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You search for a phrase ""Christopher J. Lord"" according to the criterion: Author

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Showing 1-20 from 29 results
Title:
Resistance to DNA repair inhibitors in cancer
Authors:
Joseph S. Baxter
Diana Zatreanu
Stephen J. Pettitt
Christopher J. Lord
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Subject Terms:
ATR
Cancer
DDR
PARP
PolQ
WRN
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Source:
Molecular Oncology, Vol 16, Iss 21, Pp 3811-3827 (2022)
File Description:
electronic resource
Relation:
https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261
Access URL:
https://doaj.org/article/e87726dbc3f540c286c4a2cae2a824aa  Link opens in a new window
Academic Journal
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Title:
Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency
Authors:
Ilirjana Bajrami
Callum Walker
Dragomir B. Krastev
Daniel Weekes
Feifei Song
Andrew J. Wicks
John Alexander
Syed Haider
Rachel Brough
Stephen J. Pettitt
Andrew N. J. Tutt
Christopher J. Lord
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Subject Terms:
Biology (General)
QH301-705.5
Source:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2399-3642
Access URL:
https://doaj.org/article/d5f5e8c9681d4c1cb2934f06ed9a1386  Link opens in a new window
Academic Journal
Full Text  Link opens in a new windowDetails
Title:
Opinion: PARP inhibitors in cancer—what do we still need to know?
Authors:
Andrew J. Wicks
Dragomir B. Krastev
Stephen J. Pettitt
Andrew N. J. Tutt
Christopher J. Lord
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Subject Terms:
PARP inhibitors
cancer
synthetic lethality
biomarkers
drug resistance
Biology (General)
QH301-705.5
Source:
Open Biology, Vol 12, Iss 7 (2022)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2046-2441
Access URL:
https://doaj.org/article/4b60bfc0f8324ff39565168634c77471  Link opens in a new window
Academic Journal
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Title:
Beyond DNA repair: the novel immunological potential of PARP inhibitors
Authors:
Roman M. Chabanon
Jean-Charles Soria
Christopher J. Lord
Sophie Postel-Vinay
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Subject Terms:
dna damage response
dna repair defects
parp inhibitors
cgas/sting
tumour cell-intrinsic immunity
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Source:
Molecular & Cellular Oncology, Vol 6, Iss 2, Pp 1-4 (2019)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2372-3556
Access URL:
https://doaj.org/article/d47bb605b76545a88a86206288006b5b  Link opens in a new window
Academic Journal
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Title:
Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets
Authors:
Dragomir B. Krastev
Stephen J. Pettitt
James Campbell
Feifei Song
Barbara E. Tanos
Stoyno S. Stoynov
Alan Ashworth
Christopher J. Lord
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Subject Terms:
Science
Source:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2041-1723
Access URL:
https://doaj.org/article/6b4485c994204db1bfb5e33371cc705b  Link opens in a new window
Academic Journal
Details
Title:
Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer
Authors:
Agnieszka K. Witkiewicz
Sejin Chung
Rachel Brough
Paris Vail
Jorge Franco
Christopher J. Lord
Erik S. Knudsen
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Subject Terms:
Biology (General)
QH301-705.5
Source:
Cell Reports, Vol 22, Iss 5, Pp 1185-1199 (2018)
File Description:
electronic resource
Relation:
http://www.sciencedirect.com/science/article/pii/S2211124718300391; https://doaj.org/toc/2211-1247
Access URL:
https://doaj.org/article/3487547192bb459398b96c12f7aa104f  Link opens in a new window
Academic Journal
Details
Title:
ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
Authors:
Chris T. Williamson
Rowan Miller
Helen N. Pemberton
Samuel E. Jones
James Campbell
Asha Konde
Nicholas Badham
Rumana Rafiq
Rachel Brough
Aditi Gulati
Colm J. Ryan
Jeff Francis
Peter B. Vermulen
Andrew R. Reynolds
Philip M. Reaper
John R. Pollard
Alan Ashworth
Christopher J. Lord
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Subject Terms:
Science
Source:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2041-1723
Access URL:
https://doaj.org/article/e641244f3cf24d9e87d1e6540b5b48bf  Link opens in a new window
Academic Journal
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Title:
A Machine-Learning Tool Concurrently Models Single Omics and Phenome Data for Functional Subtyping and Personalized Cancer Medicine
Authors:
Gift Nyamundanda
Katherine Eason
Justin Guinney
Christopher J. Lord
Anguraj Sadanandam
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Subject Terms:
machine learning
breast cancer
continuous subtypes
functional subtypes
CDK inhibitor
etoposide
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Source:
Cancers, Vol 12, Iss 10, p 2811 (2020)
File Description:
electronic resource
Relation:
https://www.mdpi.com/2072-6694/12/10/2811; https://doaj.org/toc/2072-6694
Access URL:
https://doaj.org/article/42b22fdebfee45f7aa65bf0bb9afed25  Link opens in a new window
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Correction: A Modified Method for Whole Exome Resequencing from Minimal Amounts of Starting DNA.
Authors:
Iwanka Kozarewa
Juan Manuel Rosa-Rosa
Christopher P. Wardell
Brian A. Walker
Kerry Fenwick
Ioannis Assiotis
Costas Mitsopoulos
Marketa Zvelebil
Gareth J. Morgan
Alan Ashworth
Christopher J. Lord
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Subject Terms:
Medicine
Science
Source:
PLoS ONE, Vol 7, Iss 4 (2012)
File Description:
electronic resource
Relation:
http://europepmc.org/articles/PMC3321049; https://doaj.org/toc/1932-6203
Access URL:
https://doaj.org/article/0c767bc59ddb4da3a702a28feb4e0269  Link opens in a new window
Academic Journal
Details
Title:
Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions
Authors:
Christopher J Lord
Niall Quinn
Colm J Ryan
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Subject Terms:
genetic interactions
synthetic lethality
cancer
protein-protein interactions
genetic heterogeneity
Medicine
Science
Biology (General)
QH301-705.5
Source:
eLife, Vol 9 (2020)
File Description:
electronic resource
Relation:
https://elifesciences.org/articles/58925; https://doaj.org/toc/2050-084X
Access URL:
https://doaj.org/article/8e586e747ad4476bb5d11047dd6bd123  Link opens in a new window
Academic Journal
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Title:
Longitudinal analysis of a secondary BRCA2 mutation using digital droplet PCR
Authors:
Saira Khalique
Stephen J Pettitt
Ger Kelly
Nina Tunariu
Rachael Natrajan
Susana Banerjee
Christopher J Lord
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Subject Terms:
PARP inhibitor
drug resistance
cancer
BRCA2
digital droplet PCR
Pathology
RB1-214
Source:
The Journal of Pathology: Clinical Research, Vol 6, Iss 1, Pp 3-11 (2020)
File Description:
electronic resource
Relation:
https://doaj.org/toc/2056-4538
Access URL:
https://doaj.org/article/e8f9e42757ad4610a7b154b67b6a4093  Link opens in a new window
Academic Journal
Details
Title:
Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.
Authors:
Andrey A Parkhitko
Arashdeep Singh
Sharon Hsieh
Yanhui Hu
Richard Binari
Christopher J Lord
Sridhar Hannenhalli
Colm J Ryan
Norbert Perrimon
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Subject Terms:
Genetics
QH426-470
Source:
PLoS Genetics, Vol 17, Iss 2, p e1009354 (2021)
File Description:
electronic resource
Relation:
https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404
Access URL:
https://doaj.org/article/5d7da79486b143a8a4352f9eed0f8e17  Link opens in a new window
Academic Journal
Full Text  Link opens in a new windowDetails
Showing 1-20 from 29 results

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