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Podgląd okładki
Tytuł :
Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade.
Autorzy :
Winek K; The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Lobentanzer S; Department of Pharmacology, College of Pharmacy, Goethe University, 60438 Frankfurt am Main, Germany.
Nadorp B; The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; The Grass Center for Bioengineering, Benin School of Computer Science and Engineering, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Dubnov S; The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Dames C; The Institute for Medical Immunology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Jagdmann S; The Institute for Medical Immunology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Moshitzky G; The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Hotter B; NeuroCure Clinical Research, Center for Stroke Research Berlin, Department of Neurology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Meisel C; The Institute for Medical Immunology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Greenberg DS; The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Shifman S; Department of Genetics, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
Klein J; Department of Pharmacology, College of Pharmacy, Goethe University, 60438 Frankfurt am Main, Germany.
Shenhar-Tsarfaty S; Department of Internal Medicine 'C,' 'D,' and 'E,' Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, 6997801 Tel Aviv, Israel.
Meisel A; NeuroCure Clinical Research, Center for Stroke Research Berlin, Department of Neurology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Soreq H; The Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel; .; The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 22; Vol. 117 (51), pp. 32606-32616. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Ischemic Stroke/*genetics
Ischemic Stroke/*immunology
MicroRNAs/*immunology
Non-Neuronal Cholinergic System/*immunology
RNA, Transfer/*immunology
Aged ; Animals ; Case-Control Studies ; Female ; Humans ; Inflammation/etiology ; Inflammation/genetics ; Inflammation/immunology ; Ischemic Stroke/physiopathology ; Lipopolysaccharide Receptors/metabolism ; Lipopolysaccharides/pharmacology ; Male ; Mice ; MicroRNAs/blood ; MicroRNAs/genetics ; Middle Aged ; Monocytes/physiology ; Non-Neuronal Cholinergic System/genetics ; Prospective Studies ; RAW 264.7 Cells ; RNA, Transfer/blood ; RNA, Transfer/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways.
Autorzy :
Johnson K; Department of Cellular and Molecular Physiology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
Yin J; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
In JG; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
Kulkarni S; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
Pasricha P; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
Tse CM; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
Donowitz M; Department of Cellular and Molecular Physiology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.; Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Aug 01; Vol. 319 (2), pp. C321-C330. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscarinic Agonists/*pharmacology
Non-Neuronal Cholinergic System/*genetics
Receptors, Muscarinic/*genetics
Receptors, Nicotinic/*genetics
Acetylcholine/pharmacology ; Animals ; Anions/metabolism ; Atropine/pharmacology ; Cholinergic Agonists/pharmacology ; Enterocytes/drug effects ; Enterocytes/metabolism ; Hexamethonium/pharmacology ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Intestines/drug effects ; Mice ; Non-Neuronal Cholinergic System/drug effects ; Receptors, Muscarinic/metabolism ; Receptors, Nicotinic/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins.
Autorzy :
Lagoumintzis G; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece.
Chasapis CT; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece.
Alexandris N; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece.
Kouretas D; Department of Biochemistry and Biotechnology, Faculty of Animal Physiology -Toxicology, University of Thessaly, Larissa, Greece.
Tzartos S; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece; Tzartos NeuroDiagnostics, 3, Eslin Street, Athens, 115 23, Greece.
Eliopoulos E; Department of Biotechnology, Laboratory of Genetics, Agricultural University of Athens, Iera Odos 75, 11855, Athens, Greece. Electronic address: .
Farsalinos K; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece. Electronic address: .
Poulas K; Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Panepistimiopolis, 26500, Rio-Patras, Greece. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Mar; Vol. 149, pp. 112009. Date of Electronic Publication: 2021 Jan 24.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes*
COVID-19/*virology
Nicotine/*pharmacology
SARS Virus/*chemistry
SARS-CoV-2/*chemistry
Spike Glycoprotein, Coronavirus/*chemistry
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Amino Acid Sequence ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Viral/chemistry ; Antibodies, Viral/therapeutic use ; Binding Sites, Antibody ; COVID-19/metabolism ; COVID-19/prevention & control ; Humans ; Models, Molecular ; Nicotinic Agonists/chemistry ; Nicotinic Agonists/therapeutic use ; Non-Neuronal Cholinergic System ; Pandemics ; Protective Factors ; Protein Conformation ; Sequence Homology ; Signal Transduction ; Smokers ; Smoking ; Snake Venoms/chemistry
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The Role of the Non-neuronal Cholinergic System in Inflammation and Degradation Processes in Osteoarthritis.
Autorzy :
Courties A; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Do A; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Leite S; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Legris M; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Sudre L; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Pigenet A; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Petit J; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Nourissat G; 2INSERM UMR 938, Centre de Recherche Saint-Antoine, Clinique Maussins, Groupe Ramsay Générale de Santé, Paris, France.
Cambon-Binder A; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Maskos U; Institut Pasteur, Neurobiologie Intégrative des Systèmes Cholinergiques, CNRS UMR 3571, Paris, France.
Berenbaum F; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
Sellam J; Sorbonne Université, INSERM UMR 938, Centre de Recherche Saint-Antoine, Hôpital Saint-Antoine, AP-HP, Paris, France.
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Źródło :
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2020 Dec; Vol. 72 (12), pp. 2072-2082. Date of Electronic Publication: 2020 Oct 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrocytes/*metabolism
Inflammation/*metabolism
Non-Neuronal Cholinergic System/*physiology
Osteoarthritis/*metabolism
Receptors, Nicotinic/*metabolism
Aged ; Animals ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Female ; Humans ; Male ; Mice ; Middle Aged ; alpha7 Nicotinic Acetylcholine Receptor/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Robustness of the non-neuronal cholinergic system in rat large intestine against luminal challenges.
Autorzy :
Bader S; Institute for Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, Giessen, Germany.
Gerbig S; Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Giessen, Germany.
Spengler B; Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Giessen, Germany.
Schwiertz A; MVZ Institute of Microecology, Herborn, Germany.
Breves G; Department of Physiology, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Diener M; Institute for Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, Giessen, Germany. .; Institut für Veterinär-Physiologie und -Biochemie, Justus-Liebig-Universität Gießen, Frankfurter Str. 100, 35392, Giessen, Germany. .
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Źródło :
Pflugers Archiv : European journal of physiology [Pflugers Arch] 2019 Apr; Vol. 471 (4), pp. 605-618. Date of Electronic Publication: 2018 Dec 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine/*metabolism
Colon/*metabolism
Intestinal Mucosa/*metabolism
Non-Neuronal Cholinergic System/*physiology
Animals ; Choline/analogs & derivatives ; Choline/metabolism ; Colon/drug effects ; Diet ; Epithelium/drug effects ; Epithelium/metabolism ; Fatty Acids, Volatile/metabolism ; Intestinal Mucosa/drug effects ; Male ; Non-Neuronal Cholinergic System/drug effects ; Propionates/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The non-neuronal cholinergic system in the heart: A comprehensive review.
Autorzy :
Saw EL; Department of Physiology-HeartOtago, School of Biomedical Sciences, University of Otago, New Zealand.
Kakinuma Y; Department of Physiology (Bioregulatory Science), Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Fronius M; Department of Physiology-HeartOtago, School of Biomedical Sciences, University of Otago, New Zealand. Electronic address: .
Katare R; Department of Physiology-HeartOtago, School of Biomedical Sciences, University of Otago, New Zealand. Electronic address: .
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Źródło :
Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2018 Dec; Vol. 125, pp. 129-139. Date of Electronic Publication: 2018 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Myocytes, Cardiac/*metabolism
Non-Neuronal Cholinergic System/*physiology
Acetylcholine/metabolism ; Animals ; Cardiovascular Diseases/metabolism ; Humans ; Non-Neuronal Cholinergic System/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
S-Nitroso-N-Pivaloyl-D-Penicillamine, a novel non-neuronal ACh system activator, modulates cardiac diastolic function to increase cardiac performance under pathophysiological conditions.
Autorzy :
Oikawa S; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Kai Y; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Mano A; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Nakamura S; Department of Chemistry, Nippon Medical School, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-0023, Japan.
Kakinuma Y; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2020 Jul; Vol. 84, pp. 106459. Date of Electronic Publication: 2020 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Cardiovascular Diseases/*physiopathology
Heart/*drug effects
Nitric Oxide Donors/*pharmacology
Non-Neuronal Cholinergic System/*physiology
Penicillamine/*pharmacology
Ventricular Function, Left/*drug effects
Animals ; Blood Pressure/drug effects ; Injections, Intraperitoneal ; Injections, Intravenous ; Mice ; Mice, Inbred Strains ; Nitric Oxide Donors/administration & dosage ; Nitric Oxide Donors/therapeutic use ; Penicillamine/administration & dosage ; Penicillamine/analogs & derivatives ; Penicillamine/therapeutic use
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Circular RNA expression profile of Alzheimer's disease and its clinical significance as biomarkers for the disease risk and progression.
Autorzy :
Li Y; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Fan H; The First Affiliated Hospital of Henan University of Science and Technology, School of Clinical Medicine, Henan University of Science and Technology, Luoyang, China.
Sun J; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Ni M; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Clinical Pharmacy, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Zhang L; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Chen C; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Hong X; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Fang F; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Zhang W; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
Ma P; Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China; Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China; Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China. Electronic address: .
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Źródło :
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2020 Jun; Vol. 123, pp. 105747. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*cerebrospinal fluid
Amyloid beta-Peptides/*cerebrospinal fluid
Peptide Fragments/*cerebrospinal fluid
RNA, Circular/*cerebrospinal fluid
Signal Transduction/*genetics
tau Proteins/*cerebrospinal fluid
Aged ; Alzheimer Disease/genetics ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Biomarkers/cerebrospinal fluid ; Disease Progression ; Down-Regulation ; Female ; Gene Ontology ; Humans ; Killer Cells, Natural/immunology ; Logistic Models ; Male ; MicroRNAs/cerebrospinal fluid ; MicroRNAs/genetics ; Microarray Analysis ; Middle Aged ; Nerve Growth Factors/cerebrospinal fluid ; Nerve Growth Factors/genetics ; Non-Neuronal Cholinergic System/genetics ; Peptide Fragments/genetics ; Peptide Fragments/metabolism ; RNA, Circular/genetics ; ROC Curve ; Real-Time Polymerase Chain Reaction ; Up-Regulation ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis.
Autorzy :
Shabani Z; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Neuroscience, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahmoudi J; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farajdokht F; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Sadigh-Eteghad S; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Persian Medicine, Faculty of Persian Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; East-Azerbaijan Comprehensive Stroke Program, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
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Źródło :
Archives of medical research [Arch Med Res] 2020 May; Vol. 51 (4), pp. 287-296. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cholinergic Agents/*therapeutic use
Neurogenesis/*physiology
Nicotine/*metabolism
Non-Neuronal Cholinergic System/*physiology
Humans ; Signal Transduction
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Segmental differences in the non-neuronal cholinergic system in rat caecum.
Autorzy :
Bader S; Institute for Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, Frankfurter Str. 100, Giessen, Germany.
Diener M; Institute for Veterinary Physiology and Biochemistry, Justus Liebig University Giessen, Frankfurter Str. 100, Giessen, Germany. .
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Źródło :
Pflugers Archiv : European journal of physiology [Pflugers Arch] 2018 Apr; Vol. 470 (4), pp. 669-679. Date of Electronic Publication: 2018 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcholine/*metabolism
Cecum/*metabolism
Neurons/*metabolism
Non-Neuronal Cholinergic System/*physiology
Animals ; Anions/metabolism ; Atropine/pharmacology ; Carbachol/pharmacology ; Cecum/drug effects ; Chlorides/metabolism ; Cholinergic Agonists/pharmacology ; Colon/drug effects ; Colon/metabolism ; Conotoxins/pharmacology ; Epithelium/drug effects ; Epithelium/metabolism ; Fatty Acids, Volatile/metabolism ; Female ; Hexamethonium/pharmacology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Male ; Neurons/drug effects ; Neurotransmitter Agents/metabolism ; Non-Neuronal Cholinergic System/drug effects ; Propionates/pharmacology ; Rats ; Rats, Wistar ; Tetrodotoxin/pharmacology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Anxiety and depression in adolescents with asthma and in their parents. Is an increased basal cholinergic tone a possible further reason to explain the negative impact on asthma control?
Autorzy :
Liccardi G; Postgraduate School of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata'. .
Calzetta L; Postgraduate School of Respiratory Medicine, Department of Experimental Medicine; Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome 'Tor Vergata'. .
Milanese M; Division of Pulmonology, S. Corona Hospital, Pietra Ligure. .
Bilò MB; Allergy Unit, Department of Internal Medicine, University Hospital Ospedali Riuniti, Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona. .
Liccardi MV; Psychologist, Naples. .
Matera MG; Department of Experimental Medicine, Second University of Naples. .
Rogliani P; Postgraduate School of Respiratory Medicine, Department of Experimental Medicine; Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome 'Tor Vergata'. .
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Źródło :
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace [Monaldi Arch Chest Dis] 2020 Apr 08; Vol. 90 (1). Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Letter
MeSH Terms :
Anxiety/*physiopathology
Asthma/*physiopathology
Asthma/*psychology
Depression/*physiopathology
Parents/*psychology
Stress, Psychological/*physiopathology
Adolescent ; Adult ; Anxiety/psychology ; Bronchial Hyperreactivity/physiopathology ; Bronchial Hyperreactivity/psychology ; Cholinergic Neurons/physiology ; Depression/psychology ; Humans ; Non-Neuronal Cholinergic System/physiology ; Parent-Child Relations ; Stress, Psychological/psychology ; Vagus Nerve/physiopathology
Opinia redakcyjna
Szczegóły
Podgląd okładki
Tytuł :
A historic perspective on the current progress in elucidation of the biologic significance of non-neuronal acetylcholine.
Autorzy :
Grando SA; Department of Dermatology, University of California, Irvine, CA 92697, USA.
Kawashima K; Department of Molecular Pharmacology, Kitasato University School of Pharmacy, Tokyo 108-8641, Japan.
Wessler I; Institute of Pathology, University Medical Center, Johannes Gutenberg-University, Mainz D-55101, Germany.
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2020 Apr; Vol. 81, pp. 106289. Date of Electronic Publication: 2020 Feb 26.
Typ publikacji :
Congress; Editorial
MeSH Terms :
Acetylcholine/*metabolism
Immune System Diseases/*metabolism
Neoplasms/*metabolism
Neurons/*physiology
Non-Neuronal Cholinergic System/*physiology
Animals ; Homeostasis ; Humans ; Interdisciplinary Communication ; Neuronal Plasticity
Opinia redakcyjna
Szczegóły
Podgląd okładki
Tytuł :
[The role of central cholinergic system in epilepsy].
Autorzy :
Wang Y; College of Pharmaceutial Science, Zhejiang University, Hangzhou 310058, China.
Wang Y; College of Pharmaceutial Science, Zhejiang University, Hangzhou 310058, China.
Chen Z; College of Pharmaceutial Science, Zhejiang University, Hangzhou 310058, China. .
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Źródło :
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences [Zhejiang Da Xue Xue Bao Yi Xue Ban] 2017 Jan 25; Vol. 46 (1), pp. 15-21.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinergic Neurons/*chemistry
Cholinergic Neurons/*pathology
Cholinergic Neurons/*physiology
Epilepsy/*genetics
Epilepsy/*pathology
Epilepsy/*physiopathology
Non-Neuronal Cholinergic System/*physiology
Acetylcholine/physiology ; Basal Forebrain/pathology ; Brain Chemistry/genetics ; Brain Chemistry/physiology ; Cholinergic Neurons/classification ; Epilepsy, Frontal Lobe/genetics ; GABAergic Neurons/physiology ; Hippocampus/pathology ; Humans ; Mutation/genetics ; Mutation/physiology ; Neurons ; Non-Neuronal Cholinergic System/genetics ; Receptors, Muscarinic/genetics ; Receptors, Muscarinic/physiology ; Receptors, Nicotinic/genetics ; Receptors, Nicotinic/physiology ; Synaptic Transmission/genetics ; Synaptic Transmission/physiology
SCR Disease Name :
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Addition of lafutidine can improve disease activity and lead to better quality of life in refractory cholinergic urticaria unresponsive to histamine H1 antagonists.
Autorzy :
Hatakeyama M; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Fukunaga A; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. Electronic address: .
Washio K; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Ogura K; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Yamada Y; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Horikawa T; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Nishigori C; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan; Department of Dermatology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273, Japan; Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
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Źródło :
Journal of dermatological science [J Dermatol Sci] 2016 May; Vol. 82 (2), pp. 137-9. Date of Electronic Publication: 2016 Feb 08.
Typ publikacji :
Clinical Trial; Letter
MeSH Terms :
Non-Neuronal Cholinergic System*
Acetamides/*therapeutic use
Histamine H1 Antagonists/*therapeutic use
Histamine H2 Antagonists/*therapeutic use
Piperidines/*therapeutic use
Pyridines/*therapeutic use
Urticaria/*drug therapy
Adolescent ; Adult ; Drug Therapy, Combination ; Female ; Humans ; Male ; Quality of Life ; Urticaria/etiology ; Young Adult
Raport
Szczegóły
Podgląd okładki
Tytuł :
Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of epilepsy.
Autorzy :
Soares JI; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; Instituto de Biologia Molecular e Celular da Universidade do Porto, Porto, Portugal; Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal; Programa Doutoral em Neurociências, Universidade do Porto, Porto, Portugal. Electronic address: .
Da Costa C; Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
Ferreira MH; Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
Andrade PA; University of Eastern Finland, A.I. Virtanen Institute for Molecular Sciences, Kuopio, Finland.
Maia GH; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; Instituto de Biologia Molecular e Celular da Universidade do Porto, Porto, Portugal; Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
Lukoyanov NV; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; Instituto de Biologia Molecular e Celular da Universidade do Porto, Porto, Portugal; Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
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Źródło :
Brain research [Brain Res] 2019 Aug 15; Vol. 1717, pp. 235-246. Date of Electronic Publication: 2019 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholinergic Neurons/*metabolism
Cholinergic Neurons/*physiology
Seizures/*physiopathology
Animals ; Cholinergic Agents/pharmacology ; Disease Susceptibility/metabolism ; Epilepsy/chemically induced ; Epilepsy/physiopathology ; Hippocampus/metabolism ; Kainic Acid/pharmacology ; Male ; Neurons/metabolism ; Non-Neuronal Cholinergic System/physiology ; Rats ; Rats, Wistar ; Saporins/pharmacology ; Seizures/chemically induced ; Seizures/metabolism ; Status Epilepticus/chemically induced ; Temporal Lobe/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Molecular mechanisms involved in the prevention and reversal of ketamine-induced schizophrenia-like behavior by rutin: the role of glutamic acid decarboxylase isoform-67, cholinergic, Nox-2-oxidative stress pathways in mice
Autorzy :
Oshodi, Tolulope Olabode
Ben-Azu, BennethAff2, Aff3
Ishola, Ismail O.
Ajayi, Abayomi Mayowa
Emokpae, Osagie
Umukoro, Solomon
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Źródło :
Molecular Biology Reports: An International Journal on Molecular and Cellular Biology. :1-16
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na-ATPase in an Alzheimer’s disease model
Autorzy :
Pinz, Mikaela Peglow
Vogt, Ane Gabriela
da Costa Rodrigues, Karline
dos Reis, Angélica Schiavom
Duarte, Luis Fernando Barbosa
Fronza, Mariana Gallio
Domingues, William Borges
Blodorn, Eduardo Bierhaus
Alves, Diego
Campos, Vinicius Farias
Savegnago, Lucielli
Wilhelm, Ethel Antunes
Luchese, Cristiane
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Źródło :
Metabolic Brain Disease. :1-18
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
A Novel Nitric Oxide Donor, S-Nitroso-NPivaloyl-D-Penicillamine, Activates a Non-Neuronal Cardiac Cholinergic System to Synthesize Acetylcholine and Augments Cardiac Function.
Autorzy :
Oikawa S; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, Toyko, Japan.
Kai Y; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, Toyko, Japan.
Mano A; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, Toyko, Japan.
Nakamura S; Department of Chemistry, Nippon Medical School, Tokyo, Japan.
Kakinuma Y; Department of Bioregulatory Science (Physiology), Nippon Medical School Graduate School of Medicine, Toyko, Japan, .
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Źródło :
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2019; Vol. 52 (4), pp. 922-934.
Typ publikacji :
Journal Article
MeSH Terms :
Nitric Oxide Donors*/chemistry
Nitric Oxide Donors*/pharmacology
Acetylcholine/*biosynthesis
Cardiac Output/*drug effects
Cyclic GMP/*metabolism
Myocytes, Cardiac/*metabolism
Non-Neuronal Cholinergic System/*drug effects
Animals ; HEK293 Cells ; Humans ; Male ; Mice ; Nitric Oxide/biosynthesis
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Angioedema frequently occurs in cholinergic urticaria.
Autorzy :
Mellerowicz EJ; Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Asady A; Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Maurer M; Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address: .
Altrichter S; Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
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Źródło :
The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2019 Apr; Vol. 7 (4), pp. 1355-1357.e1. Date of Electronic Publication: 2018 Oct 25.
Typ publikacji :
Letter
MeSH Terms :
Angioedema/*diagnosis
Skin/*pathology
Urticaria/*diagnosis
Adolescent ; Adult ; Exercise ; Female ; Humans ; Male ; Non-Neuronal Cholinergic System ; Retrospective Studies ; Young Adult
Opinia redakcyjna
Szczegóły
Wyświetlanie 1-20 z 4467

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