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Tytuł :
Utilization of an Intracellular Calcium Mobilization Assay for the Screening of Transduced FK506-Binding Proteins.
Autorzy :
Cha HJ; R&D Center, Lumieye Genetics Co., Ltd., Seoul, Korea.
Lee H; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.
Park SJ; R&D Center, Lumieye Genetics Co., Ltd., Seoul, Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Korea.
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Źródło :
Assay and drug development technologies [Assay Drug Dev Technol] 2021 Oct; Vol. 19 (7), pp. 442-452. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Anti-Cancer Activity of Phytochemicals Targeting Hypoxia-Inducible Factor-1 Alpha.
Autorzy :
Yun BD; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Oh TJ; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si 31460, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 10; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Populus tomentiglandulosa Extract Is Rich in Polyphenols and Protects Neurons, Astrocytes, and the Blood-Brain Barrier in Gerbil Striatum Following Ischemia-Reperfusion Injury.
Autorzy :
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongsangnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, North Gyeongsang, Korea.
Kim HI; Department of Emergency Medicine, Dankook University Hospital, College of Medicine, Dankook University, Cheonan 31116, Chungnam, Korea.; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 07; Vol. 26 (18). Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Tat-CIAPIN1 protein prevents against cytokine-induced cytotoxicity in pancreatic RINm5F β-cells.
Autorzy :
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2021 Sep; Vol. 54 (9), pp. 458-463.
Typ publikacji :
Wiadomości
Periodyk
Tytuł :
Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia.
Autorzy :
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan, Gyeongnam 50510, Republic of Korea.
Chen BH; Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Extracts from the Leaves of Cissus verticillata Ameliorate High-Fat Diet-Induced Memory Deficits in Mice.
Autorzy :
Kim W; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy, College of Veterinary Medicine, Veterinary Science Research Institute, Konkuk University, Seoul 05030, Korea.
Kwon HJ; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Lim SS; Department of Food Science and Nutrition, Institute of Korean Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang BG; Department of Biochemistry, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Jo YB; Department of Convergence Technology, Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Yu DS; Department of Venture Management Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
Plants (Basel, Switzerland) [Plants (Basel)] 2021 Aug 31; Vol. 10 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Transduced Tat-PRAS40 prevents dopaminergic neuronal cell death through ROS inhibition and interaction with 14-3-3σ protein.
Autorzy :
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Kangneung-Wonju National University, Kangneung, 25457, South Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, 31538, South Korea.
Yu YH; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, 31538, South Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, 05505, South Korea.
Kwon OS; School of Life Sciences, College of Natural Sciences Kyungpook National University, Taegu, 41566, South Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon, 24253, South Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Aug 20; Vol. 172, pp. 418-429. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dopaminergic Neurons*
Oxidative Stress*
Animals ; Apoptosis ; Cell Death ; Mice ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cells.
Autorzy :
Kim EA
Hwang K
Kim JE
Ahn JY
Choi SY
Yang SJ
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2021 Aug 06. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Wiadomości
Periodyk
Tytuł :
Tat-thioredoxin 1 reduces inflammation by inhibiting pro-inflammatory cytokines and modulating MAPK signaling.
Autorzy :
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.; Genesen Inc., Seoul 06181, Republic of Korea.
Lee S; Department of Green Chemical Engineering, Sangmyung University, Cheonan, Chungcheongnam 31066, Republic of Korea.
Yu YH; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan, Chungcheongnam 31538, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
Experimental and therapeutic medicine [Exp Ther Med] 2021 Dec; Vol. 22 (6), pp. 1395. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Tat-p27 Ameliorates Neuronal Damage Reducing α-Synuclein and Inflammatory Responses in Motor Neurons After Spinal Cord Ischemia.
Autorzy :
Kim W; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Anatomy, College of Veterinary Medicine, and Veterinary Science Research Institute, Konkuk University, Seoul, 05030, South Korea.
Kwon HJ; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, 34134, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, 18450, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, 24253, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Choi SY; Department of Biomedical Sciences, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. .
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Źródło :
Neurochemical research [Neurochem Res] 2021 Dec; Vol. 46 (12), pp. 3123-3134. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Comparison of Neuronal Death, Blood-Brain Barrier Leakage and Inflammatory Cytokine Expression in the Hippocampal CA1 Region Following Mild and Severe Transient Forebrain Ischemia in Gerbils.
Autorzy :
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan, Chungnam, 31116, Republic of Korea.
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan, Gyeongnam, 50510, Republic of Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee TK; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon, 24252, Republic of Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk, 38066, Republic of Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Gangwon, 24289, Republic of Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Chuncheon, Gangwon, 24289, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon, 25457, Republic of Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. .
Choi SY; Department of Biomedical Science, Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon, 24252, Republic of Korea. .
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Źródło :
Neurochemical research [Neurochem Res] 2021 Nov; Vol. 46 (11), pp. 2852-2866. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Neuroprotective and Anti-Inflammatory Effects of Pinus densiflora Bark Extract in Gerbil Hippocampus Following Transient Forebrain Ischemia.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han X; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 29; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Brain Ischemia/*drug therapy
Hippocampus/*drug effects
Neuroprotective Agents/*pharmacology
Pinus/*chemistry
Prosencephalon/*drug effects
Animals ; Anti-Inflammatory Agents/chemistry ; Brain Ischemia/genetics ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Gene Expression/drug effects ; Gerbillinae ; Hippocampus/metabolism ; Hippocampus/pathology ; Inflammation ; Interleukin-13/agonists ; Interleukin-13/genetics ; Interleukin-13/metabolism ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-4/agonists ; Interleukin-4/genetics ; Interleukin-4/metabolism ; Male ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Neuroprotective Agents/chemistry ; Plant Bark/chemistry ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Proanthocyanidins/chemistry ; Proanthocyanidins/pharmacology ; Prosencephalon/metabolism ; Prosencephalon/pathology ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Changes in Cyclin D1, cdk4, and Their Associated Molecules in Ischemic Pyramidal Neurons in Gerbil Hippocampus after Transient Ischemia and Neuroprotective Effects of Ischemic Preconditioning by Keeping the Molecules in the Ischemic Neurons.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology and Research Institute of Oral Sciences, College of Dentistry, Kangnung-Wonju National University, Gangneung 25457, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Shin MC; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Cho JH; Department of Emergency Medicine, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon 24289, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Biology [Biology (Basel)] 2021 Jul 28; Vol. 10 (8). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Hypoxia-Long Noncoding RNA Interaction in Solid Cancers.
Autorzy :
Son SW; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Yun BD; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Song MG; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JK; Department of Biomedical Science, Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 06; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hypoxia/*genetics
Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Tumor Microenvironment/*genetics
Animals ; Apoptosis/genetics ; Humans ; MicroRNAs/genetics
Czasopismo naukowe
Tytuł :
Cissus verticillata Extract Decreases Neuronal Damage Induced by Oxidative Stress in HT22 Cells and Ischemia in Gerbils by Reducing the Inflammation and Phosphorylation of MAPKs.
Autorzy :
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy, College of Veterinary Medicine, Veterinary Science Research Institute, Konkuk University, Seoul 05030, Korea.
Kwon HJ; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Veterinary Medicine, Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Lim SS; Department of Food Science and Nutrition, Institute of Korean Nutrition, Hallym University, Chuncheon 24252, Korea.
Kang BG; Department of Biochemistry, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Jo YB; Department of Convergence Technology, Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Yu DS; Department of Venture Management Graduate School of Venture, Hoseo University, Seoul 06724, Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
Plants (Basel, Switzerland) [Plants (Basel)] 2021 Jun 15; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson's Disease.
Autorzy :
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee LR; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Song Y; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Kim DS; Department of Anatomy and BK21 FOUR Project, College of Medicine, Soonchunhyang University, Cheonan-si 31538, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 01; Vol. 26 (11). Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteamine/*analogs & derivatives
Dopaminergic Neurons/*cytology
Glutaredoxins/*administration & dosage
MAP Kinase Signaling System/*drug effects
Parkinson Disease/*drug therapy
Peptides/*chemistry
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/adverse effects ; 1-Methyl-4-phenylpyridinium/adverse effects ; Animals ; Apoptosis/drug effects ; Cell Line ; Cysteamine/chemistry ; Disease Models, Animal ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Gene Expression Regulation/drug effects ; Glutaredoxins/chemistry ; Glutaredoxins/pharmacology ; Humans ; Male ; Mice ; Parkinson Disease/etiology ; Parkinson Disease/metabolism ; Substantia Nigra/chemistry
Czasopismo naukowe
Tytuł :
Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway.
Autorzy :
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Republic of Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan 31538, Republic of Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.
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Źródło :
Biomolecules & therapeutics [Biomol Ther (Seoul)] 2021 May 01; Vol. 29 (3), pp. 321-330.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Comparison Between Manual and Automated Analyses in Multichannel Intraluminal Impedance: pH Monitoring for Laryngopharyngeal Reflux.
Autorzy :
Kang HJ; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Park JM; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Choi SY; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Kim SI; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Lee YC; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Eun YG; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Ko SG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.
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Źródło :
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2021 Apr 20, pp. 1945998211006929. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Neuroprotective Effects of Salicin in a Gerbil Model of Transient Forebrain Ischemia by Attenuating Oxidative Stress and Activating PI3K/Akt/GSK3β Pathway.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Lee TK; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Chungnam, Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Choi SY; Department of Biomedical Science, Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Apr 20; Vol. 10 (4). Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ischemia-Reperfusion under Hyperthermia Increases Heme Oxygenase-1 in Pyramidal Neurons and Astrocytes with Accelerating Neuronal Loss in Gerbil Hippocampus.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Gangwon, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Gyeongnam, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Gyeongbuk, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Chungnam, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Gangwon, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Gangwon, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 12; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries/*genetics
Heme Oxygenase-1/*genetics
Hippocampus/*metabolism
Reperfusion Injury/*genetics
Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Brain Injuries/metabolism ; Brain Injuries/pathology ; Gerbillinae/genetics ; Gerbillinae/metabolism ; Hippocampus/injuries ; Hippocampus/physiopathology ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Therapeutic Effects of Decursin and Angelica gigas Nakai Root Extract in Gerbil Brain after Transient Ischemia via Protecting BBB Leakage and Astrocyte Endfeet Damage.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Ahn JH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Kim JD; Division of Food Biotechnology, School of Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Angelica/*chemistry
Astrocytes/*pathology
Benzopyrans/*therapeutic use
Blood-Brain Barrier/*pathology
Butyrates/*therapeutic use
Ischemic Attack, Transient/*pathology
Plant Extracts/*therapeutic use
Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Benzopyrans/chemistry ; Benzopyrans/pharmacology ; Blood-Brain Barrier/drug effects ; Butyrates/chemistry ; Butyrates/pharmacology ; Gerbillinae ; Glial Fibrillary Acidic Protein/metabolism ; Glucose Transporter Type 1/metabolism ; Immunoglobulin G/metabolism ; Male ; Neuraminidase/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Plant Extracts/pharmacology ; Reference Standards ; Spatial Memory/drug effects
Czasopismo naukowe
Tytuł :
Modified transoral endoscopic thyroidectomy technique using trapdoor suspension sutures.
Autorzy :
Kim SI; Department of Biomedical science and technology, Graduate School, Kyung Hee University, Seoul, Korea.; Department of Otorhinolaryngology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.
Min HK; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Kang DW; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Choi SY; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Kang HJ; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Lee YC; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Eun YG; Department of Biomedical science and technology, Graduate School, Kyung Hee University, Seoul, Korea.; Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University Medical Center, Seoul, Korea.
Ko SG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea.
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Źródło :
Clinical and experimental otorhinolaryngology [Clin Exp Otorhinolaryngol] 2021 Mar 30. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
BDNF and Netrin-1 repression by C/EBPβ in the gut triggers Parkinson's disease pathologies, associated with constipation and motor dysfunctions.
Autorzy :
Ahn EH; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Kang SS; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Liu X; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.
Cao X; Department of Neurology, Union Hospital, Huazhong University of Science & Technology, Wuhan, China.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Musazzi L; Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy.
Mehlen P; Apoptosis, Cancer and Development Laboratory, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR 5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
Ye K; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA. Electronic address: .
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Źródło :
Progress in neurobiology [Prog Neurobiol] 2021 Mar; Vol. 198, pp. 101905. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Tat‑aldose reductase prevents dopaminergic neuronal cell death by inhibiting oxidative stress and MAPK activation.
Autorzy :
Cho SB; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan‑si, Chungcheong 31538, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung‑Wonju National University, Gangneung, Gangwon 25457, Republic of Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Republic of Korea.
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Źródło :
International journal of molecular medicine [Int J Mol Med] 2021 Feb; Vol. 47 (2), pp. 751-760. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
MAP Kinase Signaling System*
Oxidative Stress*
Aldehyde Reductase/*metabolism
Dopaminergic Neurons/*enzymology
Extracellular Signal-Regulated MAP Kinases/*metabolism
Substantia Nigra/*enzymology
Aldehyde Reductase/genetics ; Animals ; Cell Death ; Cell Line, Tumor ; Enzyme Activation ; Extracellular Signal-Regulated MAP Kinases/genetics ; Humans ; MPTP Poisoning/enzymology ; MPTP Poisoning/genetics ; Male ; Mice
Czasopismo naukowe
Tytuł :
Cerebral Coenurosis of a Long-Tailed Goral, Naemorhedus caudatus, in Korea.
Autorzy :
Ahn S; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Oh H; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Choi SY; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Kim JT; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
Kim HC; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
The Korean journal of parasitology [Korean J Parasitol] 2021 Feb; Vol. 59 (1), pp. 55-59. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Animals, Wild*
Artiodactyla*
Animal Diseases/*parasitology
Cysticercosis/*parasitology
Cysticercosis/*veterinary
Neglected Diseases/*parasitology
Neglected Diseases/*veterinary
Neurocysticercosis/*parasitology
Neurocysticercosis/*veterinary
Taenia/*isolation & purification
Taeniasis/*parasitology
Taeniasis/*veterinary
Animal Diseases/diagnostic imaging ; Animals ; Cerebrum/diagnostic imaging ; Cerebrum/parasitology ; Cysticercosis/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Neglected Diseases/diagnostic imaging ; Neurocysticercosis/diagnostic imaging ; Republic of Korea ; Taeniasis/diagnostic imaging ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Tyrosine Phosphorylation Modulates Peroxiredoxin-2 Activity in Normal and Diseased Red Cells.
Autorzy :
Mattè A; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Federti E; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Tibaldi E; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
Di Paolo ML; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
Bisello G; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biological Chemistry, University of Verona, 37134 Verona, Italy.
Bertoldi M; Department of Neuroscience, Biomedicine and Movement Sciences, Section of Biological Chemistry, University of Verona, 37134 Verona, Italy.
Carpentieri A; Department of Chemical Sciences, University Federico II of Napoli, 80126 Napoli, Italy.
Pucci P; Department of Chemical Sciences, University Federico II of Napoli, 80126 Napoli, Italy.; CEINGE Biotecnologie Avanzate, 80145 Napoli, Italy.
Iatchencko I; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Wilson AB; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Riccardi V; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Siciliano A; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
Turrini F; Department of Oncology, University of Torino, 10124 Torino, Italy.
Kim DW; Department of Biomedical Sciences and Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Sciences and Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Brunati AM; Department of Molecular Medicine, University of Padua, 35128 Padua, Italy.
De Franceschi L; Department of Medicine, University of Verona and AOUI Verona, 37134 Verona, Italy.
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Źródło :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Feb 01; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The Role of Noncoding RNAs in the Regulation of Anoikis and Anchorage-Independent Growth in Cancer.
Autorzy :
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 10; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anoikis*
Neoplasms/*genetics
RNA, Untranslated/*metabolism
Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/metabolism ; Neoplasms/physiopathology
Czasopismo naukowe
Tytuł :
Gynura procumbens Root Extract Ameliorates Ischemia-Induced Neuronal Damage in the Hippocampal CA1 Region by Reducing Neuroinflammation.
Autorzy :
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Yoo DY; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan 31151, Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
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Źródło :
Nutrients [Nutrients] 2021 Jan 08; Vol. 13 (1). Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
CA1 Region, Hippocampal/*drug effects
Inflammation/*drug therapy
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Plant Extracts/*pharmacology
Plant Roots/*chemistry
Animals ; Body Weight ; Brain Ischemia/pathology ; Brain Ischemia/surgery ; CA1 Region, Hippocampal/pathology ; Cytokines ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Gerbillinae ; Hippocampus/drug effects ; Male ; Microglia ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Neuronal Death in the CNS Autonomic Control Center Comes Very Early after Cardiac Arrest and Is Not Significantly Attenuated by Prompt Hypothermic Treatment in Rats.
Autorzy :
Ahn JH; Department of Physical Therapy, College of Health Science, Youngsan University, Yangsan 50510, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Tae HJ; Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Sim H; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung 25457, Korea.
Kim YS; Department of Emergency Medicine, Samcheok Medical Center, Samcheok 25920, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park Y; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju 38066, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dankook University, Cheonan 31116, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon 24341, Korea.
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Źródło :
Cells [Cells] 2021 Jan 02; Vol. 10 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypothermia, Induced*
Autonomic Nervous System/*pathology
Central Nervous System/*pathology
Heart Arrest/*pathology
Neurons/*pathology
Animals ; Antigens, Nuclear/metabolism ; Cell Death ; Male ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; Rats, Sprague-Dawley ; Survival Analysis ; Time Factors
Czasopismo naukowe
Tytuł :
AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.
Autorzy :
Sari IN; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Yang YG; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.; Shenzhen Key Laboratory of Viral Oncology, The Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Wijaya YT; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Jun N; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Lee S; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Kim KS; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Bajaj J; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
Oehler VG; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Kim SH; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Choi SY; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Park SH; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.
Kim DW; Catholic Leukemia Research Institute, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Reya T; Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Han J; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea.
Kwon HY; Soonchunhyang Institute of Medi-bio Science, Soonchunhyang University, Cheonan, Republic of Korea. .
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Źródło :
Oncogene [Oncogene] 2021 Jan; Vol. 40 (3), pp. 603-617. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Adenosylmethionine Decarboxylase/*metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*enzymology
Neoplasm Proteins/*metabolism
Neoplastic Stem Cells/*enzymology
Adenosylmethionine Decarboxylase/genetics ; Animals ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Mice ; Neoplasm Proteins/genetics ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus.
Autorzy :
Kim W; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 14; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclin-Dependent Kinase Inhibitor p27/*metabolism
Hippocampus/*drug effects
Hippocampus/*metabolism
Animals ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Gerbillinae ; Humans ; Hydrogen Peroxide/pharmacology ; Microtubule-Associated Proteins/metabolism ; Oxidative Stress/drug effects ; Phospholipids/metabolism ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/pharmacology
Czasopismo naukowe
Tytuł :
Tat-indoleamine 2,3-dioxygenase 1 elicits neuroprotective effects on ischemic injury.
Autorzy :
Park JH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Sohn EJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim HC; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon 24341, Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon 24341, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim DS; Department of Anatomy and BK21 Plus Center, College of Medicine, Soonchunhyang University, Cheonan 31538, Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Nov; Vol. 53 (11), pp. 582-587.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*physiopathology
Indoleamine-Pyrrole 2,3,-Dioxygenase/*pharmacology
Reperfusion Injury/*therapy
Animals ; Apoptosis/drug effects ; Cell Death/drug effects ; Cell Survival/drug effects ; Gerbillinae ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Ischemia/metabolism ; Male ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Reperfusion Injury/metabolism
Czasopismo naukowe
Tytuł :
N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons.
Autorzy :
Yang SJ; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Han AR; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi HR; Department of Biomedical Laboratory Science, Konyang University, Daejeon 35365, Korea.
Hwang K; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim EA; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chunchon 24252, Korea.
Cho SW; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul 05505, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Nov; Vol. 53 (10), pp. 527-532.
Typ publikacji :
Wiadomości
MeSH Terms :
Adamantane/*analogs & derivatives
Autophagy/*drug effects
Neurons/*metabolism
Thiazoles/*pharmacology
Adamantane/metabolism ; Adamantane/pharmacology ; Animals ; Antioxidants/pharmacology ; Autophagic Cell Death ; Autophagy/physiology ; Cerebral Cortex/metabolism ; Glutamic Acid/adverse effects ; Glutamic Acid/metabolism ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Neurons/drug effects ; Oxidative Stress/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Superoxide Dismutase/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Thiazoles/metabolism
Periodyk
Tytuł :
Participation of MicroRNAs in the Treatment of Cancer with Phytochemicals.
Autorzy :
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 14; Vol. 25 (20). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Gene Expression Regulation, Neoplastic/*drug effects
MicroRNAs/*genetics
Phytochemicals/*pharmacology
Animals ; Anticarcinogenic Agents/pharmacology ; Clinical Trials as Topic ; Genes, Tumor Suppressor/drug effects ; Humans ; Neoplasms/drug therapy ; Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Metformin ameliorates animal models of dermatitis.
Autorzy :
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Department of Cosmetics Engineering, Research Institute for Molecular-Targeted Drugs, Konkuk University, Seoul, 05029, South Korea.
An S; Department of Cosmetics Engineering, Research Institute for Molecular-Targeted Drugs, Konkuk University, Seoul, 05029, South Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Inflammopharmacology [Inflammopharmacology] 2020 Oct; Vol. 28 (5), pp. 1293-1300. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*drug effects
Dermatitis/*drug therapy
Enzyme Activators/*pharmacology
Metformin/*pharmacology
AMP-Activated Protein Kinases/metabolism ; Animals ; Collagen/metabolism ; Dermatitis/pathology ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Humans ; Male ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Skin/drug effects ; Skin/pathology ; Tetradecanoylphorbol Acetate
Czasopismo naukowe
Tytuł :
Fyn specifically Regulates the activity of red cell glucose-6-phosphate-dehydrogenase.
Autorzy :
Mattè A; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Lupo F; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Tibaldi E; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Di Paolo ML; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Federti E; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Carpentieri A; Dept of Chemical Sciences, University Federico II, Naples, Italy.
Pucci P; Dept of Chemical Sciences, University Federico II, Naples, Italy.
Brunati AM; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Cesaro L; Dept of Molecular Medicine, University of Padua, Padua, Italy.
Turrini F; Dept of Oncology, University of Torino, Torino, Italy.
Gomez Manzo S; Laboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City, Mexico.
Choi SY; Institute of Bioscience and Biotechnology, Hallym University, Gangowo-do, South Korea.
Marcial Quino J; Consejo Nacional de Ciencia y Tecnology, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City, Mexico.
Kim DW; Institute of Bioscience and Biotechnology, Hallym University, Gangowo-do, South Korea.
Pantaleo A; Dept of Physiology, University of Sassari, Sassari, Italy.
Xiuli A; School of Life Sciences, Zhengzhou University, Zhengzhou, China; Laboratory of Membrane Biology, New York Blood Center, New York, NY, USA.
Iatcenko I; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy.
Cappellini MD; Dept of Medicine, University of Milan, Milan, Italy.
Forni GL; Centro Della Microcitemia e Delle Anemie Congenite, Ospedale Galliera, Genova, Italy.
De Franceschi L; Dept of Medicine University of Verona and AOUI Verona, Verona, Italy. Electronic address: .
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Źródło :
Redox biology [Redox Biol] 2020 Sep; Vol. 36, pp. 101639. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucosephosphate Dehydrogenase*
Glucosephosphate Dehydrogenase Deficiency*/genetics
Animals ; Erythrocytes ; Glucose-6-Phosphate ; Hemolysis ; Mice ; Proto-Oncogene Proteins c-fyn
Czasopismo naukowe
Tytuł :
Experimental Pretreatment with Chlorogenic Acid Prevents Transient Ischemia-Induced Cognitive Decline and Neuronal Damage in the Hippocampus through Anti-Oxidative and Anti-Inflammatory Effects.
Autorzy :
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Kang IJ; Department of Food Science and Nutrition, Hallym University, Chuncheon, Gsangwon 24252, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Sim HJ; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457 Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Ryoo S; Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Shin MC; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Cho JH; Department of Emergency Medicine, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim YM; Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Park JH; Department of Anatomy, College of Oriental Medicine, Dongguk University-Gyeongju, Gyeongju, Gyeongbuk, 38066, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Aug 06; Vol. 25 (16). Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorogenic Acid/*pharmacology
Cognition/*drug effects
Hippocampus/*pathology
Ischemia/*pathology
Ischemia/*physiopathology
Neurons/*drug effects
Neurons/*pathology
Aldehydes/metabolism ; Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Hippocampus/drug effects ; Interleukin-2/metabolism ; Interleukin-4/metabolism ; Ischemia/metabolism ; Mice ; Neuroprotective Agents/pharmacology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Extracellular Vesicles (EVs) and Pancreatic Cancer: From the Role of EVs to the Interference with EV-Mediated Reciprocal Communication.
Autorzy :
Moeng S; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Son SW; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee JS; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Lee HY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kim TH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
Kuh HJ; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chunchon 24252, Korea.
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Źródło :
Biomedicines [Biomedicines] 2020 Aug 03; Vol. 8 (8). Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis.
Autorzy :
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul 05836, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 03; Vol. 21 (9). Date of Electronic Publication: 2020 May 03.
Typ publikacji :
Journal Article
MeSH Terms :
Dermatitis, Allergic Contact/*drug therapy
Dopamine Antagonists/*therapeutic use
Perphenazine/*therapeutic use
Animals ; Cytokines/metabolism ; Dermatitis, Allergic Contact/etiology ; Dopamine Antagonists/pharmacology ; Immunoglobulin G/metabolism ; Mast Cells/drug effects ; Mast Cells/immunology ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Oxazolone/toxicity ; Perphenazine/pharmacology ; Tetradecanoylphorbol Acetate/toxicity ; Th2 Cells/drug effects ; Th2 Cells/immunology
Czasopismo naukowe
Tytuł :
Laminarin Pretreatment Provides Neuroprotection against Forebrain Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Neuroinflammation in Aged Gerbils.
Autorzy :
Park JH; Department of Anatomy, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Korea.
Ahn JH; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee TK; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Park CW; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim B; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee JC; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, and Research Institute of Oral Sciences, College of Dentistry, Gangnung-Wonju National University, Gangneung, Gangwon 25457, Korea.
Shin MC; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Cho JH; Department of Emergency Medicine, and Institute of Medical Sciences, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
Lee CH; Department of Pharmacy, College of Pharmacy, Dancook University, Cheonan, Chungcheongnam 31116, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon 24252, Korea.
Won MH; Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon 24341, Korea.
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Źródło :
Marine drugs [Mar Drugs] 2020 Apr 15; Vol. 18 (4). Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*drug therapy
Glucans/*pharmacology
Inflammation/*metabolism
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Reperfusion Injury/*drug therapy
Animals ; Cytokines/metabolism ; Disease Models, Animal ; Gerbillinae ; Hippocampus/drug effects ; Male ; Nerve Tissue Proteins ; Neurons/drug effects ; Neurons/metabolism ; Neuroprotection ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Tat-Biliverdin Reductase A Exerts a Protective Role in Oxidative Stress-Induced Hippocampal Neuronal Cell Damage by Regulating the Apoptosis and MAPK Signaling.
Autorzy :
Kim SJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Shin MJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Yeo HJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yeo EJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi YJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Sohn EJ; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee KW; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Cho YJ; Department of Neurosurgery, Hallym University Medical Center, Chuncheon 24253, Korea.
Kim DS; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si 31538, Korea.
Eum WS; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research, Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 11; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 11.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Products, tat*/genetics
Oxidoreductases Acting on CH-CH Group Donors*/genetics
Apoptosis/*drug effects
MAP Kinase Signaling System/*drug effects
Oxidative Stress/*drug effects
Pyramidal Cells/*drug effects
Pyramidal Cells/*metabolism
Recombinant Fusion Proteins/*pharmacology
Animals ; Brain Ischemia/drug therapy ; Brain Ischemia/etiology ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Cell Line ; Disease Models, Animal ; Gerbillinae ; Hydrogen Peroxide/metabolism ; Male ; Neuroprotective Agents/pharmacology ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
MicroRNA-22 negatively regulates LPS-induced inflammatory responses by targeting HDAC6 in macrophages.
Autorzy :
Youn GS; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park JK; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee CY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Jang JH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Yun SH; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kwon HY; Department of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
Park J; Department of Biomedical Science and Research Institute for Bioscience & Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Apr; Vol. 53 (4), pp. 223-228.
Typ publikacji :
Journal Article
MeSH Terms :
Histone Deacetylase 6/*genetics
Histone Deacetylase 6/*metabolism
MicroRNAs/*genetics
Animals ; Cytokines/metabolism ; Inflammation/genetics ; Inflammation/metabolism ; Lipopolysaccharides/pharmacology ; Macrophages/metabolism ; Macrophages/physiology ; Mice ; MicroRNAs/metabolism ; NF-kappa B/metabolism ; RAW 264.7 Cells ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation.
Autorzy :
Choi M; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea. .
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 17; Vol. 10 (1), pp. 4887. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dermis/*metabolism
Glucose/*metabolism
Hair Follicle/*metabolism
Histones/*metabolism
Acetylation ; Animals ; Blotting, Western ; Cell Survival/physiology ; Dietary Carbohydrates/metabolism ; Female ; Glycolysis/physiology ; Meta-Analysis as Topic ; Mice, Inbred C57BL ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Nintedanib ameliorates animal model of dermatitis.
Autorzy :
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul, 05029, South Korea. .
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu, Seoul, 05836, South Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 11; Vol. 10 (1), pp. 4493. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dermatitis/*drug therapy
Dermatitis/*metabolism
Indoles/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Animals ; Biomarkers ; Biopsy ; Cell Line ; Cell Survival ; Dermatitis/etiology ; Dermatitis/pathology ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Gene Expression ; Immunoglobulin E/blood ; Immunoglobulin E/immunology ; Mice ; Oxazolone/adverse effects ; Skin/drug effects ; Skin/metabolism ; Skin/pathology ; Vascular Endothelial Growth Factor Receptor-1/genetics ; Vascular Endothelial Growth Factor Receptor-1/metabolism
Czasopismo naukowe
Tytuł :
Comprehensive analyses of safety and efficacy toward individualizing imatinib dosage in patients with chronic myeloid leukemia.
Autorzy :
Shin H; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea.; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Choi SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Kee KM; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Kim SH; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Yang SY; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea.
Jung SY; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea.; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Noh H; Department of Pharmacy, College of Pharmacy, Yonsei University, Incheon, South Korea.
Zang DY; Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
Kim DW; Leukemia Research Institute, The Catholic University of Korea, Seoul, South Korea. .; Department of Hematology, Catholic Hematology Hospital, Leukemia Research Institute, The Catholic University of Korea, 222 Banpo-Daero, Seocho-Gu, Seoul, 06591, Republic of Korea. .
Lee JI; Department of Pharmacy, College of Pharmacy, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, Seoul, 08826, Republic of Korea. .; Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Mar; Vol. 111 (3), pp. 417-426. Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article
MeSH Terms :
Precision Medicine*
Imatinib Mesylate/*administration & dosage
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Body Weight ; Female ; Humans ; Imatinib Mesylate/adverse effects ; Male ; Middle Aged ; Neutropenia/chemically induced ; Safety ; Thrombocytopenia/chemically induced ; Time Factors ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Differential roles of exogenous protein disulfide isomerase A3 on proliferating cell and neuroblast numbers in the normal and ischemic gerbils.
Autorzy :
Yoo DY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.; Department of Anatomy, College of Medicine, Soonchunhyang University, Cheonan, South Korea.
Cho SB; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, South Korea.
Jung HY; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Kim W; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Nam SM; Department of Anatomy, College of Veterinary Medicine, Konkuk University, Seoul, South Korea.
Kim JW; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Moon SM; Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, South Korea.
Choi SY; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
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Źródło :
Brain and behavior [Brain Behav] 2020 Mar; Vol. 10 (3), pp. e01534. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*pathology
Cell Proliferation/*drug effects
Hippocampus/*drug effects
Neural Stem Cells/*drug effects
Neurogenesis/*drug effects
Protein Disulfide-Isomerases/*pharmacology
Animals ; Cell Count ; Gerbillinae ; Male ; Phosphorylation
Czasopismo naukowe
Tytuł :
PEP-1-GLRX1 protein exhibits anti-inflammatory effects by inhibiting the activation of MAPK and NF-κB pathways in Raw 264.7 cells.
Autorzy :
Shin MJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung 25457, Korea.
Choi YJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Cha HJ; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Lee SH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252; Genesen Inc., Seoul 06181, Korea.
Park J; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Han KH; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Eum WS; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Korea.
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Źródło :
BMB reports [BMB Rep] 2020 Feb; Vol. 53 (2), pp. 106-111.
Typ publikacji :
Journal Article
MeSH Terms :
Peptides*
Anti-Inflammatory Agents/*pharmacology
Cysteamine/*analogs & derivatives
Glutaredoxins/*pharmacology
Inflammation/*metabolism
Mitogen-Activated Protein Kinases/*antagonists & inhibitors
NF-kappa B/*metabolism
Animals ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Edema/chemically induced ; Edema/metabolism ; Edema/therapy ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Mitogen-Activated Protein Kinases/metabolism ; Nitric Oxide Synthase Type II/antagonists & inhibitors ; Nitric Oxide Synthase Type II/metabolism ; Phosphorylation ; RAW 264.7 Cells ; Signal Transduction/drug effects ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł :
Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine.
Autorzy :
Tran HQ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Saito K; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Toyoake, Japan. Electronic address: .
Tran TV; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Phan DH; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Sharma N; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.
Choi SY; Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chunchon, 24252, Republic of Korea.
Jeong JH; Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
Jang CG; Department of Pharmacology, School of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Cheong JH; Department of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Sciences, Toyoake, Japan; Japanese Drug Organization of Appropriate Use and Research, Nagoya, Japan.
Kim HC; Neuropsychopharmacology and Toxicology Program, BK21 PLUS Project, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2020 Feb; Vol. 136, pp. 110986. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antimanic Agents/*therapeutic use
Bipolar Disorder/*drug therapy
Indoleamine-Pyrrole 2,3,-Dioxygenase/*metabolism
Lithium/*therapeutic use
Valproic Acid/*therapeutic use
Animals ; Bipolar Disorder/chemically induced ; Bipolar Disorder/metabolism ; Calcium/metabolism ; Dextroamphetamine ; Glutathione Peroxidase/metabolism ; Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics ; Locomotion/drug effects ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/drug effects ; Mitochondria/metabolism ; Prefrontal Cortex/pathology ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
2-deoxy-d-glucose Ameliorates Animal Models of Dermatitis.
Autorzy :
Choi SY; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Heo MJ; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Lee C; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Choi YM; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
An IS; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
Bae S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
An S; Research Institute for Molecular-Targeted Drugs, Department of Cosmetics Engineering, Konkuk University, Seoul 05029, Korea.
Jung JH; Korea Institute of Dermatological Science, GeneCellPharm Corporation, 375 Munjeong 2(i)-dong, Songpa-gu Seoul 05836, Korea.
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Źródło :
Biomedicines [Biomedicines] 2020 Jan 24; Vol. 8 (2). Date of Electronic Publication: 2020 Jan 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Could Defatted Mealworm ( Tenebrio molitor ) and Mealworm Oil Be Used as Food Ingredients?
Autorzy :
Son YJ; Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung Institute of Natural Products, Gangneung, Gangwon-do 25451, Korea.; Department of Food and Nutrition and Research Institute of Human Ecology, Seoul National University, Seoul 08826, Korea.
Choi SY; Sempio, Seoul 04557, Korea.
Hwang IK; Department of Food and Nutrition and Research Institute of Human Ecology, Seoul National University, Seoul 08826, Korea.
Nho CW; Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung Institute of Natural Products, Gangneung, Gangwon-do 25451, Korea.
Kim SH; Department of Culinary Arts, Kyungmin University, Uijeongbu, Gyeonggi-do 11618, Korea.
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Źródło :
Foods (Basel, Switzerland) [Foods] 2020 Jan 02; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 02.
Typ publikacji :
Journal Article
Czasopismo naukowe

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