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Tytuł:
Photochemical Transformations of Diverse Biologically Active Resveratrol Analogs in Batch and Flow Reactors.
Autorzy:
Mlakić M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10 000 Zagreb, Croatia.
Perinić H; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10 000 Zagreb, Croatia.; Pliva R&D, Teva Pharmaceutical Industries Ltd., Prilaz baruna Filipovića 29, HR-10 000 Zagreb, Croatia.
Vušak V; Pliva R&D, Teva Pharmaceutical Industries Ltd., Prilaz baruna Filipovića 29, HR-10 000 Zagreb, Croatia.
Horváth O; Environmental and Inorganic Photochemistry Research Group, Center for Natural Sciences, Faculty of Engineering, University of Pannonia, P.O. Box 1158, H-8210 Veszprém, Hungary.
Sampedro D; Departamento de Química, Centro de Investigación en Síntesis Química (CISQ), Universidad de La Rioja, 26006 Logroño, Spain.
Losantos R; Departamento de Química, Centro de Investigación en Síntesis Química (CISQ), Universidad de La Rioja, 26006 Logroño, Spain.
Odak I; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice Hrvatske bb, 88000 Mostar, Bosnia and Herzegovina.
Škorić I; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10 000 Zagreb, Croatia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 29; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*
Cholinesterases*
Resveratrol ; Cyclization ; Galantamine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A method for the efficient evaluation of substrate-based cholinesterase imaging probes for Alzheimer's disease.
Autorzy:
Darvesh S; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.; Department of Medicine (Geriatric Medicine & Neurology), Halifax, Nova Scotia, Canada.; Department of Chemistry and Physics, Mount St. Vincent University, Halifax, Nova Scotia, Canada.
Banfield S; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Dufour M; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Forrestall KL; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Maillet H; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Reid GA; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Sands D; Department of Medical Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Pottie IR; Department of Chemistry and Physics, Mount St. Vincent University, Halifax, Nova Scotia, Canada.; Department of Chemistry, Saint Mary's University, Halifax, Nova Scotia, Canada.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2225797. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterases*/metabolism
Alzheimer Disease*/diagnostic imaging
Humans ; Cholinesterase Inhibitors/chemistry ; Brain ; Acetylcholinesterase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antioxidant, LC-MS Analysis, and Cholinesterase Inhibitory Potentials of Phoenix dactylifera Cultivar Khudari: An In Vitro Enzyme Kinetics and In Silico Study.
Autorzy:
Almalki SG; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah 11952, Saudi Arabia.
Alqurashi YE; Department of Biology, College of Science Al-Zulfi, Majmaah University, Al-Majmaah 11952, Saudi Arabia.
Alturaiki W; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah 11952, Saudi Arabia.
Almawash S; Department of Pharmaceutical Sciences, College of Pharmacy, Shaqra University, Shaqra 11961, Saudi Arabia.
Khan A; Oral Medicine and Allied Dental Sciences Department, Faculty of Dentistry, Taif University, Taif 11099, Saudi Arabia.
Ahmad P; IIRC-5 Clinical Biochemistry and Natural Product Research Laboratory, Integral University, Lucknow 226026, India.
Iqbal D; Department of Health Information Management, College of Applied Medical Sciences, Buraydah Private Colleges, Buraydah 51418, Saudi Arabia.
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Źródło:
Biomolecules [Biomolecules] 2023 Sep 30; Vol. 13 (10). Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholinesterases*
Phoeniceae*/chemistry
Phoeniceae*/metabolism
Antioxidants/pharmacology ; Antioxidants/chemistry ; Acetylcholinesterase/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Chromatography, Liquid ; Molecular Docking Simulation ; Ligands ; Tandem Mass Spectrometry ; Phytochemicals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation/Inhibition of Cholinesterases by Excess Substrate: Interpretation of the Phenomenological b Factor in Steady-State Rate Equation.
Autorzy:
Mukhametgalieva AR; Biochemical Neuropharmacology Laboratory, Kazan Federal University, 18 Ul. Kremlevskaya, 420008 Kazan, Russia.
Nemtarev AV; Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, 8 Ul. Arbuzov, 420088 Kazan, Russia.
Sykaev VV; Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, 8 Ul. Arbuzov, 420088 Kazan, Russia.
Pashirova TN; Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, 8 Ul. Arbuzov, 420088 Kazan, Russia.
Masson P; Biochemical Neuropharmacology Laboratory, Kazan Federal University, 18 Ul. Kremlevskaya, 420008 Kazan, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 21; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cholinesterases*
Esters*/chemistry
Humans ; Catalysis ; Acylation ; Kinetics ; Substrate Specificity ; Hydrolysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected Berberis Species.
Autorzy:
Tuzimski, Tomasz (AUTHOR)
Petruczynik, Anna (AUTHOR)
Kaproń, Barbara (AUTHOR)
Plech, Tomasz (AUTHOR)
Makuch-Kocka, Anna (AUTHOR)
Janiszewska, Daria (AUTHOR)
Sugajski, Mateusz (AUTHOR)
Buszewski, Bogusław (AUTHOR)
Szultka-Młyńska, Małgorzata (AUTHOR)
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Źródło:
Molecules. Mar2024, Vol. 29 Issue 5, p1048. 28p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
( S )- N -Benzyl-1-phenyl-3,4-dihydroisoqunoline-2(1 H )-carboxamide Derivatives, Multi-Target Inhibitors of Monoamine Oxidase and Cholinesterase: Design, Synthesis, and Biological Activity.
Autorzy:
Jin QH; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang LP; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang SS; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
Zhuang DN; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zhang CY; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Zheng ZJ; College of Nursing, Zhejiang Pharmaceutical University, Ningbo 315153, China.
Guan LP; Food and Pharmacy College, Zhejiang Ocean University, Zhoushan 316022, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 09; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Monoamine Oxidase*/metabolism
Cholinesterases*/metabolism
Monoamine Oxidase Inhibitors/pharmacology ; Molecular Docking Simulation ; Structure-Activity Relationship ; Cholinesterase Inhibitors/chemistry ; Acetylcholinesterase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A meta-analysis of normal human blood cholinesterase activities determined by a modified electrometric method.
Autorzy:
Garmavy HMS; Department of Pharmacology, College of Pharmacy, University of Duhok, Duhok, Iraq.
Mohammed AA; Department of Pharmacology, College of Pharmacy, University of Duhok, Duhok, Iraq.
Rashid HM; Department of Pharmacology, College of Pharmacy, University of Duhok, Duhok, Iraq.
Mohammad FK; Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, Iraq.
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Źródło:
Journal of medicine and life [J Med Life] 2023 Jan; Vol. 16 (1), pp. 22-34.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Cholinesterases*/blood
Cholinesterases*/metabolism
Adult ; Female ; Humans ; Male ; Publication Bias
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Development of Potential Multi-Target Inhibitors for Human Cholinesterases and Beta-Secretase 1: A Computational Approach.
Autorzy:
Barbosa, Deyse B. (AUTHOR)
do Bomfim, Mayra R. (AUTHOR)
de Oliveira, Tiago A. (AUTHOR)
da Silva, Alisson M. (AUTHOR)
Taranto, Alex G. (AUTHOR)
Cruz, Jorddy N. (AUTHOR)
de Carvalho, Paulo B. (AUTHOR)
Campos, Joaquín M. (AUTHOR)
Santos, Cleydson B. R. (AUTHOR)
Leite, Franco H. A. (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Dec2023, Vol. 16 Issue 12, p1657. 27p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prognostic Value of Serum Cholinesterase Levels for In-Hospital Mortality among Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Autorzy:
Chen Z; Department of Respiratory and Critical Care Medicine, Wuhu Hospital of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Zha L; Department of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu City, Anhui Province, China.
Feng G; Department of Respiratory and Critical Care Medicine, Wuhu Hospital of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
An Q; Department of Respiratory and Critical Care Medicine, Wuhu Hospital of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Shi F; Department of Respiratory and Critical Care Medicine, Wuhu Hospital of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Xu J; Department of Respiratory and Critical Care Medicine, Wuhu Hospital of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Xu Q; cDepartment of Critical Care Medicine, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu City, Anhui Province, China.; Anhui Clinical Medicine Research Center for Critical Illness Respiratory Diseases, Wuhu City, Anhui Province, China.
Xia H; Postgraduate School of Wuhu Hospital of Traditional Chinese Medicine affiliated with Anhui, University of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Zhang M; Postgraduate School of Wuhu Hospital of Traditional Chinese Medicine affiliated with Anhui, University of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
Li L; Postgraduate School of Wuhu Hospital of Traditional Chinese Medicine affiliated with Anhui, University of Traditional Chinese Medicine, Wuhu City, Anhui Province, China.
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Źródło:
COPD [COPD] 2023 Dec; Vol. 20 (1), pp. 178-185. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Pulmonary Disease, Chronic Obstructive*
Humans ; Prognosis ; Hospital Mortality ; Retrospective Studies ; Disease Progression ; Cholinesterases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of Five Drying Methods on Active Compound Contents and Bioactivities of Fresh Flowers from Syringa pubescens Turcz.
Autorzy:
Xu W; College of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Zhang J; College of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Wu Y; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.
Zhang Z; College of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Wang X; College of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang 471023, China.
Ma J; College of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang 471023, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 27; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Antioxidants*/chemistry
Syringa*
Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Monophenol Monooxygenase ; alpha-Glucosidases ; Hydrogen Peroxide ; Anti-Inflammatory Agents/pharmacology ; Flowers ; alpha-Amylases ; Cholinesterases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Standard Treatment Alone versus Standard Treatment Plus Plasmapheresis on the Levels of Serum Pseudocholinesterase and Erythrocyte Acetyl Cholinesterase in Critically Patients with Organophosphate Poisoning: Randomized Controlled, Open-Label, ClinicalTrial.
Autorzy:
Sezgin, Gulten Can
Sipahioglu, Hilal
Gundogan, Kursat
Coskun, Ramazan
Temel, Sahin
Yazici, Cevat
Akdur, Okhan
Sungur, Murat
Guven, Muhammet
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Źródło:
Hitit Medical Journal. Oct2023, Vol. 5 Issue 3, p209-215. 7p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inhibition of Enzymes Involved in Neurodegenerative Disorders and A β 1-40 Aggregation by Citrus limon Peel Polyphenol Extract.
Autorzy:
Arcone R; Dipartimento di Scienze Motorie e del Benessere, Università degli Studi di Napoli 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
D'Errico A; Dipartimento di Scienze Motorie e del Benessere, Università degli Studi di Napoli 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
Nasso R; Dipartimento di Scienze Motorie e del Benessere, Università degli Studi di Napoli 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
Rullo R; ISPAAM, Consiglio Nazionale delle Ricerche, Piazzale Enrico Fermi, 1, 80055 Portici, Italy.
Poli A; ICB, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078 Pozzuoli, Italy.
Di Donato P; ICB, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078 Pozzuoli, Italy.; Dipartimento di Scienze e Tecnologie, Università degli Studi di Napoli 'Parthenope', Centro Direzionale Isola C4, 80143 Napoli, Italy.
Masullo M; Dipartimento di Scienze Motorie e del Benessere, Università degli Studi di Napoli 'Parthenope', Via Medina, 40, 80133 Napoli, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 30; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Parkinson Disease*
Citrus*
Superoxide Dismutase ; Monoamine Oxidase ; Cholinesterases ; Superoxide Dismutase-1 ; Plant Extracts/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Histamine H 3 receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.
Autorzy:
Lopes FB; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo, São Paulo, Brazil.
Aranha CMSQ; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo, São Paulo, Brazil.
Fernandes JPS; Department of Pharmaceutical Sciences, Universidade Federal de São Paulo, São Paulo, Brazil.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 Aug; Vol. 98 (2), pp. 212-225. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Ligands*
Cholinesterases/*chemistry
Receptors, Histamine H3/*chemistry
Binding Sites ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/metabolism ; Cholinesterase Inhibitors/therapeutic use ; Cholinesterases/metabolism ; Cognitive Dysfunction/drug therapy ; Cognitive Dysfunction/pathology ; Drug Design ; Histamine Antagonists/chemistry ; Histamine Antagonists/metabolism ; Histamine Antagonists/therapeutic use ; Humans ; Molecular Docking Simulation ; Receptors, Histamine H3/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.
Autorzy:
Dakhlaoui I; Laboratoire LINC UR 481, Pôle de Chimie Médicinale, Université de Franche-Comté, F-25000 Besançon, France.; Laboratory of Applied Chemistry, Heterocycles, Lipids and Polymers, Faculty of Sciences of Sfax, University of Sfax, B. P 802, Sfax 3000, Tunisia.
Bernard PJ; Laboratoire LINC UR 481, Pôle de Chimie Médicinale, Université de Franche-Comté, F-25000 Besançon, France.
Pietrzak D; Department of Biopharmacy, Medical University of Lublin, ul. W. Chodzki 4a, 20-093 Lublin, Poland.
Simakov A; PEPITE EA4267, Université de Franche-Comté, F-25000 Besançon, France.
Maj M; Department of Biopharmacy, Medical University of Lublin, ul. W. Chodzki 4a, 20-093 Lublin, Poland.
Refouvelet B; Laboratoire LINC UR 481, Pôle de Chimie Médicinale, Université de Franche-Comté, F-25000 Besançon, France.
Béduneau A; PEPITE EA4267, Université de Franche-Comté, F-25000 Besançon, France.
Cornu R; PEPITE EA4267, Université de Franche-Comté, F-25000 Besançon, France.
Jozwiak K; Department of Biopharmacy, Medical University of Lublin, ul. W. Chodzki 4a, 20-093 Lublin, Poland.
Chabchoub F; Laboratory of Applied Chemistry, Heterocycles, Lipids and Polymers, Faculty of Sciences of Sfax, University of Sfax, B. P 802, Sfax 3000, Tunisia.
Iriepa I; Department of Organic Chemistry and Inorganic Chemistry, Universidad de Alcalá, Ctra. Madrid-Barcelona, Km. 33,6, 28871 Alcalá de Henares, Spain.
Martin H; PEPITE EA4267, Université de Franche-Comté, F-25000 Besançon, France.
Marco-Contelles J; Laboratory of Medicinal Chemistry (IQOG, CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Ismaili L; Laboratoire LINC UR 481, Pôle de Chimie Médicinale, Université de Franche-Comté, F-25000 Besançon, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 04; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 04.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Neurodegenerative Diseases*/drug therapy
Dihydropyridines*/pharmacology
Dihydropyridines*/therapeutic use
Humans ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/therapeutic use ; Ligands ; Calcium Channels ; Cholinesterases/metabolism ; Acetylcholinesterase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer's Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties.
Autorzy:
Munir R; School of Chemistry, University of the Punjab, Lahore 54590, Pakistan.; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan.
Zaib S; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
Zia-Ur-Rehman M; Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore 54600, Pakistan.
Hussain N; Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, Al Ain P.O. Box 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi P.O. Box 144534, United Arab Emirates.
Chaudhry F; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan.
Younas MT; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
Zahra FT; Department of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Tajammul Z; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
Javid N; Chemistry Department (C-Block), Forman Christian College, Ferozepur Road, Lahore 54600, Pakistan.
Dera AA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 62529, Saudi Arabia.
Ogaly HA; Chemistry Department, College of Science, King Khalid University, Abha 61421, Saudi Arabia.; Biochemistry and Molecular Biology Department, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Khan I; Department of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 24; Vol. 28 (5). Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Quinolines*/therapeutic use
Humans ; Cholinesterase Inhibitors/chemistry ; Molecular Docking Simulation ; Acetylcholinesterase/metabolism ; Cholinesterases/metabolism ; Structure-Activity Relationship ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New Thienobenzo/Naphtho-Triazoles as Butyrylcholinesterase Inhibitors: Design, Synthesis and Computational Study.
Autorzy:
Mlakić, Milena (AUTHOR)
Selec, Ida (AUTHOR)
Ćaleta, Irena (AUTHOR)
Odak, Ilijana (AUTHOR)
Barić, Danijela (AUTHOR)
Ratković, Ana (AUTHOR)
Molčanov, Krešimir (AUTHOR)
Škorić, Irena (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 6, p5879. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Comprehensive Review of Cholinesterase Modeling and Simulation.
Autorzy:
De Boer D; Department of Chemistry & Biochemistry, California State University, Long Beach, CA 90840, USA.
Nguyen N; Department of Chemical Engineering, California State University, Long Beach, CA 90840, USA.
Mao J; Department of Chemical Engineering, California State University, Long Beach, CA 90840, USA.
Moore J; Department of Biomedical Engineering, California State University, Long Beach, CA 90840, USA.
Sorin EJ; Department of Chemistry & Biochemistry, California State University, Long Beach, CA 90840, USA.
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Źródło:
Biomolecules [Biomolecules] 2021 Apr 15; Vol. 11 (4). Date of Electronic Publication: 2021 Apr 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Quantitative Structure-Activity Relationship*
Cholinesterase Inhibitors/*chemistry
Cholinesterases/*chemistry
Molecular Docking Simulation/*methods
Animals ; Cholinesterase Inhibitors/pharmacology ; Cholinesterases/metabolism ; Drug Design ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids.
Autorzy:
Maříková J; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Mamun AA; ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Shammari LA; ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Korábečný J; Department of Toxicology and Military Pharmacy, University of Defence, Trenesska 1575, 500 05 Hradec Kralove, Czech Republic.; Biomedical Research Centre, University Hospital Hradec Králové, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
Kučera T; Department of Toxicology and Military Pharmacy, University of Defence, Trenesska 1575, 500 05 Hradec Kralove, Czech Republic.
Hulcová D; ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.; Department of Pharmacognosy, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Kuneš J; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Malaník M; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, Palackeho trida 1946/1, 612 00 Brno, Czech Republic.
Vašková M; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 500 03 Hradec Kralove, Czech Republic.
Kohelová E; ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Nováková L; Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Cahlíková L; ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
Pour M; Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 26; Vol. 26 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids/*chemistry
Amaryllidaceae Alkaloids/*chemistry
Cholinesterase Inhibitors/*chemistry
Cholinesterases/*ultrastructure
Alkaloids/pharmacology ; Alzheimer Disease ; Amaryllidaceae Alkaloids/pharmacology ; Butyrylcholinesterase/chemistry ; Butyrylcholinesterase/ultrastructure ; Catalytic Domain/drug effects ; Cholinesterase Inhibitors/pharmacology ; Cholinesterases/chemistry ; Circular Dichroism ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
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