified/blood ; Insulin/blood ; Insulin-Secreting Cells/cytology ; Insulin-Secreting Cells/metabolism ; Male ; Mice ; Mice, Inbred ICR ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Oxidative Stress/drug effects ; Pancreas/metabolism ; Protective Agents/pharmacology ; Recombinant Fusion Proteins/biosynthesis ; Recombinant Fusion Proteins/pharmacology ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
Comparative analyses of nilotinib versus high-dose imatinib versus sustained standard-dose imatinib in patients with chronic phase chronic myeloid leukemia following suboptimal molecular response to first-line imatinib.
Autorzy :
Lee SE; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea; Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Jootar S; BMT Program, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kim HJ; Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea.
Sohn SK; Department of Oncology/Hematology, Kyungpook National University Hospital, Daegu, Republic of Korea.
Park JS; Department of Hematology/Oncology, Ajou University School of Medicine, Suwon, Republic of Korea.
Kim SH; Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.
Zang DY; Department of Internal Medicine, Hallym University College of Medicine, Anyang, Republic of Korea.
Oh SJ; Department of Internal Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea; Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Leukemia research [Leuk Res] 2018 Jul; Vol. 70, pp. 100-105. Date of Electronic Publication: 2018 Jun 07.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Imatinib Mesylate/*administration & dosage
Leukemia, Myeloid, Chronic-Phase/*drug therapy
Protein Kinase Inhibitors/*administration & dosage
Adolescent ; Adult ; Aged ; Biomarkers, Tumor ; Cytogenetic Analysis ; Female ; Humans ; Leukemia, Myeloid, Chronic-Phase/diagnosis ; Leukemia, Myeloid, Chronic-Phase/genetics ; Male ; Middle Aged ; Molecular Targeted Therapy ; Retreatment ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Age‑dependent decreases in insulin‑like growth factor‑I and its receptor expressions in the gerbil olfactory bulb.
Autorzy :
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Chuncheon, Gangwon 24341, Republic of Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Chuncheon, Gangwon 24341, Republic of Korea.
Lee HA; Department of Obstetrics and Gynecology, School of Medicine, Chuncheon, Gangwon 24341, Republic of Korea.
Choi JH; Department of Anatomy, College of Veterinary Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Ahn JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2018 Jun; Vol. 17 (6), pp. 8161-8166. Date of Electronic Publication: 2018 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Insulin-Like Growth Factor I/*genetics
Olfactory Bulb/*metabolism
Receptor, IGF Type 1/*genetics
Age Factors ; Animals ; Gerbillinae ; Immunohistochemistry ; Insulin-Like Growth Factor I/metabolism ; Receptor, IGF Type 1/metabolism
Czasopismo naukowe
Tytuł :
Neuronal loss and gliosis in the rat striatum subjected to 15 and 30 minutes of middle cerebral artery occlusion.
Autorzy :
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Shin BN; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Hong S; Department of Surgery, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Jeon YH; Department of Radiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Seoul, 08826, Republic of Korea.
Lee YJ; Department of Emergency Medicine, Seoul Hospital, College of Medicine, Sooncheonhyang University, 59 Daesagwan-ro, Seoul, 04401, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, Gangwon, 24341, Republic of Korea. .
Kang IJ; Department of Food Science and Nutrition, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon, 24252, Republic of Korea. .
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Źródło :
Metabolic brain disease [Metab Brain Dis] 2018 Jun; Vol. 33 (3), pp. 775-784. Date of Electronic Publication: 2018 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Death/*physiology
Corpus Striatum/*metabolism
Gliosis/*metabolism
Infarction, Middle Cerebral Artery/*pathology
Microglia/*metabolism
Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Disease Models, Animal ; Infarction, Middle Cerebral Artery/metabolism ; Ischemic Attack, Transient/metabolism ; Male ; Microglia/pathology ; Neostriatum/metabolism ; Neurons/metabolism ; Neurons/pathology ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus.
Autorzy :
Ahn JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Kim IH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Shin BN; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, South Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, Research Institute for Veterinary Science, Seoul National University, Seoul 08826, South Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, South Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.
Yan BC; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, PR China.
Lee YJ; Department of Emergency Medicine, Seoul Hospital, College of Medicine, Sooncheonhyang University, Seoul 04401, South Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea. Electronic address: .
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Źródło :
Experimental gerontology [Exp Gerontol] 2018 Mar; Vol. 103, pp. 124-131. Date of Electronic Publication: 2018 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Physical Conditioning, Animal*
Cell Adhesion Molecules/*metabolism
Hippocampus/*physiopathology
Ischemic Attack, Transient/*therapy
Memory Disorders/*therapy
Animals ; Fluorescent Antibody Technique ; Gerbillinae ; Hippocampus/blood supply ; Hippocampus/metabolism ; Immunohistochemistry ; Ischemic Attack, Transient/pathology ; Male ; Motor Activity ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Effects of Scopolamine and Melatonin Cotreatment on Cognition, Neuronal Damage, and Neurogenesis in the Mouse Dentate Gyrus.
Autorzy :
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, People's Republic of China.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Lee YL; Department of Physiology, College of Medicine, and Institute of Neurodegeneration and Neuroregeneration, Hallym University, Chuncheon, 24252, South Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, 24252, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Shin BN; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Hong S; Department of Surgery, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Jeon YH; Department of Radiology, School of Medicine, Kangwon National University, Kangwon National University Hospital, Chuncheon, 24341, South Korea.
Shin MC; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Cho JH; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, 24341, South Korea. .
Lee YJ; Department of Emergency Medicine, Seoul Hospital, College of Medicine, Sooncheonhyang University, Seoul, 04401, South Korea. .
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Źródło :
Neurochemical research [Neurochem Res] 2018 Mar; Vol. 43 (3), pp. 600-608. Date of Electronic Publication: 2017 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cognition/*drug effects
Dentate Gyrus/*drug effects
Melatonin/*pharmacology
Neurogenesis/*drug effects
Scopolamine/*pharmacology
Animals ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cognitive Dysfunction/drug therapy ; Dentate Gyrus/cytology ; Male ; Memory/drug effects ; Mice ; Neurogenesis/physiology ; Neurons/drug effects
Czasopismo naukowe
Tytuł :
Baseline BCR-ABL1 transcript type of e13a2 and large spleen size are predictors of poor long-term outcomes in chronic phase chronic myeloid leukemia patients who failed to achieve an early molecular response after 3 months of imatinib therapy.
Autorzy :
Lee SE; a Department of Hematology , Seoul St. Mary's Hospital, The Catholic University of Korea , Seoul , Korea.
Choi SY; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Kim SH; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Song HY; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Yoo HL; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Lee MY; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Hwang HJ; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Kang KH; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Kee KM; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Jang EJ; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
Kim DW; a Department of Hematology , Seoul St. Mary's Hospital, The Catholic University of Korea , Seoul , Korea.; b Leukemia Research Institute, The Catholic University of Korea , Seoul , Korea.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2018 Jan; Vol. 59 (1), pp. 105-113. Date of Electronic Publication: 2017 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Splenomegaly*
Transcription, Genetic*
Fusion Proteins, bcr-abl/*genetics
Leukemia, Myeloid, Chronic-Phase/*genetics
Leukemia, Myeloid, Chronic-Phase/*pathology
Adolescent ; Adult ; Aged ; Antineoplastic Agents/therapeutic use ; Female ; Humans ; Imatinib Mesylate/therapeutic use ; Leukemia, Myeloid, Chronic-Phase/drug therapy ; Leukemia, Myeloid, Chronic-Phase/mortality ; Male ; Middle Aged ; Prognosis ; Protein Kinase Inhibitors/therapeutic use ; Time Factors ; Treatment Failure ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Effects of chronic scopolamine treatment on cognitive impairment and neurofilament expression in the mouse hippocampus.
Autorzy :
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Park JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Ahn JH; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park J; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kim IH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Shin BN; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Kim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Song M; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Cho GS; Pharmacology and Toxicology Department, Shinpoong Pharmaceutical Co., Ltd., Ansan, Gyeonggi 15610, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, College of Dentistry, Kangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2018 Jan; Vol. 17 (1), pp. 1625-1632. Date of Electronic Publication: 2017 Nov 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cognitive Dysfunction/*drug therapy
Hippocampus/*drug effects
Intermediate Filaments/*pathology
Muscarinic Antagonists/*therapeutic use
Neurofilament Proteins/*analysis
Scopolamine/*therapeutic use
Animals ; Cognitive Dysfunction/pathology ; Hippocampus/pathology ; Male ; Mice ; Mice, Inbred ICR
Czasopismo naukowe
Tytuł :
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis.
Autorzy :
Matte A; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
De Falco L; 2 CEINGE and Department of Biochemistry, Federico II University , Naples, Italy .
Federti E; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
Cozzi A; 3 Division of Neuroscience, San Raffaele Scientific Institute , Milano, Italy .
Iolascon A; 2 CEINGE and Department of Biochemistry, Federico II University , Naples, Italy .
Levi S; 3 Division of Neuroscience, San Raffaele Scientific Institute , Milano, Italy .; 4 Vita-Salute San Raffaele University , Milano, Italy .
Mohandas N; 5 New York Blood Center , New York, New York.
Zamo A; 6 Department of Pathology and Diagnostic University of Verona-AOUI Verona , Verona, Italy .
Bruno M; 2 CEINGE and Department of Biochemistry, Federico II University , Naples, Italy .
Lebouef C; 7 Inserm, U1165, Paris, France .
Janin A; 7 Inserm, U1165, Paris, France .; 8 Université Paris 7-Denis Diderot , Paris, France .; 9 AP-HP , Hôpital Saint-Louis, Paris, France .
Siciliano A; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
Ganz T; 10 Department of Pathology and Laboratory of Medicine, UCLA School of Medicine , Los Angeles, California.
Federico G; 11 Department of Molecular Medicine and Medical Biotechnologies Federico II University , Naples, Italy .
Carlomagno F; 11 Department of Molecular Medicine and Medical Biotechnologies Federico II University , Naples, Italy .
Mueller S; 12 Medical Department, Salem Medical Center, University of Heidelberg , Heidelberg, Germany .
Silva I; 12 Medical Department, Salem Medical Center, University of Heidelberg , Heidelberg, Germany .
Carbone C; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
Melisi D; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
Kim DW; 13 Department of Biomedical Sciences, Institute of Bioscience and Biotechnology, Hallym University , Chunchon, Korea.
Choi SY; 13 Department of Biomedical Sciences, Institute of Bioscience and Biotechnology, Hallym University , Chunchon, Korea.
De Franceschi L; 1 Department of Medicine, University of Verona-AOUI Verona , Verona, Italy .
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Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2018 Jan 01; Vol. 28 (1), pp. 1-14. Date of Electronic Publication: 2017 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Erythropoiesis*
Homeostasis*
Iron/*metabolism
Peroxiredoxins/*genetics
Peroxiredoxins/*metabolism
Anemia/drug therapy ; Anemia/etiology ; Anemia/metabolism ; Animals ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Cytoprotection/genetics ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Hepcidins/genetics ; Hepcidins/metabolism ; Iron Overload/etiology ; Iron Overload/metabolism ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Knockout ; Models, Biological ; Oxidative Stress ; Peroxiredoxins/pharmacology ; Recombinant Proteins ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Effects of long‑term scopolamine treatment on cognitive deficits and calcium binding proteins immunoreactivities in the mouse hippocampus.
Autorzy :
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Yan BC; Department of Traditional Chinese and Western Medicine, Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, Jiangsu 225001, P.R. China.
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Shin BN; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Jeon YH; Department of Radiology, School of Medicine, Kangwon National University, Kangwon National University Hospital, Chuncheon 24341, Republic of Korea.
Hong S; Department of Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Lee YJ; Department of Emergency Medicine, Seoul Hospital, College of Medicine, Sooncheonhyang University, Seoul 04401, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2018 Jan; Vol. 17 (1), pp. 293-299. Date of Electronic Publication: 2017 Oct 27.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium-Binding Proteins/*metabolism
Cognitive Dysfunction/*metabolism
Hippocampus/*drug effects
Hippocampus/*metabolism
Scopolamine/*pharmacology
Animals ; Cognitive Dysfunction/drug therapy ; Immunohistochemistry ; Male ; Mice ; Spatial Memory/drug effects
Czasopismo naukowe
Tytuł :
Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia.
Autorzy :
Park JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Park CW; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, South Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Lee TK; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Kim IH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Cho JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Kim YH; Department of Surgery, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, South Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, 54596, South Korea.
Shin BN; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, South Korea.
Bae EJ; Department of Pediatrics, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon 24253, South Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, South Korea. Electronic address: .
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, South Korea. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2017 Dec 25; Vol. 278, pp. 230-238. Date of Electronic Publication: 2017 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*prevention & control
Gliosis/*prevention & control
Hydroquinones/*therapeutic use
Neuroprotective Agents/*therapeutic use
Animals ; Antigens, Nuclear/metabolism ; Astrocytes/drug effects ; Astrocytes/pathology ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Disease Models, Animal ; Gerbillinae ; Hippocampus/pathology ; Hydroquinones/pharmacology ; Immunohistochemistry ; Male ; Microglia/drug effects ; Microglia/pathology ; Motor Activity/drug effects ; Neuroprotective Agents/pharmacology
Czasopismo naukowe

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