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Wyszukujesz frazę ""Cholinesterase Inhibitors"" wg kryterium: Temat


Tytuł:
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
Autorzy:
Makhaeva GF; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Kovaleva NV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Rudakova EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Boltneva NP; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Lushchekina SV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia.
Astakhova TY; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia.
Timokhina EN; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia.
Serkov IV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Proshin AN; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Soldatova YV; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Poletaeva DA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Faingold II; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Mumyatova VA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Terentiev AA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Radchenko EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Palyulin VA; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Bachurin SO; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Richardson RJ; Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.; Center of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.; Michigan Institute for Computational Discovery and Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 09; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Alzheimer Disease*/drug therapy
Animals ; Mice ; Antioxidants/pharmacology ; Butyrylcholinesterase ; Acetylcholinesterase ; Pharmacophore
Czasopismo naukowe
Tytuł:
Can Activation of Acetylcholinesterase by β-Amyloid Peptide Decrease the Effectiveness of Cholinesterase Inhibitors?
Autorzy:
Zueva IV; Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center 'Kazan Scientific Center of the Russian Academy of Sciences', Arbuzov Str., 8, 420088 Kazan, Russia.
Vasilieva EA; Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center 'Kazan Scientific Center of the Russian Academy of Sciences', Arbuzov Str., 8, 420088 Kazan, Russia.
Gaynanova GA; Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center 'Kazan Scientific Center of the Russian Academy of Sciences', Arbuzov Str., 8, 420088 Kazan, Russia.
Moiseenko AV; Faculty of Biology, Lomonosov Moscow State University, Leninskie Gory, 1-12, 119991 Moscow, Russia.
Burtseva AD; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect, 33/2, 119071 Moscow, Russia.; Landau Phystech School of Physics and Research, Moscow Institute of Physics and Technology, Institutsky Lane, 9, Dolgoprudny, 141700 Moscow, Russia.
Boyko KM; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect, 33/2, 119071 Moscow, Russia.
Zakharova LY; Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center 'Kazan Scientific Center of the Russian Academy of Sciences', Arbuzov Str., 8, 420088 Kazan, Russia.
Petrov KA; Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center 'Kazan Scientific Center of the Russian Academy of Sciences', Arbuzov Str., 8, 420088 Kazan, Russia.; Institute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 16; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Cholinesterase Inhibitors*/therapeutic use
Alzheimer Disease*/drug therapy
Alzheimer Disease*/pathology
Humans ; Acetylcholinesterase ; Amyloid beta-Peptides ; Butyrylcholinesterase
Czasopismo naukowe
Tytuł:
Anticholinesterase and Antityrosinase Secondary Metabolites from the Fungus Xylobolus subpileatus .
Autorzy:
Felegyi K; Department of Pharmacognosy, Semmelweis University, 1085 Budapest, Hungary.
Garádi Z; Department of Pharmacognosy, Semmelweis University, 1085 Budapest, Hungary.; Directorate of Drug Substance Development, Egis Pharmaceuticals Plc., 1475 Budapest, Hungary.
Studzińska-Sroka E; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3 Str., 60-806 Poznan, Poland.
Papp V; Department of Botany, Hungarian University of Agriculture and Life Sciences, 1118 Budapest, Hungary.
Boldizsár I; Department of Pharmacognosy, Semmelweis University, 1085 Budapest, Hungary.; Department of Plant Anatomy, Institute of Biology, Eötvös Loránd University, 1117 Budapest, Hungary.
Dancsó A; Directorate of Drug Substance Development, Egis Pharmaceuticals Plc., 1475 Budapest, Hungary.
Béni S; Department of Pharmacognosy, Semmelweis University, 1085 Budapest, Hungary.; Department of Analytical Chemistry, Institute of Chemistry, Eötvös Loránd University, 1117 Budapest, Hungary.
Zalewski P; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3 Str., 60-806 Poznan, Poland.
Ványolós A; Department of Pharmacognosy, Semmelweis University, 1085 Budapest, Hungary.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 30; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Basidiomycota*
Acetylcholinesterase ; Butyrylcholinesterase ; Chloroform ; Methanol ; Plant Extracts
SCR Organism:
Xylobolus subpileatus
Czasopismo naukowe
Tytuł:
Screening of Acetylcholinesterase Inhibitors by Capillary Electrophoresis with Oriented-Immobilized Enzyme Microreactors Based on Gold Nanoparticles.
Autorzy:
Zhang J; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.; Institute of Medicine, Xi'an Medical University, Xi'an 710021, China.
Li Y; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.
Chen L; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.
Zheng Z; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.; Institute of Medicine, Xi'an Medical University, Xi'an 710021, China.
Liu C; School of Pharmacy, Xi'an Medical University, Xi'an 710021, China.; Institute of Medicine, Xi'an Medical University, Xi'an 710021, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 24; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Metal Nanoparticles*
Enzymes, Immobilized ; Acetylcholinesterase ; Gold ; Electrophoresis, Capillary ; Concanavalin A
Czasopismo naukowe
Tytuł:
Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability.
Autorzy:
Žunec S; Division of Toxicology, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000 Zagreb, Croatia.
Vadlja D; Armed Forces of the Republic of Croatia, Trg Kralja Petra Krešimira IV br. 1, 10000 Zagreb, Croatia.
Ramić A; Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Zandona A; Division of Toxicology, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000 Zagreb, Croatia.
Maraković N; Division of Toxicology, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000 Zagreb, Croatia.
Brekalo I; Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Primožič I; Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Katalinić M; Division of Toxicology, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000 Zagreb, Croatia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Butyrylcholinesterase*
Humans ; Acetylcholinesterase ; Bromides ; Cell Survival ; Acetylcholine ; Pain ; Quinuclidines/pharmacology
Czasopismo naukowe
Tytuł:
Synthesis and Cholinesterase Inhibitory Activity of Selected Indole-Based Compounds.
Autorzy:
Grošelj U; a. University of Ljubljana, Faculty of Chemistry and Chemical Technology, Večna pot 113, SI-1000 Ljubljana. .
Gršič M; .
Meden A; .
Knez D; .
Jukič M; .
Svete J; .
Gobec S; .
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Źródło:
Acta chimica Slovenica [Acta Chim Slov] 2023 Nov 02; Vol. 70 (4), pp. 545-559. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Butyrylcholinesterase*/chemistry
Cholinesterase Inhibitors*/pharmacology
Humans ; Indoles/pharmacology ; Indoles/chemistry ; Acetylcholinesterase/metabolism ; Structure-Activity Relationship ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
The anti-Alzheimer potential of novel spiroindolin-1,2-diazepine derivatives as targeted cholinesterase inhibitors with modified substituents.
Autorzy:
Pourtaher H; Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran.
Hasaninejad A; Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran. .
Zare S; Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Tanideh N; Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Iraji A; Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 24; Vol. 13 (1), pp. 11952. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholinesterase Inhibitors*
Azepines*
Humans ; Kinetics ; Molecular Docking Simulation ; Acetylthiocholine ; Pain
Czasopismo naukowe
Tytuł:
In Vitro and In Silico Evaluation of Anticholinesterase and Antidiabetic Effects of Furanolabdanes and Other Constituents from Graptophyllum pictum (Linn.) Griffith.
Autorzy:
Metiefeng NT; Department of Organic Chemistry, Faculty of Science, The University of Yaounde I, Yaounde 812, Cameroon.
Tamfu AN; Department of Chemical Engineering, School of Chemical Engineering and Mineral Industries, University of Ngaoundere, Ngaoundere 454, Cameroon.; Department of Medical Services and Techniques, Koycegiz Vocational School of Health Services, Mugla Sitki Kocman University, Mugla 48800, Turkey.; Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, 'Dunarea de Jos' University of Galati, 47 Domneasca Str., 800008 Galati, Romania.
Fotsing Tagatsing M; Department of Organic Chemistry, Faculty of Science, The University of Yaounde I, Yaounde 812, Cameroon.
Tabopda TK; Department of Organic Chemistry, Faculty of Science, The University of Yaounde I, Yaounde 812, Cameroon.
Kucukaydin S; Department of Medical Services and Techniques, Koycegiz Vocational School of Health Services, Mugla Sitki Kocman University, Mugla 48800, Turkey.
Noah Mbane M; Department of Organic Chemistry, Faculty of Science, The University of Yaounde I, Yaounde 812, Cameroon.
de Theodore Atchade A; Department of Organic Chemistry, Faculty of Science, The University of Yaounde I, Yaounde 812, Cameroon.
Talla E; Department of Chemical Engineering, School of Chemical Engineering and Mineral Industries, University of Ngaoundere, Ngaoundere 454, Cameroon.
Henoumont C; Laboratory of NMR and Molecular Imaging, Department of General, Organic and Biomedical Chemistry, University of Mons, B-7000 Mons, Belgium.
Laurent S; Laboratory of NMR and Molecular Imaging, Department of General, Organic and Biomedical Chemistry, University of Mons, B-7000 Mons, Belgium.
Anouar EH; Department of Chemistry, College of Sciences and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Dinica RM; Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, 'Dunarea de Jos' University of Galati, 47 Domneasca Str., 800008 Galati, Romania.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 16; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/pharmacology
Cholinesterase Inhibitors*/chemistry
Diterpenes*
Hypoglycemic Agents/chemistry ; Butyrylcholinesterase/metabolism ; Acetylcholinesterase/metabolism ; alpha-Glucosidases/metabolism ; Molecular Docking Simulation ; Plant Extracts/chemistry ; Antioxidants/chemistry ; alpha-Amylases
Czasopismo naukowe
Tytuł:
Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis.
Autorzy:
Liu HM; Department of Anesthesiology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Sichuan, Chengdu 610041, China.
Yu H; Department of Anesthesiology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Sichuan, Chengdu 610041, China.
Zuo YD; Department of Anesthesiology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Sichuan, Chengdu 610041, China.
Liang P; Department of Anesthesiology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Sichuan, Chengdu 610041, China. liangpeng_.; Day Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China. liangpeng_.
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Źródło:
BMC anesthesiology [BMC Anesthesiol] 2023 Apr 20; Vol. 23 (1), pp. 130. Date of Electronic Publication: 2023 Apr 20.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/therapeutic use
Cholinesterase Inhibitors*/pharmacology
Neostigmine*/pharmacology
Neuromuscular Blockade*
Pulmonary Atelectasis*/epidemiology
Pulmonary Atelectasis*/prevention & control
Sugammadex*
Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control ; Neuromuscular Blocking Agents
Czasopismo naukowe
Tytuł:
In Silico and In Vitro Methods in the Characterization of Beta-Carotene as Pharmaceutical Material via Acetylcholine Esterase Inhibitory Actions.
Autorzy:
Muthuraman A; Pharmacology Unit, Faculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
Ramesh M; Department of Pharmaceutical Analysis, Omega College of Pharmacy, Hyderabad 501301, India.
Mustaffa F; Pharmacology Unit, Faculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
Nadeem A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Nishat S; Comprehensive Cancer Center, Wexner Medical Centre, Ohio State University, Columbus, OH 43210, USA.
Paramakrishnan N; Department of Pharmacognosy, JSS College of Pharmacy, Mysore, JSS Academy of Higher Education and Research, Mysore 570015, India.
Lim KG; Pharmacology Unit, Faculty of Pharmacy, AIMST University, Bedong 08100, Malaysia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 26; Vol. 28 (11). Date of Electronic Publication: 2023 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/chemistry
Alzheimer Disease*/drug therapy
Animals ; Acetylcholine ; beta Carotene ; Molecular Docking Simulation ; Zebrafish/metabolism ; Acetylcholinesterase/metabolism ; Pharmaceutical Preparations
Czasopismo naukowe
Tytuł:
Unravelling Novel Phytochemicals and Anticholinesterase Activity in Irish Cladonia portentosa .
Autorzy:
Nagar S; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 02, D02 PN40 Dublin, Ireland.
Pigott M; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 02, D02 PN40 Dublin, Ireland.
Kukula-Koch W; Department of Pharmacognosy, Medical University of Lublin, 1 Chodzki Street, 20-093 Lublin, Poland.
Sheridan H; NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin 02, D02 PN40 Dublin, Ireland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 17; Vol. 28 (10). Date of Electronic Publication: 2023 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/chemistry
Acetylcholinesterase*
Hexanes ; Methanol ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Phytochemicals/pharmacology ; Antioxidants/chemistry
SCR Organism:
Cladonia portentosa
Czasopismo naukowe
Tytuł:
Anti-dementia drugs: a descriptive study of the prescription pattern in Italy.
Autorzy:
Ippoliti I; National Centre for Drug Research and Evaluation, Italian National Institute of Health, Via Giano Della Bella 34, 00162, Rome, Italy.
Ancidoni A; National Centre for Disease Prevention and Health Promotion, Italian National Institute of Health, Via Giano Della Bella 34, 00162, Rome, Italy. .; Department of Public Health and Infectious Diseases, Sapienza University, Piazzale Aldo Moro, 5, 00185, Rome, Italy. .
Da Cas R; National Centre for Drug Research and Evaluation, Italian National Institute of Health, Via Giano Della Bella 34, 00162, Rome, Italy.
Pierantozzi A; HTA & Pharmaceutical Economy Division, Italian Medicines Agency, Via del Tritone, 181, 00187, Rome, Italy.
Vanacore N; National Centre for Disease Prevention and Health Promotion, Italian National Institute of Health, Via Giano Della Bella 34, 00162, Rome, Italy.
Trotta F; HTA & Pharmaceutical Economy Division, Italian Medicines Agency, Via del Tritone, 181, 00187, Rome, Italy.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2023 May; Vol. 44 (5), pp. 1587-1595. Date of Electronic Publication: 2023 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterase Inhibitors*/therapeutic use
Alzheimer Disease*/drug therapy
Alzheimer Disease*/epidemiology
Humans ; Memantine/therapeutic use ; Acetylcholinesterase/therapeutic use ; Italy/epidemiology
Czasopismo naukowe
Tytuł:
Computational Approaches to Evaluate the Acetylcholinesterase Binding Interaction with Taxifolin for the Management of Alzheimer's Disease.
Autorzy:
Ahmad V; Health Information Technology Department, The Applied College, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Alotibi I; Health Information Technology Department, The Applied College, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Alghamdi AA; Health Information Technology Department, The Applied College, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pharmacovigilance and Medication Safety Unit, Centre of Research Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Ahmad A; Health Information Technology Department, The Applied College, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pharmacovigilance and Medication Safety Unit, Centre of Research Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Jamal QMS; Department of Health Informatics, College of Public Health and Health Informatics, Qassim University, Al Bukayriyah 52741, Saudi Arabia.
Srivastava S; Department of Health Informatics, College of Public Health and Health Informatics, Qassim University, Al Bukayriyah 52741, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 31; Vol. 29 (3). Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Acetylcholinesterase*/metabolism
Alzheimer Disease*/drug therapy
Quercetin/*analogs & derivatives
Animals ; Butyrylcholinesterase/chemistry ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Cholinesterase Inhibitors/chemistry ; Molecular Docking Simulation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Potential of Tryptamine Derivatives as Multi-Target Directed Ligands for Alzheimer's Disease: AChE, MAO-B, and COX-2 as Molecular Targets.
Autorzy:
Asghar S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.
Mushtaq N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan.
Ahmed A; Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi 75510, Pakistan.
Anwar L; Department of Pharmacology, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.
Munawar R; Department of Pharmaceutical Chemistry, Dow College of Pharmacy, Dow University of Health Sciences, Karachi 74200, Pakistan.
Akhtar S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hamdard University, Karachi 74600, Pakistan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 19; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Monoamine Oxidase*/metabolism
Alzheimer Disease*/metabolism
Humans ; Monoamine Oxidase Inhibitors/chemistry ; Cyclooxygenase 2/metabolism ; Molecular Docking Simulation ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship ; Tryptamines/pharmacology ; Acetylcholinesterase/metabolism ; Ligands
Czasopismo naukowe
Tytuł:
Investigation, scaffold hopping of novel donepezil-based compounds as anti-Alzhiemer's agents: synthesis, in-silico and pharmacological evaluations.
Autorzy:
Gupta M; Department of Pharmacy, Banasthali Vidyapith Newai, Banasthali, Rajasthan, India.
Pant S; Department of Pharmacy, Banasthali Vidyapith Newai, Banasthali, Rajasthan, India.
Rana P; Department of Medicinal Chemistry, National Institute for Pharmaceutical Education and Research (NIPER) Balangar, Hyderabad, India.
Kumar A; Department of Medical Affairs, Curie Sciences Pvt. Ltd., Samastipur, Bihar, 848125, India.
Prasun C; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Nair MS; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Paliwal S; Department of Pharmacy, Banasthali Vidyapith Newai, Banasthali, Rajasthan, India.
Nain S; Department of Pharmacy, Banasthali Vidyapith Newai, Banasthali, Rajasthan, India. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 19; Vol. 14 (1), pp. 1687. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Quinolines*
Pyridines*
Sulfonamides*
Animals ; Donepezil/pharmacology ; Acetylcholinesterase/metabolism ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Structure-Activity Relationship ; Quantitative Structure-Activity Relationship ; Pyrrolidinones ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Multi-Target-Directed Cinnamic Acid Hybrids Targeting Alzheimer's Disease.
Autorzy:
Drakontaeidi A; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Pontiki E; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 01; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acetylcholinesterase*
Alzheimer Disease*/drug therapy
Humans ; Butyrylcholinesterase ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Cinnamates/pharmacology ; Cinnamates/therapeutic use
Czasopismo naukowe
Tytuł:
Differences in the treatment needs of patients with dementia with Lewy bodies and their caregivers and differences in their physicians' awareness of those treatment needs according to the clinical department visited by the patients: a subanalysis of an observational survey study.
Autorzy:
Ikeda M; Department of Psychiatry, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita-Shi, Osaka, 565-0871, Japan. .
Toya S; Medical Science, Sumitomo Pharma Co., Ltd., Chuo-Ku, Tokyo, Japan.
Manabe Y; Department of Advanced Clinical Medicine, Division of Dementia and Geriatric Medicine, Kanagawa Dental University School of Dentistry, Yokosuka, Japan.
Yamakage H; Insight Clinical Development Group, 3H Medi Solution Inc., Toshima-Ku, Tokyo, Japan.
Hashimoto M; Department of Psychiatry, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita-Shi, Osaka, 565-0871, Japan.; Department of Neuropsychiatry, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Mar 14; Vol. 16 (1), pp. 59. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Lewy Body Disease*/drug therapy
Lewy Body Disease*/diagnosis
Physicians*
Aged ; Humans ; Caregivers/psychology ; Cholinesterase Inhibitors/therapeutic use ; Cross-Sectional Studies ; Multicenter Studies as Topic ; Observational Studies as Topic
Czasopismo naukowe
Tytuł:
Acetylcholinesterase enzyme among cancer patients a potential diagnostic and prognostic indicator a multicenter case-control study.
Autorzy:
Ahmed GY; Columbia University Hospital, New York, NY, USA.; Faculty of Medicine, and Health Sciences, Managil University for Sciences & Technology, Managil, Sudan.
Osman AA; Independant Scholar, Chesterfield, UK. .
Mukhtar A; Stack Laboratory, Federal Ministry of Health, Khartoum, Sudan.; Radiation and Isotopes Center Khartoum, Federal Ministry of Health, Khartoum, Sudan.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 01; Vol. 14 (1), pp. 5127. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Pesticides*
Breast Neoplasms*
Male ; Humans ; Adult ; Middle Aged ; Acetylcholinesterase ; Prognosis ; Case-Control Studies ; Organophosphorus Compounds ; Cholinesterase Inhibitors
Czasopismo naukowe
Tytuł:
In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected Berberis Species.
Autorzy:
Tuzimski T; Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Petruczynik A; Department of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Kaproń B; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Plech T; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.; Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Makuch-Kocka A; Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.; Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland.
Janiszewska D; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Sugajski M; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Buszewski B; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
Szultka-Młyńska M; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 28; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Berberine*/pharmacology
Berberis*
Melanoma*
Alkaloids*/pharmacology
Antineoplastic Agents*
Humans ; Acetylcholinesterase ; Butyrylcholinesterase ; Cholinesterase Inhibitors/pharmacology ; Molecular Docking Simulation ; Plant Extracts/pharmacology
Czasopismo naukowe

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