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Wyszukujesz frazę ""Cholesterol, LDL"" wg kryterium: Temat


Tytuł :
The Role of Structure and Biophysical Properties in the Pleiotropic Effects of Statins.
Autorzy :
Murphy C; School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Deplazes E; School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Cranfield CG; School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Garcia A; School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 19; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anticholesteremic Agents/*therapeutic use
Cell Membrane/*drug effects
Cholesterol, LDL/*antagonists & inhibitors
Hydroxymethylglutaryl CoA Reductases/*chemistry
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Hypercholesterolemia/*drug therapy
Anticholesteremic Agents/chemical synthesis ; Anticholesteremic Agents/metabolism ; Biological Transport ; Biotransformation ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Cholesterol, LDL/biosynthesis ; Cholesterol, LDL/blood ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Humans ; Hydrophobic and Hydrophilic Interactions ; Hydroxymethylglutaryl CoA Reductases/genetics ; Hydroxymethylglutaryl CoA Reductases/metabolism ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/chemical synthesis ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/metabolism ; Hypercholesterolemia/blood ; Hypercholesterolemia/genetics ; Hypercholesterolemia/pathology ; Lipid Bilayers/chemistry ; Lipid Bilayers/metabolism ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Models, Molecular ; Protein Binding ; Protein Structure, Secondary ; Thermodynamics
Czasopismo naukowe
Tytuł :
Estimation of the LDL subclasses in ischemic stroke as a risk factor in a Chinese population.
Autorzy :
Duan R; Department of Neurology, Hebei General Hospital, Shijiazhuang, 050000, Hebei, China. .
Xue W; Department of Neurology, the First People's Hospital of Pingdingshan, Henan, 467000, Pingdingshan, China.
Wang K; Department of Neurosurgery, the Affiliated Hospital of Chengde Medical University, Chengde, 067000, Hebei, China.
Yin N; Department of Neurology, Hebei General Hospital, Shijiazhuang, 050000, Hebei, China.
Hao H; Department of Neurology, Hebei General Hospital, Shijiazhuang, 050000, Hebei, China.
Chu H; Department of Neurology, Hebei General Hospital, Shijiazhuang, 050000, Hebei, China.
Wang L; Department of Medicine, Shanghai Zhangjiang institute of Medical innovation, Biotecan Pharmaceuticals co., ltd., Shanghai, 201204, China.
Meng P; Department of Medicine, Shanghai Zhangjiang institute of Medical innovation, Biotecan Pharmaceuticals co., ltd., Shanghai, 201204, China. .
Diao L; Department of Medicine, Shanghai Zhangjiang institute of Medical innovation, Biotecan Pharmaceuticals co., ltd., Shanghai, 201204, China. .
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Źródło :
BMC neurology [BMC Neurol] 2020 Nov 13; Vol. 20 (1), pp. 414. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Cholesterol, LDL*/blood
Cholesterol, LDL*/classification
Ischemic Stroke*/blood
Ischemic Stroke*/epidemiology
Case-Control Studies ; China/epidemiology ; Humans ; Risk Factors
Czasopismo naukowe
Tytuł :
Analysis of the acrolein-modified sites of apolipoprotein B-100 in LDL.
Autorzy :
Kobayashi M; Departments of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Watanabe K; Division of Pharmacy, Chiba University Hospital, Chiba, Japan.
Suzuki T; RIKEN Center Sustainable Resource Science, Yokohama, Japan.
Dohmae N; RIKEN Center Sustainable Resource Science, Yokohama, Japan.
Fujiyoshi M; Departments of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Uchida M; Departments of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan; Division of Pharmacy, Chiba University Hospital, Chiba, Japan.
Suzuki T; Division of Pharmacy, Chiba University Hospital, Chiba, Japan.
Igarashi K; Departments of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan; Amine Pharma Research Institute, Innovation Plaza at Chiba University, Chiba, Japan.
Ishii I; Departments of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan; Division of Pharmacy, Chiba University Hospital, Chiba, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Jan; Vol. 1866 (1), pp. 158809. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acrolein/*chemistry
Apolipoprotein B-100/*chemistry
Cholesterol, LDL/*chemistry
Serine-Arginine Splicing Factors/*chemistry
Amino Acid Sequence ; Apolipoprotein B-100/genetics ; Apolipoprotein B-100/metabolism ; Binding Sites ; Cholesterol, LDL/metabolism ; Gene Expression ; Humans ; Models, Molecular ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Serine-Arginine Splicing Factors/genetics ; Serine-Arginine Splicing Factors/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels.
Autorzy :
Pirim D; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Molecular Biology and Genetics, Faculty of Arts & Science, Bursa Uludag University, Gorukle, Bursa, Turkey.
Bunker CH; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Hokanson JE; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado, United States of America.
Hamman RF; Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado, United States of America.
Demirci FY; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Kamboh MI; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Dec 16; Vol. 15 (12), pp. e0243919. Date of Electronic Publication: 2020 Dec 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cholesterol, HDL/*blood
Cholesterol, LDL/*blood
Lipase/*genetics
African Americans ; Alleles ; Binding Sites/genetics ; Cholesterol/blood ; Cholesterol/genetics ; Cholesterol Ester Transfer Proteins/blood ; Cholesterol Ester Transfer Proteins/genetics ; Cholesterol, HDL/genetics ; Cholesterol, LDL/genetics ; European Continental Ancestry Group ; Female ; Genotype ; Humans ; Introns/genetics ; Lipase/ultrastructure ; Lipid Metabolism/genetics ; Lipids/blood ; Lipids/genetics ; Male ; Polymorphism, Single Nucleotide ; Protein Binding/genetics ; Protein Conformation ; RNA, Circular/blood ; RNA, Circular/genetics ; RNA, Long Noncoding/genetics ; Triglycerides/blood ; Triglycerides/genetics
Czasopismo naukowe
Tytuł :
Effect of Pharmacogenetic Testing for Statin Myopathy Risk vs Usual Care on Blood Cholesterol: A Randomized Clinical Trial.
Autorzy :
Vassy JL; VA Boston Healthcare System, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Ariadne Labs, Boston, Massachusetts.
Gaziano JM; VA Boston Healthcare System, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Green RC; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Ariadne Labs, Boston, Massachusetts.
Ferguson RE; VA Boston Healthcare System, Boston, Massachusetts.; Department of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Advani S; VA Boston Healthcare System, Boston, Massachusetts.
Miller SJ; VA Boston Healthcare System, Boston, Massachusetts.
Chun S; Massachusetts College of Pharmacy and Health Sciences, Boston.
Hage AK; Massachusetts College of Pharmacy and Health Sciences, Boston.
Seo SJ; Massachusetts College of Pharmacy and Health Sciences, Boston.
Majahalme N; VA Boston Healthcare System, Boston, Massachusetts.
MacMullen L; VA Boston Healthcare System, Boston, Massachusetts.
Zimolzak AJ; VA Boston Healthcare System, Boston, Massachusetts.; Baylor College of Medicine, Houston, Texas.; Michael E. DeBakey VA Medical Center, Houston, Texas.
Brunette CA; VA Boston Healthcare System, Boston, Massachusetts.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Dec 01; Vol. 3 (12), pp. e2027092. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cholesterol, LDL/*drug effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology
Liver-Specific Organic Anion Transporter 1/*drug effects
Liver-Specific Organic Anion Transporter 1/*genetics
Medication Adherence/*statistics & numerical data
Adult ; Aged ; Boston ; Cholesterol/blood ; Cholesterol, LDL/blood ; Female ; Humans ; Male ; Middle Aged ; Muscular Diseases ; Pharmacogenetics/methods ; Risk Factors ; United States ; United States Department of Veterans Affairs
Czasopismo naukowe
Tytuł :
Association of small, dense LDL-cholesterol concentration and lipoprotein particle characteristics with coronary heart disease: A systematic review and meta-analysis.
Autorzy :
Liou L; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Kaptoge S; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
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Źródło :
PloS one [PLoS One] 2020 Nov 09; Vol. 15 (11), pp. e0241993. Date of Electronic Publication: 2020 Nov 09 (Print Publication: 2020).
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Cholesterol, LDL/*blood
Coronary Disease/*blood
Lipoproteins/*blood
Atherosclerosis/blood ; Atherosclerosis/complications ; Biomarkers/analysis ; Biomarkers/blood ; Cholesterol, LDL/analysis ; Coronary Disease/etiology ; Humans ; Lipoproteins/analysis ; Particle Size ; Risk Factors
Czasopismo naukowe
Tytuł :
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids.
Autorzy :
van der Graaf A; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.
Claringbould A; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.; Oncode institute, Office Jaarbeurs Innovation Mile (JIM), Jaarbeursplein 6, 3521, Utrecht, AL, The Netherlands.
Rimbert A; University of Groningen, University Medical Centre Groningen, Department of Pediatrics, Section Molecular Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.; Université de Nantes, CNRS, INSERM, l'institut du thorax, F-44000, Nantes, France.
Westra HJ; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.; Oncode institute, Office Jaarbeurs Innovation Mile (JIM), Jaarbeursplein 6, 3521, Utrecht, AL, The Netherlands.
Li Y; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.; Department of Computational Biology for Individualised Infection Medicine, Centre for Individualised Infection Medicine (CiiM) & TWINCORE, joint ventures between the Helmholtz-Centre for Infection Research (HZI) and the Hannover Medical School (MHH), 30625, Hannover, Germany.; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525, Nijmegen, HP, The Netherlands.
Wijmenga C; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands.
Sanna S; University of Groningen, University Medical Centre Groningen, Department of Genetics, Antonius Deusinglaan 1, 9713, Groningen, AV, The Netherlands. .; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Cittadella Universitaria di Monserrato, 09042, Monserrato, Italy. .
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Corporate Authors :
BIOS Consortium
Źródło :
Nature communications [Nat Commun] 2020 Oct 01; Vol. 11 (1), pp. 4930. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Genetic Predisposition to Disease*
Models, Genetic*
Quantitative Trait Loci*
Cholesterol, LDL/*blood
Adaptor Proteins, Vesicular Transport/genetics ; Adaptor Proteins, Vesicular Transport/metabolism ; Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Cholesterol, LDL/metabolism ; Computer Simulation ; Datasets as Topic ; Genetic Pleiotropy ; Humans ; Linkage Disequilibrium ; Lipid Metabolism/genetics ; Mendelian Randomization Analysis ; Metabolic Networks and Pathways/genetics ; Multifactorial Inheritance ; Nectins/genetics ; Nectins/metabolism ; Netherlands ; Proteomics ; RNA-Seq
Czasopismo naukowe
Tytuł :
Low-density lipoprotein cholesterol and all-cause mortality: findings from the China health and retirement longitudinal study.
Autorzy :
Zhou L; Liyang Center for Disease Control and Prevention, Liyang, Jiangsu, China.
Wu Y; State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
Yu S; Medical College of Soochow University, Suzhou, Jiangsu, China.
Shen Y; Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu, China .
Ke C; Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu, China .
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Źródło :
BMJ open [BMJ Open] 2020 Aug 16; Vol. 10 (8), pp. e036976. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol, LDL*
Hand Strength*
Mortality*
Retirement*
Aged ; China/epidemiology ; Cholesterol, HDL ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Prospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Management of Blood Cholesterol in Diabetes.
Autorzy :
Goldberg RB; Division of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine, Miami, FL .
Stone NJ; Feinberg School of Medicine, Northwestern University, Chicago, IL.
Grundy SM; University of Texas Southwestern Medical Center, Dallas, TX.
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Źródło :
Diabetes care [Diabetes Care] 2020 Aug; Vol. 43 (8), pp. 1673-1678.
Typ publikacji :
Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiology/*standards
Cardiovascular Diseases/*prevention & control
Cholesterol, LDL/*blood
Diabetes Mellitus/*drug therapy
Diabetic Angiopathies/*prevention & control
Adult ; Age Factors ; Aged ; Aged, 80 and over ; American Heart Association ; Atherosclerosis/blood ; Atherosclerosis/prevention & control ; Cardiology/organization & administration ; Cardiovascular Diseases/blood ; Cholesterol, LDL/drug effects ; Diabetes Mellitus/blood ; Diabetes Mellitus/epidemiology ; Diabetic Angiopathies/blood ; Geriatrics/organization & administration ; Geriatrics/standards ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Hypercholesterolemia/blood ; Hypercholesterolemia/drug therapy ; Hypercholesterolemia/epidemiology ; Hypertriglyceridemia/blood ; Hypertriglyceridemia/drug therapy ; Hypertriglyceridemia/epidemiology ; Middle Aged ; Nursing/organization & administration ; Nursing/standards ; Pharmacists/organization & administration ; Pharmacists/standards ; Primary Prevention/organization & administration ; Primary Prevention/standards ; Risk Assessment ; Risk Factors ; Societies, Medical/standards ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Investigating the effect of antiretroviral switch to tenofovir alafenamide on lipid profiles in people living with HIV.
Autorzy :
Lacey A; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.
Savinelli S; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.; Department of Infectious Diseases, St Vincent's University Hospital, Dublin, Ireland.
Barco EA; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.
Macken A; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.
Cotter AG; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.; Department of Infectious Diseases, Mater Misericordiae University Hospital.; Department of Infectious Diseases, St Vincent's University Hospital, Dublin, Ireland.
Sheehan G; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.; Department of Infectious Diseases, Mater Misericordiae University Hospital.
Lambert JS; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.; Department of Infectious Diseases, Mater Misericordiae University Hospital.
Muldoon E; Department of Infectious Diseases, Mater Misericordiae University Hospital.
Feeney E; Department of Infectious Diseases, St Vincent's University Hospital, Dublin, Ireland.
Mallon PW; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.; Department of Infectious Diseases, Mater Misericordiae University Hospital.; Department of Infectious Diseases, St Vincent's University Hospital, Dublin, Ireland.
Tinago W; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin.
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Corporate Authors :
UCD ID Cohort Study
Źródło :
AIDS (London, England) [AIDS] 2020 Jul 01; Vol. 34 (8), pp. 1161-1170.
Typ publikacji :
Journal Article
MeSH Terms :
Adenine/*analogs & derivatives
Anti-HIV Agents/*therapeutic use
Cholesterol, LDL/*drug effects
HIV Infections/*drug therapy
Lipid Metabolism/*drug effects
Lipids/*blood
Tenofovir/*therapeutic use
Adenine/adverse effects ; Adenine/therapeutic use ; Adult ; Anti-HIV Agents/adverse effects ; Cholesterol/blood ; Cholesterol, LDL/blood ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Tenofovir/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage.
Autorzy :
Falcone GJ; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Kirsch E; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Acosta JN; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Noche RB; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Leasure A; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Marini S; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.
Chung J; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.
Selim M; Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Meschia JF; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.
Brown DL; Stroke Program, Department of Neurology, University of Michigan Health System, Ann Arbor, MI, USA.
Worrall BB; Department of Neurology and Public Health Sciences, University of Virginia Health System, Charlottesville, VA, USA.
Tirschwell DL; Stroke Center, Harborview Medical Center, University of Washington, Seattle, WA, USA.
Jagiella JM; Department of Neurology, Jagiellonian University Medical College, Kraków, Poland.
Schmidt H; Institute of Molecular Biology and Medical Biochemistry, Medical University Graz, Graz, Austria.
Jimenez-Conde J; Neurovascular Research Unit, Department of Neurology, Institut Municipal d'Investigacio' Medica-Hospital del Mar, Universitat Autonoma de Barcelona, Barcelona, Spain.; Program in Inflammation and Cardiovascular Disorders, Institut Municipal d'Investigacio' Medica-Hospital del Mar, Universitat Autonoma de Barcelona, Barcelona, Spain.
Fernandez-Cadenas I; Neurovascular Research Laboratory and Neurovascular Unit, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.
Lindgren A; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden.
Slowik A; Department of Neurology, Jagiellonian University Medical College, Kraków, Poland.
Gill D; Department of Epidemiology and Biostatistics and Department of Stroke Medicine, Imperial College London, London, UK.
Holmes M; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.
Phuah CL; Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Petersen NH; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Matouk Md CN; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Gunel M; Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Sansing L; Division of Vascular Neurology and Stroke, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Bennett D; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.
Chen Z; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.
Sun LL; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Clarke R; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Walters RG; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.
Gill TM; Department of Internal Medicine, Geriatric Medicine, Yale School of Medicine, New Haven, CT, USA.
Biffi A; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Division of Behavioral Neurology, Department of Neurology, MGH, Boston, MA, USA.; Division of Psychiatry, Department of Psychiatry, MGH, Boston, MA, USA.
Kathiresan S; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Cardiovascular Disease Prevention Center, MGH, Boston, MA, USA.
Langefeld CD; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Woo D; Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Rosand J; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Neurology, MGH, Boston, MA, USA.; Henry and Allison McCance Center for Brain Health, MGH, Boston, MA, USA.
Sheth KN; Division of Neurocritical Care & Emergency Neurology, Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Anderson CD; Center for Genomic Medicine, Massachusetts General Hospital (MGH), Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Neurology, MGH, Boston, MA, USA.; Henry and Allison McCance Center for Brain Health, MGH, Boston, MA, USA.
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Corporate Authors :
International Stroke Genetics Consortium
Źródło :
Annals of neurology [Ann Neurol] 2020 Jul; Vol. 88 (1), pp. 56-66. Date of Electronic Publication: 2020 May 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Cerebral Hemorrhage/*blood
Cerebral Hemorrhage/*genetics
Cholesterol, LDL/*blood
Aged ; Aged, 80 and over ; Cholesterol, HDL/blood ; Cholesterol, HDL/genetics ; Cholesterol, LDL/genetics ; Female ; Genome-Wide Association Study ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Triglycerides/blood ; Triglycerides/genetics
Czasopismo naukowe
Tytuł :
Prognostic value of lipid levels in short-term outcome after TAVI.
Autorzy :
Yelgeç NS; Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, 34668, Üsküdar-Istanbul, Turkey. .
Emre A; Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, 34668, Üsküdar-Istanbul, Turkey.
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Transliterated Title :
Prognostischer Wert der Lipidspiegel beim Kurzzeitverlauf nach TAVI.
Źródło :
Herz [Herz] 2020 Jun; Vol. 45 (4), pp. 382-388. Date of Electronic Publication: 2019 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Aortic Valve Stenosis*
Cholesterol, HDL*
Cholesterol, LDL*
Heart Valve Prosthesis Implantation*
Humans ; Prognosis ; Retrospective Studies ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cognition After Lowering LDL-Cholesterol With Evolocumab.
Autorzy :
Gencer B; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Mach F; Cardiology Division, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland.
Guo J; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Im K; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Ruzza A; AMGEN, Thousand Oaks, California.
Wang H; AMGEN, Thousand Oaks, California.
Kurtz CE; AMGEN, Thousand Oaks, California.
Pedersen TR; Department of Preventive Cardiology, Oslo University Hospital, Aker and Medical Faculty, University of Oslo, Oslo, Norway.
Keech AC; Sydney Medical School, NHMRC Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia.
Ott BR; Rhode Island Hospital, Brown University, Providence, Rhode Island.
Sabatine MS; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Giugliano RP; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: .
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Corporate Authors :
FOURIER Investigators
Źródło :
Journal of the American College of Cardiology [J Am Coll Cardiol] 2020 May 12; Vol. 75 (18), pp. 2283-2293.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Humanized/*administration & dosage
Anticholesteremic Agents/*administration & dosage
Atherosclerosis/*blood
Cardiovascular Diseases/*blood
Cholesterol, LDL/*blood
Cognition/*drug effects
Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal, Humanized/adverse effects ; Anticholesteremic Agents/adverse effects ; Atherosclerosis/drug therapy ; Atherosclerosis/psychology ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/psychology ; Cholesterol, LDL/antagonists & inhibitors ; Cognition/physiology ; Cognitive Dysfunction/blood ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/psychology ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Metabolic effects of PCSK9 inhibition with Evolocumab in subjects with elevated Lp(a).
Autorzy :
Zhang X; Department of Experimental Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. .; Human and Animal Physiology, Wageningen University, De Elst 1, 6708 WD, Wageningen, The Netherlands. .
Stiekema LCA; Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Stroes ESG; Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Groen AK; Department of Experimental Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
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Źródło :
Lipids in health and disease [Lipids Health Dis] 2020 May 11; Vol. 19 (1), pp. 91. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial
MeSH Terms :
Antibodies, Monoclonal, Humanized/*therapeutic use
Cholesterol, LDL/*antagonists & inhibitors
Hyperlipidemias/*drug therapy
Hypolipidemic Agents/*therapeutic use
Lipoprotein(a)/*antagonists & inhibitors
Proprotein Convertase 9/*antagonists & inhibitors
Aged ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Cholesterol, VLDL/antagonists & inhibitors ; Cholesterol, VLDL/blood ; Female ; Gene Expression ; Humans ; Hyperlipidemias/blood ; Hyperlipidemias/diagnosis ; Hyperlipidemias/genetics ; Lipid Metabolism/drug effects ; Lipoprotein(a)/blood ; Magnetic Resonance Spectroscopy ; Male ; Metabolome ; Middle Aged ; Multivariate Analysis ; Proprotein Convertase 9/blood ; Proprotein Convertase 9/genetics ; Triglycerides/antagonists & inhibitors ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Low-density lipoprotein cholesterol lowering treatment: the current approach.
Autorzy :
Crismaru I; Emergency Institute for Cardiovascular Diseases 'C.C. Iliescu', Bucharest, Romania.
Pantea Stoian A; Department of Diabetes, Nutrition and Metabolic Diseases, Faculty of General Medicine, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
Bratu OG; 'Carol Davila' University of Medicine and Pharmacy, 'Carol Davila' University Emergency Central Emergency Military Hospital, Academy of Romanian Scientists, Bucharest, Romania.
Gaman MA; 'Carol Davila' University of Medicine and Pharmacy, 'I. Cantacuzino' Clinical Hospital, Bucharest, Romania.
Stanescu AMA; 'Carol Davila' University of Medicine and Pharmacy, 'I. Cantacuzino' Clinical Hospital, Bucharest, Romania.
Bacalbasa N; 'Carol Davila' University of Medicine and Pharmacy, 'I. Cantacuzino' Clinical Hospital, Bucharest, Romania.
Diaconu CC; Department of Internal Medicine, 'Carol Davila' University of Medicine and Pharmacy, Clinical Emergency Hospital of Bucharest, 8 Eroii Sanitari Blvd, 050474, Bucharest, Romania. .
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Źródło :
Lipids in health and disease [Lipids Health Dis] 2020 May 06; Vol. 19 (1), pp. 85. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anticholesteremic Agents/*therapeutic use
Atherosclerosis/*prevention & control
Cholesterol, LDL/*antagonists & inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Hypercholesterolemia/*drug therapy
Antibodies, Monoclonal, Humanized/therapeutic use ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Benzimidazoles/therapeutic use ; Bile Acids and Salts/antagonists & inhibitors ; Bile Acids and Salts/metabolism ; Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cholesterol, LDL/metabolism ; Dicarboxylic Acids/therapeutic use ; Europe ; Ezetimibe/therapeutic use ; Fatty Acids/therapeutic use ; Gene Expression ; Guidelines as Topic ; Humans ; Hypercholesterolemia/genetics ; Hypercholesterolemia/metabolism ; Hypercholesterolemia/pathology ; Proprotein Convertase 9/antagonists & inhibitors ; Proprotein Convertase 9/genetics ; Proprotein Convertase 9/metabolism ; RNA, Small Interfering/therapeutic use
Czasopismo naukowe
Tytuł :
Benefit of Targeting a LDL (Low-Density Lipoprotein) Cholesterol <70 mg/dL During 5 Years After Ischemic Stroke.
Autorzy :
Amarenco P; From the APHP, Department of Neurology and Stroke center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, University of Paris, France (P.A., J.L., H.C.).
Kim JS; Asan Medical Center, Seoul, South Korea (J.S.K.).
Labreuche J; From the APHP, Department of Neurology and Stroke center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, University of Paris, France (P.A., J.L., H.C.).
Charles H; From the APHP, Department of Neurology and Stroke center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, University of Paris, France (P.A., J.L., H.C.).
Giroud M; Department of Neurology, University Hospital of Dijon, University of Burgundy, France (M.G.).
Lee BC; Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea (B.-C.L.).
Mahagne MH; Stroke Unit, Pasteur Hospital, Nice, France (M.-H.M.).
Nighoghossian N; Hospices Civils de Lyon, Department of Neurology and Stroke Center, Lyon University, France (N.N.).
Gabriel Steg P; APHP, Department of cardiology, INSERM LVTS-U1148, DHU FIRE, University of Paris, Hôpital Bichat, France (P.G.S.).
Vicaut É; NHLI Imperial College, ICMS Royal Brompton Hospital London, United Kingdom (P.G.S.).; APHP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal hospital, France (É.V.).
Bruckert E; APHP, Department of Endocrinology, Pitié-Salpêtrière hospital, Sorbonne University, Paris, France (E.B.).
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Corporate Authors :
Treat Stroke to Target Investigators
Źródło :
Stroke [Stroke] 2020 Apr; Vol. 51 (4), pp. 1231-1239. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*blood
Brain Ischemia/*drug therapy
Cholesterol, LDL/*blood
Drug Delivery Systems/*trends
Stroke/*blood
Stroke/*drug therapy
Aged ; Anticholesteremic Agents/administration & dosage ; Brain Ischemia/diagnostic imaging ; Cholesterol, LDL/antagonists & inhibitors ; Ezetimibe/administration & dosage ; Female ; Humans ; Male ; Middle Aged ; Stroke/diagnostic imaging ; Time Factors
Czasopismo naukowe
Tytuł :
Association of Non-LDL Indices with Recurrent Stroke Risk while on Lipid-Modifying Therapy.
Autorzy :
Park JH; Department of Neurology, Myongji Hospital, Hanyang University College of Medicine.
Ovbiagele B; Department of Neurology, University of California.
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Źródło :
Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2020 Feb 01; Vol. 27 (2), pp. 144-154. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Cholesterol, HDL*/blood
Cholesterol, HDL*/metabolism
Cholesterol, LDL*/blood
Cholesterol, LDL*/metabolism
Dyslipidemias*/blood
Dyslipidemias*/drug therapy
Dyslipidemias*/metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacokinetics
Secondary Prevention*/methods
Secondary Prevention*/statistics & numerical data
Stroke*/blood
Stroke*/diagnosis
Stroke*/prevention & control
Triglycerides*/blood
Triglycerides*/metabolism
Aged ; Correlation of Data ; Drug Monitoring/methods ; Female ; Humans ; Lipid Metabolism/drug effects ; Lipid Regulating Agents/administration & dosage ; Lipid Regulating Agents/pharmacokinetics ; Male ; Middle Aged ; Prognosis ; Risk Assessment
Czasopismo naukowe
Tytuł :
Influence of Serum Cholinesterase Levels on Patients Suspected of Having Stable Coronary Artery Disease.
Autorzy :
Mito T; Cardiology, Hakujyuji Hospital, Japan.; Munakata Suikokai General Hospital, Japan.
Takemoto M; Munakata Suikokai General Hospital, Japan.; Cardiovascular Center, Steel Memorial Yawata Hospital, Japan.
Antoku Y; Munakata Suikokai General Hospital, Japan.; Cardiovascular Center, Steel Memorial Yawata Hospital, Japan.
Tanaka A; Munakata Suikokai General Hospital, Japan.
Matsuo A; Munakata Suikokai General Hospital, Japan.
Hida S; Munakata Suikokai General Hospital, Japan.
Yoshitake K; Munakata Suikokai General Hospital, Japan.
Kosuga KI; Munakata Suikokai General Hospital, Japan.
Miura SI; Department of Cardiovascular Medicine, Fukuoka University Hospital, Japan.
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Źródło :
Internal medicine (Tokyo, Japan) [Intern Med] 2021 Apr 15; Vol. 60 (8), pp. 1145-1150. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Coronary Artery Disease*/diagnostic imaging
Coronary Artery Disease*/epidemiology
Myocardial Ischemia*/diagnosis
Myocardial Ischemia*/epidemiology
Cholesterol, LDL ; Cholinesterases ; Coronary Angiography ; Humans ; Risk Factors
Czasopismo naukowe
Tytuł :
Relation of First and Total Recurrent Atherosclerotic Cardiovascular Disease Events to Increased Lipoprotein(a) Levels Among Statin Treated Adults With Cardiovascular Disease.
Autorzy :
Wong ND; Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California; Department of Epidemiology, University of California Los Angeles, Los Angeles, California. Electronic address: .
Zhao Y; Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California; Department of Epidemiology, University of California Los Angeles, Los Angeles, California.
Sung J; Global Outcomes Research, Novartis Inc.
Browne A; Global Outcomes Research, Novartis Inc.
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Źródło :
The American journal of cardiology [Am J Cardiol] 2021 Apr 15; Vol. 145, pp. 12-17. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Lipoprotein(a)/*blood
Acute Coronary Syndrome/epidemiology ; Aged ; Atherosclerosis/blood ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/drug therapy ; Cholesterol, LDL/blood ; Coronary Disease/mortality ; Female ; Hospitalization/statistics & numerical data ; Humans ; Ischemic Stroke/epidemiology ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Myocardial Revascularization/statistics & numerical data ; Prognosis ; Proportional Hazards Models
Czasopismo naukowe

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