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Tytuł :
Downregulation of MicroRNA-495 Alleviates IL-1β Responses among Chondrocytes by Preventing SOX9 Reduction.
Autorzy :
Joung S; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Yoon DS; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Cho S; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Ko EA; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Lee KM; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Park KH; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Lee JW; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Kim SH; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.; Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Korea.; Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. .
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Źródło :
Yonsei medical journal [Yonsei Med J] 2021 Jul; Vol. 62 (7), pp. 650-659.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*/metabolism
Interleukin-1beta*/metabolism
MicroRNAs*/genetics
SOX9 Transcription Factor*/genetics
SOX9 Transcription Factor*/metabolism
Cells, Cultured ; Down-Regulation ; Humans
Czasopismo naukowe
Tytuł :
Proteomic Analysis of Synovial Fibroblasts and Articular Chondrocytes Co-Cultures Reveals Valuable VIP-Modulated Inflammatory and Degradative Proteins in Osteoarthritis.
Autorzy :
Pérez-García S; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Calamia V; Rheumatology Research Group, INIBIC-Biomedical Research Institute, CICA-University of A Coruña, 15006 A Coruña, Spain.
Hermida-Gómez T; Rheumatology Research Group, INIBIC-Biomedical Research Institute, CICA-University of A Coruña, 15006 A Coruña, Spain.
Gutiérrez-Cañas I; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Carrión M; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Villanueva-Romero R; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Castro D; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Martínez C; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Juarranz Y; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
Blanco FJ; Rheumatology Research Group, INIBIC-Biomedical Research Institute, CICA-University of A Coruña, 15006 A Coruña, Spain.
Gomariz RP; Department of Cell Biology, Faculty of Biology and Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 16; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
Proteome*
Proteomics*/methods
Chondrocytes/*metabolism
Fibroblasts/*metabolism
Osteoarthritis/*metabolism
Synovial Membrane/*cytology
Vasoactive Intestinal Peptide/*metabolism
Biomarkers ; Chondrocytes/drug effects ; Coculture Techniques ; Cytokines/metabolism ; Disease Susceptibility ; Extracellular Matrix/metabolism ; Fibroblasts/drug effects ; Humans ; Inflammation Mediators/metabolism ; Osteoarthritis/etiology ; Osteoarthritis/pathology ; Vasoactive Intestinal Peptide/pharmacology
Czasopismo naukowe
Tytuł :
Nuclear Magnetic Resonance Therapy Modulates the miRNA Profile in Human Primary OA Chondrocytes and Antagonizes Inflammation in Tc28/2a Cells.
Autorzy :
Steinecker-Frohnwieser B; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, 5760 Saalfelden, Austria.
Lohberger B; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, 5760 Saalfelden, Austria.; Department of Orthopedics and Trauma, Medical University Graz, 8036 Graz, Austria.
Eck N; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, 5760 Saalfelden, Austria.; Department of Orthopedics and Trauma, Medical University Graz, 8036 Graz, Austria.
Mann A; Division of Special Anaesthesia and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Kratschmann C; Division of Special Anaesthesia and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Leithner A; Department of Orthopedics and Trauma, Medical University Graz, 8036 Graz, Austria.
Kullich W; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, 5760 Saalfelden, Austria.
Weigl L; Division of Special Anaesthesia and Pain Medicine, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 31; Vol. 22 (11). Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*/cytology
Chondrocytes*/metabolism
Chondrocytes*/pathology
Osteoarthritis*/metabolism
Osteoarthritis*/therapy
Magnetic Resonance Spectroscopy/*methods
MicroRNAs/*metabolism
Cell Line ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Fibrin Gel Suspended Autologous Chondrocytes as Cell-based Material for long-term Injection Laryngoplasty.
Autorzy :
Stefanie Buchberger AM; Department of Phoniatrics and Pedaudiology, Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Nitiu R; Department of Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Pinther M; Department of Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Graf S; Department of Phoniatrics and Pedaudiology, Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Skodacek D; Department of Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Regn S; Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.
Kreutzer K; Department of Maxillofacial Surgery, University clinic of the Charité Berlin, Berlin, Germany.
Storck K; Department of Ear-Nose-Throat, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
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Źródło :
The Laryngoscope [Laryngoscope] 2021 May; Vol. 131 (5), pp. E1624-E1632. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrocytes/*transplantation
Fibrin/*chemistry
Laryngoplasty/*methods
Vocal Cord Paralysis/*therapy
Animals ; Cell Culture Techniques/methods ; Chondrocytes/chemistry ; Chondrogenesis/physiology ; Disease Models, Animal ; Ear Cartilage/cytology ; Female ; Gels ; Humans ; Injections, Intralesional ; Male ; Primary Cell Culture ; Rabbits ; Transplantation, Autologous ; Vocal Cord Paralysis/pathology ; Vocal Cords/innervation ; Vocal Cords/pathology
Czasopismo naukowe
Tytuł :
Xanthohumol suppresses inflammation in chondrocytes and ameliorates osteoarthritis in mice.
Autorzy :
Chen X; Department of Orthopaedics, Affiliated Hospital of Guilin Medical College, Guilin, Guangxi Province, China; Zhejiang Provincial Key Laboratory of Orthopedics, Wenzhou, Zhejiang Province, China.
Li Z; Department of Orthopaedics, Affiliated Hospital of Guilin Medical College, Guilin, Guangxi Province, China.
Hong H; The Second School of Medicine, Wenzhou Medical University. Wenzhou, Zhejiang Province, China.
Wang N; Department of Orthopaedics, Affiliated Hospital of Guilin Medical College, Guilin, Guangxi Province, China.
Chen J; Department of Orthopaedics, Affiliated Hospital of Guilin Medical College, Guilin, Guangxi Province, China.
Lu S; The Second School of Medicine, Wenzhou Medical University. Wenzhou, Zhejiang Province, China.
Zhang H; The Second School of Medicine, Wenzhou Medical University. Wenzhou, Zhejiang Province, China.
Zhang X; Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China; Zhejiang Provincial Key Laboratory of Orthopedics, Wenzhou, Zhejiang Province, China; The Second School of Medicine, Wenzhou Medical University. Wenzhou, Zhejiang Province, China. Electronic address: .
Bei C; Department of Orthopaedics, Affiliated Hospital of Guilin Medical College, Guilin, Guangxi Province, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111238. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Chondrocytes/*drug effects
Flavonoids/*pharmacology
Inflammation Mediators/*metabolism
Joints/*drug effects
Osteoarthritis/*drug therapy
Propiophenones/*pharmacology
Animals ; Cells, Cultured ; Chondrocytes/metabolism ; Chondrocytes/pathology ; Cyclooxygenase 2/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Joints/metabolism ; Joints/pathology ; Male ; Mice, Inbred C57BL ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
AKAP2 overexpression modulates growth plate chondrocyte functions through ERK1/2 signaling.
Autorzy :
Wang B; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Jiang B; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Li Y; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China. Electronic address: .
Dai Y; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Li P; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Li L; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Xu J; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Li L; Department of Spine Surgery, The Second Xiangya Hospital, Central South University, China.
Wu P; Center for Medical Genetics, School of Life Sciences, Central South University, China.
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Źródło :
Bone [Bone] 2021 May; Vol. 146, pp. 115875. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrocytes*
Growth Plate*/metabolism
A Kinase Anchor Proteins/genetics ; A Kinase Anchor Proteins/metabolism ; Adolescent ; Cell Proliferation ; Cells, Cultured ; Humans ; MAP Kinase Signaling System ; Membrane Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Dynamic loading enhances chondrogenesis of human chondrocytes within a biodegradable resilient hydrogel.
Autorzy :
Xie M; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. , Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China.
Fritch M; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. .
He Y; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. .
Fu H; Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA. .
Hong Y; Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA. .
Lin H; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA. and Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA 15219, USA and McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
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Źródło :
Biomaterials science [Biomater Sci] 2021 Jul 13; Vol. 9 (14), pp. 5011-5024.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Chondrogenesis*
Animals ; Cartilage ; Cells, Cultured ; Humans ; Hydrogels ; Ion Channels ; Mice ; TRPV Cation Channels ; Tissue Engineering ; Tissue Scaffolds
Czasopismo naukowe
Tytuł :
Evaluation of osteochondral-like tissues using human freeze-dried cancellous bone and chondrocyte sheets to treat osteochondral defects in rabbits.
Autorzy :
Wongin S; Biological Engineering Program, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Bangkok 10140, Thailand. .
Wangdee C; Department of Veterinary Surgery, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand. .
Nantavisai S; Special Task Force for Activating Research (STAR) in Biology of Embryo and Stem Cell Research in Veterinary Science, Veterinary Stem Cells and Bioengineering Innovation Center (VSCBIC), Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand. .
Banlunara W; Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand. .
Nakbunnum R; Department of Orthopedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. .
Waikakul S; Department of Orthopedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. .
Chotiyarnwong P; Department of Orthopedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. .
Roytrakul S; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Thailand Science Park, Pathum Thani, 12120, Thailand. .
Viravaidya-Pasuwat K; Biological Engineering Program, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Bangkok 10140, Thailand. and Department of Chemical Engineering, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Bangkok 10140, Thailand. .
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Źródło :
Biomaterials science [Biomater Sci] 2021 Jul 07; Vol. 9 (13), pp. 4701-4716. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cartilage, Articular*
Chondrocytes*
Animals ; Cancellous Bone ; Collagen Type II ; Proteomics ; Rabbits
Czasopismo naukowe
Tytuł :
Long-term exposure to the fluoride blocks the development of chondrocytes in the ducks: The molecular mechanism of fluoride regulating autophagy and apoptosis.
Autorzy :
Wang Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Li A; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Mehmood K; Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Hussain R; Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Abbas RZ; Department of Parasitology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38040, Pakistan.
Javed MT; Department of Pathology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38040, Pakistan.
Chang YF; College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Hu L; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Pan J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Li Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shi L; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address: .
Tang Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address: .
Zhang H; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jul 01; Vol. 217, pp. 112225. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes/*physiology
Ducks/*physiology
Fluorides/*toxicity
Animals ; Apoptosis/drug effects ; Autophagy/drug effects ; Beclin-1/metabolism ; Chondrocytes/drug effects ; Chondrogenesis ; Fluorides/metabolism ; Growth Plate
Czasopismo naukowe
Tytuł :
FOXO1 expression in chondrocytes modulates cartilage production and removal in fracture healing.
Autorzy :
Ding Z; Department of Pediatric Dentistry, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Qiu M; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthopaedic Surgery, Shengjing Hospital, China Medical University, Shenyang, China.
Alharbi MA; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Endodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Huang T; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Pei X; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; First Clinical Division, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, China.
Milovanova TN; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jiao H; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lu C; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Liu M; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Qin L; McKay Orthopaedic Research Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Graves DT; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło :
Bone [Bone] 2021 Jul; Vol. 148, pp. 115905. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chondrocytes*
Fracture Healing*
Animals ; Bony Callus ; Cartilage ; Forkhead Box Protein O1/genetics ; Mice ; Osteoclasts
Czasopismo naukowe
Tytuł :
Comparison of chondro-inductivity between collagen and hyaluronic acid hydrogel based on chemical/physical microenvironment.
Autorzy :
Yang J; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China; Research Center for Human Tissue and Organs Degeneration, Institute Biomedical and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangzhou, China.
Tang Z; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Liu Y; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Luo Z; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
Xiao Y; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China. Electronic address: .
Zhang X; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 61004, Sichuan, China.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 1941-1952. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cellular Microenvironment/*drug effects
Chondrocytes/*cytology
Collagen/*pharmacology
Hyaluronic Acid/*pharmacology
Hydrogels/*pharmacology
Adsorption ; Animals ; Biomechanical Phenomena ; Blood Proteins/metabolism ; Cattle ; Cell Differentiation/drug effects ; Cell Shape/drug effects ; Cell Survival/drug effects ; Chondrocytes/drug effects ; Chondrogenesis/drug effects ; Diffusion ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Gene Expression Regulation/drug effects ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Rabbits ; Static Electricity ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Chlorogenic Acid retards cartilaginous endplate degeneration and ameliorates intervertebral disc degeneration via suppressing NF-κB signaling.
Autorzy :
Ge Q; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Ying J; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.
Shi Z; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Mao Q; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.
Jin H; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China.
Wang PE; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China.
Chen J; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yuan W; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China.
Tong P; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China. Electronic address: .
Li J; Institute of Orthopaedics and Traumatology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jun 01; Vol. 274, pp. 119324. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Cartilage/*drug effects
Chlorogenic Acid/*pharmacology
Chondrocytes/*drug effects
Gene Expression Regulation/*drug effects
Intervertebral Disc Degeneration/*drug therapy
NF-kappa B/*antagonists & inhibitors
Animals ; Cartilage/pathology ; Cells, Cultured ; Chondrocytes/pathology ; Intervertebral Disc Degeneration/metabolism ; Intervertebral Disc Degeneration/pathology ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Effect of the defect localization and size on the success of third-generation autologous chondrocyte implantation in the knee joint.
Autorzy :
Niethammer TR; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany. .
Gallik D; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Chevalier Y; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Holzgruber M; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Baur-Melnyk A; Institute of Clinical Radiology, Ludwig-Maximilians-University Munich, Grosshadern Campus, Marchioninistr. 15, 81377, Munich, Germany.
Müller PE; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Pietschmann MF; Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University Hospital of Munich (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
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Źródło :
International orthopaedics [Int Orthop] 2021 Jun; Vol. 45 (6), pp. 1483-1491. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji :
Journal Article
MeSH Terms :
Cartilage, Articular*/surgery
Chondrocytes*
Follow-Up Studies ; Humans ; Knee Joint/surgery ; Transplantation, Autologous
Czasopismo naukowe
Tytuł :
High cyclic tensile stress disrupts the extracellular matrix in human chondrocyte by F-actin cytoskeletal polymerization and reactive oxygen species production.
Autorzy :
Li Y; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Yang J; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Feng Q; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Li SQ; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Lang Y; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Zhang XF; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Ye C; Department of Orthopaedic Surgery, Fuyang Orthopaedics and Traumatology Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Źródło :
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2021 May-Jun; Vol. 35 (3), pp. 965-974.
Typ publikacji :
Journal Article
MeSH Terms :
Actins*
Chondrocytes*
Actin Cytoskeleton ; Cells, Cultured ; Extracellular Matrix ; Humans ; Polymerization ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
Mechanobiological Interactions between Dynamic Compressive Loading and Viscoelasticity on Chondrocytes in Hydrazone Covalent Adaptable Networks for Cartilage Tissue Engineering.
Autorzy :
Richardson BM; Department of Chemical and Biological Engineering, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; The BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.
Walker CJ; The BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; Materials Science and Engineering Program, University of Colorado Boulder, 4001 Discovery Drive, Boulder, CO, 80303, USA.
Maples MM; Department of Chemical and Biological Engineering, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; The BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.
Randolph MA; Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, WAC 435, Boston, MA, 02114, USA.; Division of Plastic Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman St, WACC 453, Boston, MA, 02114, USA.
Bryant SJ; Department of Chemical and Biological Engineering, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; The BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; Materials Science and Engineering Program, University of Colorado Boulder, 4001 Discovery Drive, Boulder, CO, 80303, USA.
Anseth KS; Department of Chemical and Biological Engineering, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.; The BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO, 80303, USA.
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Źródło :
Advanced healthcare materials [Adv Healthc Mater] 2021 May; Vol. 10 (9), pp. e2002030. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cartilage, Articular*
Chondrocytes*
Compressive Strength ; Hydrazones ; Stress, Mechanical ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Use of in vitro assays to identify antibiotics that are cytotoxic to normal equine chondrocytes and synovial cells.
Autorzy :
Pezzanite L; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Chow L; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Piquini G; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Griffenhagen G; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Ramirez D; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Dow S; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Goodrich L; Translational Medicine Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
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Źródło :
Equine veterinary journal [Equine Vet J] 2021 May; Vol. 53 (3), pp. 579-589. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cartilage, Articular*
Chondrocytes*
Animals ; Anti-Bacterial Agents/toxicity ; Horses
Czasopismo naukowe
Tytuł :
Cross-talk between synovial fibroblasts and chondrocytes in condylar hyperplasia: an in vitro pilot study.
Autorzy :
Guo H; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education (KLOBM), School and Hospital of Stomatology, Wuhan University, Wuhan, China; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Li H; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education (KLOBM), School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Feng Y; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education (KLOBM), School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Ke J; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education (KLOBM), School and Hospital of Stomatology, Wuhan University, Wuhan, China; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Fang W; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education (KLOBM), School and Hospital of Stomatology, Wuhan University, Wuhan, China; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Li C; Department of Stomatology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Long X; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, China. Electronic address: .
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Źródło :
Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2021 May; Vol. 131 (5), pp. 558-564. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Fibroblasts*
Tissue Inhibitor of Metalloproteinase-1*
Mandible/*pathology
Antigens, CD34 ; Cells, Cultured ; Fibroblast Growth Factor 2 ; Humans ; Hyperplasia/pathology ; Pilot Projects ; Synovial Membrane/cytology ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Tytuł :
Alpha-1-antitrypsin reduces inflammation and exerts chondroprotection in arthritis.
Autorzy :
Kaneva MK; The William Harvey Research Institute, The London School of Medicine, Queen Mary University of London, London, UK.
Muley MM; Departments of Pharmacology and Anaesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Halifax, NS, Canada.
Krustev E; Departments of Pharmacology and Anaesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Halifax, NS, Canada.
Reid AR; Departments of Pharmacology and Anaesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Halifax, NS, Canada.
Souza PR; The William Harvey Research Institute, The London School of Medicine, Queen Mary University of London, London, UK.
Dell'Accio F; The William Harvey Research Institute, The London School of Medicine, Queen Mary University of London, London, UK.; Centre for inflammation and Therapeutic Innovation, Queen Mary University of London, London, UK.
McDougall JJ; Departments of Pharmacology and Anaesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Halifax, NS, Canada.
Perretti M; The William Harvey Research Institute, The London School of Medicine, Queen Mary University of London, London, UK.; Centre for inflammation and Therapeutic Innovation, Queen Mary University of London, London, UK.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21472.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chondrogenesis*
Arthritis, Experimental/*complications
Chondrocytes/*cytology
Inflammation/*prevention & control
Pain/*prevention & control
alpha 1-Antitrypsin/*pharmacology
Animals ; Chondrocytes/drug effects ; Inflammation/etiology ; Inflammation/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Pain/etiology ; Pain/pathology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Oxygen-generating microparticles in chondrocytes-laden hydrogels by facile and versatile click chemistry strategy.
Autorzy :
de Sousa Araújo E; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Domingues Stocco T; Faculty of Medical Sciences, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil; University of Santo Amaro, São Paulo, SP, 04829-300, Brazil.
Fernandes de Sousa G; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Afewerki S; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States; Division of Health Sciences and Technology, Harvard University ‒ Massachusetts Institute of Technology (MIT), Cambridge, MA, 02139, United States. Electronic address: .
Marciano FR; Department of Physics, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Alexandre Finzi Corat M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Michelle Machado de Paula M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Ferreira Cândido Lima Verde T; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil.
Cristina Moreira Silva M; Multidisciplinary Center for Biological Research, Unicamp - State University of Campinas, Campinas, SP, 13083-877, Brazil.
Oliveira Lobo A; LIMAV-Interdisciplinary Laboratory for Advanced Materials, BioMatLab, UFPI - Federal University of Piaui, Teresina, PI, 64049-550, Brazil; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, United States. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2021 Sep; Vol. 205, pp. 111850. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chondrocytes*
Hydrogels*
Click Chemistry ; Oxygen ; Tissue Engineering
Czasopismo naukowe
Tytuł :
Enhanced miRNA-140 expression of osteoarthritis-affected human chondrocytes cultured in a polymer based three-dimensional (3D) matrix.
Autorzy :
Katoh S; Edogawa Evolutionary Lab of Science, Edogawa Hospital Campus, 2-24-18, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan; Department of Orthopaedic Surgery, Edogawa Hospital, 2-24-18, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan.
Yoshioka H; Mebiol Inc., 1-25-8, Nakahara, Hiratsuka 254-0075, Kanagawa, Japan.
Senthilkumar R; The Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India.
Preethy S; The Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India.
Abraham SJK; The Mary-Yoshio Translational Hexagon (MYTH), Nichi-In Centre for Regenerative Medicine (NCRM), PB 1262, Chennai 600034, Tamil Nadu, India; JBM Inc., 3-1-14, Higashi Koiwa, Edogawa, Tokyo 133-0052, Japan; University of Yamanashi -Faculty of Medicine, 1110, Shimokato, Chuo, Yamanashi 409-3898, Japan; GN Corporation Co. Ltd., 3-8, Wakamatsu, Kofu, Yamanashi 400-0866, Japan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Aug 01; Vol. 278, pp. 119553. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Chondrocytes/*pathology
MicroRNAs/*genetics
Osteoarthritis/*genetics
Cell Culture Techniques ; Cells, Cultured ; Chondrocytes/metabolism ; Humans ; Osteoarthritis/pathology ; Polymers/chemistry ; Tissue Scaffolds/chemistry
Czasopismo naukowe

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