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Wyszukujesz frazę ""Cholestenone 5 alpha-Reductase"" wg kryterium: Temat

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Tytuł:
mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia.
Autorzy:
Sánchez P; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Serrano Falcón C; Hospital of Guadix, 18500 Granada, Spain.
Martínez Rodríguez S; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Torres JM; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
Serrano S; Department of Dermatology, Faculty of Medicine, University of Granada, 18012 Granada, Spain.
Ortega E; Department of Biochemistry, Molecular Biology and Immunology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 14; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestenone 5 alpha-Reductase*/genetics
Prostatic Neoplasms*/genetics
Male ; Humans ; Aromatase/genetics ; Isoenzymes/therapeutic use ; RNA, Messenger/genetics ; Hair ; Alopecia/genetics ; Alopecia/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur.
Autorzy:
Agarwal D; Institute of Fisheries Post Graduate Studies, TNJFU, Kazhipattur, India.
Kumar G; College of Fisheries, Gumla, Phasia, India.
Ashraf Rather M; Division of Fish Genetics and Biotechnology, Faculty of Fisheries, SKUAST-Kashmir, Srinagar, India. .
Ahmad I; Division of Fish Genetics and Biotechnology, Faculty of Fisheries, SKUAST-Kashmir, Srinagar, India.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 09; Vol. 13 (1), pp. 19553. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestenone 5 alpha-Reductase*/metabolism
Catfishes*/genetics
Catfishes*/metabolism
Male ; Animals ; Female ; Humans ; DNA, Complementary/genetics ; NADP/metabolism ; Amino Acid Sequence ; Testosterone/metabolism ; Dihydrotestosterone/metabolism ; Steroids/metabolism ; Cloning, Molecular ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/genetics ; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells.
Autorzy:
Di Luigi L; Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
Antinozzi C; Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
Duranti G; Unit of Biochemistry and Molecular Biology, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
Dimauro I; Unit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
Sgrò P; Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 12; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Testosterone*/metabolism
Receptors, Androgen*/genetics
Receptors, Androgen*/metabolism
Male ; Female ; Humans ; Sex Characteristics ; Androgens/metabolism ; Oxidoreductases/metabolism ; Cholestenone 5 alpha-Reductase/genetics ; Muscle, Skeletal/metabolism ; Sex Chromosomes/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
5-α reductase inhibition by Epilobioum fleischeri extract modulates facial microbiota structure.
Autorzy:
Sfriso R; Personal Care, DSM Nutritional Products, Kaiseraugst, Switzerland.
Claypool J; Nutrition Innovation Center, DSM Nutritional Products, Lexington, Massachusetts, USA.
Roche M; Newtone Technologies, Lyon, France.
Imfeld D; Personal Care, DSM Nutritional Products, Kaiseraugst, Switzerland.
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Źródło:
International journal of cosmetic science [Int J Cosmet Sci] 2022 Aug; Vol. 44 (4), pp. 440-452. Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Cholestenone 5 alpha-Reductase*
Microbiota*/genetics
Bacteria ; Female ; Humans ; Plant Extracts/pharmacology ; RNA, Ribosomal, 16S/genetics ; Skin/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing.
Autorzy:
Bar-Sadeh B; Faculty of Biology, Technion-Israel Institute of Technology, 32000, Haifa, Israel.
Amichai OE; Faculty of Biology, Technion-Israel Institute of Technology, 32000, Haifa, Israel.
Pnueli L; Faculty of Biology, Technion-Israel Institute of Technology, 32000, Haifa, Israel.
Begum K; Department of Anthropology, Durham University, Durham, DH1 3LE, UK.
Leeman G; School of Biosciences, University of Nottingham, Nottingham, LE12 5RD, UK.
Emes RD; School of Veterinary Medicine and Sciences, University of Nottingham, Nottingham, LE12 5RD, UK.
Stöger R; School of Biosciences, University of Nottingham, Nottingham, LE12 5RD, UK.
Bentley GR; Department of Anthropology, Durham University, Durham, DH1 3LE, UK.
Melamed P; Faculty of Biology, Technion-Israel Institute of Technology, 32000, Haifa, Israel. .
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Źródło:
BMC biology [BMC Biol] 2022 Jan 07; Vol. 20 (1), pp. 11. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholestenone 5 alpha-Reductase*/genetics
Cholestenone 5 alpha-Reductase*/metabolism
Kisspeptins*/genetics
Kisspeptins*/metabolism
3-Oxo-5-alpha-Steroid 4-Dehydrogenase/*metabolism
Membrane Proteins/*metabolism
Adaptation, Physiological ; Animals ; Epigenesis, Genetic ; Female ; Gonadotropin-Releasing Hormone/genetics ; Gonadotropin-Releasing Hormone/metabolism ; Humans ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice.
Autorzy:
Fujita T; Department of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu 525-8577, Japan.
Aoyama T; Department of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu 525-8577, Japan.
Uemura T; Hayashikane Sangyo Co., Ltd., Yamaguchi 750-8608, Japan.
Takeshita S; Hayashikane Sangyo Co., Ltd., Yamaguchi 750-8608, Japan.
Yamasaki T; Hayashikane Sangyo Co., Ltd., Yamaguchi 750-8608, Japan.
Heijou H; Hayashikane Sangyo Co., Ltd., Yamaguchi 750-8608, Japan.
Morimoto K; Department of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu 525-8577, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 21; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Prostatic Hyperplasia*/drug therapy
Prostatic Hyperplasia*/chemically induced
Male ; Humans ; Cholestenone 5 alpha-Reductase ; Testosterone/metabolism ; Dihydrotestosterone/metabolism
SCR Organism:
Trapa
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protective effects of combination of Stauntonia hexaphylla and Cornus officinalis on testosterone-induced benign prostatic hyperplasia through inhibition of 5α- reductase type 2 and induced cell apoptosis.
Autorzy:
Karunasagara S; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea.
Hong GL; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea.
Jung DY; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea.
Kim KH; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea.
Cho K; Department of Pharmacy, College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Jung JY; Department of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon, Republic of Korea.
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Źródło:
PloS one [PLoS One] 2020 Aug 13; Vol. 15 (8), pp. e0236879. Date of Electronic Publication: 2020 Aug 13 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Cholestenone 5 alpha-Reductase/*chemistry
Plant Extracts/*pharmacology
Prostatic Hyperplasia/*prevention & control
Protective Agents/*therapeutic use
5-alpha Reductase Inhibitors/chemistry ; 5-alpha Reductase Inhibitors/pharmacology ; 5-alpha Reductase Inhibitors/therapeutic use ; Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cholestenone 5 alpha-Reductase/metabolism ; Cornus/chemistry ; Cornus/metabolism ; Down-Regulation/drug effects ; Humans ; Male ; Plant Extracts/chemistry ; Plant Extracts/therapeutic use ; Plant Leaves/chemistry ; Plant Leaves/metabolism ; Prostate-Specific Antigen/blood ; Prostatic Hyperplasia/etiology ; Protective Agents/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Ranunculales/chemistry ; Ranunculales/metabolism ; Rats ; Rats, Sprague-Dawley ; Testosterone Propionate/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sinomenine Hydrochloride Can Ameliorate Benign Prostatic Hyperplasia by Lowering the 5α-Reductase 2 Level and Regulating the Balance between the Proliferation and Apoptosis of Cells.
Autorzy:
Fan MS; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Xia YF; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Ye RH; Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming 650500, China.
Sun ZR; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Wang MY; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
An MF; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Zhang SS; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Zhang LJ; School of Basic Medicine, Yunnan University of Chinese Medicine Chinese, Kunming 650500, China.
Zhao YL; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, School of Chemical Science and Technology, Yunnan University, Kunming 650500, China.
Xiang ZM; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.
Sheng J; Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650224, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650224, China.; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Kunming 650051, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 13; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Prostatic Hyperplasia*/drug therapy
Prostatic Hyperplasia*/metabolism
Animals ; Humans ; Male ; Mice ; Apoptosis ; Cell Proliferation ; Cholestenone 5 alpha-Reductase/metabolism ; Matrix Metalloproteinase 2 ; Membrane Proteins ; Plant Extracts/pharmacology ; Proliferating Cell Nuclear Antigen ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Quality of Life ; Testosterone/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microneedle mediated transdermal delivery of β-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia.
Autorzy:
Prabahar K; Department of Pharmacy Practice, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.; Department of Pharmacy Practice, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute, Velappanchavadi, Chennai, Tamil Nadu, India.
Udhumansha U; C.L. Baid Metha College of Pharmacy, Chennai, India.
Elsherbiny N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Qushawy M; Department of Pharmaceutics, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.; Department of Pharmaceutics, Faculty of Pharmacy, Sinai University, Alarish, North Sinai, Egypt.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 3022-3034.
Typ publikacji:
Journal Article
MeSH Terms:
Chitosan*
Drug Carriers*
Alopecia/drug therapy ; Androgens ; Animals ; Cholestenone 5 alpha-Reductase ; Excipients ; Glycosides ; Lipids ; Liposomes ; Nanoparticles ; Rats ; Sitosterols ; Testosterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of some medicinal plant extracts on dermal papilla cells.
Autorzy:
Wisuitiprot V; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, Thailand.; Cosmetics and Natural Products Research Center, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
Ingkaninan K; Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
Wisuitiprot W; Sirindhorn College of Public Health Phitsanulok, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Phitsanulok, Thailand.
Srivilai J; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of Phayao, Phayao, Thailand.
Chakkavittumrong P; Department of Internal Medicine, Faculty of Medicine, Thammasat University, Bangkok, Thailand.
Waranuch N; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, Thailand.; Cosmetics and Natural Products Research Center, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2022 Nov; Vol. 21 (11), pp. 6109-6117. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Plants, Medicinal*/metabolism
Humans ; Androgens ; Testosterone/metabolism ; Alopecia/drug therapy ; Alopecia/metabolism ; Cells, Cultured ; Cholestenone 5 alpha-Reductase/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/metabolism ; Hair Follicle
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gamma Irradiated Rhodiola sachalinensis Extract Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia by Downregulating 5-Alpha Reductase and Restoring Testosterone in Rats.
Autorzy:
Xin Q; Key Laboratory of Changbai Mountain Biological Resources and Functional Molecular Education, Yanbian University, Yanji 133002, China. .
Kwon MJ; Division of Efficiency Evaluation of Biomolecules, PSA Co., Ltd., Daejeon 35365, Korea. .
Lee JW; Division of Efficiency Evaluation of Biomolecules, PSA Co., Ltd., Daejeon 35365, Korea. .
Kim KS; Greenpia Technology Inc., Yeoju-si 12619, Gyeonggi-do, Korea. .
Chen H; Suite 18B Sea View Plaza, 18 Tai Zi Road Shekou, Shenzhen 518067, China. .
Campos MG; Observatory of Herb-Drug Interactions, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, 3000-370 Coimbra, Portugal. .; Coimbra Chemistry Centre (CQC, FCT Unit 313) (FCTUC), University of Coimbra, Rua Larga, 3000-370 Coimbra, Portugal. .
Tundis R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, Italy. .
Cui CB; Key Laboratory of Changbai Mountain Biological Resources and Functional Molecular Education, Yanbian University, Yanji 133002, China. .
Cho YH; Department of Pharmaceutics and Biotechnology, Konyang University, Daejeon 35365, Korea. .
Cao H; Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd., Hengqin New Area, Zhuhai 519031, China. hui_.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. hui_.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Nov 04; Vol. 24 (21). Date of Electronic Publication: 2019 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Gamma Rays*
Cholestenone 5 alpha-Reductase/*metabolism
Plant Extracts/*chemistry
Plant Extracts/*therapeutic use
Prostatic Hyperplasia/*drug therapy
Rhodiola/*chemistry
Testosterone/*metabolism
Testosterone/*toxicity
Animals ; Cholestenone 5 alpha-Reductase/genetics ; Male ; Prostatic Hyperplasia/blood ; Rats ; Rats, Sprague-Dawley ; Testosterone/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel 4-Azapregnene Derivatives as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies.
Autorzy:
Brito V; Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Santos AO; Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Alves G; Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Almeida P; Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Silvestre S; Health Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Sep 19; Vol. 27 (18). Date of Electronic Publication: 2022 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Receptors, Androgen*/metabolism
Androgens/pharmacology ; Azasteroids/pharmacology ; Cell Line, Tumor ; Cell Proliferation ; Cholestenone 5 alpha-Reductase/metabolism ; Drug Screening Assays, Antitumor ; Estrogen Receptor alpha ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Connarus semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway.
Autorzy:
Jang WY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Kim DS; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Park SH; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Yoon JH; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Shin CY; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Huang L; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Nang K; Forestry Administration, Phnom Penh 120206, Cambodia.
Kry M; Forestry Administration, Phnom Penh 120206, Cambodia.
Byun HW; National Institute of Biological Resources, Environmental Research Complex, Incheon 22689, Korea.
Lee BH; National Institute of Biological Resources, Environmental Research Complex, Incheon 22689, Korea.
Lee S; National Institute of Biological Resources, Environmental Research Complex, Incheon 22689, Korea.
Lee J; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 24; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Connaraceae*
Alopecia/chemically induced ; Animals ; Apoptosis ; Cholestenone 5 alpha-Reductase ; Hair Follicle ; Male ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparative application of testosterone undecanoate and/or testosterone propionate in induction of benign prostatic hyperplasia in Wistar rats.
Autorzy:
An J; College of Pharmacy, Sahmyook University, Seoul, Korea.; College of PADAM Natural Material Research Institute, Sahmyook University, Seoul, Korea.
Kong H; College of PADAM Natural Material Research Institute, Sahmyook University, Seoul, Korea.; College of Animal Biotechnology & Resource, Sahmyook University, Seoul, Korea.
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Źródło:
PloS one [PLoS One] 2022 May 18; Vol. 17 (5), pp. e0268695. Date of Electronic Publication: 2022 May 18 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prostatic Hyperplasia*/drug therapy
Testosterone Propionate*
Animals ; Cholestenone 5 alpha-Reductase ; Dihydrotestosterone ; Humans ; Male ; Rats ; Rats, Wistar ; Reproducibility of Results ; Testosterone/analogs & derivatives ; Testosterone/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona grandis L.f. Leaf Extract.
Autorzy:
Insumrong K; Department of Chemistry, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand.
Ingkaninan K; Centre of Excellence in Cannabis Research, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Waranuch N; Cosmetics and Natural Products Research Center and Center of Excellence for Innovation in Chemistry, Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand.
Tanuphol N; Centre of Excellence in Cannabis Research, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Wisuitiprot W; Department of Thai Traditional Medicine, Sirindhorn College of Public Health, Phitsanulok 65130, Thailand.
Promgool T; Cosmetics and Natural Products Research Center and Center of Excellence for Innovation in Chemistry, Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand.
Suphrom N; Department of Chemistry, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand.; Department of Chemistry, Faculty of Science and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Apr 30; Vol. 27 (9). Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Lamiaceae*
Verbenaceae*
3-Oxo-5-alpha-Steroid 4-Dehydrogenase ; 5-alpha Reductase Inhibitors/pharmacology ; Cholestenone 5 alpha-Reductase ; Chromatography, High Pressure Liquid ; Enzyme Inhibitors/pharmacology ; Hexanes ; Plant Extracts/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primary Amenorrhea Due to Anatomical Abnormalities of the Reproductive Tract: Molecular Insight.
Autorzy:
Kapczuk K; Division of Gynecology, Department of Perinatology and Gynecology, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
Kędzia W; Division of Gynecology, Department of Perinatology and Gynecology, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 25; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
46, XX Disorders of Sex Development/*pathology
Amenorrhea/*genetics
Amenorrhea/*pathology
Cervix Uteri/*abnormalities
Congenital Abnormalities/*pathology
Mullerian Ducts/*abnormalities
Vagina/*abnormalities
17-Hydroxysteroid Dehydrogenases/deficiency ; 17-Hydroxysteroid Dehydrogenases/genetics ; Androgen-Insensitivity Syndrome/genetics ; Androgen-Insensitivity Syndrome/pathology ; Cervix Uteri/embryology ; Cholestenone 5 alpha-Reductase/deficiency ; Cholestenone 5 alpha-Reductase/genetics ; Congenital Abnormalities/diagnosis ; Disorder of Sex Development, 46,XY/genetics ; Disorder of Sex Development, 46,XY/pathology ; Female ; Humans ; Male ; Mullerian Ducts/pathology ; Testis/abnormalities ; Testis/pathology ; Vagina/embryology
SCR Disease Name:
Leydig Cell Hypoplasia; Mullerian aplasia
Czasopismo naukowe
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Tytuł:
Ageratum conyzoides L. inhibits 5-alpha-reductase gene expression in human prostate cells and reduces symptoms of benign prostatic hypertrophy in otherwise healthy men in a double blind randomized placebo controlled clinical study.
Autorzy:
Detering M; School of Chemistry, Queensland University of Technology, Brisbane, QLD, Australia.
Steels E; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Koyyalamudi SR; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, NSW, Australia.; Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, The University of Sydney, Sydney, NSW, Australia.
Allifranchini E; ABICH S.r.l, Biological and chemical analysis, via 42 Martiri 213/B 28924 Verbania, Italy.
Bocchietto E; ABICH S.r.l, Biological and chemical analysis, via 42 Martiri 213/B 28924 Verbania, Italy.
Vitetta L; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.; Medlab Clinical, Sydney, NSW, Australia.
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Źródło:
BioFactors (Oxford, England) [Biofactors] 2017 Nov; Vol. 43 (6), pp. 789-800. Date of Electronic Publication: 2017 Oct 19.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
5-alpha Reductase Inhibitors/*pharmacology
Ageratum/*chemistry
Anti-Inflammatory Agents/*pharmacology
Cholestenone 5 alpha-Reductase/*genetics
Prostate/*drug effects
Prostatic Hyperplasia/*drug therapy
5-alpha Reductase Inhibitors/isolation & purification ; Adult ; Aged ; Anti-Inflammatory Agents/isolation & purification ; Biomarkers/blood ; Blood Glucose/metabolism ; Cell Line ; Cholestenone 5 alpha-Reductase/metabolism ; Dehydroepiandrosterone Sulfate/blood ; Dihydrotestosterone/blood ; Double-Blind Method ; Estradiol/blood ; Humans ; Hydrocortisone/blood ; Kallikreins/blood ; Male ; Middle Aged ; Plant Extracts/chemistry ; Prostate/metabolism ; Prostate/pathology ; Prostate-Specific Antigen/blood ; Prostatic Hyperplasia/blood ; Prostatic Hyperplasia/genetics ; Prostatic Hyperplasia/pathology ; Sex Hormone-Binding Globulin/genetics ; Sex Hormone-Binding Globulin/metabolism ; Testosterone/blood ; Treatment Outcome ; Urination/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores.
Autorzy:
Opoku-Acheampong AB; Department of Food, Nutrition, Dietetics and Health, Kansas State University, Manhattan, KS, United States of America.
Henningson JN; College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States of America.
Beck AP; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States of America.
Lindshield BL; Department of Food, Nutrition, Dietetics and Health, Kansas State University, Manhattan, KS, United States of America.
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Źródło:
PloS one [PLoS One] 2017 May 11; Vol. 12 (5), pp. e0175874. Date of Electronic Publication: 2017 May 11 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Cholestenone 5 alpha-Reductase/*genetics
Prostatic Intraepithelial Neoplasia/*genetics
Prostatic Neoplasms/*genetics
Receptors, Androgen/*genetics
Animals ; Cholestenone 5 alpha-Reductase/biosynthesis ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice ; Prostatic Hyperplasia/genetics ; Prostatic Hyperplasia/pathology ; Prostatic Intraepithelial Neoplasia/pathology ; Prostatic Neoplasms/pathology ; RNA, Messenger/biosynthesis ; Receptors, Tumor Necrosis Factor, Member 25/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inhibitory Activities of Dimeric Ellagitannins Isolated from C ornus alba on Benign Prostatic Hypertrophy.
Autorzy:
Park DH; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Park KH; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Yin J; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Kim MJ; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Yoon SE; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Lee SH; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Heo JH; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Chung HJ; Department of Urology, College of Medicine, Chung-Ang University, Seoul 06974, Korea.
Kim JW; Department of Urology, College of Medicine, Chung-Ang University, Seoul 06974, Korea.
Kim KM; Life Science Research Institute, NOVAREX.CO., Ltd., Cheongju 363885, Korea.
Lee MW; Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 06; Vol. 26 (11). Date of Electronic Publication: 2021 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cholestenone 5 alpha-Reductase/*metabolism
Cornus/*chemistry
Hydrolyzable Tannins/*pharmacology
Interleukins/*metabolism
Prostatic Hyperplasia/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Hydrolyzable Tannins/chemistry ; Hydrolyzable Tannins/isolation & purification ; Male ; Molecular Structure ; Prostatic Hyperplasia/drug therapy ; Rats ; Th1 Cells
Czasopismo naukowe
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Wyświetlanie 1-20 z 73

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