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Wyszukujesz frazę ""Cholecystokinin"" wg kryterium: Temat


Starter badań:

Tytuł:
Prediction of Cholecystokinin-Secretory Peptides Using Bidirectional Long Short-term Memory Model Based on Transfer Learning and Hierarchical Attention Network Mechanism.
Autorzy:
Liu J; College of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Chen P; College of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Song H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Zhang P; Joint Center for Translational Medicine, Southern Medical University Affiliated Fengxian Hospital, Shanghai 201499, China.
Wang M; Joint Center for Translational Medicine, Southern Medical University Affiliated Fengxian Hospital, Shanghai 201499, China.
Sun Z; Joint Center for Translational Medicine, Southern Medical University Affiliated Fengxian Hospital, Shanghai 201499, China.
Guan X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Sep 11; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*
Machine Learning*
Humans ; Peptides/pharmacology ; Receptors, Cholecystokinin
Czasopismo naukowe
Tytuł:
Cholecystokinin (CCK) and its receptors (CCK1R and CCK2R) in chickens: functional analysis and tissue expression.
Autorzy:
Wan Y; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Deng Q; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Zhou Z; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Deng Y; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Zhang J; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Li J; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China.
Wang Y; Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, PR China. Electronic address: .
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Źródło:
Poultry science [Poult Sci] 2023 Jan; Vol. 102 (1), pp. 102273. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cholecystokinin*/genetics
Cholecystokinin*/metabolism
Chickens*/genetics
Chickens*/metabolism
Male ; Animals ; Receptors, Cholecystokinin/genetics ; Receptors, Cholecystokinin/metabolism ; Intestines ; Ileum/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Treatment with a Cholecystokinin Receptor Antagonist, Proglumide, Improves Efficacy of Immune Checkpoint Antibodies in Hepatocellular Carcinoma.
Autorzy:
Shivapurkar N; Department of Medicine, Georgetown University, Washington, DC 20007, USA.
Gay MD; Department of Medicine, Georgetown University, Washington, DC 20007, USA.
He AR; Department of Oncology, Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA.
Chen W; Department of Medicine, Georgetown University, Washington, DC 20007, USA.
Golnazar S; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20057, USA.
Cao H; Department of Medicine, Georgetown University, Washington, DC 20007, USA.
Duka T; Department of Medicine, Georgetown University, Washington, DC 20007, USA.
Kallakury B; Department of Pathology, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
Vasudevan S; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20057, USA.
Smith JP; Department of Medicine, Georgetown University, Washington, DC 20007, USA.; Department of Oncology, Georgetown University Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 11; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/immunology
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/immunology
Liver Neoplasms*/metabolism
Proglumide*/pharmacology
Receptors, Cholecystokinin*/antagonists & inhibitors
Immune Checkpoint Inhibitors*/immunology
Animals ; Mice ; Cholecystokinin ; Fibrosis
Czasopismo naukowe
Tytuł:
Two parabrachial Cck neurons involved in the feedback control of thirst or salt appetite.
Autorzy:
Matsuda T; Homeostatic Mechanism Research Unit, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Kanagawa 226-8503, Japan.
Kobayashi K; Section of Viral Vector Development, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.
Kobayashi K; Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima, Fukushima 960-1295, Japan.
Noda M; Homeostatic Mechanism Research Unit, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Kanagawa 226-8503, Japan. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2024 Jan 23; Vol. 43 (1), pp. 113619. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Appetite*/physiology
Cholecystokinin*
Sodium Chloride, Dietary ; Feedback ; Thirst/physiology ; Sodium Chloride ; GABAergic Neurons ; Water
Czasopismo naukowe
Tytuł:
Identification and target of action of cholecystokinin-releasing peptides from simulated digestion hydrolysate of wheat protein.
Autorzy:
Song H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Wang Q; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Shao Z; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Wang X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Cao H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Huang K; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Guan X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
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Źródło:
Journal of the science of food and agriculture [J Sci Food Agric] 2024 Jan 15; Vol. 104 (1), pp. 295-302. Date of Electronic Publication: 2023 Aug 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cholecystokinin*/metabolism
Triticum*/metabolism
Mice ; Animals ; Cell Line ; Peptides/pharmacology ; Receptors, Calcium-Sensing/metabolism ; Digestion
Czasopismo naukowe
Tytuł:
A Cholecystokinin Analogue Ameliorates Cognitive Deficits and Regulates Mitochondrial Dynamics via the AMPK/Drp1 Pathway in APP/PS1 Mice.
Autorzy:
Hao L; Zhenqiang Zhang, Christian Holscher and Zijuan Zhang, Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan province, China. E-mail: , E-mail: , and E-mail: . Orcid ID of C. Hölscher: 0000-0002-8159-3260.
Shi M
Ma J
Shao S
Yuan Y
Liu J
Yu Z
Zhang Z
Hölscher C
Zhang Z
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Źródło:
The journal of prevention of Alzheimer's disease [J Prev Alzheimers Dis] 2024; Vol. 11 (2), pp. 382-401.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Cholecystokinin*/analogs & derivatives
Cholecystokinin*/pharmacology
Cholecystokinin*/therapeutic use
Cognitive Dysfunction*/drug therapy
Mitochondrial Dynamics*/drug effects
Animals ; Humans ; Mice ; AMP-Activated Protein Kinases/metabolism ; Amyloid beta-Peptides/metabolism ; Cognition ; Dynamins/drug effects ; Dynamins/metabolism ; Mice, Transgenic
Czasopismo naukowe
Tytuł:
Satiety: a gut-brain-relationship.
Autorzy:
Barakat GM; Biological and Chemical Sciences Department, School of Arts and Sciences, Lebanese International University, Beirut, Lebanon. .
Ramadan W; Biological and Chemical Sciences Department, School of Arts and Sciences, Lebanese International University, Beirut, Lebanon.; Nutrition and Food Sciences Department, School of Arts and Sciences, Lebanese International University, Beirut, Lebanon.
Assi G; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.
Khoury NBE; Psychology department, Faculty of Arts and Sciences, University of Balamand, Balamand, Lebanon.
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Źródło:
The journal of physiological sciences : JPS [J Physiol Sci] 2024 Feb 17; Vol. 74 (1), pp. 11. Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cholecystokinin*/metabolism
Glucagon-Like Peptide 1*
Peptide YY/metabolism ; Brain/metabolism ; Neurotransmitter Agents
Czasopismo naukowe
Tytuł:
Photodynamic Activation of the Cholecystokinin 1 Receptor with Tagged Genetically Encoded Protein Photosensitizers: Optimizing the Tagging Patterns.
Autorzy:
Li Y; Institute of Cell Biology, Beijing Normal University, Beijing, China.
Cui ZJ; Institute of Cell Biology, Beijing Normal University, Beijing, China.
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Źródło:
Photochemistry and photobiology [Photochem Photobiol] 2022 Sep; Vol. 98 (5), pp. 1215-1228. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Photosensitizing Agents*/metabolism
Photosensitizing Agents*/pharmacology
Receptors, Cholecystokinin*/genetics
Receptors, Cholecystokinin*/metabolism
Calcium ; Cholecystokinin ; Fura-2 ; Proteins ; Singlet Oxygen/metabolism ; Uric Acid
Czasopismo naukowe
Tytuł:
Discovery of once-weekly, peptide-based selective GLP-1 and cholecystokinin 2 receptors co-agonizts.
Autorzy:
Zhou F; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Song P; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Tang X; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Yang Q; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Zhou S; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Xu R; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Fang T; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China.
Jia Z; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530001, PR China. Electronic address: .
Han J; School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, PR China; Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Ministry of Education, Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Guangxi Medical University, Nanning, Guangxi 530021, PR China. Electronic address: .
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Źródło:
Peptides [Peptides] 2022 Jul; Vol. 153, pp. 170811. Date of Electronic Publication: 2022 May 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*
Glucagon-Like Peptide-1 Receptor*/agonists
Glucagon-Like Peptide-1 Receptor*/drug effects
Glucagon-Like Peptide-1 Receptor*/metabolism
Hypoglycemic Agents*/pharmacology
Peptides*/chemistry
Peptides*/pharmacology
Receptor, Cholecystokinin B*/agonists
Receptor, Cholecystokinin B*/drug effects
Receptor, Cholecystokinin B*/metabolism
Animals ; Anti-Obesity Agents/pharmacology ; Cholecystokinin/metabolism ; Glucagon-Like Peptide 1/metabolism ; Glucose ; Mice ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
The expression of the gastrin/cholecystokinin (GAST/CCK) family and their receptors (CCKAR/CCKBR) in the chicken changes in response to quantitative restriction and reveals a functional role of CCK in the crop.
Autorzy:
Jiao Y; The Roslin Institute, University of Edinburgh, EH25 9RG Scotland, UK. Electronic address: .
Wilson PW; The Roslin Institute, University of Edinburgh, EH25 9RG Scotland, UK. Electronic address: .
Reid AMA; The Roslin Institute, University of Edinburgh, EH25 9RG Scotland, UK. Electronic address: .
Dunn IC; The Roslin Institute, University of Edinburgh, EH25 9RG Scotland, UK. Electronic address: .
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Źródło:
General and comparative endocrinology [Gen Comp Endocrinol] 2022 Jun 01; Vol. 321-322, pp. 114024. Date of Electronic Publication: 2022 Mar 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*
Receptors, Cholecystokinin*/genetics
Receptors, Cholecystokinin*/metabolism
Animals ; Chickens/metabolism ; Gastrins/metabolism ; Receptor, Cholecystokinin B/genetics
Czasopismo naukowe
Tytuł:
Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses.
Autorzy:
Su J; Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Huang F; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, P.R. China. Electronic address: .
Tian Y; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Tian R; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Qianqian G; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Bello ST; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, P.R. China.
Zeng D; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Jendrichovsky P; Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Lau CG; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China.
Xiong W; Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; City University of Hong Kong Shenzhen Research Institute, Shenzhen, P.R. China.
Yu D; Key Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, P.R. China.
Tortorella M; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, P.R. China; Key Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, P.R. China.
Chen X; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; City University of Hong Kong Shenzhen Research Institute, Shenzhen, P.R. China. Electronic address: .
He J; Department of Neuroscience, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, P.R. China; City University of Hong Kong Shenzhen Research Institute, Shenzhen, P.R. China. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2023 Dec 26; Vol. 42 (12), pp. 113467. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*/genetics
Cholecystokinin*/metabolism
Entorhinal Cortex*/metabolism
CA3 Region, Hippocampal*/physiology
CA1 Region, Hippocampal*/physiology
CA2 Region, Hippocampal*/physiology
Spatial Learning*/physiology
Neuronal Plasticity*
Synapses/physiology ; Animals ; Mice ; Mice, Knockout ; Long-Term Potentiation
Czasopismo naukowe
Tytuł:
In vitro gastrointestinal digestion of highland barley protein: identification and characterization of novel bioactive peptides involved in gut cholecystokinin secretion.
Autorzy:
Huang K; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Wang Q; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Song H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Cao H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
Guan X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai, China.
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Źródło:
Journal of the science of food and agriculture [J Sci Food Agric] 2023 Dec; Vol. 103 (15), pp. 7869-7876. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cholecystokinin*/metabolism
Hordeum*/metabolism
Mice ; Animals ; Secretagogues ; Peptides/pharmacology ; Proteins ; Digestion
Czasopismo naukowe
Tytuł:
Effect of GRK4 on renal gastrin receptor regulation in hypertension.
Autorzy:
Xia X; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.; Department of Stem Cell and Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, Chongqing, China.; Central Laboratory, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing, China.
Zeng Y; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.; Department of Cardiology, Raffles Hospital Chongqing, Chongqing, China.
Li Z; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Luo H; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Wang W; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
He Y; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Lu B; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Guo J; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Chen K; Department of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, China.; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, P.R. China.
Xu X; Department of Stem Cell and Regenerative Medicine, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Third Military Medical University, Chongqing, China.; Central Laboratory, State Key Laboratory of Trauma, Burn and Combined Injury, Daping Hospital, Army Medical University, Chongqing, China.
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Źródło:
Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2023 Dec 31; Vol. 45 (1), pp. 2245580.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Cholecystokinin B*
Hypertension*/genetics
Animals ; Mice ; Gastrins/pharmacology ; RNA, Small Interfering ; Sodium ; Adenosine Triphosphatases
Czasopismo naukowe
Tytuł:
Deterioration of apatite orientation in the cholecystokinin B receptor gene (Cckbr)-deficient mouse femurs.
Autorzy:
Mihara Y; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Ishimoto T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1, Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Ozasa R; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1, Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Omura T; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Yamato Y; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Yamada T; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Okamoto A; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Matsuyama Y; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan. .
Nakano T; Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1, Yamada-Oka, Suita, Osaka, 565-0871, Japan. .
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Źródło:
Journal of bone and mineral metabolism [J Bone Miner Metab] 2023 Nov; Vol. 41 (6), pp. 752-759. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Cholecystokinin B*
Achlorhydria*
Mice ; Animals ; Apatites ; Bone and Bones ; Bone Density ; Femur/diagnostic imaging
Czasopismo naukowe
Tytuł:
Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1-induced satiation.
Autorzy:
Vana V; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
Laerke MK; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Rehfeld JF; Department of Clinical Biochemistry (KB3011), Rigshospitalet, Copenhagen, Denmark.
Arnold M; Physiology and Behavior Laboratory, Department of Health Sciences and Technology, ETH Zurich, Schwerzenbach, Switzerland.
Dmytriyeva O; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
Langhans W; Physiology and Behavior Laboratory, Department of Health Sciences and Technology, ETH Zurich, Schwerzenbach, Switzerland.
Schwartz TW; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
Hansen HS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2022 Feb; Vol. 24 (2), pp. 268-280. Date of Electronic Publication: 2021 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*
Glucagon-Like Peptide 1*
Animals ; Eating ; Humans ; Mice ; Receptors, Cholecystokinin ; Satiation/physiology ; Vagus Nerve/physiology
Czasopismo naukowe
Tytuł:
Optimized LC-MS/MS Method for the Detection of ppCCK(21-44): A Surrogate to Monitor Human Cholecystokinin Secretion.
Autorzy:
Foreman RE; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.; Peptidomics and Proteomics Core Facility, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
Miedzybrodzka EL; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
Eiríksson FF; Faculty of Pharmaceutical Sciences, University of Iceland, 107 Reykjavík, Iceland.
Thorsteinsdóttir M; Faculty of Pharmaceutical Sciences, University of Iceland, 107 Reykjavík, Iceland.
Bannon C; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
Wheller R; Drug Development Solutions, Part of Alliance Pharma Ltd., Fordham CB7 5WW, U.K.
Reimann F; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
Gribble FM; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
Kay RG; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.; Peptidomics and Proteomics Core Facility, Level 4, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, U.K.
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Źródło:
Journal of proteome research [J Proteome Res] 2023 Sep 01; Vol. 22 (9), pp. 2950-2958. Date of Electronic Publication: 2023 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*
Tandem Mass Spectrometry*
Humans ; Chromatography, Liquid ; Biological Transport ; Bodily Secretions
Czasopismo naukowe
Tytuł:
Cholecystokinin neurons in mouse suprachiasmatic nucleus regulate the robustness of circadian clock.
Autorzy:
Xie L; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Shanghai 200031, China.
Xiong Y; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Shanghai 200031, China.
Ma D; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Shi K; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Chen J; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Yang Q; Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yan J; Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China; Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai 201210, China; School of Future Technology, University of Chinese Academy of Sciences, Beijing 101408, China. Electronic address: .
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Źródło:
Neuron [Neuron] 2023 Jul 19; Vol. 111 (14), pp. 2201-2217.e4. Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholecystokinin*
Circadian Clocks*
Animals ; Mice ; Circadian Rhythm/physiology ; Mammals/metabolism ; Neurons/physiology ; Photoperiod ; Suprachiasmatic Nucleus/metabolism ; Vasoactive Intestinal Peptide/metabolism
Czasopismo naukowe
Tytuł:
A sex-specific thermogenic neurocircuit induced by predator smell recruiting cholecystokinin neurons in the dorsomedial hypothalamus.
Autorzy:
Jovanovic P; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Pool AH; Department of Neuroscience, Department of Anesthesiology and Pain Management, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Morones N; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Wang Y; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Novinbakht E; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Keshishian N; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Jang K; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA.
Oka Y; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Riera CE; Center for Neural Science and Medicine, Department of Biomedical Sciences, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA. .; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA. .; Department of Neurology, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA, 90048, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Aug 15; Vol. 14 (1), pp. 4937. Date of Electronic Publication: 2023 Aug 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Smell*
Cholecystokinin*
Male ; Mice ; Female ; Animals ; Thermogenesis/physiology ; Neurons/physiology ; Hypothalamus
Czasopismo naukowe
Tytuł:
In vitro gastrointestinal digestion of buckwheat ( Fagopyrum esculentum Moench) protein: release and structural characteristics of novel bioactive peptides stimulating gut cholecystokinin secretion.
Autorzy:
Song H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai 200093, China.
Wang Q; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .
Shao Z; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .
Wang X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .
Cao H; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai 200093, China.
Huang K; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai 200093, China.
Sun Q; Fengxian Central Hospital, Shanghai 201499, China. .
Sun Z; Fengxian Central Hospital, Shanghai 201499, China. .
Guan X; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. .; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai 200093, China.
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Źródło:
Food & function [Food Funct] 2023 Aug 14; Vol. 14 (16), pp. 7469-7477. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cholecystokinin*/metabolism
Fagopyrum*/metabolism
Peptides ; Proteins ; Digestion
Czasopismo naukowe
Tytuł:
Development of Highly Potent Clinical Candidates for Theranostic Applications against Cholecystokinin-2 Receptor Positive Cancers.
Autorzy:
Corlett A; Department of Nuclear Medicine, The Royal Melbourne Hospital, Parkville, Victoria, 3000, Australia.
Pinson JA; The Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Rahimi MN; The Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Zuylekom JV; Models of Cancer Translational Research Centre, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Cullinane C; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.; The Centre for Molecular Imaging and Translational Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Blyth B; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.; Models of Cancer Translational Research Centre, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Thompson PE; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University (Parkville Campus), Parkville, Victoria 3052, Australia.
Hutton CA; School of Chemistry, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Roselt PD; Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; The Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Haskali MB; Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; The Radiopharmaceutical Research Laboratory, The Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Aug 10; Vol. 66 (15), pp. 10289-10303. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptor, Cholecystokinin B*/metabolism
Neoplasms*/drug therapy
Precision Medicine ; Tissue Distribution ; Cell Line, Tumor ; Peptides/chemistry
Czasopismo naukowe

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