- Tytuł:
- Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors.
- Autorzy:
- Źródło:
- Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2017 Dec; Vol. 32 (1), pp. 821-831.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Isoxazoles/*pharmacology
Leukocyte Elastase/*antagonists & inhibitors
Serine Proteinase Inhibitors/*pharmacology
Dose-Response Relationship, Drug ; Humans ; Isoxazoles/chemical synthesis ; Isoxazoles/chemistry ; Leukocyte Elastase/metabolism ; Molecular Structure ; Serine Proteinase Inhibitors/chemical synthesis ; Serine Proteinase Inhibitors/chemistry ; Structure-Activity Relationship
Czasopismo naukowe