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    Tytuł:
    TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.
    Autorzy:
    Arita H; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. .; Department of Neurosurgery, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita-City, Osaka, 565-0871, Japan. .
    Matsushita Y; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Machida R; Biostatistics Division, Center for Research Administration and Support, National Cancer Center, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Yamasaki K; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.; Department of Pediatric Hematology and Oncology, Osaka City General Hospital, 2-13-22, Miyakojima-hondori, Miyakojima-ku, Osaka-City, Osaka, 534-0021, Japan.
    Hata N; Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka-City, Fukuoka, 812-8582, Japan.
    Ohno M; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Yamaguchi S; Department of Neurosurgery, Faculty of Medicine, Hokkaido University, North 15 West 7, Kita-ku, Sapporo-City, Hokkaido, 060-8638, Japan.
    Sasayama T; Department of Neurosurgery, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe-City, Hyogo, 650-0017, Japan.
    Tanaka S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
    Higuchi F; Department of Neurosurgery, Dokkyo Medical University, 880, Kitakobayashi, Mibu-City, Tochigi, 321-0293, Japan.
    Iuchi T; Division of Neurological Surgery, Chiba Cancer Center, 666-2 Nitonacho, Chuo-ku, Chiba-City, Chiba, 260-8717, Japan.
    Saito K; Department of Neurosurgery, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-City, Tokyo, 181-8611, Japan.
    Kanamori M; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai-City, Miyagi, 980-8574, Japan.
    Matsuda KI; Department of Neurosurgery, Faculty of Medicine, Yamagata University, 2-2, Iida-Nishi, Yamagata-City, Yamagata, 990-9585, Japan.
    Miyake Y; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka-City, Saitama, 350-1298, Japan.; Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama-City, Kanagawa, 236-0004, Japan.
    Tamura K; Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
    Tamai S; Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, 13-1, Takara-machi, Kanazawa-City, Ishikawa, 920-8641, Japan.
    Nakamura T; Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama-City, Kanagawa, 236-0004, Japan.
    Uda T; Department of Neurosurgery, Osaka City University Graduate School of Medicine, 1-5-7, Asahi-machi, Abeno-ku, Osaka-City, Osaka, 545-8586, Japan.
    Okita Y; Department of Neurosurgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka-City, Osaka, 540-0006, Japan.; Department of Neurosurgery, Osaka International Cancer Institute, 3-1-69, Otemae, Chuo-ku, Osaka-City, Osaka, 541-8567, Japan.
    Fukai J; Department of Neurological Surgery, Wakayama Medical University, 811-1, Kimiidera, Wakayama-City, Wakayama, 641-0012, Japan.
    Sakamoto D; Department of Neurosurgery, Hyogo College of Medicine, 1-1 Mukogawa, Nishinomiya-City, Hyogo, 663-8501, Japan.
    Hattori Y; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-City, Okayama, 700-8558, Japan.
    Pareira ES; Department of Neurosurgery, Keio University School of Medicine, 35, Shinano-machi, Tokyo, Shinjuku-ku, 160-8582, Japan.
    Hatae R; Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka-City, Fukuoka, 812-8582, Japan.
    Ishi Y; Department of Neurosurgery, Faculty of Medicine, Hokkaido University, North 15 West 7, Kita-ku, Sapporo-City, Hokkaido, 060-8638, Japan.
    Miyakita Y; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Tanaka K; Department of Neurosurgery, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe-City, Hyogo, 650-0017, Japan.
    Takayanagi S; Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
    Otani R; Department of Neurosurgery, Dokkyo Medical University, 880, Kitakobayashi, Mibu-City, Tochigi, 321-0293, Japan.; Department of Neurosurgery, Tokyo Metropolitan Komagome Hospital, 3-18-22, Honkomagome, Bunkyo-ku, Tokyo, 113-8677, Japan.
    Sakaida T; Division of Neurological Surgery, Chiba Cancer Center, 666-2 Nitonacho, Chuo-ku, Chiba-City, Chiba, 260-8717, Japan.
    Kobayashi K; Department of Neurosurgery, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-City, Tokyo, 181-8611, Japan.
    Saito R; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai-City, Miyagi, 980-8574, Japan.
    Kurozumi K; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-City, Okayama, 700-8558, Japan.
    Shofuda T; Department of Biomedical Research and Innovation Research, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, 2-1-14, Hoenzaka, Chuo-ku, Osaka-City, Osaka, 540-0006, Japan.
    Nonaka M; Department of Neurosurgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka-City, Osaka, 540-0006, Japan.; Department of Neurosurgery, Kansai Medical University, 3-1, Shinmachi 2 Chome, Hirakata-City, Osaka, 573-1191, Japan.
    Suzuki H; Department of Pathology and Laboratory Medicine, National Hospital Organization, Sendai Medical Center, 2-11-12, Miyagino, Miyagino-ku, Sendai-City, Miyagi, 983-8520, Japan.
    Shibuya M; Central Clinical Laboratory, Hachioji Medical Center, Tokyo Medical University, 1163, Tatemachi, Hachioji-City, Tokyo, 193-0998, Japan.
    Komori T; Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu, Tokyo, 183-0042, Japan.
    Sasaki H; Department of Neurosurgery, Keio University School of Medicine, 35, Shinano-machi, Tokyo, Shinjuku-ku, 160-8582, Japan.
    Mizoguchi M; Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka-City, Fukuoka, 812-8582, Japan.
    Kishima H; Department of Neurosurgery, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita-City, Osaka, 565-0871, Japan.
    Nakada M; Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, 13-1, Takara-machi, Kanazawa-City, Ishikawa, 920-8641, Japan.
    Sonoda Y; Department of Neurosurgery, Faculty of Medicine, Yamagata University, 2-2, Iida-Nishi, Yamagata-City, Yamagata, 990-9585, Japan.
    Tominaga T; Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai-City, Miyagi, 980-8574, Japan.
    Nagane M; Department of Neurosurgery, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-City, Tokyo, 181-8611, Japan.
    Nishikawa R; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka-City, Saitama, 350-1298, Japan.
    Kanemura Y; Department of Neurosurgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka-City, Osaka, 540-0006, Japan.; Department of Biomedical Research and Innovation Research, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, 2-1-14, Hoenzaka, Chuo-ku, Osaka-City, Osaka, 540-0006, Japan.
    Kuchiba A; Biostatistics Division, Center for Research Administration and Support, National Cancer Center, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Narita Y; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    Ichimura K; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. .
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    Źródło:
    Acta neuropathologica communications [Acta Neuropathol Commun] 2020 Nov 23; Vol. 8 (1), pp. 201. Date of Electronic Publication: 2020 Nov 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Brain Neoplasms/*genetics
    Glioma/*genetics
    Promoter Regions, Genetic/*genetics
    Telomerase/*genetics
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Astrocytoma/genetics ; Astrocytoma/pathology ; Astrocytoma/therapy ; Brain Neoplasms/pathology ; Brain Neoplasms/therapy ; Female ; Glioblastoma/genetics ; Glioblastoma/pathology ; Glioblastoma/therapy ; Glioma/pathology ; Glioma/therapy ; Humans ; Isocitrate Dehydrogenase/genetics ; Karnofsky Performance Status ; Male ; Middle Aged ; Multivariate Analysis ; Mutation ; Neoplasm Grading ; Neurosurgical Procedures ; Oligodendroglioma/genetics ; Oligodendroglioma/pathology ; Oligodendroglioma/therapy ; Prognosis ; Proportional Hazards Models ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Rate ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Determining chromosomal arms 1p/19q co-deletion status in low graded glioma by cross correlation-periodogram pattern analysis.
    Autorzy:
    Bhattacharya D; Networking and Communication, International Institute of Information Technology, Bangalore, 560100, India.
    Sinha N; Networking and Communication, International Institute of Information Technology, Bangalore, 560100, India. .
    Saini J; Neuroimaging and interventional radiology, National Institute of Mental Health and Neuro Science, Bengaluru, 560029, India.
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    Źródło:
    Scientific reports [Sci Rep] 2021 Dec 13; Vol. 11 (1), pp. 23866. Date of Electronic Publication: 2021 Dec 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Glioma/*genetics
    Magnetic Resonance Imaging/*methods
    Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Glioma/diagnostic imaging ; Glioma/pathology ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Loss of H3K27 trimethylation is frequent in IDH1-R132H but not in non-canonical IDH1/2 mutated and 1p/19q codeleted oligodendroglioma: a Japanese cohort study.
    Autorzy:
    Habiba U; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.; Department of Oral Pathology and Periodontology, Sapporo Dental College and Hospital, Dhaka, Bangladesh.
    Sugino H; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
    Yordanova R; Department of Mathematics, Faculty of Science, Hokkaido University, Sapporo, Japan.; Institute of Mathematics and Informatics, Bulgarian Academy of Sciences, Sofia, Bulgaria.
    Ise K; School of Medicine, Hokkaido University, Sapporo, Japan.
    Tanei ZI; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
    Ishida Y; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.
    Tanikawa S; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan.
    Terasaka S; Kashiwaba Neurosurgical Hospital, Sapporo, Japan.
    Sato KI; Nakamura Memorial Hospital, Sapporo, Japan.
    Kamoshima Y; Asabu Neurosurgical Hospital, Sapporo, Japan.
    Katoh M; Hokkaido Neurosurgical Memorial Hospital, Sapporo, Japan.
    Nagane M; Department of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan.
    Shibahara J; Department of Pathology, Kyorin University School of Medicine, Tokyo, Japan.
    Tsuda M; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan.; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan.; Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Japan.
    Tanaka S; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-Ku, Sapporo, 060-8638, Japan. .; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan. .; Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Japan. .
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    Źródło:
    Acta neuropathologica communications [Acta Neuropathol Commun] 2021 May 21; Vol. 9 (1), pp. 95. Date of Electronic Publication: 2021 May 21.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Isocitrate Dehydrogenase/*genetics
    Oligodendroglioma/*genetics
    Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Humans ; Japan/epidemiology ; Male ; Middle Aged ; Mutation/genetics ; Oligodendroglioma/epidemiology ; Oligodendroglioma/pathology ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    1p/19q co-deletion status is associated with distinct tumor-associated macrophage infiltration in IDH mutated lower-grade gliomas.
    Autorzy:
    Zhang Y; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Biomedical Center, Box 582, BMC, Husargatan 3, 75123, Uppsala, Sweden.
    Xie Y; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
    He L; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Key Laboratory of Post-Neuro-injury Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, 300052, China.; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbeck Laboratory, 75185, Uppsala, Sweden.
    Tang J; Department of Spine Surgery, Huaihua No.2 Hospital, Hunan University of Medicine, Huaihua, 418000, China.
    He Q; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
    Cao Q; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
    Cui L; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
    Guo W; Department of Neurosurgery, Tangdu Hospital, Air Force Medical University of PLA (the Fourth Military Medical University), 569 Xinsi Road, Xi'an, 710038, China.
    Hua K; The College of Life Sciences, Northwest University, Xi'an, 710069, China.
    Dimberg A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbeck Laboratory, 75185, Uppsala, Sweden.
    Wang L; Department of Neurosurgery, Tangdu Hospital, Air Force Medical University of PLA (the Fourth Military Medical University), 569 Xinsi Road, Xi'an, 710038, China. .
    Zhang L; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China. .; Department of Spine Surgery, Huaihua No.2 Hospital, Hunan University of Medicine, Huaihua, 418000, China. .
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    Źródło:
    Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Feb; Vol. 44 (1), pp. 193-204. Date of Electronic Publication: 2020 Sep 11.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Chromosome Deletion*
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Glioma/*genetics
    Isocitrate Dehydrogenase/*genetics
    Mutation/*genetics
    Tumor-Associated Macrophages/*pathology
    Animals ; Brain Neoplasms/pathology ; Disease Progression ; Female ; Glioma/pathology ; Humans ; Macrophage Colony-Stimulating Factor/metabolism ; Mice, Inbred C57BL ; Monocytes/pathology ; Neoplasm Grading ; Phenotype ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; THP-1 Cells ; Transforming Growth Factor beta1/metabolism ; Tumor-Associated Macrophages/metabolism ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Detection of chromosome structural variation by targeted next-generation sequencing and a deep learning application.
    Autorzy:
    Park H; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Chun SM; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Center for Cancer Genome Discovery, Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Shim J; Institute of Statistical Information, Department of Statistics, Inje University, Gyeongsangnam-do, Korea.
    Oh JH; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Cho EJ; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Hwang HS; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Lee JY; Center for Cancer Genome Discovery, Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Kim D; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Center for Cancer Genome Discovery, Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Jang SJ; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.; Center for Cancer Genome Discovery, Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Nam SJ; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Hwang C; Department of Applied Statistics, Dankook University, Gyeonggido, Korea. .
    Sohn I; Biostatistics and Clinical Epidemiology Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea. .
    Sung CO; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. .; Center for Cancer Genome Discovery, Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. .; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Mar 06; Vol. 9 (1), pp. 3644. Date of Electronic Publication: 2019 Mar 06.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Aberrations*
    Chromosome Structures*
    Deep Learning*
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    High-Throughput Nucleotide Sequencing/*methods
    Oligodendroglioma/*genetics
    Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Oligodendroglioma/classification ; Oligodendroglioma/diagnosis ; Retrospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion.
    Autorzy:
    Gladitz J; Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
    Klink B; Institute for Clinical Genetics, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; National Center for Tumor Diseases, Dresden, Germany.
    Seifert M; Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. .; National Center for Tumor Diseases, Dresden, Germany. .
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    Źródło:
    Acta neuropathologica communications [Acta Neuropathol Commun] 2018 Jun 11; Vol. 6 (1), pp. 49. Date of Electronic Publication: 2018 Jun 11.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Neoplasm Proteins/*genetics
    Oligodendroglioma/*genetics
    Chromosomes, Human, Pair 1/genetics ; Computational Biology ; Female ; Gene Dosage ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Male ; Metabolic Networks and Pathways/genetics ; Mutation/genetics ; Neoplasm Proteins/metabolism ; Signal Transduction/genetics ; Succinate Dehydrogenase/genetics ; Vesicular Glutamate Transport Protein 1/genetics
    SCR Disease Name:
    Chromosome 1, monosomy 1p
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Impact of TCF3 rearrangement on CNS relapse in egyptian pediatric acute lymphoblastic leukemia.
    Autorzy:
    ElGendi HM; 1Department of Clinical Pathology, Ain Shams University, Cairo, Egypt.
    Abdelmaksoud AA
    Eissa DG
    Abusikkien SA
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    Źródło:
    Pediatric hematology and oncology [Pediatr Hematol Oncol] 2014 Oct; Vol. 31 (7), pp. 638-46. Date of Electronic Publication: 2014 Aug 12.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Translocation, Genetic*
    Central Nervous System Neoplasms/*genetics
    Oncogene Proteins, Fusion/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
    Adolescent ; Central Nervous System Neoplasms/drug therapy ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Oncogene Proteins, Fusion/analysis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Recurrence
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    ImmunoFISH is a reliable technique for the assessment of 1p and 19q status in oligodendrogliomas.
    Autorzy:
    Duval C; Department of Pathology, Centre Hospitalier Universitaire de Québec, Québec, Canada.
    de Tayrac M; Department of genomic and molecular genetics, Centre Hospitalier Universitaire de Rennes, Rennes, France.
    Sanschagrin F; Department of Pathology, Centre Hospitalier Universitaire de Québec, Québec, Canada.
    Michaud K; Department of Neurosurgery, Centre Hospitalier Universitaire de Québec, Québec, Canada.
    Gould PV; Department of Pathology, Centre Hospitalier Universitaire de Québec, Québec, Canada.
    Saikali S; Department of Pathology, Centre Hospitalier Universitaire de Québec, Québec, Canada.
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    Źródło:
    PloS one [PLoS One] 2014 Jun 20; Vol. 9 (6), pp. e100342. Date of Electronic Publication: 2014 Jun 20 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Antinuclear/*metabolism
    Antibodies, Monoclonal/*metabolism
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    In Situ Hybridization, Fluorescence/*methods
    Oligodendroglioma/*genetics
    Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/metabolism ; Chromosomes, Human, Pair 1/metabolism ; Chromosomes, Human, Pair 19/metabolism ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Observer Variation ; Oligodendroglioma/metabolism ; Reproducibility of Results
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Static and dynamic F-FET PET for the characterization of gliomas defined by IDH and 1p/19q status.
    Autorzy:
    Verger A; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany. .; Department of Nuclear Medicine & Nancyclotep Imaging Platform, CHRU Nancy, Lorraine University, Nancy, France. .; IADI, INSERM, UMR 947, Lorraine University, Nancy, France. .; Service de Médecine Nucléaire, Rue du Morvan, 54500, Vandoeuvre-les-Nancy, France. .
    Stoffels G; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.
    Bauer EK; Department of Neurology, University Hospital Cologne, Cologne, Germany.
    Lohmann P; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.
    Blau T; Department of Neuropathology, University Hospital Cologne, Cologne, Germany.
    Fink GR; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.; Department of Neurology, University Hospital Cologne, Cologne, Germany.
    Neumaier B; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.
    Shah NJ; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.; Department of Neurology, RWTH Aachen University Hospital, Aachen, Germany.; Section JARA-Brain, Juelich-Aachen Research Alliance (JARA), Juelich, Germany.
    Langen KJ; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.; Section JARA-Brain, Juelich-Aachen Research Alliance (JARA), Juelich, Germany.; Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany.
    Galldiks N; Institute of Neuroscience and Medicine (INM-3, INM-4, INM-5), Forschungszentrum Jülich, Jülich, Germany.; Department of Neurology, University Hospital Cologne, Cologne, Germany.; Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Cologne, Germany.
    Pokaż więcej
    Źródło:
    European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2018 Mar; Vol. 45 (3), pp. 443-451. Date of Electronic Publication: 2017 Oct 17.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Positron-Emission Tomography*
    Chromosomes, Human, Pair 19/*genetics
    Glioma/*diagnostic imaging
    Glioma/*genetics
    Isocitrate Dehydrogenase/*genetics
    Tyrosine/*analogs & derivatives
    Adult ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/enzymology ; Brain Neoplasms/genetics ; Chromosome Deletion ; Chromosomes, Human, Pair 1/genetics ; Female ; Glioma/enzymology ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies
    SCR Disease Name:
    Chromosome 1, monosomy 1p
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Analysis of CIC-associated CpG island methylation in oligoastrocytoma.
    Autorzy:
    Sahm F; Department of Neuropathology, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuropathology G380, German Cancer Research Center (DKFZ), Heidelberg, Germany.
    Lass U
    Herold-Mende C
    von Deimling A
    Hartmann C
    Mueller W
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    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2013 Dec; Vol. 39 (7), pp. 831-6.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    DNA Methylation*/genetics
    Brain Neoplasms/*genetics
    CpG Islands/*genetics
    Oligodendroglioma/*genetics
    Brain Neoplasms/pathology ; Genetic Predisposition to Disease ; Humans ; Loss of Heterozygosity/genetics ; Mutation/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    1p/19q testing has no significance in the workup of glioblastomas.
    Autorzy:
    Clark KH; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
    Villano JL
    Nikiforova MN
    Hamilton RL
    Horbinski C
    Pokaż więcej
    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2013 Oct; Vol. 39 (6), pp. 706-17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosome Deletion*
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Brain Neoplasms/*diagnosis
    Glioblastoma/*diagnosis
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brain/pathology ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Female ; Genes, Neoplasm ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Male ; Middle Aged ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Histological spectrum of oligodendroglial tumors: Only a subset shows 1p/19q codeletion.
    Autorzy:
    Pai T; Division of Molecular Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Epari S; Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Desai S; Division of Molecular Pathology, Tata Memorial Centre, Mumbai, Maharashtra; Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Wadile A; Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Gupta T; Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Goda JS; Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Moiyadi A; Department of Neurosurgery, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Shetty P; Department of Neurosurgery, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Kane S; Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Jalali R; Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
    Pokaż więcej
    Źródło:
    Neurology India [Neurol India] 2017 Jan-Feb; Vol. 65 (1), pp. 113-120.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain Neoplasms*/epidemiology
    Brain Neoplasms*/genetics
    Brain Neoplasms*/pathology
    Chromosome Deletion*
    Glioblastoma*/epidemiology
    Glioblastoma*/genetics
    Glioblastoma*/pathology
    Oligodendroglioma*/epidemiology
    Oligodendroglioma*/genetics
    Oligodendroglioma*/pathology
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Adolescent ; Adult ; Aged ; Child ; Cohort Studies ; Female ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Impact of 1p/19q codeletion on the diagnosis and prognosis of different grades of meningioma.
    Autorzy:
    Basaran R; a Department of Neurosurgery , Istanbul Medeniyet University, Goztepe Education and Research Hospital , Istanbul , Turkey ;
    Uslu S; b Department of Histology and Embryology , Istanbul Medeniyet University School of Medicine , Istanbul , Turkey ;
    Gucluer B; c Department of Pathology , Istanbul Medeniyet University, Goztepe Education and Research Hospital , Istanbul , Turkey ;
    Onoz M; d Department of Neurosurgery , Memorial Hospital , Istanbul , Turkey ;
    Isik N; a Department of Neurosurgery , Istanbul Medeniyet University, Goztepe Education and Research Hospital , Istanbul , Turkey ;
    Tiryaki M; e Department of Neurosurgery , Dr. Lutfi Kirdar Kartal Education and Research Hospital , Istanbul , Turkey ;
    Yakicier C; f Department of Molecular Genetics, Acibadem University School of Medicine , Istanbul , Turkey ;
    Sav A; g Department of Pathology, Acibadem University School of Medicine , Istanbul , Turkey.
    Elmaci I; d Department of Neurosurgery , Memorial Hospital , Istanbul , Turkey ;
    Pokaż więcej
    Źródło:
    British journal of neurosurgery [Br J Neurosurg] 2016 Oct; Vol. 30 (5), pp. 571-6. Date of Electronic Publication: 2016 May 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Chromosome Deletion*
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Meningioma/*diagnosis
    Meningioma/*genetics
    Adult ; Aged ; Aged, 80 and over ; Chromosome Aberrations ; Female ; Gene Amplification ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Ki-67 Antigen/analysis ; Male ; Meningioma/therapy ; Middle Aged ; Neoplasm Grading ; Prognosis ; Retrospective Studies ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1.
    Autorzy:
    Jeha S; Department of Oncology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
    Pei D
    Raimondi SC
    Onciu M
    Campana D
    Cheng C
    Sandlund JT
    Ribeiro RC
    Rubnitz JE
    Howard SC
    Downing JR
    Evans WE
    Relling MV
    Pui CH
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 2009 Aug; Vol. 23 (8), pp. 1406-9. Date of Electronic Publication: 2009 Mar 12.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Translocation, Genetic*
    Central Nervous System/*pathology
    Chromosomes, Human, Pair 1/*ultrastructure
    Chromosomes, Human, Pair 19/*ultrastructure
    Leukemic Infiltration/*epidemiology
    Oncogene Proteins, Fusion/*genetics
    Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
    Adolescent ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Child ; Child, Preschool ; Chromosomes, Human, Pair 1/genetics ; Chromosomes, Human, Pair 19/genetics ; Clinical Trials as Topic/statistics & numerical data ; Combined Modality Therapy ; Cranial Irradiation ; Disease-Free Survival ; Female ; Genotype ; Humans ; Incidence ; Infant ; Injections, Spinal ; Leukemic Infiltration/prevention & control ; Male ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/epidemiology ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/radiotherapy ; Prognosis ; Proportional Hazards Models ; Risk ; Risk Assessment ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Correlation of chromosomes 1p and 19q status and expressions of O6-methylguanine DNA methyltransferase (MGMT), p53 and Ki-67 in diffuse gliomas of World Health Organization (WHO) grades II and III: a clinicopathological study.
    Autorzy:
    Huang L; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing.; Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, and.
    Jiang T; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing.
    Yuan F; Beijing Neurosurgical Institute, Beijing, China.
    Li GL; Beijing Neurosurgical Institute, Beijing, China.
    Cui Y; Beijing Neurosurgical Institute, Beijing, China.
    Liu EZ; Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, and.
    Wang ZC; Beijing Neurosurgical Institute, Beijing, China.
    Pokaż więcej
    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2009 Aug; Vol. 35 (4), pp. 367-379. Date of Electronic Publication: 2008 Nov 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    DNA Modification Methylases/*metabolism
    DNA Repair Enzymes/*metabolism
    Glioma/*genetics
    Ki-67 Antigen/*metabolism
    Tumor Suppressor Protein p53/*metabolism
    Tumor Suppressor Proteins/*metabolism
    Adolescent ; Adult ; Aged ; Astrocytoma/genetics ; Astrocytoma/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Child ; DNA Modification Methylases/genetics ; DNA Repair Enzymes/genetics ; Female ; Gene Expression ; Glioma/metabolism ; Humans ; Ki-67 Antigen/genetics ; Loss of Heterozygosity ; Male ; Middle Aged ; Neoplasm Staging ; Oligodendroglioma/genetics ; Oligodendroglioma/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q.
    Autorzy:
    Tews B; Division of Molecular Genetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
    Roerig P
    Hartmann C
    Hahn M
    Felsberg J
    Blaschke B
    Sabel M
    Kunitz A
    Toedt G
    Neben K
    Benner A
    von Deimling A
    Reifenberger G
    Lichter P
    Pokaż więcej
    Źródło:
    Oncogene [Oncogene] 2007 Jul 26; Vol. 26 (34), pp. 5010-6. Date of Electronic Publication: 2007 Feb 19.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Loss of Heterozygosity*
    Brain Neoplasms/*genetics
    Oligodendroglioma/*genetics
    Transcription Factors/*genetics
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/mortality ; Child ; CpG Islands ; DNA Methylation ; Down-Regulation ; Female ; Gene Silencing ; Humans ; Male ; Middle Aged ; Oligodendroglioma/mortality ; Polymorphism, Genetic ; Survival Analysis ; Transcription Factors/biosynthesis ; Transcription, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis.
    Autorzy:
    Mazieres J; UCSF Comprehensive Cancer Center, San Francisco, CA 94115, USA.
    You L
    He B
    Xu Z
    Lee AY
    Mikami I
    McCormick F
    Jablons DM
    Pokaż więcej
    Źródło:
    Oncogene [Oncogene] 2005 Aug 11; Vol. 24 (34), pp. 5396-400.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Translocation, Genetic*
    Apoptosis/*genetics
    Glycoproteins/*physiology
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology
    Gene Expression Profiling ; Glycoproteins/biosynthesis ; Glycoproteins/genetics ; Humans ; RNA, Small Interfering ; Reverse Transcriptase Polymerase Chain Reaction ; Tumor Cells, Cultured ; Up-Regulation ; Wnt Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A genome-wide screen for genes influencing conduct disorder.
    Autorzy:
    Dick DM; Indiana University, 975 West Walnut St., IB-130, Indianapolis, IN 46202-5251, USA.
    Li TK
    Edenberg HJ
    Hesselbrock V
    Kramer J
    Kuperman S
    Porjesz B
    Bucholz K
    Goate A
    Nurnberger J
    Foroud T
    Pokaż więcej
    Źródło:
    Molecular psychiatry [Mol Psychiatry] 2004 Jan; Vol. 9 (1), pp. 81-6.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Genome, Human*
    Lod Score*
    Conduct Disorder/*genetics
    Adult ; Alcoholism/genetics ; Child ; Genetic Testing ; Humans ; Retrospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Detection of E2A translocations in leukemias via fluorescence in situ hybridization.
    Autorzy:
    Boomer T; Department of Pediatrics, University of Colorado School of Medicine, Denver, CO, USA.
    Varella-Garcia M
    McGavran L
    Meltesen L
    Olsen AS
    Hunger SP
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    Źródło:
    Leukemia [Leukemia] 2001 Jan; Vol. 15 (1), pp. 95-102.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 17*
    Chromosomes, Human, Pair 19*
    Translocation, Genetic*
    Leukemia/*genetics
    Transcription Factors/*genetics
    Basic Helix-Loop-Helix Transcription Factors ; DNA-Binding Proteins/genetics ; Homeodomain Proteins/genetics ; Humans ; In Situ Hybridization, Fluorescence ; Oncogene Proteins, Fusion/genetics ; Transcription Factors/analysis ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype.
    Autorzy:
    Smith JS; Division of Laboratory Genetics, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
    Alderete B
    Minn Y
    Borell TJ
    Perry A
    Mohapatra G
    Hosek SM
    Kimmel D
    O'Fallon J
    Yates A
    Feuerstein BG
    Burger PC
    Scheithauer BW
    Jenkins RB
    Pokaż więcej
    Źródło:
    Oncogene [Oncogene] 1999 Jul 15; Vol. 18 (28), pp. 4144-52.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Sequence Deletion*
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Glioma/*genetics
    Astrocytoma/genetics ; Astrocytoma/pathology ; Brain Neoplasms/pathology ; Chromosomes, Human, Pair 1/ultrastructure ; Chromosomes, Human, Pair 19/ultrastructure ; Glioma/classification ; Glioma/pathology ; Humans ; In Situ Hybridization, Fluorescence ; Loss of Heterozygosity ; Oligodendroglioma/genetics ; Oligodendroglioma/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The gene encoding the granulocyte colony-stimulating factor receptor is a target for deregulation in pre-B ALL by the t(1;19)-specific oncoprotein E2A-Pbx1.
    Autorzy:
    de Lau WB; Academic Hospital Utrecht, Department of Immunology, The Netherlands.
    Hurenkamp J
    Berendes P
    Touw IP
    Clevers HC
    van Dijk MA
    Pokaż więcej
    Źródło:
    Oncogene [Oncogene] 1998 Jul 30; Vol. 17 (4), pp. 503-10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1*
    Chromosomes, Human, Pair 19*
    Gene Expression Regulation*
    Translocation, Genetic*
    Burkitt Lymphoma/*genetics
    Homeodomain Proteins/*metabolism
    Oncogene Proteins, Fusion/*metabolism
    Receptors, Granulocyte Colony-Stimulating Factor/*genetics
    B-Lymphocytes ; Burkitt Lymphoma/metabolism ; Hematopoietic Stem Cells ; Homeodomain Proteins/genetics ; Humans ; Oncogene Proteins, Fusion/genetics ; Receptors, Granulocyte Colony-Stimulating Factor/physiology ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Anaplastic oligodendroglioma arising from the brain stem and featuring 1p/19q co-deletion.
    Autorzy:
    Hewer E; Institute of Pathology, University of Bern, Bern, Switzerland.
    Beck J
    Vassella E
    Vajtai I
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    Źródło:
    Neuropathology : official journal of the Japanese Society of Neuropathology [Neuropathology] 2014 Feb; Vol. 34 (1), pp. 32-8. Date of Electronic Publication: 2013 May 27.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Brain Stem Neoplasms/*diagnosis
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Oligodendroglioma/*diagnosis
    Brain Stem Neoplasms/genetics ; Brain Stem Neoplasms/pathology ; Chromosome Deletion ; Female ; Humans ; Middle Aged ; Oligodendroglioma/genetics ; Oligodendroglioma/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Fluorescence in situ hybridization for 1p, 19q status in a cohort of glial neoplasms.
    Autorzy:
    Singh VY
    Chacko G; Section of Neuropathology, Departments of Neurological Sciences and Pathology, Section of Neurosurgery, Christian Medical College, Vellore, Tamil Nadu, India.
    Chacko AG
    Rajshekhar V
    Pokaż więcej
    Źródło:
    Neurology India [Neurol India] 2014 Jan-Feb; Vol. 62 (1), pp. 32-6.
    Typ publikacji:
    Journal Article; Observational Study
    MeSH Terms:
    Chromosome Deletion*
    Astrocytoma/*genetics
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Oligodendroglioma/*genetics
    Adult ; Astrocytoma/metabolism ; Astrocytoma/pathology ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cross-Sectional Studies ; ErbB Receptors/metabolism ; Female ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Neoplasm Staging ; Oligodendroglioma/metabolism ; Oligodendroglioma/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Coexistence of translocation(1,19) and the Philadelphia chromosome in a child's first presentation of chronic myeloid leukemia in blast crisis treated with dasatinib.
    Autorzy:
    Eckardt MA; Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
    Chang VY
    Rao NP
    Federman N
    Pokaż więcej
    Źródło:
    Pediatric hematology and oncology [Pediatr Hematol Oncol] 2011 Nov; Vol. 28 (8), pp. 669-75.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Philadelphia Chromosome*
    Blast Crisis/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
    Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*therapy
    Pyrimidines/*therapeutic use
    Thiazoles/*therapeutic use
    Adolescent ; Blast Crisis/diagnosis ; Blast Crisis/therapy ; Bone Marrow Transplantation ; Dasatinib ; Fatal Outcome ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas.
    Autorzy:
    Bralten LB; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
    Nouwens S
    Kockx C
    Erdem L
    Hoogenraad CC
    Kros JM
    Moorhouse MJ
    Sillevis Smitt PA
    van der Spek P
    van Ijcken W
    Stubbs A
    French PJ
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2011; Vol. 6 (7), pp. e22000. Date of Electronic Publication: 2011 Jul 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Genes, Neoplasm/*genetics
    Mutation/*genetics
    Oligodendroglioma/*genetics
    Adult ; Case-Control Studies ; CpG Islands/genetics ; DNA Methylation/genetics ; Female ; Genetic Association Studies ; Guanine Nucleotide Exchange Factors/genetics ; Humans ; Male ; Promoter Regions, Genetic/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Can morphology predict 1p/19q loss in oligodendroglial tumours?
    Autorzy:
    Scheie D; Division of Pathology, Rikshospitalet University Hospital, Oslo, Norway. />Cvancarova M
    Mørk S
    Skullerud K
    Andresen PA
    Benestad I
    Helseth E
    Meling T
    Beiske K
    Pokaż więcej
    Źródło:
    Histopathology [Histopathology] 2008 Nov; Vol. 53 (5), pp. 578-87.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Loss of Heterozygosity/*genetics
    Oligodendroglioma/*genetics
    Adult ; Aged ; Cohort Studies ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Neoplasms/genetics ; Neoplasms/pathology ; Oligodendroglioma/pathology ; Phenotype
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Chromosome 1p and 19q status and p53 and p16 expression patterns as prognostic indicators of oligodendroglial tumors: a clinicopathological study using fluorescence in situ hybridization.
    Autorzy:
    Jeon YK; Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
    Park K
    Park CK
    Paek SH
    Jung HW
    Park SH
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    Źródło:
    Neuropathology : official journal of the Japanese Society of Neuropathology [Neuropathology] 2007 Feb; Vol. 27 (1), pp. 10-20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Brain Neoplasms/*genetics
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Genes, p16/*physiology
    Genes, p53/*physiology
    Oligodendroglioma/*genetics
    Adult ; Aged ; Brain Neoplasms/metabolism ; Brain Neoplasms/mortality ; Female ; Gene Expression ; Gene Expression Profiling ; Glial Fibrillary Acidic Protein/biosynthesis ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Mutation ; Oligodendroglioma/metabolism ; Oligodendroglioma/mortality ; Polymerase Chain Reaction ; Prognosis ; Survival Analysis ; Tissue Array Analysis ; Tumor Suppressor Protein p53/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Poor outcome of adult acute lymphoblastic leukemia patients carrying the (1;19)(q23;p13) translocation.
    Autorzy:
    Piccaluga PP; Institute of Haematology and Medical Oncology 'L. and A. Serànoli', S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. />Malagola M
    Rondoni M
    Ottaviani E
    Testoni N
    Laterza C
    Visani G
    Pileri SA
    Martinelli G
    Baccarani M
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    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2006 Mar; Vol. 47 (3), pp. 469-72.
    Typ publikacji:
    Case Reports; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Translocation, Genetic*
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*therapy
    Adult ; Bone Marrow Transplantation ; Cytogenetic Analysis ; Fatal Outcome ; Female ; Humans ; Male ; Middle Aged ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Prognosis ; Recurrence ; Treatment Failure
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia.
    Autorzy:
    Prima V; Department of Pediatrics, University of Florida College of Medicine and the University of Florida Shands Cancer Center, Gainesville, FL 32610, USA.
    Gore L
    Caires A
    Boomer T
    Yoshinari M
    Imaizumi M
    Varella-Garcia M
    Hunger SP
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    Źródło:
    Leukemia [Leukemia] 2005 May; Vol. 19 (5), pp. 806-13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 1/*genetics
    Chromosomes, Human, Pair 19/*genetics
    DNA-Binding Proteins/*physiology
    Oncogene Proteins, Fusion/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
    RNA-Binding Proteins/*physiology
    Transcription Factors/*physiology
    Cell Line, Tumor ; Cloning, Molecular ; DNA/metabolism ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Humans ; MADS Domain Proteins ; MEF2 Transcription Factors ; Molecular Sequence Data ; Myogenic Regulatory Factors ; RNA/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Transcription Factors/chemistry ; Transcription Factors/genetics ; Translocation, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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